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- Johnson, Derrick, et al. Show all 20 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2011 v.108 no.43 pp. 17797-17802
- crosslinking; humans; hydrophobicity; lipid bilayers; micelles; models; nuclear magnetic resonance spectroscopy; phospholipids; phosphorus
- ... A heterologously expressed form of the human Parkinson disease-associated protein α-synuclein with a 10-residue N-terminal extension is shown to form a stable tetramer in the absence of lipid bilayers or micelles. Sequential NMR assignments, intramonomer nuclear Overhauser effects, and circular dichroism spectra are consistent with transient formation of α-helices in the first 100 N-terminal resid ...
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