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- Chen, Shuaiyin, et al. Show all 4 Authors
- Current microbiology 2011 v.62 no.6 pp. 1726-1731
- Helicobacter pylori; Lactococcus lactis; Western blotting; gastritis; genes; lactose; nisin; plasmids; polymerase chain reaction; vaccines
- ... Helicobacter pylori is the principal cause of chronic active gastritis, peptic ulcer, and gastric cancer. To develop an oral vaccine against H. pylori infection, we had expressed the H. pylori ureB gene (Genbank accession no. FJ436980) in nisin-controlled expression vectors using Lactococcus lactis NZ3900 as host. The ureB gene was amplified by PCR from a H.pylori strain MEL-Hp27. Then the ureB ge ...