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- Hu, Jing; Gao, Jian-Bo; Cao, Yinhe; Bottinger, Erwin; Zhang, Weijia
- Nucleic acids research 2007 v.35 no.5 pp. e35
- normal distribution, etc ; DNA; algorithms; bacterial artificial chromosomes; chromosome aberrations; methodology; neoplasms; pathogenesis; Show all 8 Subjects
- ... Developing effective methods for analyzing array-CGH data to detect chromosomal aberrations is very important for the diagnosis of pathogenesis of cancer and other diseases. Current analysis methods, being largely based on smoothing and/or segmentation, are not quite capable of detecting both the aberration regions and the boundary break points very accurately. Furthermore, when evaluating the acc ...
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