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- Ziegler, Andreas, et al. Show all 12 Authors
- Genomics 2011 v.98 no.5 pp. 320-326
- autosomes; females; genes; genetic variation; humans; males; microarray technology; monocytes; quantitative trait loci
- ... In humans, the fraction of X-linked genes with higher expression in females has been estimated to be 5% from microarray studies, a proportion lower than the 25% of genes thought to escape X inactivation. We analyzed 715 X-linked transcripts in circulating monocytes from 1,467 subjects and found an excess of female-biased transcripts on the X compared to autosomes (9.4% vs 5.5%, p<2×10⁻⁵). Among th ...