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You searched for: Publication Year 2017 Remove constraint Publication Year: 2017 Subject lignans Remove constraint Subject: lignans
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1. (-)-7(S)-hydroxymatairesinol protects against tumor necrosis factor-α-mediated inflammation response in endothelial cells by blocking the MAPK/NF-κB and activating Nrf2/HO-1

Author:
Di Yang; Chen-Xi Xiao; Zheng-Hua Su; Meng-Wei Huang; Ming Qin; Wei-Jun Wu; Wan-Wan Jia; Yi-Zhun Zhu; Jin-Feng Hu; Xin-Hua Liu
Source:
Phytomedicine 2017 v.32 pp. 15-23
ISSN:
0944-7113
Subject:
Western blotting; anti-inflammatory activity; antineoplastic activity; antioxidants; cardiovascular diseases; drugs; endothelial cells; fluorescent antibody technique; gene expression regulation; heme oxygenase (biliverdin-producing); inducible nitric oxide synthase; inflammation; interleukin-6; lignans; messenger RNA; mitogen-activated protein kinase; necrosis; pathogenesis; phosphorylation; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; superoxide dismutase; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Endothelial inflammation is an increasingly prevalent condition in the pathogenesis of many cardiovascular diseases. (-)-7(S)-hydroxymatairesinol (7-HMR), a naturally occurring plant lignan, possesses both antioxidant and anti-cancer properties and therefore would be a good strategy to suppress tumor necrosis factor-α (TNF-α)-mediated inflammation in vascular endothelial cells (VECs).: The objecti ...
DOI:
10.1016/j.phymed.2017.04.005

2. Absorption, distribution, metabolism, and excretion of [14C]sesamin in rats

Author:
Namino Tomimori; Tomohiro Rogi; Hiroshi Shibata
Source:
Molecular nutrition & food research 2017 v.61 no.8 pp. -
ISSN:
1613-4125
Subject:
absorption; autoradiography; bile; carbon; cytochrome P-450; excretion; feces; half life; intestinal microorganisms; kidneys; lignans; liver; metabolites; oral administration; pharmacokinetics; radioactivity; radionuclides; rats; sesame seed; tissue distribution; urine
Abstract:
... SCOPE: Sesamin is a major lignan in sesame seeds and has various physiological effects. Although metabolism of sesamin by cytochrome P450 or intestinal microflora has been reported, little is known concerning the mass balance, pharmacokinetics, and tissue distribution of sesamin. METHODS AND RESULTS: Absorption, distribution, metabolism, and excretion of [¹⁴C]sesamin were investigated after a sing ...
DOI:
10.1002/mnfr.201600844

3. Alashinols F and G, two lignans from stem bark of Syringa pinnatifolia

Author:
Xiao Feng; Guozhu Su; Yunyun Ye; Ruifei Zhang; Xinyao Yang; Bingzhao Du; Bing Peng; Pengfei Tu; Xingyun Chai
Source:
Natural product research 2017 v.31 no.13 pp. 1555-1560
ISSN:
1478-6427
Subject:
Syringa; anti-inflammatory activity; bark; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; traditional medicine
Abstract:
... Two new lignans, alashinols F and G (1 and 2), together with two known analogues (−)-secoisolariciresinol (3) and meso -secoisolariciresinol (4) were isolated from the stem bark of Syringa pinnatifolia , a Mongolian folk medicine with anti-myocardial ischaemic effects. Their structures were elucidated on basis of spectroscopic data analyses, including MS and 1D and 2D NMR, and their absolute confi ...
DOI:
10.1080/14786419.2017.1283500

4. Almond Polyphenols: Methods of Analysis, Contribution to Food Quality, and Health Promotion

Author:
Bradley W. Bolling
Source:
Comprehensive reviews in food science and food safety 2017 v.16 no.3 pp. 346-368
ISSN:
1541-4337
Subject:
aldehydes; almonds; antioxidant activity; antioxidants; antiviral properties; astringency; blanching; food quality; health promotion; hydrolysis; ingredients; isoflavones; lignans; lipid composition; lipid peroxidation; pasteurization; pigmentation; proanthocyanidins; roasting; shelf life; solvents; stilbenes; tannins; ultraviolet radiation; vitamin E
Abstract:
... Almond is a nutrient‐dense tree nut recognized for its favorable lipid profile, vitamin E content, and polyphenols. The objectives of this review were to determine the polyphenols reported in almond, summarize the methods of analysis, and determine the polyphenol contribution to almond quality and health‐promoting activity. Approximately 130 different polyphenols have been identified in almond, al ...
DOI:
10.1111/1541-4337.12260

5. Anti-HIV diphyllin glycosides from Justicia gendarussa

Author:
Hong-Jie Zhang; Emily Rumschlag-Booms; Yi-Fu Guan; Kang-Lun Liu; Dong-Ying Wang; Wan-Fei Li; Van Hung Nguyen; Nguyen Manh Cuong; Djaja Doel Soejarto; Harry H.S. Fong; Lijun Rong
Source:
Phytochemistry 2017 v.136 pp. 94-100
ISSN:
0031-9422
Subject:
Human immunodeficiency virus; Justicia gendarussa; RNA-directed DNA polymerase; antiretroviral agents; antiretroviral properties; arthritis; chemical composition; fractionation; glycosides; inhibitory concentration 50; lignans; medicinal plants; methanol; nucleosides; stems; China
Abstract:
... In a search for new anti-HIV active leads from over several thousands of plant extracts, we have identified a potent plant lead. The active plant is determined as Justicia gendarussa (Acanthaceae), a medicinal plant that has been used for the treatment of injury, arthritis and rheumatism in Asia including China. Our bioassay-guided fractionation of the methanol extract of the stems and barks of th ...
DOI:
10.1016/j.phytochem.2017.01.005
CHORUS:
10.1016/j.phytochem.2017.01.005
Chorus Open Access:
10.1016/j.phytochem.2017.01.005

6. Anti-biofilm activity against Staphylococcus aureus MRSA and MSSA of neolignans and extract of Piper regnellii

Author:
Lara Z.S. Brambilla; Eliana H. Endo; Diógenes A.G. Cortez; Benedito P. Dias Filho
Source:
Revista Brasileira de Farmacognosia 2017 v.27 no.1 pp. 112-117
ISSN:
0102-695X
Subject:
Piper; antibiotic resistance; antimicrobial properties; biofilm; disease control; lignans; methicillin; methicillin-resistant Staphylococcus aureus; methylene chloride; minimum inhibitory concentration; plankton
Abstract:
... Many infections worldwide are associated with bacterial biofilms. The effects of isolated neolignans (conocarpan and eupomathenoid-5) and the dichloromethane extract of Piper regnellii (Miq.) C. DC., Piperaceae, were tested against isolates of methicillin-resistant Staphylococcus aureus and methicillin-sensitive S. aureus biofilms and S. aureus planktonic cells. The dichloromethane extract present ...
DOI:
10.1016/j.bjp.2016.08.008

7. Anti-complementary constituents of Anchusa italica

Author:
Yu-zhen Hou; Kui-kui Chen; Xi-ling Deng; Ze-long Fu; Dao-feng Chen; Qi Wang
Source:
Natural product research 2017 v.31 no.21 pp. 2572-2574
ISSN:
1478-6427
Subject:
Anchusa azurea; alcohols; alkaloids; complement; flavonoids; fractionation; lignans; triterpenoids
Abstract:
... Activity-guided fractionation for complement inhibitors led to the isolation of 24 known compounds from Anchusa italica . Chemical types include eight megastigmane compounds, five triterpenoid compounds, five lignan compounds, three flavonoid compounds, two alkaloid compounds and one phenthyl alcohol compound. Among which, a lignan (medioresinol), an alkaloid (5-hydroxypyrrolidin-2-one) and a flav ...
DOI:
10.1080/14786419.2017.1320789

8. Anti-inflammatory effects of Forsythia suspensa in dextran sulfate sodium-induced colitis

Author:
Youn-Hwan Hwang; Dong-Gun Kim; Wei Li; Hye Jin Yang; Nam-Hui Yim; Jin Yeul Ma
Source:
Journal of ethnopharmacology 2017 v.206 pp. 73-77
ISSN:
0378-8741
Subject:
Forsythia suspensa; Oriental traditional medicine; anti-inflammatory activity; body weight changes; colitis; colon; dextran sulfate; diarrhea; edema; epithelium; flavonoids; histopathology; inflammation; interleukin-6; lignans; necrosis; therapeutics; triterpenoids; tumor necrosis factor-alpha
Abstract:
... Forsythia suspensa Fructus (FS) is used to treat various inflammatory disorders in traditional Oriental medicine, including gastrointestinal diseases, but its therapeutic potential in ulcerative colitis is unclear. Thus, we investigated any potential therapeutic effects of FS against intestinal inflammation and the bioactive constituents in FS.After the induction of colitis using 3% dextran sulfat ...
DOI:
10.1016/j.jep.2017.05.011

9. Anti-inflammatory neolignans from Epimedium pseudowushanese

Author:
Huihui Ti; Ping Wu; Liangxiong Xu; Xiaoyi Wei
Source:
Natural product research 2017 v.31 no.22 pp. 2621-2628
ISSN:
1478-6427
Subject:
Epimedium; anti-inflammatory activity; lignans; secretion; spectroscopy; tumor necrosis factor-alpha
Abstract:
... One new 8- O -4′ neolignan has been isolated from Epimedium pseudowushanese B. L. Guo, together with nine other known neolignans. The structures of these neolignans were elucidated using spectroscopic and chemical techniques, and their anti-inflammatory activities were also evaluated. The results of these experiments revealed that compound 6 was the most potent of the 10 different compounds tested ...
DOI:
10.1080/14786419.2017.1289200

10. Anti-neuroinflammatory asarone derivatives from the rhizomes of Acorus tatarinowii

Author:
Da-Peng Qin; Xiao-Lin Feng; Wei-Yang Zhang; Hao Gao; Xiao-Rui Cheng; Wen-Xia Zhou; Yang Yu; Xin-Sheng Yao
Source:
RSC advances 2017 v.7 no.14 pp. 8512-8520
ISSN:
2046-2069
Subject:
Acorus gramineus; X-ray diffraction; cell lines; cytotoxicity; enantiomers; lignans; mice; neuroglia; rhizomes; spectroscopy; tumor necrosis factor-alpha
Abstract:
... A novel 7-O-7′ type mesomeric neolignan, meso-asarolignan A (1), six pairs of new neolignan enantiomers, (±)-asarolignan B–G (2a/2b, 3a/3b, 4–6, 7a/7b), along with 16 known analogues (8–23) were isolated from the rhizomes of Acorus tatarinowii. The structures of the new compounds were elucidated by extensive analysis of spectroscopic, X-ray diffraction, and computational data. Compounds 1–3 repres ...
DOI:
10.1039/c6ra27786a

11. Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera

Author:
Hoai Thi Nguyen; Duc Viet Ho; Hung Quoc Vo; Anh Tuan Le; Hien Minh Nguyen; Takeshi Kodama; Takuya Ito; Hiroyuki Morita; Ain Raal
Source:
Pharmaceutical biology 2017 v.55 no.1 pp. 787-791
ISSN:
1744-5116
Subject:
Bacillus subtilis; Hedyotis; Mycobacterium smegmatis; Staphylococcus aureus; aerial parts; antibacterial properties; ceramides; chemical composition; ethyl acetate; fatty acids; glycosides; humans; lignans; mass spectrometry; methanol; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; oleanolic acid; quinones; screening; silica gel; steroids; therapeutics; traditional medicine
Abstract:
... Context: Hedyotis pilulifera (Pit.) T.N. Ninh (Rubiaceae) has been used in Vietnamese ethnomedicine; the methanol extract exhibited antibacterial activity in our preliminary screening. Objectives: In this study, compounds from H. pilulifera were isolated and their antibacterial activity in vitro was evaluated. Materials and methods: The aerial parts of H. pilulifera (1.4 kg) were extracted with Me ...
DOI:
10.1080/13880209.2017.1279673
PubMed:
28103726
PubMed Central:
PMC6130504

12. Antibacterial neolignans from the leaves of Melaleuca bracteata

Author:
Can Li; Hongxin Liu; Liyun Zhao; Weimin Zhang; Shengxiang Qiu; Xiaoyun Yang; Haibo Tan
Source:
Fitoterapia 2017 v.120 pp. 171-176
ISSN:
0367-326X
Subject:
Melaleuca; aldehydes; antibiotic resistance; antimicrobial properties; biochemical pathways; biomimetics; leaves; lignans; methicillin; methicillin-resistant Staphylococcus aureus; odors; spectral analysis
Abstract:
... Phytochemical study on the leaves of Melaleuca bracteata resulted in the isolation of ten compounds including three new neolignans, named melaleucins A–C (1–3). Among them, melaleucin B shares a rarely occurring nor-neolignan skeleton, and both melaleucins B and C bear a novel aldehyde moiety, which might also be response for the delicate fragrance of M. bracteata. Their structures were extensivel ...
DOI:
10.1016/j.fitote.2017.06.015

13. Antidiabetic effect of gomisin N via activation of AMP-activated protein kinase

Author:
Dae Young Jung; Ji-Hyun Kim; Hoyoung Lee; Myeong Ho Jung
Source:
Biochemical and biophysical research communications 2017 pp. -
ISSN:
0006-291X
Subject:
AMP-activated protein kinase; Schisandra chinensis; animal disease models; beta oxidation; biogenesis; blood glucose; fatty liver; genes; glucose; glucose tolerance; glucose transporters; glycemic effect; high fat diet; in vivo studies; insulin; lignans; metabolic syndrome; mice; mitochondria; myotubes; obesity; phosphorylation; plasma membrane; skeletal muscle
Abstract:
... Gomisin N (GN) is a lignan derived from Schisandra chinensis. AMP-activated kinase (AMPK) has gained attention as a therapeutic target for the treatment of metabolic syndrome. Previously, we reported that GN activated the AMPK pathway and ameliorated high-fat diet (HFD)-induced hepatic steatosis. In this study, we investigated the anti-diabetic effects of GN in C2C12 myotubes and HFD obese mice. G ...
DOI:
10.1016/j.bbrc.2017.10.120

14. Antioxidant and antimicrobial activity of linseed lignans and phenolic acids

Author:
Jan Kyselka; Dobrochna Rabiej; Miroslav Dragoun; František Kreps; Zuzana Burčová; Irena Němečková; Jana Smolová; Marie Bjelková; Aleksandra Szydłowska-Czerniak; Štefan Schmidt; Luděk Šarman; Vladimír Filip
Source:
European food research & technology 2017 v.243 no.9 pp. 1633-1644
ISSN:
1438-2377
Subject:
Gram-negative bacteria; Gram-positive bacteria; antimicrobial properties; antioxidants; bioactive compounds; caffeic acid; chromatography; ferulic acid; hydrolysis; levulinic acid; lignans; linseed; lipid peroxidation; mass spectrometry; median effective concentration; molds (fungi); oxidation; p-coumaric acid; pressing; reaction kinetics; secondary metabolites; solvents; stoichiometry; triacylglycerols; yeasts
Abstract:
... In this study, we present antioxidant and antimicrobial activity of isolated lignans freed of other bioactive compounds in comparison with dominant phenolic acids. The combinations of screw pressing, solvent extractions, acid-catalysed hydrolysis and flash chromatography were used to describe and isolate linseed phenolic compounds. Secoisolariciresinol, ferulic, p-coumaric and caffeic acids were t ...
DOI:
10.1007/s00217-017-2871-9

15. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense

Author:
Dan-Qi Li; Di Wang; Le Zhou; Ling-Zhi Li; Qing-Bo Liu; Ying-Ying Wu; Jing-Yu Yang; Shao-Jiang Song; Chun-Fu Wu
Source:
Journal of Asian natural products research 2017 v.19 no.5 pp. 519-527
ISSN:
1477-2213
Subject:
2,2-diphenyl-1-picrylhydrazyl; Bupleurum chinense; antioxidant activity; bioactive compounds; cytotoxicity; ethanol; fluorouracil; free radical scavengers; glucosides; inhibitory concentration 50; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... In the search for biologically active compounds from the roots of Bupleurum chinense D C., phytochemical investigation of its ethanol extract led to the isolation and identification of a new 8- O -4′ neolignan glucoside, saikolignanoside A (1), along with eight known lignans (2–9). Their structures were determined on the basis of IR, UV, HRESIMS, and NMR spectroscopic analyses. The antioxidant and ...
DOI:
10.1080/10286020.2016.1234456

16. Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine

Author:
Gustav Komlaga; Grégory Genta-Jouve; Sandrine Cojean; Rita A. Dickson; Merlin L.K. Mensah; Philippe M. Loiseau; Pierre Champy; Mehdi A. Beniddir
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
Phyllanthus fraternus; Plasmodium falciparum; Securinega; alkaloids; antimalarials; antiparasitic properties; chemical reactions; chemical structure; inhibitory concentration 50; lignans; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... The chemical investigation of the antimalarial plant Phyllanthus fraternus G. L. Webster (Phyllanthaceae) resulted in the discovery of the Securinega alkaloid (+)-allonorsecurinine (1), previously reported as a synthetic compound, together with the known ent-norsecurinine (2), nirurine (3), bubbialine (4), epibubbialine (5) and the lignan phyllanthin (6). The structure and absolute configuration o ...
DOI:
10.1016/j.tetlet.2017.08.045

17. Arctigenin attenuates ischemic stroke via SIRT1-dependent inhibition of NLRP3 inflammasome

Author:
Shimeng Zhang; Liangjun Jiang; Fengyuan Che; Yucheng Lu; Zhongxiang Xie; Hao Wang
Source:
Biochemical and biophysical research communications 2017 pp. -
ISSN:
0006-291X
Subject:
Arctium lappa; brain; infarction; inflammasomes; interleukin-18; interleukin-1beta; ischemia; lignans; neuroprotective effect; protein synthesis; rats; secretion; signal transduction; stroke; surgery; water content
Abstract:
... Arctigenin (ARC), a phenylpropanoid dibenzylbutyrolactone lignan derived from Arctium lappa L, has been reported to protect against cerebral ischemia injury in rats, but the underlying mechanism is unclear. In this study, we investigated whether ARC ameliorated ischemic stroke by inhibiting NLRP3 inflammasome-derived neuroinflammation and whether SIRT1 signaling was involved in this process. ARC ( ...
DOI:
10.1016/j.bbrc.2017.08.062

18. Arctigenin represses TGF-β-induced epithelial mesenchymal transition in human lung cancer cells

Author:
Yanrui Xu; Zhiyuan Lou; Seong-Ho Lee
Source:
Biochemical and biophysical research communications 2017 v.493 pp. 934-939
ISSN:
0006-291X
Subject:
Asteraceae; antineoplastic activity; beta catenin; cadherins; dose response; epithelium; humans; lignans; lung neoplasms; metastasis; mitogen-activated protein kinase; models; neoplasm cells; phosphorylation; snails; toxicity; transcription (genetics)
Abstract:
... Arctigenin (ARC) is a lignan that is abundant in Asteraceae plants, which show anti-inflammatory and anti-cancer activities. The current study investigated whether ARC affects cancer progression and metastasis, focusing on EMT using invasive human non-small cell lung cancer (NSCLC) cells. No toxicity was observed in the cells treated with different doses of ARC (12–100 μM). The treatment of ARC re ...
DOI:
10.1016/j.bbrc.2017.09.117

19. Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy

Author:
Ao Li; Xiaoxun Zhang; Mao Shu; Mingjun Wu; Jun Wang; Jingyao Zhang; Rui Wang; Peng Li; Yitao Wang
Source:
Phytomedicine 2017 v.30 pp. 28-41
ISSN:
0944-7113
Subject:
Arctium lappa; animal disease models; anti-inflammatory activity; antioxidant activity; atrophy; chemokine CCL2; collagen; disease prevention; epithelium; fibrosis; fruits; furans; histology; inflammation; interferon-gamma; interleukin-1beta; kidney diseases; lignans; lipid peroxidation; macrophages; messenger RNA; oxidative stress; phytopharmaceuticals; protein phosphorylation; rats; renal tubules; renoprotective effect; superoxide dismutase; transcription factor NF-kappa B; transforming growth factor beta 1; tumor necrosis factor-alpha
Abstract:
... Renal tubulointerstitial fibrosis (TIF) is commonly the final result of a variety of progressive injuries and leads to end-stage renal disease. There are few therapeutic agents currently available for retarding the development of renal TIF.The aim of the present study is to evaluate the role of arctigenin (ATG), a lignan component derived from dried burdock (Arctium lappa L.) fruits, in protecting ...
DOI:
10.1016/j.phymed.2017.03.003

20. Association between Dietary Share of Ultra-Processed Foods and Urinary Concentrations of Phytoestrogens in the US

Author:
Eurídice Martínez Steele; Carlos A. Monteiro
Source:
Nutrients 2017 v.9 no.3 pp. -
ISSN:
2072-6643
Subject:
National Health and Nutrition Examination Survey; additives; creatinine; daidzein; diet recall; dietary energy sources; education; food processing; genistein; geometry; household income; ingredients; lactones; lignans; minimally processed foods; models; nationalities and ethnic groups; nutrients; plant estrogens; United States
Abstract:
... The aim of this study was to examine the relationship between dietary contribution of ultra-processed foods and urinary phytoestrogen concentrations in the US. Participants from cross-sectional 2009–2010 National Health and Nutrition Examination Survey aged 6+ years, selected to measure urinary phytoestrogens and with one 24-h dietary recall were evaluated (2692 participants). Food items were clas ...
DOI:
10.3390/nu9030209
PubMed:
28264475
PubMed Central:
PMC5372872

21. Association between Urinary Phytoestrogens and C-reactive Protein in the Continuous National Health and Nutrition Examination Survey

Author:
Michael K. Reger; Terrell W. Zollinger; Ziyue Liu; Josette Jones; Jianjun Zhang
Source:
Journal of the American College of Nutrition 2017 v.36 no.6 pp. 434-441
ISSN:
1541-1087
Subject:
C-reactive protein; National Health and Nutrition Examination Survey; biomarkers; blood serum; cardiovascular diseases; confidence interval; inflammation; lignans; neoplasms; plant estrogens; risk; risk reduction; United States
Abstract:
... Objective : A reduced risk of some cancers and cardiovascular disease associated with phytoestrogen intake may be mediated through its effect on serum C-reactive protein (CRP; an inflammation biomarker). Therefore, this study examined the associations between urinary phytoestrogens and serum CRP. Methods : Urinary phytoestrogen and serum CRP data obtained from 6009 participants aged ≥ 40 years in ...
DOI:
10.1080/07315724.2017.1318722

22. Association between polyphenol intake and adherence to the Mediterranean diet in Sicily, southern Italy

Author:
Justyna Godos; Giuseppina Rapisarda; Stefano Marventano; Fabio Galvano; Antonio Mistretta; Giuseppe Grosso
Source:
NFS journal 2017 v.8 pp. 1-7
ISSN:
2352-3646
Subject:
Mediterranean diet; adults; anthocyanins; apigenin; databases; dietary nutrient sources; eating habits; ferulic acid; food intake; hesperetin; lignans; matairesinol; myricetin; naringenin; polyphenols; questionnaires; regression analysis; traditional foods; urban areas; Italy; Sicily
Abstract:
... Mediterranean diet has been demonstrated to exert beneficial effects toward various health outcomes. Among the compounds that may be responsible for such benefits, polyphenols have been proposed as potential candidates. The aim of this study was to evaluate whether dietary polyphenols were associated with adherence to the Mediterranean diet in a Sicilian cohort.A total of 1937 adults were recruite ...
DOI:
10.1016/j.nfs.2017.06.001

23. Association of Polyphenol Biomarkers with Cardiovascular Disease and Mortality Risk: A Systematic Review and Meta-Analysis of Observational Studies

Author:
Johanna Rienks; Janett Barbaresko; Ute Nöthlings
Source:
Nutrients 2017 v.9 no.4 pp. -
ISSN:
2072-6643
Subject:
biomarkers; blood; disease prevention; epidemiological studies; kaempferol; lactones; lignans; meta-analysis; metabolites; microorganisms; models; mortality; myocardial infarction; nutrition assessment; observational studies; polyphenols; systematic review; urine
Abstract:
... Epidemiologic studies have suggested an inverse association between flavonoids and cardiovascular disease (CVD). However, the results might have been influenced by the use of dietary assessment methods, which are error prone. The aim of this paper was to systematically review and analyse the literature for evidence of associations between polyphenol biomarkers and CVD and mortality risk in observa ...
DOI:
10.3390/nu9040415
PubMed:
28441720
PubMed Central:
PMC5409754

24. Associations between Both Lignan and Yogurt Consumption and Cardiovascular Risk Parameters in an Elderly Population: Observations from a Cross-Sectional Approach in the PREDIMED Study

Author:
Anna Creus-Cuadros; Anna Tresserra-Rimbau; Paola Quifer-Rada; Miguel Angel Martínez-González; Dolores Corella; Jordi Salas-Salvadó; Montse Fitó; Ramon Estruch; Enrique Gómez-Gracia; José Lapetra; Fernando Arós; Miquel Fiol; Emili Ros; Lluís Serra-Majem; Xavier Pintó; Juan José Moreno; Miguel Ruiz-Canela; Jose Vicente Sorli; Josep Basora; Helmut Schröder; Rosa Maria Lamuela-Raventós; PREDIMED Study Investigators
Source:
Journal of the Academy of Nutrition and Dietetics 2017 v.117 no.4 pp. 609-622.e1
ISSN:
2212-2672
Subject:
biomarkers; blood pressure; body mass index; cardiovascular diseases; cross-sectional studies; dairy consumption; diet study techniques; eating habits; elderly; glucose; human health; lignans; linear models; low density lipoprotein cholesterol; men; risk; triacylglycerols; waist circumference; women; yogurt
Abstract:
... The study of dietary patterns is gaining interest. Although the health benefits of yogurt and lignans have been investigated separately, to our knowledge there are no studies on their associative effects.The aim of this study was to evaluate a possible association between yogurt and lignans using biomarkers of cardiovascular disease risk in an elderly population.We conducted a cross-sectional anal ...
DOI:
10.1016/j.jand.2016.11.003

25. Asymmetric synthesis of furofurans

Author:
Manat Pohmakotr; Chutima Kuhakarn; Vichai Reutrakul; Darunee Soorukram
Source:
Tetrahedron letters 2017 pp. -
ISSN:
0040-4039
Subject:
bioactive properties; chemical reactions; chemical structure; lignans; stereochemistry; stereoselectivity
Abstract:
... Furofurans are one of the largest sub-types of classical lignans which have been found to possess a broad range of important biological activities. Tremendous efforts have been directed to develop synthetic methodologies for the synthesis of furofurans, especially in a stereoselective manner, due to their interesting bioactivities associated with the structural and stereochemical complexity. This ...
DOI:
10.1016/j.tetlet.2017.11.011

26. Bifidobacterium adolescentis INIA P784: The first probiotic bacterium capable of producing enterodiol from lignan extracts

Author:
Pilar Gaya; Ángela Peirotén; Margarita Medina; José Ma Landete
Source:
Journal of functional foods 2017 v.29 pp. 269-274
ISSN:
1756-4646
Subject:
Bifidobacterium adolescentis; bioavailability; biotechnology; functional foods; human health; intestinal microorganisms; lactic acid bacteria; lignans; linseed; matairesinol; metabolism; probiotics
Abstract:
... Lignans are phytoestrogens found in plant foods and especially in flax seeds. Although lignans present a low bioavailability, their transformation into the enterolignans enterodiol (END) and enterolactone (ENL) is associated with beneficial effects on human health. Lignan metabolism was studied in 90 lactic acid bacteria and bifidobacteria finding a wide distribution of the ability to deglycosylat ...
DOI:
10.1016/j.jff.2016.12.044

27. Bioactive Asarone-Derived Phenylpropanoids from the Rhizome of Acorus tatarinowii Schott

Author:
Gao En; Zhou Zheng-Qun; Zou Jian; Yu Yang; Feng Xiao-Lin; Chen Guo-Dong; He Rong-Rong; Yao Xin-Sheng; Gao Hao
Source:
Journal of natural products 2017 v.80 no.11 pp. 2923-2929
ISSN:
1520-6025
Subject:
2,2-diphenyl-1-picrylhydrazyl; Acorus gramineus; acarbose; acetylcholinesterase; alpha-glucosidase; antioxidant activity; antioxidants; benzene; drugs; enantiomers; enzyme inhibition; high performance liquid chromatography; inhibitory concentration 50; lignans; phenylpropanoids; rhizomes; spectral analysis
Abstract:
... Eight new (1a/1b, 2a, 3a, 4a/4b, and 5a/5b) and seven known (2b, 3b, and 6–10) asarone-derived phenylpropanoids, a known asarone-derived lignan (12), and four known lignan analogues (11 and 13–15) were isolated from the rhizome of Acorus tatarinowii Schott. The structures were elucidated via comprehensive spectroscopic analyses, modified Mosher’s method, and quantum chemical calculations. Compound ...
DOI:
10.1021/acs.jnatprod.7b00457

28. Bioactive Glycosides from the Twigs of Litsea cubeba

Author:
Wang Ling-Yan; Chen Ming-Hua; Wu Jiang; Sun Hua; Liu Wei; Qu Yu-Hong; Li Yan-Cheng; Wu Yu-Zhuo; Li Rui; Zhang Dan; Wang Su-Juan; Lin Sheng
Source:
Journal of natural products 2017 v.80 no.6 pp. 1808-1818
ISSN:
1520-6025
Subject:
Litsea cubeba; X-ray diffraction; air drying; branches; circular dichroism spectroscopy; glucosides; human cell lines; inhibitory concentration 50; lignans; medicinal plants; nuclear magnetic resonance spectroscopy
Abstract:
... The air-dried twigs of Litsea cubeba, a traditional Chinese medicinal tree, afforded 10 new aromatic glycosides (1–10) and 26 known analogues. Their structures were assigned by extensive 1D and 2D NMR experiments, and the absolute configurations were resolved by chemical methods, electronic circular dichroism, specific rotation, and X-ray crystallographic analysis. Compound 4 is the first example ...
DOI:
10.1021/acs.jnatprod.6b01189

29. Bioactive lignans and flavones with in vitro antioxidant and neuroprotective properties from Rubus idaeus rhizome

Author:
Yang Xu; Ling-Zhi Li; Qian Cong; Wei Wang; Xiao-Li Qi; Ying Peng; Shao-Jiang Song
Source:
Journal of functional foods 2017 v.32 pp. 160-169
ISSN:
1756-4646
Subject:
Rubus idaeus; antioxidant activity; antioxidants; ethanol; flavones; fruits; herbal medicines; leaves; lignans; neurodegenerative diseases; neuroprotective effect; rhizomes
Abstract:
... Rubus idaeus L. is caneberries from the genus Rubus that have been cultivated as food and herbal medicine, and is known to demonstrate strong antioxidant capability. In the present study, five new lignans, along with 13 known compounds, were isolated from ethanol extracts of R. idaeus rhizomes. An HPLC-MS/MS method was established and successfully applied to quantification of 14 compounds from lea ...
DOI:
10.1016/j.jff.2017.02.022

30. Bioactive lignans from the stems of Mappianthus iodoides

Author:
Zhi-Hua Jiang; Ling Chai; Yan-Ping Liu; Hong-Cong Qiu; Ting-Ting Wang; Xing-Yang Feng; Yi-Tong Wang; Ze-Hao Huang; Bu-Ming Liu; Yan-Hui Fu
Source:
Phytochemistry letters 2017 v.22 pp. 194-198
ISSN:
1874-3900
Subject:
anti-inflammatory activity; cortisol; inhibitory concentration 50; lignans; lipopolysaccharides; macrophages; mice; nitric oxide; spectroscopy; stems
Abstract:
... Two new lignans, mappianthines A (1) and B (2), along with ten known analogues (3-12), were isolated from the stems of Mappianthus iodoides. The structures with the absolute configurations of 1 and 2 were elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons their data with those reported in the literatures. All new compounds were evaluated for their ...
DOI:
10.1016/j.phytol.2017.10.012

31. Bioactive phenolics from in vitro cultures of Lactuca aculeata Boiss. et Kotschy

Author:
Anna Stojakowska; Janusz Malarz
Source:
Phytochemistry letters 2017 v.19 pp. 7-11
ISSN:
1874-3900
Subject:
Lactuca; caffeic acid; callus culture; chlorogenic acid; glucosides; lignans; sesquiterpenoid lactones
Abstract:
... A callus culture of Lactuca aculeata, except for commonly distributed caffeic acid derivatives typically found in the Asteraceae family (chlorogenic acid, methyl caffeate, 1,5- dicaffeoylquinic acid), yielded bioactive lignans: (+)-5-methoxybalanophonin, syringaresinol, (+)-balanophonin-9-O-β-glucopyranoside, (+) buddlenol A, (−)-dihydrodehydrodiconiferyl alcohol-4-O-β-glucopyranoside and (−)-dihy ...
DOI:
10.1016/j.phytol.2016.11.003

32. Bioactive phytochemicals in barley

Author:
Emmanuel Idehen; Yao Tang; Shengmin Sang
Source:
Yàowù shípǐn fēnxī 2017 v.25 no.1 pp. 148-161
ISSN:
1021-9498
Subject:
antioxidants; barley; beta-glucans; cardiovascular diseases; cholesterol; chronic diseases; diabetes; drugs; epidemiological studies; flavonoids; folic acid; lignans; neoplasms; obesity; phenolic acids; phytosterols; risk; risk reduction; whole grain foods
Abstract:
... Epidemiological studies have consistently shown that regular consumption of whole grain barley reduces the risk of developing chronic diseases. The presence of barley fiber, especially β-glucan in whole grain barley, has been largely credited for these health benefits. However, it is now widely believed that the actions of the fiber component alone do not explain the observed health benefits assoc ...
DOI:
10.1016/j.jfda.2016.08.002

33. Biotransformation of lignan glycoside to its aglycone by Woodfordia fruticosa flowers: quantification of compounds using a validated HPTLC method

Author:
Shikha Mishra; Vidhu Aeri
Source:
Pharmaceutical biology 2017 v.55 no.1 pp. 360-366
ISSN:
1744-5116
Subject:
Saraca asoca; Woodfordia fruticosa; bark; biotransformation; fermentation; flowers; glycosides; lignans; plant estrogens; solvents
Abstract:
... Context: Saraca asoca Linn. (Caesalpiniaceae) is an important traditional remedy for gynaecological disorders and it contains lyoniside, an aryl tetralin lignan glycoside. The aglycone of lyoniside, lyoniresinol possesses structural similarity to enterolignan precursors which are established phytoestrogens. Objectives: This work illustrates biotransformation of lyoniside to lyoniresinol using Wood ...
DOI:
10.1080/13880209.2016.1238948
PubMed:
27931157
PubMed Central:
PMC6130600

34. The Breast Cancer Resistance Protein (BCRP/ABCG2) influences the levels of enterolignans and their metabolites in plasma, milk and mammary gland

Author:
Dafne García-Mateos; Rocío García-Villalba; José Angel Marañón; Juan Carlos Espín; Gracia Merino; Ana I. Álvarez
Source:
Journal of functional foods 2017 v.35 pp. 648-654
ISSN:
1756-4646
Subject:
animal tissues; breast neoplasms; chemoprevention; dietary supplements; digestive system; females; functional foods; ingestion; lignans; mammary glands; metabolites; mice; milk; plant estrogens; polyphenols
Abstract:
... Lignans are phytoestrogens widely used in dietary supplements and functional foods. After oral ingestion, these polyphenols are metabolized to enterolignans, the main gut microbiota-derived metabolites with weak estrogenic/anti-estrogenic activities. The ABCG2 transporter is highly expressed in the mammary gland and could be responsible for enterolignan accumulation. We aimed here at evaluating th ...
DOI:
10.1016/j.jff.2017.06.038

35. Can sesame consumption improve blood pressure? A systematic review and meta‐analysis of controlled trials

Author:
Hossein Khosravi‐Boroujeni; Elham Nikbakht; Ernesta Natanelov; Saman Khalesi
Source:
Journal of the science of food and agriculture 2017 v.97 no.10 pp. 3087-3094
ISSN:
0022-5142
Subject:
blood pressure; databases; hypertension; lignans; meta-analysis; myocardial infarction; phytosterols; polyunsaturated fatty acids; renal failure; risk factors; stroke; systematic review
Abstract:
... Hypertension is a major risk factor for cardiovascular disease, myocardial infarction, stroke and renal failure. Sesame consumption may benefit blood pressure (BP) owing to its high polyunsaturated fatty acid, fibre, phytosterol and lignan contents. To clarify this, a systematic review and meta‐analysis of controlled trials was conducted. The PubMed (MEDLINE), Cumulative Index to Nursing and Allie ...
DOI:
10.1002/jsfa.8361

36. Changes in phenolic composition in olive tree parts according to development stage

Author:
Leila Abaza; Amani Taamalli; David Arráez-Román; Antonio Segura-Carretero; Alberto Fernández-Gutierrérez; Mokhtar Zarrouk; Nabil Ben Youssef
Source:
Food research international 2017 v.100 pp. 454-461
ISSN:
0963-9969
Subject:
Olea europaea; buds; cinnamic acid; detectors; flavonoids; flowers; freeze drying; fruit extracts; fruits; high performance liquid chromatography; leaves; lignans; mass spectrometry; methanol; olives; phenols; secoiridoids; tissues; Tunisia
Abstract:
... The aim of this study was to investigate the changes in the phenolic profile in different organs (buds, flowers, fruits and leaves) from Chemlali olive variety cultivated in the Center of Tunisia according to development stage. Phenolics recovery was carried out using aqueous methanol from freeze-dried powdered tissues. The extracts were then analyzed by using high performance liquid chromatograph ...
DOI:
10.1016/j.foodres.2016.12.002

37. Characterization of Phase I and Phase II Hepatic Metabolism and Reactive Intermediates of Larrea nitida Cav. and Its Lignan Compounds

Author:
Hyesoo Jeong; Soolin Kim; Jimin Lee; Jin Young Park; Wenmei Zhou; Xiyuan Liu; So Dam Kim; Yun Seon Song; Chang‐Young Jang; Sei‐Ryang Oh; Sangho Choi; Minsun Chang
Source:
Phytotherapy research 2017 v.31 no.1 pp. 140-151
ISSN:
0951-418X
Subject:
Larrea; NADP (coenzyme); antioxidants; bioactive compounds; cytochrome P-450; enzymes; glutathione; inhibitory concentration 50; isozymes; lignans; liver microsomes; metabolism; metabolites; methanol; models; nicotinamide; nordihydroguaiaretic acid; phosphates; rats; toxicity; uridine; Chile
Abstract:
... Larrea nitida Cav. (LNC), which belongs to the family Zygophyllaceae, is widely indigenous and used in South America to treat various pathological conditions. It contains the antioxidant and antiinflammatory but toxic nordihydroguaiaretic acid (NDGA) as well as O‐methylated metabolite of NDGA (MNDGA) as bioactive compounds. The hepatic metabolism‐based toxicological potential of extracts of LNC (L ...
DOI:
10.1002/ptr.5742

38. Characterization of some potential medicinal plants from Central Europe by their antioxidant capacity and the presence of metal elements

Author:
Michal Tupec; Veronika Hýsková; Kateřina Bělonožníková; Jakub Hraníček; Václav Červený; Helena Ryšlavá
Source:
Food bioscience 2017 v.20 pp. 43-50
ISSN:
2212-4292
Subject:
2,2-diphenyl-1-picrylhydrazyl; Agrimonia eupatoria; Mentha piperita; Origanum vulgare; antioxidant activity; calcium; diet; drinking; electrons; flavonoids; herbal tea; humans; hydrogen; lignans; magnesium; medicinal plants; phenolic acids; plant extracts; polyphenols; potassium; selenium; sodium; sodium chloride; stilbenes; zinc; Central European region
Abstract:
... Plants contain polyphenolic compounds such as phenolic acids, flavonoids, stilbenes, lignans, etc., which are endowed with antioxidant properties. The aim of this study was to correlate the total phenolic compound and flavonoid content of 15 medicinal plants with their antioxidant properties and to determine some important essential elements (Na, K, Ca, Mg, Zn, Se). The antioxidant capacity was te ...
DOI:
10.1016/j.fbio.2017.08.001

39. Chemical Composition and Immuno‐Modulatory Effects of Urtica dioica L. (Stinging Nettle) Extracts

Author:
Marina Francišković; Raquel Gonzalez‐Pérez; Dejan Orčić; Fermín Sánchez de Medina; Olga Martínez‐Augustin; Emilija Svirčev; Nataša Simin; Neda Mimica‐Dukić
Source:
Phytotherapy research 2017 v.31 no.8 pp. 1183-1191
ISSN:
0951-418X
Subject:
chemoattractants; kaempferol; secretion; Urtica dioica; chemokine CCL2; glucosides; intestinal mucosa; dietary supplements; liquid chromatography; protective effect; isoquercitrin; rutin; oncogenes; phytopharmaceuticals; humans; linoleate 13S-lipoxygenase; aerial parts; lignans; immune response; chemical composition; monocytes; phenolic acids; inflammation; tandem mass spectrometry; prostaglandin synthase
Abstract:
... The purpose of this work was to determine the chemical profile of stinging nettle and to provide an insight into the mechanisms by which it ameliorates the immune response. Qualitative and quantitative liquid chromatography tandem mass spectrometry analyses indicated that phenolic acids (5‐O‐caffeoylquinic acid as dominant) and flavonol glycosides (rutin, isoquercitrin, and kaempferol 3‐O‐glucosid ...
DOI:
10.1002/ptr.5836

40. Chemical Composition and UVA-Protecting Activity of Extracts from Ligustrum vulgare and Olea europaea Leaves

Author:
Monika E. Czerwińska; Katarzyna Duszak; Andrzej Parzonko; Anna K. Kiss
Source:
Acta biologica Cracoviensia 2017 v.58 no.2 pp. 45-55
ISSN:
1898-0295
Subject:
Ligustrum vulgare; Olea europaea; apoptosis; cell viability; chemical composition; fibroblasts; flavonoids; herbal medicines; humans; leaf extracts; leaves; lignans; models; oleuropein; olives; phenylpropanoids; propidium; protective effect; reactive oxygen species; skin diseases; staining; Mediterranean region; Northern European region
Abstract:
... Plants belonging to the family Oleaceae have been traditionally used in treatment of various inflammatory skin disorders. One of the most well-known species is Olea europaea L. (olive), cultivated in the Mediterranean countries. Another species is Ligustrum vulgare L. (common privet), occurring particularly in Northern Europe and Asia.The aim of the study was a comparison of the composition of aqu ...
DOI:
10.1515/abcsb-2016-0016

41. Chemical Constituents and Anti-inflammatory Principles from the Fruits of Forsythia suspensa

Author:
Kuo Ping-Chung; Hung Hsin-Yi; Nian Chi-Wei; Hwang Tsong-Long; Cheng Ju-Chien; Kuo Daih-Huang; Lee E-Jian; Tai Shih-Huang; Wu Tian-Shung
Source:
Journal of natural products 2017 v.80 no.4 pp. 1055-1064
ISSN:
1520-6025
Subject:
Forsythia suspensa; anti-inflammatory activity; chemical composition; diterpenoids; elastase; fruits; inhibitory concentration 50; lignans; spectroscopy; superoxide anion; triterpenoids
Abstract:
... Fifty compounds were isolated from the fruits of Forsythia suspensa, including 13 new compounds characterized as eight new diterpenoids (1–8), three new lignans (9–11), a new iridoid (12), and a new triterpenoid (13). Their structures were established on the basis of spectroscopic and spectrometric analysis. Most of the isolated compounds were examined for their anti-inflammatory activity in vitro ...
DOI:
10.1021/acs.jnatprod.6b01141

42. Chemical constituents from Piper boehmeriifolium (Miq.) Wall. ex C. DC

Author:
Tie Liu; Qian Liang; Xin-Min Zhang; Gen-Qian Li; Bo Xu; Wen-Hui Xu
Source:
Biochemical systematics and ecology 2017 v.75 pp. 27-30
ISSN:
0305-1978
Subject:
Piper; alkaloids; chemical composition; chemotaxonomy; diterpenoids; lignans; monoterpenoids; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... The chemical investigation of whole plants Piper boehmeriifolium (Miq.) Wall. ex C. DC. led to the isolation of 22 compounds, including two lignans (1–2), sixteen amide alkaloids (3–18), one diterpene (19), two monoterpenes (20–21), and one phenylpropanoid (22). Their structures were elucidated by extensive spectroscopic analyses including NMR, MS, and by comparison with the literature. Compounds ...
DOI:
10.1016/j.bse.2017.11.003

43. Chemical profiling and antioxidant evaluation of Yangxinshi Tablet by HPLC–ESI-Q-TOF-MS/MS combined with DPPH assay

Author:
Junfeng Zhu; Xiaojiao Yi; Jinghui Zhang; Shuqing Chen; Yongjiang Wu
Source:
Journal of chromatography 2017 v.1060 pp. 262-271
ISSN:
1570-0232
Subject:
2,2-diphenyl-1-picrylhydrazyl; Oriental traditional medicine; alkaloids; anthraquinones; antioxidant activity; ascorbic acid; cardiovascular diseases; chemical composition; clinical trials; coumarin; flavanoids; free radical scavengers; glycosides; high performance liquid chromatography; inhibitory concentration 50; lignans; mass spectrometry; mechanism of action; oral administration; rapid methods; rats; salvianolic acid; screening; triterpenoids
Abstract:
... Yangxinshi Tablet (YXST) is a Chinese patent medicine commonly used to treat cardiovascular diseases. However, its detailed chemical basis and mechanisms of action have not been clarified. In this study, high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (HPLC–ESI-Q-TOF-MS) was applied for comprehensive analysis of the chemical c ...
DOI:
10.1016/j.jchromb.2017.06.022

44. Chemical study of Anthospermum emirnense (Rubiaceae)

Author:
Tiana Sylvia Ralambonirina Rasoarivelo; Raphaël Grougnet; Sylvie Michel; Christiane Rakotobe Guillou; Brigitte Deguin
Source:
Biochemical systematics and ecology 2017 v.70 pp. 186-191
ISSN:
0305-1978
Subject:
Rubiaceae; aerial parts; anthraquinones; benzoic acids; chemotaxonomy; coumarin; flavonoids; iridoid glycosides; lignans; triterpenoids
Abstract:
... Chemical study of the aerial parts of Anthospermum emirnense led to the isolation of one original iridoid glycoside (1) along with six known iridoids (2–7), three lignans (8–10), two flavonoids (11–12), one coumarin (13), two anthraquinones (14–15), two benzoic acids (16–17) and three triterpenoids (18–20). These results are the first chemical data on non-volatile constituents of this genus. The c ...
DOI:
10.1016/j.bse.2016.11.010

45. Chiral separation and chemical profile of Dengzhan Shengmai by integrating comprehensive with multiple heart-cutting two-dimensional liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Author:
Ning Sheng; Hao Zheng; Yao Xiao; Zhe Wang; Menglin Li; Jinlan Zhang
Source:
Journal of chromatography 2017 v.1517 pp. 97-107
ISSN:
0021-9673
Subject:
Oriental traditional medicine; chemical composition; comprehensive two-dimensional liquid chromatography; cutting; flavonoids; herbs; high performance liquid chromatography; isomers; lignans; mass spectrometry; saponins
Abstract:
... Chemical profile for Chinese medicine formulas composed of several herbs is always a challenge due to a big array of small molecules with high chemical diversity so much as isomers. The present paper develops a feasible strategy to characterize and identify complex chemical constituents of a four-herb traditional Chinese medicine formula, Denzhan Shenmai (DZSM) by integrating comprehensive two-dim ...
DOI:
10.1016/j.chroma.2017.08.037

46. Comparative analysis of the in-vitro antioxidant activity and bioactive compounds of flaxseed in China according to variety and geographical origin

Author:
Qianchun Deng; Xiao Yu; Fangli Ma; Jiqu Xu; Fenghong Huang; Qingde Huang; Feng Sheng
Source:
International journal of food properties 2017 v.20 no.sup3 pp. S2708
ISSN:
1094-2912
Subject:
2,2-diphenyl-1-picrylhydrazyl; alpha-linolenic acid; antioxidant activity; antioxidants; bioactive compounds; chemometrics; glucosides; lignans; linseed; p-coumaric acid; phytosterols; principal component analysis; provenance; syringic acid; China
Abstract:
... The present study aimed to use a chemometric study to compare the in-vitro antioxidant activities and bioactive compounds of flaxseed based on the variety and geographical origins, and further explore the specific components constructed the endogenous antioxidant system of flaxseed in China. The differential contents of α-linolenic acid (35.83–58.91%), lignans (11.37–33.31 mg/g), total phenolic ac ...
DOI:
10.1080/10942912.2017.1402029

47. Composition and Statistical Analysis of Biophenols in Apulian Italian EVOOs

Author:
Andrea Ragusa; Carla Centonze; Maria Elena Grasso; Maria Francesca Latronico; Pier Francesco Mastrangelo; Francesco Paolo Fanizzi; Michele Maffia
Source:
Foods 2017 v.6 no.10 pp. -
ISSN:
2304-8158
Subject:
Mediterranean diet; Olea europaea; alpha-tocopherol; antioxidant activity; cultivars; dietary supplements; discriminant analysis; extra-virgin olive oil; harvesting; high performance liquid chromatography; least squares; lignans; luteolin; metabolites; milling; principal component analysis; Italy
Abstract:
... Extra-virgin olive oil (EVOO) is among the basic constituents of the Mediterranean diet. Its nutraceutical properties are due mainly, but not only, to a plethora of molecules with antioxidant activity known as biophenols. In this article, several biophenols were measured in EVOOs from South Apulia, Italy. Hydroxytyrosol, tyrosol and their conjugated structures to elenolic acid in different forms w ...
DOI:
10.3390/foods6100090
PubMed:
29057813
PubMed Central:
PMC5664029

48. Comprehensive profiling and characterization of chemical constituents of rhizome of Anemarrhena asphodeloides Bge.

Author:
De Ji; Zi-yan Huang; Cheng-hao Fei; Wei-wei Xue; Tu-lin Lu
Source:
Journal of chromatography 2017 v.1060 pp. 355-366
ISSN:
1570-0232
Subject:
Anemarrhena asphodeloides; chemical composition; cyclic peptides; fatty acids; flavones; herbal medicines; ions; lignans; mass spectrometry; metabolites; quality control; rhizomes; steroid saponins; ultra-performance liquid chromatography; xanthones; China
Abstract:
... The rhizome of Anemarrhena asphodeloides Bge. is commonly used as an herbal medicine in China. In this study, ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) was used, in both negative and positive ion modes, to comprehensively analyze the chemical constituents of A. asphodeloides. From the intact precursor ions, MS/MS fragmenta ...
DOI:
10.1016/j.jchromb.2017.06.032

49. Configuration and stability of naturally occurring all-cis-tetrahydrofuran lignans from Piper solmsianum

Author:
Clécio S. Ramos; Harrald V. Linnert; Marcilio M. de Moraes; João H. do Amaral; Lydia F. Yamaguchi; Massuo J. Kato
Source:
RSC advances 2017 v.7 no.74 pp. 46932-46937
ISSN:
2046-2069
Subject:
Piper; density functional theory; hydrogen bonding; isomers; leaves; lignans; nuclear magnetic resonance spectroscopy; spectral analysis; tetrahydrofuran
Abstract:
... The study of variability of the tetrahydrofuran lignan (−)-grandisin in leaves of Piper solmsianum (Piperaceae) revealed two unknown compounds, that were isolated and determined to be the all-cis tetrahydrofuran lignans 1a [rel-(7R,8S,7′S,8′R)-3,4,5,3′,4′,5′-hexamethoxy-7,7′-epoxylignan] and 1b [rel-(7R,8S,7′S,8R′)-3′,4′-methylenedioxy-3,4,5,5′-tetramethoxy-7,7′-epoxylignan]. Their structures were ...
DOI:
10.1039/c7ra09262h

50. The Contents of Lignans in Sesame Seeds and Commercial Sesame Oils of China

Author:
Long‐Kai Shi; Rui‐Jie Liu; Qing‐Zhe Jin; Xing‐Guo Wang
Source:
The journal of the American Oil Chemists' Society 2017 v.94 no.8 pp. 1035-1044
ISSN:
0003-021X
Subject:
high performance liquid chromatography; lignans; seeds; sesame oil; sesame seed; China
Abstract:
... In this study, the concentrations of three lignans in 100 sesame seeds and 56 sesame oils were determined using a newly developed method based on high‐performance liquid chromatography coupled with a UV/Vis detector. Total lignan contents in sesame seed and oil samples ranged from 2.52 to 12.76 and 3.38 to 11.53 mg/g, respectively. Black sesame seeds showed higher sesamin content (range 1.98–9.41 ...
DOI:
10.1007/s11746-017-3018-7