Publication Year: 2018 / Subject term: DNA methylation and adipocytes / Text availability: Citation in PubAg

Author:: Qing Wang; Xiao Wang; Defang Lai; Jin Deng; Zhuang Hou; Hao Liang; Dongjun Liu
Source:: Research in veterinary science 2018 v.119 pp. 9-18
ISSN:: 0034-5288
Subject:: DNA methylation; adipocytes; apoptosis; cell proliferation; chromatin; droplets; gene expression; goats; histones; leptin; lipids; lysine; methyltransferases; stem cells; transcription (genetics)
Abstract:: ... Chromatin remodeling plays an essential role in regulating gene transcription. BIX-01294 is a specific inhibitor of histone methyltransferase G9a, which is responsible for methylation of histone H3 lysine 9 (H3K9) that can also regulate DNA methylation and chromatin remodeling. The purpose of this study was to investigate the effects of BIX-01294 on the potential of goat adipose derived stem cells ...
DOI:: 10.1016/j.rvsc.2018.05.009
: https://doi.org/10.1016/j.rvsc.2018.05.009

Author:: Soheila Rahmani; Nazila Pour Khalili; Fazlullah Khan; Shokoufeh Hassani; Elmira Ghafour-Boroujerdi; Mohammad Abdollahi
Source:: Life sciences 2018 v.214 pp. 136-144
ISSN:: 0024-3205
Subject:: DNA methylation; adipocytes; animals; bisphenol A; demethylation; endocrine-disrupting chemicals; epigenetics; estrogenic properties; fatty liver; genes; glucose; histones; homeostasis; insulin; islets of Langerhans; lipids; liver; microRNA; noninsulin-dependent diabetes mellitus; obesity; pollution; skeletal muscle; toxicity
Abstract:: ... Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes. As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects in the different organs involved in type 2 diabetes such as pancreas, liver, adip ...
DOI:: 10.1016/j.lfs.2018.10.044
: https://doi.org/10.1016/j.lfs.2018.10.044

Author:: Jie-yun Hong; Chu-gang Mei; Shi-jun Li; Hong-bao Wang; Chun-ping Zhao; Lin-sen Zan
Source:: Archives of biochemistry and biophysics 2018 v.659 pp. 1-12
ISSN:: 0003-9861
Subject:: DNA methylation; adipocytes; binding sites; cattle; gel electrophoresis; gene expression; glucose; insulin secretion; lipid metabolism; longissimus muscle; luciferase; messenger RNA; moieties; neoplasms; promoter regions; proto-oncogenes; subcutaneous fat; testes; transactivators; transcription (genetics); transferases
Abstract:: ... Sirtuin6 (SIRT6) is an ADP-ribosyltransferase and NAD⁺-dependent deacylase of acetyl groups and long-chain fatty acyl groups, and has been shown as a regulator of insulin secretion, glucose metabolism, lipid metabolism, and cancer. In this study, we determined that the bovine SIRT6 showed higher levels of mRNA expression in the testis, longissimus thoracis, and subcutaneous fat tissue. To elucidat ...
DOI:: 10.1016/j.abb.2018.09.018
: https://doi.org/10.1016/j.abb.2018.09.018

Author:: Gui-Min Zhang; Cheng-Chuang Song; Li-Juan Li; Hua He; Shu-Yue Shi; Chu-Zhao Lei; Li Zheng; Shu-Jun Peng; Yi-Ran Tian; Rui-Hua Dang; Xian-Yong Lan; Xing-Lei Qi; Hong Chen; Yong-Zhen Huang
Source:: Gene 2018 v.676 pp. 243-248
ISSN:: 0378-1119
Subject:: DNA methylation; absorption; adipocytes; beef quality; binding proteins; bisulfites; cattle; cattle breeds; cell differentiation; epigenetics; fibroblasts; gene expression; gene expression regulation; genes; genomic islands; homeostasis; hybrids; messenger RNA; metabolism; methyltransferases; muscles; neoplasms; phenotype; purebreds; quantitative polymerase chain reaction; retinoic acid; sequence analysis; therapeutics; transcription (genetics)
Abstract:: ... As an important epigenetic modification DNA methylation is catalyzed by DNA methylation transferases (DNMTs) and occurs mainly in CpG islands. DNA methylation plays an important role in regulates gene expression, cell differentiation, genetic imprinting and tumor therapy. Retinoic acid-binding proteins (RAC) is vital for the absorption, transport, metabolism and maintenance of homeostasis of retin ...
DOI:: 10.1016/j.gene.2018.07.049
: https://doi.org/10.1016/j.gene.2018.07.049

Author:: Wei Li; Renqiao Tang; Feifei Ma; Shengrong Ouyang; Zhuo Liu; Jianxin Wu
Source:: Journal of nutritional biochemistry 2018 v.59 pp. 76-83
ISSN:: 0955-2863
Subject:: DNA methylation; adipocytes; adipose tissue; animal disease models; blood glucose; drinking water; epididymis; folic acid; genes; glucose; high fat diet; insulin; insulin resistance; insulin secretion; mice; noninsulin-dependent diabetes mellitus; obesity; precipitin tests
Abstract:: ... Folic acid (FA) supplementation may protect from obesity and insulin resistance, the effects and mechanism of FA on chronic high-fat-diet-induced obesity-related metabolic disorders are not well elucidated. We adopted a genome-wide approach to directly examine whether FA supplementation affects the DNA methylation profile of mouse adipose tissue and identify the functional consequences of these ch ...
DOI:: 10.1016/j.jnutbio.2018.05.010
: https://doi.org/10.1016/j.jnutbio.2018.05.010

Author:: Yu-Hua Yang; Ru-Zhi Zhang; Sai Cheng; Bin Xu; Ting Tian; Hai-Xia Shi; Li Xiao; Ren-He Chen
Source:: Cellular reprogramming 2018 v.20 no.6 pp. 356-364
ISSN:: 2152-4998
Subject:: DNA methylation; Lentivirus; adipocytes; culture dishes; dyes; ectoderm; embryonic stem cells; epidermis (animal); hepatocytes; humans; induced pluripotent stem cells; keratinocytes; mice; staining; therapeutics; transcription factors; transfection
Abstract:: ... Induced pluripotent stem cells (iPSCs) play an important role in cell replacement therapy. Several studies have shown that keratinocytes are promising reprogrammed cells. We easily and efficiently enriched epidermal stem cells by attaching them for a limited time in culture dishes. Individual epidermal cells enriched in stem cells, which showed strong immunostaining for K15, were obtained and gene ...
DOI:: 10.1089/cell.2018.0035
: https://doi.org/10.1089/cell.2018.0035

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