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- Lau, Anthony G.; Irier, Hasan A.; Gu, Jiaping; Tian, Donghua; Ku, Li; Liu, Guanglu; Xia, Mingjing; Fritsch, Brita; Zheng, James Q.; Dingledine, Raymond; Xu, Baoji; Lu, Bai; Feng, Yue
- Proceedings of the National Academy of Sciences of the United States of America 2010 v.107 no.36 pp. 15945-15950
- pilocarpine, etc ; 3' untranslated regions; gene expression regulation; hippocampus; neurons; receptor protein-tyrosine kinase; transcription (genetics); Show all 7 Subjects
- ... Expression of the brain-derived neurotrophic factor (BDNF) is under tight regulation to accommodate its intricate roles in controlling brain function. Transcription of BDNF initiates from multiple promoters in response to distinct stimulation cues. However, regardless which promoter is used, all BDNF transcripts are processed at two alternative polyadenylation sites, generating two pools of mRNAs ...
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