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- Heuts, Frank, et al. Show all 12 Authors
- Infection and immunity 2009 v.77 no.7 pp. 2908-2918
- Listeria monocytogenes; T-lymphocytes; astrocytes; bone marrow; brain; chimerism; dendritic cells; fibroblasts; gene expression regulation; intravenous injection; macrophages; messenger RNA; mice; microbial growth; microbial load; monocytes; neutrophils; nitric oxide; peritoneum
- ... We analyzed the defensive role of the cytosolic innate recognition receptor nucleotide oligomerization domain 1 (NOD1) during infection with Listeria monocytogenes. Mice lacking NOD1 showed increased susceptibility to systemic intraperitoneal and intravenous infection with high or low doses of L. monocytogenes, as measured by the bacterial load and survival. NOD1 also controlled dissemination of L ...
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