Jump to Main Content
- Qiu, Zhi-Gang, et al. Show all 8 Authors
- Environmental Science & Technology 2012 v.46 no.24 pp. 13448-13454
- Escherichia coli; ampicillin; antibiotic resistance; cephalosporins; drugs; genes; genetic engineering; human health; humans; metagenomics; microorganisms; nucleotide sequences; plasmid vectors; plasmids; pollution; quantitative polymerase chain reaction; recombinant DNA; risk; rivers; surveys
- ... Antibiotic resistance poses a significant challenge to human health and its rate continues to rise globally. While antibiotic-selectable synthetic plasmid vectors have proved invaluable tools of genetic engineering, this class of artificial recombinant DNA sequences with high expression of antibiotic resistance genes presents an unknown risk beyond the laboratory setting. Contamination of environm ...