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... Chronobiological disruptions, including shift work, have been linked to a number of disorders such as fatigue and diabetes. Additionally, there is evidence to support that exercise cannot only counteract fatigue and the onset of diabetes, but also alleviate the other negative symptoms associated with shift work. Therefore, the present study investigated the effects of wheel running and monthly 6-h ...
... The molecular mechanisms of muscle weakness and sarcopenia in postmenopausal women are largely unknown. To determine the effect of a new estrogen receptor, GPR30, in the maintenance of exercise capacity and skeletal muscle function in females, the selective GPR30 agonist, G1 (100 μg/kg/day), or vehicle (V, soybean oil) was administered subcutaneously daily (n = 7 per group) to ovariectomized (OVX) ...
... BACKGROUND: The purple mangosteen (Garcinia mangostana), known as the "queen of fruit," is widely consumed and unique not only because of its outstanding appearance and flavor but also its remarkable and diverse pharmacological effects. The aim of the present study is to evaluate the effect of acute mangosteen supplementation on physical fatigue during exercise. METHODS: A randomized, double-blind ...
Elfego Galvan; Dillon K. Walker; Sunday Y. Simbo; Ryan Dalton; Kyle Levers; Abigail O’Connor; Chelsea Goodenough; Nicholas D. Barringer; Mike Greenwood; Christopher Rasmussen; Stephen B. Smith; Steven E. Riechman; James D. Fluckey; Peter S. Murano; Conrad P. Earnest; Richard B. Kreider
... BACKGROUND: Creatine monohydrate (CrM) and nitrate are popular supplements for improving exercise performance; yet have not been investigated in combination. We performed two studies to determine the safety and exercise performance-characteristics of creatine nitrate (CrN) supplementation. METHODS: Study 1 participants (N = 13) ingested 1.5 g CrN (CrN-Low), 3 g CrN (CrN-High), 5 g CrM or a placebo ...
... Acute exercise-induced improvements in cognitive function are accompanied by increased (cerebral) blood flow and increased brain-derived neurotrophic factor (BDNF) levels. Acute cocoa flavanol (CF) intake may improve cognitive function, cerebral blood flow (in humans), and BNDF levels (in animals). This study investigated (i) the effect of CF intake in combination with exercise on cognitive functi ...
... Dopamine/norepinephrine (DA/NE) reuptake inhibitors have been used to manipulate the central mechanisms affecting arousal and motivation during exercise. Eight healthy, physically active males performed 30min fixed-intensity cycling at 50% Wmax followed by 30min of self paced time trial (TT) with each section interspersed with a 30 s maximal sprint at 9, 19 and 29min. The DA/NE re-uptake inhibitor ...
acute effects; analysis of variance; central nervous system diseases; cognition; cost effectiveness; dose response; exercise; experimental design; people; sclerosis; walking
Abstract:
... Exercise training represents a promising approach for managing cognitive impairment in persons with multiple sclerosis (MS). There is preliminary evidence that treadmill walking might be the modality of exercise that exerts the greatest beneficial effects on inhibitory control in fully-ambulatory persons with MS. However, the dose-dependent effects of varying intensities of treadmill walking exerc ...
Valdir de Aquino-Lemos; Ronaldo Vagner T. Santos; Hanna Karen Moreira Antunes; Fabio S. Lira; Irene G. Luz Bittar; Aline V. Caris; Sergio Tufik; Marco Tulio de Mello
... This study aimed to assess the effect of two sessions of acute physical exercise at 50% VO2peak performed under hypoxia (equivalent to an altitude of 4500m for 28h) on sleep, mood and reaction time. Forty healthy men were randomized into 4 groups: Normoxia (NG) (n=10); Hypoxia (HG) (n=10); Exercise under Normoxia (ENG) (n=10); and Exercise under Hypoxia (EHG) (n=10). All mood and reaction time ass ...
Mexicans; cognition; diet; diet therapy; exercise; obesity; overeating; problem solving; questionnaires; social support; weight control; women
Abstract:
... Lack of follow up treatment for weight control and maintenance by Mexican women represents a serious problem for the health system. This study assess an intervention to increase adherence in women with overweight and obesity through motivational interviewing combined with brief therapy centered in problem solving cognitive behavioral. A quasi-experimental study was designed, with pre and post trea ...
... Early life stressful events have detrimental effects on the brain and behavior, which are associated with the development of depression. Immune-inflammatory responses have been reported to contribute in the pathophysiology of depression. Many studies have reported on the beneficial effects of exercise against stress. However, underlying mechanisms through which exercise exerts its effects were poo ...
air pollutants; air pollution; air quality; cities; exercise; particulates; traffic; California
Abstract:
... CicLAvia in Los Angeles, CA is the open streets program that closes streets to motorized vehicles and invites people to walk, run, play or ride their bicycles on these streets, allowing them to experience the city in a new way and get exercise at the same time. Since the events reduce the motorized traffic flow, which is a significant source of air pollution, on the streets, it is reasonable to hy ...
... The adrenal and gonadal stress steroids [i.e., cortisol, testosterone and dehydroepiandrosterone (DHEA)] have gathered considerable attention in the last few decades due to their very broad physiological and psychological actions. Their diurnal patterns have become a particular focus following new data implicating altered diurnal hormone patterns in various endocrine, behavioral and cardiovascular ...
... Several studies have generated numerous terms in the field of exercise training prescription and performance assessment that often do not match the information previously demonstrated by many other works, generating much debate and resulting in an immense pool of scientific results. Several protocols in exercise training prescription and performance assessment have been proposed for these purposes ...
... Panax ginseng C. A. Meyer (ginseng) is an edible and medicinal Chinese herb, which is often used in Asian countries for physical fitness. Ginseng is reported to have a wide range of biological activity and pharmaceutical properties. There were more studies on ginsenosides and polysaccharides, but fewer studies on ginseng oligopeptides (GOP), which are small molecule oligopeptides isolated from gin ...
Panax; adiponectin; antioxidant activity; antioxidants; body mass index; exercise; fatty liver; liver function; necrosis; neoplasms; overweight; placebos; research
Abstract:
... Korean Red Ginseng (KRG) is a well-known natural product with anticarcinogenic and antioxidant effects. We evaluated the antifatigue effect of KRG in patients with nonalcoholic fatty liver disease (NAFLD).Eighty patients with NAFLD were prospectively randomized to receive 3 wk of KRG or placebo in addition to counseling on healthy eating and regular exercise. Liver function test, proinflammatory c ...
... Actinidia arguta (Siebold et Zucc.) Planch. ex. Miq. is one of the most recently domesticated fruit species with increasing commercial production worldwide. It is a well-known traditional Chinese medicine and is used to reduce blood glucose and treat atopic dermatitis. In addition, it possesses antioxidant, anticancer, and antiallergic properties. In this study, we investigated the physical antifa ...
... The present study examined the association of anxiety and impulsivity with premature muzzle grayness among young dogs. A sample of 400 dogs, ages 1–4 years was obtained at dog parks, shows, veterinary clinics, and other venues. Each dog was photographed and the degree of muzzle grayness was rated on an ordinal scale ranging from “no gray” to “full gray.” White or pale colored dogs were dropped fro ...
... Discarded electrical and electronic equipment is a growing waste stream becoming more problematic in its management. Unsafe disposal contributes to environmental pollution and threatens human health as well as wasting secondary resources. The recovery of valuable metals from electronic waste can be achieved by bioleaching, a biologically mediated natural chemical process. The bioleaching process m ...
... The aim was to identify benefits of compression garments used for recovery of exercised-induced muscle damage.Computer-based literature research was performed in September 2015 using four online databases: Medline (PubMed), Cochrane, WOS (Web Of Science) and Scopus. The analysis of risk of bias was completed in accordance with the Cochrane Collaboration Guidelines. Mean differences and 95% confide ...
Equus hemionus hemionus; Thoroughbred; anesthesia; blood; blood gases; blood pH; exercise; global positioning systems; horses; lactic acid; normal values
Abstract:
... Research and conservation of wide-ranging wild equids in most cases necessitate capture and handling of individuals. For free-roaming Mongolian khulan (Equus hemionus hemionus), also known as the khulan, capture involves a strenuous, high-speed chase, and physiologic responses have yet to be elucidated. We analyzed sequential arterial blood gas (ABG) samples as a proxy for respiratory and metaboli ...
Holger Behrsing; Hans Raabe; Joseph Manuppello; Betsy Bombick; Rodger Curren; Kristie Sullivan; Sanjay Sethi; Richard Phipps; Yohannes Tesfaigzi; Sherwin Yan; Carl D'Ruiz; Robert Tarran; Samuel Constant; Gary Phillips; Marianna Gaça; Patrick Hayden; Xuefei Cao; Carole Mathis; Julia Hoeng; Armin Braun; Erin Hill
Food and Drug Administration; exercise; hyperplasia; inflammation; laboratories; manufacturing; mortality; mucus; oxidative stress; respiratory tract diseases; stakeholders; tobacco; toxicology
Abstract:
... The Family Smoking Prevention and Tobacco Control Act of 2009 established the Food and Drug Administration Center for Tobacco Products (FDA-CTP), and gave it regulatory authority over the marketing, manufacture and distribution of tobacco products, including those termed ‘modified risk’. On 8–10 December 2014, IIVS organised a workshop conference, entitled Assessment of In Vitro COPD Models for To ...
Marieke G. Schooneman; Antonella Napolitano; Sander M. Houten; Graeme K. Ambler; Peter R. Murgatroyd; Sam R. Miller; Carla E.M. Hollak; Chong Y. Tan; Samuel Virtue; Antonio Vidal-Puig; Derek J. Nunez; Maarten R. Soeters
Food and Agriculture Organization; beta oxidation; diet; drug therapy; energy expenditure; exercise; fasting; free fatty acids; glucose; humans; insulin resistance; noninsulin-dependent diabetes mellitus; weight loss
Abstract:
... Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans. Moreover plasma acylcarnitines have been associated with clinical parameters related to glucose metabolism, such as fasting glucose levels and HbA1c. We hypothesized that plasma acylcarnitine ...
... Serum levels of adropin, which enhances endothelial cell release of nitric oxide (NO), are lower in obese patients. Although habitual aerobic exercise reduces arterial stiffness and adiposity, the relationship between these effects and circulating levels of adropin remains unclear. The purpose of this study was to determine if serum adropin level is associated with the effects of aerobic exercise ...
... The South Asian population suffers from a high prevalence of type 2 diabetes and cardiovascular disease (CVD). A unique obesity phenotype of elevated visceral adipose tissue (VAT) is associated with CVD risk among South Asians. Exercise-induced reduction in VAT and body fat is an effective mechanism to improve cardiometabolic risk factors but this has not been shown in South Asians. Whether exerci ...
... OBJECTIVE: Our aim of this study was to investigate the association between fish consumption and depressive symptoms in senior ethnic Chinese residents of Singapore. DESIGN: A population-based crosssectional study. SETTING: The Singapore Longitudinal Aging Studies (SLAS). PARTICIPANT: The study consisted of 2,034 participants from the Singapore Longitudinal Aging Studies (SLAS) project who were at ...
Thoroughbred; exercise; mucus; neutrophils; racehorses; racing performance; risk factors
Abstract:
... OBJECTIVES: To determine the variation of tracheal mucus scores, tracheal blood scores and transendoscopic tracheal wash (TW) cytology in a population of Thoroughbred (TB) racehorses and assess their association with racing performance. METHODS: A total of 220 endoscopic examinations were performed and TWs obtained from 155 TB racehorses. Samples were collected 60–120 min following gallop work. Tr ...
Thoroughbred; ambient temperature; blood; climatic factors; cross-sectional studies; exercise; hemorrhage; racehorses; regression analysis; risk factors; tongue; veterinarians; Western Australia
Abstract:
... REASONS FOR PERFORMING STUDY: Ambient temperature has been identified as a risk factor for exercise‐induced pulmonary haemorrhage (EIPH) in racing Thoroughbreds. This warranted a more expansive investigation of climatic conditions on the incidence and severity of EIPH. The impact of other variables such as the type of bit used, tongue ties and nonstandard shoes has not been reported and also warra ...
Pam R. Taub; Israel Ramirez-Sanchez; Minal Patel; Erin Higginbotham; Aldo Moreno-Ulloa; Luis Miguel Román-Pintos; Paul Phillips; Guy Perkins; Guillermo Ceballos; Francisco Villarreal
biomarkers; biopsy; blood sampling; chocolate; citrate (si)-synthase; clinical trials; enzyme activity; exercise; exercise test; glutathione; heart failure; high density lipoprotein; mitochondria; oxidative stress; patients; placebos; protein content; skeletal muscle; triacylglycerols
Abstract:
... In heart failure patients the consumption of (−)-epicatechin ((−)-Epi)-rich cocoa can restore skeletal muscle (SkM) mitochondrial structure and decrease biomarkers of oxidative stress. However, nothing is known about its effects on exercise capacity and underlying mechanisms in normal, sedentary subjects. Twenty normal, sedentary subjects (∼50 years old) were randomized to placebo or dark chocolat ...
... The prevalence of type 2 diabetes (T2D) is predicted to reach unprecedented levels in the next few decades. In addition to excess body weight, there may be other overlapping dietary drivers of impaired glucose homeostasis that are associated with an obesogenic diet, such as regular exposure to postprandial spikes in blood glucose arising from diets dominated by highly refined starches and added su ...
Asif Nakhuda; Andrea R Josse; Valentina Gburcik; Hannah Crossland; Frederic Raymond; Sylviane Metairon; Liam Good; Philip J Atherton; Stuart M Phillips; James A Timmons
DNA microarrays; RNA; adipocytes; binding proteins; biomarkers; body composition; energy balance; exercise; exons; gene expression; liver; low calorie diet; mice; overweight; phenotype; weight loss; white adipose tissue; women
Abstract:
... Background: A hypothesis exists whereby an exercise- or dietary-induced negative energy balance reduces human subcutaneous white adipose tissue (scWAT) mass through the formation of brown-like adipocyte (brite) cells. However, the validity of biomarkers of brite formation has not been robustly evaluated in humans, and clinical data that link brite formation and weight loss are sparse. Objectives: ...
algorithms; biopharmaceuticals; circular dichroism spectroscopy; exercise; insulin; light scattering; nuclear magnetic resonance spectroscopy; oligomerization; pH; protein structure; temperature; zinc
Abstract:
... Although protein structure has been studied for many decades it remains the case that we cannot state with confidence whether two samples have the same molecular structure, particularly in solution. The increasing number of biosimilar biopharmaceutical drugs that are being tested means this is not an academic exercise. In this work we consider how four well-established techniques: dynamic light sc ...
... BACKGROUND: The decline in cognitive performance has been shown after fatiguing exercise. Branched-chain amino acids (BCAA) have been suggested to alleviate exercise-induced central fatigue. Arginine and citrulline could remove the excess NH₃ accumulation accompanied with BCAA supplementation by increasing nitric oxide biosynthesis and/or urea cycle. The purpose of this study is to investigate the ...
... Caffeine blunts RPE estimations but effects on selected cycling cadence are unclear.This study examined influence of caffeine on cycling cadence with intensities prescribed at RPE 4 and 7 (OMNI Scale).College-aged (20.5±2.0y) male and female volunteers (n=15) (VO2 peak=40.3±4.0,) completed a maximal cycling test followed by trials where they adjusted cadence (CAD) (clamped resistances) to produce ...
animal behavior; dogs; exercise; females; humans; pet ownership; posture
Abstract:
... In the context of dog training it would be of utmost importance to understand the mechanisms that control how attention to humans is allocated by dogs, and how this can be modified by training. This study aimed at characterising the patterns of attention paid to their handler by dogs with different training level, while performing typical obedience tasks in conditions of increasing difficulty. The ...
... Metabolic diseases have got global health issues. Physical exercise as well as diet therapy is a potent strategy for fighting against the diseases. However, it is often difficult to continue to keep exercise regularly enough to take sufficient effect. Thus, good substitutes for the therapeutic exercise would be greatly beneficial. Recent studies have suggested that 5′AMP-activated protein kinase ( ...
... Critical power (CP) conceptually represents the highest power output (PO) at physiological steady-state. In cycling exercise, CP is traditionally derived from the hyperbolic relationship of ∼5 time-to-exhaustion trials (TTE) (CPHYP). Recently, a 3-min all-out test (CP₃MIN) has been proposed for estimation of CP as well the maximal lactate steady-state (MLSS). The aim of this study was to compare t ...
Mark S. Tremblay; Valerie Carson; Jean-Philippe Chaput; Sarah Connor Gorber; Thy Dinh; Mary Duggan; Guy Faulkner; Casey E. Gray; Reut Gruber; Katherine Janson; Ian Janssen; Peter T. Katzmarzyk; Michelle E. Kho; Amy E. Latimer-Cheung; Claire LeBlanc; Anthony D. Okely; Timothy Olds; Russell R. Pate; Andrea Phillips; Veronica J. Poitras; Sophie Rodenburg; Margaret Sampson; Travis J. Saunders; James A. Stone; Gareth Stratton; Shelly K. Weiss; Lori Zehr
... Leaders from the Canadian Society for Exercise Physiology convened representatives of national organizations, content experts, methodologists, stakeholders, and end-users who followed rigorous and transparent guideline development procedures to create the Canadian 24-Hour Movement Guidelines for Children and Youth: An Integration of Physical Activity, Sedentary Behaviour, and Sleep. These novel gu ...
... The aim was to investigate the influence of a carbohydrate (CHO) mouth rinse on the vastus lateralis (VL) and rectus femoris (RF) electromyographic activity (EMG) and time to exhaustion (TE) during moderate (MIE) and high-intensity cycling exercise (HIE). Thirteen participants cycled at 80% of their respiratory compensation point and at 110% of their peak power output to the point of exhaustion. B ...
... There is good evidence that mouth rinsing with carbohydrate (CHO) solutions can enhance endurance performance (≥30 min). The impact of a CHO mouth rinse on sprint performance has been less consistent, suggesting that CHO may confer benefits in conditions of ‘metabolic strain’. To test this hypothesis, the current study examined the impact of late-exercise mouth rinsing on sprint performance. Secon ...
... BACKGROUND: The effect of mouth rinsing with a carbohydrate (CHO) solution on exercise performance is inconclusive with no benefits observed in the fed state. This study examined the effect of CHO mouth rinse or CHO ingestion on performance in 9 moderately trained male cyclists. METHODS: Four trials were undertaken, separated by 7 days, in a randomized, counterbalanced design. Each trial included ...
... BACKGROUND: Carbohydrate (CHO) supplementation during prolonged exercise is widely acknowledged to blunt in vitro immunoendocrine responses, but no study has investigated in vivo immunity. PURPOSE: To determine the effect of CHO supplementation during prolonged exercise on in vivo immune induction using experimental contact hypersensitivity with the novel antigen diphenylcyclopropenone (DPCP). MET ...
... The prevalence of congenital heart disease is higher in camelids than in other domestic species and complex defects, often involving the great vessels, are more frequently encountered in llamas and alpacas than in other species. Some of these complex defects can be difficult to accurately characterize via echocardiography, the most commonly used diagnostic imaging technique to evaluate the heart i ...
case studies; data collection; education; exercise; food safety; food security; gardens; gender; households; logit analysis; motivation; organic production; parks; recreation; social cohesion; Portugal
Abstract:
... Demand for urban allotment plots has recently increased in Portugal but little is known about the characteristics and motivations of the demanding population, and if and how its characteristics affect its motivations.In this article, we use the Municipal Network of Urban Allotment Gardens (MNUAG)11MNUAG − Municipal Network of Urban Allotment Gardens. launched by the Portuguese municipality of Vila ...
... Combined isometric exercise or metaboreflex activation (post-exercise muscle ischaemia (PEMI)) and cold pressor test (CPT) increase cardiac afterload, which may lead to adverse cardiovascular events. l-Citrulline supplementation (l-CIT) reduces systemic arterial stiffness (brachial-ankle pulse wave velocity (baPWV)) at rest and aortic haemodynamic responses to CPT. The aim of this study was to det ...
... A previous report suggests a substantial incidence of exertional rhabdomyolysis (ER) in Arabian horses performing endurance racing. This study compared formalin histopathology and clinical and metabolic responses to a standardised field exercise test (SET) between Arabians with and without ER. Arabian horses with (n = 10; age 15.4 ± 5.6 years) and without (n = 9; 12.9 ± 6.1 years) prior ER were st ...
... It has been suggested that breakfast omission, as opposed to breakfast consumption, has the detrimental effects on cognitive function. However, the effects of acute exercise following breakfast omission on cognitive function are poorly understood, particularly during exercise. The purpose of this study was to examine the interactive effects of breakfast and exercise on cognitive function. Ten part ...
... After menopause the incidence of cardiovascular diseases increases in women. A decrease in nitric oxide (NO) bioavailability has been pointed out to play a major role in this phenomenon. Since it is believed that l-arginine administration could improve NO bioavailability, the aim of this study was to examine the effects of acute l-arginine administration associated with aerobic exercise on blood p ...
analysis of variance; body fat; exercise; lifestyle; public research; university research
Abstract:
... Incentivized exercise program interventions have recently led to mixed findings with regard to increasing physical activity, attendance, and improving healthy lifestyles. However, in this area limited research exists on implementing a combined negative reinforcement strategy, using a “buy-in” and positive reinforcement system.To determine the effect of comparing a non-incentivized reward system wi ...
... Consuming carbohydrate- and antioxidant-rich fruits during exercise as a means of supporting and enhancing both performance and health is of interest to endurance athletes. Watermelon (WM) contains carbohydrate, lycopene, l-citrulline, and l-arginine. WM may support exercise performance, augment antioxidant capacity, and act as a countermeasure to exercise-induced inflammation and innate immune ch ...
... Beetroot is a vegetable rich in nitrate (NO ₃ ⁻), antioxidants and phenolic compounds that are related to improvements in cardiovascular function and exercise performance. However, it is unknown if convenient forms of beetroot administration provide different amounts of these nutrients. The total antioxidant potential (TAP), total phenolic (TPC), sugar, organic acid, and NO ₃ ⁻ contents of beetroo ...