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- Pushko, Peter, et al. Show all 6 Authors
- Vaccine 2013 v.31 no.7 pp. 1019-1025
- RNA; Venezuelan equine encephalitis virus; adverse effects; animal models; encephalitis; horses; humans; immunity; live vaccines; mice; plasmids; recombinant vaccines; vaccination; viruses
- ... DNA vaccines combine remarkable genetic and chemical stability with proven safety and efficacy in animal models, while remaining less immunogenic in humans. In contrast, live-attenuated vaccines have the advantage of inducing rapid, robust, long-term immunity after a single-dose vaccination. Here we describe novel iDNA vaccine technology that is based on an infectious DNA platform and combines adv ...
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