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- Harada, Tsuyoshi, et al. Show all 6 Authors
- Journal of nutritional biochemistry 2010 v.21 no.4 pp. 268-277
- dietary fat; omega-3 fatty acids; eicosapentaenoic acid; neurophysiology; neuroprotective effect; nervous system diseases; brain; Alzheimer disease; learning; memory; cognitive development; cognition; long term effects; hippocampus; synaptic transmission; free fatty acids; phosphatidylinositol 3-kinase; nutrition-genotype interaction; neuroglia; docosahexaenoic acid; phosphorylation; neurons; epidemiological studies
- ... Placebo-controlled clinical studies suggest that intake of n-3 polyunsaturated fatty acids improves neurological disorders such as Alzheimer's disease, Huntington's disease and schizophrenia. To evaluate the impact of eicosapentaenoic acid (EPA), we orally administered highly purified ethyl EPA (EPA-E) to rats at a dose of 1.0 mg/g per day and measured long-term potentiation of the CA1 hippocampal ...