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- Sarafian, Victoria S.; Marinova, Tsvetana T.
- Acta biologica Hungarica 2006 v.57 no.3 pp. 315-322
- autophagy, etc ; apoptosis; epithelial cells; gene expression regulation; glycoproteins; humans; immunohistochemistry; lymphocytes; lysosomes; macrophages; models; quantitative analysis; thymus gland; Show all 13 Subjects
- ... The lysosomal membrane-associated glycoproteins LAMP-1 and LAMP-2 are the major constituents of lysosomal membranes with still undefined biological functions. As autophagy is an alternative model of programmed cell death in which lysosomes play a crucial role, we hypothesize that LAMPs might participate in this phenomenon in the involuting thymus. Thymic glands from cases with acute (infection ind ...
- Teixeira, Miguel Cacho; Fernandes, Alexandra Ramos; Mira, Nuno Pereira; Becker, Jörg Dieter; Sá-Correia, Isabel
- FEMS yeast research 2006 v.6 no.2 pp. 230-248
- autophagy, etc ; 2,4-D; Saccharomyces cerevisiae; carbon; cell division; cell walls; databases; fatty acids; gene expression; gene expression regulation; genes; mathematical models; metabolism; microarray technology; multiple drug resistance; nitrogen; oxidative stress; protective effect; proteins; stress response; transcription (genetics); transcription factors; translation (genetics); yeasts; Show all 24 Subjects
- ... The global gene transcription pattern of the eukaryotic experimental model Saccharomyces cerevisiae in response to sudden aggression with the widely used herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) was analysed. Under acute stress, 14% of the yeast transcripts suffered a greater than twofold change. The yeastract database was used to predict the transcription factors mediating the response re ...