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- Wright, Ernest M., et al. Show all 5 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2013 v.110 no.47 pp. E4557
- binding sites; carbohydrate binding; cysteine; dissociation; genes; glucose; humans; leucine; mutants; mutation; sodium; symporters
- ... Sodium cotransporters from several different gene families belong to the leucine transporter (LeuT) structural family. Although the identification of Na ⁺ in binding sites is beyond the resolution of the structures, two Na ⁺ binding sites (Na1 and Na2) have been proposed in LeuT. Na2 is conserved in the LeuT family but Na1 is not. A biophysical method has been used to measure sodium dissociation c ...
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