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You searched for: Publication Year 2017 Remove constraint Publication Year: 2017 Subject glucosides Remove constraint Subject: glucosides Subject lignans Remove constraint Subject: lignans Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense

Author:
Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
Source:
Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
ISSN:
1477-2213
Subject:
2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
DOI:
10.1080/10286020.2016.1234456

2. Bioactive Glycosides from the Twigs of Litsea cubeba

Author:
Wang Ling-Yan; Chen Ming-Hua; Wu Jiang; Sun Hua; Liu Wei; Qu Yu-Hong; Li Yan-Cheng; Wu Yu-Zhuo; Li Rui; Zhang Dan; Wang Su-Juan; Lin Sheng
Source:
Journal of natural products 2017 v.80 no.6 pp. 1808-1818
ISSN:
1520-6025
Subject:
Litsea cubeba; X-ray diffraction; air drying; branches; circular dichroism spectroscopy; glucosides; human cell lines; inhibitory concentration 50; lignans; medicinal plants; nuclear magnetic resonance spectroscopy
Abstract:
... The air-dried twigs of Litsea cubeba, a traditional Chinese medicinal tree, afforded 10 new aromatic glycosides (1–10) and 26 known analogues. Their structures were assigned by extensive 1D and 2D NMR experiments, and the absolute configurations were resolved by chemical methods, electronic circular dichroism, specific rotation, and X-ray crystallographic analysis. Compound 4 is the first example ...
DOI:
10.1021/acs.jnatprod.6b01189

3. Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy

Author:
Anna Stojakowska; Janusz Malarz
Source:
Phytochemistry letters 2017 v.19 pp. 7-11
ISSN:
1874-3900
Subject:
Lactuca; caffeic acid; callus culture; chlorogenic acid; glucosides; lignans; sesquiterpenoid lactones
Abstract:
... A callus culture of Lactuca aculeata, except for commonly distributed caffeic acid derivatives typically found in the Asteraceae family (chlorogenic acid, methyl caffeate, 1,5- dicaffeoylquinic acid), yielded bioactive lignans: (+)-5-methoxybalanophonin, syringaresinol, (+)-balanophonin-9-O-β-glucopyranoside, (+) buddlenol A, (−)-dihydrodehydrodiconiferyl alcohol-4-O-β-glucopyranoside and (−)-dihy ...
DOI:
10.1016/j.phytol.2016.11.003

4. Chemical Composition and Immuno‐Modulatory Effects of Urtica dioica L. (Stinging Nettle) Extracts

Author:
Marina Francišković; Raquel Gonzalez‐Pérez; Dejan Orčić; Fermín Sánchez de Medina; Olga Martínez‐Augustin; Emilija Svirčev; Nataša Simin; Neda Mimica‐Dukić
Source:
Phytotherapy research 2017 v.31 no.8 pp. 1183-1191
ISSN:
0951-418X
Subject:
chemoattractants; kaempferol; secretion; Urtica dioica; chemokine CCL2; glucosides; intestinal mucosa; dietary supplements; liquid chromatography; protective effect; isoquercitrin; rutin; oncogenes; phytopharmaceuticals; humans; linoleate 13S-lipoxygenase; aerial parts; lignans; immune response; chemical composition; monocytes; phenolic acids; inflammation; tandem mass spectrometry; prostaglandin synthase
Abstract:
... The purpose of this work was to determine the chemical profile of stinging nettle and to provide an insight into the mechanisms by which it ameliorates the immune response. Qualitative and quantitative liquid chromatography tandem mass spectrometry analyses indicated that phenolic acids (5‐O‐caffeoylquinic acid as dominant) and flavonol glycosides (rutin, isoquercitrin, and kaempferol 3‐O‐glucosid ...
DOI:
10.1002/ptr.5836

5. Comparative analysis of the in-vitro antioxidant activity and bioactive compounds of flaxseed in China according to variety and geographical origin

Author:
Qianchun Deng; Xiao Yu; Fangli Ma; Jiqu Xu; Fenghong Huang; Qingde Huang; Feng Sheng
Source:
International journal of food properties 2017 v.20 no.sup3 pp. S2708
ISSN:
1094-2912
Subject:
2,2-diphenyl-1-picrylhydrazyl; alpha-linolenic acid; antioxidant activity; antioxidants; bioactive compounds; chemometrics; glucosides; lignans; linseed; p-coumaric acid; phytosterols; principal component analysis; provenance; syringic acid; China
Abstract:
... The present study aimed to use a chemometric study to compare the in-vitro antioxidant activities and bioactive compounds of flaxseed based on the variety and geographical origins, and further explore the specific components constructed the endogenous antioxidant system of flaxseed in China. The differential contents of α-linolenic acid (35.83–58.91%), lignans (11.37–33.31 mg/g), total phenolic ac ...
DOI:
10.1080/10942912.2017.1402029

6. Effects of photoperiod regimes and ultraviolet-C radiations on biosynthesis of industrially important lignans and neolignans in cell cultures of Linum usitatissimum L. (Flax)

Author:
Sumaira Anjum; Bilal Haider Abbasi; Joël Doussot; Alain Favre-Réguillon; Christophe Hano
Source:
Journal of photochemistry and photobiology 2017 v.167 pp. 216-227
ISSN:
1011-1344
Subject:
Linum usitatissimum; alcohols; antioxidant activity; bioactive compounds; biomarkers; biosynthesis; cell culture; flavonoids; flax; glucosides; lignans; medicinal properties; photoperiod; reversed-phase high performance liquid chromatography; ultraviolet radiation
Abstract:
... Lignans and neolignans are principal bioactive components of Linum usitatissimum L. (Flax), having multiple pharmacological activities. In present study, we are reporting an authoritative abiotic elicitation strategy of photoperiod regimes along with UV-C radiations. Cell cultures were grown in different photoperiod regimes (24h–dark, 24h–light and 16L/8D h photoperiod) either alone or in combinat ...
DOI:
10.1016/j.jphotobiol.2017.01.006

7. Furofuran lignan glucosides from the leaves of Vitex negundo var. cannabifolia

Author:
Yue-Ting Li; Man-Man Li; Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dao-Ran Pang; Jiao Zheng; Yun-Fang Zhao; Peng-Fei Tu; Jun Li
Source:
Natural product research 2017 v.31 no.8 pp. 918-924
ISSN:
1478-6427
Subject:
Vitex negundo; glucosides; inhibitory concentration 50; leaves; lignans; nitric oxide; spectral analysis; spectroscopy
Abstract:
... Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3 – 6), were isolated from the leaves of Vitex negundo var. cannabifolia . The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC ...
DOI:
10.1080/14786419.2016.1255887

8. Kinetics of the incorporation of the main phenolic compounds into the lignan macromolecule during flaxseed development

Author:
Aina Ramsay; Ophélie Fliniaux; Anthony Quéro; Roland Molinié; Hervé Demailly; Christophe Hano; Christian Paetz; Albrecht Roscher; Eric Grand; José Kovensky; Bernd Schneider; François Mesnard
Source:
Food chemistry 2017 v.217 pp. 1-8
ISSN:
0308-8146
Subject:
alkaline hydrolysis; coumaric acids; developmental stages; flavonoids; flax; glucosides; high performance liquid chromatography; lignans; linseed; nuclear magnetic resonance spectroscopy; seed development
Abstract:
... The main flax lignan, secoisolariciresinol diglucoside, is stored in a macromolecule containing other ester-bound phenolic compounds. In this study, NMR and HPLC-UV analyses were performed on flaxseeds harvested at different developmental stages to identify and quantify the main phenolic compounds produced during seed development. Extraction was carried out with or without alkaline hydrolysis to d ...
DOI:
10.1016/j.foodchem.2016.08.039

9. Neolignan and megastigmane glucosides from the aerial parts of Isodon japonicus with cell protective effects on BaP-induced cytotoxicity

Author:
Takahiro Matsumoto; Seikou Nakamura; Souichi Nakashima; Tomoe Ohta; Keiko Ogawa; Masashi Fukaya; Junko Tsukioka; Tomohiro Hasei; Tetsushi Watanabe; Hisashi Matsuda
Source:
Phytochemistry 2017 v.137 pp. 101-108
ISSN:
0031-9422
Subject:
aerial parts; chemical structure; cytotoxicity; glucosides; lignans; nuclear magnetic resonance spectroscopy; protective effect; spectral analysis; Japan
Abstract:
... Six neolignan glucosides, named isodonosides I–VI, and a megastigmane glucoside named isodonmegastigmane I, were isolated together with 15 known compounds from the methanolic extract of aerial parts of Isodon japonicus cultivated in Tokushima, Japan. The chemical structures of the compounds were elucidated based on their MS and NMR spectroscopic analysis. The absolute configurations of the neolign ...
DOI:
10.1016/j.phytochem.2017.02.007

10. A New Insecticidal Lignan Glucoside from Galium verum

Author:
Jia Chen; Chun-Chao Zhao; Jian-Hua Shao; Ju-Di Fan; Xu-Hua Huang
Source:
Chemistry of natural compounds 2017 v.53 no.4 pp. 626-628
ISSN:
0009-3130
Subject:
Galium verum; Helicoverpa armigera; Scorpiones; chemical structure; glucosides; insecticidal properties; lignans; mortality; poisoning; scorpion venoms; spectral analysis; stomach; toxicity
Abstract:
... A new lignan glucoside, galiveroside A (1), and seven known compounds (2–8), were isolated from Galium verum L. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses. Compound 1, at the concentration of 5 mg/mL, showed insecticide activity to 3 age cotton bollworm with a mortality of 16.3% through stomach poisoning. When combined with a recombinant scorpion toxin rLqh ...
DOI:
10.1007/s10600-017-2075-3

11. A New Lignan Glucoside from Cyclea racemosa

Author:
Jian-Hua Shao; Xue-Wei Zhang; Zi-Ling Dong; Si-Hui Li; Ben-Jie Miao; Ke-Zhi Cheng
Source:
Chemistry of natural compounds 2017 v.53 no.6 pp. 1025-1027
ISSN:
0009-3130
Subject:
Cyclea; chemical structure; glucosides; lignans; spectral analysis
Abstract:
... A new lignan glucoside 1, along with two known lignans (2, 3), was isolated from Cyclea racemosa Oliv. Its structure was elucidated as (+)-7′-methoxylariciresinol 4-O-β-D-glucopyranoside on the basis of extensive spectroscopic analyses. ...
DOI:
10.1007/s10600-017-2193-y

12. New Neolignan Glucoside and New Biphenyl Ether Lignan from the Fruits of Cordia latifolia

Author:
M. Fatima; B. S. Siddiqui; S. Begum
Source:
Chemistry of natural compounds 2017 v.53 no.3 pp. 432-435
ISSN:
0009-3130
Subject:
4-hydroxybenzoic acid; Cordia; benzoic acid; biphenyl; chemistry; cinnamic acid; fruits; glucosides; lignans; nuclear magnetic resonance spectroscopy; rosmarinic acid; vanillic acid
Abstract:
... One new neolignan glucoside (1) and one new biphenyl ether lignan (2) along with seven known compounds, p-hydroxybenzoic acid, rosmarinic acid, 3,4-dihydroxybenzoic acid, benzoic acid, 5-acetoxymethyl-2-furaldehyde, vanillic acid, and 5,5′-oxybis(5-methylene-2-furaldehyde), were isolated from the fruits of Cordia latifolia. The structures of 1 and 2 were elucidated as 9′-hydroxy-3,5′-dimethoxy-4′, ...
DOI:
10.1007/s10600-017-2016-1

13. Nine new compounds from the root bark of Lycium chinense and their α-glucosidase inhibitory activity

Author:
Ya-Nan Yang; Ya-Wen An; Zhi-Lai Zhan; Jing Xie; Jian-Shuang Jiang; Zi-Ming Feng; Fei Ye; Pei-Cheng Zhang
Source:
RSC advances 2017 v.7 no.2 pp. 805-812
ISSN:
2046-2069
Subject:
Lycium chinense; acarbose; alpha-glucosidase; bark; cortex; enzyme inhibition; enzyme inhibitors; fruits; glucosides; inhibitory concentration 50; lignans; naphthalene; nuclear magnetic resonance spectroscopy; sesquiterpenoids; shrubs; spectral analysis
Abstract:
... Lycium chinense Mill. is a deciduous shrub in the Solanaceae family that is known for its fruits (Lycii fructus) and root bark (Lycii cortex). In our ongoing search for α-glucosidase inhibitors from the root bark of L. chinense, lyciumflavane A, one new flavane with an unusual benzofuran unit, one new amide possessing a naphthalene skeleton, one new sesquiterpene, three new lignan glucosides, and ...
DOI:
10.1039/c6ra24751b

14. Prenylated flavonol glycosides from Epimedium grandiflorum: Cytotoxicity and evaluation against inflammation and metabolic disorder

Author:
Fazila Zulfiqar; Shabana I. Khan; Samir A. Ross; Zulfiqar Ali; Ikhlas A. Khan
Source:
Phytochemistry letters 2017 v.20 pp. 160-167
ISSN:
1874-3900
Subject:
Epimedium grandiflorum; cytotoxicity; flavonols; glucosides; icariin; inducible nitric oxide synthase; inflammation; lignans; metabolic diseases; methanol; neoplasms; norisoprenoids; nuclear magnetic resonance spectroscopy; sesquiterpenoids; sugars; transcription factor NF-kappa B
Abstract:
... Two new prenylated flavonol glycosides, epimedigrandiosides A and B (1 and 2), and 28 previously known compounds including prenylated flavonol derivatives, flavonol glycoside, megastigmanes, phenyl alkanoids, sesquiterpenoid glycoside, lignan, and hexene glucoside were isolated from the methanol extract of Epimedium grandiflorum. Structure elucidation was achieved by means of spectroscopic and spe ...
DOI:
10.1016/j.phytol.2017.04.027

15. Specialized metabolites from the aerial parts of Centaurea polyclada DC.

Author:
Serdar Demir; Canan Karaalp; Erdal Bedir
Source:
Phytochemistry 2017 v.143 pp. 12-18
ISSN:
0031-9422
Subject:
Centaurea; aerial parts; chemical degradation; flavonoids; flora; glucosides; lignans; mass spectrometry; metabolites; nuclear magnetic resonance spectroscopy; sesquiterpenoid lactones; spectral analysis; Turkey (country)
Abstract:
... The genus Centaurea L. (Asteraceae) is represented by 200 taxa in the flora of Turkey and several Centaurea species are used as herbal remedies against different conditions. Previous phytochemical investigations on this genus generally revealed the isolation of sesquiterpene lactones and flavonoid derivatives. In our continuous search on Centaurea genus, a phytochemical study was performed on Cent ...
DOI:
10.1016/j.phytochem.2017.07.002

16. Structures of minor glucosides from the Far Eastern high-mountain endemic plant Ligularia alticola Worosch. Screening of bioactivity for some glycosides from L. alticola

Author:
Alexandra S. Silchenko; Ludmila P. Ponomarenko; Anatoly I. Kalinovsky; Dmitrii V. Berdyshev; Sergey A. Avilov; Pelageya V. Andryjaschenko; Ekaterina G. Lyakhova; Alexandra S. Kuzmich; Natalia A. Terentieva; Peter G. Gorovoy
Source:
Phytochemistry letters 2017 v.20 pp. 234-238
ISSN:
1874-3900
Subject:
Escherichia coli; Ligularia; Yersinia pseudotuberculosis; aerial parts; biofilm; cytotoxicity; glucosides; indigenous species; lignans; macrophages; neoplasms; nuclear magnetic resonance spectroscopy; plants (botany); screening; sesquiterpenoids; stereochemistry
Abstract:
... Two new minor eremophilane-type sesquiterpene glucosides, alticolosides H (1) and I (2) along with known earlier lignan glucosides (−)-pinoresinol-4′-O-β-d-glucoside, plucheoside D1 and tortoside F were isolated from aerial parts of the endemic Far Eastern species Ligularia alticola Worosch. (Family Asteraceae). Structures of the glycosides were elucidated by 2D NMR spectroscopy and HRESIMS. The a ...
DOI:
10.1016/j.phytol.2017.05.011

17. Trends in accumulation of pharmacologically important antioxidant-secondary metabolites in callus cultures of Linum usitatissimum L.

Author:
Sumaira Anjum; Bilal Haider Abbasi; Christophe Hano
Source:
Plant cell, tissue, and organ culture 2017 v.129 no.1 pp. 73-87
ISSN:
0167-6857
Subject:
Linum usitatissimum; alcohols; antioxidant activity; benzyladenine; biomass; callus; callus culture; explants; flavonoids; flax; glucosides; high performance liquid chromatography; human health; leaves; lignans; naphthaleneacetic acid; neoplasms; secondary metabolites; thidiazuron
Abstract:
... Linum usitatissimum: L. is well-known for production of pharmacologically important secondary metabolites. Due to their tremendous beneficial effects on human health, these compounds are receiving greater attention throughout the World, especially in the treatment of various types of cancers. In present study, we have developed an efficient protocol for production of lignans like secoisolariciresi ...
DOI:
10.1007/s11240-016-1158-3

18. Two new lignan-iridoid glucoside diesters from the leaves of Vaccinium bracteatum and their relative and absolute configuration determination by DFT NMR and TDDFT-ECD calculation

Author:
Yong-Mei Ren; Chang-Qiang Ke; Attila Mándi; Tibor Kurtán; Chunping Tang; Sheng Yao; Yang Ye
Source:
Tetrahedron 2017 pp. -
ISSN:
0040-4020
Subject:
Vaccinium bracteatum; biochemical pathways; chemical reactions; chemical structure; circular dichroism spectroscopy; glucosides; iridoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Two new lignan-iridoid glucoside diesters (2 and 3), together with their putative biosynthetic precursor 10-O-trans-caffeoyl-6α-hydroxyl-dihydromonotropein (1), were characterized from the leaves of Vaccinium bracteatum. Their planar structures and relative configuration were elucidated by spectroscopic measurements and DFT C NMR calculations, and their absolute configurations were determined by t ...
DOI:
10.1016/j.tet.2017.04.040