U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication Year 2019 Remove constraint Publication Year: 2019 Subject antineoplastic agents Remove constraint Subject: antineoplastic agents Subject antioxidant activity Remove constraint Subject: antioxidant activity Subject term antineoplastic activity Remove constraint Subject term: antineoplastic activity Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
Start Over

Search

9  Search Results

1 - 9 of 9
Number of results to display per page

Search Results

1. Allium vegetables for possible future of cancer treatment

Author:
Yahya Asemani; Nasrindokht Zamani; Maryam Bayat; Zahra Amirghofran
Source:
Phytotherapy research 2019 v.33 no.12 pp. 3019-3039
ISSN:
0951-418X
Subject:
Allium; adverse effects; ajoene; antineoplastic activity; antineoplastic agents; antioxidant activity; apoptosis; cell cycle; chives; garlic; health effects assessments; ingredients; leeks; medicinal plants; metastasis; neoplasm cells; neoplasms; quercetin; shallots; signal transduction; sulfur; therapeutics; traditional medicine
Abstract:
... Natural resources such as plants are an upright curing option in treating cancers and reducing the side effects of current therapeutic modalities. Allium genus vegetables are of the most interesting herbs in restricting cancers that includes garlic, onions, leeks, chives, and shallots. These plants have been exploited in folk medicine because of their beneficial health effects in improving numerou ...
DOI:
10.1002/ptr.6490

2. Antioxidant, cytotoxicity and anti-tumor activity of Cordia dichotoma fruits accompanied with its volatile and sugar composition

Author:
Abeer Y. Ibrahim; Samah A. El-Newary; Gamil E. Ibrahim
Source:
Annals of agricultural science 2019 v.64 no.1 pp. 29-37
ISSN:
0570-1783
Subject:
Cordia dichotoma; alkaloids; alpha-phellandrene; alpha-terpineol; antineoplastic activity; antineoplastic agents; antioxidant activity; ascites; body weight; bornyl acetate; butyrates; carcinoma; catechin; chemical composition; cytotoxicity; dose response; fructose; fruit pulp; fruits; gallic acid; gas chromatography-mass spectrometry; glucose; hematologic tests; high performance liquid chromatography; ions; lethal dose 50; longevity; metals; mice; phenols; quercetin; sucrose; superoxide anion; tannins; volatile compounds
Abstract:
... The aim of the present research was to investigate the chemical composition, antioxidant and anti-tumor effects of Cordia dichotoma fruit pulp extract “CDFP-extract”. Day after intraperitoneal inoculation of Ehrlich ascites carcinoma (EAC) cells in mice, CDFP-extract was administered orally at 500 mg/kg body weight (equal to 0.10 of determined LD50) for ten consecutive days. CDFP-extract contains ...
DOI:
10.1016/j.aoas.2019.05.008

3. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

4. Changes Over the Fermentation Period in Phenolic Compounds and Antioxidant and Anticancer Activities of Blueberries Fermented by Lactobacillus plantarum

Author:
Ji‐Yeon Ryu; Hye Rim Kang; Somi Kim Cho
Source:
Journal of food science 2019 v.84 no.8 pp. 2347-2356
ISSN:
0022-1147
Subject:
2,2-diphenyl-1-picrylhydrazyl; Lactobacillus plantarum; additives; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; catechol; chlorogenic acid; epigallocatechin; ethanol; fermentation; free radicals; gallic acid; high performance liquid chromatography; human cell lines; lactic acid bacteria; malvidin; metabolites; phenol; polyphenols; protocatechuic acid; syringic acid; uterine cervical neoplasms
Abstract:
... This study determined the effects of blueberry fermentation by Lactobacillus plantarum on antioxidant and anticancer activities. The fermented blueberries extracted with 80% ethanol (FBE) showed increased superoxide dismutase‐like activity, increased scavenging of DPPH and alkyl radicals, and increased antiproliferative activity against human cervical carcinoma HeLa cells by inducing apoptosis. Se ...
DOI:
10.1111/1750-3841.14731

5. Extracts of Hypsizygus tessellatus (white var.) caps inhibited MCF-7 and MDA-MB-231 cell lines proliferation

Author:
C. I. Ukaegbu; S. R. Shah; H. A. Hamid; Z. Normaiza; O. R. Alara
Source:
Journal of food measurement & characterization 2019 v.13 no.1 pp. 368-382
ISSN:
2193-4126
Subject:
2,2-diphenyl-1-picrylhydrazyl; Hypsizygus; acetone; adverse effects; antineoplastic activity; antineoplastic agents; antioxidant activity; breast neoplasms; breasts; cell lines; chemical constituents of plants; drug therapy; ethyl acetate; free radical scavengers; hydrogen peroxide; inhibitory concentration 50; liquid chromatography; mass spectrometry; neoplasm cells
Abstract:
... Cancer management is associated with serious side-effects due to the harmful nature of radiation and chemotherapy on the body cells. These side-effects have necessitated the need for diversifying the alternative or complementary sources of cancer therapy. Natural products have been on the front line as alternative sources of anticancer agents and have attracted much attention in recent times. In t ...
DOI:
10.1007/s11694-018-9952-8

6. Inhibition of human breast cancer cells (MCF-7 cell line) growth via cell proliferation, migration, and angiogenesis by auraptene of Ferula szowitsiana root extract

Author:
Ensiyeh Charmforoshan; Ehsan Karimi; Ehsan Oskoueian; Ali Es-Haghi; Mehrdad Iranshahi
Source:
Journal of food measurement & characterization 2019 v.13 no.4 pp. 2644-2653
ISSN:
2193-4126
Subject:
2,2-diphenyl-1-picrylhydrazyl; Ferula; angiogenesis; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; breast neoplasms; caspase-3; caspase-8; cell proliferation; chemoprevention; coumarins; cytotoxicity; drug therapy; enriched foods; food industry; free radicals; functional foods; gene expression regulation; genes; human cell lines; inhibitory concentration 50; neoplasm cells; root extracts; vascular endothelial growth factor receptor-1; vascular endothelial growth factor receptor-2; Central Asia; Iran
Abstract:
... The different species of the Ferula (Apiaceae) genus are endemic in central Asia and are used as a medicinal food in Iran. The Ferula szowitsiana has been reported with anti-inflammatory, anti-hypertensive, anti-helicobacter, antileishmanial and cancer chemopreventive activities. Auraptene is one of the main coumarins from Ferula szowitsiana root. Despite the interesting biological properties of F ...
DOI:
10.1007/s11694-019-00185-6

7. Optimization of polysaccharide extraction process from grifola frondosa and its antioxidant and anti-tumor research

Author:
Xiaoyu Chen; Haiyu Ji; Xiaomeng Xu; Anjun Liu
Source:
Journal of food measurement & characterization 2019 v.13 no.1 pp. 144-153
ISSN:
2193-4126
Subject:
2,2-diphenyl-1-picrylhydrazyl; Grifola frondosa; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; human cell lines; microwave treatment; polysaccharides; raw materials; temperature; ultrasonics
Abstract:
... In order to get high yield polysaccharide from grifola frondosa, single factor experiment and an orthogonal experiment were applied to optimize the best extraction conditions. Extraction time, extraction temperature, ratio of raw material to water and auxiliary factors (microwave assisted, ultrasound assisted) were the main factors to influence the yield and purity of the extracted crude polysacch ...
DOI:
10.1007/s11694-018-9927-9

8. Phytochemical profiling, antioxidant and anticancer activities of Gastrocotyle hispida growing in Saudi Arabia

Author:
Abdelaaty A. Shahat; Syed Hidayathulla; Azmat A. Khan; Amer M. Alanazi; Osaid T. Al Meanazel; Ali S. Alqahtani; Mansour S. Alsaid; Ahmed A. Hussein
Source:
Acta tropica 2019 v.191 pp. 243-247
ISSN:
0001-706X
Subject:
2,2-diphenyl-1-picrylhydrazyl; Boraginaceae; aerial parts; antineoplastic activity; antineoplastic agents; antioxidant activity; beta-sitosterol; breast neoplasms; breasts; cell lines; chromatography; dose response; free radical scavengers; gallic acid; in vitro studies; inhibitory concentration 50; kidneys; leaves; liver; methanol; models; neoplasm cells; polyphenols; quercetin; rheumatoid arthritis; rosmarinic acid; tea; Saudi Arabia
Abstract:
... The present study aimed at isolation the phytocompounds from the aerial parts of Gastrocotyle hispida and to evaluate its antioxidant and anticancer potential using in vitro assay. Gastrocotyle hispida is belonging to the family Boraginaceae used as a refreshing drink like tea. The decoction of the leaves is diuretic and is used in the treatment of rheumatism. Phytochemical study of a methanol ext ...
DOI:
10.1016/j.actatropica.2019.01.013

9. Production and characterization of exopolysaccharides from Chlorella zofingiensis and Chlorella vulgaris with anti-colorectal cancer activity

Author:
Jianzhi Zhang; Lu Liu; Feng Chen
Source:
International journal of biological macromolecules 2019 v.134 pp. 976-983
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Chlorella vulgaris; antineoplastic activity; antineoplastic agents; antioxidant activity; cell viability; colorectal neoplasms; exopolysaccharides; human cell lines; humans; hydroxyl radicals; microalgae; molecular weight; neoplasm cells; sugars
Abstract:
... The production, physicochemical characteristics, antioxidant and antitumor activities of partial purified exopolysaccharides from Chlorella zofingiensis, Chlorella vulgaris were investigated. The final exopolysaccharides productions were 208.4, 364.3 mg/L and the average molecular weights were 2.66×104, 1.88×104 Da, respectively. Monosaccharide analysis indicating that these exopolysaccharides con ...
DOI:
10.1016/j.ijbiomac.2019.05.117