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You searched for: Publication Year 2020 Remove constraint Publication Year: 2020 Subject term antibiotics Remove constraint Subject term: antibiotics
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1. The (p)ppGpp-mediated stringent response regulatory system globally inhibits primary metabolism and activates secondary metabolism in Pseudomonas protegens H78

Author:
Lingyu Wu; Zheng Wang; Yejun Guan; Xianqing Huang; Huimin Shi; Yujie Liu; Xuehong Zhang
Source:
Applied microbiology and biotechnology 2020 v.104 no.7 pp. 3061-3079
ISSN:
0175-7598
Subject:
DNA replication; Pseudomonas protegens; amino acid metabolism; antibiotic resistance; antibiotics; bacteria; bacterial growth; biosynthesis; carbohydrates; cell viability; energy metabolism; gene expression; gene expression regulation; guanosine; iron; multigene family; mutation; nutrient content; secondary metabolites; secretion; starvation; stress response; survival rate; transcription (genetics); transcriptomics; translation (genetics)
Abstract:
... Pseudomonas protegens H78 produces multiple secondary metabolites, including antibiotics and iron carriers. The guanosine pentaphosphate or tetraphosphate ((p)ppGpp)-mediated stringent response is utilized by bacteria to survive during nutritional starvation and other stresses. RelA/SpoT homologues are responsible for the biosynthesis and degradation of the alarmone (p)ppGpp. Here, we investigated ...
DOI:
10.1007/s00253-020-10421-5

2. 217 Induction and differentiation of porcine induced pluripotent stem cells into neuronal precursor cell-like cells

Author:
L. S. Machado; N. C. G. Pieri; R. C. Botigelli; R. V. G. Castro; A. F. de Souza; M. A. de Lima; A. Bridi; A. F. C. Andrade; F. V. Meirelles; K. K. Freude; F. F. Bressan
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 236-237
ISSN:
1031-3613
Subject:
Parkinson disease; alkaline phosphatase; animal models; antibiotics; autism; beta-mercaptoethanol; blood serum; cytoplasm; epidermal growth factor; extracellular matrix; fibroblast growth factor 2; fibroblasts; flow cytometry; fluorescent antibody technique; genes; genetic disorders; glutamine; human diseases; humans; induced pluripotent stem cells; medicine; neurons; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; schizophrenia; swine; translational medical research; tubulin; vimentin
Abstract:
... The invitro cellular induction into pluripotency [induced pluripotent stem cell (iPSC) generation] has much evolved since its first report and may play a central role in veterinary regenerative medicine. In particular, the generation of invitro neural precursor cells (NPCs) enabled the creation of models for human genetic diseases, such as autism, schizophrenia, and Parkinson disease. The swine mo ...
DOI:
10.1071/RDv32n2Ab217

3. 220 Exploring the use of mesenchymal stem cells for treatment of mastitis and metritis in cattle

Author:
R. Singh; S. Saini; S. Ansari; S. Jamwal; D. Malakar
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 238
ISSN:
1031-3613
Subject:
adipose tissue; agitation; alkaline phosphatase; animal models; antibiotics; antimicrobial peptides; blood; blood sampling; bovine mastitis; collagenase; cows; culture flasks; cytokines; endometritis; gene expression; genes; immunocytochemistry; inflammation; intravenous injection; mesenchymal stromal cells; mucus; quantitative polymerase chain reaction; somatic cell count; staining; tissue repair; turbidity; zebu
Abstract:
... The present study was carried out to isolate mesenchymal stem cells (MSCs) from adipose tissue of cattle (Bos indicus), characterise them, and apply them for the treatment of mastitis and metritis in the cow. Cattle MSCs were isolated from adipose tissue near the loin region of cow. Isolated adipose tissue was subjected to enzymatic digestion using 2% collagenase with agitation at regular interval ...
DOI:
10.1071/RDv32n2Ab220

4. 221 Isolation of turkey spermatogonia

Author:
E. K. Tomgorova; A. N. Vetokh; L. A. Volkova; N. A. Volkova; H. V. Ashraf; V. A. Bagirov; N. A. Zinovieva
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 238-239
ISSN:
1031-3613
Subject:
Sertoli cells; adhesion; albumins; antibiotics; antibodies; breeds; cell culture; cell growth; cell lines; collagenase; culture media; epidermal growth factor; epithelium; fetal bovine serum; fibroblast growth factor 2; gene pool; glucose; immunohistochemistry; internal transcribed spacers; leukemia; roosters; spermatogenesis; spermatogonia; staining; statistical analysis; stem cells; swine; trypsin; turkeys
Abstract:
... Across different types of spermatogenic epithelium, researchers have focused on the study and production of spermatogonial stem cells and their use as genetic material for creating gene pool cryobanks of valuable breeds and lines of poultry. The aim of our research was to identify optimal conditions for obtaining and culturing turkey spermatogonia. A series of experiments were carried out to deter ...
DOI:
10.1071/RDv32n2Ab221

5. 3-D DNA nanodevices for on-site sensitive detection of antibiotic residues in food

Author:
Xiaowen Liu; Xia Li; Liping Jia; Guigaung Cheng; David Tai Leong; Qingwang Xue
Source:
Chemical communications 2020 v.56 no.83 pp. 12628-12631
ISSN:
1364-548X
Subject:
DNA; antibiotics; aptasensors; food quality; human health
Abstract:
... Developing convenient and sensitive detection methods for antibiotic residues in food is beneficial for ensuring food quality and human health. The tough challenges that limit the development of sensitive, quantitative, portable, on-the-spot antibiotic detectors are the lack of simple and effective target recognition and signal amplification strategies, and direct digital quantification. Herein, w ...
DOI:
10.1039/d0cc05411a

6. Paenibacillus alvei MP1 as a Producer of the Proteinaceous Compound with Activity against Important Human Pathogens, Including Staphylococcus aureus and Listeria monocytogenes

Author:
Magdalena Pajor; Zirui Ray Xiong; Randy W. Worobo; Piotr Szweda
Source:
Pathogens 2020 v.9 no.5 pp. -
ISSN:
2076-0817
Subject:
Escherichia coli; Gram-negative bacteria; Listeria monocytogenes; Paenibacillus alvei; Staphylococcus aureus; ammonium sulfate; animal pathogens; antibiotic resistance; antibiotics; antimicrobial properties; buckwheat honey; heat stability; heat treatment; mass spectrometry; metabolites; peptides; proteinases; research; virulent strains
Abstract:
... An emerging need for new classes of antibiotics is, on the one hand, evident as antimicrobial resistance continues to rise. On the other hand, the awareness of the pros and cons of chemically synthesized compounds’ extensive use leads to a search for new metabolites in already known reservoirs. Previous research showed that Paenibacillus strain (P. alvei MP1) recovered from a b ...
DOI:
10.3390/pathogens9050319

7. The ATP-Binding Cassette (ABC) Transport Systems in Mycobacterium tuberculosis: Structure, Function, and Possible Targets for Therapeutics

Author:
Marcelo Cassio Barreto de Oliveira; Andrea Balan
Source:
Biology 2020 v.9 no.12 pp. -
ISSN:
2079-7737
Subject:
ABC transporters; Mycobacterium tuberculosis; antibiotics; biogeochemical cycles; environment; etiological agents; human diseases; immune response; infection; multiple drug resistance; nutrition; pathogenesis; people; physiology; plasticity; strains; therapeutics; tuberculosis; virulence
Abstract:
... Mycobacterium tuberculosis is the etiological agent of tuberculosis (TB), a disease that affects millions of people in the world and that is associated with several human diseases. The bacillus is highly adapted to infect and survive inside the host, mainly because of its cellular envelope plasticity, which can be modulated to adapt to an unfriendly host environment; to manipulate the host immune ...
DOI:
10.3390/biology9120443

8. Abundance, Diversity and Role of ICEs and IMEs in the Adaptation of Streptococcus salivarius to the Environment

Author:
Julie Lao; Gérard Guédon; Thomas Lacroix; Florence Charron-Bourgoin; Virginie Libante; Valentin Loux; Hélène Chiapello; Sophie Payot; Nathalie Leblond-Bourget
Source:
Genes 2020 v.11 no.9 pp. -
ISSN:
2073-4425
Subject:
Streptococcus salivarius; antibiotics; biochemical pathways; genes; genetic variation; horizontal gene transfer; humans; microbiome; pharynx; toxic substances
Abstract:
... Streptococcus salivarius is a significant contributor to the human oral, pharyngeal and gut microbiomes that contribute to the maintenance of health. The high genomic diversity observed in this species is mainly caused by horizontal gene transfer. This work aimed to evaluate the contribution of integrative and conjugative elements (ICEs) and integrative and mobilizable elements (IMEs) in S. saliva ...
DOI:
10.3390/genes11090999

9. Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB

Author:
Bryce P. Johnson; Erin M. Scull; Dustin A. Dimas; Tejaswi Bavineni; Chandrasekhar Bandari; Andrea L. Batchev; Eric D. Gardner; Susan L. Nimmo; Shanteri Singh
Source:
Applied microbiology and biotechnology 2020 v.104 no.10 pp. 4383-4395
ISSN:
0175-7598
Subject:
alkylation; antibiotics; biocatalysis; biocatalysts; cannabinoids; dimethylallyltranstransferase; drugs; regioselectivity
Abstract:
... Aromatic prenyltransferases are known for their extensive promiscuity toward aromatic acceptor substrates and their ability to form various carbon-carbon and carbon-heteroatom bonds. Of particular interest among the prenyltransferases is NphB, whose ability to geranylate cannabinoid precursors has been utilized in several in vivo and in vitro systems. It has therefore been established that prenylt ...
DOI:
10.1007/s00253-020-10529-8
PubMed:
32189045
PubMed Central:
PMC7190591

10. Accumulation characteristics and biological response of ginger to sulfamethoxazole and ofloxacin

Author:
Yao Lv; Jiamin Xu; Kun Xu; Xiaohui Liu; Xiaochun Guo; Shaoyong Lu; Beidou Xi
Source:
Environmental pollution 2020 v.262 pp. 114203
ISSN:
0269-7491
Subject:
Zingiber officinale; antibiotics; antioxidant enzymes; catalase; energy; enzyme activity; food chain; ginger; human health; hydrogen peroxide; maximum residue limits; ofloxacin; peroxidase; pollution; resistance genes; rhizomes; risk; root growth; roots; sulfamethoxazole; superoxide anion; superoxide dismutase
Abstract:
... The potential risk to human health of antibiotics that pass through the food chain has become an important global issue, but there are few reports on the response of ginger (Zingiber officinale) to antibiotic pollution. In this study, we investigated the enrichment characteristics and biological response of ginger to sulfamethoxazole (SMZ) and ofloxacin (OFL) residues, which are common in the envi ...
DOI:
10.1016/j.envpol.2020.114203

11. Achieving simultaneous nitrogen and antibiotic removal in one-stage partial nitritation-Anammox (PN/A) process

Author:
Huayu Li; Hong Yao; Tao Liu; Bingzheng Wang; Jun Xia; Jianhua Guo
Source:
Environment international 2020 v.143 pp. 105987
ISSN:
0160-4120
Subject:
Escherichia coli; anaerobic ammonium oxidation; antibiotics; environment; genes; nitrogen; sulfadiazine; total nitrogen; wastewater; wastewater treatment; water pollution
Abstract:
... Partial nitritation-Anammox (PN/A) process has been recognized as a sustainable process for biological nitrogen removal. Although various antibiotics have been ubiquitously detected in influent of wastewater treatment plants, little is known whether functional microorganisms in the PN/A process are capable of biodegrading antibiotics. This study aimed to investigate simultaneous nitrogen and antib ...
DOI:
10.1016/j.envint.2020.105987

12. Acibenzolar-S-methyl activates stomatal-based defense against Pseudomonas cannabina pv. alisalensis in cabbage

Author:
Takako Ishiga; Yumi Iida; Nanami Sakata; Tsutomu Ugajin; Tetsuya Hirata; Shizuku Taniguchi; Keisuke Hayashi; Yasuhiro Ishiga
Source:
Journal of general plant pathology 2020 v.86 no.1 pp. 48-54
ISSN:
1345-2630
Subject:
Brassica oleracea; Pseudomonas; acibenzolar-S-methyl; antibiotics; blight; cabbage; copper; disease control; genetic markers; pathogens; soil drenching; systemic acquired resistance; Japan
Abstract:
... Pseudomonas cannabina pv. alisalensis (Pcal), which causes bacterial blight of brassicaceous plants, is an economically important pathogen worldwide. Copper fungicide and antibiotics are major strategies to manage the disease caused by Pcal; however, a Pcal strain resistant to these chemicals has already been found, and severe outbreaks of bacterial blight have been reported on cabbage in Japan. T ...
DOI:
10.1007/s10327-019-00883-5

13. Acidic conditions enhance the removal of sulfonamide antibiotics and antibiotic resistance determinants in swine manure

Author:
Hui Lin; Wanchun Sun; Qiaogang Yu; Junwei Ma
Source:
Environmental pollution 2020 v.263 pp. 114439
ISSN:
0269-7491
Subject:
Firmicutes; Proteobacteria; acidification; animal manure management; antibiotic resistance; antibiotic resistance genes; antibiotics; bacteria; bacterial communities; gene transfer; pH; pig manure
Abstract:
... Manure pH may vary depending on its inherent composition or additive contents. However, the effect of pH on the fate of antibiotics and antibiotic resistance determinants in manure remains unclear. This work demonstrated that pH adjustment promoted the removal of different sulfonamide antibiotics (SAs) within swine manure under incubation conditions, which increased from 26–60.8% to 75.0–86.0% by ...
DOI:
10.1016/j.envpol.2020.114439

14. Acrophiarin (antibiotic S31794/F‐1) from Penicillium arenicola shares biosynthetic features with both Aspergillus‐ and Leotiomycete‐type echinocandins

Author:
Nan Lan; Bruno Perlatti; Daniel J. Kvitek; Philipp Wiemann; Colin J. B. Harvey; Jens Frisvad; Zhiqiang An; Gerald F. Bills
Source:
Environmental microbiology 2020 v.22 no.6 pp. 2292-2311
ISSN:
1462-2912
Subject:
Aspergillus; Penicillium; antibiotics; biosynthesis; echinocandins; glutamine; horizontal gene transfer; hydroxylation; iron; lipopeptides; multigene family; phylogeny; serine; threonine
Abstract:
... The antifungal echinocandin lipopeptide, acrophiarin, was circumscribed in a patent in 1979. We confirmed that the producing strain NRRL 8095 is Penicillium arenicola and other strains of P. arenicola produced acrophiarin and acrophiarin analogues. Genome sequencing of NRRL 8095 identified the acrophiarin gene cluster. Penicillium arenicola and echinocandin‐producing Aspergillus species belong to ...
DOI:
10.1111/1462-2920.15004

15. Actinotignum schaalii Abscess in a Patient with Common Variable Immunodeficiency

Author:
Christine Marie Panganiban; Sudhir Gupta
Source:
Pathogens 2020 v.9 no.6 pp. -
ISSN:
2076-0817
Subject:
abscess; antibiotics; cellulitis; drainage; elderly; immunosuppression; infection; pathogens; patients; urinary tract diseases
Abstract:
... Actinotignum schaalii is an anaerobic, gram-positive commensal organism of the urogenital tract. A. schaalii typically causes urinary tract infections, predominantly in the elderly. Here, we describe the first case of A. schaalii infection presenting as cellulitis and abscess in a patient with common variable immunodeficiency. The patient was successfully treated with an incision and drainage and ...
DOI:
10.3390/pathogens9060494

16. Activation of persulfate by biochar from spent malt rootlets for the degradation of trimethoprim in the presence of inorganic ions

Author:
Eleni Grilla; John Vakros; Ioannis Konstantinou; Ioannis D Manariotis; Dionissios Mantzavinos
Source:
Journal of chemical technology and biotechnology 2020 v.95 no.9 pp. 2348-2358
ISSN:
0268-2575
Subject:
antibiotics; aromatic compounds; biochar; biotechnology; carbon; catalysts; degradation; electron transfer; free radicals; hydroxylation; inorganic ions; malt; occurrence; organic matter; oxidation; pH; pollutants; sodium; solar radiation; sulfates; surface area; trimethoprim; ultrasonics; wastewater; water; water quality
Abstract:
... BACKGROUND: Antibiotics such as trimethoprim (TMP) are used in large quantities and recent studies show that TMP is not eliminated completely in wastewater from municipal treatment plants. Advanced oxidation processes (AOPs), especially sulfate radical‐based AOPs, are highly reactive in the presence of a catalyst. Biochar, a green and low‐cost carbon material, is an excellent catalyst to degrade p ...
DOI:
10.1002/jctb.6513

17. Active delivery of antimicrobial nanoparticles into microbial cells through surface functionalization strategies

Author:
Akbar Bahrami; Rana Delshadi; Seid Mahdi Jafari
Source:
Trends in food science & technology 2020 v.99 pp. 217-228
ISSN:
0924-2244
Subject:
active ingredients; antibiotics; antimicrobial properties; bacteria; behavior change; biochemical compounds; ligands; nanoparticles; polymers; public health; synergism
Abstract:
... Recently, the structural and behavioral changes of microorganisms have been rapidly increased. The appearance of resistant bacteria by enhancing antibiotic adaptation potentially is a significant concern for public health; thus, many efforts are needed to promote efficiency of antimicrobial substances. Surface functionalization of antimicrobial nanoparticles can improve their efficiency and divers ...
DOI:
10.1016/j.tifs.2020.03.008

18. Active packaging film containing oregano essential oil microcapsules and their application for strawberry preservation

Author:
Li Li; Wenlong Song; Chunhua Shen; Qingfeng Dong; Yifen Wang; Sheng Zuo
Source:
Journal of food processing and preservation 2020 v.44 no.10 pp. e14799
ISSN:
0145-8892
Subject:
acetates; antibiotics; carbon dioxide; cold chain; extrusion; firmness; hydrogen peroxide; income; malondialdehyde; metabolism; nuclear magnetic resonance spectroscopy; oregano oil; oxygen; permeability; polyethylene; shelf life; spoilage; strawberries; titratable acidity; water content
Abstract:
... An active packaging film based on low‐density polyethylene (LDPE)/ethylene‐vinyl acetate (EVA) copolymer was prepared. Oregano essential oil microcapsules were prepared by spray drying and added as active antibacterial ingredients to the LDPE/EVA film by melt blending and extrusion casting and enhanced the moisture permeability and gas permeability of the film. The active packaging film effectivel ...
DOI:
10.1111/jfpp.14799

19. Active pharmaceutical ingredients in Malaysian drinking water: consumption, exposure, and human health risk

Author:
Sze Yee Wee; Didi Erwandi Mohamad Haron; Ahmad Zaharin Aris; Fatimah Md. Yusoff; Sarva Mangala Praveena
Source:
Environmental geochemistry and health 2020 v.42 no.10 pp. 3247-3261
ISSN:
0269-4042
Subject:
antibiotics; anticonvulsants; beta-adrenergic antagonists; caffeine; chloramphenicol; ciprofloxacin; detection limit; dexamethasone; diazinon; diclofenac; geochemistry; human health; liquid chromatography; propranolol; relative risk; risk estimate; solid phase extraction; sulfamethoxazole; surface water; tandem mass spectrometry; tap water; therapeutics; triclosan; water quality; water supply; Malaysia
Abstract:
... Active pharmaceutical ingredients (APIs) are typical endocrine disruptors found in common pharmaceuticals and personal care products, which are frequently detected in aquatic environments, especially surface water treated for drinking. However, current treatment technologies are inefficient for removing emerging endocrine disruptors, leading to the potential contamination of tap water. This study ...
DOI:
10.1007/s10653-020-00565-8

20. Activity-directed expansion of a series of antibacterial agents

Author:
Abbie Leggott; Justin E. Clarke; Shiao Chow; Stuart L. Warriner; Alex J. O’Neill; Adam Nelson
Source:
Chemical communications 2020 v.56 no.58 pp. 8047-8050
ISSN:
1364-548X
Subject:
Staphylococcus aureus; antibiotics; catalytic activity; chemical reactions; palladium
Abstract:
... The feasibility of using activity-directed synthesis to drive antibacterial discovery was investigated. An array of 220 Pd-catalysed microscale reactions was executed, and the crude product mixtures were evaluated for activity against Staphylococcus aureus. Scale-up of the hit reactions, purification and evaluation, enabled expansion of a class of antibacterial quinazolinones. The novel antibacter ...
DOI:
10.1039/d0cc02361b

21. Acute Toxicity and Risk Assessment of Florfenicol for Nile Tilapia Larvae

Author:
Cristiano Campos Mattioli; Bruna Milke Chiste; Natalia Akemi Takeshita; Claudio Martin Jonsson; Vera Lucia Ferracini; Hamilton Hisano
Source:
Bulletin of environmental contamination and toxicology 2020 v.105 no.5 pp. 721-727
ISSN:
0007-4861
Subject:
Oreochromis niloticus; acute toxicity; antibiotics; biometry; dissolved oxygen; exposure duration; florfenicol; lethal concentration 50; pH; pollution; risk; risk assessment; solvents; weight loss
Abstract:
... The aim of this study was to determine the median lethal concentration (LC₅₀₋₉₆ₕ), effective concentration (EC₅₀₋₉₆ₕ), risk assessment, and development of Nile tilapia Oreochromis niloticus larvae submitted to florfenicol (FF) exposure. Fish (n = 147; 8.6 ± 0.6 mg; 7 fish/aquarium) were randomly distributed in 21 aquaria (1 L) and exposed to five concentrations of FF 58.73; 131.31; 198.96; 241.88 ...
DOI:
10.1007/s00128-020-03013-6

22. Acute Toxicity, Bioaccumulation, and Bioreduction of Two Antibiotics, Norfloxacin and Ofloxacin, in the Snail Bellamya aeruginosa

Author:
Shuwen He; Qinyu Sun; Yu Liu; Ling Li; Xiangfei Yang
Source:
Water, air, and soil pollution 2020 v.231 no.3 pp. 96
ISSN:
0049-6979
Subject:
Bellamya aeruginosa; acute toxicity; adults; antibiotics; aquatic animals; benthic organisms; bioaccumulation factor; depuration; maximum residue limits; median effective concentration; norfloxacin; ofloxacin; risk; sediments; snails; subchronic exposure
Abstract:
... Fluoroquinolones (FQs) present in water environments pose threats to aquatic organisms. The concentration of FQs adsorbed onto sediments is generally higher than that in water. Here, we studied the toxicities of two FQ antibiotics, norfloxacin (NOR) and ofloxacin (OFL), on the snail Bellamya aeruginosa, an adaptable benthic animal. For this, we performed acute toxicity experiments on young snails ...
DOI:
10.1007/s11270-020-4458-5

23. Acute and long-term effects of antibiotics commonly used in laboratory animal medicine on the fecal microbiota

Author:
Scott W. Korte; Rebecca A. Dorfmeyer; Craig L. Franklin; Aaron C. Ericsson
Source:
Veterinary research 2020 v.51 no.1 pp. 116
ISSN:
1297-9716
Subject:
antibiotics; biomedical research; dermatitis; enrofloxacin; experimental design; feces; intestinal microorganisms; laboratory animals; medicine; mice; ointments; taxonomy; veterinary medicine
Abstract:
... Biomedical research relies on the use of animal models, and the animals used in those models receive medical care, including antibiotics for brief periods of time to treat conditions such as dermatitis, fight wounds, and suspected bacterial pathogens of unknown etiology. As many mouse model phenotypes are sensitive to changes in the gut microbiota, our goal was to examine the effect of antibiotics ...
DOI:
10.1186/s13567-020-00839-0

24. Adding monoglycerides containing short and medium chain fatty acids to milk replacer: effects on health and performance of preweaned calves

Author:
Federico Righi; Marica Simoni; Carla Bresciani; Clotilde Silvia Cabassi; Sara Flisi; Mikenzie England Hanlon; Andrea Sala; Costanza Spadini; Massimiliano Festuccia; Giorgio Morini; Ferdinando Gazza; Luisa Ragionieri; Afro Quarantelli
Source:
Italian journal of animal science 2020 v.19 no.1 pp. 1417-1427
ISSN:
1828-051X
Subject:
Holstein; antibacterial properties; antibiotics; biometry; blood serum; body weight; calves; digestive tract; enteropathogens; feed conversion; health status; liquids; males; milk replacer; monoacylglycerols; therapeutics
Abstract:
... The aim of this trial was to investigate the effects of a blend of monoglycerides of short- and medium-chain fatty acids (SMCFA) on health status and growth of preweaned male calves from 16 to 72 days of age. The in vivo study was conducted as a complete randomised block design. Twenty Italian Holstein calves received starter administered ad libitum and 6 L of milk replacer/day (12% powder concent ...
DOI:
10.1080/1828051X.2020.1847208

25. Additives affect the distribution of metabolic profile, microbial communities and antibiotic resistance genes in high-moisture sweet corn kernel silage

Author:
Zhe Wu; Yingning Luo; Jinze Bao; Ying Luo; Zhu Yu
Source:
Bioresource technology 2020 v.315 pp. 123821
ISSN:
0960-8524
Subject:
Ascomycota; Lactobacillus brevis; Lactobacillus plantarum; Proteobacteria; antibiotic resistance; antibiotics; corn; lactic acid; metabolites; metabolome; protein degradation; seeds; silage; sweetcorn; technology; vanillin; viruses
Abstract:
... This work investigated the effects of chemical additive vanillin (V), homofermentative Lactobacillus plantarum (LP), and heterofermentative Lactobacillus brevis (LB) on the distribution of the metabolome, microbial communities, viruses, and antibiotic-resistance genes in high-moisture corn kernel silage. LP and LB improved lactic acid production, whereas V and LB inhibited protein degradation. A s ...
DOI:
10.1016/j.biortech.2020.123821

26. Adhesion and invasion of Campylobacter jejuni in chickens with a modified gut microbiota due to antibiotic treatment

Author:
Zifeng Han; Li Li; Thomas Willer; Wolfgang Baumgärtner; Silke Rautenschlein
Source:
Veterinary microbiology 2020 v.240 pp. 108504
ISSN:
0378-1135
Subject:
Campylobacter jejuni; antibiotics; chickens; food chain; foodborne illness; histopathology; human diseases; intestinal microorganisms; liver; mucosa; risk; signs and symptoms (animals and humans); spleen
Abstract:
... Campylobacter jejuni (C. jejuni) is a predominant cause of foodborne illness in humans, while its colonization in chickens is usually asymptomatic. Antibiotics are not routinely used to treat chickens against C. jejuni, but in the face of other bacterial diseases, C. jejuni may be exposed to antibiotics. In this study, chickens were treated with antibiotics (AT) to modify the gut microbiota compos ...
DOI:
10.1016/j.vetmic.2019.108504

27. Adipostatins E-J, new potent antimicrobials identified as inhibitors of coenzyme-A biosynthesis

Author:
Lyanne Gómez-Rodríguez; Pamela J. Schultz; Giselle Tamayo-Castillo; Garry D. Dotson; David H. Sherman; Ashootosh Tripathi
Source:
Tetrahedron letters 2020 v.61 no.5 pp. 151469
ISSN:
0040-4039
Subject:
Streptomyces; antibiotics; bacteria; biosynthesis; chemical reactions; chemical structure; coenzyme A; cysteamine; drugs; enzymes; inhibitory concentration 50; virulent strains
Abstract:
... Phosphopantetheine is a key structural element in biological acyl transfer reactions found embedded within coenzyme A (CoA). Phosphopantothenoylcysteine synthetase (PPCS) is responsible for installing a cysteamine group within phosphopantetheine. Therefore, it holds considerable potential as a drug target for developing new antimicrobials. In this study, we adapted a biochemical assay specific for ...
DOI:
10.1016/j.tetlet.2019.151469

28. Administration of Bacillus cultures as direct-fed microorganisms improves growth performance and reduces mortality of broilers raised under performance-reducing stress challenge

Author:
C.A. Johnson; T. Duong; K.A. Smith; N.R. Augspurger; J.T. Lee
Source:
Journal of applied poultry research 2020 v.29 no.4 pp. 798-807
ISSN:
1056-6171
Subject:
Bacillus (bacteria); antibiotics; broiler chickens; disease and pest management; dose response; growth performance; growth promotion; microorganisms; mortality; poultry diseases; poultry production; rearing
Abstract:
... The use of direct-fed microorganisms (DFM) is an important alternative to antibiotic growth promoters (AGP) for improving growth and managing disease in poultry production. We investigated the administration of 2 multistrain Bacillus cultures administered as DFM on growth performance and mortality of broiler chickens reared under performance-reducing stress challenge. The first experiment evaluate ...
DOI:
10.1016/j.japr.2020.07.002

29. Administration of a Nutraceutical Mixture Composed by Aloe arborescens, Annona muricata, Morinda citrifolia, Beta rubra, Scutellaria baicalensis, and Vaccinium myrtillus Reduces Doxorubicin-Induced Side Effects

Author:
Natasha Irrera; Giovanni Pallio; Federica Mannino; Rosario Gugliotta; Daniela Metro; Domenica Altavilla; Francesco Squadrito
Source:
Nutrition and cancer 2020 v.72 no.2 pp. 343-351
ISSN:
1532-7914
Subject:
Aloe arborescens; Annona muricata; Morinda citrifolia; Scutellaria baicalensis; Vaccinium myrtillus; adverse effects; anti-inflammatory activity; antibiotics; antioxidants; blood; body weight; dietary supplements; doxorubicin; drug therapy; food intake; heart; liver; oxidative stress; patients; protective effect; quality of life; rats; toxicity
Abstract:
... The antibiotic doxorubicin is often used as an anti-neoplastic drug; however, many patients showed very unpleasant side-effects. Previous studies have demonstrated that dietary substances such as Aloe arborescens, Annona muricata, Morinda citrifolia, Beta rubra, Scutellaria baicalensis, and Vaccinium myrtillus may have anti-oxidant, anti-proliferative, and anti-inflammatory effects. The purpose of ...
DOI:
10.1080/01635581.2019.1633364

30. Administration of direct-fed Bacillus cultures and refined functional carbohydrates to broiler chickens improves growth performance and promotes positive shifts in gastrointestinal microbiota

Author:
L.K. Froebel; S. Jalukar; T.A. Lavergne; C.D. Coufal; T. Duong
Source:
Journal of applied poultry research 2020 v.29 no.4 pp. 765-774
ISSN:
1056-6171
Subject:
Bacillus (bacteria); Campylobacter; Saccharomyces; antibiotics; growth performance; humans; intestinal microorganisms; lactic acid; poultry production; prebiotics; research
Abstract:
... Due to regulation and consumer-driven decreases in the use of antibiotics, there is a critical need for the development of alternatives to antibiotic growth promoters (AGP) for use in poultry production. Direct-fed microorganisms (DFM) and prebiotics, which have been demonstrated to improve growth performance and microbial safety of poultry, are thought to be potentially important alternatives to ...
DOI:
10.1016/j.japr.2020.06.004

31. Adsorption Characteristics of Synthesized Polyelectrolytes onto Alumina Nanoparticles and their Application in Antibiotic Removal

Author:
Thi-Huong Dao; Thi-Quynh-Mai Vu; Ngoc-Trung Nguyen; Thu-Thao Pham; Thi-Lien Nguyen; Shin-ichi Yusa; Tien-Duc Pham
Source:
Langmuir 2020 v.36 no.43 pp. 13001-13011
ISSN:
1520-5827
Subject:
Fourier transform infrared spectroscopy; adsorption; aluminum oxide; antibiotics; ciprofloxacin; electrolytes; gel chromatography; hospitals; models; nuclear magnetic resonance spectroscopy; pH; sulfonic acids; wastewater
Abstract:
... The present study aims to investigate the adsorption of synthesized poly(2-acrylamide-2-methylpropane sulfonic acid) (PAMPs) onto alumina nanoparticles and their application in the removal of ciprofloxacin (CFX) antibiotic from a water environment. The PAMPs were successfully synthesized and characterized by nuclear magnetic resonance and gel-permeation chromatography methods. The number- and weig ...
DOI:
10.1021/acs.langmuir.0c02352

32. Adsorption and desorption behaviors of antibiotic ciprofloxacin on functionalized spherical MCM-41 for water treatment

Author:
Dongwei Lu; Shu Xu; Wei Qiu; Yan Sun; Xianbin Liu; Jingjing Yang; Jun Ma
Source:
Journal of cleaner production 2020 v.264 pp. 121644
ISSN:
0959-6526
Subject:
absorbents; adsorbents; adsorption; antibiotics; ciprofloxacin; desorption; models; porous media; silica; sorption isotherms; water treatment
Abstract:
... Extensively used antibiotic ciprofloxacin increases in water environment, which is not efficiently removed by means of conventional adsorbents. MCM-41 has great potential for ciprofloxacin removal. There has been little research on ciprofloxacin removal by MCM-41 and their corresponding adsorption/desorption behaviors. In this study, amorphous SiO₂, MCM-41 and diamine-functionalized MCM-41 were us ...
DOI:
10.1016/j.jclepro.2020.121644

33. Adsorption of Sulfonamide Antibiotic onto Activated Carbon Prepared from an Agro-industrial By-Product as Low-Cost Adsorbent: Equilibrium, Thermodynamic, and Kinetic Studies

Author:
Sibel Aslan; Meltem Şirazi
Source:
Water, air, and soil pollution 2020 v.231 no.5 pp. 222
ISSN:
0049-6979
Subject:
activated carbon; adsorbents; adsorption; agroindustrial byproducts; air; antibiotics; heat production; models; olive oil; olive pomace; pH; phytotoxicity; porosity; soil pollution; sorption isotherms; sulfadiazine; surface area; temperature; wastes; water
Abstract:
... Olive pomace (OP) is an agricultural by-product of the olive oil production process. Olive oil mills generate a huge amount of OP that has adverse impacts on the environment due to its phytotoxic properties. Therefore, the utilization of OP in the production of activated carbon may be considered as an alternative eco-friendly solution for disposal and recycling of this waste. The adsorption of sul ...
DOI:
10.1007/s11270-020-04576-0

34. Adsorption/desorption of sulfamethoxypyridazine and enrofloxacin in agricultural soils

Author:
C. Álvarez-Esmorís; M. Conde-Cid; G. Ferreira-Coelho; M.J. Fernández-Sanjurjo; A. Núñez-Delgado; E. Álvarez-Rodríguez; M. Arias-Estévez
Source:
Science of the total environment 2020 v.706 pp. 136015
ISSN:
0048-9697
Subject:
adsorption; agricultural soils; antibiotics; desorption; enrofloxacin; equations; exchangeable magnesium; nitrogen content; public health; regression analysis; risk; soil organic carbon; soil pollution; sorption isotherms; variance; vines
Abstract:
... Adsorption and desorption processes were studied for the antibiotics sulfamethoxypyridazine (SMP) and enrofloxacin (ENR) in 20 agricultural soils devoted to wheat-potato and vine cultivation. Batch experiments were used to conduct kinetic studies, as well as to evaluate adsorption and desorption for different concentrations of antibiotics. The results indicated that adsorption curves were linear f ...
DOI:
10.1016/j.scitotenv.2019.136015

35. Adsorptive interaction of antibiotic ciprofloxacin on polyethylene microplastics: Implications for vector transport in water

Author:
Thilakshani Atugoda; Hasintha Wijesekara; D.R.I.B. Werellagama; K.B.S.N. Jinadasa; Nanthi S. Bolan; Meththika Vithanage
Source:
Environmental technology & innovation 2020 v.19 pp. 100971
ISSN:
2352-1864
Subject:
adsorption; antibiotics; aquatic environment; ciprofloxacin; dissolved organic matter; environmental technology; humic acids; hydrophobicity; ionic strength; microplastics; models; pH; polyethylene; sorption isotherms
Abstract:
... This study investigates the adsorption behavior of Ciprofloxacin (CPX) antibiotic on polyethylene (PE) microplastics through batch adsorption experiments under various environmental conditions, i.e., ionic strengths, pH and in the presence of dissolved organic matter (DOM). The adsorption of CPX showed a gradual increase with increasing pH reaching the maximum adsorption at pH 6.5–7.5 and then dec ...
DOI:
10.1016/j.eti.2020.100971

36. Adsorptive removal of veterinary antibiotics from water using an integrated photocatalyst (IPCA)

Author:
Martha N. Chollom; Sudesh Rathilal; Feroz M. Swalaha; Babatunde F Bakare
Source:
International journal of environmental studies 2020 v.77 no.2 pp. 236-254
ISSN:
1029-0400
Subject:
activated carbon; adsorption; antibiotics; half life; pH; photocatalysis; photocatalysts; photolysis; sorption isotherms; titanium dioxide; veterinary drugs
Abstract:
... The synthesising of a novel catalyst known as the integrated photo-catalysts (IPCA) by impregnating activated carbon (AC) with titanium dioxide (TiO₂) particles by ultra-sonication was used. The kinetics of antibiotics removal using adsorption and photodegradation were monitored and modelled. The effects of photocatalyst concentration and solution pH were investigated. Maximum removal percentages ...
DOI:
10.1080/00207233.2020.1723952

37. Advanced engineering of third-generation lysins and formulation strategies for clinical applications

Author:
Vincent De Maesschalck; Diana Gutiérrez; Jan Paeshuyse; Rob Lavigne; Yves Briers
Source:
Critical reviews in microbiology 2020 v.46 no.5 pp. 548-564
ISSN:
1549-7828
Subject:
antibacterial properties; antibiotic resistance; antibiotics; bioavailability; endolysin; half life; peptidoglycans; therapeutics
Abstract:
... One of the possible solutions for the current antibiotic resistance crisis may be found in (often bacteriophage-derived) peptidoglycan hydrolases. The first clinical trials of these natural enzymes, coined here as first-generation lysins, are currently ongoing. Moving beyond natural endolysins with protein engineering established the second generation of lysins. In second-generation lysins, the fo ...
DOI:
10.1080/1040841X.2020.1809346

38. Advances and challenges in metallic nanomaterial synthesis and antibacterial applications

Author:
Zengchao Guo; Yun Chen; Yihan Wang; Hui Jiang; Xuemei Wang
Source:
Journal of materials chemistry B 2020 v.8 no.22 pp. 4764-4777
ISSN:
2050-7518
Subject:
antibacterial properties; antibiotics; bacterial infections; biocompatibility; cytotoxicity; multiple drug resistance; public health
Abstract:
... Multi-drug resistant bacterial infection has become one of the most serious threats to global public health. The preparation and application of new antibacterial materials are of great significance for solving the infection problem of bacteria, especially multi-drug resistant bacteria. The exceptional antibacterial effects of metal nanoparticles based on their unique physical and chemical properti ...
DOI:
10.1039/d0tb00099j

39. Advances in magnetic porous organic frameworks for analysis and adsorption applications

Author:
Qianqian Wang; Tian Gao; Lin Hao; Yaxing Guo; Weihua Liu; Liying Guo; Chun Wang; Zhi Wang; Qiuhua Wu
Source:
Trends in analytical chemistry 2020 v.132 pp. 116048
ISSN:
0165-9936
Subject:
adsorbents; adsorption; analytical chemistry; antibiotics; chemical species; dyes; endocrine-disrupting chemicals; environmental science; extraction; heavy metals; magnetism; methodology; organic compounds; pesticides; porosity; research; researchers; separation; synthesis; toxins
Abstract:
... Developing high-performance magnetic adsorbents is highly desirable for achieving efficient extraction of analytes. As an emerging class of advanced functional materials, magnetic porous organic frameworks (M-POFs) have created tremendous interest among researchers because of their remarkable features such as permanent porosity, diverse synthesis methods, high physicochemical stability, strong mag ...
DOI:
10.1016/j.trac.2020.116048

40. Advances in the application, toxicity and degradation of carbon nanomaterials in environment: A review

Author:
Zan Peng; Xiaojuan Liu; Wei Zhang; Zhuotong Zeng; Zhifeng Liu; Chang Zhang; Yang Liu; Binbin Shao; Qinghua Liang; Wangwang Tang; Xingzhong Yuan
Source:
Environment international 2020 v.134 pp. 105298
ISSN:
0160-4120
Subject:
antibiotics; biodegradation; carbon nanotubes; chemical degradation; energy; enzymes; gases; graphene; heavy metals; humans; mechanical damage; medicine; microorganisms; oxidative stress; physicochemical properties; pollution; pollution control; stress response; toxicity
Abstract:
... Carbon nanomaterials (CNMs) are novel nanomaterials with excellent physicochemical properties, which are widely used in biomedicine, energy and sensing. Besides, CNMs also play an important role in environmental pollution control, which can absorb heavy metals, antibiotics and harmful gases. However, CNMs are inevitably entering the environment while they are rapidly developing. They are harmful t ...
DOI:
10.1016/j.envint.2019.105298

41. Advancing Liquid Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Toward Ultrahigh-Throughput Analysis

Author:
Henriette Krenkel; Evita Hartmane; Cristian Piras; Jeffery Brown; Michael Morris; Rainer Cramer
Source:
Analytical chemistry 2020 v.92 no.4 pp. 2931-2936
ISSN:
1520-6882
Subject:
antibiotics; atmospheric pressure; desorption; high-throughput screening methods; ionization; lipids; liquids; matrix-assisted laser desorption-ionization mass spectrometry; milk; peptides; screening
Abstract:
... Label-free high-throughput screening using mass spectrometry has the potential to provide rapid large-scale sample analysis at a speed of more than one sample per second. Such speed is important for compound library, assay and future clinical screening of millions of samples within a reasonable time frame. Herein, we present a liquid atmospheric pressure matrix-assisted laser desorption/ionization ...
DOI:
10.1021/acs.analchem.9b05202
PubMed:
31967792
PubMed Central:
PMC7145281

42. Advantage of zinc oxide nanoparticles over silver nanoparticles for the management of Aeromonas veronii infection in Xiphophorus hellerii

Author:
Soumya Das; R. Aswani; Sebastian Jose Midhun; E.K. Radhakrishnan; Jyothis Mathew
Source:
Microbial pathogenesis 2020 v.147 pp. 104348
ISSN:
0882-4010
Subject:
Aeromonas veronii; Xiphophorus; antibacterial properties; antibiotic resistance; antibiotics; disease control; fish diseases; fish industry; gills; histology; histopathology; in vivo studies; intestines; lethal dose 50; liver; nanoparticles; nanosilver; ornamental fish; pathogens; silver; survival rate; zinc oxide
Abstract:
... Bacterial pathogens cause significant challenge to the ornamental fish industry. Eventhough antibiotic administration has been recommended to manage fish diseases, there is alarming concern with emergence of antibiotic resistance. This indicates the need for the development of alternative methods with multi-targeted action to manage fish diseases. In the study, silver (AgNPs) and zinc oxide (ZnONP ...
DOI:
10.1016/j.micpath.2020.104348

43. Advantages of Bacillus-based probiotics in poultry production

Author:
U. Ramlucken; R. Lalloo; Y. Roets; G. Moonsamy; C. Jansen van Rensburg; M.S. Thantsha
Source:
Livestock science 2020 v.241 pp. 104215
ISSN:
1871-1413
Subject:
Bacillus (bacteria); absorption; aflatoxins; ammonia; antibiotics; broiler chickens; competitive exclusion; digestion; digestive tract; environmental sustainability; feed conversion; food production; immunomodulation; intestines; meat; mortality; poultry feed; poultry industry; poultry production; probiotics; shelf life; spores; toxicity; viability
Abstract:
... Broiler chicken production is one of the most lucrative food production industries globally because of the demand for poultry products. Stringent regulations pertaining to the use of antibiotic growth promoters (AGP) in livestock production coupled with the changing consumer trends in terms of an increase in the consumtion of AGP-free meat pose a challenge to the poultry industry. Probiotics, spec ...
DOI:
10.1016/j.livsci.2020.104215

44. Aetiology, diagnosis, treatment and outcome of traumatic reticuloperitonitis in cattle

Author:
Ueli Braun; Christian Gerspach; Stefanie Ohlerth; Sonja Warislohner; Karl Nuss
Source:
veterinary journal 2020 v.255 pp. 105424
ISSN:
1090-0233
Subject:
abdomen; anorexia; antibiotics; clinical examination; coagulation; cows; etiology; euthanasia; fever; fibrinogen; foreign bodies; glutaraldehyde; image analysis; inflammation; leukocyte count; magnetic materials; medical treatment; milk production; monitoring; pain; protein content; radiography; reticulum; rumen; surgery; ultrasonography
Abstract:
... Traumatic reticuloperitonitis (TRP) in cattle is caused by ingested nails, pieces of wire, and other nonmetallic materials that injure the reticular wall. Clinical signs of acute TRP may include anorexia, fever, drop in milk production, rumen atony and tympany, abdominal pain, an arched back, a tucked up and “guarded” abdomen and spontaneous grunting, but may be obscure or absent in chronic cases. ...
DOI:
10.1016/j.tvjl.2020.105424

45. Ag-Conjugated graphene quantum dots with blue light-enhanced singlet oxygen generation for ternary-mode highly-efficient antimicrobial therapy

Author:
Yunjian Yu; Lin Mei; Yanmei Shi; Xinge Zhang; Kesong Cheng; Fengyi Cao; Liuxue Zhang; Jia Xu; Xiumin Li; Zhenlong Xu
Source:
Journal of materials chemistry B 2020 v.8 no.7 pp. 1371-1382
ISSN:
2050-7518
Subject:
Gram-positive bacteria; antibiotic resistance; antibiotics; energy; fever; graphene; irradiation; medicine; nanocomposites; nanosilver; photochemical reactions; photochemotherapy; photothermotherapy; quantum dots; rats; singlet oxygen
Abstract:
... The increasing prevalence of antibiotic resistance highlights the need for new antibacterial drugs and, in particular, the development of alternative approaches such as photodynamic therapy (PDT) and photothermal therapy (PTT) to manage this growing issue. In the present study, a broad-spectrum antibacterial system was produced in which Ag nanoparticle-conjugated graphene quantum dots (GQD–AgNP) w ...
DOI:
10.1039/c9tb02300c

46. Ag-doped magnetic metal organic framework as a novel nanostructured material for highly efficient antibacterial activity

Author:
Ziba Rahmati; Jafar Abdi; Manouchehr Vossoughi; Iran Alemzadeh
Source:
Environmental research 2020 v.188 pp. 109555
ISSN:
0013-9351
Subject:
4',6-diamidino-2-phenylindole; Escherichia coli; Staphylococcus aureus; ambient temperature; antibacterial properties; antibiotics; coordination polymers; fluorescence; fluorescence microscopy; growth retardation; liquids; magnetism; minimum inhibitory concentration; pollution; porous media; research; silver; viability; zinc
Abstract:
... In the last decades, numerous attempts have been made to prevent microbial pollution spreading, using antibacterial agents. Zeolitic imidazolate framework-8 (ZIF-8) belongs to a subgroup of metal organic frameworks (MOFs) merits of attention due to the zinc ion clusters and its effective antibacterial activity. In this work, Ag-doped magnetic microporous γ-Fe₂O₃@SiO₂@ZIF-8-Ag (FSZ-Ag) was successf ...
DOI:
10.1016/j.envres.2020.109555

47. Agar/κ-carrageenan/montmorillonite nanocomposite hydrogels for wound dressing applications

Author:
Tülin Gürkan Polat; Osman Duman; Sibel Tunç
Source:
International journal of biological macromolecules 2020 v.164 pp. 4591-4602
ISSN:
0141-8130
Subject:
Escherichia coli; analgesics; antibacterial properties; antibiotics; chloramphenicol; glucose; hydrogels; lidocaine; nanocomposites; sodium chloride; toxicity testing; urine
Abstract:
... In this study, agar/κ-carrageenan/montmorillonite (MMT) hydrogels were prepared to examine their usability as wound dressing materials and to see the effect of MMT amount on some properties of agar/κ-carrageenan hydrogel materials. Hydrogels were characterized by SEM-EDX, TEM and DSC analyses. By increasing the MMT content within hydrogel matrix from 0% to 5%, the decomposition temperature of the ...
DOI:
10.1016/j.ijbiomac.2020.09.048

48. Aggregated Amphiphilic Antimicrobial Peptides Embedded in Bacterial Membranes

Author:
Haoning Gong; Mingrui Liao; Xuzhi Hu; Ke Fa; Sorasak Phanphak; Daniela Ciumac; Peter Hollowell; Kangcheng Shen; Luke A. Clifton; Mario Campana; John R. P. Webster; Giovanna Fragneto; Thomas A. Waigh; Andrew J. McBain; Jian Ren Lu
Source:
ACS applied materials & interfaces 2020 v.12 no.40 pp. 44420-44432
ISSN:
1944-8252
Subject:
antibiotic resistance; antimicrobial peptides; cytotoxicity; hemolysis; hydrophobicity; microscopy; molecular dynamics; neutrons; zeta potential
Abstract:
... Molecular dynamics (MD) simulations, stochastic optical reconstruction microscopy (STORM), and neutron reflection (NR) were combined to explore how antimicrobial peptides (AMPs) can be designed to promote the formation of nanoaggregates in bacterial membranes and impose effective bactericidal actions. Changes in the hydrophobicity of the designed AMPs were found to have a strong influence on their ...
DOI:
10.1021/acsami.0c09931

49. Agricultural activities affect the pattern of the resistome within the phyllosphere microbiome in peri-urban environments

Author:
Qian Xiang; Dong Zhu; Madeline Giles; Roy Neilson; Xiao-Ru Yang; Min Qiao; Qing-Lin Chen
Source:
Journal of hazardous materials 2020 v.382 pp. 121068
ISSN:
0304-3894
Subject:
agricultural land; antibiotic resistance; antibiotic resistance genes; antibiotics; bacterial communities; forest damage; forests; humans; land use; microbiome; phyllosphere; phytobiome; quantitative polymerase chain reaction; soil; watersheds
Abstract:
... The plant microbiome represents a crucial pathway for human exposure to environmental antibiotic resistance. However, little information is available regarding the plant associated resistome in human-related environments at a larger scale. Here, by high-throughput quantitative-PCR chip-based array and amplicon sequencing, we characterized antibiotic resistance genes (ARGs) and bacterial communitie ...
DOI:
10.1016/j.jhazmat.2019.121068

50. L- Alanine specifically potentiates fluoroquinolone efficacy against Mycobacterium persisters via increased intracellular reactive oxygen species

Author:
Junfeng Zhen; Shuangquan Yan; Yuzhu Li; Cao Ruan; Yue Li; Xue Li; Xiaokang Zhao; Xi Lv; Yan Ge; Ulrich Aymard Ekomi Moure; Jianping Xie
Source:
Applied microbiology and biotechnology 2020 v.104 no.5 pp. 2137-2147
ISSN:
0175-7598
Subject:
Mycobacterium smegmatis; Mycobacterium tuberculosis; alanine; alanine dehydrogenase; antibiotics; carboxylic acids; drug resistance; fluoroquinolones; metabolism; mutants; reactive oxygen species; therapeutics; tricarboxylic acid cycle; tuberculosis
Abstract:
... Tuberculosis caused by Mycobacterium tuberculosis remains a major global health concern; M. tuberculosis drug resistance and persistence further fueled the situation. Nutrient supportive therapy was intensively pursued to complement the conventional treatment, as well as their synergy with current antibiotics. To explore whether L-alanine can synergize with fluoroquinolones against M. tuberculosis ...
DOI:
10.1007/s00253-020-10358-9

51. Algal metabolites: An inevitable substitute for antibiotics

Author:
Sukanya Bhowmick; Aninda Mazumdar; Amitava Moulick; Vojtech Adam
Source:
Biotechnology advances 2020 v.43 pp. 107571
ISSN:
0734-9750
Subject:
algae; antibacterial properties; antibiotic resistance; antibiotics; cost effectiveness; ecosystems; freshwater; pharmaceutical industry; secondary metabolites; virulent strains
Abstract:
... Antibiotic resistance is rising at a pace that is difficult to cope with; circumvention of this issue requires fast and efficient alternatives to conventional antibiotics. Algae inhabit a wide span of ecosystems, which contributes to their ability to synthesize diverse classes of highly active biogenic metabolites. Here, for the first time, we reviewed all possible algal metabolites with broad spe ...
DOI:
10.1016/j.biotechadv.2020.107571

52. Aliarcobacter butzleri from Water Poultry: Insights into Antimicrobial Resistance, Virulence and Heavy Metal Resistance

Author:
Eva Müller; Mostafa Y. Abdel-Glil; Helmut Hotzel; Ingrid Hänel; Herbert Tomaso
Source:
Genes 2020 v.11 no.9 pp. -
ISSN:
2073-4425
Subject:
Cairina moschata; antibiotic resistance; antibiotics; databases; enteritis; farms; food contamination; human diseases; metal tolerance; new combination; new genus; pathogens; poultry; rearing; resistance genes; virulence; Germany
Abstract:
... Aliarcobacter butzleri is the most prevalent Aliarcobacter species and has been isolated from a wide variety of sources. This species is an emerging foodborne and zoonotic pathogen because the bacteria can be transmitted by contaminated food or water and can cause acute enteritis in humans. Currently, there is no database to identify antimicrobial/heavy metal resistance and virulence-associated ge ...
DOI:
10.3390/genes11091104

53. Alleviated Antibiotic-Resistant Genes in the Rhizosphere of Agricultural Soils with Low Antibiotic Concentration

Author:
Mengke Song; Ke Peng; Longfei Jiang; Dayi Zhang; Dandan Song; Guoen Chen; Huijuan Xu; Yongtao Li; Chunling Luo
Source:
Journal of agricultural and food chemistry 2020 v.68 no.8 pp. 2457-2466
ISSN:
1520-5118
Subject:
agricultural soils; antibiotic resistance genes; antibiotics; crops; manure amendments; rhizosphere
Abstract:
... The influence of the rhizosphere on the abundance and diversity of antibiotic resistance genes (ARGs) has been recognized but there is a lack of consensus because of broad ranges of plant species and antibiotic concentrations across different habitats and the elusive underlying mechanisms. Here, we profiled antibiotic concentrations and resistomes in the rhizosphere and bulk soils by cultivating 1 ...
DOI:
10.1021/acs.jafc.9b06634

54. Allicin pharmacology: Common molecular mechanisms against neuroinflammation and cardiovascular diseases

Author:
Feres José Mocayar Marón; Alejandra Beatriz Camargo; Walter Manucha
Source:
Life sciences 2020 v.249 pp. 117513
ISSN:
0024-3205
Subject:
Allium sativum; allicin; antibiotics; antineoplastic activity; antioxidants; antiparasitic agents; bioactive compounds; cardiovascular diseases; garlic; inflammation; mitochondria; nephroprotective effect; odors; oxidative stress; spices; sulfenic acids; therapeutics; thioesters; traditional medicine
Abstract:
... According to investigations in phytomedicine and ethnopharmacology, the therapeutic properties of garlic (Allium sativum) have been described by ancestral cultures. Notwithstanding, it is of particular concern to elucidate the molecular mechanisms underlying this millenary empirical knowledge. Allicin (S-allyl prop-2-ene-1-sulfinothioate), a thioester of sulfenic acid, is one of the main bioactive ...
DOI:
10.1016/j.lfs.2020.117513

55. Allicin reduces inflammation by regulating ROS/NLRP3 and autophagy in the context of A. fumigatus infection in mice

Author:
Jingjing Dai; Ying Chen; Feng Jiang
Source:
Gene 2020 v.762 pp. 145042
ISSN:
0378-1119
Subject:
Aspergillus; Western blotting; allicin; animal experimentation; antibiotics; antimicrobial properties; autophagy; body weight; dose response; environment; flow cytometry; fluorescence microscopes; fluorescence microscopy; fluorescent dyes; fungal spores; fungi; genes; infection; infectious diseases; inflammation; intravenous injection; lungs; mice; pH; spore germination; survival rate; weight
Abstract:
... Inhibitory effect of allicin with broad-spectrum antimicrobial activity on A. fumigatus and the regulation mechanism of inflammation and autophagy in vitro and in vivo.The corresponding concentration of allicin was prepared according to the needs of the experiment. In vitro, 2 ml 5 × 10⁴ of fungal spores suspension was added to the 6-well plate per hole, and different final concentrations of allic ...
DOI:
10.1016/j.gene.2020.145042

56. Alteration of Bacterial Communities in Anterior Nares and Skin Sites of Patients Undergoing Arthroplasty Surgery: Analysis by 16S rRNA and Staphylococcal-Specific tuf Gene Sequencing

Author:
Søren Iversen; Thor Bech Johannesen; Anna Cäcilia Ingham; Sofie Marie Edslev; Staffan Tevell; Emeli Månsson; Åsa Nilsdotter-Augustinsson; Bo Söderquist; Marc Stegger; Paal Skytt Andersen
Source:
Microorganisms 2020 v.8 no.12 pp. -
ISSN:
2076-2607
Subject:
Corynebacterium; Staphylococcus aureus; Staphylococcus epidermidis; Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus pasteuri; antibiotics; bacterial communities; biomass; chlorhexidine; disease control; gluconates; hips; microorganisms; nose; patients; sampling; sequence analysis; soaps; species diversity; surgery
Abstract:
... The aim was to study alterations of bacterial communities in patients undergoing hip or knee arthroplasty to assess the impact of chlorhexidine gluconate soap decolonisation and systemic antibiotic prophylaxis. A Swedish multicentre, prospective collection of samples obtained from elective arthroplasty patients (n = 83) by swabbing anterior nares, skin sites in the groin and the site of planned su ...
DOI:
10.3390/microorganisms8121977

57. Alteration of the gut microbiota by vinegar is associated with amelioration of hyperoxaluria-induced kidney injury

Author:
Wei Zhu; Yang Liu; Xiaolu Duan; Chenglin Xiao; Yu Lan; Lianmin Luo; Chengjie Wu; Zhou Yang; Xin Mai; Suilin Lu; Wen Zhong; Shujue Li; Zihao He; Xin Zhang; Yongda Liu; Guohua Zeng
Source:
Food & function 2020 v.11 no.3 pp. 2639-2653
ISSN:
2042-650X
Subject:
Prevotella; animal models; antibiotics; biosynthesis; biotin; blood serum; creatinine; ethylene glycol; fibrosis; genes; glycerol; inflammation; intestinal microorganisms; kidney diseases; kidneys; lipid metabolism; liquid chromatography; mass spectrometry; metabolites; metabolomics; oral administration; phosphates; phosphatidylcholines; protective effect; rats; renal function; ribosomal RNA; thiamin; urine; vinegars
Abstract:
... Hyperoxaluria is well known to cause renal injury and end-stage kidney disease. Previous studies suggested that the renal function of rats with hyperoxaluria was improved after dietary vinegar intake. However, its underlying mechanisms remain largely unknown. The aim of the present study was to examine changes of gut microbiota and blood and urinary metabolites that associate with changes in kidne ...
DOI:
10.1039/c9fo02172h

58. Alterations in the Gut Microbiome at 6 Months of Age in Obese Latino Infants

Author:
Annette Ville; Emma Levine; Degui Zhi; Barbara Lararia; Janet M. Wojcicki
Source:
Journal of the American College of Nutrition 2020 v.39 no.1 pp. 47-53
ISSN:
1541-1087
Subject:
Latinos; anthropometric measurements; antibiotics; breast feeding; dietary exposure; infants; intestinal microorganisms; obesity; species diversity
Abstract:
... Objective: To investigate gut microbial composition in Latino infants in relation to breastfeeding, obesity, and antibiotic exposure. Method: We analyzed the gut microbiome in 6-month-old Latino infants from an ongoing urban mother–child cohort. Alpha and beta diversity were assessed in relation to infants’ early dietary exposure and anthropometrics including obesity. Results: Infants exclusively ...
DOI:
10.1080/07315724.2019.1606744
PubMed:
31498715
PubMed Central:
PMC6949412

59. Alterins Produced by Oyster-Associated Pseudoalteromonas Are Antibacterial Cyclolipopeptides with LPS-Binding Activity

Author:
Florie Desriac; Abderrafek El Harras; Matthieu Simon; Arnaud Bondon; Benjamin Brillet; Patrick Le Chevalier; Martine Pugnière; Patrice Got; Delphine Destoumieux-Garzón; Yannick Fleury
Source:
Marine drugs 2020 v.18 no.12 pp. -
ISSN:
1660-3397
Subject:
Gram-negative bacteria; Pseudoalteromonas; animal pathogens; antibacterial properties; antibiotics; carbon; hemolymph; homeostasis; hosts; hydrophobicity; immune system; immunity; length; lipopolysaccharides; mechanism of action; nutrition; oysters; permeability; strains; tail
Abstract:
... Discovery after discovery, host-associated microbiota reveal a growing list of positive effects on host homeostasis by contributing to host nutrition, improving hosts’ immune systems and protecting hosts against pathogens. In that context, a collection of oyster associated bacteria producing antibacterial compounds have been established to evaluate their role in non-host-derived immunity. Here, we ...
DOI:
10.3390/md18120630

60. Ameliorative Effects of Antibiotic-, Probiotic- and Phytobiotic-Supplemented Diets on the Performance, Intestinal Health, Carcass Traits, and Meat Quality of Clostridium perfringens-Infected Broilers

Author:
Elsayed O.S. Hussein; Shamseldein H. Ahmed; Alaeldein M. Abudabos; Gamaleldin M. Suliman; Mohamed E. Abd El-Hack; Ayman A. Swelum; Abdullah N. Alowaimer
Source:
Animals 2020 v.10 no.4 pp. -
ISSN:
2076-2615
Subject:
Bacillus subtilis; Clostridium perfringens; antibiotics; chewiness; feed conversion; hardness; intestines; meat quality; mixed infection; models; necrotic enteritis; phytonutrients; poultry industry; prebiotics; probiotics; sanguinarine; spleen; survival rate; temperature; texture
Abstract:
... The poultry industry needs efficient antibiotic alternatives to prevent necrotic enteritis (NE) infections. Here, we evaluate the effects of probiotic and/or prebiotic dietary supplementation on performance, meat quality and carcass traits, using only an NE coinfection model, in broiler chickens. Three hundred and twenty-four healthy Ross 308 broiler chicks are allocated into six groups. Taking a ...
DOI:
10.3390/ani10040669

61. The Amino Acid Changes T55A, A273P and R277C in the Beta-Lactamase CTX-M-14 Render E. coli Resistant to the Antibiotic Nitrofurantoin, a First-Line Treatment of Urinary Tract Infections

Author:
Yasir Edowik; Thomas Caspari; Hugh Merfyn Williams
Source:
Microorganisms 2020 v.8 no.12 pp. -
ISSN:
2076-2607
Subject:
active sites; adults; amino acids; antibiotics; beta-lactamase; cell free system; detection; hospitals; incidence; microorganisms; minimum inhibitory concentration; missense mutation; multiple drug resistance; nitrofurantoin; patients; polymerase chain reaction; rendering; resistance genes; urinary tract diseases; uropathogenic Escherichia coli; women; Wales
Abstract:
... The antibiotic nitrofurantoin is a furan flanked by a nitro group and a hydantoin ring. It is used to treat lower urinary tract infections (UTIs) that have a lifetime incidence of 50-60% in adult women. UTIs are typically caused by uropathogenic Escherichia coli (UPEC), which are increasingly expressing extended-spectrum beta-lactamases (ESBL), rendering them multi-drug resistant. Nitrofurantoin i ...
DOI:
10.3390/microorganisms8121983

62. Amorphous cobalt boride nanosheets anchored surface-functionalized carbon nanofiber: An bifunctional and efficient catalyst for electrochemical sensing and oxygen evolution reaction

Author:
Ramaraj Sukanya; Shen-Ming Chen
Source:
Journal of colloid and interface science 2020 v.580 pp. 318-331
ISSN:
0021-9797
Subject:
Raman spectroscopy; X-ray diffraction; X-ray photoelectron spectroscopy; active sites; antibiotics; carbon; carbon nanofibers; catalysts; catalytic activity; cobalt; detection limit; dielectric spectroscopy; electrical conductivity; electrochemistry; electrodes; nanosheets; nitrofurantoin; oxygen production; scanning electron microscopy; sensors (equipment); surface area; synergism; transmission electron microscopy
Abstract:
... Development of new metal boride with carbon composite is an emerging class of catalyst and it brings enormous curiosity in the material community because of their potential intriguing properties. Here, we describe a new type of amorphous cobalt boride (A-CoB) nanosheet anchored on the surface of functionalized carbon nanofiber (A-CoB/ƒ-CNF) by a simple method. The emerged A-CoB/ƒ-CNF composite was ...
DOI:
10.1016/j.jcis.2020.07.037

63. Anaerobic Transformation and Detoxification of Sulfamethoxazole by Sulfate-Reducing Enrichments and Desulfovibrio vulgaris

Author:
Wei-Ying Ouyang; Jan Birkigt; Hans Hermann Richnow; Lorenz Adrian
Source:
Environmental science & technology 2020 v.55 no.1 pp. 271-282
ISSN:
1520-5851
Subject:
Desulfovibrio vulgaris; antibacterial properties; antibiotics; constructed wetlands; isomerization; methanogens; moieties; oxygen; sediments; sludge; sulfamethoxazole; wastewater; wastewater treatment
Abstract:
... Sulfamethoxazole (SMX) is a veterinary antibiotic that is not efficiently removed from wastewater by routine treatment and therefore can be detected widely in the environment. Here, we investigated whether microbial anaerobic transformation can contribute to the removal of SMX in constructed systems. We enriched SMX-transforming mixed cultures from sediment of a constructed wetland and from digest ...
DOI:
10.1021/acs.est.0c03407

64. Analysis of Complete Genome Sequence of Acinetobacterbaumannii Strain ATCC 19606 Reveals Novel Mobile Genetic Elements and Novel Prophage

Author:
Mohammad Hamidian; Lucia Blasco; Lauren N. Tillman; Joyce To; María Tomas; Garry S. A. Myers
Source:
Microorganisms 2020 v.8 no.12 pp. -
ISSN:
2076-2607
Subject:
Acinetobacter baumannii; antibiotic resistance; antibiotics; cadmium; genes; mercury; microorganisms; models; pathogenesis; plasmids; strains; transposons
Abstract:
... Acinetobacter baumannii isolate ATCC 19606 was recovered in the US prior to 1948. It has been used as a reference and model organism in many studies involving antibiotic resistance and pathogenesis of A. baumannii, while, until recently, a complete genome of this strain was not available. Here, we present an analysis of the complete 3.91-Mbp genome sequence, generated via a combination of short-re ...
DOI:
10.3390/microorganisms8121851

65. Analysis of Eurasian Stone curlew (Burhinus oedicnemus) microbial flora reveals the presence of multi-drug resistant pathogens in agro-pastoral areas of Sicily (Italy)

Author:
Maria Foti; Rosario Grasso; Vittorio Fisichella; Antonietta Mascetti; Manuel Andrea Zafarana; Marco Colnaghi; Maria Grasso; Maria Teresa Spena
Source:
Heliyon 2020 v.6 no.10 pp. e05401
ISSN:
2405-8440
Subject:
Burhinus; agar; antibiotic resistance; antibiotics; beak; disk diffusion antimicrobial test; eyes; feces; humans; microbiome; multiple drug resistance; risk; wild birds; wildlife; Italy; Sicily
Abstract:
... Spread of multi-drug resistant (MDR) bacteria in natural environments pose a risk to human and animal health. Wild birds are considered to be reservoirs of human pathogens and vectors of antimicrobial resistance distribution in the environment. The aim of this study is to assess the occurrence of antibiotic resistant bacteria in isolates from bird specimens living in three agro-pastoral areas of t ...
DOI:
10.1016/j.heliyon.2020.e05401

66. Analysis of a bac operon-silenced strain suggests pleiotropic effects of bacilysin in Bacillus subtilis

Author:
Ozan Ertekin; Meltem Kutnu; Aslı Aras Taşkin; Mustafa Demir; Ayten Yazgan Karataş; Gülay Özcengiz
Source:
journal of microbiology 2020 v.58 no.4 pp. 297-313
ISSN:
1225-8873
Subject:
Bacillus subtilis; alanine; antibiotics; bioassays; coat proteins; gene expression regulation; germination; messenger RNA; morphogenesis; open reading frames; operon; peptides; phenotype; pigmentation; pleiotropy; protein synthesis; proteome; proteomics; quorum sensing; regulon; spores; sporulation; stress response; tandem mass spectrometry; transcription (genetics)
Abstract:
... Bacilysin, as the simplest peptide antibiotic made up of only L-alanine and L-anticapsin, is produced and excreted by Bacillus subtilis under the control of quorum sensing. We analyzed bacilysin-nonproducing strain OGU1 which was obtained by bacA-targeted pMutin T3 insertion into the parental strain genome resulting in a genomic organization (bacA′::lacZ::erm::bacABCDEF) to form an IPTG-inducible ...
DOI:
10.1007/s12275-020-9064-0

67. Analysis of bacterial microbiome associated with nylon and copper nets in an aquaculture context

Author:
Paula Canada; Ana Pereira; Natacha Nogueira; Lydia Png-Gonzalez; Carlos Andrade; Raquel Xavier
Source:
Aquaculture 2020 v.516 pp. 734540
ISSN:
0044-8486
Subject:
Tenacibaculum; animal welfare; antibiotics; antimicrobial properties; bacteria; bacterial communities; biofilm; biofouling; copper; durability; fish; fish culture; fish farms; high-throughput nucleotide sequencing; microbiome; monitoring; netting; nylon; pathogens; profitability; ribosomal RNA; species diversity; tanks; virulence
Abstract:
... Bacterial pathogens represent a huge challenge for aquaculture profitability and fish welfare, particularly since they can naturally occur in the water column and fish microbiomes, appear associated with biofouling or establish biofilms on tanks, gear and nets. Recently, several studies have shown how biofilms can become important pathogen reservoirs within fish farms, particularly since they conf ...
DOI:
10.1016/j.aquaculture.2019.734540

68. Analysis of fecal samples from Amami rabbits (Pentalagus furnessi) indicates low levels of antimicrobial resistance in Escherichia coli

Author:
Nonoka Matsunaga; Mariko Suzuki; Masako Andoh; Moe Ijiri; Kemi Ishikawa; Takeshi Obi; Takehisa Chuma; Yoshikazu Fujimoto
Source:
European journal of wildlife research 2020 v.66 no.5 pp. 84
ISSN:
1612-4642
Subject:
Escherichia coli; antibiotic resistance; antibiotics; bacteria; feces; indigenous species; livestock; minimum inhibitory concentration; monitoring; population dynamics; rabbits; rare species; wildlife; wildlife habitats
Abstract:
... In recent years, antimicrobial-resistant bacteria have been isolated from different wildlife species that have not been exposed to antibiotics. Antimicrobial resistance profile analysis of wildlife-derived Escherichia coli is one of the ways to obtain information about changes in wildlife habitats. The Amami rabbit (Pentalagus furnessi) is one of the Japanese endemic wildlife species that requires ...
DOI:
10.1007/s10344-020-01424-8

69. Analysis, occurrence and removal of pharmaceuticals in African water resources: A current status

Author:
Lawrence Mzukisi Madikizela; Somandla Ncube; Luke Chimuka
Source:
Journal of environmental management 2020 v.253 pp. 109741
ISSN:
0301-4797
Subject:
antibiotics; antiretroviral agents; environmental monitoring; nonsteroidal anti-inflammatory agents; organic compounds; pain; remediation; researchers; scientists; steroid hormones; water pollution; water resources; South Africa
Abstract:
... Pharmaceuticals are organic compounds used in medicines for alleviation of pain. Since 2017, there has been a steady increase on the availability of information on contamination of water resources caused by pharmaceuticals in some African countries. Thus far, most environmental monitoring studies of pharmaceuticals are conducted in South Africa while there is still no available data in majority of ...
DOI:
10.1016/j.jenvman.2019.109741

70. Antagonistic activity of combined bacteria strains against southern blight pathogen of Dendrobium officinale

Author:
Yong-Chang Shen; Nartey Linda Korkor; Rong Xiao; Qian Pu; Miao Hu; Shuai-Shuai Zhang; De-Dong Kong; Guohong Zeng; Xiu-Fang Hu
Source:
Biological control 2020 v.151 pp. 104291
ISSN:
1049-9644
Subject:
Athelia rolfsii; Bacillus (bacteria); Dendrobium officinale; Pseudomonas; Sclerotium (genus); Sphingomonas; antibiotics; antifungal properties; bacteria; biological control; blight; genes; iturin; medicinal plants; niches; pathogens; polymerase chain reaction; siderophores; surfactin
Abstract:
... The aim of the study was to determine the in vitro and in vivo antagonistic potential of combined bacteria strains against Sclerotium rolfsii inducing southern blight on Dendrobium officinale.Antagonistic or growth-promoting bacteria such as Bacillus, Pseudomonas and Sphingomonas strains isolated from D. officinale and other medicinal herbs were tested for antagonistic activity against S. rolfsii, ...
DOI:
10.1016/j.biocontrol.2020.104291

71. Antecedent Dietary Glutamine Supplementation Benefits Modulation of Liver Pyroptosis in Mice with Polymicrobial Sepsis

Author:
Man-Hui Pai; Jin-Ming Wu; Po-Jen Yang; Po-Chu Lee; Chun-Chieh Huang; Sung-Ling Yeh; Ming-Tsan Lin
Source:
Nutrients 2020 v.12 no.4 pp. -
ISSN:
2072-6643
Subject:
antibiotics; bacterial infections; casein; caspase-11; cytokines; endotoxins; gene expression; glutamine; immunomodulators; inflammation; lead; liver; mice; nutrients; pathogens; pretreatment; protein content; pyroptosis
Abstract:
... The liver is the main organ responsible for bacterial and endotoxin clearance. Pyroptosis is a form of proinflammatory programmed cell death activated by caspase-1/11 and gasdermin D (GadD). Pyroptosis protects the host against bacterial infection; however, overactive pyroptosis can lead to organ injury. Glutamine (GLN) is a specific amino acid with anti-inflammatory and immunomodulatory propertie ...
DOI:
10.3390/nu12041086

72. Antemortem diagnosis and surgical management of a rectum intussusception and cloacal wall prolapse in a hybrid falcon (F. cherrug x F. peregrinus) associated with bacterial enteritis

Author:
Ciro Cococcetta; Diana Binanti; Giorgia Matteucci; Tommaso Collarile; Paolo Selleri
Source:
Journal of exotic pet medicine 2020 v.33 pp. 10-13
ISSN:
1557-5063
Subject:
Aquila; Buteo; Escherichia coli; Falco cherrug; Falco peregrinus; Parabuteo; anorexia; antibiotics; bacterial enteritis; birds of prey; breeding; cloaca; endoscopy; enteropathogens; falcons; females; histopathology; hybrids; intestinal obstruction; parasitoses; patients; radiography; rectum
Abstract:
... Background: Rectal intussusception associated with cloacal wall prolapse is a serious and potentially life-threatening condition. In raptors, cloacal prolapse associated with enteritis has only been described in the genera Buteo, Parabuteo, and Aquila. Four cases of intussusception and cloacal prolapse were reported in kestrel with severe parasitosis. The aim of this report is to describe a case i ...
DOI:
10.1053/j.jepm.2020.01.004

73. Anti-Mycobacterial Antibiotic Therapy Induces Remission in Active Paediatric Crohn’s Disease

Author:
Gaurav Agrawal; Harrison Hamblin; Annabel Clancy; Thomas Borody
Source:
Microorganisms 2020 v.8 no.8 pp. -
ISSN:
2076-2607
Subject:
Crohn disease; Mycobacterium avium; adverse effects; antibiotics; blood serum; hemoglobin; immunosuppression; immunotherapy; paratuberculosis; patients; remission
Abstract:
... Crohn’s disease is increasing in incidence and prevalence in younger people and is of a particularly aggressive nature. One emerging treatment targets Mycobacterium avium paratuberculosis (MAP), an organism implicated in the causation of Crohn’s disease. This study reviewed a cohort of paediatric patients with active Crohn’s disease treated with Anti-Mycobacterial Antibiotic Therapy (AMAT). Sixtee ...
DOI:
10.3390/microorganisms8081112

74. Anti-bacterial and skin-cancer activity of AuNP, rGO and AuNP-rGO composite using Hemigraphis alternata (Burm.F.) T. Anderson

Author:
Santhiya Sasidharan; Lalitha Pottail
Source:
Biocatalysis and agricultural biotechnology 2020 v.25 pp. 101596
ISSN:
1878-8181
Subject:
Fourier transform infrared spectroscopy; Gram-negative bacteria; Hemigraphis alternata; Raman spectroscopy; X-ray diffraction; acridine orange; ambient temperature; antibiotics; apoptosis; cell lines; cell viability; chemical constituents of plants; color; differential thermal analysis; ethidium; graphene oxide; homogenization; infectious diseases; leaves; medicinal plants; nanocomposites; nanogold; nanoparticles; neoplasm cells; propidium; reducing agents; scanning electron microscopy; screening; skin neoplasms; staining; therapeutics; thermogravimetry; ultraviolet-visible spectroscopy
Abstract:
... Hemigraphis alternata (HA) known as Murikuti, is a traditionally used medicinal plant. Phytochemical screening of leaves shows the presence of bioactive reducing agents. Gold nanoparticles were prepared using aqueous extract of HA leaves at various conventional methods. Concentration variation of gold nanoparticles was studied and optimized under room temperature conditions. Gold nanoparticles (vi ...
DOI:
10.1016/j.bcab.2020.101596

75. Anti-microbial and anti-biofilm activities of combined chelerythrine-sanguinarine and mode of action against Candida albicans and Cryptococcus neoformans in vitro

Author:
Weidong Qian; Min Yang; Xinchen Li; Zhaohuan Sun; Yongdong Li; Xuejun Wang; Ting Wang
Source:
Colloids and surfaces 2020 v.191 pp. 111003
ISSN:
0927-7765
Subject:
Candida albicans; Cryptococcus neoformans; adhesion; antibiotics; antifungal agents; antifungal properties; biofilm; cell membranes; drug resistance; fungi; mechanism of action; minimum inhibitory concentration; pathogens; sanguinarine
Abstract:
... The increasing prevalence of fungal infections coupled with emerging drug resistance has stimulated an urgent need to explore new and effective antifungal agents. Sanguinarine and chelerythrine constitute alkaloids that have exhibited antifungal activities. However, the effects of a 1:1 mixture of these agents against Candida albicans and Cryptococcus neoformans have remained largely unexplored. T ...
DOI:
10.1016/j.colsurfb.2020.111003

76. Antibacterial Activities of Novel Dithiocarbamate-Containing 4H-Chromen-4-one Derivatives

Author:
Shichun Jiang; Shijun Su; Mei Chen; Feng Peng; Qing Zhou; Tingting Liu; Liwei Liu; Wei Xue
Source:
Journal of agricultural and food chemistry 2020 v.68 no.20 pp. 5641-5647
ISSN:
1520-5118
Subject:
Ralstonia solanacearum; Xanthomonas axonopodis pv. citri; Xanthomonas oryzae pv. oryzae; antibacterial properties; antibiotics; bioassays; cell membranes; copper; deformation; enzyme activity; enzymes; mechanism of action; median effective concentration; plant pathogens; scanning electron microscopy
Abstract:
... To aid the development of novel antibacterial agents that possess a innovative mechanism of action, we built a series of novel dithiocarbamate-containing 4H-chromen-4-one derivatives. We evaluated the activities of the derivatives against three plant pathogens Xanthomonas oryzae pv oryzae (X. oryzae pv o.), Ralstonia solanacearum (R. solanacearum), and Xanthomonas axonopodis pv citri (X. axonopodi ...
DOI:
10.1021/acs.jafc.0c01652

77. Antibacterial Activity and Mode of Action of Lactoquinomycin A from Streptomyces bacillaris

Author:
Beomkoo Chung; Oh-Seok Kwon; Jongheon Shin; Ki-Bong Oh
Source:
Marine drugs 2020 v.19 no.1 pp. -
ISSN:
1660-3397
Subject:
DNA damage; DNA repair; Gram-negative bacteria; Gram-positive bacteria; Salmonella enterica; Streptomyces bacillaris; antibacterial properties; antibiotics; assays; gels; incidence; mechanism of action; methicillin-resistant Staphylococcus aureus; minimum inhibitory concentration; plasmids; protein synthesis; spectroscopy
Abstract:
... This study aims to isolate and identify the structure of antibacterial compounds having potent activity on methicillin-resistant Staphylococcus aureus (MRSA) from marine actinomycetes, and also to identify their mode of action. Lactoquinomycin A (LQM-A) (compound 1) and its derivatives (2–4) were isolated from marine-derived Streptomyces bacillaris strain MBTC38, and their structures were determin ...
DOI:
10.3390/md19010007

78. The Antibacterial Activity of Actinomycetes Against the Growth of Streptococcus mutans and Lactobacillus acidophilus

Author:
Kania Tri Putri Deby; Amirda Fadel; Muzadi Hilman; Nindia Carabelly Amy; Erlita Isyana; Rahmiati
Source:
BIO web of conferences 2020 v.20 no. pp. 03006
ISSN:
2117-4458
Subject:
Actinobacteria; Lactobacillus acidophilus; Streptococcus mutans; antibacterial properties; antibiotics; chlorhexidine; gluconates; secondary metabolites; soil; soil bacteria
Abstract:
... Antibacterial compounds are generally produced from many herbal ingredients, but antibacterials may be produced from soil microbes, one of which is Actinomycetes. Actinomycetes are a soil bacterium capable of producing secondary metabolites in the form of antibacterial compounds. The antibacterial compound has the potential as an alternative antibacterial agent against oral microbes. One of the or ...
DOI:
10.1051/bioconf/20202003006

79. Antibacterial activities and mechanisms of action of a defensin from manila clam Ruditapes philippinarum

Author:
Chengjie Lv; Yijing Han; Dinglong Yang; Jianmin Zhao; Chunlin Wang; Changkao Mu
Source:
Fish & shellfish immunology 2020 v.103 pp. 266-276
ISSN:
1050-4648
Subject:
Ruditapes philippinarum; Vibrio anguillarum; antibacterial properties; antibiotics; antimicrobial peptides; biofilm; cell death; chemotaxis; clams; electrochemistry; gills; hemocytes; immunohistochemistry; mechanism of action; membrane permeability; messenger RNA; microorganisms; mortality; phagocytosis; phylogeny; reverse transcriptase polymerase chain reaction; scanning electron microscopy; tissues
Abstract:
... Defensins represent an evolutionary ancient family of antimicrobial peptides, which played an undeniably important role in host defense. In the present study, a defensin isoform was identified and characterized from manila clam Ruditapes philippinarum (designed as Rpdef1α). Multiple alignments and phylogenetic analysis suggested that Rpdef1α belonged to the defensin family. Quantitative RT-PCR and ...
DOI:
10.1016/j.fsi.2020.05.025

80. Antibacterial activity of CaO from blood cockle shells (Anadara granosa) calcination against Escherichia coli

Author:
AMANDA FIRZA RUSDARYANTI; ULFAH AMALIA; SLAMET SUHARTO
Source:
Biodiversitas 2020 v.21 no.6 pp. -
ISSN:
2085-4722
Subject:
DNA; Escherichia coli; Tegillarca granosa; analysis of variance; antibacterial properties; antibiotics; blood; calcium carbonate; calcium oxide; minimum inhibitory concentration; pH
Abstract:
... Rusdaryanti AF, Amalia U, Suharto S. 2020. Antibacterial activity of CaO from blood cockle shells (Anadara granosa) calcination against Escherichia coli. Biodiversitas 21: 2826-2830. Calcium carbonate (CaCO3) in blood clamp shells (BCS) was able to be converted into calcium oxide (CaO) through a calcination process. Some research stated that CaO can be used in the food industries b, one of which i ...
DOI:
10.13057/biodiv/d210660

81. Antibacterial activity of Siparuna guianensis essential oil mediated by impairment of membrane permeability and replication of pathogenic bacteria

Author:
Wellington de Souza Moura; Silvania Rosa de Souza; Fabrício S. Campos; Alex Sander Rodrigues Cangussu; Eliane Macedo Sobrinho Santos; Bruno Silva Andrade; Cesar Henrique Borges Gomes; Kelvinson Fernandes Viana; Khalid Haddi; Eugenio Eduardo Oliveira; Vitor L. Nascimento; Raimundo Wagner de Souza Aguiar
Source:
Industrial crops and products 2020 v.146 pp. 112142
ISSN:
0926-6690
Subject:
DNA; Escherichia coli; Pseudomonas aeruginosa; RNA; Siparuna; Staphylococcus aureus; Streptococcus pyogenes; active sites; antibacterial properties; antibiotics; bacteria; bacterial growth; cell walls; computer simulation; cytotoxicity; enzymes; essential oils; gas chromatography; germacrene; growth retardation; human cell lines; ions; membrane permeability; myrcene; nucleotides; potassium; prediction; virulent strains
Abstract:
... The increasing prevalence of resistance to conventional antibiotics in pathogenic bacteria has demanded faster development of novel sources of antibacterial agents. In this context, biological activities shown by natural compounds have received particular attention. One of the alleged backslashes for these alternative bactericidal tools is the current knowledge gap regarding their action mechanism ...
DOI:
10.1016/j.indcrop.2020.112142

82. Antibacterial activity of salvia officinalis L. against periodontopathogens: An in vitro study

Author:
Filipe Santos Ferreira Mendes; Letícia Matanovich Garcia; Thais da Silva Moraes; Luciana Assirati Casemiro; Clauber Barbosa de Alcântara; Sérgio Ricardo Ambrósio; Rodrigo Cássio Sola Veneziani; Mayker Lazaro Dantas Miranda; Carlos Henrique Gomes Martins
Source:
Anaerobe 2020 v.63 pp. 102194
ISSN:
1075-9964
Subject:
Porphyromonas gingivalis; Salvia officinalis; antibacterial properties; antibiotics; bacteria; biofilm; chlorhexidine; gluconates; in vitro studies; methylene chloride; minimum inhibitory concentration; periodontal diseases; therapeutics; viridiflorol
Abstract:
... Being aware of the remarkable antimicrobial potential of S. officinalis L., we aimed to evaluate the antimicrobial activity of the S. officinalis dichloromethane crude extract (SOD), dichloromethane-soluble fractions (SODH and SODD), SODD subfractions (SODD1 and SODD2), and pure substances (manool, salvigenin, and viridiflorol) against periodontopathogens. This bioassay-guided study comprises five ...
DOI:
10.1016/j.anaerobe.2020.102194

83. Antibacterial activity of silver nanoparticles (biosynthesis): A short review on recent advances

Author:
C.G. Anjali Das; V. Ganesh Kumar; T. Stalin Dhas; V. Karthick; K. Govindaraju; J. Mary Joselin; J. Baalamurugan
Source:
Biocatalysis and agricultural biotechnology 2020 v.27 pp. 101593
ISSN:
1878-8181
Subject:
agricultural productivity; algae; antibacterial properties; antibiotics; aquaculture; biosynthesis; chemical industry; food preservation; infectious diseases; nanobiotechnology; nanoparticles; nanosilver; ponds; salts; silver; water treatment
Abstract:
... Silver is a potent antimicrobial agent which is used in the form of nanomaterial or as metal salts for antimicrobial applications. Antimicrobial agents have a major role in water treatment, chemical industries, food preservation, aquaculture ponds, agricultural productivity and biomedical applications. Presently, due to emergence of nanoscience and technology metallic silver nanoparticles (AgNPs) ...
DOI:
10.1016/j.bcab.2020.101593

84. Antibacterial activity of sugar maple autumn‐shed leaf extract: Identification of the active compound

Author:
Maxime Delisle‐Houde; Pascal Dubé; Russell J. Tweddell
Source:
Annals of applied biology 2020 v.177 no.1 pp. 51-60
ISSN:
0003-4746
Subject:
Acer saccharum subsp. saccharum; Pseudomonas cichorii; Xanthomonas campestris pv. vitians; active ingredients; antibacterial properties; antibiotics; glass; leaf extracts; lettuce; silica gel
Abstract:
... Ethanolic crude extract prepared from autumn‐shed leaves of sugar maple (Acer saccharum Marsh.) was recently shown to have antibacterial activity against Pseudomonas cichorii and Xanthomonas campestris pv. vitians, two bacteria causing diseases in lettuce production. In this study, antibacterial activity of sugar maple autumn‐shed leaves (SMASL) extract was further investigated. SMASL ethanolic cr ...
DOI:
10.1111/aab.12598

85. Antibacterial activity of tea saponin from Camellia oleifera shell by novel extraction method

Author:
Ying Zhao; Ruiqi Su; Wenting Zhang; Guang-Long Yao; Jian Chen
Source:
Industrial crops and products 2020 v.153 pp. 112604
ISSN:
0926-6690
Subject:
Camellia oleifera; Escherichia coli; Staphylococcus aureus; adsorption; agricultural income; antibacterial properties; antibiotics; bacteria; bacterial growth; biopreservatives; cell membrane structures; ethanol; foaming; humans; markets; membrane permeability; minimum inhibitory concentration; pH; porous media; purification methods; saponins; tea; toothpaste; toxicity; wastes
Abstract:
... Natural preservatives are substances that are secreted by organisms or present in the body and have bacteriostatic effects, so they are not toxic to humans. Natural preservatives have become a research focus because of their high safety and strong antibacterial effects. Some commodities in the market are added with tea saponins, such as a brand of foaming cleanser, shampoo, and toothpaste rich in ...
DOI:
10.1016/j.indcrop.2020.112604

86. Antibacterial activity of the venom of the Ponerine ant Pachycondyla striata (Formicidae: Ponerinae)

Author:
Pollyanna Pereira Santos; Gracielle Rodrigues Pereira; Edvaldo Barros; Humberto Josué Oliveira Ramos; Leandro Licursi Oliveira; José Eduardo Serrão
Source:
International journal of tropical insect science 2020 v.40 no.2 pp. 393-402
ISSN:
1742-7592
Subject:
Gram-negative bacteria; Gram-positive bacteria; Pachycondyla; allergens; animal pathogens; ant venoms; antibacterial properties; antibiotics; antimicrobial peptides; growth retardation; mass spectrometry; virulent strains
Abstract:
... Animal venom peptides have been reported as potential antimicrobial molecules for the development of novel antibiotics against resistant bacteria. Recent studies indicate that ant venoms is an important source of novel antimicrobial peptides. In the present study, the antimicrobial activity of the venom of the predatory ant Pachycondyla striata Smith, 1858, was evaluated against some pathogenic ba ...
DOI:
10.1007/s42690-019-00090-x

87. Antibacterial activity of viable and heat‐killed probiotic strains against oral pathogens

Author:
Y.‐T. Chen; P.‐S. Hsieh; H.‐H. Ho; S.‐H. Hsieh; Y.‐W. Kuo; S.‐F. Yang; C.‐W. Lin
Source:
Letters in applied microbiology 2020 v.70 no.4 pp. 310-317
ISSN:
0266-8254
Subject:
Actinobacillus actinomycetemcomitans; Bifidobacterium animalis subsp. lactis; Fusobacterium nucleatum; Lactobacillus acidophilus; Lactobacillus paracasei; Lactobacillus rhamnosus; Lactobacillus salivarius subsp. salicinius; Porphyromonas gingivalis; Streptococcus mutans; antibacterial properties; antibiotics; bacteria; drug resistance; dysbiosis; functional foods; hydrogen peroxide; immunity; intestinal microorganisms; intestines; mouth diseases; oral health; pathogens; probiotics
Abstract:
... Probiotics can stabilize gut flora, regulate intestinal immunity and protect the host from enteric diseases; however, their roles in oral health have received little attention compared to their roles in gut health. Nowadays, the prevalence of sugar‐sweetened foods and abuse of antibiotics contribute towards dysbiosis of oral microbiota and drug resistance development in oral pathogens, resulting i ...
DOI:
10.1111/lam.13275

88. Antibacterial and Degradable Thioimidazolium Poly(ionic liquid)

Author:
Christene Anne Smith; Vincenzo Alessandro Cataldo; Thomas Dimke; Ina Stephan; Ryan Guterman
Source:
ACS sustainable chemistry & engineering 2020 v.8 no.22 pp. 8419-8424
ISSN:
2168-0485
Subject:
Pseudomonas aeruginosa; antibacterial properties; antibiotic resistance; antibiotics; bacteria; benzalkonium chloride; biocides; environmental impact; ionic liquids; polymers
Abstract:
... New antibacterial agents are urgently required to fight the emergence of antibiotic-resistant bacteria. We recently synthesized the first thioimidazolium ionene, which has antibacterial properties and can degrade in various media. This dual functionality is crucial in order to limit the environmental impact of these biocides. We have found that our polymer is stronger than benzalkonium chloride (B ...
DOI:
10.1021/acssuschemeng.0c02666

89. Antibacterial and Hemostatic Thiol-Modified Chitosan-Immobilized AgNPs Composite Sponges

Author:
Zhengguo Wu; Wei Zhou; Weijie Deng; Changliang Xu; Yun Cai; Xiaoying Wang
Source:
ACS applied materials & interfaces 2020 v.12 no.18 pp. 20307-20320
ISSN:
1944-8252
Subject:
Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; absorption; antibacterial properties; antibiotics; blood cells; chitosan; hemorrhage; hemostasis; in vivo studies; nanosilver; patients; porosity; synergism; tissue repair; toxicity
Abstract:
... Wound bleeding and infection are two of the major threats to patients’ lives, but developing safe materials with high hemostasis efficiency and antibacterial activity remains a major challenge. Silver nanoparticles (AgNPs) are suitable as antibacterial agents in the hemostatic process, but the application is hampered because of easy accumulation of toxicity. Herein, thiol-modified chitosan (TMC) w ...
DOI:
10.1021/acsami.0c05430

90. Antibacterial and antibiofilm activity of bone marrow-derived human mesenchymal stem cells secretome against Vibrio cholerae

Author:
Mahboube Bahroudi; Bita Bakhshi; Sara Soudi; Shahin Najar-peerayeh
Source:
Microbial pathogenesis 2020 v.139 pp. 103867
ISSN:
0882-4010
Subject:
Vibrio cholerae; adipocytes; antibacterial properties; antibiotic resistance; antibiotics; aquatic environment; biofilm; bone formation; dose response; fearfulness; genetic markers; mesenchymal stromal cells; minimum inhibitory concentration; multiple drug resistance; pathogens; therapeutics
Abstract:
... The ability of V. cholerae to survive and spread in the aquatic environment combined with the scarcity of effective antimicrobial agents, especially those effective against multidrug-resistant strains highlights the need for alternative non-antibiotic approaches for the treatment of V. cholerae infections. The aim of this study was to specifically examine the potential direct effect of unstimulate ...
DOI:
10.1016/j.micpath.2019.103867

91. Antibacterial and antibiofilm activity of coenzyme Q0 against Vibrio parahaemolyticus

Author:
Xiaoying Zheng; Jialu Guo; Huishan Rao; Du Guo; Yixiao Huang; Yunfeng Xu; Sen Liang; Xiaodong Xia; Chao Shi
Source:
Food control 2020 v.109 pp. 106955
ISSN:
0956-7135
Subject:
DNA; RNA; Vibrio parahaemolyticus; anti-inflammatory activity; antibiotic resistance; antibiotics; antimicrobial properties; antineoplastic activity; biofilm; cell membranes; minimum inhibitory concentration; polyacrylamide gel electrophoresis; proteins; seafoods; shrimp; stainless steel; supply chain
Abstract:
... Coenzyme Q0 (CoQ0) demonstrates antineoplastic and anti-inflammatory properties; however, its antimicrobial and antibiofilm activities against Vibrio parahaemolyticus have not been extensively examined. Thus, the aim of the current study was to investigate the antimicrobial and antibiofilm activities, along with the underlying mechanism, of CoQ0 against V. parahaemolyticus. The minimum inhibitory ...
DOI:
10.1016/j.foodcont.2019.106955

92. Antibacterial and photocatalytic activities of 5-nitroindole capped bimetal nanoparticles against multidrug resistant bacteria

Author:
Ranjith Kumar Manoharan; Shanmugam Mahalingam; Prakash Gangadaran; Young-Ho Ahn
Source:
Colloids and surfaces 2020 v.188 pp. 110825
ISSN:
0927-7765
Subject:
Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; animal pathogens; antibiotic resistance; antibiotics; antimicrobial properties; bacteria; biofilm; cell growth; cupric oxide; infectious diseases; light; membrane bioreactors; multiple drug resistance; nanoparticles; photocatalysis; scanning electron microscopy; therapeutics; wastewater treatment; zinc oxide
Abstract:
... The emergence of antibiotic resistance to commercially- available antibiotics is becoming a major health crisis worldwide. Non-antibiotic strategies are needed to combat biofilm-associated infectious diseases caused by multidrug resistant (MDR) bacterial pathogens. In this study, MBR1 was isolated from a membrane bioreactor used in wastewater treatment plants, and the resistance profile was explor ...
DOI:
10.1016/j.colsurfb.2020.110825

93. Antibacterial modification of Lyocell fiber: A review

Author:
Kevin J. Edgar; Huihui Zhang
Source:
Carbohydrate polymers 2020 v.250 pp. 116932
ISSN:
0144-8617
Subject:
additives; antibacterial properties; antibiotics; bacteria; cellulosic fibers; chemical reactions; coatings; crosslinking; fungi; hygiene; manufacturing; mixing; solvents; spinning
Abstract:
... As the most successful regenerated cellulose fiber developed in recent decades, Lyocell has attracted much attention due to its useful properties, simple manufacturing process, and recyclable solvent. However, Lyocell’s lack of antibacterial properties limits its application in medical and health fields. Antibacterial modification of Lyocell fiber can be achieved by three general approaches: physi ...
DOI:
10.1016/j.carbpol.2020.116932

94. Antibacterial nanostructures derived from oxidized sodium alginate-ZnO

Author:
L.M. Dwivedi; K. Baranwal; S. Gupta; M. Mishra; S. Sundaram; V. Singh
Source:
International journal of biological macromolecules 2020 v.149 pp. 1323-1330
ISSN:
0141-8130
Subject:
Bacillus subtilis; Cellulosimicrobium cellulans; Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus; X-ray diffraction; antibiotics; bioactive properties; guar gum; nanocomposites; nanomaterials; oxidation; particle size; scanning electron microscopy; sodium; sodium alginate; transmission electron microscopy; zinc oxide
Abstract:
... The present study describes synthesis, characterization and antibacterial application of oxidized sodium alginate (OSA)-zinc oxide (ZnO) hybrid nanostructures (OSA-ZnO). In continuation to our previous study on oxidized guar gum (OGG)-ZnO (OGG-ZnO) nanocomposite, in the present study we have chosen OSA to understand the role of polysaccharide charge type in designing the antibacterial material. Th ...
DOI:
10.1016/j.ijbiomac.2020.02.011

95. Antibacterial potential of Juglomycin A isolated from Streptomyces achromogenes, an endophyte of Crocus sativus Linn

Author:
T. Ahmad; P. Arora; Y. Nalli; A. Ali; S. Riyaz‐Ul‐Hassan
Source:
Journal of applied microbiology 2020 v.128 no.5 pp. 1366-1377
ISSN:
1364-5072
Subject:
Bacillus thuringiensis; Crocus sativus; Escherichia coli; Streptomyces achromogenes; Xanthobacter flavus; antibacterial properties; antibiotics; biofilm; endophytes; gene expression regulation; genes; minimum inhibitory concentration; models; naphthoquinones; pathogens; swimming; virulence
Abstract:
... AIM: To evaluate the antimicrobial potential of Juglomycins isolated from Streptomyces achromogenes E91CS4, an endophyte of Crocus sativus Linn. METHODS AND RESULTS: The extract from E91CS4 displayed significant antimicrobial activity against several pathogens. The endophyte was identified as S. achromogenes on by 16S ribosomal gene analysis. Chemical investigation of the extract led to the isolat ...
DOI:
10.1111/jam.14568

96. Antibacterial potential of Ni-doped zinc oxide nanostructure: comparatively more effective against Gram-negative bacteria including multi-drug resistant strains

Author:
Atanu Naskar; Sohee Lee; Kwang-sun Kim
Source:
RSC advances 2020 v.10 no.3 pp. 1232-1242
ISSN:
2046-2069
Subject:
Acinetobacter baumannii; Escherichia coli; Gram-negative bacteria; Staphylococcus aureus; Staphylococcus epidermidis; X-ray diffraction; X-ray photoelectron spectroscopy; antibacterial properties; antibiotics; genes; minimum inhibitory concentration; multiple drug resistance; nanomaterials; nickel; public health; reactive oxygen species; scanning electron microscopy; transmission electron microscopy; zinc; zinc oxide
Abstract:
... Infections by multidrug-resistant (MDR) bacteria are one of the most threatening concerns for public health. For this purpose, nanomaterials have emerged with great potential for antibacterial activity. In this paper, we report the synthesis of new Ni²⁺-doped zinc oxide (Ni-ZnO or NZO) nanostructures as targeted antibacterial agents for Gram-negative bacteria. A one-pot low-temperature solution pr ...
DOI:
10.1039/c9ra09512h

97. Antibacterial properties and cytocompatibility of biobased nanofibers of fish scale gelatine, modified polylactide, and freshwater clam shell

Author:
Dung-Yi Wu; Shan-Shue Wang; Chin-San Wu
Source:
International journal of biological macromolecules 2020 v.165 pp. 1219-1228
ISSN:
0141-8130
Subject:
Corbicula fluminea; adhesion; antibacterial properties; antibiotics; apoptosis; biocompatibility; cell cycle; cell proliferation; cell viability; clams; freshwater; gelatin; mullet; nanofibers; polylactic acid; quantitative analysis; scales (integument); shell (molluscs); tensile strength; toxicity testing
Abstract:
... We report herein new nanofibers prepared from fish scale gelatine (FSG), modified polylactide (MPLA), and a natural antibacterial agent of freshwater clam (Corbicula fluminea Estefanía) shell powder (FCSP). A preparation of FSG from Mullet scales is also described. To improve the biocompatibility and antibacterial activity of the non-woven nanofibers, MPLA/FCSP was added to enhance their antibacte ...
DOI:
10.1016/j.ijbiomac.2020.10.002

98. Antibacterial properties of a bacterial cellulose CQD-TiO2 nanocomposite

Author:
Samira Malmir; Atiyeh Karbalaei; Mehrab Pourmadadi; Javad Hamedi; Fatemeh Yazdian; Mona Navaee
Source:
Carbohydrate polymers 2020 v.234 pp. 115835
ISSN:
0144-8617
Subject:
Fourier transform infrared spectroscopy; Staphylococcus aureus; antibacterial properties; antibiotics; bandages; carbon; cellulose; fibroblasts; human cell lines; nanocomposites; nanoparticles; tensile strength; tissue repair; toxicity
Abstract:
... Antibacterial dressing can prevent the occurrence of many infections of wounds. Bacterial cellulose (BC) has the ability to carry and transfer the medicine to achieve a wound healing bandage. In this study, Carbon Quantum Dots-Titanium dioxide (CQD-TiO₂) nanoparticles (NP) were added to BC as antibacterial agents. FTIR Spectroscopy illuminated that NPs were well-bonded to BC. Interestingly, MIC te ...
DOI:
10.1016/j.carbpol.2020.115835

99. Antibacterial self-assembled nanodrugs composed of berberine derivatives and rhamnolipids against Helicobacter pylori

Author:
Yuanna Shen; Yiqing Zou; Xiaonan Chen; Pengyu Li; Yiqin Rao; Xuan Yang; Yingying Sun; Haiyan Hu
Source:
Journal of controlled release 2020 v.328 pp. 575-586
ISSN:
0168-3659
Subject:
Helicobacter pylori; animal models; antibiotic resistance; antibiotics; bacteria; berberine; biofilm; electrostatic interactions; epithelium; gastrointestinal system; hydrophilicity; hydrophobic bonding; in vitro studies; lipophilicity; mice; molecular dynamics; mucins; mucus; nanomaterials; polymers; rhamnolipids; simulation models; therapeutics
Abstract:
... The prevalence of infections with Helicobacter pylori (H. pylori) has progressively increased worldwide, which demonstrated to be closely correlated to its biofilm formation. H. pylori biofilms protect the bacteria by significantly decreasing their sensitivity to antibiotics. Moreover, H. pylori colonizes on the gastrointestinal tract epithelium which is covered by mucus layer, acting as another b ...
DOI:
10.1016/j.jconrel.2020.09.025

100. Antibacterial, Mutagenic Properties and Chemical Characterisation of Sugar Bush (Protea caffra Meisn.): A South African Native Shrub Species

Author:
McMaster Vambe; Adeyemi O. Aremu; Jude C. Chukwujekwu; Jiri Gruz; Andrea Luterová; Jeffrey F. Finnie; Johannes Van Staden
Source:
Plants 2020 v.9 no.10 pp. -
ISSN:
2223-7747
Subject:
Ames test; Enterococcus faecalis; Protea; antibacterial properties; antibiotics; branches; carboxylic acids; diarrhea; ethyl acetate; gas chromatography-mass spectrometry; herbal medicines; liquid chromatography; medicinal properties; methanol; minimum inhibitory concentration; mutagens; phenolic acids; plant extracts; sugars; tandem mass spectrometry; South Africa
Abstract:
... Protea caffra is used as a diarrhoeal remedy in South African herbal medicine, however, its pharmacological properties remain largely unknown. In the present study, extracts from different Protea caffra organs were screened against drug-sensitive and -resistant diarrhoeagenic pathogens using the microdilution assay (minimum inhibitory concentration, MIC). Twig extracts (70% methanol, MeOH) of the ...
DOI:
10.3390/plants9101331