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- Carbajal, Kevin S.; Schaumburg, Christopher; Strieter, Robert; Kane, Joy; Lane, Thomas E.
- Proceedings of the National Academy of Sciences of the United States of America 2010 v.107 no.24 pp. 11068-11073
- Murine hepatitis virus, etc ; CXCR4 receptor; atypical chemokine receptor 3; axons; blood serum; central nervous system; chemokine CXCL12; humans; inflammation; mice; models; myelin sheath; oligodendroglia; sclerosis; stem cells; viruses; Show all 16 Subjects
- ... Multiple sclerosis (MS) is a human demyelinating disease characterized by multifocal regions of inflammation, progressive myelin loss within the central nervous system (CNS), and eventual failure to remyelinate damaged axons. These problems suggest deficiencies in recruiting and/or maturation of oligodendrocyte progentior cells (OPCs) and highlight cell replacement therapies to promote remyelinati ...
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