U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication Year 2020 Remove constraint Publication Year: 2020 Subject curcumin Remove constraint Subject: curcumin Subject term ceramides Remove constraint Subject term: ceramides Subject term Curcuma longa Remove constraint Subject term: Curcuma longa Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
Start Over

Search

1  Search Results

1 entry found
Number of results to display per page

Search Results

1. Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis

Author:
David García-Seisdedos; Bohdan Babiy; Milagros Lerma; María E. Casado; Javier Martínez-Botas; Miguel A. Lasunción; Óscar Pastor; Rebeca Busto
Source:
Biochimica et biophysica acta 2020 v.1865 no.5 pp. 158638
ISSN:
1388-1981
Subject:
Curcuma longa; animal models; ceramides; curcumin; enzyme inhibitors; exosomes; fumonisin B1; hydrophobicity; mice; neuroglia; polyphenols; rhizomes; secretion; serine C-palmitoyltransferase; sphingosine N-acyltransferase
Abstract:
... Curcumin, a hydrophobic polyphenol found in the rhizome of Curcuma longa, has been shown to reduce intracellular lipid accumulation in mouse models of lysosomal storage diseases such as Niemann-Pick type C. Exosomes are small extracellular vesicles secreted by cells in response to changes in intracellular ceramide composition. Curcumin can induce exosome/microvesicle release in cellular models of ...
DOI:
10.1016/j.bbalip.2020.158638