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- Horvath, Tamas L., et al. Show all 2 Author
- Cell 2011 v.146 no.6 pp. 863-865
- feeding behavior; hormones; hunger; hypothalamus; hysteresis; neurons; satiety
- ... The drive to eat is controlled by neuronal circuits in the hypothalamus that respond to hormones signaling hunger or satiety. In this issue of Cell, Yang et al. (2011) reveal an AMPK-dependent synaptic pathway that sustains excitatory stimulation of the NPY/AgRP neurons that promote feeding behavior until satiety signals kick in. ...
- Horvath, Tamas L., et al. Show all 10 Authors
- Physiology & behavior 2011 v.105 no.1 pp. 43-51
- cold stress; energy expenditure; food intake; ghrelin; ghrelin receptors; humans; hypothermia; intravenous injection; mice; neurons; preoptic area; rats; risk; surface temperature; thermoregulation
- ... Ghrelin increases food intake and decreases energy expenditure, promoting a positive energy balance. We observed a single case of serious hypothermia during sustained ghrelin treatment in a male subject, suggesting that ghrelin may play a role in the regulation of body temperature. We therefore investigated the effect of ghrelin treatment on body temperature in rodents and humans under controlled ...
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- Horvath, Tamas L., et al. Show all 11 Authors
- Science 2011 v.332 no.6035 pp. 1330-1332
- appetite; cholinergic receptors; electrophysiology; food intake; mice; neurons; nicotine; obesity; pro-opiomelanocortin; smoke; smoking (habit)
- ... Smoking decreases appetite, and smokers often report that they smoke to control their weight. Understanding the neurobiological mechanisms underlying the anorexic effects of smoking would facilitate the development of novel treatments to help with smoking cessation and to prevent or treat obesity. By using a combination of pharmacological, molecular genetic, electrophysiological, and feeding studi ...
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