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You searched for: Publication Year 2017 Remove constraint Publication Year: 2017 Subject Drosophila melanogaster Remove constraint Subject: Drosophila melanogaster
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1. AMP-activated protein kinase protects against anoxia in Drosophila melanogaster

Author:
Justin J. Evans; Chengfeng Xiao; R. Meldrum Robertson
Source:
Comparative biochemistry and physiology 2017 v.214 pp. 30-39
ISSN:
1095-6433
Subject:
AMP-activated protein kinase; Drosophila melanogaster; adenosine triphosphate; brain; coma; energy; fat body; hypoxia; models; neurons; starvation
Abstract:
... During anoxia, proper energy maintenance is essential in order to maintain neural operation. Starvation activates AMP-activated protein kinase (AMPK), an evolutionarily conserved indicator of cellular energy status, in a cascade which modulates ATP production and consumption. We investigated the role of energetic status on anoxia tolerance in Drosophila and discovered that starvation or AMPK activ ...
DOI:
10.1016/j.cbpa.2017.09.006

2. Abundant expression of somatic transposon-derived piRNAs throughout Tribolium castaneum embryogenesis

Author:
Maria Ninova; Sam Griffiths-Jones; Matthew Ronshaugen
Source:
Genome biology 2017 v.18 no.1 pp. 184
ISSN:
1474-760X
Subject:
insects; proteins; messenger RNA; loci; oocytes; Tribolium castaneum; arthropods; evolution; models; non-coding RNA; animal ovaries; embryogenesis; Drosophila melanogaster; transposons
Abstract:
... BACKGROUND: Piwi-interacting RNAs (piRNAs) are a class of short (~26–31-nucleotide) non-protein-coding RNAs expressed in the metazoan germline. The piRNA pathway in arthropods is best understood in the ovary of Drosophila melanogaster, where it acts to silence active transposable elements (TEs). Maternal loading of piRNAs in oocytes is further required for the inheritance of piRNA-mediated transpo ...
DOI:
10.1186/s13059-017-1304-1
PubMed:
28950880
PubMed Central:
PMC5613491

3. Acclimation responses to short‐term temperature treatments during early life stages causes long lasting changes in spontaneous activity of adult Drosophila melanogaster

Author:
Heidi J. MacLean; Torsten N. Kristensen; Johannes Overgaard; Jesper G. Sørensen; Simon Bahrndorff
Source:
Physiological entomology 2017 v.42 no.4 pp. 404-411
ISSN:
0307-6962
Subject:
Drosophila melanogaster; acclimation; adults; ambient temperature; cold stress; eggs; exposure duration; heat; heat tolerance; larvae; males; phenotype; pupae
Abstract:
... Ecotherms adjust their physiology to environmental temperatures. Long‐term exposures to heat or cold typically induce acclimation responses that generate directional, but reversible shifts in thermal tolerance and performance. However, less is known about how short exposure in different life stages will affect the adult phenotype. In the present study, we compared the effects of long‐term temperat ...
DOI:
10.1111/phen.12212

4. Accumulation, elimination, sequestration, and genetic variation of lead (Pb2+) loads within and between generations of Drosophila melanogaster

Author:
Elizabeth K. Peterson; Diane T. Wilson; Bernard Possidente; Phillip McDaniel; Eric J. Morley; Debra Possidente; Kurt T. Hollocher; Douglas M. Ruden; Helmut V.B. Hirsch
Source:
Chemosphere 2017 v.181 pp. 368-375
ISSN:
0045-6535
Subject:
Drosophila melanogaster; adults; atomic absorption spectrometry; eclosion; genetic variation; larvae; lead; longevity; models; phenotypic variation; progeny; pupae; quantitative trait loci; toxicity; variance
Abstract:
... We examined accumulation, sequestration, elimination, and genetic variation for lead (Pb) loads within and between generations of Drosophila melanogaster. Flies were reared in control or leaded medium at various doses and tested for their Pb loads at different stages of development (larvae, eclosion, newly-eclosed adults, and mature adults). Pb loads were tested using Inductively Coupled Plasma Ma ...
DOI:
10.1016/j.chemosphere.2017.04.091
PubMed:
28458212
PubMed Central:
PMC5533183

5. Adaptive dynamics of cuticular hydrocarbons in Drosophila

Author:
S. Rajpurohit; R. Hanus; V. Vrkoslav; E. L. Behrman; A. O. Bergland; D. Petrov; J. Cvačka; P. S. Schmidt
Source:
Journal of evolutionary biology 2017 v.30 no.1 pp. 66-80
ISSN:
1010-061X
Subject:
Drosophila melanogaster; arthropods; environmental factors; evolution; gene frequency; genes; hydrocarbons; hydrophobicity; latitude; plasticity; rearing; seasonal variation; single nucleotide polymorphism; social behavior; stress tolerance; temperature; Eastern United States
Abstract:
... Cuticular hydrocarbons (CHCs) are hydrophobic compounds deposited on the arthropod cuticle that are of functional significance with respect to stress tolerance, social interactions and mating dynamics. We characterized CHC profiles in natural populations of Drosophila melanogaster at five levels: across a latitudinal transect in the eastern United States, as a function of developmental temperature ...
DOI:
10.1111/jeb.12988
PubMed:
27718537
PubMed Central:
PMC5214518

6. Afidopyropen: New and potent modulator of insect transient receptor potential channels

Author:
Ramani Kandasamy; Damian London; Lynn Stam; Wolfgang von Deyn; Xilong Zhao; Vincent L. Salgado; Alexandre Nesterov
Source:
Insect biochemistry and molecular biology 2017 v.84 pp. 32-39
ISSN:
0965-1748
Subject:
Acyrthosiphon pisum; Drosophila melanogaster; Schistocerca americana; binding capacity; flonicamid; fruit flies; mammals; neurons; pests; pymetrozine; transient receptor potential channels
Abstract:
... The commercial insecticides pymetrozine and pyrifluquinazon control plant-sucking pests by disturbing their coordination and ability to feed. We have previously shown that these compounds act by overstimulating and eventually silencing vanilloid-type transient receptor potential (TRPV) channels, which consist of two proteins, Nanchung and Inactive, that are co-expressed exclusively in insect chord ...
DOI:
10.1016/j.ibmb.2017.03.005

7. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia

Author:
R. D. Peyser; S. M. Lanno; S. J. Shimshak; J. D. Coolon
Source:
Insect molecular biology 2017 v.26 no.6 pp. 715-720
ISSN:
0962-1075
Subject:
Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Morinda citrifolia; adults; chromosome mapping; cytochrome P-450; enzyme activity; evolution; fruit flies; genes; hexanoic acid; host plants; loci; mixed function oxidase; octanoic acid; toxicity; toxins
Abstract:
... Drosophila sechellia is a dietary specialist species of fruit fly that has evolved resistance to the toxic secondary defence compounds produced by the fruit of its preferred host plant Morinda citrifolia. The genetic basis of adult toxin resistance is the result of evolution at five loci across the genome. Genetic mapping between D. sechellia and Drosophila simulans and subsequent functional studi ...
DOI:
10.1111/imb.12329

8. Anti-aging effect of riboflavin via endogenous antioxidant in fruit fly Drosophila melanogaster

Author:
Y.-X. Zou; M.-H. Ruan; J. Luan; X. Feng; S. Chen; Zhi-Yong Chu
Source:
journal of nutrition, health & aging 2017 v.21 no.3 pp. 314-319
ISSN:
1279-7707
Subject:
Drosophila melanogaster; anti-aging properties; biomedical research; catalase; fruit flies; humans; hydrogen peroxide; longevity; manganese; oxidative stress; reproductive performance; research institutions; riboflavin; superoxide dismutase
Abstract:
... OBJECTIVES: This study investigated the effect of riboflavin on aging in Drosophila melanogaster (fruit fly). DESIGN: Experimental study. SETTING: Naval Medical Research Institute. PARTICIPANTS: Fruit fly Drosophila melanogaster. INTERVENTION: After lifelong supplement of riboflavin, the lifespan and the reproduction of fruit flies were observed. Hydrogen peroxide (H₂O₂) was used to mimic oxidativ ...
DOI:
10.1007/s12603-016-0752-8

9. Assessing the genotoxic effects of two lipid peroxidation products (4-oxo-2-nonenal and 4-hydroxy-hexenal) in haemocytes and midgut cells of Drosophila melanogaster larvae

Author:
Eşref Demir; Ricard Marcos
Source:
Food and chemical toxicology 2017 v.105 pp. 1-7
ISSN:
0278-6915
Subject:
Drosophila melanogaster; atherosclerosis; brain; comet assay; genotoxicity; hemocytes; in vivo studies; ingestion; intestines; larvae; lipid peroxidation; liver; midgut; models; mutagens; neoplasms; reactive oxygen species; risk
Abstract:
... Lipid peroxidation products can induce tissue damage and are implicated in diverse pathological conditions, including aging, atherosclerosis, brain disorders, cancer, lung and various liver disorders. Since in vivo studies produce relevant information, we have selected Drosophila melanogaster as a suitable in vivo model to characterise the potential risks associated to two lipid peroxidation produ ...
DOI:
10.1016/j.fct.2017.03.036

10. Assessment of genotoxic and antigenotoxic activities of artepillin C in somatic cells of Drosophila melanogaster

Author:
Carmem Regine Faleiro Rodrigues; Luciana Ciarelli Plentz; Mariana do Amaral Flores; Rafael Rodrigues Dihl; Mauricio Lehmann
Source:
Food and chemical toxicology 2017 v.101 pp. 48-54
ISSN:
0278-6915
Subject:
DNA; DNA damage; DNA repair; Drosophila melanogaster; crossing; cytochrome P-450; enzymes; ethyl methanesulfonate; genotoxicity; mitomycin; mutagenicity; propolis; somatic cells; somatic mutation; toxicology
Abstract:
... The significant contents of artepillin C (AC) in green propolis have prompted research on the biological activities of the compound. The present study evaluated the activity of this phenolic compound on DNA, assessing its genotoxic and antigenotoxic potentials in the somatic mutation and recombination test in Drosophila melanogaster. The standard (ST) and high-bioactivation (HB) crosses were used ...
DOI:
10.1016/j.fct.2017.01.005

11. Assessment of the carcinogenic potential of high intense-sweeteners through the test for detection of epithelial tumor clones (warts) in Drosophila melanogaster

Author:
Mirley Alves Vasconcelos; Priscila Capelari Orsolin; Rosiane Gomes Silva-Oliveira; Júlio César Nepomuceno; Mário Antônio Spanó
Source:
Food and chemical toxicology 2017 v.101 pp. 1-7
ISSN:
0278-6915
Subject:
Drosophila melanogaster; aspartame; blood glucose; clones; doxorubicin; epithelium; females; glycosides; larvae; males; obesity; reverse osmosis; saccharin; steviol; sucralose; sugars; sweetness; toxicology; warts
Abstract:
... High intensity-sweeteners (HIS) are natural or synthetic substances, sweeter than sugar, providing sweetness without calories. Sweeteners are mainly used as an aid in losing weight, preventing obesity and controlling blood sugar levels for diabetics. The objective of this study was to evaluate the carcinogenic potential of the sweeteners aspartame, sucralose, sodium saccharin and steviol glycoside ...
DOI:
10.1016/j.fct.2016.12.028

12. Azadirachtin impact on mate choice, female sexual receptivity and male activity in Drosophila melanogaster (Diptera: Drosophilidae)

Author:
N. Aribi; M.C. Oulhaci; S. Kilani-Morakchi; J.C. Sandoz; L. Kaiser; B. Denis; D. Joly
Source:
Pesticide biochemistry and physiology 2017 v.143 pp. 95-101
ISSN:
0048-3575
Subject:
Azadirachta indica; Drosophila melanogaster; adults; azadirachtin; botanical pesticides; female fertility; females; insecticidal properties; larvae; lethal dose 50; males; mating behavior; mechanism of action; models; probability; reproductive behavior; spermatheca; spermatozoa; ventral receptacle
Abstract:
... Azadirachtin, a neem compound (Azadirachta indica) with medical and anti-insect properties, is one the most successful botanical pesticides in agricultural use. However, its controversial impact on non-targeted species and its mechanism of action need to be clarified. In addition, Azadirachtin impact on pre- and post-mating traits remains largely undocumented. The current study examined the effect ...
DOI:
10.1016/j.pestbp.2017.09.002

13. Azadirachtin induced larval avoidance and antifeeding by disruption of food intake and digestive enzymes in Drosophila melanogaster (Diptera: Drosophilidae)

Author:
Radia Bezzar-Bendjazia; Samira Kilani-Morakchi; Ferdenache Maroua; Nadia Aribi
Source:
Pesticide biochemistry and physiology 2017 v.143 pp. 135-140
ISSN:
0048-3575
Subject:
Azadirachta indica; Drosophila melanogaster; alpha-amylase; azadirachtin; botanical insecticides; carboxylic ester hydrolases; chitinase; food intake; insecticidal properties; insects; instars; integrated pest management; larvae; lethal dose 50; proteinases; sublethal effects; trees
Abstract:
... Botanical insecticides are a promising alternative to reduce the harmful effects of synthetic chemicals. Among the botanical biopesticides, azadirachtin obtained from the Indian neem tree Azadirachta indica A. Juss. (Meliaceae) is probably the biorational insecticide with greatest agriculture use nowadays due to its broad insecticide activity. The current study, evaluated the lethal and sublethal ...
DOI:
10.1016/j.pestbp.2017.08.006

14. Biochemical characterization of a new mitochondrial transporter of dephosphocoenzyme A in Drosophila melanogaster

Author:
Angelo Vozza; Francesco De Leonardis; Eleonora Paradies; Anna De Grassi; Ciro Leonardo Pierri; Giovanni Parisi; Carlo Marya Thomas Marobbio; Francesco Massimo Lasorsa; Luigina Muto; Loredana Capobianco; Vincenza Dolce; Susanna Raho; Giuseppe Fiermonte
Source:
Biochimica et biophysica acta 2017 v.1858 no.2 pp. 137-146
ISSN:
0005-2728
Subject:
Drosophila melanogaster; Escherichia coli; Saccharomyces cerevisiae; adenosine diphosphate; alternative splicing; biochemical pathways; carbon; cytosol; enzymes; fruit flies; genes; humans; metabolism; mitochondria; mitochondrial membrane; phylogeny
Abstract:
... CoA is an essential cofactor that holds a central role in cell metabolism. Although its biosynthetic pathway is conserved across the three domains of life, the subcellular localization of the eukaryotic biosynthetic enzymes and the mechanism behind the cytosolic and mitochondrial CoA pools compartmentalization are still under debate. In humans, the transport of CoA across the inner mitochondrial m ...
DOI:
10.1016/j.bbabio.2016.11.006

15. Bloom syndrome helicase in meiosis: Pro‐crossover functions of an anti‐crossover protein

Author:
Talia Hatkevich; Jeff Sekelsky
Source:
BioEssays 2017 v.39 no.9 pp. -
ISSN:
0265-9247
Subject:
Arabidopsis thaliana; Caenorhabditis elegans; DNA repair; Drosophila melanogaster; Mus musculus; Saccharomyces cerevisiae; chromosome segregation; enzyme activity; genome; meiosis; mitosis; models; probability
Abstract:
... The functions of the Bloom syndrome helicase (BLM) and its orthologs are well characterized in mitotic DNA damage repair, but their roles within the context of meiotic recombination are less clear. In meiotic recombination, multiple repair pathways are used to repair meiotic DSBs, and current studies suggest that BLM may regulate the use of these pathways. Based on literature from Saccharomyces ce ...
DOI:
10.1002/bies.201700073
PubMed:
28792069
PubMed Central:
PMC5577929

16. CRISPR/Cas9 mediated G4946E substitution in the ryanodine receptor of Spodoptera exigua confers high levels of resistance to diamide insecticides

Author:
Yayun Zuo; Hui Wang; Yanjun Xu; Jianlei Huang; Shuwen Wu; Yidong Wu; Yihua Yang
Source:
Insect biochemistry and molecular biology 2017 v.89 pp. 79-85
ISSN:
0965-1748
Subject:
Chilo suppressalis; Drosophila melanogaster; Plutella xylostella; Spodoptera exigua; Tuta absoluta; calcium; cyantraniliprole; death; flubendiamide; gene editing; genetic background; homozygosity; insects; ions; muscle contraction; mutation; paralysis; pests; ryanodine receptors
Abstract:
... Diamide insecticides selectively activate insect ryanodine receptors (RyRs), inducing uncontrolled release of calcium ions, and causing muscle contraction, paralysis and eventually death. The RyRG4946E substitution associated with diamide resistance has been identified in three lepidopteran pests, Plutella xylostella, Tuta absoluta and Chilo suppressalis. Recently, the T. absoluta RyRG4946V mutati ...
DOI:
10.1016/j.ibmb.2017.09.005

17. Can competition be superior to parasitism for biological control? The case of spotted wing Drosophila (Drosophila suzukii), Drosophila melanogaster and Pachycrepoideus vindemmiae

Author:
Tina Dancau; Tanya L. M. Stemberger; Peggy Clarke; David R. Gillespie
Source:
Biocontrol science and technology 2017 v.27 no.1 pp. 3-16
ISSN:
1360-0478
Subject:
Drosophila melanogaster; Drosophila suzukii; Pachycrepoideus vindemmiae; adults; biological control; cages; females; oviposition; parasitism; parasitoids; progeny; pupation
Abstract:
... Drosophila suzukii and Drosophila melanogaster coexist with different but overlapping resource use in the field. When forced to completely or partially share resources in the laboratory, D. melanogaster outcompetes D. suzukii . Adult D. suzukii and D. melanogaster females were allowed to compete for access to a common oviposition resource in pairwise and population scale experiments. We tracked th ...
DOI:
10.1080/09583157.2016.1241982

18. Cells on the move: Modulation of guidance cues during germ cell migration

Author:
Girish Deshpande; Justinn Barr; Offer Gerlitz; Lyubov Lebedeva; Yulii Shidlovskii; Paul Schedl
Source:
Fly 2017 v.11 no.3 pp. 200-207
ISSN:
1933-6942
Subject:
ABC transporters; Drosophila melanogaster; biochemical pathways; cell movement; chemoattractants; cholesterol; germ cells; gonads; isoprenoids; laboratories; ligands; light; mesoderm; midgut; migratory behavior; stem cells; travel
Abstract:
... In Drosophila melanogaster the progenitors of the germ-line stem cells, the primordial germ cells (PGCs) are formed on the outside surface of the early embryo, while the somatic gonadal precursor cells (SGPs) are specified during mid-embryogenesis. To form the primitive embryonic gonad, the PGCs travel from outside of the embryo, across the mid-gut and then migrate through the mesoderm to the SGPs ...
DOI:
10.1080/19336934.2017.1304332
PubMed:
28300473
PubMed Central:
PMC5552272

19. Cellular aspects of gonadal atrophy in Drosophila P-M hybrid dysgenesis

Author:
Natalia V. Dorogova; Elena Us. Bolobolova; Lyudmila P. Zakharenko
Source:
Developmental biology 2017 pp. -
ISSN:
0012-1606
Subject:
Drosophila melanogaster; atrophy; cell death; electron microscopy; embryogenesis; germ cells; gonads; hybrid dysgenesis; imagos; mitochondria; progeny; screening; temperature
Abstract:
... Gonadal atrophy is the most typical and dramatic manifestation of intraspecific hybrid dysgenesis syndrome leading to sterility in Drosophila melanogaster dysgenic progeny. The P-M system of hybrid dysgenesis is primarily associated with germ cell degeneration during the early stages of Drosophila embryonic development at elevated temperatures. In the present study, we have defined the phase of ge ...
DOI:
10.1016/j.ydbio.2017.02.020

20. Chemical composition and toxicological evaluation of Hyptis suaveolens (L.) Poiteau (LAMIACEAE) in Drosophila melanogaster and Artemia salina

Author:
J.W.A. Bezerra; A.R. Costa; M.A.P. da Silva; M.I. Rocha; A.A. Boligon; J.B.T. da Rocha; L.M. Barros; J.P. Kamdem
Source:
South African journal of botany 2017 v.113 pp. 437-442
ISSN:
0254-6299
Subject:
Artemia salina; Drosophila melanogaster; Hyptis suaveolens; acute toxicity; air; beta-caryophyllene; caffeic acid; chemical composition; essential oils; geotaxis; high performance liquid chromatography; ingestion; leaves; lethal concentration 50; sabinene; spathulenol; traditional medicine; volatilization
Abstract:
... Hyptis suaveolens (L.) Poiteau, known as “Bamburral” is a plant widely used in Brazilian folk medicine, however, there are no toxicological studies to ascertain its safety. Thus, we aimed to investigate the phytochemical and toxic effects of essential oil and infusion of the dry leaves of H. suaveolens in Drosophila melanogaster and Artermia salina. The chemical composition of the essential oil wa ...
DOI:
10.1016/j.sajb.2017.10.003