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- Tappin, Inger, et al. Show all 9 Authors
- Nucleic acids research 2010 v.38 no.19 pp. 6466-6476
- DNA replication; genome; humans; in vitro studies; interphase; mitochondria; mitochondrial DNA
- ... Mammalian mitochondria contain full-length genome and a single-stranded 7S DNA. Although the copy number of mitochondrial DNA (mtDNA) varies depending on the cell type and also in response to diverse environmental stresses, our understanding of how mtDNA and 7S DNA are maintained and regulated is limited, partly due to lack of reliable in vitro assay systems that reflect the in vivo functionality ...
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