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You searched for: Publication Year 2019 Remove constraint Publication Year: 2019 Subject term 2,5-dihydroxybenzoic acid Remove constraint Subject term: 2,5-dihydroxybenzoic acid Subject term polyphenols Remove constraint Subject term: polyphenols Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

2. Metabolic Profiling of Dietary Polyphenols and Methylxanthines in Normal and Malignant Mammary Tissues from Breast Cancer Patients

Author:
María Ángeles Ávila‐Gálvez; Rocío García‐Villalba; Francisco Martínez‐Díaz; Beatriz Ocaña‐Castillo; Tamara Monedero‐Saiz; Adela Torrecillas‐Sánchez; Beatriz Abellán; Antonio González‐Sarrías; Juan Carlos Espín
Source:
Molecular nutrition & food research 2019 v.63 no.9 pp. e1801239
ISSN:
1613-4125
Subject:
2,5-dihydroxybenzoic acid; animal tissues; antineoplastic activity; breast neoplasms; breasts; caffeine; chemoprevention; epithelial cells; grape seed extract; lemons; mammary glands; metabolites; metabolomics; methylxanthines; neoplasm cells; olives; patients; polyphenols; pomegranates; resveratrol; surgery; theobromine; urine
Abstract:
... SCOPE: Dietary polyphenols may protect against breast cancer. However, it is unknown whether polyphenols reach human malignant breast tumors in molecular forms and(or) at concentrations likely to act against cancer. METHODS AND RESULTS: Ninteen breast cancer patients consumed three capsules daily from biopsy‐confirmed diagnosis to surgery (6 ± 2 days). The capsules contained pomegranate, orange, l ...
DOI:
10.1002/mnfr.201801239