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You searched for: Publication Year 2017 Remove constraint Publication Year: 2017 Subject glucosides Remove constraint Subject: glucosides Subject spectral analysis Remove constraint Subject: spectral analysis Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. 2-Carboxy-dihydrostilbene and flavan glycosides from Desmodium heterocarpon

Author:
Poolsak Sahakitpichan; Piyawadee Chadmuk; Nitirat Chimnoi; Anucha Namsa-aid; Somsak Ruchirawat; Tripetch Kanchanapoom
Source:
Phytochemistry letters 2017 v.19 pp. 94-97
ISSN:
1874-3900
Subject:
Desmodium heterocarpon; flavonoids; glucosides; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... A new 2-carboxy-dihydrostilbene glucoside, 2-carboxy-3,5,4′-trihydroxydihydrostilbene 3-O-β-d-glucopyranoside (1) and a new flavan diglycoside, (2S)-5,7,4′-trihydroxyflavan 7-O-β-d-apiofuranosyl-(1→6)-O-β-d-glucopyranoside (3) were isolated from the aerial portion of Thai origin Desmodium heterocarpon together with five known compounds, lunularic acid 4′-O-β-d-glucopyranoside (2), vitexin (4), iso ...
DOI:
10.1016/j.phytol.2016.12.011

2. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense

Author:
Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
Source:
Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
ISSN:
1477-2213
Subject:
2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
DOI:
10.1080/10286020.2016.1234456

3. Apocynin derivatives from Iris tectorum

Author:
Chun-Lei Zhang; Guo-Ru Shi; Yan-Fei Liu; Yan Wang; Ruo-Yun Chen; De-Quan Yu
Source:
Journal of Asian natural products research 2017 v.19 no.2 pp. 128-133
ISSN:
1477-2213
Subject:
Iris (Iridaceae); chemical derivatives; chemical structure; glucosides; rhizomes; spectral analysis
Abstract:
... Phytochemical investigation of the rhizomes of Iris tectorum resulted in the isolation and characterization of three new apocynin derivatives, apocynin-4-O- β -D-(6′-O-syringyl)glucopyranoside (1), scrophenoside C-7-ethyl ether (2 , 3), together with a new naturally occurring compound but known by synthesis, apocynin-4-O- β -D-xylopyranoside (4), and five known ones (5–9). Their structures were el ...
DOI:
10.1080/10286020.2016.1268128

4. Cornusides A–O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis

Author:
Xian-Sheng Ye; Jun He; Yung-Chi Cheng; Lei Zhang; Hao-Yi Qiao; Xue-Ge Pan; Jia Zhang; Shu-Na Liu; Wei-Ku Zhang; Jie-Kun Xu
Source:
Journal of natural products 2017 v.80 no.12 pp. 3103-3111
ISSN:
1520-6025
Subject:
Cornus officinalis; chemical structure; fruits; glucosides; human cell lines; inhibitory concentration 50; iridoid glycosides; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Fifteen new and rare iridoid glucoside dimers, cornusides A–O (1–15), and 10 known iridoid glucosides (16–25) were isolated from the fruit of Cornus officinalis. These new chemical structures were established through spectroscopic analysis (UV, IR, HRESIMS, 1D and 2D NMR). Compounds 1–25 were tested for their inhibitory activities by measuring IL-6-induced STAT3 promoter activity in HepG2 cells, a ...
DOI:
10.1021/acs.jnatprod.6b01127

5. Divaccinosides A-D, four rare iridoid glucosidic truxillate esters from the leaves of Vaccinium bracteatum

Author:
Yong-Mei Ren; Chang-Qiang Ke; Chunping Tang; Sheng Yao; Yang Ye
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
Vaccinium bracteatum; X-ray diffraction; chemical structure; cycloaddition reactions; esters; glucosides; leaves; spectral analysis
Abstract:
... Divaccinosides A-D (1-4), four rare iridoid glucoside cyclodimers in the truxillate forms, were characterized from the leaves of Vaccinium bracteatum. They were presumably biosynthesized from two known iridoid glucoside monomers, vaccinoside (5) and 10-O-trans-p-coumaroyl-6α-hydroxyl-dihydromonotropein (6), via a [2+2] cycloaddition reaction. The structures of the new compounds were established by ...
DOI:
10.1016/j.tetlet.2017.05.013

6. Eremophilane-type glucosides from the leaves of Ligularia calthifolia Maxim

Author:
Ludmila P. Ponomarenko; Sophia D. Ermolaeva; Roman V. Doudkin; Sergey A. Dyshlovoy; Petr G. Gorovoy
Source:
Phytochemistry letters 2017 v.21 pp. 264-268
ISSN:
1874-3900
Subject:
Ligularia; glucose; glucosides; humans; leaves; neoplasm cells; prostatic neoplasms; spectral analysis
Abstract:
... Three eremophilane-type glucosides (1–3) along with three known congeners alticolosides A, B and D (4–6) have been isolated from the leaves of Ligularia calthifolia Maxim. (Asteraceae). The structures of 1–3 have been elucidated by spectroscopic analysis as well as by chemical transformations. A distinctive feature of the compounds 1–3 is the presence of an acetyl group in the glucose residues. Th ...
DOI:
10.1016/j.phytol.2017.07.013

7. Four new ent-kaurene diterpene glucosides from Mikania micrantha

Author:
Li-Mei Dong; Xu-Chao Jia; Qing-Wen Luo; Yi-Ming Peng; Qiang Zhang; Bi Luo; Jian-Wen Tan
Source:
Phytochemistry letters 2017 v.20 pp. 155-159
ISSN:
1874-3900
Subject:
Gram-negative bacteria; Mikania micrantha; aerial parts; antibacterial properties; anticarcinogenic activity; chemical structure; diterpenoids; glucosides; humans; neoplasms; spectral analysis
Abstract:
... Phytochemical study on the aerial parts of Mikania micrantha led to the isolation of four new ent-kaurene diterpene glucosides, β-d-glucopyranosyl-15α-(3-hydroxy-3-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (1), β-d-glucopyranosyl-15α-(3-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (2), β-d-glucopyranosyl-15α-(2-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (3), β-d-glucopyra ...
DOI:
10.1016/j.phytol.2017.04.029

8. Four new iridoid glucosides containing the furan ring from the fruit of Cornus officinalis

Author:
Jun He; Xian-Sheng Ye; Xiao-Xue Wang; Ya-Nan Yang; Pei-Cheng Zhang; Bing-Zhi Ma; Wei-Ku Zhang; Jie-Kun Xu
Source:
Fitoterapia 2017 pp. -
ISSN:
0367-326X
Subject:
Cornus officinalis; chemical structure; circular dichroism spectroscopy; glucosides; iridoid glycosides; neuroprotective effect; nuclear magnetic resonance spectroscopy; spectral analysis; sugars
Abstract:
... Four new and rare iridoid glucosides, cornusfuroside A–D (1–4), containing the furan ring were identified from water extract of the fruit of Cornus officinalis. These new chemical structures were determined through extensive spectroscopic analysis, including 1D and 2D NMR, IR, HRESIMS, experimental and calculated electronic circular dichroism (ECD). Notably, this study is the first report on the i ...
DOI:
10.1016/j.fitote.2017.06.003

9. Furofuran lignan glucosides from the leaves of Vitex negundo var. cannabifolia

Author:
Yue-Ting Li; Man-Man Li; Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dao-Ran Pang; Jiao Zheng; Yun-Fang Zhao; Peng-Fei Tu; Jun Li
Source:
Natural product research 2017 v.31 no.8 pp. 918-924
ISSN:
1478-6427
Subject:
Vitex negundo; glucosides; inhibitory concentration 50; leaves; lignans; nitric oxide; spectral analysis; spectroscopy
Abstract:
... Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3 – 6), were isolated from the leaves of Vitex negundo var. cannabifolia . The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC ...
DOI:
10.1080/14786419.2016.1255887

10. Megastigmane glucosides isolated from Dichrocephala benthamii

Author:
Bo SONG; Jin-Guang SI; Meng YU; Xiao-Hui TIAN; Gang DING; Zhong-Mei ZOU
Source:
Chinese journal of natural medicines 2017 v.15 no.4 pp. 288-291
ISSN:
1875-5364
Subject:
Oriental traditional medicine; chemical composition; cytotoxicity; glucosides; hepatoma; humans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... The present study was designed to investigate the chemical constituents of the whole herb of Dichrocephala benthamii. A new megastigmane glucoside (compound 1), together with its four known analogues (compounds 2−5), was obtained. Their structures were elucidated on the basis of spectroscopic analyses (UV, IR, MS, and 1D and 2D NMR). The absolute configuration of compound 1 was assigned on the bas ...
DOI:
10.1016/S1875-5364(17)30046-8

11. Neolignan and megastigmane glucosides from the aerial parts of Isodon japonicus with cell protective effects on BaP-induced cytotoxicity

Author:
Takahiro Matsumoto; Seikou Nakamura; Souichi Nakashima; Tomoe Ohta; Keiko Ogawa; Masashi Fukaya; Junko Tsukioka; Tomohiro Hasei; Tetsushi Watanabe; Hisashi Matsuda
Source:
Phytochemistry 2017 v.137 pp. 101-108
ISSN:
0031-9422
Subject:
aerial parts; chemical structure; cytotoxicity; glucosides; lignans; nuclear magnetic resonance spectroscopy; protective effect; spectral analysis; Japan
Abstract:
... Six neolignan glucosides, named isodonosides I–VI, and a megastigmane glucoside named isodonmegastigmane I, were isolated together with 15 known compounds from the methanolic extract of aerial parts of Isodon japonicus cultivated in Tokushima, Japan. The chemical structures of the compounds were elucidated based on their MS and NMR spectroscopic analysis. The absolute configurations of the neolign ...
DOI:
10.1016/j.phytochem.2017.02.007

12. A New Biphenanthrene Glucoside with Cytotoxic Activity from Cremastra appendiculata

Author:
Xin-Qiao Liu; Wen-ke Yuan; Qiao-Yu Yuan; Xiao-Ping Li; Bin-hua Qin
Source:
Chemistry of natural compounds 2017 v.53 no.2 pp. 211-214
ISSN:
0009-3130
Subject:
chemistry; cytotoxicity; glucosides; spectral analysis; tubers
Abstract:
... A new biphenanthrene glucoside, named 2′,7-dihydroxy-4,4′-dimethoxy-1,1′-biphenanthrene-2,7′-di-O-β-D-glucoside, together with four known compounds were isolated from the tubers of Cremastra appendiculata (D. Don) Makino. Their structures were elucidated on the basis of spectral data. The cytotoxic activitiy of the new compound and four known compounds was tested. ...
DOI:
10.1007/s10600-017-1954-y

13. A New Insecticidal Lignan Glucoside from Galium verum

Author:
Jia Chen; Chun-Chao Zhao; Jian-Hua Shao; Ju-Di Fan; Xu-Hua Huang
Source:
Chemistry of natural compounds 2017 v.53 no.4 pp. 626-628
ISSN:
0009-3130
Subject:
Galium verum; Helicoverpa armigera; Scorpiones; chemical structure; glucosides; insecticidal properties; lignans; mortality; poisoning; scorpion venoms; spectral analysis; stomach; toxicity
Abstract:
... A new lignan glucoside, galiveroside A (1), and seven known compounds (2–8), were isolated from Galium verum L. The structure of 1 was elucidated on the basis of extensive spectroscopic analyses. Compound 1, at the concentration of 5 mg/mL, showed insecticide activity to 3 age cotton bollworm with a mortality of 16.3% through stomach poisoning. When combined with a recombinant scorpion toxin rLqh ...
DOI:
10.1007/s10600-017-2075-3

14. A New Lignan Glucoside from Cyclea racemosa

Author:
Jian-Hua Shao; Xue-Wei Zhang; Zi-Ling Dong; Si-Hui Li; Ben-Jie Miao; Ke-Zhi Cheng
Source:
Chemistry of natural compounds 2017 v.53 no.6 pp. 1025-1027
ISSN:
0009-3130
Subject:
Cyclea; chemical structure; glucosides; lignans; spectral analysis
Abstract:
... A new lignan glucoside 1, along with two known lignans (2, 3), was isolated from Cyclea racemosa Oliv. Its structure was elucidated as (+)-7′-methoxylariciresinol 4-O-β-D-glucopyranoside on the basis of extensive spectroscopic analyses. ...
DOI:
10.1007/s10600-017-2193-y

15. New aristolochic acid and other chemical constituents of Aristolochia maurorum growing wild in Jordan

Author:
Mohammed B. Al-Barham; Hala I. Al-Jaber; Mahmoud A. Al-Qudah; Musa H. Abu Zarga
Source:
Natural product research 2017 v.31 no.3 pp. 245-252
ISSN:
1478-6427
Subject:
Aristolochia; adenosine; alanine; beta-sitosterol; chemical composition; glucosides; nuclear magnetic resonance spectroscopy; palmitic acid; spectral analysis; uracil; Jordan
Abstract:
... Investigation of the chemical constituents of Aristolochia maurorum growing wild in Jordan resulted in the isolation and characterisation of one new compound in addition to 19 known compounds. The new compound was identified as aristolochic acid II alanine amide (14). The other known compounds were the following: palmitic acid (1), β-sitosterol (2), E -ethyl- p -coumarate (3), Z -ethyl- p -coumara ...
DOI:
10.1080/14786419.2016.1226833

16. Solanerioside A, an unusual 14,15-dinor-cyclophytane glucoside from the leaves of Solanum erianthum

Author:
Shi-yi Peng; Hang Li; De-po Yang; Bai Bai; Long-ping Zhu; Qin Liu; Juan Shen; Zhi-min Zhao
Source:
Natural product research 2017 v.31 no.7 pp. 810-816
ISSN:
1478-6427
Subject:
Solanum erianthum; antineoplastic activity; diterpenoids; glucosides; leaf extracts; leaves; methanol; nitric oxide; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Solanerioside A (1), the first example of a diterpenoid glucoside featuring a 14,15-dinor-cyclophytane scaffold, together with three known terpene glucosides (2 – 4) were isolated from the methanol extract of the leaves of Solanum erianthum (Solanaceae). The structure of 1 was mainly characterised on the basis of extensive spectroscopic analyses, especially from the 2D NMR spectra. In addition, th ...
DOI:
10.1080/14786419.2016.1247078

17. Three new monoterpene glucosides and one new sorbitol ester identified from Sibiraea angustata with hypolipidemic activities in HepG2 cells

Author:
Zheng-Zheng Yao; Hong-Dong Liu; Xiao-Tian Chen; Dong-Ming Zhang; Xue-Wen Lai; Peng Xu; Bin Li
Source:
Phytochemistry letters 2017 v.21 pp. 118-122
ISSN:
1874-3900
Subject:
caffeic acid; glucosides; human cell lines; monoterpenoids; sorbitol; spectral analysis
Abstract:
... Three new monoterpene glycosides, sibiraglycoside L (1), M (2), N (3) and one new sorbitol ester, resibirate (4), together with four known compounds including caffeic acid glucitol ester (5), sibiscolacton C (6), geraniol-1-O-[α-l-rhamnopyranosyl-(1→6)-1-β-d-glucopyranoside] (7), and sibiraglycoside K (8), respectively, were isolated from an aqueous extract of the aerial portion of Sibiraea angust ...
DOI:
10.1016/j.phytol.2017.06.015

18. Two new cytotoxic glycosides isolated from the green walnut husks of Juglans mandshurica Maxim.

Author:
Yuan-Yuan Zhou; Quan-Yu Liu; Bing-You Yang; Yan-Qiu Jiang; Yu-Xin Liu; Ying Wang; Shuang Guo; Haixue Kuang
Source:
Natural product research 2017 v.31 no.11 pp. 1237-1244
ISSN:
1478-6427
Subject:
Juglans; alcohols; cytotoxicity; glucosides; hulls; neoplasm cells; spectral analysis; walnuts
Abstract:
... Two new glycosides including an alcohol glycoside and a phenolic glycoside: hexyl-1- O - α - d -arabinofuranosyl-(1 → 6)- β - d -glucopyranoside (1), 4-hydroxypropiophenone-4- O - β - d -glucopyranosyl(1 → 6)- β - d -glucopyranoside(2), along with six known naphthalenyl glucosides (3 – 8) were isolated from green walnut husks of Juglans mandshurica , and their structures were elucidated on the bas ...
DOI:
10.1080/14786419.2016.1233412

19. Two new iridoid glycosides from Odontonema cuspidatum and their bioactivities

Author:
M.S. Refaey; Ahmed M.M. Hassanein; Mahmoud A.H. Mostafa; Amira S. Wanas; A.A. Ali
Source:
Phytochemistry letters 2017 v.22 pp. 27-32
ISSN:
1874-3900
Subject:
Acanthaceae; Escherichia coli; aerial parts; antimalarials; antimicrobial properties; cefotaxime; glucosides; inhibitory concentration 50; iridoid glycosides; nuclear magnetic resonance spectroscopy; spectral analysis; vancomycin; verbascoside
Abstract:
... Two new iridoid glycosides, named 6β-O-methyl-unedoside (1) and 6β-O-methyl-5-deoxythunbergioside (2) along with two known phenyl propanoid glucoside compounds dolichandroside A (3) and verbascoside (4) were isolated from the aerial parts of Odontonema cuspidatum (Nees) Kuntze (Acanthaceae). Structure elucidation of the new compounds was established by interpretation of their 1D and 2D-NMR spectra ...
DOI:
10.1016/j.phytol.2017.08.009

20. A furan-2-carbonyl C-glucoside and an alkyl glucoside from the parasitic plant, Dendrophthoe pentandra

Author:
Poolsak Sahakitpichan; Wannaporn Disadee; Rada Buntawong; Nitirat Chimnoi; Somsak Ruchirawat; Tripetch Kanchanapoom
Source:
Phytochemistry letters 2017 v.21 pp. 90-93
ISSN:
1874-3900
Subject:
Dendrophthoe; Mangifera indica; Tectona grandis; glucosides; parasitic plants; procyanidins; spectral analysis
Abstract:
... A new furan-2-carbonyl C-(6′-O-galloyl)-β-glucopyranoside (scleropentaside F, 1) and a new alkyl glucoside [butane-2,3-diol 2-(6′-O-galloyl)-O-β-glucopyranoside, 2] were isolated from the entire hemi-parasitic plant, Dendrophthoe pentandra growing on Tectona grandis together with ten known compounds including, benzyl-O-β-d-glucopyranoside (3), benzyl-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside ...
DOI:
10.1016/j.phytol.2017.05.024

21. A new oleanolic-type triterpene glycoside from Anchusa italica

Author:
Kui-Kui Chen; Zhou-Jian Xie; Wei Dai; Qi Wang
Source:
Natural product research 2017 v.31 no.8 pp. 959-965
ISSN:
1478-6427
Subject:
Anchusa azurea; alcohols; cytotoxicity; glucosides; humans; neoplasms; oleanolic acid; spectral analysis
Abstract:
... A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β- d -glucopyranosyl-(1→2)-β- d -glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1) , together with five analogues, oleanazuroside 1 (2) , oleanazuroside 2 (3) , 24-hydroxytormentic acid ester glucoside (4) , 24-epi-pinfaensin (5) , and oleanolic acid 3-O-α- l -arabinoside (6) were isolated from the n -butyl alcohol extract of Anchusa ...
DOI:
10.1080/14786419.2016.1258557

22. A new sulfonylated flavonoid and other bioactive compounds isolated from the aerial parts of Cotula anthemoides L.

Author:
Wafa Tadrent; Abdulmagid Alabdul Magid; Ahmed Kabouche; Dominique Harakat; Laurence Voutquenne-Nazabadioko; Zahia Kabouche
Source:
Natural product research 2017 v.31 no.12 pp. 1437-1445
ISSN:
1478-6427
Subject:
2,2-diphenyl-1-picrylhydrazyl; Cotula; aerial parts; bioactive compounds; flavonols; glucosides; inhibitory concentration 50; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... A new sulfonyl flavonol glucoside, 5,7,4′,5′-tetrahydoxyflavonol 2′-[propanoic acid-(2″′-acetoxy-1″′-sulfonyl)]-5′-O-β- d -glucopyranoside (1) was isolated from the aerial parts of Cotula anthemoides L. in addition to 15 known compounds (2 – 16). The structure elucidation of these compounds was based on analyses of spectroscopic data including 1D-, 2D-NMR and HR-ESI-MS techniques and by comparing ...
DOI:
10.1080/14786419.2016.1261342

23. Absolute configuration of resveratrol oligomer glucosides isolated from the leaves of Upuna borneensis

Author:
Tetsuro Ito; Hiromi Ito; Munekazu Iinuma
Source:
Phytochemistry letters 2017 v.20 pp. 26-31
ISSN:
1874-3900
Subject:
Dipterocarpaceae; chemical composition; glucosides; leaves; nuclear magnetic resonance spectroscopy; resveratrol; spectral analysis
Abstract:
... A comprehensive investigation of the chemical constituents of the leaves of Upuna borneensis (Dipterocarpaceae) was performed. Three new glucosides of resveratrol oligomers having a pentameric aglycone [upunoside E (1)] and dimeric aglycones [upunosides F (3) and G (4)], as well as 14 resveratrol derivatives (2, 5–17), were isolated. The absolute configurations of the new compounds were elucidated ...
DOI:
10.1016/j.phytol.2017.03.006

24. Anti-inflammatory and Antiosteoporosis Flavonoids from the Rhizomes of Helminthostachys zeylanica

Author:
Huang Yu-Ling; Shen Chien-Chang; Shen Yuh-Chiang; Chiou Wen-Fei; Chen Chien-Chih
Source:
Journal of natural products 2017 v.80 no.2 pp. 246-253
ISSN:
1520-6025
Subject:
Helminthostachys zeylanica; acid hydrolysis; anti-inflammatory activity; glucosides; inhibitory concentration 50; nitric oxide; osteoclasts; quercetin; rhizomes; spectral analysis; sugars
Abstract:
... Chemical investigation of the rhizomes of Helminthostachys zeylanica led to the isolation of eight new flavonoids including six cyclized geranylflavonoids, ugonins V–X (1–3), (10R,11S)-ugonin N (4), (10R,11S)-ugonin S (5), and ugonin Y (6), as well as two quercetin glucosides, quercetin-4′-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranoside (7) and quercetin-3-O-β-d-glucopyranosyl-4′-O-β-d-glucopyranos ...
DOI:
10.1021/acs.jnatprod.5b01164

25. Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides

Author:
Shahira M Ezzat; Maha M Salama; Engy A Mahrous; Louis Maes; Cheol-Ho Pan; Essam Abdel-Sattar
Source:
Natural product research 2017 v.31 no.6 pp. 676-680
ISSN:
1478-6427
Subject:
Leishmania infantum; Plasmodium falciparum; Trypanosoma brucei; Trypanosoma cruzi; Verbesina encelioides; cytotoxicity; glucosides; in vitro studies; metabolites; petroleum; spectral analysis
Abstract:
... The bioactive petroleum ether fraction of Verbesina encelioides , previously studied by the authors, was chosen for the isolation of antiprotozoal metabolites. Pseudotaraxasterol-3β-acetate (1), benzyl 2,6-dimethoxy benzoate (2), 16β-hydroxy-pseudotaraxasterol-3β-palmitate (3) and pseudotaraxasterol (4), in addition to β -sitosterol glucoside (5) and β -sitosterol galactoside (6) were isolated and ...
DOI:
10.1080/14786419.2016.1180604

26. Bioactive steroids and sorbicillinoids isolated from the endophytic fungus Trichoderma sp. Xy24

Author:
Jin-Lian Zhao; Min Zhang; Ji-Mei Liu; Zhen Tan; Ri-Dao Chen; Ke-Bo Xie; Jun-Gui Dai
Source:
Journal of Asian natural products research 2017 v.19 no.10 pp. 1028-1035
ISSN:
1477-2213
Subject:
Human immunodeficiency virus 1; Trichoderma; cytotoxicity; endophytes; fungi; glucosides; human cell lines; inhibitory concentration 50; neuroglia; nitric oxide; spectral analysis; steroids; viruses
Abstract:
... A new steroid glucoside (1), along with nine known steroids (2–10) and four known sorbicillinoids (11–14), were isolated from the endophytic fungus Trichoderma sp. Xy24. Their structures were elucidated on the basis of spectroscopic data analyses and by comparison with reported data. Compounds 3 , 5–7 , 9 , 10 , and 13 exhibited significant inhibitory effects on HIV-1 virus with IC ₅₀ values rangi ...
DOI:
10.1080/10286020.2017.1285908

27. Clerodane Diterpenoid Glucosides from the Stems of Tinospora sinensis

Author:
Jiang Huan; Zhang Gui-Jie; Liu Yan-Fei; Wang Heng-Shan; Liang Dong
Source:
Journal of natural products 2017 v.80 no.4 pp. 975-982
ISSN:
1520-6025
Subject:
Tinospora sinensis; cytotoxicity; diterpenoids; ethyl acetate; glucosides; inhibitory concentration 50; nitric oxide; spectral analysis; stems
Abstract:
... Ten new clerodane diterpenoid glucosides (1–10) and three known analogues (11–13) were isolated from an EtOAc extract of the stems of Tinospora sinensis. Spectroscopic analyses and chemical methods were used to elucidate the structures of these isolates. The absolute configurations of tinosinenosides A–C (1–3) were established by using experimental and calculated ECD data. Their cytotoxicity again ...
DOI:
10.1021/acs.jnatprod.6b00976

28. Cytotoxic Cardiac Glycoside from the Parasitic Plant Cuscuta reflexa

Author:
Muhammad Ali Versiani; Asma Kanwal; Shaheen Faizi; Ahsana Dar Farooq
Source:
Chemistry of natural compounds 2017 v.53 no.5 pp. 915-922
ISSN:
0009-3130
Subject:
Cuscuta reflexa; anticarcinogenic activity; beta-sitosterol; bioassays; chemical structure; coumarins; cytotoxicity; fractionation; glucosides; nuclear magnetic resonance spectroscopy; parasitic plants; prostatic neoplasms; spectral analysis; stable isotopes; ursolic acid
Abstract:
... Bioassay guided fractionation of the cytotoxic extract of the plant Cuscuta reflexa, employing cytotoxic assay against a panel of 60 cell lines, led to the isolation of 13 compounds identified as odoroside H (1), 21-hydroxyodoroside H (2), neritaloside (3), strospeside (4), 16-β-hydroxydigitoxin (5), N-trans and cis feruloyl tyramines (6 and 7), ethyl caffeate (8), coumarins (9 and 10), ursolic ac ...
DOI:
10.1007/s10600-017-2154-5

29. Enzymatic biosynthesis of novel neobavaisoflavone glucosides via Bacillus UDP-glycosyltransferase

Author:
Tao MA; Yi-Qun DAI; Nan LI; Qiang HUO; Hong-Mei LI; Yu-Xin ZHANG; Zheng-Hao PIAO; Cheng-Zhu WU
Source:
Chinese journal of natural medicines 2017 v.15 no.4 pp. 281-287
ISSN:
1875-5364
Subject:
Oriental traditional medicine; biosynthesis; cytotoxicity; glucosides; glycosylation; high performance liquid chromatography; human cell lines; humans; inhibitory concentration 50; mass spectrometry; neoplasms; nuclear magnetic resonance spectroscopy; spectral analysis; transferases; water solubility
Abstract:
... The present study was designed to perform structural modifications of of neobavaisoflavone (NBIF), using an in vitro enzymatic glycosylation reaction, in order to improve its water-solubility. Two novel glucosides of NBIF were obtained from an enzymatic glycosylation by UDP-glycosyltransferase. The glycosylated products were elucidated by LC-MS, HR-ESI-MS, and NMR analysis. The HPLC peaks were int ...
DOI:
10.1016/S1875-5364(17)30045-6

30. Flavanonol glucosides from the aerial parts of Agrimonia pilosa Ledeb. and their acetylcholinesterase inhibitory effects

Author:
U. Min Seo; Duc Hung Nguyen; Bing Tian Zhao; Byung Sun Min; Mi Hee Woo
Source:
Carbohydrate research 2017 pp. -
ISSN:
0008-6215
Subject:
Agrimonia; acetylcholinesterase; aerial parts; glucosides; inhibitory concentration 50; isomers; spectral analysis
Abstract:
... Two new flavanonol glucoside isomers, (2R,3S)-dihydrokaempferol 3-O-β-D-glucoside (1) and (2S,3R)-dihydrokaempferol 3-O-β-D-glucoside (2), were isolated from the aerial parts of Agrimonia pilosa Ledeb., along with eight known flavanonol glucosides (3–10). Their structures were determined on the basis of spectroscopic analysis. In addition, these compounds were evaluated to determine their acetylch ...
DOI:
10.1016/j.carres.2017.04.014

31. Four new glycosides from the stems of Dendrobium fimbriatum Hook

Author:
Feng-Qing Xu; Wei-Wei Fan; Cheng-Ting Zi; Fa-Wu Dong; Dan Yang; Jun Zhou; Jiang-Miao Hu
Source:
Natural product research 2017 v.31 no.7 pp. 797-801
ISSN:
1478-6427
Subject:
Dendrobium; glucosides; spectral analysis; spectroscopy; stems
Abstract:
... Four new glucosides, named as gigantol-5- O - β - d -glucopyranoside (1), 9,10-dihydro-aphyllone A-5- O - β - d -glucopyranoside (2), ficusal-4- O - β - d -glucopyranoside (3), botrydiol-15- O - β - d -glucopyranoside (4), together with eight known compounds (5–12) were isolated from the n -BuOH extract of the stems of Dendrobium fimbriatum Hook. Their structures were elucidated by the analyses of ...
DOI:
10.1080/14786419.2016.1247076

32. Hepatoprotective hemiterpene glycosides from the rhizome of Cibotium barometz (L.) J. Sm

Author:
Mei-Ping Xie; Lan Li; Hua Sun; An-Qi Lu; Bo Zhang; Jian-Gong Shi; Dan Zhang; Su-Juan Wang
Source:
Phytochemistry 2017 v.138 pp. 128-133
ISSN:
0031-9422
Subject:
Cibotium barometz; cytotoxicity; glucosides; hepatoprotective effect; liver; neuroprotective effect; nuclear magnetic resonance spectroscopy; rhizomes; spectral analysis
Abstract:
... Five previously undescribed hemiterpene glycosides, cibotiumbarosides E−I, and two known hemiterpene glucosides, were isolated from the rhizome of Cibotium barometz (L.) J. Sm. The structures of cibotiumbarosides E−I were established by 1D and 2D NMR spectroscopic analyses and HRMS. The absolute configuration of the aglycone of cibotiumbaroside E was assigned by calculated ECD with the TDDFT metho ...
DOI:
10.1016/j.phytochem.2017.02.023

33. Nine new compounds from the root bark of Lycium chinense and their α-glucosidase inhibitory activity

Author:
Ya-Nan Yang; Ya-Wen An; Zhi-Lai Zhan; Jing Xie; Jian-Shuang Jiang; Zi-Ming Feng; Fei Ye; Pei-Cheng Zhang
Source:
RSC advances 2017 v.7 no.2 pp. 805-812
ISSN:
2046-2069
Subject:
Lycium chinense; acarbose; alpha-glucosidase; bark; cortex; enzyme inhibition; enzyme inhibitors; fruits; glucosides; inhibitory concentration 50; lignans; naphthalene; nuclear magnetic resonance spectroscopy; sesquiterpenoids; shrubs; spectral analysis
Abstract:
... Lycium chinense Mill. is a deciduous shrub in the Solanaceae family that is known for its fruits (Lycii fructus) and root bark (Lycii cortex). In our ongoing search for α-glucosidase inhibitors from the root bark of L. chinense, lyciumflavane A, one new flavane with an unusual benzofuran unit, one new amide possessing a naphthalene skeleton, one new sesquiterpene, three new lignan glucosides, and ...
DOI:
10.1039/c6ra24751b

34. Phenolic glycosides and monoterpenoids from the roots of Euphorbia ebracteolata and their bioactivities

Author:
An-Hua Wang; Xiao-Kui Huo; Lei Feng; Cheng-Peng Sun; Sa Deng; Hou-Li Zhang; Bao-Jing Zhang; Xiao-Chi Ma; Jing-Ming Jia; Chao Wang
Source:
Fitoterapia 2017 v.121 pp. 175-182
ISSN:
0367-326X
Subject:
2,2-diphenyl-1-picrylhydrazyl; Euphorbia; anticarcinogenic activity; antioxidant activity; ascorbic acid; bioassays; chemical structure; chromatography; cytotoxicity; electrospray ionization mass spectrometry; fluorescence; glucosides; humans; inhibitory concentration 50; medicinal plants; monoterpenoids; neoplasms; nuclear magnetic resonance spectroscopy; phenolic acids; roots; spectral analysis
Abstract:
... The bioactive substance investigation of Euphorbia ebracteolata obtained 17 compounds by various chromatographic techniques. Their structures were elucidated using widely spectroscopic data, including ESI-MS, HRESI-MS, CD, 1D- and 2D-NMR, which gave 5 new phenolic glucosides and 4 new monoterpenoids. The phenolic glucosides and monoterpenoids showed the inhibitory effect against the human carboxyl ...
DOI:
10.1016/j.fitote.2017.06.026

35. Phenylphenalenone glycosides: Occurrence, structure revision, and substituent effects on the steric orientation

Author:
Bernd Schneider
Source:
Phytochemistry letters 2017 v.21 pp. 104-108
ISSN:
1874-3900
Subject:
Haemodoraceae; Musaceae; chemotaxonomy; glucosides; naphthalic anhydride; nuclear magnetic resonance spectroscopy; spectral analysis; sugars
Abstract:
... Glycosides and acyl glycosides of phenylphenalenones, phenylbenzoisochromenones, and structurally related natural products from plants are compiled. With the exception of one naphthalic anhydride glucoside from the Musaceae, all glycosides are chemotaxonomic markers of the Haemodoraceae, subfamily Haemodoroideae. NMR spectroscopic data indicate that in 6-O-glycosides of phenylphenalenones and phen ...
DOI:
10.1016/j.phytol.2017.06.004

36. Rigenolides B and C, conjugates of norsecoiridoid and secoiridoid glucoside from Gentiana rigescens Franch

Author:
Yoshihiro Suyama; Naonobu Tanaka; Kazuyoshi Kawazoe; Kotaro Murakami; Shun-Lin Li; Han-Dong Sun; Yoshiki Kashiwada
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
Gentiana rigescens; chemical reactions; chemical structure; glucosides; herbal medicines; organic compounds; spectral analysis
Abstract:
... Two new conjugates of norsecoiridoid and secoiridoid glucoside, rigenolides B (1) and C (2), were isolated from a Chinese herbal medicine Gentiana rigescens Franch. Their structures were established by comprehensive spectroscopic analysis. The absolute configurations of 1 and 2 were elucidated by comparison of the ECD spectra with TDDFT calculated spectra. ...
DOI:
10.1016/j.tetlet.2017.02.075

37. Specialized metabolites from the aerial parts of Centaurea polyclada DC.

Author:
Serdar Demir; Canan Karaalp; Erdal Bedir
Source:
Phytochemistry 2017 v.143 pp. 12-18
ISSN:
0031-9422
Subject:
Centaurea; aerial parts; chemical degradation; flavonoids; flora; glucosides; lignans; mass spectrometry; metabolites; nuclear magnetic resonance spectroscopy; sesquiterpenoid lactones; spectral analysis; Turkey (country)
Abstract:
... The genus Centaurea L. (Asteraceae) is represented by 200 taxa in the flora of Turkey and several Centaurea species are used as herbal remedies against different conditions. Previous phytochemical investigations on this genus generally revealed the isolation of sesquiterpene lactones and flavonoid derivatives. In our continuous search on Centaurea genus, a phytochemical study was performed on Cent ...
DOI:
10.1016/j.phytochem.2017.07.002

38. Termiglaucescin, a new polyhydroxy triterpene glucoside from Terminalia glaucescens with antioxidant and anti-inflammatory potential

Author:
Amadou Dawé; Benjamin Talom; Gilbert Deccaux Wabo Fotso Kapche; Kauser Siddiqui; Fawai Yakai; Emmanuel Talla; Muhammad Ali Shaiq; Iqbal Lubna; Bonabenture Tchaleu Ngadjui
Source:
Zeitschrift für Naturforschung 2017 v.72 no.5-6 pp. 203-208
ISSN:
1865-7125
Subject:
Terminalia; anti-inflammatory activity; antioxidants; bark; beta-sitosterol; ethyl acetate; glucosides; nuclear magnetic resonance spectroscopy; spectral analysis; stigmasterol; triterpenoids
Abstract:
... Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark of Terminalia glaucescens Planch. ex Benth, together with 11 known compounds, β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (2), arjunglucoside I (3), sericoside (4), arjungenin (5), sericic acid (6), arjunetin (7), chebuloside II (8), 3,3′,4-tri-O-methylelagic ...
DOI:
10.1515/znc-2016-0178

39. Two new compounds from the green peel of Juglans mandshurica

Author:
Jing Li; Kang-Ping Xu; Zhen-Xing Zou; Hui Zou; Hong-Ping Long; Lei-Hong Tan; Rui-Huan Liu; Yi-Kun Wang; Ping-Sheng Xu; Gui-Shan Tan
Source:
Journal of Asian natural products research 2017 v.19 no.11 pp. 1087-1092
ISSN:
1477-2213
Subject:
Juglans mandshurica; cell lines; cytotoxicity; flavones; glucosides; neoplasm cells; neoplasms; spectral analysis
Abstract:
... A new cyclic diarylheptanoid (1) and a new flavone glucoside (2), along with seven known compounds, were isolated from the green peel of Juglans mandshurica. Their structures were elucidated based on extensive spectroscopic analyses. Moreover, the cytotoxicity against NCI-H460, A549, and K562 cancer cells of compounds 1–6 was evaluated. The results showed that compound 3 exhibited moderate inhibit ...
DOI:
10.1080/10286020.2017.1295228

40. Two new lignan-iridoid glucoside diesters from the leaves of Vaccinium bracteatum and their relative and absolute configuration determination by DFT NMR and TDDFT-ECD calculation

Author:
Yong-Mei Ren; Chang-Qiang Ke; Attila Mándi; Tibor Kurtán; Chunping Tang; Sheng Yao; Yang Ye
Source:
Tetrahedron 2017 pp. -
ISSN:
0040-4020
Subject:
Vaccinium bracteatum; biochemical pathways; chemical reactions; chemical structure; circular dichroism spectroscopy; glucosides; iridoids; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Two new lignan-iridoid glucoside diesters (2 and 3), together with their putative biosynthetic precursor 10-O-trans-caffeoyl-6α-hydroxyl-dihydromonotropein (1), were characterized from the leaves of Vaccinium bracteatum. Their planar structures and relative configuration were elucidated by spectroscopic measurements and DFT C NMR calculations, and their absolute configurations were determined by t ...
DOI:
10.1016/j.tet.2017.04.040

41. A new iridoid glycoside from the fruits of Vitex rotundifolia

Author:
Yuan-Yu Zhao; Lian Guo; Lan-Jie Cao; Jian Zhang; Zhi-Qi Yin
Source:
Natural product research 2017 v.31 no.21 pp. 2491-2496
ISSN:
1478-6427
Subject:
Vitex rotundifolia; aucubin; cytotoxicity; diterpenoids; flavonoids; fruits; glucosides; inhibitory concentration 50; spectral analysis; triterpenoids
Abstract:
... One new iridoid glycoside, 6′,10-di- O -(4-hydroxybenzoyl) aucubin (1), together with ten known compounds, including five diterpenoids (2-6), two triterpene glucosides (7-8) and three methoxylated flavonoids (9-11) were isolated from the fruits of Vitex rotundifolia . Compounds (3 , 4 , 7, and 8) were reported for the first time from this plant. Their structures were elucidated by spectral analysi ...
DOI:
10.1080/14786419.2017.1314284