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- Rutherford, Mark S., et al. Show all 5 Authors
- Infection and immunity 2008 v.76 no.8 pp. 3784-3792
- Cryptosporidium parvum; apoptosis; caspase-2; epithelial cells; gene expression; gene expression regulation; genes; humans; intestinal mucosa; parasites; proteins; ribosomal RNA
- ... Cryptosporidium parvum is an obligate intracellular protozoan capable of causing severe diarrheal disease in a wide variety of mammals, including humans. C. parvum infection has been associated with induction of apoptosis in exposed epithelial cells, and we now demonstrate that apoptosis is restricted to a subset of cells actively infected with C. parvum. Approximately 20% of the infected cells un ...
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