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You searched for: Publication Year 2015 Remove constraint Publication Year: 2015 Subject term antioxidants Remove constraint Subject term: antioxidants Subject term ethyl acetate Remove constraint Subject term: ethyl acetate Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Analysis of major antioxidants from extracts of Myrmecodia pendans by UV/visible spectrophotometer, liquid chromatography/tandem mass spectrometry, and high-performance liquid chromatography/UV techniques

Author:
Adam Mekonnen Engida; Sitti Faika; Bich Thuyen Nguyen-Thi; Yi-Hsu Ju
Source:
Yàowù shípǐn fēnxī 2015 v.23 no.2 pp. 303-309
ISSN:
1021-9498
Subject:
antioxidant activity; antioxidants; drugs; ethanol; ethyl acetate; heat; hexane; high performance liquid chromatography; polymers; procyanidins; rosmarinic acid; solvents; spectrophotometers; tandem mass spectrometry
Abstract:
... In the present work, heat reflux extraction with ethanol/water (80:20; v/v) as the solvent was used to extract antioxidants from Myrmecodia pendans. The crude extract (CE) was fractionated using hexane and ethyl acetate. Ethyl acetate fraction (EAF) and aqueous fraction were collected. Antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl-radical radical and ferric reducing power of the CE, E ...
DOI:
10.1016/j.jfda.2014.07.005

2. Anti-inflammatory, antioxidant and anti-acetylcholinesterase activities of Bouvardia ternifolia: potential implications in Alzheimer’s disease

Author:
Giovanni García-Morales; Maira Huerta-Reyes; Manasés González-Cortazar; Alejandro Zamilpa; Enrique Jiménez-Ferrer; Raúl Silva-García; Rubén Román-Ramos; Arturo Aguilar-Rojas
Source:
Archives of pharmacal research 2015 v.38 no.7 pp. 1369-1379
ISSN:
0253-6269
Subject:
Alzheimer disease; Bouvardia; acetylcholinesterase; anti-inflammatory activity; antioxidant activity; antioxidants; chlorogenic acid; ethyl acetate; inflammation; inhibitory concentration 50; neuroprotective effect; neurotoxicity; oleanolic acid; polyphenols; rutin; scopoletin
Abstract:
... Bouvardia ternifolia has been used medicinally to treat inflammation. In the present study, we investigate the anti-Alzheimer’s potential effect of the hydroalcoholic extract of B. ternifolia through evaluation of anti-inflammatory and antioxidant activities, quantification of the percentage inhibition of acetylcholinesterase activity, protection effect against β-amyloid fibrillar-induce neurotoxi ...
DOI:
10.1007/s12272-015-0587-6

3. Antimicrobial and antioxidant phytochemicals in leaf extracts of Bergenia ligulata: a Himalayan herb of medicinal value

Author:
Vasudha Agnihotri; Priyanka Sati; Arvind Jantwal; Anita Pandey
Source:
Natural product research 2015 v.29 no.11 pp. 1074-1077
ISSN:
1478-6427
Subject:
Bergenia; anti-infective properties; antioxidant activity; antioxidants; ethyl acetate; flavonoids; leaf extracts; maceration; medicinal plants; metabolites; methanol; microorganisms; minimum inhibitory concentration; phytopharmaceuticals; solvents
Abstract:
... Phenolic and flavonoid contents in leaf extracts of Bergenia ligulata have been analysed for their contribution in antimicrobial and antioxidant activities. The extracts were prepared in three solvents (separately) following maceration and soxhelt methods. The antimicrobial activity was tested using disc diffusion assay against a range of microorganisms along with the determination of minimum inhi ...
DOI:
10.1080/14786419.2014.980244

4. Antimicrobial, antioxidant and anticancer activities of mangrove associated bacterium Bacillus subtilis subsp. subtilis RG

Author:
R. Ramasubburayan; S. Sumathi; D. Magi Bercy; G. Immanuel; A. Palavesam
Source:
Biocatalysis and agricultural biotechnology 2015 v.4 no.2 pp. 158-165
ISSN:
1878-8181
Subject:
2,2-diphenyl-1-picrylhydrazyl; Gram-negative bacteria; antimicrobial properties; antineoplastic activity; antioxidant activity; antioxidants; breasts; cytotoxicity; ecosystems; ethyl acetate; fungi; growth retardation; humans; inhibitory concentration 50; minimum inhibitory concentration
Abstract:
... In the present investigation an attempt was made to explore the antimicrobial, antioxidant and anticancer activities of ethyl acetate extract of mangrove associated bacterium Bacillus subtilis subsp. subtilis RG. Antimicrobial activity results revealed that, the extract had strongly inhibited growth of gram positive than gram negative bacterial strains and also significantly (P<0.05) inhibited the ...
DOI:
10.1016/j.bcab.2015.01.004

5. Antioxidant and anti-inflammatory effects of Ruta chalepensis L. extracts on LPS-stimulated RAW 264.7 cells

Author:
Mohamed Kacem; Gaëlle Simon; Raphael Leschiera; Laurent Misery; Abdelfattah ElFeki; Nicolas Lebonvallet
Source:
In vitro cellular & developmental biology 2015 v.51 no.2 pp. 128-141
ISSN:
1071-2690
Subject:
Ruta chalepensis; anti-inflammatory activity; antioxidant activity; antioxidants; catalase; ethanol; ethyl acetate; flavonoids; genes; glutathione peroxidase; inducible nitric oxide synthase; inflammation; lipopolysaccharides; macrophages; mice; nitric oxide; nuclear magnetic resonance spectroscopy; oxidative stress; polyphenols; prostaglandin synthase; superoxide dismutase; thiobarbituric acid-reactive substances; transcription factor NF-kappa B
Abstract:
... Ruta chalepensis L. is used in the traditional herbal treatment of various diseases. The aim of this work is to investigate the effect of different extracts of R. chalepensis L. on inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) gene expressions and their antioxidant capacity on murine RAW 264.7 macrophage challenged with lipopolysaccharide (LPS). In fact, this study shows that ...
DOI:
10.1007/s11626-014-9813-7

6. Antioxidant and antiacetylcholinesterase activities of Sorbus torminalis (L.) Crantz (wild service tree) fruits

Author:
Gozde Hasbal; Tugba Yilmaz-Ozden; Ayse Can
Source:
Yàowù shípǐn fēnxī 2015 v.23 no.1 pp. 57-62
ISSN:
1021-9498
Subject:
Sorbus torminalis; acetone; acetylcholinesterase; alpha-tocopherol; antioxidant activity; antioxidants; drugs; ethyl acetate; fruits; methanol; phenolic compounds; quercetin; trees
Abstract:
... In this study, the antioxidant and antiacetylcholinesterase activities of Sorbus torminalis (L.) Crantz fruits were evaluated. Total phenolic and flavonoid compounds, 2,2′-azino-bis (3-ethylbenzothioazoline-6-sulfonic acid), 2,2′-diphenyl-1-picrylhydrazyl, and superoxide anion radicals scavenging activities and ferric-reducing antioxidant power of water, ethyl acetate, acetone, and methanol extrac ...
DOI:
10.1016/j.jfda.2014.06.006

7. Artemisia campestris phenolic compounds have antioxidant and antimicrobial activity

Author:
Wided Megdiche-Ksouri; Najla Trabelsi; Khaoula Mkadmini; Soumaya Bourgou; Amira Noumi; Mejdi Snoussi; Rahma Barbria; Olfa Tebourbi; Riadh Ksouri
Source:
Industrial crops and products 2015 v.63 pp. 104-113
ISSN:
0926-6690
Subject:
Artemisia campestris; Bacillus thuringiensis; Listeria monocytogenes; agar; antibacterial properties; antioxidant activity; antioxidants; antivenoms; chemical composition; coumarins; ethyl acetate; food spoilage; in vitro studies; inhibitory concentration 50; isomers; isorhamnetin; kaempferol; pathogens; phenolic acids; rutin; screening; sesquiterpenoids
Abstract:
... Artemisia campestris subsp. maritima, locally named as “T’gouft” is used as decoction for its anti-inflammatory, antirheumatic, antivenom and antibacterial activities. An efficient and fast technique has been achieved for the screening of the major phenolics in methanolic crude extract (MCE) and two soluble fractions; ethyl acetate (EAF) and water (WF) fractions, from the shoot of A. campestris by ...
DOI:
10.1016/j.indcrop.2014.10.029

8. Bioactives in cactus (Opuntia ficus‐indica) stems possess potent antioxidant and pro‐apoptotic activities through COX‐2 involvement

Author:
Jinhee Kim; Soon Yil Soh; Juha Shin; Chi‐Woung Cho; Young Hee Choi; Sang‐Yong Nam
Source:
Journal of the science of food and agriculture 2015 v.95 no.13 pp. 2601-2606
ISSN:
0022-5142
Subject:
NAD ADP-ribosyltransferase; Opuntia ficus-indica; acetone; antioxidants; apoptosis; breast neoplasms; cacti and succulents; chemoprevention; colon; cytotoxicity; ethyl acetate; hexane; high performance liquid chromatography; humans; methanol; neoplasm cells; polyphenols; prostaglandin synthase; stems
Abstract:
... BACKGROUND: Bioactives extracted from cactus (Opuntia ficus‐indica) stems were investigated for their chemopreventive activities using human cancer cells in vitro. The bioactives present in crude extracts were detected and quantified using high‐performance liquid chromatography. RESULTS: Among all the extracts, such as hexane, ethyl acetate (EtOAc), acetone, methanol (MeOH), and MeOH:water (80:20) ...
DOI:
10.1002/jsfa.6968

9. Chemical composition, antioxidant and antimicrobial activity of Chinese tallow tree leaves

Author:
Rao Fu; Yuting Zhang; Yiran Guo; Fang Chen
Source:
Industrial crops and products 2015 v.76 pp. 374-377
ISSN:
0926-6690
Subject:
Staphylococcus aureus; Triadica sebifera; antibacterial properties; antioxidant activity; antioxidants; chemical composition; ellagic acid; ethanol; ethyl acetate; free radicals; gallic acid; isoquercitrin; leaves; polar compounds; quercetin; rutin
Abstract:
... In the present study, the chemical compositions, antioxidant and antimicrobial activities of fractions of extracts of Chinese tallow tree (CTT, Sapium sebiferum L.) leaves were evaluated. The ethanol extract of CTT leaves was fractionated, then obtained ethyl acetate fraction (EAF), n-butyl alcohol fraction (nBF) and water residue fraction (WF). UPLC-PDA method was adopted for chemical composition ...
DOI:
10.1016/j.indcrop.2015.07.030

10. Different Solvent Fractions of Acanthopanax senticosus Harms Exert Antioxidant and Anti-Inflammatory Activities and Inhibit the Human Kv1.3 Channel

Author:
Jiang Yunyao; Wang Myeong-Hyeon
Source:
Journal of medicinal food 2015 v.18 no.4 pp. 468-475
ISSN:
1557-7600
Subject:
potassium channels; anti-inflammatory activity; messenger RNA; Eleutherococcus senticosus; Xenopus laevis; humans; oocytes; reactive oxygen species; methylene chloride; tumor necrosis factor-alpha; tannins; inducible nitric oxide synthase; prostaglandin synthase; ethyl acetate; quercetin; solvents; anti-inflammatory agents; interleukin-1beta; antioxidant activity
Abstract:
... The potential antioxidant and anti-inflammatory activities of Acanthopanax senticosus Harms were evaluated and its effect on the human Kv1.3 potassium channel was detected. The ethyl acetate fraction possessed the highest phenolic (289.19±7.43 mg tannic acid equivalents/g) and flavonoid (10.80±0.67 mg quercetin equivalents/g) contents and exhibited stronger antioxidant effects than other fractions ...
DOI:
10.1089/jmf.2014.3182

11. Evaluation of polyphenol composition and biological activities of two samples from summer and winter seasons of Ligularia fischeri var. Spiciformis Nakai

Author:
Kaliyaperumal Rekha; Chandran Sivasubramanian; Muthu Thiruvengadam
Source:
Acta biologica Hungarica 2015 v.66 no.2 pp. 179-191
ISSN:
1588-256X
Subject:
2,5-dihydroxybenzoic acid; Ligularia fischeri; anti-infective properties; antioxidant activity; antioxidants; butanol; caffeic acid; ethyl acetate; ferulic acid; gallic acid; kaempferol; leaf extracts; methanol; myricetin; petroleum; polyphenols; protocatechuic acid; pyrogallol; quercetin; salicylic acid; solvents; summer; ultra-performance liquid chromatography; winter
Abstract:
... Phenolic contents, antioxidant and antimicrobial activities were determined by two samples from summer (June) and winter (December) seasons of Ligularia fischeri var. spiciformis Nakai. A total of 24 phenolic compounds were identified by ultra-performance liquid chromatography (UPLC) analysis. Myricetin (1964.35 and 1829.12 μg/g) was the most dominant flavonol compared to quercetin and kaempferol. ...
DOI:
10.1556/018.66.2015.2.5

12. Evaluation of the total antioxidant capacity and antioxidant compounds of different solvent extracts of Chilgoza pine nuts (Pinus gerardiana)

Author:
Lee Yian Hoon; Candy Choo; Mindani I. Watawana; Nilakshi Jayawardena; Viduranga Y. Waisundara
Source:
Journal of functional foods 2015 v.18 pp. 1014-1021
ISSN:
1756-4646
Subject:
2,2-diphenyl-1-picrylhydrazyl; Pinus gerardiana; antioxidants; catechin; cations; epigallocatechin; ethanol; ethyl acetate; hexane; lutein; lycopene; methanol; methylene chloride; nuts; oxygen radical absorbance capacity; solvents; tocopherols
Abstract:
... The total antioxidant capacity of Pinus gerardania, or Chilgoza and the presence of antioxidant compounds which typically exist in pine nuts were quantified. Oxygen radical absorbance capacity assay, ferric reducing antioxidant power, and the 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) and 2, 2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+) radical cation scavenging assays were conducted on ...
DOI:
10.1016/j.jff.2014.07.009

13. Hepatoprotective potential of antioxidant potent fraction from Urtica dioica Linn. (whole plant) in CCl4 challenged rats

Author:
Bhuwan Chandra Joshi; Atish Prakash; Ajudhia N. Kalia
Source:
Toxicology reports 2015 v.2 pp. 1101-1110
ISSN:
2214-7500
Subject:
Urtica dioica; antioxidant activity; antioxidants; blood serum; butanol; chromatography; cinnamic acid; ethyl acetate; ferulic acid; hepatotoxicity; human cell lines; liver; models; petroleum; silica
Abstract:
... The aim of the present study was to isolate hepatoprotective component from Urtica dioica Linn. (whole plant) against CCl₄-induced hepatotoxicity in-vitro (HepG2 cells) and in-vivo (rats) model. Antioxidant activity of hydro alcoholic extract and its fractions petroleum ether fraction (PEF), ethyl acetate fraction (EAF), n-butanol fraction (NBF) and aqueous fraction (AF) were determined by DPPH an ...
DOI:
10.1016/j.toxrep.2015.07.020

14. In vitro anti-oxidant potential of new metabolites from Hypericum oblongifolium (Guttiferae)

Author:
Naila Raziq; Muhammad Saeed; Muhammad Shaiq Ali; Salman Zafar; Muhammad Imran Ali
Source:
Natural product research 2015 v.29 no.24 pp. 2265-2270
ISSN:
1478-6427
Subject:
Clusiaceae; Hypericum; antioxidant activity; antioxidants; ethyl acetate; metabolites; spectroscopy
Abstract:
... Phytochemical investigations on Hypericum oblongifolium led to the isolation of a flavone named folicitin (1) and a bicyclic conjugated lactone, folenolide (2) from the ethyl acetate fraction of methanolic extract. Both metabolites were characterised as new compounds based on detailed spectroscopic analyses. In vitro anti-oxidant potential of both the compounds was evaluated by the DPPH radical sc ...
DOI:
10.1080/14786419.2015.1009064

15. Naphthoquinone and flavonoid constituents from the carnivorous plant Nepenthes mirabilis and their anti-osteoporotic and antioxidant activities

Author:
Nguyen Van Thanh; Nguyen Phuong Thao; Phan Thi Thanh Huong; Sang Hyun Lee; Hae Dong Jang; Nguyen Xuan Cuong; Nguyen Hoai Nam; Phan Van Kiem; Young Ho Kim; Chau Van Minh
Source:
Phytochemistry letters 2015 v.11 pp. 254-259
ISSN:
1874-3900
Subject:
Nepenthes mirabilis; antioxidant activity; antioxidants; bone marrow; branches; carnivorous plants; chloroform; ethyl acetate; flavonoids; in vitro studies; leaves; ligands; macrophages; mice; naphthoquinones; nuclear magnetic resonance spectroscopy; osteoclasts; transcription factor NF-kappa B
Abstract:
... The methanolic extract of Nepenthes mirabilis (Nepenthaceae) showed significant in vitro antioxidant (peroxyl radical-scavenging and reducing effects) and anti-osteoporotic (pre-osteoclastic RAW 264.7 cells) activities. Phytochemical investigation of chloroform and ethyl acetate partitions of N. mirabilis branches and leaves allowed to isolate 13 compounds (1–13), including two new naphthoquinones ...
DOI:
10.1016/j.phytol.2015.01.009

16. Phytochemical Screening and Antioxidant Activity of Syzygium cumini L. Fruit Extracts

Author:
Shila N Gevariya; H P Gajera; Disha D Savaliya; B A Golakiya
Source:
Indian journal of agricultural biochemistry 2015 v.28 no.1 pp. 65-69
ISSN:
0974-4479
Subject:
Syzygium cumini; anthraquinones; antioxidant activity; antioxidants; ethyl acetate; flavanoids; fruit pulp; fruits; glycemic effect; methanol; petroleum; phenol; saponins; seed coat; triterpenoids
Abstract:
... Phytochemical investigation was carried out on four successive extracts (petroleum ether, ethyl acetate, methanol andwater) of Syzygium cumini Linn. (black jamun) fruit parts. The extractive yield increased with increasing polarity of solvents. Preliminary phytochemical screening indicated presence of alkaloids, amino acids, anthraquinones, flavanoids, glycosides, phenol, saponins, steroids, tanni ...

17. Phytochemicals and biological activities of Ruta chalepensis L. growing in Tunisia

Author:
Mohamed Kacem; Imen Kacem; Gaëlle Simon; Amir Ben Mansour; Samia Chaabouni; Abdelfattah Elfeki; Mohamed Bouaziz
Source:
Food bioscience 2015 v.12 pp. 73-83
ISSN:
2212-4292
Subject:
2,2-diphenyl-1-picrylhydrazyl; Ruta chalepensis; alkaloids; antibacterial properties; antioxidant activity; antioxidants; beta-carotene; bleaching; chemical analysis; chemical composition; coumarins; ethanol; ethyl acetate; flavonols; gallic acid; in vitro studies; methanol; phytopharmaceuticals; solvents; Tunisia
Abstract:
... In this paper, the chemical composition of different solvent extracts from Ruta chalepensis L. was determined and their antioxidant and antimicrobial activities were evaluated. Indeed, the total phenol, flavonoids, ortho-diphenols, tannin and flavonols contents of these extracts were quantified, with a total phenolic content varying from 120.57 to 178.00mg Gallic acid equivalents per gram of dry e ...
DOI:
10.1016/j.fbio.2015.08.001

18. Powerful Antioxidant and Pro-Oxidant Properties of Cassia roxburghii DC. Leaves Cultivated in Egypt in Relation to Their Anti-Infectious Activities

Author:
Sahar S. M. El Souda; Nehal Ibrahim; Pierre Perio; Hany Ibrahim; Christel Pigasse-Hénocq; Christine Roques; Françoise Nepveu
Source:
Journal of herbs, spices & medicinal plants 2015 v.21 no.4 pp. 410-425
ISSN:
1540-3580
Subject:
Staphylococcus aureus; parasites; Aspergillus niger; chromatography; spectral analysis; Enterococcus hirae; chloroform; metabolites; petroleum; ethyl acetate; butanol; Pseudomonas aeruginosa; superoxide anion; leaves; Escherichia coli; Candida albicans; Cassia; humans; cytotoxicity; antibacterial properties; Plasmodium falciparum; leaf extracts; methanol; antimalarials; breast neoplasms; fungi; Egypt
Abstract:
... Leaf extracts of Cassia roxburghii DC., prepared in petroleum ether, chloroform, ethyl acetate, butanol, and methanol/water (70:30, v/v), were evaluated as antioxidant, pro-oxidant, anti-infectious, and cytotoxic agents. The major metabolite of each extract was identified by chromatographic and spectroscopic means. The redox properties were assessed with a battery of assays, which revealed that th ...
DOI:
10.1080/10496475.2014.994084

19. Structure activity relationship of bergenin, p-hydroxybenzoyl bergenin, 11-O-galloylbergenin as potent antioxidant and urease inhibitor isolated from Bergenia ligulata

Author:
Anwar Sadat; Ghias Uddin; M. Alam; Ashfaq Ahmad; Bina Shaheen Siddiqui
Source:
Natural product research 2015 v.29 no.24 pp. 2291-2294
ISSN:
1478-6427
Subject:
Bergenia; X-ray diffraction; aerial parts; antioxidant activity; antioxidants; chromatography; dose response; ethanol; ethyl acetate; inhibitory concentration 50; nuclear magnetic resonance spectroscopy; structure-activity relationships; urease; urease inhibitors
Abstract:
... Ethanol extract of the aerial parts of Bergenia ligulata was subjected to solvent–solvent separation followed by various chromatographic techniques that lead to isolation of bergenine (1), p -hydroxybenzoyl bergenin (2), 11- O -galloylbergenin (3) and methyl gallate (4) as major constituents. Ethyl acetate fraction showed a dose-dependent urease inhibitory pattern with IC ₅₀ value of 54μg/mL. Stru ...
DOI:
10.1080/14786419.2015.1004173

20. The discovery of potential anticholinesterase compounds from Achillea millefolium L.

Author:
Handan G. Sevindik; Zühal Güvenalp; Kadir Özden Yerdelen; Hafize Yuca; L. Ömür Demirezer
Source:
Industrial crops and products 2015 v.76 pp. 873-879
ISSN:
0926-6690
Subject:
Achillea millefolium; acetylcholinesterase; active sites; aerial parts; antioxidant activity; antioxidants; butanol; cholinesterase; ethyl acetate; hydrogen bonding; inhibitory concentration 50; luteolin; methanol; neostigmine; rutin
Abstract:
... Luteolin (1), apigenin-7-O-β-D-glucoside (2), luteolin 7-O-β-D-glucoside (3), 6-OH-luteolin 7-O-β-D-glucoside (4) were isolated from Achillea millefolium L. These flavonoids and different polarity fractions of methanol extract from aerial parts of the plant were investigated in terms of antioxidant and anticholinesterase effect. The n-butanol fraction possessed the highest inhibitory activity agai ...
DOI:
10.1016/j.indcrop.2015.05.088