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- Liu, Ye V., et al. Show all 7 Authors
- Vaccine 2011 v.29 no.38 pp. 6606-6613
- Severe acute respiratory syndrome coronavirus; aluminum hydroxide; chimerism; death; glycoproteins; immune response; influenza; insects; mice; models; neutralizing antibodies; pandemic; people; viral load; virus-like particle vaccines; virus-like particles; weight loss
- ... SARS-CoV was the cause of the global pandemic in 2003 that infected over 8000 people in 8 months. Vaccines against SARS are still not available. We developed a novel method to produce high levels of a recombinant SARS virus-like particles (VLPs) vaccine containing the SARS spike (S) protein and the influenza M1 protein using the baculovirus insect cell expression system. These chimeric SARS VLPs h ...
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