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- Hoshii, Takayuki, et al. Show all 20 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2009 v.106 no.40 pp. 17163-17168
- brain; fluorescence; hepatocyte growth factor receptor; mice; models; neoplasm cells; neoplasms; stem cells
- ... Controversy remains over whether the cancer stem cell (CSC) theory applies to all tumors. To determine whether cells within a highly aggressive solid tumor are stochastically or hierarchically organized, we combined a reporter system where the nucleostemin (NS) promoter drives GFP expression (termed NS-GFP) with a mouse brain tumor model induced by retroviral Ras expression on a p16Ink⁴a/p19Arf-de ...
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