Publication Year: 2015 / Subject: antibiotics

1. (Lipo)polysaccharide interactions of antimicrobial peptides

Author:: Artur Schmidtchen; Martin Malmsten
Source:: Journal of colloid and interface science 2015 v.449 pp. 136-142
ISSN:: 0021-9797
Subject:: antibiotics; antimicrobial peptides; polysaccharides
Abstract:: ... Due to rapidly increasing resistance development against conventional antibiotics, as well as problems associated with diseases either triggered or deteriorated by infection, antimicrobial and anti-inflammatory peptides have attracted considerable interest during the last few years. While there is an emerging understanding of the direct antimicrobial function of such peptides through bacterial mem ...
DOI:: 10.1016/j.jcis.2014.11.024
: https://doi.org/10.1016/j.jcis.2014.11.024

2. 272 cases of rattlesnake envenomation in dogs: Demographics and treatment including safety of F(ab′)2 antivenom use in 236 patients

Author:: Amanda J. Witsil; Raegan J. Wells; Craig Woods; Sangeeta Rao
Source:: Toxicon 2015 v.105 pp. 19-26
ISSN:: 0041-0101
Subject:: antibiotics; antivenoms; demographic statistics; dogs; glucocorticoids; hypersensitivity; immunoglobulin A; morbidity; mortality; patients; snake bites; vaccination; Arizona
Abstract:: ... Medical records of 272 rattlesnake envenomations of canines from 5 veterinary emergency centers in Maricopa County, Arizona between 2010 and 2012 were investigated. The objectives were to examine the patient demographics, severity of clinical signs, and treatment modalities employed, in order to discuss the outcomes of certain therapies including glucocorticoid use, antibiotic use, rattlesnake vac ...
DOI:: 10.1016/j.toxicon.2015.08.028
: https://doi.org/10.1016/j.toxicon.2015.08.028

3. 29-Deoxymaklamicin, a new maklamicin analogue produced by a genetically engineered strain of Micromonospora sp. NBRC 110955

Author:: Ratama Daduang; Shigeru Kitani; Yuri Sudoh; Ivy Grace Umadhay Pait; Arinthip Thamchaipenet; Haruo Ikeda; Yasuhiro Igarashi; Takuya Nihira
Source:: Journal of bioscience and bioengineering 2015 v.120 no.6 pp. 608-613
ISSN:: 1389-1723
Subject:: Gram-positive bacteria; Micromonospora; Streptomyces avermitilis; anti-infective properties; antibiotics; biochemical pathways; biosynthesis; cytochrome P-450; gene deletion; genetically engineered microorganisms
Abstract:: ... Maklamicin is a spirotetronate-class antibiotic produced by Micromonospora sp. NBRC 110955, and a polyketide assembly line and a glycerate utilization system are involved in its biosynthesis. One tailoring step in the biosynthesis is predicted to be post-polyketide synthase (PKS) modification, which seems to be catalysed by putative cytochrome P450 monooxygenases, MakC2 and/or MakC3. In this study ...
DOI:: 10.1016/j.jbiosc.2015.04.004
: https://doi.org/10.1016/j.jbiosc.2015.04.004

4. A 3’ external transcribed spacer in a tRNA transcript acts as a sponge for small RNAs to prevent transcriptional noise

Author:: David Lalaouna; Marie-Claude Carrier; Szabolcs Semsey; Jean-Simon Brouard; Jing Wang; Joseph T. Wade; Eric Massé
Source:: Molecular cell 2015 pp. -
ISSN:: 1097-2765
Subject:: RNA precursors; antibiotics; byproducts; internal transcribed spacers; transcription (genetics); transfer RNA; tricarboxylic acid cycle
Abstract:: ... During ribosomal and transfer RNA maturation, external transcribed spacer (ETS) and internal transcribed spacer (ITS) sequences are excised and, as non-functional by-products, are rapidly degraded. However, we report that the 3’ETS of the glyW-cysT-leuZ polycistronic tRNA precursor is highly and specifically enriched by co-purification with at least two different small regulatory RNAs (sRNAs), Ryh ...
DOI:: 10.1016/j.molcel.2015.03.013
: https://doi.org/10.1016/j.molcel.2015.03.013

5. 6-Tosyl-4,5,6,7-Tetrahydrothieno[2,3-c]Pyridine-3-Carboxamide Analogues: Synthesis, Characterization, MO Calculation, and Antibacterial Activity

Author:: Hiren Doshi; Sampark Thakkar; Prashant Khirsariya; Mukund Chandra Thakur; Arabinda Ray
Source:: Applied biochemistry and biotechnology 2015 v.175 no.3 pp. 1700-1709
ISSN:: 0273-2289
Subject:: Bacillus subtilis; Escherichia coli; Staphylococcus aureus; antibacterial properties; antibiotics; biotechnology; ciprofloxacin; nuclear magnetic resonance spectroscopy
Abstract:: ... A series of 6-tosyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide analogues are synthesized by conventional techniques and characterized by elemental analysis, IR, MS,¹H, and¹³C NMR. These are tested for their antibacterial activity against Bacillus subtilis (abbreviated as BS), Staphylococcus aureus (abbreviated as SA), and Escherichia coli (abbreviated as EC). The synthesized compounds a ...
DOI:: 10.1007/s12010-014-1399-8
: https://doi.org/10.1007/s12010-014-1399-8

6. AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?

Author:: Zhongke Sun; Verena Grimm; Christian U. Riedel
Source:: Trends in microbiology 2015 v.23 no.6 pp. 327-328
ISSN:: 0966-842X
Subject:: antibiotics; dysbiosis; infectious diseases; intestinal microorganisms; pathogens
Abstract:: ... The downside of antibiotic treatment of infectious diseases is a disturbed intestinal microbiota leading to reduced resistance against pathogen colonization. Work by Thompson et al. now suggests that antibiotic-induced intestinal dysbiosis can partially be counterbalanced by artificially increasing the levels of autoinducer-2 (AI-2), a well-known bacterial communication molecule. ...
DOI:: 10.1016/j.tim.2015.04.002
: https://doi.org/10.1016/j.tim.2015.04.002

7. AKTIVITAS ANTIBAKTERI EKSTRAK BUAH ADAS (Foeniculum vulgare, Mill) PADA Vibrio harveyi DAN Vibrio alginolyticus Antibacterial Activity of Fennel (Foeniculum vulgare Mill) Extract on Vibrio alginolyticus and Vibrio harveyi

Author:: Budianto; Arief Prajitno; Ating Yuniarti
Source:: Agritech 2015 v.35 no.03 pp. 266-272
ISSN:: 2527-3825
Subject:: Foeniculum vulgare; Vibrio alginolyticus; Vibrio harveyi; air; antibacterial properties; antibiotics; disk diffusion antimicrobial test; fennel; fruits; minimum inhibitory concentration; vibriosis
Abstract:: ... Evaluation of natural products as a safe and effective antimicrobial agent is a scientific strategy to treat the drugresistant pathogens.Fennel(FoeniculumvulgareMill) is an herbal plant that has an active in gredient which is one of its benefit sasan antibacterial material. In thisstudy,water extract of fennel fruit determined the antibacterial activity against Vibrio harveyi and Vibrio alginolyti ...
DOI:: 10.22146/agritech.9336
: https://doi.org/10.22146/agritech.9336

8. Achieving energy goals at day 4 after admission in critically ill children; predictive for outcome?

Author:: C.T.I. de Betue; W.N. van Steenselen; J.M. Hulst; J.F. Olieman; M. Augustus; S.H. Mohd Din; S.C.A.T. Verbruggen; D. Tibboel; K.F.M. Joosten
Source:: Clinical nutrition 2015 v.34 no.1 pp. 115-122
ISSN:: 0261-5614
Subject:: antibiotics; children; energy intake; malnutrition; parenteral feeding; patients; protocols; resting energy expenditure
Abstract:: ... Adequate nutritional intake is essential during pediatric intensive care admission. We investigated whether achievement of energy intake goals at day 4 after admission and route of nutrition were associated with improved outcome.Observational study using prospectively acquired data. Patients receiving enteral and/or parenteral nutrition were included. The energy intake target range at day 4 after ...
DOI:: 10.1016/j.clnu.2014.01.019
: https://doi.org/10.1016/j.clnu.2014.01.019

9. Acid-activated biochar increased sulfamethazine retention in soils

Author:: Meththika Vithanage; Anushka Upamali Rajapaksha; Ming Zhang; Sören Thiele-Bruhn; Sang Soo Lee; Yong Sik Ok
Source:: Environmental science and pollution research international 2015 v.22 no.3 pp. 2175-2186
ISSN:: 0944-1344
Subject:: adsorbents; antibiotics; biochar; invasive species; loamy sand soils; models; sand; sandy loam soils; soil amendments; soil pH; sorption
Abstract:: ... Sulfamethazine (SMZ) is an ionizable and highly mobile antibiotic which is frequently found in soil and water environments. We investigated the sorption of SMZ onto soils amended with biochars (BCs) at varying pH and contact time. Invasive plants were pyrolyzed at 700 °C and were further activated with 30 % sulfuric (SBBC) and oxalic (OBBC) acids. The sorption rate of SMZ onto SBBC and OBBC was pr ...
DOI:: 10.1007/s11356-014-3434-2
: https://doi.org/10.1007/s11356-014-3434-2

10. Acorus calamus rhizome extract mediated biosynthesis of silver nanoparticles and their bactericidal activity against human pathogens

Author:: Chinnappan Sudhakar; Kandasamy Selvam; Muthusamy Govarthanan; Balakrishnan Senthilkumar; Arumugam Sengottaiyan; Murugesan Stalin; Thangasamy Selvankumar
Source:: Journal of Genetic Engineering and Biotechnology (Print) 2015 v.13 no.2 pp. 93-99
ISSN:: 1687-157X
Subject:: Acorus calamus; Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus aureus; X-ray diffraction; animal pathogens; antibacterial properties; antibiotics; biosynthesis; dose response; energy; energy-dispersive X-ray analysis; medicine; microbial growth; nanosilver; response surface methodology; rhizomes; scanning electron microscopy; secondary metabolites; silver; silver nitrate; surface plasmon resonance; temperature; ultraviolet-visible spectroscopy
Abstract:: ... Silver nanoparticle (AgNP) synthesis and characterization is an area of vast interest due to their broader application in the fields of science and technology and medicine. Plants are an attractive source for AgNP synthesis because of its ability to produce a wide range of secondary metabolites with strong reducing potentials. Thus, the present study describes the synthesis of AgNPs using aqueous ...
DOI:: 10.1016/j.jgeb.2015.10.003
PubMed:: 30647572
PubMed Central:: PMC6299866
: https://doi.org/10.1016/j.jgeb.2015.10.003

11. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity

Author:: Jessica M. A. Blair; Vassiliy N. Bavro; Vito Ricci; Niraj Modi; Pierpaolo Cacciotto; Ulrich Kleinekathӧfer; Paolo Ruggerone; Attilio V. Vargiu; Alison J. Baylay; Helen E. Smith; Yvonne Brandon; David Galloway; Laura J. V. Piddock
Source:: Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.11 pp. 3511-3516
ISSN:: 0027-8424
Subject:: Escherichia coli; Salmonella Typhimurium; amino acids; antibiotics; ciprofloxacin; drugs; genes; models; multiple drug resistance; mutation; patients; phenotype; sequence analysis; substrate specificity; therapeutics; transporters
Abstract:: ... The incidence of multidrug-resistant bacterial infections is increasing globally and the need to understand the underlying mechanisms is paramount to discover new therapeutics. The efflux pumps of Gram-negative bacteria have a broad substrate range and transport antibiotics out of the bacterium, conferring intrinsic multidrug resistance (MDR). The genomes of pre- and posttherapy MDR clinical isola ...
DOI:: 10.1073/pnas.1419939112
PubMed:: 25737552
PubMed Central:: PMC4371985
: https://doi.org/10.1073/pnas.1419939112

12. Actinobacterial Flora in Feces of Healthy Cottontail Rabbits (Sylvilagus auduboni)

Author:: Yu Zhang; Hongming Tan; Qingli Deng; Lixiang Cao
Source:: Probiotics and antimicrobial proteins 2015 v.7 no.1 pp. 9-13
ISSN:: 1867-1306
Subject:: Arthrobacter; Brachybacterium; Brevibacterium; DNA; DNA primers; Dietzia; Leucobacter; Microbacterium; Nocardioides; Promicromonospora; Streptomyces; Sylvilagus; antibiotics; bacteria; community structure; feces; flora; genes; intestinal microorganisms; polymerase chain reaction; rabbits; ribosomal RNA
Abstract:: ... Most known antibiotics from bacteria are produced by Actinobacteria. However, little is known about the community structure and diversity of fecal actinobacteria from rabbit feces. To investigate the actinobacterial community structure in rabbit feces, different actinobacterial-specific primer sets were used to amplify the overlap regions of 16S rRNA genes from the same DNA. At the genus level, 12 ...
DOI:: 10.1007/s12602-014-9179-x
: https://doi.org/10.1007/s12602-014-9179-x

13. Actinobaculum schaalii bacteremia: A report of two cases

Author:: Lemuel R. Non; Allison Nazinitsky; Mark D. Gonzalez; Carey-Ann D. Burnham; Rupa Patel
Source:: Anaerobe 2015 v.34 pp. 84-85
ISSN:: 1075-9964
Subject:: Actinobaculum schaalii; Gram-positive bacteria; antibiotics; bacteremia; cryosurgery; kidney neoplasms; patients; pyelonephritis
Abstract:: ... We report two cases of bacteremia with Actinobaculum schaalii, a rarely reported, anaerobic, Gram-positive bacterium. The first case was a patient with renal cancer who developed pyelonephritis after cryoablation, and the second was a patient who developed sepsis after a urogenital procedure. Bacteremia resolved after administration of empiric antibiotic therapy. ...
DOI:: 10.1016/j.anaerobe.2015.04.006
: https://doi.org/10.1016/j.anaerobe.2015.04.006

14. Activation of Peroxymonosulfate by Benzoquinone: A Novel Nonradical Oxidation Process

Author:: Zhou Yang; Jiang Jin; Gao Yuan; Ma Jun; Pang Su-Yan; Li Juan; Lu Xue-Ting; Yuan Li-Peng
Source:: Environmental Science & Technology 2015 v.49 no.21 pp. 12941-12950
ISSN:: 1520-5851
Subject:: antibiotics; benzoquinones; electron paramagnetic resonance spectroscopy; hydroxyl radicals; kinetics; liquid chromatography; models; oxidation; pH; singlet oxygen; sulfamethoxazole; sulfates
Abstract:: ... The reactions between peroxymonosulfate (PMS) and quinones were investigated for the first time in this work, where benzoquinone (BQ) was selected as a model quinone. It was demonstrated that BQ could efficiently activate PMS for the degradation of sulfamethoxazole (SMX; a frequently detected antibiotic in the environments), and the degradation rate increased with solution pH from 7 to 10. Interes ...
DOI:: 10.1021/acs.est.5b03595
: https://doi.org/10.1021/acs.est.5b03595

15. Activation of Toxin-Antitoxin System Toxins Suppresses Lethality Caused by the Loss of σᴱ in Escherichia coli

Author:: Yasushi Daimon; Shin-ichiro Narita; Yoshinori Akiyama
Source:: Journal of bacteriology 2015 v.197 no.14 pp. 2316-2324
ISSN:: 0021-9193
Subject:: Escherichia coli; Gram-negative bacteria; antibiotics; antitoxins; bacterial toxins; cell growth; culture media; gene overexpression; genes; messenger RNA; mutants; mutation; neutralization; prokaryotic cells; signal transduction; stress response; suppressor cells; temperature; toxicity
Abstract:: ... σ ᴱ, an alternative σ factor that governs a major signaling pathway in envelope stress responses in Gram-negative bacteria, is essential for growth of Escherichia coli not only under stressful conditions, such as elevated temperature, but also under normal laboratory conditions. A mutational inactivation of the hicB gene has been reported to suppress the lethality caused by the loss of σ ᴱ. hicB e ...
DOI:: 10.1128/JB.00079-15
PubMed:: 25917909
PubMed Central:: PMC4524175
: https://doi.org/10.1128/JB.00079-15

16. Activation of the σᴱ-Dependent Stress Pathway by Conjugative TraR May Anticipate Conjugational Stress

Author:: Elicia D. Grace; Saumya Gopalkrishnan; Mary E. Girard; Matthew D. Blankschien; Wilma Ross; Richard L. Gourse; Christophe Herman
Source:: Journal of bacteriology 2015 v.197 no.5 pp. 924-931
ISSN:: 0021-9193
Subject:: DNA-directed RNA polymerase; Escherichia coli; antibiotic resistance; antibiotics; bacteria; biosynthesis; evolution; fimbriae; horizontal gene transfer; pathogens; plasmids; protein folding; proteinases; signal transduction; stress response; virulence
Abstract:: ... Horizontal gene transfer by conjugation plays a major role in bacterial evolution, allowing the acquisition of new traits, such as virulence and resistance to antibacterial agents. With the increased antibiotic resistance in bacterial pathogens, a better understanding of how bacteria modulate conjugation under changing environments and the genetic factors involved is needed. Despite the evolutiona ...
DOI:: 10.1128/JB.02279-14
PubMed:: 25535270
PubMed Central:: PMC4325106
: https://doi.org/10.1128/JB.02279-14

17. The Acute Oral Toxicity of Commonly Used Pesticides in Iran, to Honeybees (Apis Mellifera Meda)

Author:: Farhang Rasuli; Javad Nazemi Rafie; Amin Sadeghi
Source:: Journal of apicultural science 2015 v.59 no.1 pp. 17-26
ISSN:: 2299-4831
Subject:: Apis mellifera; active ingredients; acute toxicity; antibiotics; copper oxychloride; crops; dietary exposure; fenpropathrin; fungicides; insect pollination; phosalone; pirimicarb; poisoning; propargite; worker honey bees; Iran
Abstract:: ... The honey bee is credited with approximately 85% of the pollinating activity necessary to supply about one-third of the world’s food supply. Well over 50 major crops depend on these insects for pollination. The crops produce more abundantly when honey bees are plentiful. Worker bees are the ones primarily affected by pesticides. Poisoning symptoms can vary depending on the developmental stage of t ...
DOI:: 10.1515/jas-2015-0007
: https://doi.org/10.1515/jas-2015-0007

18. Acute toxicological effects on the earthworm Eisenia fetida of 18 common pharmaceuticals in artificial soil

Author:: Mª. Rosa Pino; Jonatan Val; Ana Mª. Mainar; Estefanía Zuriaga; Cecilia Español; Elisa Langa
Source:: Science of the total environment 2015 v.518-519 pp. 225-237
ISSN:: 0048-9697
Subject:: Eisenia fetida; acute toxicity; adverse effects; antibiotics; beta-adrenergic antagonists; bioassays; biosolids; blood; chemical structure; diclofenac; earthworms; ecotoxicology; gemfibrozil; ibuprofen; long term effects; lovastatin; soil; wastewater
Abstract:: ... Following soil applications of recycled water and biosolids, pharmaceutical residues can eventually enter the terrestrial environment. In vitro and in vivo assays have largely focused on the acute ecotoxicity of these compounds in aquatic systems. However, studies on the ecotoxicological effects of pharmaceuticals in soil biota are especially scarce.The aim of this study was to investigate the acu ...
DOI:: 10.1016/j.scitotenv.2015.02.080
: https://doi.org/10.1016/j.scitotenv.2015.02.080

19. Adaptation to NaCl Reduces the Susceptibility of Enterococcus faecalis to Melaleuca alternifolia (Tea Tree) Oil

Author:: Ee Lin Lim; Katherine Ann Hammer
Source:: Current microbiology 2015 v.71 no.4 pp. 429-433
ISSN:: 0343-8651
Subject:: Enterococcus faecalis; Melaleuca alternifolia; antibiotics; cross immunity; culture media; minimum inhibitory concentration; sodium chloride; solutes; tea tree oil; viability
Abstract:: ... This study investigated the hypothesis that the salt adaptation response of Enterococcus faecalis alters susceptibility to tea tree oil (TTO). Six E. faecalis isolates were adapted to 6.5 % NaCl, and then exposed to TTO in phosphate-buffered saline (PBS). One isolate was also exposed to TTO in Brain Heart Infusion Broth (BHIB). The viability of salt-adapted and non-adapted control cells was determ ...
DOI:: 10.1007/s00284-015-0871-1
: https://doi.org/10.1007/s00284-015-0871-1

20. Adherence Reduction of Campylobacter jejuni and Campylobacter coli Strains to HEp-2 Cells by Mannan Oligosaccharides and a High-Molecular-Weight Component of Cranberry Extract

Author:: Alejandra Ramirez-Hernandez; John Rupnow; Robert W. Hutkins
Source:: Journal of food protection 2015 v.78 no.8 pp. 1496-1505
ISSN:: 0362-028X
Subject:: Campylobacter coli; Campylobacter jejuni subsp. jejuni; additive effect; antibiotics; bacteria; campylobacteriosis; cranberries; diarrhea; feed supplements; gastroenteritis; gastrointestinal system; human cell lines; humans; livestock; oligosaccharides; pathogens; plant extracts; United States
Abstract:: ... Campylobacter infections are a leading cause of human bacterial gastroenteritis in the United States and are a major cause of diarrheal disease throughout the world. Colonization and subsequent infection and invasion of Campylobacter require that the bacteria adhere to the surface of host cells. Agents that inhibit adherence could be used prophylactically to reduce Campylobacter carriage and infec ...
DOI:: 10.4315/0362-028X.JFP-15-087
: https://doi.org/10.4315/0362-028X.JFP-15-087

21. Adsorption behavior and mechanisms of ciprofloxacin from aqueous solution by ordered mesoporous carbon and bamboo-based carbon

Author:: Xiaoming Peng; Fengping Hu; Frank L-Y Lam; Yajun Wang; Zhanmeng Liu; Hongling Dai
Source:: Journal of colloid and interface science 2015 v.460 pp. 349-360
ISSN:: 0021-9797
Subject:: adsorbents; adsorption; ammonia; antibiotics; aqueous solutions; carbon; ciprofloxacin; endothermy; heat treatment; hydrophobic bonding; ionic strength; models; nitrogen; pH; porous media; solubility; sorption isotherms; temperature; thermodynamics
Abstract:: ... The performances of ordered mesoporous carbon CMK-3 (OMC), bamboo-based carbon (BC), and these two kinds of adsorbents modified by thermal treatment in the ammonia atmosphere at high temperatures were evaluated for the removal fluoroquinolone antibiotic (ciprofloxacin) from aqueous solution. The adsorption behavior of ciprofloxacin (CIP) onto OMC and BC including adsorption isotherms and kinetics ...
DOI:: 10.1016/j.jcis.2015.08.050
: https://doi.org/10.1016/j.jcis.2015.08.050

22. Adsorption behavior of antibiotic in soil environment: a critical review

Author:: Shiliang Wang; Hui Wang
Source:: Frontiers of environmental science & engineering 2015 v.9 no.4 pp. 565-574
ISSN:: 2095-2201
Subject:: adsorption; antibiotics; composts; edaphic factors; emissions; excretion; humans; ionic strength; ionization; irrigation; metal ions; organic matter; pH; sewage; sludge; soil; veterinary medicine
Abstract:: ... Antibiotics are used widely in human and veterinary medicine, and are ubiquitous in environment matrices worldwide. Due to their consumption, excretion, and persistence, antibiotics are disseminated mostly via direct and indirect emissions such as excrements, sewage irrigation, and sludge compost and enter the soil and impact negatively the natural ecosystem of soil. Most antibiotics are amphiphil ...
DOI:: 10.1007/s11783-015-0801-2
: https://doi.org/10.1007/s11783-015-0801-2

23. Adsorption of enrofloxacin in presence of Zn(II) on a calcareous soil

Author:: Mareen Graouer-Bacart; Stéphanie Sayen; Emmanuel Guillon
Source:: Ecotoxicology and environmental safety 2015 v.122 pp. 470-476
ISSN:: 0147-6513
Subject:: X-radiation; absorption; adsorption; antibiotics; calcareous soils; cations; edaphic factors; enrofloxacin; excretion; groundwater; heavy metals; soil pH; sorption isotherms; spectroscopy; zinc
Abstract:: ... As a result of their consumption, excretion, disposal and persistence, antibiotics enter the soil environment and may be transported to surface and ground waters. During their transfer through soils, retention processes play a key role in their mobility. Antibiotics often coexist with heavy metals in soils due to agricultural practices and other sources of inputs. In this context, this study deals ...
DOI:: 10.1016/j.ecoenv.2015.09.019
: https://doi.org/10.1016/j.ecoenv.2015.09.019

24. Adsorptive Removal of Fluoroquinolone Antibiotics Using Bamboo Biochar

Author:: Yanbin Wang; Jian Lu; Jun Wu; Qing Liu; Hua Zhang; Song Jin
Source:: Sustainability 2015 v.7 no.9 pp. 12947-12957
ISSN:: 2071-1050
Subject:: adsorption; antibiotics; bamboos; biochar; enrofloxacin; ofloxacin; pH; sodium chloride; sorption isotherms; wastewater
Abstract:: ... The occurrence of fluoroquinolone antibiotics in wastewater has drawn great attention. Adsorption of widely used fluoroquinolone antibiotics (enrofloxacin and ofloxacin) in wastewater using bamboo biochar was investigated. More than 99% of fluoroquinolone antibiotics were removed from the synthetic wastewater through adsorption. Adsorption capacities of bamboo biochar slightly changed when pH incr ...
DOI:: 10.3390/su70912947
: https://doi.org/10.3390/su70912947

25. Advanced physico-chemical characterization of chitosan by means of TGA coupled on-line with FTIR and GCMS: Thermal degradation and water adsorption capacity

Author:: Ingrid Corazzari; Roberto Nisticò; Francesco Turci; Maria Giulia Faga; Flavia Franzoso; Silvia Tabasso; Giuliana Magnacca
Source:: Polymer degradation and stability 2015 v.112 pp. 1-9
ISSN:: 0141-3910
Subject:: Fourier transform infrared spectroscopy; adsorption; antibiotics; biopolymers; chitin; chitosan; coatings; differential scanning calorimetry; temperature; thermal degradation; thermal stability; thermogravimetry
Abstract:: ... In this study, chitosan, a commercially-available linear polysaccharide mainly used as antibacterial agent, functional coating and drug-delivery system, is investigated to enlighten both water interactions and its thermal stability by using a set of complementary advanced thermal techniques, rarely applied in polysaccharides characterizations. DSC and TGA, here coupled with FTIR and GCMS analysis ...
DOI:: 10.1016/j.polymdegradstab.2014.12.006
: https://doi.org/10.1016/j.polymdegradstab.2014.12.006

26. Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

Author:: Gamal M. Hamad; Tarek H. Taha; Nehal M. El-Deeb; Ali M. A. Alshehri
Source:: Journal of food science and technology 2015 v.52 no.12 pp. 8156-8163
ISSN:: 0022-1155
Subject:: Helicobacter pylori; adults; alkaloids; alternative medicine; amino acids; antibacterial properties; antibiotic resistance; antibiotics; bacteria; children; cloves; cumin; flavonoids; gastritis; ginger; humans; infants; licorice; milk; pathogens; pepper; plant extracts; pomegranates; proteins; proton pump inhibitors; reducing sugars; sage; saponins; stomach neoplasms; stomach ulcers; tannins; terpenoids
Abstract:: ... Helicobacter pylori is a common human pathogen infecting about 30 % of children and 60 % of adults worldwide. It is responsible for diseases such as gastritis, peptic ulcer and gastric cancer. H. pylori treatment based on antibiotics with proton pump inhibitor, but therapy failure is shown to be higher than 20 % and is essentially due to an increasing in prevalence of antibiotic-resistant bacteria ...
DOI:: 10.1007/s13197-015-1875-3
PubMed:: 26604389
PubMed Central:: PMC4648882
: https://doi.org/10.1007/s13197-015-1875-3

27. Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota

Author:: Han-Hsuan Chou; Wei-Hung Chien; Li-Ling Wu; Chi-Hung Cheng; Chen-Han Chung; Jau-Haw Horng; Yen-Hsuan Ni; Hong-Tai Tseng; Dafei Wu; Xuemei Lu; Hurng-Yi Wang; Pei-Jer Chen; Ding-Shinn Chen
Source:: Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.7 pp. 2175-2180
ISSN:: 0027-8424
Subject:: Hepatitis B virus; adaptive immunity; antibiotics; children; hepatitis B; intestinal microorganisms; liver; mice; models; neonates
Abstract:: ... A unique feature of hepatitis B virus (HBV) infection in humans is that viral clearance heavily depends on the age of exposure. However, the reason for this remains unclear. Here we show that gut microbiota contribute to the age dependence of HBV immunity in a hydrodynamic transfection mouse model. Although adult (12-wk-old) C3H/HeN mice cleared HBV within 6 wk postinjection (wpi), their young (6- ...
DOI:: 10.1073/pnas.1424775112
PubMed:: 25646429
PubMed Central:: PMC4343154
: https://doi.org/10.1073/pnas.1424775112

28. Aggressive, Solid Variant of Alveolar Rhabdomyosarcoma with Cutaneous Involvement in a Juvenile Labrador Retriever

Author:: I. Otrocka-Domagala; K. Pazdzior-Czapula; M. Gesek; M. Koda; M. Mikiewicz; A. Mikolajczyk
Source:: Journal of comparative pathology 2015 v.152 no.2-3 pp. 177-181
ISSN:: 0021-9975
Subject:: Labrador Retriever; actin; antibiotics; desmin; dogs; gingiva; immunohistochemistry; juveniles; major histocompatibility complex; males; neck; necropsy; neoplasm cells; nests; phosphopyruvate hydratase; skeletal muscle; skin neoplasms; smooth muscle; vimentin
Abstract:: ... An 8.5-month-old male Labrador retriever presented with a cutaneous mass in the right maxillofacial region and swelling of the gingiva. The dog received antibiotic and anti-inflammatory treatment. After 3 weeks the dog returned, presenting with disseminated cutaneous tumours on the neck, trunk and groin. One of the nodules was resected and a cutaneous round cell tumour was diagnosed on microscopic ...
DOI:: 10.1016/j.jcpa.2014.11.004
: https://doi.org/10.1016/j.jcpa.2014.11.004

29. Agronomic and environmental effects of land application of residues in short-rotation tree plantations: A literature review

Author:: Nicolas Marron
Source:: Biomass and bioenergy 2015 v.81 pp. 378-400
ISSN:: 0961-9534
Subject:: Eucalyptus; antibiotics; composts; coppicing; death; effluents; growth retardation; heavy metals; land application; leaching; leaves; nutrients; plant growth; plantations; recycling; sewage sludge; soil; soil nutrients; transpiration; wastewater; water pollution
Abstract:: ... Land application of residues in short-rotation plantation has a priori the double advantage to meet the nutrient needs of these tree plantations at lower cost while recycling residues. Agronomic and environmental effects of a very wide variety of residues on plants and soils have been studied worldwide. I attempt here to compile and to summarize the results of the studies about the effects of land ...
DOI:: 10.1016/j.biombioe.2015.07.025
: https://doi.org/10.1016/j.biombioe.2015.07.025

30. Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

Author:: A.J. Brink; G.A. Richards; E.E.G. Lautenbach; N. Rapeport; V. Schillack; L. van Niekerk; J. Lipman; J.A. Roberts
Source:: International journal of antimicrobial agents 2015 v.45 no.6 pp. 647-651
ISSN:: 0924-8579
Subject:: antibiotics; blood; chromatography; debridement; drugs; hypoalbuminemia; intravenous injection; monitoring; patients; pharmacokinetics; regression analysis; sepsis (infection); serum albumin
Abstract:: ... The impact of decreased serum albumin concentrations on free antibiotic concentrations in non-critically ill patients is poorly described. This study aimed to describe the pharmacokinetics of a high-dose regimen of teicoplanin, a highly protein-bound antibiotic, in non-critically ill patients with hypoalbuminaemia. Ten patients with chronic bone sepsis and decreased serum albumin concentrations (< ...
DOI:: 10.1016/j.ijantimicag.2015.01.015
: https://doi.org/10.1016/j.ijantimicag.2015.01.015

31. Alicyclobacillus in the Fruit Juice Industry: Spoilage, Detection, and Prevention/Control

Author:: Xiao-Chen Huang; Ya-Hong Yuan; Chun-Feng Guo; Vassilis Gekas; Tian-Li Yue
Source:: Food reviews international 2015 v.31 no.2 pp. 91-124
ISSN:: 1525-6103
Subject:: Alicyclobacillus; acid tolerance; antibiotics; fruit juices; juice industry; off flavors; pasteurization; sediments; spoilage; spore-forming bacteria
Abstract:: ... Alicyclobacillus spp. are heat-resistant, acid-tolerant spore-forming bacteria that could survive in commercial pasteurized fruit juice and cause spoilage along with the production of medical, phenolic, or antiseptic off-flavor, with or without visible sediment. As spoilage poses a great challenge to fruit juice industry, the aim of the present paper has been twofold. Firstly, to explore various i ...
DOI:: 10.1080/87559129.2014.974266
: https://doi.org/10.1080/87559129.2014.974266

32. Allopurinol-mediated lignocellulose-derived microbial inhibitor tolerance by Clostridium beijerinckii during acetone–butanol–ethanol (ABE) fermentation

Author:: Victor Ujor; Chidozie Victor Agu; Venkat Gopalan; Thaddeus Chukwuemeka Ezeji
Source:: Applied microbiology and biotechnology 2015 v.99 no.8 pp. 3729-3740
ISSN:: 0175-7598
Subject:: Clostridium beijerinckii; DNA repair; NAD (coenzyme); allopurinol; antibiotics; arabinans; biofuels; biomass; biotechnology; butanol; culture media; fermentation; furfural; glucans; hydrolysates; hypoxanthine; lignocellulose; messenger RNA; microorganisms; nalidixic acid; reducing agents; toxicity; xanthine; xanthine dehydrogenase
Abstract:: ... In addition to glucans, xylans, and arabinans, lignocellulosic biomass hydrolysates contain significant levels of nonsugar components that are toxic to the microbes that are typically used to convert biomass to biofuels and chemicals. To enhance the tolerance of acetone–butanol–ethanol (ABE)-generating Clostridium beijerinckii NCIMB 8052 to these lignocellulose-derived microbial inhibitory compoun ...
DOI:: 10.1007/s00253-015-6450-3
: https://doi.org/10.1007/s00253-015-6450-3

33. Alpha amylase assisted synthesis of TiO2 nanoparticles: Structural characterization and application as antibacterial agents

Author:: Razi Ahmad; Mohd Mohsin; Tokeer Ahmad; Meryam Sardar
Source:: Journal of hazardous materials 2015 v.283 pp. 171-177
ISSN:: 0304-3894
Subject:: Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus aureus; X-ray diffraction; alpha-amylase; antibacterial properties; antibiotics; bacteria; cell walls; confocal microscopy; minimum inhibitory concentration; nanoparticles; titanium dioxide; transmission electron microscopy
Abstract:: ... The enzyme alpha amylase was used as the sole reducing and capping agent for the synthesis of TiO2 nanoparticles. The biosynthesized nanoparticles were characterized by X-ray diffraction (XRD) and transmission electron microscopic (TEM) methods. The XRD data confirms the monophasic crystalline nature of the nanoparticles formed. TEM data shows that the morphology of nanoparticles depends upon the ...
DOI:: 10.1016/j.jhazmat.2014.08.073
: https://doi.org/10.1016/j.jhazmat.2014.08.073

34. Alterations in the antibacterial potential of Synechococcus spp. PCC7942 under the influence of UV-B radiations on skin pathogens

Author:: Nida Fatima; Iffat Zareen Ahmad; Hera Chaudhry
Source:: Saudi Journal of Biological Sciences 2015 pp. -
ISSN:: 1319-562X
Subject:: Synechococcus; active oxygen species; algicides; antibacterial properties; antibiotics; antioxidants; aquatic organisms; bacteria; bioactive compounds; carotenoids; cytotoxicity; dose response; drugs; metabolites; methanol; pathogens; phycocyanin; solvents; ultraviolet radiation
Abstract:: ... Marine organisms are seen as a source of novel drugs and the discovery of new pharmaceutical is increasingly in demand. Cyanobacteria are regarded as a potential target for this as antibacterial, antiviral, antifungal, algicide and cytotoxic activities have been reported in these organisms. They have been identified as a new and rich source of bioactive compounds belonging to diversified groups. R ...
DOI:: 10.1016/j.sjbs.2015.10.014
PubMed:: 30294232
PubMed Central:: PMC6169429
: https://doi.org/10.1016/j.sjbs.2015.10.014

35. Alternative routes to the acylphloroglucinol rhodomyrtone

Author:: Marius Morkunas; Martin E. Maier
Source:: Tetrahedron 2015 v.71 pp. 9662-9666
ISSN:: 0040-4020
Subject:: antibiotics; chemical reactions; chemical structure; organic compounds
Abstract:: ... Two novel routes to the acylphloroglucinol rhodomyrtone (1) which has antibiotic properties are presented. In the first route an ortho-quinone methide, generated from dioxaborinine 23, is reacted with syncarpic acid (10) leading to xanthenedione 25. Cleavage of the methyl ether functions led to the known rhodomyrtone precursor 16. In the second route the bis-ester derivative 28 of trihydroxybenzal ...
DOI:: 10.1016/j.tet.2015.10.063
: https://doi.org/10.1016/j.tet.2015.10.063

36. Amodiaquine–Ciprofloxacin: a potential combination therapy against drug resistant malaria

Author:: Y. F. FALAJIKI; O. AKINOLA; O. O. ABIODUN; C. T. HAPPI; A. SOWUNMI; G. O. GBOTOSHO
Source:: Parasitology 2015 v.142 no.6 pp. 849-854
ISSN:: 1469-8161
Subject:: Plasmodium berghei; antibiotics; artemisinin; body weight; ciprofloxacin; drug resistance; malaria; mice; parasitemia; parasites; survival rate; therapeutics
Abstract:: ... Emergence of malaria parasites resistant to artemisinin necessitates the need for development of new antimalarial therapies. Ciprofloxacin (CFX) a second generation quinolone antibiotic possesses some antimalarial activities. We investigated the in vivo antimalarial activities of CFX in combination with amodiaquine in mice infected with chloroquine-resistant Plasmodium berghei ANKA. Animals were t ...
DOI:: 10.1017/S0031182015000062
PubMed:: 25736371
: https://doi.org/10.1017/S0031182015000062

37. Analysis and evaluation of antibacterial effects of new herbal formulas, AP-001 and AP-002, against Escherichia coli O157:H7

Author:: Mohammadreza Rezaei Golestani; Mehrnaz Rad; Mohammadreza Bassami; Amir Afkhami-Goli
Source:: Life sciences 2015 v.135 pp. 22-26
ISSN:: 0024-3205
Subject:: Allium cepa; Allium sativum; Dianthus caryophyllus; Escherichia coli O157; Eucalyptus globulus; Mentha piperita; Mentha spicata; Salvia officinalis; Thymus vulgaris; antibacterial properties; antibiotic resistance; antibiotics; clinical trials; essential oils; herbal medicines; medicine; microorganisms; minimum inhibitory concentration; poultry industry
Abstract:: ... Over the last few years, there has been an increasing interest in the use of natural substances for promoting human and animal health. Antibiotic resistance, enhanced by excessive use of antibiotics, has encouraged human and animal health authorities to consider and employ alternative approaches, including herbal and botanical medicine to combat invading microorganisms. Herein, the essential oils ...
DOI:: 10.1016/j.lfs.2015.05.007
: https://doi.org/10.1016/j.lfs.2015.05.007

38. Analysis of a draft genome sequence of Kitasatospora cheerisanensis KCTC 2395 producing bafilomycin antibiotics

Author:: Jae Yoon Hwang; Soo Hee Kim; Hye Ryeung Oh; Eunju Kwon; Doo Hyun Nam
Source:: journal of microbiology 2015 v.53 no.1 pp. 84-89
ISSN:: 1225-8873
Subject:: Kitasatospora cheerisanensis; Mycobacterium tuberculosis; Saccharopolyspora erythraea; Streptomyces; antibiotics; biosynthesis; cell division; cell walls; loci; microbiology; multigene family; mycelium; open reading frames; phylogeny; polyketide synthases; soil; spores; substrate specificity; Korean Peninsula
Abstract:: ... Kitasatospora cheerisanensis KCTC 2395, producing bafilomycin antibiotics belonging to plecomacrolide group, was isolated from a soil sample at Mt. Jiri, Korea. The draft genome sequence contains 8.04 Mb with 73.6% G+C content and 7,810 open reading frames. All the genes for aerial mycelium and spore formations were confirmed in this draft genome. In phylogenetic analysis of MurE proteins (UDP-N-a ...
DOI:: 10.1007/s12275-015-4340-0
: https://doi.org/10.1007/s12275-015-4340-0

39. Analysis of swine fecal microbiota at various growth stages

Author:: Jungman Kim; Son G. Nguyen; Robin B. Guevarra; Iljoo Lee; Tatsuya Unno
Source:: Archives of microbiology 2015 v.197 no.6 pp. 753-759
ISSN:: 0302-8933
Subject:: antibiotics; bacteria; bacterial communities; developmental stages; energy; feed additives; growth promotion; humans; intestinal microorganisms; nucleotide sequences; obesity; ribosomal RNA; rodents; swine; weight gain
Abstract:: ... Recent obesity studies in humans and rodents have suggested that host weight gain is significantly associated with energy harvesting efficiency which is regulated by gut microbiota. Antibiotic growth promoters have been banned as feed additives in many countries. In this study, we aimed to provide knowledge of swine fecal microbiota by analyzing bacterial 16S rRNA gene sequences. Our results showe ...
DOI:: 10.1007/s00203-015-1108-1
: https://doi.org/10.1007/s00203-015-1108-1

40. Anti-infective vaccination in the 21st century—new horizons for personal and public health

Author:: Ingrid L Scully; Kena Swanson; Luke Green; Kathrin U Jansen; Annaliesa S Anderson
Source:: Current opinion in microbiology 2015 v.27 pp. 96-102
ISSN:: 1369-5274
Subject:: Clostridium difficile; Staphylococcus aureus; animal pathogens; antibiotic resistance; antibiotics; bacteria; disease control; disease severity; flora; humans; public health; risk; vaccination; vaccine development; vaccines
Abstract:: ... The 21st century has seen the licensure of new anti-infective vaccines that have demonstrated their benefit for both individual and population (herd) protection. Despite this there are still many human pathogens for which no vaccine is available. As we learn more about these pathogens, and as technologies advance, more opportunities for vaccine development have become available. This review will a ...
DOI:: 10.1016/j.mib.2015.07.006
: https://doi.org/10.1016/j.mib.2015.07.006

41. Antibacterial Activities of Metabolites from Platanus occidentalis (American sycamore) against Fish Pathogenic Bacteria

Author:: Kevin K. Schrader; Mark T. Hamann; James D. McChesney; Douglas L. Rodenburg; Mohamed A. Ibrahim
Source:: Journal of aquaculture research & development 2015 v.6 no.10 pp. 364
ISSN:: 2155-9546
Subject:: Aeromonas hydrophila; Edwardsiella ictaluri; Flavobacterium columnare; Platanus occidentalis; Streptococcus iniae; animal pathogenic bacteria; antibacterial properties; antibiotic resistance; antibiotics; aquaculture; aquaculture industry; bioassays; columnaris disease; fish; isomers; kaempferol; leaves; medicated feeds; metabolites; research and development; trees
Abstract:: ... One approach to the management of common fish diseases in aquaculture is the use of antibiotic-laden feed. However, there are public concerns about the use of antibiotics in agriculture and the potential development of antibiotic resistant bacteria. Therefore, the discovery of other environmentally safe natural compounds as alternatives to antibiotics would benefit the aquaculture industries. Four ...
Handle:: 10113/62231
DOI:: 10.4172/2155-9546.1000364
PubMed:: 27790379
PubMed Central:: PMC5079432
: https://doi.org/10.4172/2155-9546.1000364

42. Antibacterial Activity of Helichrysum italicum Oil on Vegetables and Its Mechanism of Action

Author:: Haiying Cui; Chengting Zhao; Lin Lin
Source:: Journal of food processing and preservation 2015 v.39 no.6 pp. 2663-2672
ISSN:: 0145-8892
Subject:: DNA; Escherichia coli; Helichrysum italicum; Staphylococcus aureus; acetates; adenosine triphosphate; antibacterial properties; antibiotics; bacteria; cell membranes; chemical composition; gas chromatography-mass spectrometry; mechanism of action; minimum inhibitory concentration; spices; vegetable oil; vegetables
Abstract:: ... In the present paper, the chemical composition of Helichrysum italicum oil was analyzed by gas chromatography–mass spectrometry (GC‐MS). Neryl acetate (32.65%) was the main component. The minimum inhibitory concentration and minimum bactericidal concentration of H. italicum oil against several bacteria were evaluated. The results showed that H. italicum oil exhibited high antibacterial activity ag ...
DOI:: 10.1111/jfpp.12516
: https://doi.org/10.1111/jfpp.12516

43. Antibacterial Coatings: Challenges, Perspectives, and Opportunities

Author:: M. Cloutier; D. Mantovani; F. Rosei
Source:: Trends in biotechnology 2015 v.33 pp. 637-652
ISSN:: 0167-7799
Subject:: antibacterial properties; antibiotics; biotechnology; coatings; microbiology; pathogens
Abstract:: ... Antibacterial coatings are rapidly emerging as a primary component of the global mitigation strategy of bacterial pathogens. Thanks to recent concurrent advances in materials science and biotechnology methodologies, and a growing understanding of environmental microbiology, an extensive variety of options are now available to design surfaces with antibacterial properties. However, progress towards ...
DOI:: 10.1016/j.tibtech.2015.09.002
: https://doi.org/10.1016/j.tibtech.2015.09.002

44. Antibacterial Effects of Cinnamon: From Farm to Food, Cosmetic and Pharmaceutical Industries

Author:: Seyed Fazel Nabavi; Arianna Di Lorenzo; Morteza Izadi; Eduardo Sobarzo-Sánchez; Maria Daglia; Seyed Mohammad Nabavi
Source:: Nutrients 2015 v.7 no.9 pp. 7729-7748
ISSN:: 2072-6643
Subject:: Cinnamomum; antibacterial properties; antibiotics; chemical constituents of plants; cinnamon; cosmetics; farms; food pathogens; foods; herbs; hypersensitivity; infectious diseases; medicinal plants; pharmaceutical industry; risk reduction; shelf life; spoilage bacteria; traditional medicine
Abstract:: ... Herbs and spices have been used since ancient times, because of their antimicrobial properties increasing the safety and shelf life of food products by acting against foodborne pathogens and spoilage bacteria. Plants have historically been used in traditional medicine as sources of natural antimicrobial substances for the treatment of infectious disease. Therefore, much attention has been paid to ...
DOI:: 10.3390/nu7095359
PubMed:: 26378575
PubMed Central:: PMC4586554
: https://doi.org/10.3390/nu7095359

45. Antibacterial Networks Based on Isosorbide and Linalool by Photoinitiated Process

Author:: Modjinou Tina; Versace Davy-Louis; Abbad-Andallousi Samir; Bousserrhine Noureddine; Babinot Julien; Langlois Valérie; Renard Estelle
Source:: ACS sustainable chemistry 2015 v.3 no.6 pp. 1094-1100
ISSN:: 2168-0485
Subject:: Escherichia coli; Staphylococcus aureus; adhesion; antibacterial properties; antibiotics; bacteria; coatings; crosslinking; linalool; solvents
Abstract:: ... In this study, we used photo-induced thiol-ene reactions to design bio-based cross-linked networks from diallyl derivative isosorbide, a crude monoterpene as linalool and a trithiol. The aim of this study is to prepare new antibacterial UV-cured networks by using a thiol-ene formulation with covalent immobilization of monoterpenes as antibacterial agents and without any organic solvent thanks to t ...
DOI:: 10.1021/acssuschemeng.5b00018
: https://doi.org/10.1021/acssuschemeng.5b00018

46. Antibacterial Properties of Nutmeg Oil in Pork and Its Possible Mechanism

Author:: Haiying Cui; Xuejing Zhang; Hui Zhou; Chengting Zhao; Zhihong Xiao; Lin Lin; Changzhu Li
Source:: Journal of food safety 2015 v.35 no.3 pp. 370-377
ISSN:: 0149-6085
Subject:: DNA; Escherichia coli; Staphylococcus aureus; adenosine triphosphate; alpha-pinene; antibacterial properties; antibiotics; bacteria; cell membranes; fluorescence; gas chromatography-mass spectrometry; hygiene; minimum inhibitory concentration; nutmeg; oils; pathogens; pork; sabinene; scanning electron microscopy; spoilage; volatile compounds
Abstract:: ... The aim of this study is to investigate the antibacterial characteristics and mechanisms of nutmeg oil. In this paper, 54 chemical compositions of nutmeg oil were analyzed by gas chromatography–mass spectrometry (GC–MS). The major volatile components of nutmeg oil were sabinene (39.12%) and alpha‐pinene (11.96%). In addition, nutmeg oil showed significant antibacterial activity, minimum inhibitory ...
DOI:: 10.1111/jfs.12184
: https://doi.org/10.1111/jfs.12184

47. Antibacterial activities of TiO₂ nanotubes on Porphyromonas gingivalis

Author:: Xiaoguo Shi; Quan Xu; Ang Tian; Yulou Tian; Xiangxin Xue; Hongjing Sun; He Yang; Chenbo Dong
Source:: RSC advances 2015 v.5 no.43 pp. 34237-34242
ISSN:: 2046-2069
Subject:: Porphyromonas gingivalis; antibacterial properties; antibiotics; antiseptics; bacteria; bacterial growth; biocompatible materials; coatings; decontamination; dental prosthesis; growth retardation; hydrophilicity; irradiation; nanotubes; oxidation; oxidative stress; photocatalysis; titanium dioxide; ultraviolet radiation
Abstract:: ... Titanium-based nanomaterials have been widely used as dental implants because of their beneficial antiseptic and nano-interfacial effects. In particular, their application as surface decontamination biocompatible materials attracts increasing attention. In this study, a TiO₂ nanotube-based antibacterial system has been fabricated by an anodic oxidation method, and its morphology, crystalline phase ...
DOI:: 10.1039/c5ra00804b
: https://doi.org/10.1039/c5ra00804b

48. Antibacterial amphiphiles based on ε-polylysine: synthesis, mechanism of action, and cytotoxicity

Author:: Xiaomei Dai; Jinxia An; Yanan Wang; Zhongming Wu; Yu Zhao; Qianqian Guo; Xinge Zhang; Chaoxing Li
Source:: RSC advances 2015 v.5 no.85 pp. 69325-69333
ISSN:: 2046-2069
Subject:: Bacillus amyloliquefaciens; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; adsorption; alkylation; antibacterial properties; antibiotic resistance; antibiotics; bacteria; cytoplasm; cytotoxicity; electrostatic interactions; hydrophobic bonding; lipids; mechanism of action; minimum inhibitory concentration; organobromine compounds; surfactants
Abstract:: ... The development of antibacterial materials is recently more and more important and urgent due to the emergence of antibiotic-resistant bacteria. To address the problem, series of new amphiphiles based on ε-polylysine (ε-PL) were synthesized by alkylation reaction with alkyl bromide, and concurrently their antibacterial activity and cytotoxicity were evaluated. The amphiphiles with a large concentr ...
DOI:: 10.1039/c5ra10393b
: https://doi.org/10.1039/c5ra10393b

49. Antibacterial and osteoinductive capability of orthopedic materials via cation–π interaction mediated positive charge

Author:: Lianxin Shi; Wei Zhang; Kun Yang; Haigang Shi; Dan Li; Jun Liu; Junhui Ji; Paul K. Chu
Source:: Journal of materials chemistry B 2015 v.3 no.5 pp. 733-737
ISSN:: 2050-7518
Subject:: antibacterial properties; antibiotics; biomedical materials; bone formation; coatings; dipping; mesenchymal stromal cells; orthopedics; polymers; prostheses; viability
Abstract:: ... Both implant centered infection and deficient osteoinduction are pivotal issues for orthopedic implants in early and long-term osseointegration, but constructing a functional bio-interface that can overcome these two problems is highly challenging. Our study reveals that a bio-interface with promoted positive charges plays an active role in simultaneously enhancing the antibacterial and osteoinduc ...
DOI:: 10.1039/c4tb01924e
: https://doi.org/10.1039/c4tb01924e

50. Antibacterial compounds from Salvia adenophora Fernald (Lamiaceae)

Author:: Angela Bisio; Anna Maria Schito; Samad Nejad Ebrahimi; Matthias Hamburger; Giacomo Mele; Gabriella Piatti; Giovanni Romussi; Fabrizio Dal Piaz; Nunziatina De Tommasi
Source:: Phytochemistry 2015 v.110 pp. 120-132
ISSN:: 0031-9422
Subject:: Candida albicans; Salvia; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus agalactiae; aerial parts; anti-infective properties; antibiotics; diterpenoids; multiple drug resistance; nuclear magnetic resonance spectroscopy; oxylipins; pathogens; plant extracts
Abstract:: ... From the aerial parts of Salvia adenophora Fernald four derivatives of 12-oxo-phytodienoic acid (1–4) together with five clerodane diterpenoids (5, 6, 8–10), and one known diterpene (7) have been isolated. Compounds 1–6 and 8–10 are described for the first time. The structures were established by extensive 1D, 2D NMR and HRESI-TOFMS spectroscopic methods. Finally, the absolute configuration has be ...
DOI:: 10.1016/j.phytochem.2014.10.033
: https://doi.org/10.1016/j.phytochem.2014.10.033

51. Antibacterial effect of silver nanoparticles and the modeling of bacterial growth kinetics using a modified Gompertz model

Author:: Tanaya Chatterjee; Barun K. Chatterjee; Dipanwita Majumdar; Pinak Chakrabarti
Source:: BBA - General Subjects 2015 v.1850 pp. 299-306
ISSN:: 0304-4165
Subject:: 4',6-diamidino-2-phenylindole; DNA; Escherichia coli; Staphylococcus aureus; absorbance; antibacterial properties; antibiotics; bacteria; cell death; death; fluorescence; fluorescence microscopy; growth models; logit analysis; microbial growth; mortality; multiple drug resistance; nanosilver; reactive oxygen species; scanning electron microscopy
Abstract:: ... An alternative to conventional antibiotics is needed to fight against emerging multiple drug resistant pathogenic bacteria. In this endeavor, the effect of silver nanoparticle (Ag-NP) has been studied quantitatively on two common pathogenic bacteria Escherichia coli and Staphylococcus aureus, and the growth curves were modeled.The effect of Ag-NP on bacterial growth kinetics was studied by measuri ...
DOI:: 10.1016/j.bbagen.2014.10.022
: https://doi.org/10.1016/j.bbagen.2014.10.022

52. Antibacterial evaluation of flavonoid compounds against E. coli by microcalorimetry and chemometrics

Author:: Weijun Kong; Yanling Zhao; Xiaoyan Xing; Xinping Ma; Xiaojiao Sun; Meihua Yang; Xiaohe Xiao
Source:: Applied microbiology and biotechnology 2015 v.99 no.14 pp. 6049-6058
ISSN:: 0175-7598
Subject:: Escherichia coli; antibacterial properties; antibiotics; bacteria; chemometrics; flavonoids; heat; inhibitory concentration 50; monitoring; multiple drug resistance; multivariate analysis; principal component analysis; skeleton
Abstract:: ... Fighting against multidrug-resistant bacteria requires reliable methods to evaluate the effect of antibacterial agents. As a universal, non-destructive, and highly sensitive tool, microcalorimetry has been used in many biological investigations to provide continuous real-time monitoring of the metabolic activity. This method, based on heat-flow output, was used to evaluate the influence of two fla ...
DOI:: 10.1007/s00253-015-6711-1
: https://doi.org/10.1007/s00253-015-6711-1

53. Antibacterial mechanism of the action of Enteromorpha linza L. essential oil against Escherichia coli and Salmonella Typhimurium

Author:: Jayanta Kumar Patra; Gitishree Das; Kwang-Hyun Baek
Source:: Botanical studies 2015 v.56 no.1 pp. 13
ISSN:: 1999-3110
Subject:: Escherichia coli; Gram-negative bacteria; Gram-positive bacteria; Salmonella Typhimurium; Ulva; acids; alkenes; antibacterial properties; antibiotics; chemical composition; cytosol; electrical conductivity; enzymes; essential oils; food pathogens; mechanism of action; minimum inhibitory concentration; models; potassium; salt tolerance; viability
Abstract:: ... BACKGROUND: Identification of natural antibacterial agents from various sources that can act effectively against disease causing foodborne bacteria is one of the major concerns throughout the world. However, the natural antibacterial agents identified to date are primarily effective against Gram positive bacteria, but less effective against Gram negative bacteria. In the present study, Enteromorph ...
DOI:: 10.1186/s40529-015-0093-7
PubMed:: 28510822
PubMed Central:: PMC5432928
: https://doi.org/10.1186/s40529-015-0093-7

54. Antibacterial mode of action of the hydroethanolic extract of Leonotis nepetifolia (L.) R. Br. involves bacterial membrane perturbations

Author:: Darley Maria Oliveira; Fernanda Germano Melo; Sikiru Olaitan Balogun; Adriana Flach; Edineide Cristina Alexandre de Souza; Gilmar Prado de Souza; Iolanda do Nascimento Araújo Rocha; Luiz Antonio Mendonça Alves da Costa; Ilsamar Mendes Soares; Larissa Irene da Silva; Sérgio Donizeti Ascêncio; Domingos Tabajara de Oliveira Martins
Source:: Journal of ethnopharmacology 2015 v.172 pp. 356-363
ISSN:: 0378-8741
Subject:: Bacillus subtilis; Enterococcus faecalis; Helicobacter pylori; Leonotis; Shigella flexneri; Staphylococcus aureus; Streptococcus pyogenes; antibacterial properties; antibiotics; bacteria; carotenoids; cell membranes; cytotoxicity; fatty acids; flavonoids; hydrophobicity; in vitro studies; inhibitory concentration 50; leaves; mechanism of action; permeability; phenol; potassium; secondary metabolites; shrubs; steroids; stomach; traditional medicine; Brazil
Abstract:: ... Leonotis nepetifolia (L) R. Br., Lamiaceae, a pantropical shrub, popularly known in Brazil as “cordão-de-frade”, “rubim”, is reportedly used in Brazilian ethnomedicine as well as in different countries in the treatments of ailments such as infections, inflammations, wounds, stomach disorders, among others.To evaluate its potential cytotoxicity and antibacterial mode of action of the hydroethanolic ...
DOI:: 10.1016/j.jep.2015.06.027
: https://doi.org/10.1016/j.jep.2015.06.027

55. Antibacterial monoclonal antibodies: the next generation?

Author:: Antonio DiGiandomenico; Bret R Sellman
Source:: Current opinion in microbiology 2015 v.27 pp. 78-85
ISSN:: 1369-5274
Subject:: antibiotic resistance; antibiotics; bacteria; bacterial infections; engineering; microbiome; monoclonal antibodies; pathogens; physicians; resistance mechanisms; therapeutics
Abstract:: ... There is a clear need for renewed efforts to combat the increasing incidence of antibiotic resistance. While the antibiotic resistance epidemic is due in part to the misuse of antibiotics, even proper empiric antibiotic therapy increases the selective pressure and potential for drug-resistance and spread of resistance mechanisms between bacteria. Antibiotic resistance coupled with the detrimental ...
DOI:: 10.1016/j.mib.2015.07.014
: https://doi.org/10.1016/j.mib.2015.07.014

56. Antibacterial poly(ethylene terephthalate) surfaces obtained from thymyl methacrylate polymerization

Author:: Sophie Bedel; Bénédicte Lepoittevin; Ludovic Costa; Olivier Leroy; Diana Dragoe; Jérôme Bruzaud; Jean‐Marie Herry; Morgan Guilbaud; Marie‐Noëlle Bellon‐Fontaine; Philippe Roger
Source:: Journal of polymer science 2015 v.53 no.17 pp. 1975-1985
ISSN:: 0887-624X
Subject:: Listeria monocytogenes; Pseudomonas aeruginosa; Staphylococcus aureus; X-ray photoelectron spectroscopy; ammonia; antibiotics; bacterial adhesion; energy; polyethylene terephthalates; polymerization; thymol
Abstract:: ... Thymol, an antibacterial agent was used for the preparation of a methacrylic monomer. The conventional and atom transfer radical (ATRP) polymerizations of this monomer were studied using different conditions. Then, the functionalization of poly(ethylene terephthalate) (PET) films by “grafting from” ATRP using this monomer was investigated. In this aim, a three steps procedure was developed. The su ...
DOI:: 10.1002/pola.27647
: https://doi.org/10.1002/pola.27647

57. Antibacterial products of marine organisms

Author:: Tzi Bun Ng; Randy Chi Fai Cheung; Jack Ho Wong; Adnan A. Bekhit; Alaa El-Din Bekhit
Source:: Applied microbiology and biotechnology 2015 v.99 no.10 pp. 4145-4173
ISSN:: 0175-7598
Subject:: Gram-negative bacteria; Gram-positive bacteria; animal models; antibacterial properties; antibiotics; bacterial infections; drug resistance; invertebrates; mammals; peptides; proteins; synergism; tissues; toxicity
Abstract:: ... Marine organisms comprising microbes, plants, invertebrates, and vertebrates elaborate an impressive array of structurally diverse antimicrobial products ranging from small cyclic compounds to macromolecules such as proteins. Some of these biomolecules originate directly from marine animals while others arise from microbes associated with the animals. It is noteworthy that some of the biomolecules ...
DOI:: 10.1007/s00253-015-6553-x
: https://doi.org/10.1007/s00253-015-6553-x

58. Antibacterial properties and cytocompatibility of bio-based nanostructured carbon aerogels derived from silver nanoparticles deposited onto bacterial cellulose

Author:: Ning Yan; Yabin Zhou; Yudong Zheng; Shuang Qiao; Qun Yu; Zhongzheng Li; Haiyang Lu
Source:: RSC advances 2015 v.5 no.118 pp. 97467-97476
ISSN:: 2046-2069
Subject:: Escherichia coli; Staphylococcus aureus; aerogels; antibacterial properties; antibiotics; carbon; carbonization; cellulose; drugs; fluorescence microscopy; hydrophobicity; mechanical properties; nanosilver; resorption; scanning electron microscopy; silver; toxicity testing
Abstract:: ... An AgNP (silver nanoparticle)-deposited bio-based nanostructured carbon aerogel (denoted as p-BC/AgNP) with a three-dimensional (3D) porous network structure was fabricated by carbonizing AgNP bacterial cellulose (denoted as BC/AgNP). The unique 3D nano-network structure gave the hydrophobic p-BC/AgNP good mechanical properties and water reabsorption capacity. AgNPs uniformly dispersed onto the fi ...
DOI:: 10.1039/c5ra15485e
: https://doi.org/10.1039/c5ra15485e

59. Antibacterial properties of extracts of Ludwigia peploides subsp. montevidensis and Ludwigia grandiflora subsp. hexapetala during their cycle of development

Author:: Imen Smida; Claude Charpy-Roubaud; Souhila Yahia Cherif; Franck Torre; Gérard Audran; Samira Smiti; Jean Le Petit
Source:: Aquatic botany 2015 v.121 pp. 39-45
ISSN:: 0304-3770
Subject:: Gram-negative bacteria; Ludwigia grandiflora; Ludwigia peploides; Salmonella enterica; Staphylococcus aureus; antibacterial properties; antibiotics; aquatic ecosystems; aquatic plants; dimethyl sulfoxide; flowers; leaves; plant extracts; plant organs; principal component analysis; France
Abstract:: ... Ludwigia peploides subsp. montevidensis and Ludwigia grandiflora subsp. hexapetala, form aquatic dense stands, which cause major ecological and economical problems in many aquatic ecosystems in France. However, these species are known to release allelopathic compounds. Here, antibacterial properties were assessed on samples from different plant organs, during June, July and August for L. peploides ...
DOI:: 10.1016/j.aquabot.2014.10.011
: https://doi.org/10.1016/j.aquabot.2014.10.011

60. Antibacterial, antifungal and cytotoxic activities exhibited by endophytic fungi from the Brazilian marine red alga Bostrychia tenella (Ceramiales)

Author:: Rafael de Felício; Gabriel B. Pavão; Ana Lígia L. de Oliveira; Cíntia Erbert; Raphael Conti; Monica T. Pupo; Niege A.J.C. Furtado; Elthon G. Ferreira; Letícia V. Costa-Lotufo; Maria Cláudia M. Young; Nair S. Yokoya; Hosana M. Debonsi
Source:: Revista Brasileira de Farmacognosia 2015 v.25 no.6 pp. 641-650
ISSN:: 0102-695X
Subject:: Khuskia oryzae; endophytes; macroalgae; rice; antibiotics; Ceramiales; cytotoxicity; marine environment; Xylaria; fungi; Trichoderma atroviride; Acremonium; cytochalasin D; habitats; Penicillium; metabolites; antibacterial properties
Abstract:: ... Marine environment is one of the most important sources regarding natural products research. Besides, marine microorganisms have been denominated as a talented natural source for discovery of new leads. Although the association of macroalgae and fungi has been described regarding ecological issues, there is a lack of studies about marine seaweed endophytic fungi. In this context, the goal of this ...
DOI:: 10.1016/j.bjp.2015.08.003
: https://doi.org/10.1016/j.bjp.2015.08.003

61. Antibiotic Activity of Iron-Sequestering Polymers

Author:: El-Gendy Nashwa; Qian Jian; Eshelman Kate; Rivera Mario; Berkland Cory
Source:: Biomacromolecules 2015 v.16 no.5 pp. 1480-1488
ISSN:: 1526-4602
Subject:: Pseudomonas aeruginosa; adjuvants; antibacterial properties; antibiotic resistance; antibiotics; bacterial infections; biomimetics; chelating agents; crosslinking; culture media; gels; iron; microbial growth; polymers; therapeutics
Abstract:: ... Increasing antibiotic resistance has compelled the development of novel antibiotics and adjuvant therapies that enhance the efficacy of existing antibiotics. Iron plays a critical role in bacterial infections, yet the use of iron chelators as adjuvant therapy with antibiotics has yielded highly variable outcomes. Multivalent polymeric materials offer an alternative approach to bind and sequester i ...
DOI:: 10.1021/bm5016392
: https://doi.org/10.1021/bm5016392

62. Antibiotic Efficacy and Characterization of Mangrove Metabolites against UTI Microbes

Author:: Meivelu Moovendhan; R. Ramasubburayan; S. Vairamani; A. Shanmugam; A. Palavesam; G. Immanuel
Source:: Journal of herbs, spices & medicinal plants 2015 v.21 no.2 pp. 129-139
ISSN:: 1540-3580
Subject:: Avicennia marina; Rhizophora mucronata; alkaloids; antibacterial properties; antibiotics; fractionation; herbs; hydrogen bonding; leaves; medicinal plants; metabolites; microorganisms; minimum inhibitory concentration; phytochemicals; spices; urinary tract
Abstract:: ... In vitro antibacterial aptitude of Avicennia marina, A. marina var acutissima, Rhizophora mucronata , and R. annamalayana leaves were evaluated for urinary tract infective bacterial strains. A. marina var. acutissima and R. annamalayana methanolic extracts had diverse phytochemicals and demonstrated lower antibacterial activity at the concentrations of 100 to 250 μg.mL ⁻¹ and greater activity at 5 ...
DOI:: 10.1080/10496475.2014.923357
: https://doi.org/10.1080/10496475.2014.923357

63. Antibiotic Residue Monitoring Results for Pork, Chicken, and Beef Samples in Vietnam in 2012-2013

Author:: Takahiro Yamaguchi; Masahiro Okihashi; Kazuo Harada; Yoshimasa Konishi; Kotaro Uchida; Do Mai Hoang Ngoc; Bui Huong Dang Thien; Nguyen Thinh Duc; Nguyen Phuc Do; Chau Vien Van; Dao Khanh Thi Van; Nguyen Hue Thi Ngoc; Keiji Kajimura; Yuko Kumeda; Bui Chien Trong; Vien Mai Quang; Le Ninh Hoang; Kazumasa Hirata; Yoshimasa Yamamoto
Source:: Journal of agricultural and food chemistry 2015 v.63 no.21 pp. 5141-5145
ISSN:: 0021-8561
Subject:: animal-based foods; antibiotic residues; antibiotics; beef; chickens; fluoroquinolones; monitoring; pork; screening; slaughterhouses; sulfonamides; Vietnam
Abstract:: ... A monitoring plan of residual antibiotics in food of animal origin was conducted in Vietnam from 2012 to 2013. Meat samples were collected from slaughterhouses and retail stores in Ho Chi Minh City and Nha Trang. A total of 28 antibiotics were analyzed using a LC-MS/MS screening method. Sulfonamides, fluoroquinolones, and tilmicosin were detected in some of the samples. Sulfaclozine and fluoroquin ...
DOI:: 10.1021/jf505254y
: https://doi.org/10.1021/jf505254y

64. Antibiotic Resistance Versus Antimicrobial Substances Production by Gram-Negative Foodborne Pathogens Isolated from Minas Frescal Cheese: Heads or Tails?

Author:: Damaceno Hugo Figueiredo Botelho; de Freitas Junior Claudinei Vieira; Marinho Iuri Lourenço; Cupertino Thomaz Rocha; Costa Leonardo Emanuel de Oliveira; Nascimento Janaína dos Santos
Source:: Foodborne pathogens & disease 2015 v.12 no.4 pp. 297-301
ISSN:: 1556-7125
Subject:: Acinetobacter; Enterobacter; Escherichia coli; Gram-negative bacteria; Hafnia; Salmonella; Yersinia; antibiotic resistance; antibiotics; cheeses; food industry; food pathogens; plasmids; Brazil
Abstract:: ... In this study, 15 Gram-negative isolates from Minas Frescal cheese sold in commercial establishments in Rio de Janeiro, Brazil, were able to produce antimicrobial substances (AMSs). Seven, four, two, one, and one isolates identified as Yersinia, Acinetobacter, Enterobacter, Escherichia, and Hafnia genera, respectively, were considered potentially pathogenic. All 15 AMS⁺ isolates were resistant to ...
DOI:: 10.1089/fpd.2014.1876
: https://doi.org/10.1089/fpd.2014.1876

65. Antibiotic Resistome and Its Association with Bacterial Communities during Sewage Sludge Composting

Author:: Su Jian-Qiang; Wei Bei; Ou-Yang Wei-Ying; Huang Fu-Yi; Zhao Yi; Xu Hui-Juan; Zhu Yong-Guan
Source:: Environmental Science & Technology 2015 v.49 no.12 pp. 7356-7363
ISSN:: 1520-5851
Subject:: Actinobacteria; antibiotic resistance; antibiotics; bacteria; bacterial communities; community structure; composting; genes; interspersed repetitive sequences; phylogeny; quantitative polymerase chain reaction; recycling; ribosomal RNA; sewage sludge; soil properties
Abstract:: ... Composting is widely used for recycling of urban sewage sludge to improve soil properties, which represents a potential pathway of spreading antibiotic resistant bacteria and genes to soils. However, the dynamics of antibiotic resistance genes (ARGs) and the underlying mechanisms during sewage sludge composting were not fully explored. Here, we used high-throughput quantitative PCR and 16S rRNA ge ...
DOI:: 10.1021/acs.est.5b01012
: https://doi.org/10.1021/acs.est.5b01012

66. Antibiotic Suppression of Intestinal Microbiota Reduces Heme-Induced Lipoperoxidation Associated with Colon Carcinogenesis in Rats

Author:: O. C. B. Martin; C. Lin; N. Naud; S. Tache; I. Raymond-Letron; D. E. Corpet; F. H. Pierre
Source:: Nutrition and cancer 2015 v.67 no.1 pp. 119-125
ISSN:: 1532-7914
Subject:: agar; antibiotics; bacteria; biomarkers; carcinogenesis; colon; colorectal neoplasms; diet; epidemiological studies; heme; heme iron; hemoglobin; intestinal microorganisms; peroxidation; rats; red meat; risk; thiobarbituric acid
Abstract:: ... Epidemiological studies show that heme iron from red meat is associated with increased colorectal cancer risk. In carcinogen-induced-rats, a heme iron-rich diet increases the number of precancerous lesions and raises associated fecal biomarkers. Heme-induced lipoperoxidation measured by fecal thiobarbituric acid reagents (TBARs) could explain the promotion of colon carcinogenesis by heme. Using a ...
DOI:: 10.1080/01635581.2015.976317
: https://doi.org/10.1080/01635581.2015.976317

67. Antibiotic Susceptibility and Functional Group Characterization of Pinna nobilis Metabolites Against Clinical Isolates

Author:: Meivelu Moovendhan; Palaniappan Seedevi; Annaian Shanmugam; Vairamani Shanmugam
Source:: Journal of Biologically Active Products from Nature 2015 v.5 no.1 pp. 52-57
ISSN:: 2231-1874
Subject:: Aeromonas; Escherichia coli; Pinna nobilis; Staphylococcus aureus; Vibrio; alcohols; alkynes; amines; antibacterial properties; antibiotic resistance; antibiotics; calcium; drugs; ethers; hydrogen bonding; metabolites; minimum inhibitory concentration; nitriles; nitrogen dioxide
Abstract:: ... The present study was conducted to extraction and evaluation of antimicrobial potential and functional groups characterization of Pinna nobilis extract against clinical isolates such as Escherichia coli, Staphylococcus aureus, Bacilus subtilis, Vibrio Harvey and Aeromonas hydrophilla. The better antimicrobial activity results showed 10 to 12 mm at 750 µg/ml against E. coli, V. harvey and A. hydrop ...
DOI:: 10.1080/22311866.2014.983975
: https://doi.org/10.1080/22311866.2014.983975

68. Antibiotic efficacy is linked to bacterial cellular respiration

Author:: Michael A. Lobritz; Peter Belenky; Caroline B. M. Porter; Arnaud Gutierrez; Jason H. Yang; Eric G. Schwarz; Daniel J. Dwyer; Ahmad S. Khalil; James J. Collins
Source:: Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.27 pp. 8173-8180
ISSN:: 0027-8424
Subject:: adenosine triphosphate; antibacterial properties; antibiotics; bacteria; cell death; cell respiration; drugs; electron transfer; electron transport chain; energy; growth retardation; metabolites; metabolomics; microbial growth; phenotype
Abstract:: ... Bacteriostatic and bactericidal antibiotic treatments result in two fundamentally different phenotypic outcomes—the inhibition of bacterial growth or, alternatively, cell death. Most antibiotics inhibit processes that are major consumers of cellular energy output, suggesting that antibiotic treatment may have important downstream consequences on bacterial metabolism. We hypothesized that the speci ...
DOI:: 10.1073/pnas.1509743112
PubMed:: 26100898
PubMed Central:: PMC4500273
: https://doi.org/10.1073/pnas.1509743112

69. Antibiotic overuse and Clostridium difficile infections: The Indian paradox and the possible role of dietary practices

Author:: N. Ramakrishnan; K. Sriram
Source:: Nutrition 2015 v.31 no.7-8 pp. 1052-1053
ISSN:: 0899-9007
Subject:: Clostridium difficile; antibiotics; diet; polymerase chain reaction; protective effect; turmeric; yogurt; India; United States
Abstract:: ... Antibiotic abuse is rampant in India, such that one may expect to see an increase of Clostridium difficile infections (CDI). However, we found that the incidence of CDI in India (1.67%) is no different from that reported in USA (1.6%) using similar techniques of detection (polymerase chain reaction test). We offer a possible explanation for this paradox. It is likely that a diet rich in fiber, yog ...
DOI:: 10.1016/j.nut.2015.02.002
: https://doi.org/10.1016/j.nut.2015.02.002

70. Antibiotic oxylipins from Alternanthera brasiliana and its endophytic bacteria

Author:: Marília Almeida Trapp; Marco Kai; Axel Mithöfer; Edson Rodrigues-Filho
Source:: Phytochemistry 2015 v.110 pp. 72-82
ISSN:: 0031-9422
Subject:: Alternanthera; animal pathogenic bacteria; antibiotics; endophytes; fractionation; nuclear magnetic resonance spectroscopy; oxylipins; tissues
Abstract:: ... Bioassay-guided fractionation of Alternanthera brasiliana stem extracts resulted in the isolation of an antibiotically active fraction. Five human pathogenic bacteria were used to guide the fractionation process for the isolation of antimicrobial compounds. Finally, 17 linoleate oxylipins were identified by LC–MS/MS and NMR spectroscopy. Five of the isolated compounds present in A. brasiliana tiss ...
DOI:: 10.1016/j.phytochem.2014.11.005
: https://doi.org/10.1016/j.phytochem.2014.11.005

71. Antibiotic resistance modulation by natural products obtained from Nasutitermes corniger (Motschulsky, 1855) and its nest

Author:: Thiago P. Chaves; Elaine L.C. Clementino; Delcio C. Felismino; Rômulo R.N. Alves; Alexandre Vasconcellos; Henrique D.M. Coutinho; Ana Cláudia D. Medeiros
Source:: Saudi Journal of Biological Sciences 2015 v.22 pp. 404-408
ISSN:: 1319-562X
Subject:: Escherichia coli; Nasutitermes; Staphylococcus aureus; antibiotic resistance; antibiotics; antimicrobial properties; drug therapy; ethanol; insects; minimum inhibitory concentration; nationalities and ethnic groups; nests; semiarid zones
Abstract:: ... Insects and their products are included in the traditional pharmacopoeia of various ethnic groups worldwide. In the Brazilian semiarid region can be highlighted the use of the termite Nasutitermes corniger for the treatment of various diseases. This study evaluated the ethanol extract of N. corniger and its nest as an antimicrobial agent and as a modulator of bacterial resistance against multidrug ...
DOI:: 10.1016/j.sjbs.2014.12.005
PubMed:: 26150745
PubMed Central:: PMC4486467
: https://doi.org/10.1016/j.sjbs.2014.12.005

72. Antibiotic resistance patterns and PCR-ribotyping of Clostridium difficile strains isolated from swine and dogs in Italy

Author:: Patrizia Spigaglia; Ilenia Drigo; Fabrizio Barbanti; Paola Mastrantonio; Luca Bano; Cosetta Bacchin; Cinzia Puiatti; Elena Tonon; Giacomo Berto; Fabrizio Agnoletti
Source:: Anaerobe 2015 v.31 pp. 42-46
ISSN:: 1075-9964
Subject:: Clostridium difficile; agar; antibiotic resistance; antibiotics; dogs; farms; humans; pets; phenotype; risk; swine; virulent strains; Italy
Abstract:: ... Recent studies suggest animals, in particular farm and companion animals, as possible reservoir for Clostridium difficile human pathogenic strains. The aim of this study was to give a first characterization of C. difficile isolates from Italian swine and dogs. In total, 10 different PCR-ribotypes were identified among porcine strains and six among canine strains. The predominant type found among p ...
DOI:: 10.1016/j.anaerobe.2014.10.003
: https://doi.org/10.1016/j.anaerobe.2014.10.003

73. Antibiotic resistance: An ethical challenge

Author:: Jasper Littmann; Alena Buyx; Otto Cars
Source:: International journal of antimicrobial agents 2015 v.46 no.4 pp. 359-361
ISSN:: 0924-8579
Subject:: animal welfare; antibiotic resistance; antibiotics; disease control; ethics; farming systems; infectious diseases; issues and policy; multiple drug resistance; sustainable agriculture; veterinary medicine
Abstract:: ... In this paper, we argue that antibiotic resistance (ABR) raises a number of ethical problems that have not yet been sufficiently addressed. We outline four areas in which ethical issues that arise in relation to ABR are particularly pressing. First, the emergence of multidrug-resistant and extensively drug-resistant infections exacerbates traditional ethical challenges of infectious disease contro ...
DOI:: 10.1016/j.ijantimicag.2015.06.010
: https://doi.org/10.1016/j.ijantimicag.2015.06.010

74. Antibiotic-Induced Depletion of Murine Microbiota Induces Mild Inflammation and Changes in Toll-Like Receptor Patterns and Intestinal Motility

Author:: Laura Grasa; Leticia Abecia; Raquel Forcén; Marta Castro; José Antonio García de Jalón; Eva Latorre; Ana Isabel Alcalde; María Divina Murillo
Source:: Microbial ecology 2015 v.70 no.3 pp. 835-848
ISSN:: 0095-3628
Subject:: Toll-like receptor 2; Toll-like receptor 3; Toll-like receptor 4; Toll-like receptor 5; Toll-like receptor 6; Toll-like receptor 7; Toll-like receptor 8; Toll-like receptor 9; acetylcholine; antibiotics; cecum; colon; denaturing gradient gel electrophoresis; flagellin; gastrointestinal motility; ileum; inflammation; intestinal microorganisms; lipopolysaccharides; mice; muscle strength
Abstract:: ... We examine the impact of changes in microbiota induced by antibiotics on intestinal motility, gut inflammatory response, and the function and expression of toll-like receptors (TLRs). Alterations in mice intestinal microbiota were induced by antibiotics and evaluated by q-PCR and DGGE analysis. Macroscopic and microscopic assessments of the intestine were performed in control and antibiotic-treate ...
DOI:: 10.1007/s00248-015-0613-8
: https://doi.org/10.1007/s00248-015-0613-8

75. Antibiotic-Resistant Bacteria: Prevalence in Food and Inactivation by Food-Compatible Compounds and Plant Extracts

Author:: Mendel Friedman
Source:: Journal of agricultural and food chemistry 2015 v.63 no.15 pp. 3805-3822
ISSN:: 0021-8561
Subject:: Bacillus cereus; Campylobacter jejuni; Clostridium perfringens; Escherichia coli; Salmonella enterica; Staphylococcus aureus; Vibrio cholerae; Vibrio parahaemolyticus; adverse effects; animal pathogens; anti-infective properties; antibiotic resistance; antibiotics; bacteria; chlorine; eggs; feeds; food chain; food safety; heat; human diseases; humans; meat; pathogenesis; plant extracts; poultry; pulsed electric fields; seafoods; surveys; ultraviolet radiation
Abstract:: ... Foodborne antibiotic-resistant pathogenic bacteria such as Campylobacter jejuni, Bacillus cereus, Clostridium perfringens, Escherichia coli, Salmonella enterica, Staphylococcus aureus, Vibrio cholerae, and Vibrio parahemolyticus can adversely affect animal and human health, but a better understanding of the factors involved in their pathogenesis is needed. To help meet this need, this overview sur ...
DOI:: 10.1021/acs.jafc.5b00778
: https://doi.org/10.1021/acs.jafc.5b00778

76. Antibiotic-induced imbalances in gut microbiota aggravates cholesterol accumulation and liver injuries in rats fed a high-cholesterol diet

Author:: Xu Hu; Tao Wang; Shan Liang; Wei Li; Xiaoli Wu; Feng Jin
Source:: Applied microbiology and biotechnology 2015 v.99 no.21 pp. 9111-9122
ISSN:: 0175-7598
Subject:: Firmicutes; Proteobacteria; Toll-like receptor 4; absorption; antibiotics; chemokines; cholesterol; diet; homeostasis; human health; intestinal microorganisms; lipopolysaccharides; liver; liver diseases; metabolic diseases; microbial communities; permeability; rats; tissues
Abstract:: ... Increasing evidence suggests that maintenance of homeostasis between gut microbiota and host plays an important role in human health. Many diseases, such as those affecting the liver, have been linked to imbalances in gut microbial communities. However, it is not clear whether an imbalance in gut microbiota promotes the onset of liver injury or if the imbalance results from the pathological state. ...
DOI:: 10.1007/s00253-015-6753-4
: https://doi.org/10.1007/s00253-015-6753-4

77. Antibiotics and the developing infant gut microbiota and resistome

Author:: Molly K Gibson; Terence S Crofts; Gautam Dantas
Source:: Current opinion in microbiology 2015 v.27 pp. 51-56
ISSN:: 1369-5274
Subject:: adults; antibiotic resistance genes; antibiotics; community structure; diet; digestive system; genotype; human health; humans; infectious diseases; intestinal microorganisms; microbial communities
Abstract:: ... The microbial communities colonizing the human gut are tremendously diverse and highly personal. The composition and function of the microbiota play important roles in human health and disease, and considerable research has focused on understanding the ecological forces shaping these communities. While it is clear that factors such as diet, genotype of the host, and environment influence the adult ...
DOI:: 10.1016/j.mib.2015.07.007
PubMed:: 26241507
PubMed Central:: PMC4659777
: https://doi.org/10.1016/j.mib.2015.07.007

78. Anticorrosion/antifouling properties of bacterial spore-loaded sol–gel type coating for mild steel in saline marine condition: a case of thermophilic strain of Bacillus licheniformis

Author:: Ubong Eduok; Rami Suleiman; Jeanette Gittens; Mazen Khaled; Thomas J. Smith; Robert Akid; Bassam El Ali; Amjad Khalil
Source:: RSC advances 2015 v.5 no.114 pp. 93818-93830
ISSN:: 2046-2069
Subject:: Bacillus licheniformis; antibiotics; antifouling activities; biofilm; capacitance; coatings; corrosion; electrochemistry; electron microscopy; encapsulation; endospores; fluorescence; fluorescence microscopy; fouling; hydrophobicity; inoculum; ions; molybdates; pigments; sodium chloride; steel; viability; Persian Gulf; Saudi Arabia
Abstract:: ... This work reports the performance of a sol–gel type coating encapsulated with biofilm of inoculums of protective thermophilic strain of Bacillus licheniformis endospores isolated from the Gazan hot springs-Saudi Arabia for the inhibition of marine fouling and corrosion protection of S36-grade mild steel in 3.5 wt% NaCl medium. In order to improve its anticorrosion properties, the hybrid sol–gel co ...
DOI:: 10.1039/c5ra16494j
: https://doi.org/10.1039/c5ra16494j

79. Antidiabetic and Antilipidemic Effects of Manilkara zapota

Author:: Barbalho Sandra Maria; Bueno Patrícia Cincotto dos Santos; Delazari Débora Souza; Guiguer Elen Landgraf; Coqueiro Daniel Pereira; Araújo Adriano Cressoni; de Souza Maricelma da Silva Soares; Farinazzi-Machado Flávia M.V.; Mendes Claudemir Gregório; Groppo Milton
Source:: Journal of medicinal food 2015 v.18 no.3 pp. 385-391
ISSN:: 1557-7600
Subject:: Manilkara zapota; alanine transaminase; alternative medicine; antibiotics; aspartate transaminase; blood glucose; body composition; body mass index; cholesteremic effect; common cold; diabetes; fruit juices; fruit pulp; glycemic effect; high density lipoprotein cholesterol; hyperlipidemia; insulin; leaves; leptin; males; metabolic studies; obesity; rats; trees; triacylglycerols; weight gain
Abstract:: ... Manilkara zapota is a tropical evergreen tree belonging to the Sapotaceae family; its parts are used in alternative medicine to treat coughs and colds and possess diuretic, antidiarrheal, antibiotic, antihyperglycemic, and hypocholesterolemic effects. There are no studies on metabolic profile after using the fruit, and this study aimed at evaluating the effects of the leaf and pulp of M. zapota fr ...
DOI:: 10.1089/jmf.2013.0170
: https://doi.org/10.1089/jmf.2013.0170

80. Antimalarial and antimycobacterial agents from Streptomyces sp. BCC27095

Author:: Chakapong Intaraudom; Nantiya Bunbamrung; Aibrohim Dramae; Kannawat Danwisetkanjana; Pranee Rachtawee; Pattama Pittayakhajonwut
Source:: Tetrahedron letters 2015 v.56 no.49 pp. 6875-6877
ISSN:: 0040-4039
Subject:: Bacillus cereus; Mycobacterium tuberculosis; Plasmodium falciparum; Streptomyces; anthraquinones; antibacterial properties; antibiotics; antimalarials; chemical reactions; chemical structure; cytotoxicity; inhibitory concentration 50; multiple drug resistance; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:: ... Investigation of the terrestrial Streptomyces sp. BCC27095 led to the isolation of two new (1 and 2) and two known (3 and 5) anthraquinone derivatives along with the previously reported compound, steffimycin B (4). The chemical structures were determined on the basis of NMR spectroscopic data. These compounds exhibited significant antimalarial (against Plasmodium falciparum, K-1 multidrug resistan ...
DOI:: 10.1016/j.tetlet.2015.10.098
: https://doi.org/10.1016/j.tetlet.2015.10.098

81. Antimicrobial Activity and Composition of Essential Oil from Echinophora platyloba

Author:: Nasrin Fayyaz; Ali Mohamadi Sani; Masoud Najaf Najafi
Source:: Journal of essential oil-bearing plants 2015 v.18 no.5 pp. 1157-1164
ISSN:: 0976-5026
Subject:: Aspergillus niger; Bacillus subtilis; Escherichia coli O157; Listeria monocytogenes; Staphylococcus aureus; anti-infective properties; antibiotics; bacteria; chemical composition; essential oils; eugenol; fungi; gas chromatography-mass spectrometry; hydrodistillation; isomers; minimum inhibitory concentration; oils; paper; styrene
Abstract:: ... The antimicrobial activity of essential oils and their derivatives has been recognized for a long time. In this study, the chemical composition and antimicrobial activity of Echinophora platyloba essential oil against Escherichia coli O157, Staphylococcus aureus, Bacillus subtilis, Listeria monocytogenes and Aspergillus niger . The essential oil obtained by hydro-distillation extraction method usi ...
DOI:: 10.1080/0972060X.2014.971064
: https://doi.org/10.1080/0972060X.2014.971064

82. Antimicrobial Activity of Gold Nanoparticles and Ionic Gold

Author:: Ying Zhang; Thabitha P. Shareena Dasari; Hua Deng; Hongtao Yu
Source:: Journal of environmental science and health 2015 v.33 no.3 pp. 286-327
ISSN:: 1532-4095
Subject:: antibacterial properties; antibiotics; coatings; gold; ions; nanogold; nanoparticles
Abstract:: ... Gold, in both nanoparticle (AuNPs) and ionic forms, has been studied for antibiotic activities. Some of the organic complexes of Au (I & III) ions are antibacterial. AuNPs are antifungal, but with conflicting results on their antibacterial activity. We summarized these publications and found that AuNPs are generally not bactericidal, or only weakly at high concentrations. However, the reason AuNPs ...
DOI:: 10.1080/10590501.2015.1055161
: https://doi.org/10.1080/10590501.2015.1055161

83. The Antimicrobial Activity of an Acidic Phospholipase A2 (NN-XIa-PLA2) from the Venom of Naja naja naja (Indian Cobra)

Author:: S. Sudarshan; B. L. Dhananjaya
Source:: Applied biochemistry and biotechnology 2015 v.176 no.7 pp. 2027-2038
ISSN:: 0273-2289
Subject:: Gram-negative bacteria; Gram-positive bacteria; Naja naja; antibacterial properties; antibiotics; bacterial infections; catalytic activity; enzyme activity; humans; mechanism of action; minimum inhibitory concentration; phospholipase A2; public health; venoms; virulent strains
Abstract:: ... Microbial resistance against antibiotics is considered as a potentially serious threat to public health. Therefore, there is much interest in developing new molecules with novel modes of action. In this study, when antimicrobial potential of an acidic protein—NN-XIa-PLA₂ (Naja naja venom phospholipase A₂ fraction—XIa) of N. naja venom was evaluated, it demonstrated potent bactericidal action again ...
DOI:: 10.1007/s12010-015-1698-8
: https://doi.org/10.1007/s12010-015-1698-8

84. Antimicrobial Properties of Cocos nucifera: A Review

Author:: Lalitha Ramaswamy
Source:: CORD. Coconut research & development 2015 v.31 no.01 pp. 1-6
ISSN:: 2721-8856
Subject:: Allium cepa; Candida; Food and Agriculture Organization; National Health and Nutrition Examination Survey; Raja; Rosa; acne; alternative medicine; antibacterial properties; antibiotics; antifungal properties; antileishmanial properties; antimicrobial peptides; antioxidant activity; antioxidants; biofilm; chemical constituents of plants; chloramphenicol; coconut meal; coconut oil; coconut water; coconuts; databases; disease prevention; dodecanoic acid; endocarp; fermentation; flour; flowers; gastrointestinal system; health promotion; hexane; hulls; medicinal plants; mesocarp; monoacylglycerols; nutrient intake; onions; paper; phytochemicals; polyphenols; probiotics; research; sheep; toxicity; traditional medicine; trees; India; Nigeria
Abstract:: ... Akinyele, T.A., 2011. Assessment of the antibacterial properties of n-Hexane extract of Cocos Nucifera and its interactions with some Conventional antibiotics. Masters Dissertation. University of Fort Hare, Alice. Alan´ıs, A.D., Calzada, F, Cervantes J.A., Torres, J., and Ceballos, G.M. 2005. Antibacterial properties of some plants used in Mexican traditional medicine for the treatment of gastroin ...
DOI:: https://doi.org/10.37833/cord.v31i1.62
: https://doi.org/https://doi.org/10.37833/cord.v31i1.62

85. Antimicrobial activities of endophytic fungi obtained from the arid zone invasive plant Opuntia dillenii and the isolation of equisetin, from endophytic Fusarium sp.

Author:: Pamoda B. Ratnaweera; E. Dilip de Silva; David E. Williams; Raymond J. Andersen
Source:: BMC complementary and alternative medicine 2015 v.15 no.1 pp. 220
ISSN:: 1472-6882
Subject:: Aspergillus niger; Bacillus subtilis; Candida albicans; DNA; Fusarium; Opuntia stricta var. dillenii; abiotic stress; active ingredients; alternative medicine; antibiotics; arid zones; bioassays; chemical structure; chromatography; cladodes; endophytes; fungi; invasive species; methicillin-resistant Staphylococcus aureus; niches; secondary metabolites; spectral analysis; Sri Lanka
Abstract:: ... BACKGROUND: Opuntia dillenii is an invasive plant well established in the harsh South-Eastern arid zone of Sri Lanka. Evidence suggests it is likely that the endophytic fungal populations of O. dillenii assist the host in overcoming biotic and abiotic stress by producing biologically active metabolites. With this in mind there is potential to discover novel natural products with useful biological ...
DOI:: 10.1186/s12906-015-0722-4
: https://doi.org/10.1186/s12906-015-0722-4

86. Antimicrobial activities of selected essential oils against Fusarium oxysporum isolates and their biofilms

Author:: M.C. Manganyi; T. Regnier; E.I. Olivier
Source:: South African journal of botany 2015 v.99 pp. 115-121
ISSN:: 0254-6299
Subject:: Fusarium oxysporum; antibiotics; antifungal properties; biofilm; citral; cleaning; cloves; confocal laser scanning microscopy; cornea; essential oils; eugenol; fungi; in vitro studies; keratitis; oils; screening; storage conditions; thyme; thymol; toxicity
Abstract:: ... Fusarium infections, such as keratitis, are becoming increasingly difficult to control due to the build-up of resistance of fungi towards conventional antibiotics. Resistance is further enhanced by their ability to form fungal biofilms. Poor storage conditions and inadequate cleaning of contact lenses often lead to corneal infections. The solution to problems associated with contamination and resi ...
DOI:: 10.1016/j.sajb.2015.03.192
: https://doi.org/10.1016/j.sajb.2015.03.192

87. Antimicrobial activity of Ficus sycomorus L. (Moraceae) leaf and stem-bark extracts against multidrug resistant human pathogens

Author:: Basel Saleh; Razan Hammoud; Ayman Al-Mariri
Source:: Herba Polonica 2015 v.61 no.1 pp. 39-49
ISSN:: 0018-0599
Subject:: Acinetobacter baumannii; Ficus sycomorus; Staphylococcus aureus; acetone; animal pathogens; antibacterial properties; antibiotics; bacteria; bark; drugs; leaf extracts; leaves; methanol; minimum inhibitory concentration; multiple drug resistance
Abstract:: ... The present work was conducted to investigate antibacterial activity of methanol and acetone in leaf (LE) and stem-bark (SBE) of Ficus sycomorus L. crude extracts against sensitive and resistant species of Staphylococcus aureus and Acinetobacter baumannii pathogens. Antimicrobial activity expressed by disc-diffusion method (zone of inhibitions - ZIs), minimum inhibitory concentrations (MICs) and m ...
DOI:: 10.1515/hepo-2015-0009
: https://doi.org/10.1515/hepo-2015-0009

88. Antimicrobial delivery systems for local infection prophylaxis in orthopedic- and trauma surgery

Author:: Gert-Jan A. ter Boo; Dirk W. Grijpma; Thomas F. Moriarty; Robert G. Richards; David Eglin
Source:: Biomaterials 2015 v.52 pp. 113-125
ISSN:: 0142-9612
Subject:: antibiotic resistance; antibiotics; antimicrobial peptides; biocompatible materials; biofilm; disease control; fracture fixation; health status; pathogens; patients; risk; silver; tissues; toxicity
Abstract:: ... Infectious complications occur in a minor but significant portion of the patients undergoing joint replacement surgery or fracture fixation, particularly those with severe open fractures, those undergoing revision arthroplasty or those at elevated risk because of poor health status. Once established, infections are difficult to eradicate, especially in the case of bacterial biofilm formation on im ...
DOI:: 10.1016/j.biomaterials.2015.02.020
: https://doi.org/10.1016/j.biomaterials.2015.02.020

89. Antimicrobial effects of modified chitosan based coating containing nanoemulsion of essential oils, modified atmosphere packaging and gamma irradiation against Escherichia coli O157:H7 and Salmonella Typhimurium on green beans

Author:: Renato Severino; Giovanna Ferrari; Khanh Dang Vu; Francesco Donsì; Stéphane Salmieri; Monique Lacroix
Source:: Food control 2015 v.50 pp. 215-222
ISSN:: 0956-7135
Subject:: Escherichia coli O157; Salmonella Typhimurium; antibacterial properties; antibiotics; bacteria; carvacrol; chitosan; coatings; culture media; essential oils; food industry; food safety; gamma radiation; green beans; in vitro studies; lemons; mandarins; minimum inhibitory concentration; modified atmosphere packaging; nanoemulsions; shelf life; storage time; synergism
Abstract:: ... The antibacterial activity of modified chitosan-based coatings containing nanoemulsion of essential oils (EOs), gamma irradiation, modified atmosphere packaging (MAP), alone or in combinations, against Escherichia coli O157:H7 and Salmonella Typhimurium was evaluated on inoculated green bean samples. Firstly, four different nanoemulsions, made of carvacrol, mandarin, bergamot and lemon Eos, respec ...
DOI:: 10.1016/j.foodcont.2014.08.029
: https://doi.org/10.1016/j.foodcont.2014.08.029

90. Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution

Author:: Tobias Bollenbach
Source:: Current opinion in microbiology 2015 v.27 pp. 1-9
ISSN:: 1369-5274
Subject:: antibiotics; cell physiology; combination drug therapy; drug interactions; drugs; evolution; prediction
Abstract:: ... Combining antibiotics is a promising strategy for increasing treatment efficacy and for controlling resistance evolution. When drugs are combined, their effects on cells may be amplified or weakened, that is the drugs may show synergistic or antagonistic interactions. Recent work revealed the underlying mechanisms of such drug interactions by elucidating the drugs’ joint effects on cell physiology ...
DOI:: 10.1016/j.mib.2015.05.008
: https://doi.org/10.1016/j.mib.2015.05.008

91. Antimicrobial peptides: Possible anti-infective agents

Author:: Jayaram Lakshmaiah Narayana; Jyh-Yih Chen
Source:: Peptides 2015 v.72 pp. 88-94
ISSN:: 0196-9781
Subject:: antibiotics; antimicrobial peptides; bacteria; business enterprises; developmental stages; fungi; health services; immunomodulators; multiple drug resistance; parasites; parasitoses; pathogens; pharmaceutical industry; viruses
Abstract:: ... Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats. The Infectious Diseases Society of America has expressed concern on the decrease of pharmaceutical companies working on antibiotic research and development. However, small companies, along with academic research institutes, are stepping forward to develop novel therapeutic methods to overcome the prese ...
DOI:: 10.1016/j.peptides.2015.05.012
: https://doi.org/10.1016/j.peptides.2015.05.012

92. Antimicrobial photodynamic therapy using chlorin e6 with halogen light for acne bacteria-induced inflammation

Author:: Yu-Mi Jeon; Hwan-Suk Lee; Dongjun Jeong; Hae-Keun Oh; Kyu-Hwan Ra; Mi-Young Lee
Source:: Life sciences 2015 v.124 pp. 56-63
ISSN:: 0024-3205
Subject:: Propionibacterium acnes; Spirulina; acne; anti-inflammatory activity; antibiotics; antimicrobial properties; bacteria; chlorins; chlorophyll; cytokines; dose response; ears; fluorescence; free radicals; halogens; histology; inducible nitric oxide synthase; inflammation; mice; minimum inhibitory concentration; photochemotherapy; photosensitizing agents; prostaglandin synthase
Abstract:: ... The present study was designed to evaluate the therapeutic potential of antimicrobial photodynamic therapy (PDT) using chlorin e6 with halogen light against acne bacteria-induced inflammation.Highly purified chlorin e6 (Ce6), as a second generation photosensitizer, was synthesized from Spirulina chlorophyll. To evaluate the antimicrobial property of Ce6-mediated PDT with halogen light, the broth m ...
DOI:: 10.1016/j.lfs.2014.12.029
: https://doi.org/10.1016/j.lfs.2014.12.029

93. Antioxidant and antitumour activities of extracts from Patrinia villosa and its active constituents

Author:: Jia-Chuan Lei; Cheng-Xiong Yang; Yuan Yang; Wu Zhang; Jian-Qing Yu
Source:: Journal of functional foods 2015 v.16 pp. 289-294
ISSN:: 1756-4646
Subject:: 4-hydroxybenzoic acid; Patrinia villosa; active ingredients; antibiotics; antineoplastic activity; antioxidant activity; antioxidants; chromatography; chronic diseases; cytotoxicity; ethanol; ethyl acetate; functional foods; leaves; medicinal plants; neoplasms; plant extracts; risk; ursolic acid; vegetables; China
Abstract:: ... Patrinia villosa Juss is a famous medicinal herb and is used as an anti-inflammatory and anti-bacterial agent. Its tender leaves have also been used as a wild vegetable in China. In this study, the antioxidant and cytotoxic activities of various fractions of ethanol extract from P. villosa were investigated, the ethyl acetate fraction (EE-PV) exhibited the strongest antioxidant activity and cytoto ...
DOI:: 10.1016/j.jff.2015.04.037
: https://doi.org/10.1016/j.jff.2015.04.037

94. Antioxidative responses of Pseudomonas fluorescens YZ2 to simultaneous exposure of Zn and Cefradine

Author:: Yan-Bin Xu; Jia-Xin Xu; Jin-Liang Chen; Lu Huang; Shao-Qi Zhou; Yan Zhou; Li-Hua Wen
Source:: Ecotoxicology 2015 v.24 no.7-8 pp. 1788-1797
ISSN:: 0963-9292
Subject:: determinate growth; risk; protein synthesis; Pseudomonas fluorescens; humans; antibiotics; zinc; heavy metals; reactive oxygen species; superoxide dismutase; environmental health; pollutants; health hazards; microbial growth; oxidants; toxicity; wastewater; bacteria; swine
Abstract:: ... Binary pollution of both heavy metals and antibiotics has received increasing attentions for their joint effects of eco-toxicity and health hazards. To reveal the effects of mixtures of different pollutants on bacterial antioxidant response system, Pseudomonas fluorescens ZY2, a new strain isolated from swine wastewater, was chosen to determinate growth (bacterial density OD₆₀₀), reactive oxygen s ...
DOI:: 10.1007/s10646-015-1516-7
: https://doi.org/10.1007/s10646-015-1516-7

95. Anti‐inflammatory activities of cecropin a and its mechanism of action

Author:: Eunjung Lee; Areum Shin; Yangmee Kim
Source:: Archives of insect biochemistry and physiology 2015 v.88 no.1 pp. 31-44
ISSN:: 0739-4462
Subject:: Hyalophora cecropia; anti-infective properties; anti-inflammatory activity; antibiotics; antimicrobial peptides; bacteria; cytokines; lipopolysaccharides; mechanism of action; mice; mitogen-activated protein kinase; multiple drug resistance; nitrites; phospholipids; tryptophan
Abstract:: ... Cecropin A is a novel 37‐residue cecropin‐like antimicrobial peptide isolated from the cecropia moth, Hyalophora cecropia. We have demonstrated that cecropin A is an antibacterial agent and have investigated its mode of action. In this study, we show that cecropin A has potent antimicrobial activity against 2 multidrug resistant organisms—Acinetobacter baumanii and—Pseudomonas aeruginosa. Interact ...
DOI:: 10.1002/arch.21193
: https://doi.org/10.1002/arch.21193

96. Application of 3D NMR for Structure Determination of Peptide Natural Products

Author:: Zhang Fan; Adnani Navid; Vazquez-Rivera Emmanuel; Braun Doug R.; Tonelli Marco; Andes David R.; Bugni Tim S.
Source:: Journal of organic chemistry 2015 v.80 no.17 pp. 8713-8719
ISSN:: 1520-6904
Subject:: antibiotics; chemical reactions; chemical structure; cost effectiveness; nuclear magnetic resonance spectroscopy; organic chemistry; organic compounds
Abstract:: ... Despite the advances in NMR, structure determination is often slow and constitutes a bottleneck in natural products discovery. Removal of this bottleneck would greatly improve the throughput for antibiotic discovery as well as other therapeutic areas. Overall, faster structure methods for structure determination will serve the natural products community in a broad manner. This report describes the ...
DOI:: 10.1021/acs.joc.5b01486
PubMed:: 26273993
PubMed Central:: PMC4696765
: https://doi.org/10.1021/acs.joc.5b01486

97. Application of a computational neural network to optimize the fluorescence signal from a receptor–ligand interaction on a microfluidic chip

Author:: Maria Ortega; Grady Hanrahan; Marilyn Arceo; Frank A. Gomez
Source:: Electrophoresis 2015 v.36 no.3 pp. 393-397
ISSN:: 0173-0835
Subject:: antibiotics; electrophoresis; experimental design; fluorescence; glass; neural networks
Abstract:: ... We describe the use of a computational neural network platform to optimize the fluorescence upon binding 5‐carboxyfluorescein‐d‐Ala‐d‐Ala‐d‐Ala (5‐FAM(DA)₃) (1) to the antibiotic teicoplanin covalently attached to a glass slide. A three‐level response surface experimental design was used as the first stage of investigation. Subsequently, three defined experimental parameters were examined by the n ...
DOI:: 10.1002/elps.201400288
: https://doi.org/10.1002/elps.201400288

98. Application of a fluorescently labeled trans-acting antigenomic HDV ribozyme to monitor antibiotic–RNA interactions

Author:: Aleksandra Kasprowicz; Aleksandra Kempińska; Barbara Smólska; Jan Wrzesiński; Jerzy Ciesiołka
Source:: Analytical methods 2015 v.7 no.24 pp. 10414-10421
ISSN:: 1759-9679
Subject:: analytical methods; antibiotics; copper; fluorescence; ions; models; mutation; pH; rapid methods; ribozymes; screening
Abstract:: ... In order to determine if a fluorescently labeled trans-acting antigenomic HDV ribozyme can be used to monitor antibiotic–RNA interactions, several parameters that can influence assay sensitivity and reproducibility were tested and optimized. Applicability of the assay for rapid screening of antibiotics targeting the HDV ribozyme was shown by using selected antibiotics and their complexes with copp ...
DOI:: 10.1039/c5ay02953h
: https://doi.org/10.1039/c5ay02953h

99. Application of avian cytokines as immuno-modulating agents

Author:: S. UMAR; M. ARIF; M.A.A. SHAH; M.T. MUNIR; M. YAQOOB; S. AHMED; M.I. KHAN; M. YOUNUS; M. SHAHZAD
Source:: World's poultry science journal 2015 v.71 no.4 pp. 643-654
ISSN:: 1743-4777
Subject:: adverse effects; antibiotics; chickens; cytokines; genes; immune response; immunomodulators; infectious diseases; poultry diseases; profits and margins; vaccination; vaccine adjuvants; vaccines
Abstract:: ... The restricted use of antibiotics in the poultry sector has greatly enhanced the search for environment-friendly alternatives and complementary therapeutic approaches to manage infectious diseases in poultry. Cytokines, as natural immune-modulators, offer alternatives to conventional chemical-based therapeutics. Cytokine usage is becoming more feasible in poultry due to recent advancements in the ...
DOI:: 10.1017/S004393391500238X
: https://doi.org/10.1017/S004393391500238X

100. Application of microalgae biomass in poultry nutrition

Author:: S. ŚWIĄTKIEWICZ; A. ARCZEWSKA-WŁOSEK; D. JÓZEFIAK
Source:: World's poultry science journal 2015 v.71 no.4 pp. 663-672
ISSN:: 1743-4777
Subject:: Chlorella; Spirulina; antibiotics; antioxidants; aquatic plants; biomass; carotenoids; dietary protein; egg quality; egg yolk; eggs; eicosapentaenoic acid; fuel production; growth promotion; immune response; ingredients; long chain polyunsaturated fatty acids; meat; microalgae; nutritive value; omega-3 fatty acids; photosynthesis; pigmentation; poultry; poultry nutrition; protein sources
Abstract:: ... The aim of this review is to discuss the use of microalgae as a feed ingredient in poultry nutrition. Microalgae are unicellular, photosynthetic aquatic plants. They are introduced to poultry diets mainly as a rich source of n-3 long chain polyunsaturated fatty acids, including docohexaenoic and eicosapentaenoic acid, but they can also serve as a protein, microelement, vitamin and antioxidants sou ...
DOI:: 10.1017/S0043933915002457
: https://doi.org/10.1017/S0043933915002457

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1. (Lipo)polysaccharide interactions of antimicrobial peptides

2. 272 cases of rattlesnake envenomation in dogs: Demographics and treatment including safety of F(ab′)2 antivenom use in 236 patients

3. 29-Deoxymaklamicin, a new maklamicin analogue produced by a genetically engineered strain of Micromonospora sp. NBRC 110955

4. A 3’ external transcribed spacer in a tRNA transcript acts as a sponge for small RNAs to prevent transcriptional noise

5. 6-Tosyl-4,5,6,7-Tetrahydrothieno[2,3-c]Pyridine-3-Carboxamide Analogues: Synthesis, Characterization, MO Calculation, and Antibacterial Activity

6. AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?

7. AKTIVITAS ANTIBAKTERI EKSTRAK BUAH ADAS (Foeniculum vulgare, Mill) PADA Vibrio harveyi DAN Vibrio alginolyticus Antibacterial Activity of Fennel (Foeniculum vulgare Mill) Extract on Vibrio alginolyticus and Vibrio harveyi

8. Achieving energy goals at day 4 after admission in critically ill children; predictive for outcome?

9. Acid-activated biochar increased sulfamethazine retention in soils

10. Acorus calamus rhizome extract mediated biosynthesis of silver nanoparticles and their bactericidal activity against human pathogens

11. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity

12. Actinobacterial Flora in Feces of Healthy Cottontail Rabbits (Sylvilagus auduboni)

13. Actinobaculum schaalii bacteremia: A report of two cases

14. Activation of Peroxymonosulfate by Benzoquinone: A Novel Nonradical Oxidation Process

15. Activation of Toxin-Antitoxin System Toxins Suppresses Lethality Caused by the Loss of σᴱ in Escherichia coli

16. Activation of the σᴱ-Dependent Stress Pathway by Conjugative TraR May Anticipate Conjugational Stress

17. The Acute Oral Toxicity of Commonly Used Pesticides in Iran, to Honeybees (Apis Mellifera Meda)

18. Acute toxicological effects on the earthworm Eisenia fetida of 18 common pharmaceuticals in artificial soil

19. Adaptation to NaCl Reduces the Susceptibility of Enterococcus faecalis to Melaleuca alternifolia (Tea Tree) Oil

20. Adherence Reduction of Campylobacter jejuni and Campylobacter coli Strains to HEp-2 Cells by Mannan Oligosaccharides and a High-Molecular-Weight Component of Cranberry Extract

21. Adsorption behavior and mechanisms of ciprofloxacin from aqueous solution by ordered mesoporous carbon and bamboo-based carbon

22. Adsorption behavior of antibiotic in soil environment: a critical review

23. Adsorption of enrofloxacin in presence of Zn(II) on a calcareous soil

24. Adsorptive Removal of Fluoroquinolone Antibiotics Using Bamboo Biochar

25. Advanced physico-chemical characterization of chitosan by means of TGA coupled on-line with FTIR and GCMS: Thermal degradation and water adsorption capacity

26. Advanced trends in controlling Helicobacter pylori infections using functional and therapeutically supplements in baby milk

27. Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota

28. Aggressive, Solid Variant of Alveolar Rhabdomyosarcoma with Cutaneous Involvement in a Juvenile Labrador Retriever

29. Agronomic and environmental effects of land application of residues in short-rotation tree plantations: A literature review

30. Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis

31. Alicyclobacillus in the Fruit Juice Industry: Spoilage, Detection, and Prevention/Control

32. Allopurinol-mediated lignocellulose-derived microbial inhibitor tolerance by Clostridium beijerinckii during acetone–butanol–ethanol (ABE) fermentation

33. Alpha amylase assisted synthesis of TiO2 nanoparticles: Structural characterization and application as antibacterial agents

34. Alterations in the antibacterial potential of Synechococcus spp. PCC7942 under the influence of UV-B radiations on skin pathogens

35. Alternative routes to the acylphloroglucinol rhodomyrtone

36. Amodiaquine–Ciprofloxacin: a potential combination therapy against drug resistant malaria

37. Analysis and evaluation of antibacterial effects of new herbal formulas, AP-001 and AP-002, against Escherichia coli O157:H7

38. Analysis of a draft genome sequence of Kitasatospora cheerisanensis KCTC 2395 producing bafilomycin antibiotics

39. Analysis of swine fecal microbiota at various growth stages

40. Anti-infective vaccination in the 21st century—new horizons for personal and public health

41. Antibacterial Activities of Metabolites from Platanus occidentalis (American sycamore) against Fish Pathogenic Bacteria

42. Antibacterial Activity of Helichrysum italicum Oil on Vegetables and Its Mechanism of Action

43. Antibacterial Coatings: Challenges, Perspectives, and Opportunities

44. Antibacterial Effects of Cinnamon: From Farm to Food, Cosmetic and Pharmaceutical Industries

45. Antibacterial Networks Based on Isosorbide and Linalool by Photoinitiated Process

46. Antibacterial Properties of Nutmeg Oil in Pork and Its Possible Mechanism

47. Antibacterial activities of TiO₂ nanotubes on Porphyromonas gingivalis

48. Antibacterial amphiphiles based on ε-polylysine: synthesis, mechanism of action, and cytotoxicity

49. Antibacterial and osteoinductive capability of orthopedic materials via cation–π interaction mediated positive charge

50. Antibacterial compounds from Salvia adenophora Fernald (Lamiaceae)

51. Antibacterial effect of silver nanoparticles and the modeling of bacterial growth kinetics using a modified Gompertz model

52. Antibacterial evaluation of flavonoid compounds against E. coli by microcalorimetry and chemometrics

53. Antibacterial mechanism of the action of Enteromorpha linza L. essential oil against Escherichia coli and Salmonella Typhimurium

54. Antibacterial mode of action of the hydroethanolic extract of Leonotis nepetifolia (L.) R. Br. involves bacterial membrane perturbations

55. Antibacterial monoclonal antibodies: the next generation?

56. Antibacterial poly(ethylene terephthalate) surfaces obtained from thymyl methacrylate polymerization

57. Antibacterial products of marine organisms

58. Antibacterial properties and cytocompatibility of bio-based nanostructured carbon aerogels derived from silver nanoparticles deposited onto bacterial cellulose

59. Antibacterial properties of extracts of Ludwigia peploides subsp. montevidensis and Ludwigia grandiflora subsp. hexapetala during their cycle of development

60. Antibacterial, antifungal and cytotoxic activities exhibited by endophytic fungi from the Brazilian marine red alga Bostrychia tenella (Ceramiales)

61. Antibiotic Activity of Iron-Sequestering Polymers

62. Antibiotic Efficacy and Characterization of Mangrove Metabolites against UTI Microbes

63. Antibiotic Residue Monitoring Results for Pork, Chicken, and Beef Samples in Vietnam in 2012-2013

64. Antibiotic Resistance Versus Antimicrobial Substances Production by Gram-Negative Foodborne Pathogens Isolated from Minas Frescal Cheese: Heads or Tails?

65. Antibiotic Resistome and Its Association with Bacterial Communities during Sewage Sludge Composting

66. Antibiotic Suppression of Intestinal Microbiota Reduces Heme-Induced Lipoperoxidation Associated with Colon Carcinogenesis in Rats

67. Antibiotic Susceptibility and Functional Group Characterization of Pinna nobilis Metabolites Against Clinical Isolates

68. Antibiotic efficacy is linked to bacterial cellular respiration

69. Antibiotic overuse and Clostridium difficile infections: The Indian paradox and the possible role of dietary practices

70. Antibiotic oxylipins from Alternanthera brasiliana and its endophytic bacteria