U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication Year 2017 Remove constraint Publication Year: 2017 Subject glucosides Remove constraint Subject: glucosides
Start Over

Search

221  Search Results

« Previous | 1 - 100 of 221 |
Number of results to display per page

Search Results

1. 2-Carboxy-dihydrostilbene and flavan glycosides from Desmodium heterocarpon

Author:
Poolsak Sahakitpichan; Piyawadee Chadmuk; Nitirat Chimnoi; Anucha Namsa-aid; Somsak Ruchirawat; Tripetch Kanchanapoom
Source:
Phytochemistry letters 2017 v.19 pp. 94-97
ISSN:
1874-3900
Subject:
Desmodium heterocarpon; flavonoids; glucosides; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... A new 2-carboxy-dihydrostilbene glucoside, 2-carboxy-3,5,4′-trihydroxydihydrostilbene 3-O-β-d-glucopyranoside (1) and a new flavan diglycoside, (2S)-5,7,4′-trihydroxyflavan 7-O-β-d-apiofuranosyl-(1→6)-O-β-d-glucopyranoside (3) were isolated from the aerial portion of Thai origin Desmodium heterocarpon together with five known compounds, lunularic acid 4′-O-β-d-glucopyranoside (2), vitexin (4), iso ...
DOI:
10.1016/j.phytol.2016.12.011

2. Abietane diterpenoids from Sideritis montana L. and their antiproliferative activity

Author:
Barbara Tóth; Norbert Kúsz; Peter Forgo; Noémi Bózsity; István Zupkó; Gyula Pinke; Judit Hohmann; Andrea Vasas
Source:
Fitoterapia 2017 pp. -
ISSN:
0367-326X
Subject:
Sideritis; anticarcinogenic activity; diterpenoids; glucosides; humans; medicinal plants; methanol; neoplasms; nuclear magnetic resonance spectroscopy
Abstract:
... The present study aimed at the phytochemical and pharmacological investigation of Sideritis montana L. (Lamiaceae). Two new abietane diterpenes [sideritins A (1) and B (2)] were isolated from the methanol extract of the plant. Six known compounds [pomiferin E (3), 9α,13α-epi-dioxyabiet-8(14)-en-18-ol (4), paulownin (5), 6-methoxysakuranetin (6), 3-oxo-α-ionol (7) and 4-allyl-2,6-dimethoxyphenol gl ...
DOI:
10.1016/j.fitote.2017.08.016

3. Absolute configuration of resveratrol oligomer glucosides isolated from the leaves of Upuna borneensis

Author:
Tetsuro Ito; Hiromi Ito; Munekazu Iinuma
Source:
Phytochemistry letters 2017 v.20 pp. 26-31
ISSN:
1874-3900
Subject:
Dipterocarpaceae; chemical composition; glucosides; leaves; nuclear magnetic resonance spectroscopy; resveratrol; spectral analysis
Abstract:
... A comprehensive investigation of the chemical constituents of the leaves of Upuna borneensis (Dipterocarpaceae) was performed. Three new glucosides of resveratrol oligomers having a pentameric aglycone [upunoside E (1)] and dimeric aglycones [upunosides F (3) and G (4)], as well as 14 resveratrol derivatives (2, 5–17), were isolated. The absolute configurations of the new compounds were elucidated ...
DOI:
10.1016/j.phytol.2017.03.006

4. Adaptation in Caco-2 Human Intestinal Cell Differentiation and Phenolic Transport with Chronic Exposure to Blackberry (Rubus sp.) Extract

Author:
Redan Benjamin W.; Albaugh George P.; Charron Craig S.; Novotny Janet A.; Ferruzzi Mario G.
Source:
Journal of agricultural and food chemistry 2017 v.65 no.13 pp. 2694-2701
ISSN:
1520-5118
Subject:
ABC transporters; Rubus; absorption; anthocyanins; bioavailability; blackberries; cell differentiation; chronic exposure; dietary exposure; enzymes; epicatechin; gene expression; glucosides; human cell lines; humans; intestines; kaempferol; messenger RNA; metabolism; phenolic acids; uridine diphosphate
Abstract:
... As evidence mounts for a health-protective role of dietary phenolics, the importance of understanding factors influencing bioavailability increases. Recent evidence has suggested chronic exposure to phenolics may impact their absorption and metabolism. To explore alterations occurring from chronic dietary exposure to phenolics, Caco-2 cell monolayers were differentiated on Transwell inserts with 0 ...
DOI:
10.1021/acs.jafc.7b00027

5. Alterations of the Benzoxazinoid Profiles of Uninjured Maize Seedlings During Freezing, Storage, and Lyophilization

Author:
Pedersen Hans Albert; Heinrichson Kirsten; Fomsgaard Inge S.
Source:
Journal of agricultural and food chemistry 2017 v.65 no.20 pp. 4103-4110
ISSN:
1520-5118
Subject:
aqueous solutions; benzoxazinoids; bioactive properties; corn; enzymatic hydrolysis; enzymes; freeze drying; freezing; glucosides; high performance liquid chromatography; hydrolysis; hydroxamic acids; lactams; mass spectrometry; seedlings
Abstract:
... Benzoxazinoids are highly studied compounds due to their biological activity and presence in several cereals. They include compound classes such as hydroxamic acids and lactams and usually occur as inactive glucosides in unstressed plants. Injury to the plant causes enzymatic hydrolysis of the inactive glucosides to the biologically active hydroxamic acid and lactam aglucones. The hydroxamic acids ...
DOI:
10.1021/acs.jafc.7b01158

6. Analysis of Phenolic Compounds in Rooibos Tea (Aspalathus linearis) with a Comparison of Flavonoid-Based Compounds in Natural Populations of Plants from Different Regions

Author:
Stander Maria A.; Van Wyk Ben-Erik; Taylor Malcolm J. C.; Long Helen S.
Source:
Journal of agricultural and food chemistry 2017 v.65 no.47 pp. 10270-10281
ISSN:
1520-5118
Subject:
Aspalathus linearis; chemical composition; ecotypes; glucosides; mass spectrometry; phenolic compounds; phloridzin; tea
Abstract:
... Tea samples from 17 populations of “wild tea” ecotypes Aspalathus linearis (rooibos tea) and 2 populations of Aspalathus pendula were analyzed. Recent advances in column technology together with high-resolution mass spectrometry were applied to improve resolution, facilitating the identification of several new compounds as well as grouping of the wild tea ecotypes according to their chemical compo ...
DOI:
10.1021/acs.jafc.7b03942

7. Anti-inflammatory and Antiosteoporosis Flavonoids from the Rhizomes of Helminthostachys zeylanica

Author:
Huang Yu-Ling; Shen Chien-Chang; Shen Yuh-Chiang; Chiou Wen-Fei; Chen Chien-Chih
Source:
Journal of natural products 2017 v.80 no.2 pp. 246-253
ISSN:
1520-6025
Subject:
Helminthostachys zeylanica; acid hydrolysis; anti-inflammatory activity; glucosides; inhibitory concentration 50; nitric oxide; osteoclasts; quercetin; rhizomes; spectral analysis; sugars
Abstract:
... Chemical investigation of the rhizomes of Helminthostachys zeylanica led to the isolation of eight new flavonoids including six cyclized geranylflavonoids, ugonins V–X (1–3), (10R,11S)-ugonin N (4), (10R,11S)-ugonin S (5), and ugonin Y (6), as well as two quercetin glucosides, quercetin-4′-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranoside (7) and quercetin-3-O-β-d-glucopyranosyl-4′-O-β-d-glucopyranos ...
DOI:
10.1021/acs.jnatprod.5b01164

8. Anti-obesity and antioxidant activities of selected medicinal plants and phytochemical profiling of bioactive compounds

Author:
Hafeedza Abdul Rahman; Nazamid Saari; Faridah Abas; Amin Ismail; Muhammad Waseem Mumtaz; Azizah Abdul Hamid
Source:
International journal of food properties 2017 v.20 no.11 pp. 2616-2629
ISSN:
1094-2912
Subject:
2,2-diphenyl-1-picrylhydrazyl; Andrographis paniculata; Carica papaya; Cosmos caudatus; Lawsonia inermis; Melicope; Pereskia; Piper betle; Pluchea; antioxidant activity; bioactive compounds; catechin; functional foods; glucose; glucosides; herbs; inhibitory concentration 50; medicinal plants; metabolites; obesity; procyanidins; quercetin; quinic acid; screening; solvents; triacylglycerol lipase
Abstract:
... The present study describes the screening of eight herbs namely Cosmos caudatus, Pluchea indica, Lawsonia inermis, Carica papaya, Piper betle, Andrographis paniculata, Pereskia bleo , and Melicope lunu based on their anti-obesity and antioxidant activities. Out of all tested herbs, Cosmos caudatus demonstrated excellent anti-obesity and antioxidant potential with pancreatic lipase inhibitory effec ...
DOI:
10.1080/10942912.2016.1247098

9. Antibacterial screening of Rumex species native to the Carpathian Basin and bioactivity-guided isolation of compounds from Rumex aquaticus

Author:
Orsolya Orbán-Gyapai; Erika Liktor-Busa; Norbert Kúsz; Dóra Stefkó; Edit Urbán; Judit Hohmann; Andrea Vasas
Source:
Fitoterapia 2017 pp. -
ISSN:
0367-326X
Subject:
Bacillus subtilis; Escherichia coli; Klebsiella pneumoniae; Moraxella catarrhalis; Pseudomonas aeruginosa; Rumex aquaticus; Staphylococcus epidermidis; Streptococcus pyogenes; aerial parts; antibacterial properties; basins; catechin; chloroform; emodin; glucosides; hexane; indigenous species; methanol; methicillin-resistant Staphylococcus aureus; microorganisms; naphthalenes; quercetin; resveratrol; roots; screening; traditional medicine
Abstract:
... Plants belonging to the genus Rumex (family Polygonaceae) are used worldwide in traditional medicine for the treatment of various diseases caused by different microorganisms (e.g. bacteria-related dermatologic conditions, dysentery and enteritis). The present study focused on the antibacterial screening of Rumex species native to the Carpathian Basin, and isolation of compounds from one of the mos ...
DOI:
10.1016/j.fitote.2017.03.009

10. Antimicrobial and antioxidant activities of a new metabolite from Quercus incana

Author:
Farah Gul; Khalid Mohammed Khan; Achyut Adhikari; Salman Zafar; Muhammad Akram; Haroon Khan; Muhammad Saeed
Source:
Natural product research 2017 v.31 no.16 pp. 1901-1909
ISSN:
1478-6427
Subject:
Candida glabrata; Quercus leucotrichophora; Streptococcus pyogenes; antibacterial properties; antifungal properties; antioxidant activity; bark; beta-sitosterol; betulinic acid; butylated hydroxyanisole; catechin; ethyl acetate; fungi; gallic acid; glucosides; metabolites; quercetin
Abstract:
... Phytochemical investigations of Quercus incana led to the isolation of a new catechin derivative quercuschin (1), along with six known compounds: quercetin (2), methyl gallate (3), gallic acid (4), betulinic acid (5), (Z)-9-octadecenoic acid methyl ester (6) and β-sitosterol glucoside (7) from the ethyl acetate fraction of methanolic extract of the bark. Compound 1 was screened for its antibacteri ...
DOI:
10.1080/14786419.2016.1266347

11. Antioxidant Activity and α‐Amylase Inhibitory Effect of Polyphenolic‐Rich Extract from Origanum Glandulosum Desf

Author:
Afef Béjaoui; Abdennacer Boulila; Adnen Sanaa; Mohamed Boussaid; Xavier Fernandez
Source:
Journal of food biochemistry 2017 v.41 no.1 pp. -
ISSN:
0145-8884
Subject:
Origanum vulgare subsp. glandulosum; acarbose; alpha-amylase; animals; antioxidant activity; antioxidants; bronchitis; caffeic acid; carvacrol; clinical trials; fever; food additives; functional foods; glucosides; indigenous species; inhibitory concentration 50; mass spectrometry; noninsulin-dependent diabetes mellitus; phytopharmaceuticals; traditional medicine; whooping cough
Abstract:
... The polyphenolic‐rich extract of Tunisian Origanum glandulosum Desf. was investigated for its phenolic composition, antioxidant activity and potential to contribute to the dietary management of type II diabetes. By mean of an ultra‐performance liquid chromatography‐electrospray ionization‐ mass spectrometry (UPLC‐PDA‐ESI‐MS) 16 phenolics were characterized. The major detected compounds are caffeic ...
DOI:
10.1111/jfbc.12271

12. Antioxidant activity of broad bean seed extract and its phenolic composition

Author:
Ryszard Amarowicz; Fereidoon Shahidi
Source:
Journal of functional foods 2017 v.38 pp. 656-662
ISSN:
1756-4646
Subject:
2,2-diphenyl-1-picrylhydrazyl; acetone; antioxidant activity; antioxidants; catechin; chromatography; emulsions; epicatechin; ethanol; faba beans; glucosides; phenolic acids; procyanidins; seed extracts; seeds
Abstract:
... The crude acetonic extract of broad bean seeds was separated into fraction I (low-molecular-weight compounds) and fraction II (tannin fraction) using Sephadex LH-20 column chromatography with ethanol and acetone/water (1:1, v/v) as the mobile phases. Phenolics present in the crude extract and fractions thereof showed antioxidant and radical-scavenging properties determined using several methods (e ...
DOI:
10.1016/j.jff.2017.04.002

13. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense

Author:
Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
Source:
Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
ISSN:
1477-2213
Subject:
2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
DOI:
10.1080/10286020.2016.1234456

14. Antioxidant defense during desiccation of the resurrection plant Haberlea rhodopensis

Author:
Katya Georgieva; Soleya Dagnon; Emiliya Gesheva; Dimitar Bojilov; Gergana Mihailova; Snezhana Doncheva
Source:
Plant physiology and biochemistry 2017 v.114 pp. 51-59
ISSN:
0981-9428
Subject:
antioxidant activity; antioxidants; drought tolerance; drying; flavonoids; glucosides; oxidative stress; polyphenols
Abstract:
... Maintaining a strong antioxidant system is essential for preventing drought-induced oxidative stress. Thus, in the present study we investigated the role of some non-enzymic and enzymic antioxidants in desiccation tolerance of Haberlea rhodopensis. The effects of high light upon desiccation on antioxidant capacity was estimated by comparing the response of shade and sun plants. The significant enh ...
DOI:
10.1016/j.plaphy.2017.02.021

15. Antiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents

Author:
Olivia Jansen; Alembert T. Tchinda; Jean Loua; Virginie Esters; Ewa Cieckiewicz; Allison Ledoux; Paul D. Toukam; Luc Angenot; Monique Tits; Aliou M. Balde; Michel Frédérich
Source:
Journal of ethnopharmacology 2017 v.203 pp. 20-26
ISSN:
0378-8741
Subject:
Plasmodium falciparum; active ingredients; antimalarials; antiparasitic properties; beta-sitosterol; concrete; diterpenoids; ethanol; evaporation; fractionation; gallic acid; gel chromatography; glucosides; herbal medicines; human cell lines; inhibitory concentration 50; kaempferol; lactate dehydrogenase; leaf extracts; leaves; malaria; parasites; quercetin; resveratrol; spectroscopy; traditional medicine; Guinea
Abstract:
... Decoctions of the leaves of M. benthamianum Baill. are used by traditional healers in Guinea to treat malaria and this use was validated by a preliminary clinical assay.To evaluate the in vitro antiplasmodial activity and to identify active compounds from extracts of M. benthamianum leaves.Antiplasmodial activity of extracts, fractions and pure compounds was evaluated in vitro against a chloroquin ...
DOI:
10.1016/j.jep.2017.03.021

16. Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides

Author:
Shahira M Ezzat; Maha M Salama; Engy A Mahrous; Louis Maes; Cheol-Ho Pan; Essam Abdel-Sattar
Source:
Natural product research 2017 v.31 no.6 pp. 676-680
ISSN:
1478-6427
Subject:
Leishmania infantum; Plasmodium falciparum; Trypanosoma brucei; Trypanosoma cruzi; Verbesina encelioides; cytotoxicity; glucosides; in vitro studies; metabolites; petroleum; spectral analysis
Abstract:
... The bioactive petroleum ether fraction of Verbesina encelioides , previously studied by the authors, was chosen for the isolation of antiprotozoal metabolites. Pseudotaraxasterol-3β-acetate (1), benzyl 2,6-dimethoxy benzoate (2), 16β-hydroxy-pseudotaraxasterol-3β-palmitate (3) and pseudotaraxasterol (4), in addition to β -sitosterol glucoside (5) and β -sitosterol galactoside (6) were isolated and ...
DOI:
10.1080/14786419.2016.1180604

17. Apocynin derivatives from Iris tectorum

Author:
Chun-Lei Zhang; Guo-Ru Shi; Yan-Fei Liu; Yan Wang; Ruo-Yun Chen; De-Quan Yu
Source:
Journal of Asian natural products research 2017 v.19 no.2 pp. 128-133
ISSN:
1477-2213
Subject:
Iris (Iridaceae); chemical derivatives; chemical structure; glucosides; rhizomes; spectral analysis
Abstract:
... Phytochemical investigation of the rhizomes of Iris tectorum resulted in the isolation and characterization of three new apocynin derivatives, apocynin-4-O- β -D-(6′-O-syringyl)glucopyranoside (1), scrophenoside C-7-ethyl ether (2 , 3), together with a new naturally occurring compound but known by synthesis, apocynin-4-O- β -D-xylopyranoside (4), and five known ones (5–9). Their structures were el ...
DOI:
10.1080/10286020.2016.1268128

18. Aroma Glycosides in Grapes and Wine

Author:
Jibin Liu; Xiao‐Lin Zhu; Niamat Ullah; Yong‐Sheng Tao
Source:
Journal of food science 2017 v.82 no.2 pp. 248-259
ISSN:
0022-1147
Subject:
analytical methods; chemical structure; glucosides; grapes; hydrolysis; odors; volatile compounds; wines
Abstract:
... The major aroma components in grapes and wine include free volatile compounds and glycosidic nonvolatile compounds. The latter group of compounds is more than 10 times abundant of the former, and constitutes a big aroma reserve in grapes and wine. This review summarizes the research results obtained recently for the identification of aroma glycosides in grapes and wine, including grape glycoside s ...
DOI:
10.1111/1750-3841.13598

19. Authentication of Indian citrus fruit/fruit juices by untargeted and targeted metabolomics

Author:
Z. Jandrić; M. Islam; D.K. Singh; A. Cannavan
Source:
Food control 2017 v.72 pp. 181-188
ISSN:
0956-7135
Subject:
Citrus deliciosa; Citrus paradisi; Citrus sinensis; adulterated products; commodity foods; fruit juices; glucosides; grapefruits; hesperidin; horticultural crops; limonin; liquid chromatography; mandarins; metabolomics; naringin; tandem mass spectrometry; India
Abstract:
... Citrus fruits are one of the most important horticultural crops grown India, and a food commodity that is often targeted for mislabeling worldwide. Authentic citrus fruit samples (Kinnow mandrain (citrus nobilis x Citrus deliciosa), Jaffa and Mosambi orange (Citrus sinensis), and Red blush grapefruit (Citrus paradisi)) were obtained from the Indian Agriculture Research Institute and analysed by an ...
DOI:
10.1016/j.foodcont.2015.10.044

20. Benzofuran glycosides and coumarins from the bark of Streblus indicus (Bur.) Corner

Author:
Ruijie He; Yanjun Zhang; Liangdeng Wu; Hui Nie; Yan Huang; Buming Liu; Shengping Deng; Ruiyun Yang; Shuai Huang; Zhijie Nong; Jun Li; Haiyan Chen
Source:
Phytochemistry 2017 v.138 pp. 170-177
ISSN:
0031-9422
Subject:
Bacillus subtilis; Saccharomyces cerevisiae; Streblus; antimicrobial properties; bark; bladder; coumarin; cytotoxicity; glucosides; humans; hydroxylation; neoplasm cells; nuclear magnetic resonance spectroscopy; scopoletin; structure-activity relationships; umbelliferones
Abstract:
... Two pairs of rare benzofuran glucoside epimers, indicuses A and B and indicuses C and D, three biogenetically related compounds indicuses E–G, and one coumarin indicus H, as well as 11 known compounds, were isolated from the bark of Streblus indicus (Bur.) Corner. The structures of indicuses A–H were elucidated by NMR and MS data, as well as by CD. (S)-Marmesinin exhibited moderate antimicrobial a ...
DOI:
10.1016/j.phytochem.2017.01.011

21. Bioactive Glycosides from the Twigs of Litsea cubeba

Author:
Wang Ling-Yan; Chen Ming-Hua; Wu Jiang; Sun Hua; Liu Wei; Qu Yu-Hong; Li Yan-Cheng; Wu Yu-Zhuo; Li Rui; Zhang Dan; Wang Su-Juan; Lin Sheng
Source:
Journal of natural products 2017 v.80 no.6 pp. 1808-1818
ISSN:
1520-6025
Subject:
Litsea cubeba; X-ray diffraction; air drying; branches; circular dichroism spectroscopy; glucosides; human cell lines; inhibitory concentration 50; lignans; medicinal plants; nuclear magnetic resonance spectroscopy
Abstract:
... The air-dried twigs of Litsea cubeba, a traditional Chinese medicinal tree, afforded 10 new aromatic glycosides (1–10) and 26 known analogues. Their structures were assigned by extensive 1D and 2D NMR experiments, and the absolute configurations were resolved by chemical methods, electronic circular dichroism, specific rotation, and X-ray crystallographic analysis. Compound 4 is the first example ...
DOI:
10.1021/acs.jnatprod.6b01189

22. Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy

Author:
Anna Stojakowska; Janusz Malarz
Source:
Phytochemistry letters 2017 v.19 pp. 7-11
ISSN:
1874-3900
Subject:
Lactuca; caffeic acid; callus culture; chlorogenic acid; glucosides; lignans; sesquiterpenoid lactones
Abstract:
... A callus culture of Lactuca aculeata, except for commonly distributed caffeic acid derivatives typically found in the Asteraceae family (chlorogenic acid, methyl caffeate, 1,5- dicaffeoylquinic acid), yielded bioactive lignans: (+)-5-methoxybalanophonin, syringaresinol, (+)-balanophonin-9-O-β-glucopyranoside, (+) buddlenol A, (−)-dihydrodehydrodiconiferyl alcohol-4-O-β-glucopyranoside and (−)-dihy ...
DOI:
10.1016/j.phytol.2016.11.003

23. Bioactive steroids and sorbicillinoids isolated from the endophytic fungus Trichoderma sp. Xy24

Author:
Jin-Lian Zhao; Min Zhang; Ji-Mei Liu; Zhen Tan; Ri-Dao Chen; Ke-Bo Xie; Jun-Gui Dai
Source:
Journal of Asian natural products research 2017 v.19 no.10 pp. 1028-1035
ISSN:
1477-2213
Subject:
Human immunodeficiency virus 1; Trichoderma; cytotoxicity; endophytes; fungi; glucosides; human cell lines; inhibitory concentration 50; neuroglia; nitric oxide; spectral analysis; steroids; viruses
Abstract:
... A new steroid glucoside (1), along with nine known steroids (2–10) and four known sorbicillinoids (11–14), were isolated from the endophytic fungus Trichoderma sp. Xy24. Their structures were elucidated on the basis of spectroscopic data analyses and by comparison with reported data. Compounds 3 , 5–7 , 9 , 10 , and 13 exhibited significant inhibitory effects on HIV-1 virus with IC ₅₀ values rangi ...
DOI:
10.1080/10286020.2017.1285908

24. Bioengineering of the Plant Culture of Capsicum frutescens with Vanillin Synthase Gene for the Production of Vanillin

Author:
Marcus Jenn Yang Chee; Grantley W. Lycett; Teng-Jin Khoo; Chiew Foan Chin
Source:
Molecular biotechnology 2017 v.59 no.1 pp. 1-8
ISSN:
1073-6085
Subject:
Capsicum frutescens; biochemical pathways; bioengineering; biolistics; biotechnology; callus; consumer demand; explants; ferulic acid; genes; glucosides; high performance liquid chromatography; hot peppers; plant cultural practices; polymerase chain reaction; vanilla beans; vanillin
Abstract:
... Production of vanillin by bioengineering has gained popularity due to consumer demand toward vanillin produced by biological systems. Natural vanillin from vanilla beans is very expensive to produce compared to its synthetic counterpart. Current bioengineering works mainly involve microbial biotechnology. Therefore, alternative means to the current approaches are constantly being explored. This wo ...
DOI:
10.1007/s12033-016-9986-2

25. Biological characterization of epigallocatechin gallate complex with different steviol glucosides

Author:
Thi Thanh Hanh Nguyen; Nahyun M. Kim; Su-Cheong Yeom; Songhee Han; So-Hyung Kwak; Seong-Bo Kim; Jun-Seong Park; Il Kyoon Mok; Doman Kim
Source:
Biotechnology and bioprocess engineering 2017 v.22 no.5 pp. 512-517
ISSN:
1226-8372
Subject:
2,2-diphenyl-1-picrylhydrazyl; Clostridium difficile; Helicobacter pylori; Listeria monocytogenes; Salmonella Typhimurium; Staphylococcus aureus; Streptococcus mutans; alpha-amylase; alpha-glucosidase; blood glucose; cost effectiveness; epigallocatechin gallate; functional foods; glucose tolerance tests; glucosides; herbal tea; humans; maltose; mice; steviol; stevioside; sweeteners; water solubility
Abstract:
... Steviol glucosides (SGs) such as rubusoside (Ru), stevioside (Ste), rebaudioside A (RebA) and stevioside glucosides (SG) are herbal tea sweeteners that enhance the solubility and stability of a number of pharmaceutically important compounds. The complex of epigallocatechin gallate (EGCG) with 10% (w/v) each Ru, Ste, RebA or SG enhanced the water solubility of EGCG over 15 times to 345, 312, 341, o ...
DOI:
10.1007/s12257-017-0286-x

26. Biotransformation of soy whey into soy alcoholic beverage by four commercial strains of Saccharomyces cerevisiae

Author:
Jian-Yong Chua; Yuyun Lu; Shao-Quan Liu
Source:
International journal of food microbiology 2017 v.262 pp. 14-22
ISSN:
0168-1605
Subject:
Saccharomyces cerevisiae; alcoholic beverages; alcoholic fermentation; antioxidant activity; biotransformation; drainage systems; esters; ethanol; food industry; glucosides; isoflavones; liquid wastes; manufacturing; soy protein; tofu; whey; yeasts
Abstract:
... Soy whey is a liquid waste stream generated from tofu and soy protein manufacturing, and is commonly disposed of into the drainage system in food industry. Instead of disposing of soy whey as a waste, it could be used to produce alcoholic beverages. This study investigated the feasibility of converting soy whey into soy alcoholic beverage using four commercial Saccharomyces cerevisiae strains as a ...
DOI:
10.1016/j.ijfoodmicro.2017.09.007

27. The CYP79A1 catalyzed conversion of tyrosine to (E)-p-hydroxyphenylacetaldoxime unravelled using an improved method for homology modeling

Author:
Dario Vazquez-Albacete; Marco Montefiori; Stefan Kol; Mohammed Saddik Motawia; Birger Lindberg Møller; Lars Olsen; Morten H.H. Nørholm
Source:
Phytochemistry 2017 v.135 pp. 8-17
ISSN:
0031-9422
Subject:
Sorghum bicolor; active sites; arginine; biosynthesis; catalytic activity; cytochrome P-450; enzyme substrates; enzymes; glucosides; guidelines; models; prediction; site-directed mutagenesis; structure-activity relationships; threonine; tyrosine
Abstract:
... The vast diversity and membrane-bound nature of plant P450s makes it challenging to study the structural characteristics of this class of enzymes especially with respect to accurate intermolecular enzyme-substrate interactions. To address this problem we here apply a modified hybrid structure strategy for homology modeling of plant P450s. This allows for structural elucidation based on conserved m ...
DOI:
10.1016/j.phytochem.2016.11.013

28. Catalpol attenuates oxidative stress and promotes autophagy in TNF-α-exposed HAECs by up-regulating AMPK

Author:
Yukun Zhang; Changyuan Wang; Qining Yang; Yue Jin; Qiang Meng; Qi Liu; Yongguo Dai; Zhihao Liu; Kexin Liu; Huijun Sun
Source:
RSC advances 2017 v.7 no.83 pp. 52561-52572
ISSN:
2046-2069
Subject:
adenosine; adhesion; antioxidant activity; aorta; apoptosis; atherosclerosis; autophagy; catalpol; endothelial cells; epithelial cells; glucosides; humans; necrosis; neoplasms; oxidative stress; pathogenesis; protective effect; protein kinases; small interfering RNA; tumor necrosis factor-alpha
Abstract:
... Oxidative stress and autophagy dysfunction are critical factors in the pathogenesis of atherosclerosis. Adenosine 5′ monophosphate-activated protein kinase (AMPK) plays an important role in inhibiting oxidative stress and promoting autophagy. Catalpol, an iridoid glucoside extracted from the root of Rehmanniae glutinosa L, was reported to produce a potent antioxidant effect. However, the mechanism ...
DOI:
10.1039/c7ra09085d

29. Catechol glucosides act as donor/acceptor substrates of glucansucrase enzymes of Lactobacillus reuteri

Author:
Evelien M. te Poele; Vincent Valk; Tim Devlamynck; Sander S. van Leeuwen; Lubbert Dijkhuizen
Source:
Applied microbiology and biotechnology 2017 v.101 no.11 pp. 4495-4505
ISSN:
0175-7598
Subject:
Lactobacillus reuteri; alternansucrase; catechol; glucooligosaccharides; glucose; glucosides; polymerization; pyrogallol; resorcinol; sucrose
Abstract:
... Previously, we have shown that the glucansucrase GtfA-ΔN enzyme of Lactobacillus reuteri 121, incubated with sucrose, efficiently glucosylated catechol and we structurally characterized catechol glucosides with up to five glucosyl units attached (te Poele et al. in Bioconjug Chem 27:937–946, 2016). In the present study, we observed that upon prolonged incubation of GtfA-ΔN with 50 mM catechol and ...
DOI:
10.1007/s00253-017-8190-z
PubMed:
28258313
PubMed Central:
PMC5442262

30. Characterization and acid-catalysed depolymerization of condensed tannins derived from larch bark

Author:
Aibin Zhang; Jiongjiong Li; Shifeng Zhang; Youbing Mu; Wei Zhang; Jianzhang Li
Source:
RSC advances 2017 v.7 no.56 pp. 35135-35146
ISSN:
2046-2069
Subject:
Fourier transform infrared spectroscopy; Larix; Lewis bases; bark; beta-mercaptoethanol; catechin; depolymerization; desorption; epicatechin; epigallocatechin; esters; gallic acid; glucosides; hydrochloric acid; matrix-assisted laser desorption-ionization mass spectrometry; molecular weight; nuclear magnetic resonance spectroscopy; petrochemicals; proanthocyanidins; thermal stability; thermogravimetry
Abstract:
... Condensed tannins from larch bark extracts are a natural renewable and eco-friendly material and are potential substitutes for phenolic petrochemicals. However, the wide application of tannin is restricted by its low reactivity. Therefore, the goal of this study was to enhance the reactivity of larch tannin by depolymerization and determine optimal reaction conditions. The structures of larch tann ...
DOI:
10.1039/c7ra03410e

31. Characterization and seasonal variation of individual flavonoids in Zostera marina and Zostera noltii from Norwegian coastal waters

Author:
Kjersti Hasle Enerstvedt; Anders Lundberg; Inga Kjersti Sjøtun; Per Fadnes; Monica Jordheim
Source:
Biochemical systematics and ecology 2017 v.74 pp. 42-50
ISSN:
0305-1978
Subject:
Zostera marina; Zostera noltei; coastal water; coasts; glucosides; leaves; luteolin; rosmarinic acid; seasonal variation; winter; Norway
Abstract:
... The flavonoid content in leaves of Zostera marina and the endangered Zostera noltii, including mono- and disulphated flavonoids, from different sample localities were characterized. Seasonal variation of both individual and total flavonoid, as well as rosmarinic acid concentration were revealed. Minor amounts of luteolin 7-(6″-malonyl)glucoside (6) and apigenin7-(6″-malonyl)glucoside (11) were ide ...
DOI:
10.1016/j.bse.2017.08.003

32. Characterization of an exopolysaccharide with distinct rheological properties from Paenibacillus edaphicus NUST16

Author:
Jing Li; Haiyang Xu; Xiangnan Chen; Linxiang Xu; Rui Cheng; Jianfa Zhang; Shiming Wang
Source:
International journal of biological macromolecules 2017 pp. -
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; Paenibacillus; calcium chloride; carboxymethylcellulose; exopolysaccharides; glucosides; magnesium chloride; methylation; models; molecular weight; nuclear magnetic resonance spectroscopy; potassium chloride; sodium chloride; viscosity; xanthan gum
Abstract:
... Microbial exopolysaccharides (EPSs) have been commercially used for decades owing to their distinct rheological properties. New EPSs with special traits are being explored continuously. The strain Paenibacillus edaphicus NUST16 was isolated in this study. NUST16 produces 12.5g/L EPS after 72h cultivation in shaker flask. Moreover, the purified EPS, POS16, has the molecular weight of 1.2×107Da and ...
DOI:
10.1016/j.ijbiomac.2017.06.030

33. Characterization of metabolite profiles from the leaves of green perilla (Perilla frutescens) by ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry and screening for their antioxidant properties

Author:
Yeon Hee Lee; Bokyeong Kim; Soyoung Kim; Min-Sun Kim; Hyunji Kim; Seung-Ryul Hwang; Kyun Kim; Jin Hwan Lee
Source:
Yàowù shípǐn fēnxī 2017 v.25 no.4 pp. 776-788
ISSN:
1021-9498
Subject:
2,2-diphenyl-1-picrylhydrazyl; Perilla frutescens; antioxidant activity; drugs; flavonoids; free radicals; functional foods; glucosides; ionization; leaves; linolenic acid; mass spectrometry; metabolites; methanol; phenolic acids; rosmarinic acid; screening; triterpenoids; ultra-performance liquid chromatography; Korean Peninsula
Abstract:
... The objective of this research was to access the determination of metabolite profiles and antioxidant properties in the leaves of green perilla (Perilla frutescens), where these are considered functional and nutraceutical substances in Korea. A total of 25 compositions were confirmed as six phenolic acids, two triterpenoids, eight flavonoids, seven fatty acids, and two glucosides using an ultra hi ...
DOI:
10.1016/j.jfda.2016.09.003

34. Characterization of phenolic compounds in green and red oak‐leaf lettuce cultivars by UHPLC‐DAD‐ESI‐QToF/MS using MSE scan mode

Author:
Gabriela E. Viacava; Sara I. Roura; Luis A. Berrueta; Carmen Iriondo; Blanca Gallo; Rosa M. Alonso‐Salces
Source:
Journal of mass spectrometry 2017 v.52 no.12 pp. 873-902
ISSN:
1076-5174
Subject:
Lactuca sativa; apigenin; cultivars; diodes; freeze drying; glucosides; health promotion; ionization; ions; lettuce; mass spectrometry; polyphenols; ultra-performance liquid chromatography
Abstract:
... Lettuce (Lactuca sativa) is one of the most popular leafy vegetables in the world and constitutes a major dietary source of phenolic compounds with health‐promoting properties. In particular, the demand for green and red oak‐leaf lettuces has considerably increased in the last years but few data on their polyphenol composition are available. Moreover, the usage of analytical edge technology can pr ...
DOI:
10.1002/jms.4021

35. Characterization of sesame (Sesamum indicum L.) seed oil from Pakistan for phenolic composition, quality characteristics and potential beneficial properties

Author:
Alam Zeb; Bakhtiar Muhammad; Fareed Ullah
Source:
Journal of food measurement & characterization 2017 v.11 no.3 pp. 1362-1369
ISSN:
2193-4126
Subject:
Sesamum indicum; antioxidant activity; blood lipids; body weight; dietary supplements; dose response; ellagic acid; flavonoids; functional foods; glucosides; high performance liquid chromatography; histology; liver; polyphenols; rabbits; rosmarinic acid; sesame oil; sesame seed; Pakistan
Abstract:
... Sesame (Sesamum indicum, L.) seed oil was characterized for quality characteristics, phenolic composition and was supplemented to rabbits in different doses to assess potential beneficial effects. The phenolic profile of the oil was studied using reversed phase HPLC-DAD method. Sesame oil was rich in total phenolic contents, flavonoids, pigments and possess strong antioxidant activity. The HPLC-DA ...
DOI:
10.1007/s11694-017-9514-5

36. Characterizing the pigmented traditional rice cultivars grown in temperate regions of Kashmir (India) for free and bound phenolics compounds and in vitro antioxidant properties

Author:
Farhan M. Bhat; Charanjit S. Riar
Source:
Journal of cereal science 2017 v.76 pp. 253-262
ISSN:
0733-5210
Subject:
2,2-diphenyl-1-picrylhydrazyl; acetone; anthocyanins; antioxidant activity; color; cultivars; glucosides; lipid peroxidation; liquid chromatography; mass spectrometry; rice; temperate zones; India
Abstract:
... The purpose of the research was to identify the phenolic and flavonoid compounds of seven different traditional pigmented whole rice cultivars grown in the temperate regions of Kashmir so as to study their relationship with in vitro antioxidant capacities. The completely pigmented rice cultivars were found to have higher phenolic, flavonoid, anthocyanin contents and exhibited higher antioxidant ca ...
DOI:
10.1016/j.jcs.2017.06.018

37. Chemical Composition and Immuno‐Modulatory Effects of Urtica dioica L. (Stinging Nettle) Extracts

Author:
Marina Francišković; Raquel Gonzalez‐Pérez; Dejan Orčić; Fermín Sánchez de Medina; Olga Martínez‐Augustin; Emilija Svirčev; Nataša Simin; Neda Mimica‐Dukić
Source:
Phytotherapy research 2017 v.31 no.8 pp. 1183-1191
ISSN:
0951-418X
Subject:
chemoattractants; kaempferol; secretion; Urtica dioica; chemokine CCL2; glucosides; intestinal mucosa; dietary supplements; liquid chromatography; protective effect; isoquercitrin; rutin; oncogenes; phytopharmaceuticals; humans; linoleate 13S-lipoxygenase; aerial parts; lignans; immune response; chemical composition; monocytes; phenolic acids; inflammation; tandem mass spectrometry; prostaglandin synthase
Abstract:
... The purpose of this work was to determine the chemical profile of stinging nettle and to provide an insight into the mechanisms by which it ameliorates the immune response. Qualitative and quantitative liquid chromatography tandem mass spectrometry analyses indicated that phenolic acids (5‐O‐caffeoylquinic acid as dominant) and flavonol glycosides (rutin, isoquercitrin, and kaempferol 3‐O‐glucosid ...
DOI:
10.1002/ptr.5836

38. Chemical composition and evaluation of prolyl oligopeptidase and acetylcholinesterase inhibitory activities of Leonurus Sibiricus L. from Brazil

Author:
Lucimara L. Zachow; Janaína M. Ávila; Geovane A. Saldanha; Marco A. Mostardeiro; Ubiratan F. da Silva; Ademir F. Morel; Ionara I. Dalcol
Source:
Natural product research 2017 v.31 no.12 pp. 1459-1463
ISSN:
1478-6427
Subject:
Leonurus sibiricus; acetylcholinesterase; aerial parts; alkaloids; beta-sitosterol; chemical composition; diterpenoids; glucosides; hydrochloric acid; maceration; methanol; traditional medicine; Brazil
Abstract:
... Chemical investigation of the aerial parts of Leonurus sibiricus L. used in Brazilian folk medicine led to the identification of the following constituents: the labdane-type diterpenoid leojaponin, the phytosterols β-sitosterol and β-sitosterol glucoside and the alkaloid leonurine. The crude extracts obtained from methanol and methanol/1% HCl and pure compounds isolated from L. sibirius were inves ...
DOI:
10.1080/14786419.2016.1255890

39. Chemical constituents, radical scavenging activity and enzyme inhibitory capacity of fruits from Cotoneaster pannosus Franch.

Author:
Francisco LesThese authors equally contributed to the article.; Víctor López; Giovanni Caprioli; Romilde Iannarelli; Dennis Fiorini; Marzia Innocenti; Maria Bellumori; Filippo Maggi
Source:
Food & function 2017 v.8 no.5 pp. 1775-1784
ISSN:
2042-650X
Subject:
Cotoneaster; alpha-glucosidase; amine oxidase (flavin-containing); antioxidant activity; ascorbic acid; beta-carotene; chlorogenic acid; color; dietary supplements; fruit extracts; fruits; functional foods; glucosides; high performance liquid chromatography; ingredients; ornamental plants; shikimic acid; shrubs; tandem mass spectrometry; China
Abstract:
... Cotoneaster pannosus (Rosaceae) is a semievergreen shrub, producing globose dark red pomes, native to China and widely used as an ornamental plant all over the world. Despite its extensive cultivation, little information is available on the chemical composition and biological activities of its fruits. In this work, the analysis of the chemical composition of C. pannosus fruits, in terms of phenoli ...
DOI:
10.1039/c7fo00330g

40. Clerodane Diterpenoid Glucosides from the Stems of Tinospora sinensis

Author:
Jiang Huan; Zhang Gui-Jie; Liu Yan-Fei; Wang Heng-Shan; Liang Dong
Source:
Journal of natural products 2017 v.80 no.4 pp. 975-982
ISSN:
1520-6025
Subject:
Tinospora sinensis; cytotoxicity; diterpenoids; ethyl acetate; glucosides; inhibitory concentration 50; nitric oxide; spectral analysis; stems
Abstract:
... Ten new clerodane diterpenoid glucosides (1–10) and three known analogues (11–13) were isolated from an EtOAc extract of the stems of Tinospora sinensis. Spectroscopic analyses and chemical methods were used to elucidate the structures of these isolates. The absolute configurations of tinosinenosides A–C (1–3) were established by using experimental and calculated ECD data. Their cytotoxicity again ...
DOI:
10.1021/acs.jnatprod.6b00976

41. Comparative analysis of the in-vitro antioxidant activity and bioactive compounds of flaxseed in China according to variety and geographical origin

Author:
Qianchun Deng; Xiao Yu; Fangli Ma; Jiqu Xu; Fenghong Huang; Qingde Huang; Feng Sheng
Source:
International journal of food properties 2017 v.20 no.sup3 pp. S2708
ISSN:
1094-2912
Subject:
2,2-diphenyl-1-picrylhydrazyl; alpha-linolenic acid; antioxidant activity; antioxidants; bioactive compounds; chemometrics; glucosides; lignans; linseed; p-coumaric acid; phytosterols; principal component analysis; provenance; syringic acid; China
Abstract:
... The present study aimed to use a chemometric study to compare the in-vitro antioxidant activities and bioactive compounds of flaxseed based on the variety and geographical origins, and further explore the specific components constructed the endogenous antioxidant system of flaxseed in China. The differential contents of α-linolenic acid (35.83–58.91%), lignans (11.37–33.31 mg/g), total phenolic ac ...
DOI:
10.1080/10942912.2017.1402029

42. Comparative metabolism of mycophenolic acid by glucuronic acid and glucose conjugation in human, dog, and cat liver microsomes

Author:
J. E. Slovak; K. Mealey; M. H. Court
Source:
Journal of veterinary pharmacology and therapeutics 2017 v.40 no.2 pp. 123-129
ISSN:
0140-7783
Subject:
cats; dogs; glucose; glucosides; glucuronic acid; humans; liver microsomes; metabolism; metabolites; phenol
Abstract:
... Use of the immunosuppressant mycophenolic acid (MPA) in cats is limited because MPA elimination depends on glucuronidation, which is deficient in cats. We evaluated formation of major (phenol glucuronide) and minor (acyl glucuronide, phenol glucoside, and acyl glucoside) MPA metabolites using liver microsomes from 16 cats, 26 dogs, and 48 humans. All MPA metabolites were formed by human liver micr ...
DOI:
10.1111/jvp.12338
PubMed:
27301298
PubMed Central:
PMC5159325

43. Comparison of chemical composition of Hypericum perforatum and H. maculatum in Estonia

Author:
Linda Rusalepp; Ain Raal; Tõnu Püssa; Uno Mäeorg
Source:
Biochemical systematics and ecology 2017 v.73 pp. 41-46
ISSN:
0305-1978
Subject:
Hypericum perforatum; aerial parts; caffeic acid; catechin; chemical composition; chemotaxonomy; chlorogenic acid; epicatechin; flowers; glucosides; hyperforin; hypericin; isoquercitrin; kaempferol; leaves; metabolomics; myricetin; principal component analysis; quercetin; quercitrin; quinic acid; rutin; vanillic acid; Estonia
Abstract:
... Of numerous species belonging to the medicinally important genus Hypericum, only H. perforatum L. and H. maculatum Crantz grow widely in Estonia. A comparative biochemical systematics study of hypericins, hyperforins and other phenolics within Hypericum spp. growing in Estonia was performed. For comprehensive metabolomic investigation, 42 samples of H. perforatum and 16 samples of aerial parts of ...
DOI:
10.1016/j.bse.2017.06.004

44. Comparison of different in vitro micropropagation methods of Stevia rebaudiana B. including temporary immersion bioreactor (BIT®)

Author:
Karel Vives; Iván Andújar; José Carlos Lorenzo; Oscar Concepción; Martha Hernández; Maritza Escalona
Source:
Plant cell, tissue, and organ culture 2017 v.131 no.1 pp. 195-199
ISSN:
0167-6857
Subject:
Stevia rebaudiana; biomass; bioreactors; diabetes; glucosides; liquids; metabolites; micropropagation; shoots; steviol; sweeteners; vegetative propagation
Abstract:
... Stevia rebaudiana is beneficial to treat diabetes because of its low-calorie glucoside sweeteners. Natural and vegetative propagation are inefficient. In vitro techniques are an attractive alternative but low propagation and reproducibility rates have been reported. Therefore, different ways to increase natural sweetener production in vitro, such as BIT®, are required. We compared semisolid medium ...
DOI:
10.1007/s11240-017-1258-8

45. Comparison on extraction yield of sennoside A and sennoside B from senna (Cassia angustifolia) using conventional and non conventional extraction techniques and their quantification using a validated HPLC-PDA detection method

Author:
Tushar Dhanani; Raghuraj Singh; Nagaraja Reddy; A. Trivedi; Satyanshu Kumar
Source:
Natural product research 2017 v.31 no.9 pp. 1097-1101
ISSN:
1478-6427
Subject:
Senna alexandrina; ambient temperature; cold; glucosides; leaves; medicinal plants; microwave treatment; phytopharmaceuticals; pods; solvents; supercritical fluid extraction
Abstract:
... Senna is an important medicinal plant and is used in many Ayurvedic formulations. Dianthraquinone glucosides are the main bioactive phytochemicals present in leaves and pods of senna. The extraction efficiency in terms of yield and composition of the extract of senna prepared using both conventional (cold percolation at room temperature and refluxing) and non conventional (ultrasound and microwave ...
DOI:
10.1080/14786419.2016.1258562

46. Constituents from Vitex negundo var. heterophylla and their inhibition of nitric oxide production

Author:
Chongyue Qiu; Liang Tong; Ting Yuan; Fei Wang; Feng Zhao; Lixia Chen
Source:
Natural medicines 2017 v.71 no.1 pp. 292-298
ISSN:
1340-3443
Subject:
Vitex negundo; glucosides; inhibitory concentration 50; leaves; macrophages; molecular models; nitric oxide; nitric oxide synthase; nuclear magnetic resonance spectroscopy; phenol
Abstract:
... An iridoid glucoside, 10-p-hydroxybenzoyl-6β-hydroxyiridoid 1-O-β-D-(6′-O-p-hydroxybenzoyl)-glucopyranoside (1), and a phenol glucoside, 4-hydroxyphenethanol 3-O-β-D-(6′-O-p-hydroxybenzoyl)-glucopyranoside (2), along with nine known compounds (3–11) were isolated from the dried leaves of Vitex negundo var. heterophylla. Their structures were elucidated by extensive analysis of NMR spectra. All of ...
DOI:
10.1007/s11418-016-1032-y

47. Contrasting acclimation mechanisms of berry color variant grapevine cultivars (Vitis vinifera L. cv. Furmint) to natural sunlight conditions

Author:
Marianna Kocsis; Ferhan Ayaydin; László Kőrösi; Péter Teszlák; Lilla Radványi; Gábor Jakab; Éva Hideg
Source:
Acta physiologiae plantarum 2017 v.39 no.8 pp. 178
ISSN:
0137-5881
Subject:
Vitis vinifera; acclimation; caftaric acid; canopy; cell walls; chemical defenses; chloroplasts; color; confocal laser scanning microscopy; cultivars; glucosides; glycosylation; high performance liquid chromatography; leaf extracts; leaves; mesophyll; photosynthesis; polyphenols; quercetin; shade; solar radiation
Abstract:
... The acclimation mechanisms of two berry color variant grapevine leaves, Furmint White (FW) and Furmint Red (FR), to natural sunlight conditions were investigated comparing leaves from two distinct locations: at canopy surface (sun-exposed leaves) and in the inner layers (shaded leaves). We found that in contrast to FR leaves, sun-exposed FW leaves were thicker than shaded leaves due to thicker pal ...
DOI:
10.1007/s11738-017-2481-y

48. Cornusides A–O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis

Author:
Xian-Sheng Ye; Jun He; Yung-Chi Cheng; Lei Zhang; Hao-Yi Qiao; Xue-Ge Pan; Jia Zhang; Shu-Na Liu; Wei-Ku Zhang; Jie-Kun Xu
Source:
Journal of natural products 2017 v.80 no.12 pp. 3103-3111
ISSN:
1520-6025
Subject:
Cornus officinalis; chemical structure; fruits; glucosides; human cell lines; inhibitory concentration 50; iridoid glycosides; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Fifteen new and rare iridoid glucoside dimers, cornusides A–O (1–15), and 10 known iridoid glucosides (16–25) were isolated from the fruit of Cornus officinalis. These new chemical structures were established through spectroscopic analysis (UV, IR, HRESIMS, 1D and 2D NMR). Compounds 1–25 were tested for their inhibitory activities by measuring IL-6-induced STAT3 promoter activity in HepG2 cells, a ...
DOI:
10.1021/acs.jnatprod.6b01127

49. Correction to: CYP79 P450 monooxygenases in gymnosperms: CYP79A118 is associated with the formation of taxiphyllin in Taxus baccata

Author:
Katrin Luck; Qidong Jia; Meret Huber; Vinzenz Handrick; Gane Ka-Shu Wong; David R. Nelson; Feng Chen; Jonathan Gershenzon; Tobias G. Köllner
Source:
Plant molecular biology 2017 v.95 no.6 pp. 647
ISSN:
0167-4412
Subject:
Taxus baccata; glucosides; nitriles; oxidoreductases
Abstract:
... Due to an unfortunate turn of events, the funding note for Open Access publication was not properly provided in the original publication. Hence, the original article has been corrected. The opening line of the Acknowledgement section should read: ...
DOI:
10.1007/s11103-017-0674-9
PubMed:
29086190
PubMed Central:
PMC6061492

50. Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity

Author:
Niu Biao; Ke Chang-Qiang; Li Bo-Han; Li Yuanyuan; Yi Yongji; Luo Yongwei; Shuai Lin; Yao Sheng; Lin Li-Gen; Li Jia; Ye Yang
Source:
Journal of natural products 2017 v.80 no.5 pp. 1428-1435
ISSN:
1520-6025
Subject:
Siraitia grosvenorii; glucosides; luciferase; nuclear magnetic resonance spectroscopy
Abstract:
... Seven new cucurbitane glucosides, 11-oxomogrosides III E and IV (1 and 2), 11-oxoisomogroside V (3), 7-oxomogrosides III E and IV (4 and 5), and mogrosides VI A and VI B (6 and 7), were separated from the crude extract of Siraitia grosvenorii. The new structures were defined by analysis of their ¹H and ¹³C NMR, 2D NMR, and HRESIMS data. Especially, the band-selective constant time HSQC and band-se ...
DOI:
10.1021/acs.jnatprod.6b01086

51. Cultured roots of Xiphidium caeruleum: Phenylphenalenones and their biosynthetic and extractant-dependent conversion

Author:
Yu Chen; Christian Paetz; Riya C. Menezes; Bernd Schneider
Source:
Phytochemistry 2017 v.133 pp. 15-25
ISSN:
0031-9422
Subject:
Haemodoraceae; Musaceae; glucosides; isotope labeling; roots; stable isotopes
Abstract:
... Phytochemical investigation of root cultures of Xiphidium caeruleum (Haemodoraceae) resulted in the structure elucidation of five previously undescribed phenylphenalenone-type compounds, structure revision of a phenylphenalenone glucoside, and identification of nine additional constituents previously reported from other Haemodoraceae and Musaceae plants. The observed extractant-dependent metabolic ...
DOI:
10.1016/j.phytochem.2016.10.011

52. Cycloartane triterpenoid and its glucoside isolated from Cassia occidentalis

Author:
Shi-Fei LI; Shun-Lin LI
Source:
Chinese journal of natural medicines 2017 v.15 no.12 pp. 950-954
ISSN:
1875-5364
Subject:
Human immunodeficiency virus 1; Oriental traditional medicine; Senna occidentalis; antiviral properties; glucosides; mass spectrometry; median effective concentration; nuclear magnetic resonance spectroscopy; therapeutics; triterpenoids
Abstract:
... In the present study, one new cycloartane triterpenoid, named cycloccidentalic acid C (1) and its glucoside, cycloccidentaliside VI (2) were isolated from the whole plant of Cassia occidentalis. Their structures were elucidated by a combinational analyses of 1D and 2D NMR data and HRMS. Compound 2 showed modest anti-HIV-1 activity with EC50 value of 1.44 μmol·L⁻¹ and TI (Therapeutic Index) value o ...
DOI:
10.1016/S1875-5364(18)30012-8

53. Cytotoxic Cardiac Glycoside from the Parasitic Plant Cuscuta reflexa

Author:
Muhammad Ali Versiani; Asma Kanwal; Shaheen Faizi; Ahsana Dar Farooq
Source:
Chemistry of natural compounds 2017 v.53 no.5 pp. 915-922
ISSN:
0009-3130
Subject:
Cuscuta reflexa; anticarcinogenic activity; beta-sitosterol; bioassays; chemical structure; coumarins; cytotoxicity; fractionation; glucosides; nuclear magnetic resonance spectroscopy; parasitic plants; prostatic neoplasms; spectral analysis; stable isotopes; ursolic acid
Abstract:
... Bioassay guided fractionation of the cytotoxic extract of the plant Cuscuta reflexa, employing cytotoxic assay against a panel of 60 cell lines, led to the isolation of 13 compounds identified as odoroside H (1), 21-hydroxyodoroside H (2), neritaloside (3), strospeside (4), 16-β-hydroxydigitoxin (5), N-trans and cis feruloyl tyramines (6 and 7), ethyl caffeate (8), coumarins (9 and 10), ursolic ac ...
DOI:
10.1007/s10600-017-2154-5

54. Development and application of assay for determining β-glucosidase activity in human saliva

Author:
Lauren Stradwick; Debbie Inglis; Jennifer Kelly; Gary Pickering
Source:
Flavour 2017 v.6 no.1 pp. 1
ISSN:
2044-7248
Subject:
absorbance; alpha-cyclodextrin; beta-glucosidase; beverage industry; beverages; enzyme activity; flavor; glucosides; heat inactivation; mouth; saliva; sugars; wavelengths
Abstract:
... BACKGROUND: β-glucosidase is an enzyme important to flavour enhancement. It hydrolyzes glucosides to release aglycones—aroma precursors that are bound to a sugar molecule—thereby making them available to contribute to the flavour of foods and beverages. While there is strong interest within the food and beverage industry to optimizing flavour through the use of exogenous and endogenous glucosidase ...
DOI:
10.1186/s13411-017-0054-z

55. Divaccinosides A-D, four rare iridoid glucosidic truxillate esters from the leaves of Vaccinium bracteatum

Author:
Yong-Mei Ren; Chang-Qiang Ke; Chunping Tang; Sheng Yao; Yang Ye
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
Vaccinium bracteatum; X-ray diffraction; chemical structure; cycloaddition reactions; esters; glucosides; leaves; spectral analysis
Abstract:
... Divaccinosides A-D (1-4), four rare iridoid glucoside cyclodimers in the truxillate forms, were characterized from the leaves of Vaccinium bracteatum. They were presumably biosynthesized from two known iridoid glucoside monomers, vaccinoside (5) and 10-O-trans-p-coumaroyl-6α-hydroxyl-dihydromonotropein (6), via a [2+2] cycloaddition reaction. The structures of the new compounds were established by ...
DOI:
10.1016/j.tetlet.2017.05.013

56. Effect of Lignin Carbohydrate Complexes of Hardwood Hybrids on the Kraft Pulping Process

Author:
Vanessa Lopes Silva; Hasan Jameel; Fernando José Borges Gomes; Larisse Aparecida Ribas Batalha; Marcela Ribeiro Coura; Jorge Luiz Colodette
Source:
Journal of wood chemistry and technology 2017 v.37 no.1 pp. 52-61
ISSN:
1532-2319
Subject:
Eucalyptus; glucosides; hardwood; kraft pulp; kraft pulping; lignin; nuclear magnetic resonance spectroscopy; physicochemical properties; wood properties
Abstract:
... Lignin-carbohydrates complexes influence many chemical properties in the wood, such as difficult-to-remove lignin from Kraft pulps at the end of pulping due to the occurrence of lignin carbohydrates bonds. Therefore, this study aimed to study the influence of lignin-carbohydrate complexes on eucalyptus Kraft pulping. Spectroscopic techniques (¹³C NMR and HSQC-2D) were applied for the determination ...
DOI:
10.1080/02773813.2016.1235584

57. Effect of edible coatings with essential oils on the quality of red raspberries over shelf‐life

Author:
Marcos de Souza Gomes; Maria das Graças Cardoso; Ana Clara Garcia Guimarães; Adriana Cavaco Guerreiro; Custódia Maria Luís Gago; Eduardo Valério de Barros Vilas Boas; Cristina Maria Barrocas Dias; Ana Cristina Cabaça Manhita; Maria Leonor Faleiro; Maria Graça Costa Miguel; Maria Dulce Carlos Antunes
Source:
Journal of the science of food and agriculture 2017 v.97 no.3 pp. 929-938
ISSN:
0022-5142
Subject:
Citrus; Rubus idaeus; alginates; anthocyanins; bacteria; color; cyanidin; edible films; essential oils; free radicals; fruits; glucosides; lemons; molds (fungi); pelargonidin; raspberries; shelf life; singlet oxygen; storage time; yeasts
Abstract:
... BACKGROUND: The objective of the present work was to develop strategies for increasing the shelf‐life of red raspberries (Rubus idaeus L.), by preventing microorganism growth. RESULTS: Fruits coated with alginate plus lemon essential oil (0.2%) or orange essential oil (0.1%) after 15 days of storage had less red skin than the remaining samples. The less red color verified in these samples was also ...
DOI:
10.1002/jsfa.7817

58. Effect of heat processing on thermal stability and antioxidant activity of six flavonoids

Author:
Hind Chaaban; Irina Ioannou; Latifa Chebil; Manel Slimane; Christine Gérardin; Cédric Paris; Céline Charbonnel; Leila Chekir; Mohamed Ghoul
Source:
Journal of food processing and preservation 2017 v.41 no.5 pp. -
ISSN:
0145-8892
Subject:
activation energy; antioxidant activity; data collection; food processing; glucosides; glycosylation; heat; heat treatment; luteolin; models; naringin; processed foods; rutin; temperature; thermal stability
Abstract:
... The objective of this paper is on the one hand to study the effect of heat processing (30 to 130°C for 2 h) on the stability and antioxidant activity of six flavonoids (rutin, naringin, eriodictyol, mesquitol, luteolin, and luteolin 7‐O glucoside), and on the other hand to establish the relation structure–activity–stability of these compounds. The dependency on temperature of the six kinetics was ...
DOI:
10.1111/jfpp.13203

59. Effect of prolonged water stress on essential oil content, compositions and gene expression patterns of mono- and sesquiterpene synthesis in two oregano (Origanum vulgare L.) subspecies

Author:
Mohammad Reza Morshedloo; Lyle E. Craker; Alireza Salami; Vahideh Nazeri; Hyunkyu Sang; Filippo Maggi
Source:
Plant physiology and biochemistry 2017 v.111 pp. 119-128
ISSN:
0981-9428
Subject:
Origanum vulgare; acetates; beta-caryophyllene; biosynthesis; carvacrol; essential oils; flavonoids; gene expression; gene expression regulation; germacrene; glucosides; hydrodistillation; lipid content; monoterpenoids; oils; oregano; semiarid zones; sterols; tannins; thymol; water stress
Abstract:
... Origanum vulgare L., recognized throughout the world as a popular medicinal and flavoring herb, contains a wide array of medicinally active components, including phenolic glucosides, flavonoids, tannins, sterols and high amounts of terpenoids. Especially the latter are often extracted by hydrodistillation resulting in the so-called essential oil that is rich in monoterpenes (e.g. carvacrol, thymol ...
DOI:
10.1016/j.plaphy.2016.11.023

60. Effects of Juice Matrix and Pasteurization on Stability of Black Currant Anthocyanins during Storage

Author:
Gary Dobson; Gordon J. McDougall; Derek Stewart; Miguel Ángel Cubero; Reijo O. Karjalainen
Source:
Journal of food science 2017 v.82 no.1 pp. 44-52
ISSN:
0022-1147
Subject:
anthocyanins; apples; black currants; glucosides; pasteurization; peach juice; persimmons; phenols; storage temperature
Abstract:
... The effects of juice matrix and pasteurization on the stability of total phenols and especially total and individual anthocyanins were examined in black currant (BC) juice and mixtures with apple, persimmon, and peach juices at 4 °C and 20 °C. Total phenol content decreased in all juices at both temperatures but there was a trend to lower levels in unpasteurized over pasteurized juices. Difference ...
DOI:
10.1111/1750-3841.13575

61. Effects of photoperiod regimes and ultraviolet-C radiations on biosynthesis of industrially important lignans and neolignans in cell cultures of Linum usitatissimum L. (Flax)

Author:
Sumaira Anjum; Bilal Haider Abbasi; Joël Doussot; Alain Favre-Réguillon; Christophe Hano
Source:
Journal of photochemistry and photobiology 2017 v.167 pp. 216-227
ISSN:
1011-1344
Subject:
Linum usitatissimum; alcohols; antioxidant activity; bioactive compounds; biomarkers; biosynthesis; cell culture; flavonoids; flax; glucosides; lignans; medicinal properties; photoperiod; reversed-phase high performance liquid chromatography; ultraviolet radiation
Abstract:
... Lignans and neolignans are principal bioactive components of Linum usitatissimum L. (Flax), having multiple pharmacological activities. In present study, we are reporting an authoritative abiotic elicitation strategy of photoperiod regimes along with UV-C radiations. Cell cultures were grown in different photoperiod regimes (24h–dark, 24h–light and 16L/8D h photoperiod) either alone or in combinat ...
DOI:
10.1016/j.jphotobiol.2017.01.006

62. Efficient synthesis of α‐galactosyl oligosaccharides using a mutant Bacteroides thetaiotaomicron retaining α‐galactosidase (BtGH97b)

Author:
Masayuki Okuyama; Kana Matsunaga; Ken‐ichi Watanabe; Keitaro Yamashita; Takayoshi Tagami; Asako Kikuchi; Min Ma; Patcharapa Klahan; Haruhide Mori; Min Yao; Atsuo Kimura
Source:
FEBS journal 2017 v.284 no.5 pp. 766-783
ISSN:
1742-464X
Subject:
Bacteroides thetaiotaomicron; Lewis bases; alpha-galactosidase; anions; azides; fluorides; formates; glucosides; glycosidic linkages; glycosylation; hydrogen bonding; kinetics; mutants; oligosaccharides
Abstract:
... The preparation of a glycosynthase, a catalytic nucleophile mutant of a glycosidase, is a well‐established strategy for the effective synthesis of glycosidic linkages. However, glycosynthases derived from α‐glycosidases can give poor yields of desired products because they require generally unstable β‐glycosyl fluoride donors. Here, we investigate a transglycosylation catalyzed by a catalytic nucl ...
DOI:
10.1111/febs.14018

63. Enhancement of syringin contents in soybean seeds with seed-specific expression of a chimeric UGT72E3/E2 gene

Author:
Tackmin Kwon; Hye Jeong Kim; Su Yeong Yun; Jeongbeom Kim; Hyun Suk Cho; Jaesung Nam; Young-Soo Chung
Source:
Plant biotechnology reports 2017 v.11 no.6 pp. 439-447
ISSN:
1863-5466
Subject:
Arabidopsis; Glycine max; beta-conglycinin; enzymes; gene expression; genes; glucosides; high performance liquid chromatography; leaves; reverse transcriptase polymerase chain reaction; seeds; sinapyl alcohol; soybeans; transgenic plants
Abstract:
... Syringin, sinapyl alcohol 4-O-glucoside, is well known as a plant-derived bioactive monolignol glucoside. In Arabidopsis, recombinant chimeric protein UGT72E3/2 has been previously reported to lead to significantly higher syringin production than the parental enzymes UGT72E2 and UGT72E3. To enhance syringin content in Korean soybean (Glycine max L. ‘Kwangan’), we cloned the UGT72E3/2 gene under th ...
DOI:
10.1007/s11816-017-0464-5

64. Enzymatic biosynthesis of novel neobavaisoflavone glucosides via Bacillus UDP-glycosyltransferase

Author:
Tao MA; Yi-Qun DAI; Nan LI; Qiang HUO; Hong-Mei LI; Yu-Xin ZHANG; Zheng-Hao PIAO; Cheng-Zhu WU
Source:
Chinese journal of natural medicines 2017 v.15 no.4 pp. 281-287
ISSN:
1875-5364
Subject:
Oriental traditional medicine; biosynthesis; cytotoxicity; glucosides; glycosylation; high performance liquid chromatography; human cell lines; humans; inhibitory concentration 50; mass spectrometry; neoplasms; nuclear magnetic resonance spectroscopy; spectral analysis; transferases; water solubility
Abstract:
... The present study was designed to perform structural modifications of of neobavaisoflavone (NBIF), using an in vitro enzymatic glycosylation reaction, in order to improve its water-solubility. Two novel glucosides of NBIF were obtained from an enzymatic glycosylation by UDP-glycosyltransferase. The glycosylated products were elucidated by LC-MS, HR-ESI-MS, and NMR analysis. The HPLC peaks were int ...
DOI:
10.1016/S1875-5364(17)30045-6

65. Enzymatic glucosylation of unnatural naphthols by a promiscuous glycosyltransferase from Aloe arborescens

Author:
Kebo Xie; Yujiao Zhang; Ridao Chen; Dawei Chen; Lin Yang; Xia Liu; Jungui Dai
Source:
Tetrahedron letters 2017 v.58 pp. 2118-2121
ISSN:
0040-4039
Subject:
Aloe arborescens; chemical structure; cost effectiveness; drugs; enzymatic treatment; glucosides; glucosylation; glycosyltransferases; naphthols
Abstract:
... Enzymatic glucosylation of unnatural products by natural glycosyltransferases (GTs) has great potential in creating novel and bioactive glucosides. A new GT (AaGT3) from Aloe arborescens exhibited catalytic promiscuity and high efficiency to diverse unnatural naphthols. By combing the substrate flexibility and catalytic reversibility of AaGT3, a cost-effective enzymatic approach to novel and bioac ...
DOI:
10.1016/j.tetlet.2017.04.041

66. Enzymatic synthesis of chlorogenic acid glucoside using dextransucrase and its physical and functional properties

Author:
Seung-Hee Nam; Jin-A Ko; Woojin Jun; Young-Jung Wee; Marie K. Walsh; Kwang-Yeol Yang; Jin-Ho Choi; Jon-Bang Eun; Jeong Choi; Young-Min Kim; Songhee Han; Thi Thanh Hanh Nguyen; Doman Kim
Source:
Enzyme and Microbial Technology 2017 v.107 pp. 15-21
ISSN:
0141-0229
Subject:
Leuconostoc mesenteroides; antineoplastic activity; antioxidant activity; cell growth; chlorogenic acid; colorectal neoplasms; dextransucrase; food plants; functional properties; glucosides; glycosylation; heat; industrial applications; lipid peroxidation; mass spectrometry; nuclear magnetic resonance spectroscopy; polyphenols; response surface methodology; sucrose; water solubility
Abstract:
... Chlorogenic acid, a major polyphenol in edible plants, possesses strong antioxidant activity, anti-lipid peroxidation and anticancer effects. It used for industrial applications; however, this is limited by its instability to heat or light. In this study, we for the first time synthesized chlorogenic acid glucoside (CHG) via transglycosylation using dextransucrase from Leuconostoc mesenteroides an ...
DOI:
10.1016/j.enzmictec.2017.07.011

67. Enzymatic synthesis of novel corylifol A glucosides via a UDP-glycosyltransferase

Author:
Nan Li; Jian Miao; Jing Li; Yu-Ru Zhao; Hong-Mei Li; Yi-Qun Dai; Qiang Huo; Cheng-Zhu Wu; Tao Ma
Source:
Carbohydrate research 2017 pp. -
ISSN:
0008-6215
Subject:
Bacillus licheniformis; cytotoxicity; glucosides; glycosylation; humans; isoflavones; neoplasm cells; pH; temperature; water solubility
Abstract:
... Corylifol A, a member of the isoflavone subclass of isoflavonoids, has long been considered to have various biological activities. Here, we sought to synthesize corylifol A glucosides by the in vitro glucosylation reaction using the UDP-glycosyltransferase YjiC from Bacillus licheniformis DSM 13, and obtained two novel glucosides: corylifol A-4′,7-di-O-beta-d-glucopyranoside (1) and corylifol A-4′ ...
DOI:
10.1016/j.carres.2017.05.002

68. Enzymatic tailoring of oleuropein from Olea europaea leaves and product identification by HRMS/MS spectrometry

Author:
Efstratios Nikolaivits; Aikaterini Termentzi; Alexios-Leandros Skaltsounis; Nikolas Fokialakis; Evangelos Topakas
Source:
Journal of biotechnology 2017 v.253 pp. 48-54
ISSN:
0168-1656
Subject:
Myceliophthora thermophila; Olea europaea; beta-glucosidase; bioactive compounds; bioactive properties; branches; carboxylic ester hydrolases; cosmetics; diastereomers; food industry; glucosides; health promotion; hydrolysis; leaves; markets; nuclear magnetic resonance spectroscopy; oleuropein; substrate specificity
Abstract:
... Oleuropein, a bioactive compound found in all parts of olive tree, especially in leaves and branches, presents numerous health promoting properties that increase research and market interest the last few years. In addition, oleuropein degradation products, such as hydroxytyrosol, elenolic acid, and the aglycones also exhibit biological activities with different properties compared to the starting ...
DOI:
10.1016/j.jbiotec.2017.05.020

69. Eremophilane-type glucosides from the leaves of Ligularia calthifolia Maxim

Author:
Ludmila P. Ponomarenko; Sophia D. Ermolaeva; Roman V. Doudkin; Sergey A. Dyshlovoy; Petr G. Gorovoy
Source:
Phytochemistry letters 2017 v.21 pp. 264-268
ISSN:
1874-3900
Subject:
Ligularia; glucose; glucosides; humans; leaves; neoplasm cells; prostatic neoplasms; spectral analysis
Abstract:
... Three eremophilane-type glucosides (1–3) along with three known congeners alticolosides A, B and D (4–6) have been isolated from the leaves of Ligularia calthifolia Maxim. (Asteraceae). The structures of 1–3 have been elucidated by spectroscopic analysis as well as by chemical transformations. A distinctive feature of the compounds 1–3 is the presence of an acetyl group in the glucose residues. Th ...
DOI:
10.1016/j.phytol.2017.07.013

70. Ethnopharmacological investigations of the cardio-renal properties of a native species from the region of Pantanal, state of Mato Grosso do Sul, Brazil

Author:
Cleide Adriane Signor Tirloni; Francislaine Aparecida dos Reis Lívero; Rhanany Alan Calloi Palozi; Renan César Alves Silveira; Paulo César de Paula Vasconcelos; Roosevelt Isaias Carvalho Souza; Ariany Carvalho dos Santos; Valter Paes de Almeida; Jane Manfron Budel; Lauro Mera de Souza; Arquimedes Gasparotto Junior
Source:
Journal of ethnopharmacology 2017 v.206 pp. 125-134
ISSN:
0378-8741
Subject:
Acanthospermum hispidum; antagonists; chlorogenic acid; cyclic AMP; cyclic GMP; electrolytes; ethnobotany; excretion; glucosides; glycosylation; hypotension; indigenous species; liquid chromatography; males; mass spectrometry; medicinal plants; methylene blue; nitric oxide; phenolic compounds; potassium channels; prostaglandins; quality control; quercetin; rats; secondary metabolites; tetraethylammonium compounds; toxicity; traditional medicine; Brazil; Pantanal
Abstract:
... Acanthospermum hispidum DC. is an important medicinal herb that belongs to family Asteraceae, popularly used as a diuretic and hypotensive in the region of Pantanal, state of Mato Grosso do Sul, Brazil. Despite the relevance of this species throughout the country, there are no detailed studies about its possible ethnobotanical indication.To carry out a detailed ethnopharmacological investigation o ...
DOI:
10.1016/j.jep.2017.05.027

71. Eugenol specialty chemical production in transgenic poplar (Populus tremula × P. alba) field trials

Author:
Da Lu; Xianghe Yuan; Sung‐Jin Kim; Joaquim V. Marques; P. Pawan Chakravarthy; Syed G. A. Moinuddin; Randi Luchterhand; Barri Herman; Laurence B. Davin; Norman G. Lewis
Source:
Plant biotechnology journal 2017 v.15 no.8 pp. 970-981
ISSN:
1467-7644
Subject:
Populus alba; Populus tremula; acetates; alcohols; biochemical pathways; bioenergy; biomass; carbon; cross pollination; eugenol; felling; field experimentation; flowering; gene editing; gene expression; glucosides; indigenous species; leaves; metabolites; models; paper; pulp; stems; synthetic biology; transgenic plants; wood
Abstract:
... A foundational study assessed effects of biochemical pathway introduction into poplar to produce eugenol, chavicol, p‐anol, isoeugenol and their sequestered storage products, from potentially available substrates, coniferyl and p‐coumaryl alcohols. At the onset, it was unknown whether significant carbon flux to monolignols vs. other phenylpropanoid (acetate) pathway metabolites would be kineticall ...
DOI:
10.1111/pbi.12692
PubMed:
28064439
PubMed Central:
PMC5506655
CHORUS:
10.1111/pbi.12692
Chorus Open Access:
10.1111/pbi.12692

72. Exploration of genetic resources to improve the functional quality of virgin olive oil

Author:
Rosa García-Rodríguez; Angjelina Belaj; Carmen Romero-Segura; Carlos Sanz; Ana G. Pérez
Source:
Journal of functional foods 2017 v.38 pp. 1-8
ISSN:
1756-4646
Subject:
breeding programs; cultivars; fruits; genetic variation; glucosides; hydrolysis; new variety; oleuropein; olives; parents; phenolic compounds; virgin olive oil
Abstract:
... Phenolics are claimed to be one of the main responsible for the health benefits associated to the long term consumption of virgin olive oil (VOO). The variability of the phenolic composition was studied in an olive cultivar core collection which holds an extensive genetic diversity. The most abundant VOO phenolics were the secoiridoid derivatives resulting from the hydrolysis of oleuropein, ligstr ...
DOI:
10.1016/j.jff.2017.08.043

73. Extraction and Identification of Black Rice Polyphenolic Compounds by Reversed Phase High Performance Liquid Chromatography–Electrospray Ionization Mass Spectrometry

Author:
Feng Ying Xie; Wei Wei Bi; Xiao Jun Wang; Xiu Ling Zhang; Xiao Nan Zhang; Gui Xing Zhao; Qian Qian Liu
Source:
Journal of food processing and preservation 2017 v.41 no.5 pp. -
ISSN:
0145-8892
Subject:
Lewis acids; active oxygen species; black rice; caffeic acid; free radical scavengers; glucosides; high performance liquid chromatography; liquids; mass spectrometry; minerals; models; nutrients; phytopharmaceuticals; proanthocyanidins; whole grain foods
Abstract:
... Seven kinds of phenolic compounds in black rice were isolated and identified by reversed phase high performance liquid chromatography–electrospray ionization mass spectrometry. Proanthocyanidins glucoside which has the strongest ability of antioxidant and free radical scavenging was tentatively identified in black rice for the first time. By mass spectrometry in negative ion mode, three types of p ...
DOI:
10.1111/jfpp.13119

74. Extraction, identification and assessment of antioxidative compounds of bran extracts of traditional rice cultivars: An analytical approach

Author:
Farhan M. Bhat; Charanjit S. Riar
Source:
Food chemistry 2017 v.237 pp. 264-274
ISSN:
0308-8146
Subject:
2,2-diphenyl-1-picrylhydrazyl; antioxidant activity; bran; color; cultivars; flavonoids; glucosides; lipid peroxidation; liquid chromatography; mass spectrometry; oxidation; procyanidins; rice; thymol; ultrasonic treatment
Abstract:
... The antioxidative compounds were extracted by ultrasonic treatment of bran extracts of seven pigmented (completely) and non pigmented (sparsely) colored rice cultivars followed by assessment of their in vitro antioxidative capacity by LC-MS and oxidation/reduction assay based methods. A total of 40-compounds, 7-phenolic, 9-flavonoids, 9-hydroxycinammic acid derivatives, 3-hydroxybenzoic acid deriv ...
DOI:
10.1016/j.foodchem.2017.05.113

75. Facile preparation of water soluble curcuminoids extracted from turmeric (Curcuma longa L.) powder by using steviol glucosides

Author:
Thi Thanh Hanh Nguyen; Jinbeom Si; Choongil Kang; Byoungsang Chung; Donghwa Chung; Doman Kim
Source:
Food chemistry 2017 v.214 pp. 366-373
ISSN:
0308-8146
Subject:
2,2-diphenyl-1-picrylhydrazyl; Curcuma longa; Dengue virus; bioactive properties; bioavailability; glucosides; inhibitory concentration 50; pH; particle size; rhizomes; solubility; solubilization; steviol; stevioside; turmeric
Abstract:
... Curcuminoids from rhizomes of Curcuma longa possess various biological activities. However, low aqueous solubility and consequent poor bioavailability of curcuminoids are major limitations to their use. In this study, curcuminoids extracted from turmeric powder using stevioside (Ste), rebaudioside A (RebA), or steviol glucosides (SG) were solubilized in water. The optimum extraction condition by S ...
DOI:
10.1016/j.foodchem.2016.07.102

76. Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis

Author:
Qinglin He; Hua Yin; Jingjie Jiang; Yanfen Bai; Ning Chen; Shaowei Liu; Yibin Zhuang; Tao Liu
Source:
Journal of agricultural and food chemistry 2017 v.65 no.23 pp. 4691-4697
ISSN:
0021-8561
Subject:
Escherichia coli; Rhodiola; alcohols; biotransformation; culture media; fermentation; fungi; glucosides; honokiol; mutants; rosmarinic acid; spectroscopy; xanthones
Abstract:
... Three rosmarinic acid analogs produced by recombinant Escherichia coli, two xanthones from fungi and honokiol from plants, were explored as the substrates of E. coli harboring a glucosyltransferase mutant UGT73B6FS to generate phenolic glucosides. Six new and two known compounds were isolated from the fermentation broth of the recombinant strain of the feeding experiments, and the compounds were i ...
DOI:
10.1021/acs.jafc.7b00981

77. Flavanonol glucosides from the aerial parts of Agrimonia pilosa Ledeb. and their acetylcholinesterase inhibitory effects

Author:
U. Min Seo; Duc Hung Nguyen; Bing Tian Zhao; Byung Sun Min; Mi Hee Woo
Source:
Carbohydrate research 2017 pp. -
ISSN:
0008-6215
Subject:
Agrimonia; acetylcholinesterase; aerial parts; glucosides; inhibitory concentration 50; isomers; spectral analysis
Abstract:
... Two new flavanonol glucoside isomers, (2R,3S)-dihydrokaempferol 3-O-β-D-glucoside (1) and (2S,3R)-dihydrokaempferol 3-O-β-D-glucoside (2), were isolated from the aerial parts of Agrimonia pilosa Ledeb., along with eight known flavanonol glucosides (3–10). Their structures were determined on the basis of spectroscopic analysis. In addition, these compounds were evaluated to determine their acetylch ...
DOI:
10.1016/j.carres.2017.04.014

78. Flavonoid and Galloyl Glycosides Isolated from Saxifraga spinulosa and Their Antioxidative and Inhibitory Activities against Species That Cause Piroplasmosis

Author:
Badral Duger; Odonbayar Batsukh; Murata Toshihiro; Munkhjargal Tserendorj; Tuvshintulga Bumduuren; Igarashi Ikuo; Suganuma Keisuke; Inoue Noboru; Brantner Adelheid H.; Odontuya Gendaram; Sasaki Kenroh; Batkhuu Javzan
Source:
Journal of natural products 2017 v.80 no.9 pp. 2416-2423
ISSN:
1520-6025
Subject:
2,2-diphenyl-1-picrylhydrazyl; Babesia bigemina; Babesia bovis; Babesia caballi; Protozoa; Saxifraga; Theileria equi; aerial parts; antioxidant activity; babesiosis; flavonoids; glucosides; livestock; parasites; spectroscopy
Abstract:
... Eight new flavonoid-based 3′-O-β-d-glucopyranosides (1–8) and three new galloyl glucosides (9, 11, 12), were isolated from the aerial parts of Saxifraga spinulosa, along with 25 known compounds. The structures of the new compounds were elucidated by spectroscopic methods. Most of the isolated compounds exhibited potent DPPH radical-scavenging activities. Further, their inhibitory activities were e ...
DOI:
10.1021/acs.jnatprod.7b00142

79. Fluorescence detection of the transglycosylation activity of amylosucrase

Author:
Dong-Ho Seo; Jong-Hyun Jung; Cheon-Seok Park
Source:
Analytical biochemistry 2017 v.532 pp. 19-25
ISSN:
0003-2697
Subject:
Deinococcus geothermalis; Neisseria polysaccharea; biotransformation; chimerism; fluorescence; glucosides; high performance liquid chromatography; sucrose
Abstract:
... The purpose of this study was to investigate the novel fluorescence-based assay for the transglycosylation activity of amylosucrase (ASase). The transglycosylation activity of ASase from Deinococcus geothermalis (DGAS), ASase from Neisseria polysaccharea (NPAS), and DGAS-B (chimeric ASase wherein the B domain from DGAS was exchanged with the B domain of NPAS in a DGAS background) was applied to mo ...
DOI:
10.1016/j.ab.2017.05.028

80. Food Consumption and Electrophoresis of Some Isoenzymes in the Motor Muscles of Schistocerca gregaria Fed on Lotus corniculatus

Author:
G. Elsayed; S.M. Sayed; S.A.M. Amer; Y.N.S. Al Solaimi
Source:
African entomology 2017 v.25 no.1 pp. 1-12
ISSN:
1021-3589
Subject:
Lotus corniculatus; Schistocerca gregaria; Triticum aestivum; acid phosphatase; adults; alcohol dehydrogenase; allelochemicals; electrophoresis; enzyme activity; females; femur; food conversion; glucosides; herbivores; instars; isozymes; malate dehydrogenase; malic enzyme; muscles; nutrition assessment; nymphs; seedlings; toxicity; wheat; Sahara Desert
Abstract:
... The desert locust, Schistocerca gregaria (Forskål, 1775) (Orthoptera, Acrididae), may feed in the Sahara desert on Lotus corniculatus (Fabaceae), which is rich in linamarin, a cyanogenic glucoside that is usually toxic for herbivores. The relationship between food consumption and the activity of five isoenzymes in the motor muscles of desert locust was investigated. Nutritional indices were estima ...
DOI:
10.4001/003.025.0001

81. Four new ent-kaurene diterpene glucosides from Mikania micrantha

Author:
Li-Mei Dong; Xu-Chao Jia; Qing-Wen Luo; Yi-Ming Peng; Qiang Zhang; Bi Luo; Jian-Wen Tan
Source:
Phytochemistry letters 2017 v.20 pp. 155-159
ISSN:
1874-3900
Subject:
Gram-negative bacteria; Mikania micrantha; aerial parts; antibacterial properties; anticarcinogenic activity; chemical structure; diterpenoids; glucosides; humans; neoplasms; spectral analysis
Abstract:
... Phytochemical study on the aerial parts of Mikania micrantha led to the isolation of four new ent-kaurene diterpene glucosides, β-d-glucopyranosyl-15α-(3-hydroxy-3-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (1), β-d-glucopyranosyl-15α-(3-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (2), β-d-glucopyranosyl-15α-(2-methylbutanoyloxy)-9β-hydroxy-ent-16-kauren-19-oate (3), β-d-glucopyra ...
DOI:
10.1016/j.phytol.2017.04.029

82. Four new glycosides from the stems of Dendrobium fimbriatum Hook

Author:
Feng-Qing Xu; Wei-Wei Fan; Cheng-Ting Zi; Fa-Wu Dong; Dan Yang; Jun Zhou; Jiang-Miao Hu
Source:
Natural product research 2017 v.31 no.7 pp. 797-801
ISSN:
1478-6427
Subject:
Dendrobium; glucosides; spectral analysis; spectroscopy; stems
Abstract:
... Four new glucosides, named as gigantol-5- O - β - d -glucopyranoside (1), 9,10-dihydro-aphyllone A-5- O - β - d -glucopyranoside (2), ficusal-4- O - β - d -glucopyranoside (3), botrydiol-15- O - β - d -glucopyranoside (4), together with eight known compounds (5–12) were isolated from the n -BuOH extract of the stems of Dendrobium fimbriatum Hook. Their structures were elucidated by the analyses of ...
DOI:
10.1080/14786419.2016.1247076

83. Four new iridoid glucosides containing the furan ring from the fruit of Cornus officinalis

Author:
Jun He; Xian-Sheng Ye; Xiao-Xue Wang; Ya-Nan Yang; Pei-Cheng Zhang; Bing-Zhi Ma; Wei-Ku Zhang; Jie-Kun Xu
Source:
Fitoterapia 2017 pp. -
ISSN:
0367-326X
Subject:
Cornus officinalis; chemical structure; circular dichroism spectroscopy; glucosides; iridoid glycosides; neuroprotective effect; nuclear magnetic resonance spectroscopy; spectral analysis; sugars
Abstract:
... Four new and rare iridoid glucosides, cornusfuroside A–D (1–4), containing the furan ring were identified from water extract of the fruit of Cornus officinalis. These new chemical structures were determined through extensive spectroscopic analysis, including 1D and 2D NMR, IR, HRESIMS, experimental and calculated electronic circular dichroism (ECD). Notably, this study is the first report on the i ...
DOI:
10.1016/j.fitote.2017.06.003

84. Functional Analysis of an Uridine Diphosphate Glycosyltransferase Involved in the Biosynthesis of Polyphenolic Glucoside in Tea Plants (Camellia sinensis)

Author:
Xuecheng Zhao; Xinlong Dai; Liping Gao; Lina Guo; Juhua Zhuang; Yajun Liu; Xiubing Ma; Rui Wang; Tao Xia; Yunsheng Wang
Source:
Journal of agricultural and food chemistry 2017 v.65 no.50 pp. 10993-11001
ISSN:
1520-5118
Subject:
Camellia sinensis; Escherichia coli; aldehydes; amino acids; anthocyanins; biosynthesis; catalytic activity; complementary DNA; cyanidin; flavanones; flavonols; glucosides; glycosylation; humans; ingredients; isoelectric point; lignin; magnetism; molecular weight; plant health; polyphenols; taste; tea; transferases; uridine diphosphate
Abstract:
... Polyphenols are one of the largest groups of compounds that confer benefits to the health of plants and humans. Flavonol glycosides are a major ingredient of polyphenols in Camellia sinensis. Flavonol-3-O-glycosides are characteristic astringent taste compounds in tea infusion. A polyphenolic glycosyltransferase (CsUGT72AM1) belonging to cluster IIIb was isolated from the tea plant. The full-lengt ...
DOI:
10.1021/acs.jafc.7b04969

85. Functionalization of natural compounds by enzymatic fructosylation

Author:
Azucena Herrera-González; Gema Núñez-López; Sandrine Morel; Lorena Amaya-Delgado; Georgina Sandoval; Anne Gschaedler; Magali Remaud-Simeon; Javier Arrizon
Source:
Applied microbiology and biotechnology 2017 v.101 no.13 pp. 5223-5234
ISSN:
0175-7598
Subject:
alcohols; alkaloids; antioxidant activity; bioavailability; enzymes; flavonoids; glucosides; glycoconjugates; pharmacokinetics; solubility; sucrose
Abstract:
... Enzymatic fructosylation of organic acceptors other than sugar opens access to the production of new molecules that do not exist in nature. These new glycoconjugates may have improved physical-chemical and bioactive properties like solubility, stability, bioavailability, and bioactivity. This review focuses on different classes of acceptors including alkyl alcohols, aromatic alcohols, alkaloids, f ...
DOI:
10.1007/s00253-017-8359-5

86. Furan derivatives from Lannea kerstingii

Author:
Joseph Eric Mbasso Tameko; Jean Rodolphe Chouna; Pépin Nkeng-Efouet-Alango; Leon Azefack Tapondjou; Norbert Sewald
Source:
Phytochemistry letters 2017 v.20 pp. 282-284
ISSN:
1874-3900
Subject:
Lannea; Plasmodium falciparum; antiparasitic properties; bark; beta-sitosterol; glucosides; monoacylglycerols; nuclear magnetic resonance spectroscopy
Abstract:
... Two new furan derivatives, lannefuran A (1) and lannefuran B (2) were isolated from the stem bark extract of Lannea kerstingii Engl. & K. Krause together with five known compounds, namely: taraxerol, stigmast-4-en-3-one, monoglyceride of hexacosanoic acid, β-sitosterol and its glucoside. Their structures were determined by means of 1D and 2D NMR, IR, and HR–EI–MS spectra and comparison with the da ...
DOI:
10.1016/j.phytol.2017.04.040

87. Furofuran lignan glucosides from the leaves of Vitex negundo var. cannabifolia

Author:
Yue-Ting Li; Man-Man Li; Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dao-Ran Pang; Jiao Zheng; Yun-Fang Zhao; Peng-Fei Tu; Jun Li
Source:
Natural product research 2017 v.31 no.8 pp. 918-924
ISSN:
1478-6427
Subject:
Vitex negundo; glucosides; inhibitory concentration 50; leaves; lignans; nitric oxide; spectral analysis; spectroscopy
Abstract:
... Two new furofuran lignan glucosides, cannabilignin (1) and isocannabilignin (2), together with four known compounds (3 – 6), were isolated from the leaves of Vitex negundo var. cannabifolia . The structures of the isolates were elucidated by analysis of spectroscopic data. Compound 3 exhibited weak inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC ...
DOI:
10.1080/14786419.2016.1255887

88. Gas-phase pyrolysis of methyl glucosides and levoglucosan

Author:
Asuka Fukutome; Haruo Kawamoto; Shiro Saka
Source:
Journal of wood science 2017 v.63 no.3 pp. 295-306
ISSN:
1435-0211
Subject:
biomass; carbonyl compounds; cellulose; furans; gases; gasification; glucosides; isomers; pyrolysis; temperature
Abstract:
... Levoglucosan, the major intermediate in cellulose pyrolysis, is stable up to around 500 °C in the gas phase. To study whether this stability is a characteristic property of levoglucosan, the gas-phase reactivity was compared with those of methyl α- and β-glucosides at 200–500 °C (residence time 1.2–2.0 s). The methyl glucosides decomposed even at 200 and 300 °C to form levoglucosan exclusively. Th ...
DOI:
10.1007/s10086-017-1616-5

89. Gene cloning and expression of a glucoside 3-dehydrogenase from Sphingobacterium faecium ZJF-D6, and used it to produce N-p-nitrophenyl-3-ketovalidamine

Author:
Jian-Fen Zhang; Wei-Qing Chen; Hong Chen
Source:
World journal of microbiology & biotechnology 2017 v.33 no.2 pp. 21
ISSN:
0959-3993
Subject:
Escherichia coli; Halomonas; Sphingobacterium; amino acids; catalysts; galactosides; genes; glucosides; molecular cloning; pH; sugars; thermal stability
Abstract:
... In this study, we report the cloning and expression of a functional glucoside 3-dehydrogenase (G3DH) gene from Sphingobacterium faecium ZJF-D6. This gene is 1686 bp in length and encodes a peptide of 562 amino acids. The G3DH gene was successfully expressed in E. coli, and the recombinant enzyme could oxidize glucosides, galactosides and analogues at C-3 position. The sequence and multiple alignme ...
DOI:
10.1007/s11274-016-2187-0

90. Geniposide attenuates Staphylococcus aureus-induced pneumonia in mice by inhibiting NF-κB activation

Author:
Bin Yu; Yongbin Shen; Jiutao Qiao; Qingbo Cui
Source:
Microbial pathogenesis 2017 v.112 pp. 117-121
ISSN:
0882-4010
Subject:
Gardenia; Staphylococcus aureus; antioxidant activity; glucosides; histopathology; inflammation; interleukin-1beta; mice; myeloperoxidase; patients; pneumonia; protective effect; signal transduction; staining; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Staphylococcus aureus (S. aureus) is a major cause of pneumonia that often affects young and immunocompetent patients. Inflammation plays an important role in the development of S. aureus-induced pneumonia. Geniposide, a major iridoid glucoside component of gardenia fruit, has been reported to have anti-inflammatory and anti-oxidative effects. The purpose of this study was to investigate the prote ...
DOI:
10.1016/j.micpath.2017.09.050

91. a- Glucosidase inhibitors extracted from the roots of Polygonum multiflorum Thunb

Author:
Jian-Bo Yang; Jin-Ying Tian; Zhong Dai; Fei Ye; Shuang-Cheng Ma; Ai-Guo Wang
Source:
Fitoterapia 2017 v.117 pp. 65-70
ISSN:
0367-326X
Subject:
Reynoutria multiflora; ethanol; glucosides; inhibitory concentration 50; mass spectrometry; nuclear magnetic resonance spectroscopy; roots
Abstract:
... A novel stilbene glucoside, polygonumnolide D (1), and a novel dianthrone glycoside, polygonumnolide E (2), were isolated from a 70% EtOH extract of the dried roots of Polygonum multiflorum Thunb., together with six known compounds (3–8). Their structures were elucidated by 1D and 2D NMR as well as mass spectroscopy data. The isolated compounds were evaluated for their a-glucosidase inhibitory act ...
DOI:
10.1016/j.fitote.2016.11.009

92. Glucosylation of Smoke-Derived Volatiles in Grapevine (Vitis vinifera) is Catalyzed by a Promiscuous Resveratrol/Guaiacol Glucosyltransferase

Author:
Katja Hartl; Fong-Chin Huang; Ashok P. Giri; Kartrin Franz-Oberdorg; Johanna Frotscher; Yang Shao; Thomas Hoffmann; Wilfried Schwab
Source:
Journal of agricultural and food chemistry 2017 v.65 no.28 pp. 5681-5689
ISSN:
0021-8561
Subject:
Vitis vinifera; fermentation; forest fires; gene expression; genes; glucosides; glucosylation; glycosyltransferases; grapes; guaiacol; leaves; resveratrol; risk; small fruits; smoke; taint; tissues; winemaking; wines
Abstract:
... Vinification of grapes (Vitis vinifera) exposed to forest fire smoke can yield unpalatable wine due to the presence of taint compounds from smoke and the release of smoke derived volatiles from their respective glycosides during the fermentation process or in-mouth during consumption. To identify glycosyltransferases (GTs) involved in the formation of glycosidically bound smoke-derived volatiles w ...
DOI:
10.1021/acs.jafc.7b01886

93. Glycosylation and sulfation of 4-methylumbelliferone by Gliocladium deliquescens NRRL 1086

Author:
N. Fan; C. H. Du; J. Q. Xu; Y. X. Xu; B. Y. Yu; J. Zhang
Source:
Applied biochemistry and microbiology 2017 v.53 no.1 pp. 85-93
ISSN:
0003-6838
Subject:
Gliocladium; coumarin; culture media; enzymatic treatment; glucose; glucosides; glycosylation; metabolites; quercetin; spectroscopy; sulfates
Abstract:
... The aim of the study was to expand the substrate scope of Gliocladium deliquescens NRRL 1086 and generate coumarin glycosides using 4-methylumbelliferone (4-MU) as a substrate. The obtained results indicated that 4-MU can be metabolized to its glucoside (M1) and sulfate conjugate (M2), and the structures of the metabolites were elucidated by spectroscopic or enzymatic methods. Time course experime ...
DOI:
10.1134/S0003683817010033

94. Grain and Nutritional Quality Traits of Southwestern U.S. Blue Maize Landraces

Author:
Amol Nankar; F. Omar Holguin; M. Paul Scott; Richard C. Pratt
Source:
Cereal chemistry 2017 v.94 no.6 pp. 950-955
ISSN:
0009-0352
Subject:
Zea mays; amino acid composition; anthocyanins; color; corn; cyanidin; functional foods; genotype; glucosides; high performance liquid chromatography; landraces; near-infrared spectroscopy; nutritive value; oils; pelargonidin; seeds; starch; texture; New Mexico
Abstract:
... Anthocyanin‐rich Southwestern blue maize (Zea mays L.) landraces are receiving interest as functional foods, and commercial production is increasing. We determined variation in kernel color, anthocyanin content, texture, and selected compositional traits of representative varieties. In 2013, eight varieties were grown at four locations in New Mexico. Total kernel anthocyanin content (TAC) and comp ...
DOI:
10.1094/CCHEM-04-17-0079-R

95. HPLC-DAD analysis of arbutin produced from hydroquinone in a biotransformation process in Origanum majorana L. shoot culture

Author:
Ewa Skrzypczak-Pietraszek; Inga Kwiecień; Agnieszka Gołdyn; Jacek Pietraszek
Source:
Phytochemistry letters 2017 v.20 pp. 443-448
ISSN:
1874-3900
Subject:
Origanum majorana; biomass; biotransformation; culture flasks; freeze drying; glucosides; glucosylation; high performance liquid chromatography; hydroquinone; methanol; tissue culture
Abstract:
... The hydroquinone glucoside arbutin is a plant derived compound medically applied due to its uroantiseptic activity. It also has skin whitening properties and thus is widely used in dermatology and cosmetology. Origanum majorana L. (Lamiaceae) is known to produce arbutin, however the content of the compound in cultivated plants is very variable and low. Since plant cell and tissue cultures are capa ...
DOI:
10.1016/j.phytol.2017.01.009

96. Hepatoprotective effect of peony total glucosides and the underlying mechanisms in diabetic rats

Author:
Ling-Ling Xia; Qi-Jin Zhu; Yong-Gui Wu
Source:
Pharmaceutical biology 2017 v.55 no.1 pp. 2178-2187
ISSN:
1744-5116
Subject:
Paeonia lactiflora; adults; animal disease models; antioxidant activity; diabetes; endoplasmic reticulum stress; glucosides; hepatoprotective effect; histology; inflammation; lipids; liver; liver cirrhosis; macrophages; males; messenger RNA; plant extracts; protein content; protein synthesis; rats; roots; tumor necrosis factor-alpha
Abstract:
... Context: Total glucosides of peony (TGP), compounds extracted from the dried roots of Paeonia lactiflora Pall, have been reported to have anti-inflammatory and antioxidative activities. However, the protective effect of TGP on liver injury and the underlying mechanisms remains unknown in diabetic rats. Objectives: Current study investigates prevention of liver injury by TGP in diabetic rats and it ...
DOI:
10.1080/13880209.2017.1390589
PubMed:
29078720
PubMed Central:
PMC6130753

97. Hepatoprotective hemiterpene glycosides from the rhizome of Cibotium barometz (L.) J. Sm

Author:
Mei-Ping Xie; Lan Li; Hua Sun; An-Qi Lu; Bo Zhang; Jian-Gong Shi; Dan Zhang; Su-Juan Wang
Source:
Phytochemistry 2017 v.138 pp. 128-133
ISSN:
0031-9422
Subject:
Cibotium barometz; cytotoxicity; glucosides; hepatoprotective effect; liver; neuroprotective effect; nuclear magnetic resonance spectroscopy; rhizomes; spectral analysis
Abstract:
... Five previously undescribed hemiterpene glycosides, cibotiumbarosides E−I, and two known hemiterpene glucosides, were isolated from the rhizome of Cibotium barometz (L.) J. Sm. The structures of cibotiumbarosides E−I were established by 1D and 2D NMR spectroscopic analyses and HRMS. The absolute configuration of the aglycone of cibotiumbaroside E was assigned by calculated ECD with the TDDFT metho ...
DOI:
10.1016/j.phytochem.2017.02.023

98. High-level De novo biosynthesis of arbutin in engineered Escherichia coli

Author:
Xiaolin Shen; Jia Wang; Jian Wang; Zhenya Chen; Qipeng Yuan; Yajun Yan
Source:
Metabolic engineering 2017 v.42 pp. 52-58
ISSN:
1096-7176
Subject:
Candida parapsilosis; Escherichia coli; Rauvolfia serpentina; anti-inflammatory activity; antioxidants; biosynthesis; carbon; cosmetics; culture media; genes; glucose; glucosides; hydroquinone; shikimate pathway
Abstract:
... Arbutin is a hydroquinone glucoside compound existing in various plants. It is widely used in pharmaceutical and cosmetic industries owing to its well-known skin-lightening property as well as anti-oxidant, anti-microbial, and anti-inflammatory activities. Currently, arbutin is usually produced by plant extraction or enzymatic processes, which suffer from low product yield and expensive processing ...
DOI:
10.1016/j.ymben.2017.06.001

99. Higher Antioxidant Activity, Total Flavonols, and Specific Quercetin Glucosides in Two Different Onion (Allium cepa L.) Varieties Grown under Organic Production: Results from a 6-Year Field Study

Author:
Feiyue Ren; Kim Reilly; Joseph P. Kerry; Michael Gaffney; Mohammad Hossain; Dilip K. Rai
Source:
Journal of agricultural and food chemistry 2017 v.65 no.25 pp. 5122-5132
ISSN:
0021-8561
Subject:
2,2-diphenyl-1-picrylhydrazyl; Allium cepa; anthocyanins; antioxidant activity; bioactive compounds; glucosides; onions; organic production; organic soils; pesticide application; quercetin; soil treatment
Abstract:
... We carried out a 6-year study to assess the effect of conventional, organic, and mixed cultivation practices on bioactive compounds (flavonoids, anthocyanins) and antioxidant capacity in onion. Total flavonoids, total anthocyanins, individual flavonols, individual anthocyanins, and antioxidant activity were measured in two varieties (‘Hyskin’ and ‘Red Baron’) grown in a long-term split-plot factor ...
DOI:
10.1021/acs.jafc.7b01352

100. Hydrophobic, Hydrophilic, and Amphiphilic Polyglycocarbonates with Linear and Macrocyclic Architectures from Bicyclic Glycocarbonates Derived from CO2 and Glucoside

Author:
Pati Debasis; Feng Xiaoshuang; Hadjichristidis Nikos; Gnanou Yves
Source:
Macromolecules 2017 v.50 no.4 pp. 1362-1370
ISSN:
1520-5835
Subject:
carbon dioxide; catalysts; composite polymers; glucose; glucosides; hydrophilicity; hydrophobicity; nuclear magnetic resonance spectroscopy; polymerization; triethylene glycol; zwitterions
Abstract:
... Two bicyclic glycocarbonates were synthesized in five steps from α-methyl-d-glucoside without resorting to phosgene or to its derivatives for the first time. The 4- and 6-positions of glucose were modified to introduce a six-membered carbonate ring, using CO₂ as the carbonylating reagent; the 2- and 3-positions of the same glucoside substrate were first transformed into either methyl or triethylen ...
DOI:
10.1021/acs.macromol.6b02527