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You searched for: Author "Qu, Zhican" Remove constraint Author: "Qu, Zhican" Publication Year 2012 Remove constraint Publication Year: 2012 Subject endothelial cells Remove constraint Subject: endothelial cells
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1. Serotonin activates angiogenic phosphorylation signaling in human endothelial cells

Author:
Qu, Zhican,   et al.   ; Zamani, Ali;     Show all 2 Author
Source:
FEBS letters 2012 v.586 no.16 pp. 2360-2365
ISSN:
0014-5793
Subject:
G-protein coupled receptors; angiogenesis; endothelial cells; humans; phosphorylation; platelet aggregation; serotonin; signal transduction; therapeutics; vascular endothelial growth factors
Abstract:
... Serotonin, a known neurotransmitter, also functions as an angiokine to promote angiogenesis. The majority of serotonin in the human body is stored in platelets, and platelet aggregation leads to significant release of serotonin in thrombotic tumor environment. We have investigated serotonin signaling in human endothelial cells. Through G-protein-coupled receptors, serotonin at physiologically rele ...
DOI:
10.1016/j.febslet.2012.05.047