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You searched for: Publication Year 2014 Remove constraint Publication Year: 2014 Subject term Food and Drug Administration Remove constraint Subject term: Food and Drug Administration Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Addressing losses of fresh produce grown in the latin america and the caribbean region due to non-compliance with quality and safety requirements in export markets

Author:
Fonseca, J.M.; Njie, D.N.
Source:
Acta horticulturae 2014 no.1016 pp. 179-185
ISSN:
0567-7572
Subject:
Food and Drug Administration; case studies; cold; developed countries; exports; fruits; markets; pesticide residues; pineapples; postharvest losses; postharvest technology; raw fruit; risk; supply chain; vegetables; Caribbean; Latin America
Abstract:
... An analysis for the non-compliance of fruits and vegetables grown in Latin America and the Caribbean (LAC) with state regulations and quality requirements in international markets was conducted. A review of United States Food and Drug Administration (FDA) data showed that the major reasons for rejection of the LAC fresh fruits and vegetables are dirtiness, pesticide residues and product/labels wit ...

2. Aflatoxins and ochratoxin A in maize of Punjab, Pakistan

Author:
Wajiha Iram; Tehmina Anjum; Mateen Abbas; Abdul Muqeet Khan
Source:
Food additives & contaminants 2014 v.7 no.1 pp. 57-62
ISSN:
1939-3229
Subject:
European Union; Food and Drug Administration; aflatoxin B1; aflatoxin B2; aflatoxin G1; aflatoxin G2; agroecological zones; corn; high performance liquid chromatography; ochratoxin A; seeds; water content; Pakistan
Abstract:
... Aflatoxin and ochratoxin levels were determined in maize samples collected from store houses of 15 districts belonging to three agro-ecological zones of Punjab, Pakistan. Toxins were extracted by Aflaochra immunoaffinity columns and analysed by high-performance liquid chromatography (HPLC). Mean moisture content of maize kernels was recorded above the safe storage level of 15%. Results indicated t ...
DOI:
10.1080/19393210.2013.843205

3. Assessment of the risk of salmonellosis from internally contaminated shell eggs following initial storage at 18 °C (65 °F), compared with 7 °C (45 °F)

Author:
R. Pouillot; K. Hoelzer; G.A. Ramirez; J. deGraft-Hanson; S.B. Dennis
Source:
Food microbiology 2014 v.43 pp. 16-19
ISSN:
0740-0020
Subject:
Food Safety and Inspection Service; Food and Drug Administration; Salmonella Enteritidis; ambient temperature; bacteria; eggs; farms; hatcheries; humans; microbial growth; models; pasteurization; poultry production; risk; risk assessment; salmonellosis; United States
Abstract:
... In the U.S., chicken-breeder farms that supply hatcheries typically store and transport eggs intended for broiler production at a temperature of 18.3 °C (65 °F). However, in case of surplus, some of these eggs may be diverted to human consumption. According to the U.S. Food and Drug Administration's ‘Egg Safety Final Rule,’ shell eggs intended for human consumption are required to be held or trans ...
DOI:
10.1016/j.fm.2014.04.012

4. Barrier properties to surrogates of hydrogenated carbon nano-films deposited on PET by plasma-enhanced chemical vapour deposition

Author:
Éder C. Oliveira; Yolanda Echegoyen; Cristina Nerin; Sandra A. Cruz
Source:
Food additives & contaminants 2014 v.31 no.11 pp. 1914-1927
ISSN:
1944-0057
Subject:
Food and Drug Administration; carbon; detectors; ethylene; gas chromatography; scanning electron microscopy; vapors; United States
Abstract:
... Poly(ethylene terephthalate) resin was contaminated with a series of surrogates using a US Food and Drug Administration protocol. The contaminated samples were coated with two different kinds of hydrogenated amorphous carbon thin films (a-C:H): one with diamond-like hydrogenated amorphous carbon and another with polymer-like hydrogenated carbon (PLCH) phases. To evaluate the barrier properties of ...
DOI:
10.1080/19440049.2014.968637

5. The Beneficial Effect of Total Glucosides of Paeony on Psoriatic Arthritis Links to Circulating Tregs and Th1 Cell Function

Author:
Yi Na Wang; Yu Zhang; Yan Wang; Ding Xian Zhu; Li Qin Xu; Hong Fang; Wei Wu
Source:
Phytotherapy research 2014 v.28 no.3 pp. 372-381
ISSN:
0951-418X
Subject:
Food and Drug Administration; Paeonia; drugs; glucosides; interferon-gamma; natural killer cells; patients; rheumatoid arthritis; tumor necrosis factor-alpha
Abstract:
... Total glycosides of peony (TGP) is a natural immuno‐modulatory drug extracted from traditional Chinese herb peony. It has been approved by State Food and Drug Administration for the treatment of rheumatoid arthritis. However, data of TGP effect on psoriatic arthritis (PsA) is still scarce. In this study, 19 patients with PsA received 12‐week treatment of TGP, and clinical efficacy in joint manifes ...
DOI:
10.1002/ptr.5005
PubMed:
23610010

6. Biogenic amines in commercially produced Yulu, a Chinese fermented fish sauce

Author:
Wei Jiang; Ying Xu; Chunsheng Li; Xiaoyan Dong; Dongfeng Wang
Source:
Food additives & contaminants 2014 v.7 no.1 pp. 25-29
ISSN:
1939-3229
Subject:
Food and Drug Administration; cadaverine; derivatization; fermented fish; fish sauce; fluorescence; high performance liquid chromatography; histamine; putrescine; seafoods; spermidine; spermine; tryptamine; tyramine; China
Abstract:
... Seven biogenic amines were determined in 35 commercially produced Yulu samples from three provinces of China by pre-column derivatisation with dansyl chloride (Dns-Cl) and high-performance liquid chromatography with fluorescence detection (HPLC-FLD). Putrescine, cadaverine, histamine and tyramine were the major biogenic amines (more than 100 mg kg ⁻¹), while tryptamine, spermidine and spermine wer ...
DOI:
10.1080/19393210.2013.831488

7. Cancer glycan biomarkers and their detection – past, present and future

Author:
Sergei A. Svarovsky; Lokesh Joshi
Source:
Analytical methods 2014 v.6 no.12 pp. 3918-3936
ISSN:
1759-9679
Subject:
Food and Drug Administration; analytical methods; biomarkers; diagnostic techniques; disease diagnosis; glycoproteins; inflammation; microarray technology; neoplasms; polysaccharides
Abstract:
... Glycans are important in most biological processes, yet the exact insights into their functions remain enigmatic due to the lack of suitable tools for their analysis. Glycoproteins have recently emerged as valuable biomarkers for a wide range of diseases and some of them (e.g. AFP-L3) have already been approved by the US Food and Drug Administration for cancer diagnosis. Increasing attention is no ...
DOI:
10.1039/c3ay42243g

8. Changes on the horizon for consumer genomics in the EU

Author:
Louiza Kalokairinou; Heidi Carmen Howard; Pascal Borry
Source:
Science 2014 v.346 no.6207 pp. 296-298
ISSN:
0036-8075
Subject:
European Union; Food and Drug Administration; genome; genomics; markets; United States
Abstract:
... Although the direct-to-consumer (DTC) genetic testing market has been developing for over a decade, effective oversight has been challenging, with regulations remaining complex and often unclear. Recent developments indicate that important changes in the regulatory landscape may be imminent. In November 2013, the U.S. Food and Drug Administration (FDA) halted the DTC genetic testing company 23andM ...
DOI:
10.1126/science.1256396

9. Checkpoint blocking antibodies in cancer immunotherapy

Author:
Chrisann Kyi; Michael A. Postow
Source:
FEBS letters 2014 v.588 no.2 pp. 368-376
ISSN:
0014-5793
Subject:
Food and Drug Administration; T-lymphocytes; antibodies; antigens; biomarkers; cytotoxicity; death; drug therapy; immune response; immunomodulators; immunotherapy; ligands; neoplasms; patients; radiotherapy; tissues; United States
Abstract:
... Cancers can be recognized by the immune system, and the immune system may regulate and even eliminate tumors. The development of checkpoint blocking antibodies, such as those directed against cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed death 1 receptor (PD-1), have demonstrated significant recent promise in the treatment of an expanding list of malignancies. While both CTLA-4 and PD-1 ...
DOI:
10.1016/j.febslet.2013.10.015

10. Chronotherapeutic delivery of hydroxypropylmethylcellulose based mini-tablets: An in vitro–in vivo correlation

Author:
Nikhil Biswas; Ranjan Kumar Sahoo; Arijit Guha; Ketousetuo Kuotsu
Source:
International journal of biological macromolecules 2014 v.66 pp. 179-185
ISSN:
0141-8130
Subject:
Food and Drug Administration; absorption; bioavailability; citrates; drugs; guidelines; high performance liquid chromatography; hydrochloric acid; models; prediction; propranolol; rabbits
Abstract:
... The purpose of the study was to develop and internally validate a nonlinear in vitro–in vivo correlation model for a chronotherapeutically programmed HPMC based propranolol HCl (PHCl) mini-tablet. A simple and sensitive HPLC method was developed for the determination of PHCl content in rabbit plasma. The influence of tri-sodium citrate (TSC) on release behaviour was investigated through in vitro d ...
DOI:
10.1016/j.ijbiomac.2014.02.036

11. Cilostazol prevents the degradation of collagen Type II in human chondrocytes

Author:
Weidong Wang; Weibiao Kang; Qiang Tang; Guanfeng Yao; Yuchun Chen; Bizhen Cheng; Kangmei Kong
Source:
Biochemical and biophysical research communications 2014 v.451 pp. 352-355
ISSN:
0006-291X
Subject:
Food and Drug Administration; biomechanics; cartilage; chondrocytes; collagen; disease course; drug therapy; extracellular matrix; humans; inflammation; interferon regulatory factor-1; interleukin-1beta; osteoarthritis; phosphorylation; signal transduction; transactivators; tyrosine
Abstract:
... The alteration of extracellular matrix (ECM) in cartilage during the pathological development of Osteoarthritis (OA) changes the biomechanical environment of chondrocytes, which further drives the progression of the disease in the presence of inflammation. Healthy cartilage matrix mainly contains collagen type II, which is degraded by matrix metalloproteinase13 (MMP13), an important molecules resp ...
DOI:
10.1016/j.bbrc.2014.07.058

12. Colloidal gold nanoparticle conjugates of gefitinib

Author:
Anh Thu Ngoc Lam; Jinha Yoon; Erdene-Ochir Ganbold; Dheeraj K. Singh; Doseok Kim; Kwang-Hwi Cho; So Yeong Lee; Jaebum Choo; Kangtaek Lee; Sang-Woo Joo
Source:
Colloids and Surfaces B: Biointerfaces 2014 v.123 pp. 61-67
ISSN:
0927-7765
Subject:
Food and Drug Administration; Raman spectroscopy; adsorption; antibodies; antineoplastic agents; cell viability; colloids; epidermal growth factor receptors; gold; lung neoplasms; microscopy; nanogold; neoplasm cells; nitrogen; ultraviolet-visible spectroscopy
Abstract:
... Gefitinib (GF) is a US Food and Drug Administration-approved epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor for treating the lung cancers. We fabricated colloidal gold nanoparticle (AuNP) conjugates of the GF anticancer drug by self-assembly to test their potency against A549, NCI-H460, and NCI-H1975 lung cancer cells. GF adsorption on AuNP surfaces was examined by UV–vis absorp ...
DOI:
10.1016/j.colsurfb.2014.08.021

13. A Comparison of the BAX System Method to the US Food and Drug Administration's Bacteriological Analytical Manual and International Organization for Standardization Reference Methods for the Detection of Salmonella in a Variety of Soy Ingredients

Author:
Tamrat Belete; Erin Crowley; Patrick Bird; Joseph Gensic; F. Morgan Wallace
Source:
Journal of food protection 2014 v.77 no.10 pp. 1778-1783
ISSN:
0362-028X
Subject:
Food and Drug Administration; Salmonella Mbandaka; Salmonella Tennessee; ingredients; international organizations; peptones; polymerase chain reaction; regrowth; soy protein
Abstract:
... The performances of two DuPont BAX System PCR assays for detecting Salmonella on a variety of low-moisture soy ingredients were evaluated against the U.S. Food and Drug Administration's Bacteriological Analytical Manual (FDA BAM) method or the International Organization for Standardization (ISO) 6579 reference method. These evaluations were conducted as a single laboratory validation at an ISO 170 ...
DOI:
10.4315/0362-028X.JFP-14-063

14. Content and Composition of Fatty Acids in Marine Oil Omega-3 Supplements

Author:
Cynthia Tyburczy Srigley; Jeanne I. Rader
Source:
Journal of agricultural and food chemistry 2014 v.62 no.29 pp. 7268-7278
ISSN:
0021-8561
Subject:
Food and Drug Administration; cis-trans isomers; dietary supplements; docosahexaenoic acid; eicosapentaenoic acid; fatty acid composition; flame ionization; health claims; ionic liquids; oils; omega-3 fatty acids; trans fatty acids; United States
Abstract:
... Marine oil omega-3 supplements are among the most frequently consumed dietary supplements in the United States. However, few studies have evaluated the overall fatty acid composition of these products. We investigated the content and composition of fatty acids in 46 commercially available marine oil omega-3 supplements by gas chromatography with flame ionization detection using the 200 m SLB-IL111 ...
DOI:
10.1021/jf5016973

15. Correlation of antituberculosis drug-related liver injury and liver function monitoring: A 12-year experience of the Taiwan Drug Relief Foundation

Author:
Lan-Hui Chih; Angela W.F. On; Yi-Shin Huang
Source:
Yàowù shípǐn fēnxī 2014 v.22 no.3 pp. 356-362
ISSN:
1021-9498
Subject:
liver function; bilirubin; liver; blood serum; monitoring; Food and Drug Administration; alanine transaminase; drugs; drug toxicity; odds ratio; confidence interval; hepatitis B; mortality; patients; databases; disease course; hepatotoxicity; Taiwan
Abstract:
... Antituberculosis drug-related liver injury (ATLI) is the most prevalent hepatotoxicity in many countries. Whether monitoring liver tests is beneficial to prevent this potentially grave adverse drug reaction (ADR) is open to debate. The Taiwan Drug Relief Foundation (TDRF) was established by the Taiwan Food and Drug Administration to collect severe cases of ADR and carry out drug injury relief task ...
DOI:
10.1016/j.jfda.2013.10.001

16. Current studies on sucrose isomerase and biological isomaltulose production using sucrose isomerase

Author:
Wanmeng Mu; Wenjing Li; Xiao Wang; Tao Zhang; Bo Jiang
Source:
Applied microbiology and biotechnology 2014 v.98 no.15 pp. 6569-6582
ISSN:
0175-7598
Subject:
Food and Drug Administration; catalytic activity; digestion; energy; fermentation; glycemic index; insulin; isomaltulose; isomerases; isomers; sucrose; Japan; United States
Abstract:
... Isomaltulose is a natural isomer of sucrose. It is widely used as a functional sweetener with promising properties, including slower digestion, lower glycemic index, prolonged energy release, lower insulin reaction, and less cariogenicity. It has been approved as a safe sucrose substitute by the Food and Drug Administration of the US; Ministry of Health, Labor and Welfare of Japan; and the Commiss ...
DOI:
10.1007/s00253-014-5816-2
PubMed:
24866943

17. Delivery of Selective Agents via Time-Delayed Release Tablets Improves Recovery of Listeria monocytogenes Injured by Acid and Nitrite

Author:
Nyarko, Esmond; D'Amico, Dennis; Mach, Patrick; Xia, Wensheng; Donnelly, Catherine
Source:
Journal of food protection 2014 v.77 no.5 pp. 772-780
ISSN:
0362-028X
Subject:
Food and Drug Administration; Listeria monocytogenes; analysis of variance; culture media; international organizations; meat; milk; nitrites; Vermont
Abstract:
... Listeria selective enrichment media are designed to enhance the isolation of the organism and increase the chances of detection. Drawbacks include the requirements for prolonged sample incubation (48 to 72 h) and manual addition of selective agents, which may be a source of contamination. Modified Listeria recovery broth (mLRB) is a proprietary enrichment medium formulated to facilitate the recove ...
DOI:
10.4315/0362-028X.JFP-13-315

18. Detection of isolation of Salmonella spp. in animal feeds from 2007-2011

Author:
Yi-Cheng Hsieh; Kyung-Min Lee; Toni Poole; Mick Runyon; Ben Jones; Timothy J. Herrman
Source:
International journal of regulatory science 2014 v.2 no.1 pp. 14-27
ISSN:
2372-4048
Subject:
screening; risk; bacterial contamination; feeds; monitoring; Food and Drug Administration; serotypes; Salmonella Typhimurium; polymerase chain reaction; feed contamination; rodents; food safety; pathogens; Texas
Abstract:
... Salmonella species (spp.) are zoonotic pathogens that contaminate animal ingredients and finished feed and represent a significant human food safety hazard as identified by the Codex Animal Feed Taskforce. The United States (US) Food and Drug Administration (FDA) has promulgated regulations prohibiting Salmonella contamination in feed and has published a guidance document expressing their current ...
Handle:
10113/60556

19. Development and Validation of a Sensitive UPLC-ESI-MS/MS Method for the Simultaneous Quantification of 15 Endocannabinoids and Related Compounds in Milk and Other Biofluids

Author:
Gouveia-Figueira Sandra; Nording Malin L.
Source:
Analytical chemistry 2014 v.86 no.2 pp. 1186-1195
ISSN:
1520-6882
Subject:
Food and Drug Administration; amides; cattle; detection limit; electrospray ionization mass spectrometry; elks; fatty acids; glycerol; guidelines; infants; liquid chromatography; milk; United States
Abstract:
... The endocannabinoid (eCB) system has gained an increasing interest over the past decades since the discovery of anandamide and 2-arachidonoyl glycerol (2-AG). These, and structurally related compounds, are associated with a wide variety of physiological processes. For instance, eCB levels in milk have been associated with infants’ feeding and sleeping behavior. A method based on ultraperformance l ...
DOI:
10.1021/ac403352e

20. Development and validation of a micellar liquid chromatography-based method to quantify melamine in swine kidney

Author:
Beatriz Beltrán-Martinavarro; Juan Peris-Vicente; Samuel Carda-Broch; Josep Esteve-Romero
Source:
Food control 2014 v.46 pp. 168-173
ISSN:
0956-7135
Subject:
1-propanol; Food and Drug Administration; absorbance; feeds; food chain; food quality; guidelines; high performance liquid chromatography; humans; kidneys; melamine; methanol; pH; poisoning; poultry feeding; protein content; screening; sodium dodecyl sulfate; supermarkets; swine; toxic substances
Abstract:
... Melamine is a toxic compound illegally added to animal feed to falsely boost protein content. This represents a strong threat to consumer's health, as melamine can reach human through the food chain. An easy and reliable micellar liquid chromatography-method was developed to detect melamine in swine kidney. The analyte was extracted by shaking in methanol. Melamine was eluted from the HPLC column ...
DOI:
10.1016/j.foodcont.2014.05.027

21. Development and validation of an ELISA kit for the detection of ricin toxins from biological specimens and environmental samples

Author:
Hsiao Ying Chen; Hung Tran; Ling Yann Foo; Tracey Wenhui Sew; Weng Keong Loke
Source:
Analytical and bioanalytical chemistry 2014 v.406 no.21 pp. 5157-5169
ISSN:
1618-2642
Subject:
Food and Drug Administration; Ricinus communis; antitoxins; blood; diagnostic sensitivity; disease control; enzyme-linked immunosorbent assay; fearfulness; feces; markets; oral exposure; patients; poisoning; public health; ricin; seed extracts; seeds; therapeutics; toxins; vaccines
Abstract:
... Ricin is a toxin that can be easily extracted from seeds of Ricinus communis plants. Ricin is considered to be a major bio-threat as it can be freely and easily acquired in large quantities. A deliberate release of such toxin in civilian populations would very likely overwhelm existing public health systems, resulting in public fear and social unrest. There is currently no commercially available o ...
DOI:
10.1007/s00216-014-7934-1

22. Dimethyl fumarate protection against collagen II degradation

Author:
Ye Li; Jie Tang; Yong Hu
Source:
Biochemical and biophysical research communications 2014 v.454 pp. 257-261
ISSN:
0006-291X
Subject:
Food and Drug Administration; collagen; dimethyl fumarate; drug therapy; osteoarthritis; sclerosis; tumor necrosis factor-alpha
Abstract:
... Degradation of collagen type II caused by pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) is one of the major pathological characteristics of osteoarthritis (OA). Dimethyl fumarate (DMF) is a medication approved by the US Food and Drug Administration (FDA) as an oral multiple sclerosis (MS) therapy. In this study, we found that DMF ameliorated collagen type II degradation by ...
DOI:
10.1016/j.bbrc.2014.10.005

23. Discrimination of Cocoa Beans According to Geographical Origin by Electronic Tongue and Multivariate Algorithms

Author:
Ernest Teye; Xingyi Huang; Fangkai Han; Francis Botchway
Source:
Food analytical methods 2014 v.7 no.2 pp. 360-365
ISSN:
1936-9751
Subject:
Food and Drug Administration; algorithms; cocoa beans; discriminant analysis; electronic tongue; models; prediction; principal component analysis; quality control; Ghana
Abstract:
... Electronic tongue as an advanced and novel emerging technology has been successfully utilized for the rapid identification of cocoa beans according to their geographical locations. Seven categories of cocoa beans from Ghana were used in this experiment. Electronic tongue system was used for data acquisition while three pattern recognition methods were applied comparatively to build discrimination ...
DOI:
10.1007/s12161-013-9634-4

24. Dual hairpin-like molecular beacon based on coralyne-adenosine interaction for sensing melamine in dairy products

Author:
Guangfeng Wang; Yanhong Zhu; Ling Chen; Xiaojun Zhang
Source:
Talanta 2014 v.129 pp. 398-403
ISSN:
0039-9140
Subject:
Food and Drug Administration; adenosine; dissociation; fluorescence; fluorescent dyes; melamine; milk; protocols; safety standards; thymine
Abstract:
... This study presents a novel dual hairpin-like molecular beacon (MB) for the selective and sensitive detection of melamine (MA) based on the conjugation of MA and thymine. In this protocol, the coordination between coralyne and adenosine (A) leaded a dual hairpin-like MB and the fluorophore–quencher pair is close proximity resulting in the fluorescence quenching. With the addition of MA, it conjuga ...
DOI:
10.1016/j.talanta.2014.05.046

25. Edible films from pectin: Physical-mechanical and antimicrobial properties - A review

Author:
Paula Judith Pérez Espitia; Wen-Xian Du; Roberto de Jesús Avena-Bustillos; Nilda de Fátima Ferreira Soares; Tara H. McHugh
Source:
Food hydrocolloids 2014 v.35 pp. 287-296
ISSN:
0268-005X
Subject:
laws and regulations; food packaging; milk; microbial growth; beverages; Food and Drug Administration; cell walls; acids; biodegradability; edible films; biocompatibility; antimicrobial properties; pectins; ice cream; yogurt; jams; methanol; GRAS substances; food industry; microorganisms; esterification; polymers; active ingredients; permeability; gelation
Abstract:
... Pectin is one of the main components of the plant cell wall chemically constituted by poly α1–4-galacturonic acids. According to its degree of esterification with methanol, pectin can be classified as high methoxyl pectin or low methoxyl pectin. In food industry, pectin is listed as generally recognized as safe (GRAS) by the Food and Drug Administration and is used as gelling, stabilizing, or thic ...
DOI:
10.1016/j.foodhyd.2013.06.005

26. Effects of halogenated aromatics/aliphatics and nitrogen(N)-heterocyclic aromatics on estimating the persistence of future pharmaceutical compounds using a modified QSAR model

Author:
Seung Joo Lim; Peter Fox
Source:
Science of the total environment 2014 v.470-471 pp. 348-355
ISSN:
0048-9697
Subject:
Food and Drug Administration; aerobic conditions; aromatic compounds; biodegradability; drugs; equations; half life; models; nitrogen; oxidation; quantitative structure-activity relationships; sorption; United States
Abstract:
... The effects of halogenated aromatics/aliphatics and nitrogen(N)-heterocyclic aromatics on estimating the persistence of future pharmaceutical compounds were investigated using a modified half life equation. The potential future pharmaceutical compounds investigated were approximately 2000 pharmaceutical drugs currently undergoing the United States Food and Drug Administration (US FDA) testing. EPI ...
DOI:
10.1016/j.scitotenv.2013.09.089

27. Elements of concern in fillets of bighead and silver carp from the Illinois River, Illinois

Author:
Jeffrey M. Levengood; David J. Soucek; Gregory G. Sass; Amy Dickinson; John M. Epifanio
Source:
Chemosphere 2014 v.104 pp. 63-68
ISSN:
0045-6535
Subject:
Food and Drug Administration; Hypophthalmichthys molitrix; Hypophthalmichthys nobilis; arsenic; carp; correlation; detection limit; fish fillets; food contamination; humans; mercury; methylmercury compounds; protein sources; risk assessment; rivers; selenium; Illinois; Illinois River; Mississippi River
Abstract:
... Efforts to control invasive bighead (Hypophthalmichthys nobilis) and silver carp (H. molitrix) may include harvest for human consumption. We measured concentrations of arsenic (As), mercury (Hg), and selenium (Se) in fillets from silver and bighead carp collected from the lower Illinois River, Illinois, USA, to determine whether concentrations were of health concern and differed by species, size, ...
DOI:
10.1016/j.chemosphere.2013.10.058

28. Enhanced penetration of moxifloxacin into rat prostate tissue evidenced by microdialysis

Author:
Felipe K. Hurtado; João Victor Laureano; Graziela de A. Lock; Hartmut Derendorf; Teresa Dalla Costa
Source:
International journal of antimicrobial agents 2014 v.44 no.4 pp. 327-333
ISSN:
0924-8579
Subject:
Food and Drug Administration; active transport; biopsy; blood sampling; catheters; ciprofloxacin; computer software; intracellular space; intravenous injection; levofloxacin; microdialysis; models; moxifloxacin; norfloxacin; pharmacokinetics; prostate gland; prostatitis; rats; tissue distribution; United States
Abstract:
... Moxifloxacin is reported to have increased distribution into the prostate compared with older fluoroquinolones such as norfloxacin and ciprofloxacin, being able to reach tissue-to-plasma concentration ratios greater than unity. However, most of these studies use tissue homogenates derived from biopsy samples, which can lead to overestimation of free concentrations as fluoroquinolones tend to accum ...
DOI:
10.1016/j.ijantimicag.2014.06.011

29. An Exploratory Evaluation of the Utility of Transcriptional and Urinary Kidney Injury Biomarkers for the Prediction of Aristolochic Acid–Induced Renal Injury in Male Rats

Author:
T. C. Fuchs; A. Mally; A. Wool; M. Beiman; P. Hewitt
Source:
Veterinary pathology v.51 no.3 pp. 680-694
ISSN:
1544-2217
Subject:
Food and Drug Administration; animal pathology; aristolochic acids; biomarkers; blood serum; calbindin; creatinine; drugs; epithelium; gene expression; glutathione transferase; histopathology; kidneys; laboratory animals; males; medical equipment; models; nephrotoxicity; neutrophils; osteopontin; prediction; quantitative polymerase chain reaction; rats; toxicology; transcription (genetics); urea nitrogen; urine; vascular endothelial growth factors
Abstract:
... The predictive value of different urinary and transcriptional biomarkers was evaluated in a proof-of-principle toxicology study in rats using aristolochic acid (AA), a known nephrotoxic agent. Male Wistar rats were orally dosed with 0.1, 1, or 10 mg/kg for 12 days. Urine was collected on days 1, 5, and 12 over 24 hours. Gene expression analysis was also conducted using quantitative real-time polym ...
DOI:
10.1177/0300985813498779

30. FDA Ruling and Nutritionally Focused Menus: Alternative Strategies to Comply with the U.S. Federal Guidelines

Author:
Meschelle Davis; Milos Bujisic; H. G. Parsa; Dipendra Singh
Source:
Journal of foodservice business research 2014 v.17 no.4 pp. 283-300
ISSN:
1537-8039
Subject:
Americans; Food and Drug Administration; business enterprises; color; consumer preferences; dietary recommendations; guidelines; menu planning; nutrition labeling; overweight; public health; reading; restaurants; United States
Abstract:
... Research indicates that 65% of Americans over the age of 20 years old are considered overweight. To address this public health issue, the U.S. Food and Drug Administration has proposed new nutritional guidelines for restaurant menus. This study includes development and redesigning of drive-thru menus to comply with the FDA guidelines. An experiment was conducted using real drive-thru menus from se ...
DOI:
10.1080/15378020.2014.945888

31. A Fast and Validated Method for the Determination of Malondialdehyde in Fish Liver Using High‐Performance Liquid Chromatography with a Photodiode Array Detector

Author:
Mohammad Faizan; Tuba Esatbeyoglu; Banu Bayram; Gerald Rimbach
Source:
Journal of food science 2014 v.79 no.4 pp. C484
ISSN:
0022-1147
Subject:
Food and Drug Administration; acetic acid; derivatization; detection limit; fish; high performance liquid chromatography; lipid peroxidation; liver; malondialdehyde; United States
Abstract:
... Malondialdehyde (MDA) is a biomarker of lipid peroxidation and is present in foods and biological samples such as plasma. A high‐performance liquid chromatography (HPLC) method was applied to determine MDA in fish liver samples after derivatization with 2,4‐dinitrophenylhydrazine (DNPH) using a ODS2 column (10 cm × 4.6 mm, 3 μm) and a photodiode array detector. The mobile phase consisted of 0.2% a ...
DOI:
10.1111/1750-3841.12412
PubMed:
24621264

32. H7N9 and Other Pathogenic Avian Influenza Viruses Elicit a Three-Pronged Transcriptomic Signature That Is Reminiscent of 1918 Influenza Virus and Is Associated with Lethal Outcome in Mice

Author:
Juliet Morrison; Laurence Josset; Nicolas Tchitchek; Jean Chang; Jessica A. Belser; David E. Swayne; Mary J. Pantin-Jackwood; Terrence M. Tumpey; Michael G. Katze
Source:
Journal of virology 2014 v.88 no.18 pp. 10556-10568
ISSN:
0022-538X
Subject:
Food and Drug Administration; Influenza A virus; animal disease models; avian influenza; cytokines; drugs; genes; host-pathogen relationships; lipid metabolism; mice; pandemic; pathogenesis; pathogenicity; transcription (genetics); transcriptome; transcriptomics; virulent strains; viruses
Abstract:
... Modulating the host response is a promising approach to treating influenza, caused by a virus whose pathogenesis is determined in part by the reaction it elicits within the host. Though the pathogenicity of emerging H7N9 influenza virus in several animal models has been reported, these studies have not included a detailed characterization of the host response following infection. Therefore, we cha ...
Handle:
10113/59864
DOI:
10.1128/JVI.00570-14
PubMed:
24991006
PubMed Central:
PMC4178843

33. Human exposure to trace metals and possible public health risks via consumption of mussels Mytilus galloprovincialis from the Adriatic coastal area

Author:
Mihajlo Jović; Slavka Stanković
Source:
Food and chemical toxicology 2014 v.70 pp. 241-251
ISSN:
0278-6915
Subject:
European Union; Food and Drug Administration; Mytilus galloprovincialis; United States Environmental Protection Agency; cadmium; coasts; cobalt; copper; humans; iron; lead; manganese; mercury; mussels; nickel; public health; risk; toxicology; zinc; Montenegro; United States
Abstract:
... Considering the growing concern due to different levels of anthropogenic loadings, the main purpose of this study was to identify the levels of trace metals (Fe, Mn, Cu, Zn, Co, Ni, Cd, Pb and Hg) in the mussels Mytilus galloprovincialis sampled along the marine coast of Boka Kotorska Bay, Montenegro. In comparison with the permissible limits set by the EU and the US FDA, all trace metal concentra ...
DOI:
10.1016/j.fct.2014.05.012

34. In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS

Author:
Aitor Carretero; Zacarías León; Juan Carlos García-Cañaveras; Ángela Zaragoza; María José Gómez-Lechón; María Teresa Donato; Agustín Lahoz
Source:
Analytical and bioanalytical chemistry 2014 v.406 no.22 pp. 5465-5476
ISSN:
1618-2642
Subject:
DNA damage; Food and Drug Administration; biomarkers; blood serum; clinical trials; correlation; derivatization; fatty liver; fractionation; guidelines; hepatocytes; homeostasis; in vitro studies; in vivo studies; lipids; liver; models; oxidation; oxidative stress; patients; proteins; rats; screening; signal transduction; tandem mass spectrometry; toxicity; ultra-performance liquid chromatography
Abstract:
... Multiple analytical methods are required to comprehensively assess oxidative homeostasis and specific damage to macromolecules. Our aim was to develop a straightforward strategy for the fast assessment of global oxidative status and specific damage to DNA, proteins, and lipids. To this end, an analytical method, based on ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS ...
DOI:
10.1007/s00216-014-7983-5

35. In vivo imaging of intestinal helminths by capsule endoscopy

Author:
Koichi Soga; Osamu Handa; Minoru Yamada; Junichi Sakagami; Nobuaki Yagi; Yuji Naito; Toshikazu Yoshikawa; Yoshito Itoh; Naoki Arizono
Source:
Parasitology international 2014 v.63 no.1 pp. 221-228
ISSN:
1383-5769
Subject:
Crohn disease; Food and Drug Administration; anus; capsule endoscopy; colonoscopy; endoscopic retrograde cholangiopancreatography; helminthiasis; helminths; hemorrhage; image analysis; morbidity; mortality; mouth; small intestine; stomach
Abstract:
... This review examines the use of digestive endoscopy to visualize intestinal helminths. The infections caused by these parasites are responsible for high levels of morbidity and mortality. These helminths can be visualized using gastroduodenal endoscopy, endoscopic retrograde cholangiopancreatography, and colonoscopy. Endoscopic examination of the small bowel is limited by its considerable length a ...
DOI:
10.1016/j.parint.2013.09.006

36. The Institute of Medicine, the Food and Drug Administration, and the calcium conundrum

Author:
Shristi Neupane; Stephen J Knohl
Source:
Public health nutrition 2014 v.17 no.8 pp. 1865-1867
ISSN:
1475-2727
Subject:
Food and Drug Administration; National Health and Nutrition Examination Survey; adults; antacids; calcium; diet; females; homeostasis; males; medicine; patients; risk; United States
Abstract:
... In the present article we aim to bring forward the apparent disconnect between two US government-sponsored entities – the Institute of Medicine (IOM) and the Food and Drug Administration (FDA) – regarding the safe upper limit of Ca intake. In light of the 2011 US Congress-appointed IOM report indicating an upper limit of elemental Ca intake of 2000–2500 mg/d in adults (based on age group), it is p ...
DOI:
10.1017/S1368980014000184
PubMed:
24621615

37. Integration of clinical point-of-care requirements in a DNA microarray genotyping test

Author:
Bieke Van Dorst; Amelieke Cremers; Karolien Jans; Trees Van Domburg; Kim Steegen; Chengjun Huang; Christian Dorrer; Liesbet Lagae; Gerben Ferwerda; Lieven J. Stuyver
Source:
Biosensors & bioelectronics 2014 v.61 pp. 605-611
ISSN:
0956-5663
Subject:
DNA; DNA microarrays; Food and Drug Administration; Streptococcus pneumoniae; antibiotic resistance; biosensors; blood; blood sampling; genotyping; humans; pathogens
Abstract:
... Various proof-of-concept studies have shown the potential of biosensors with a high multiplex detection capability for the readout of DNA microarrays in a lab-on-a-chip. This is particularly interesting for the development of point-of-care genotyping tests, to screen for multiple pathogens and/or antibiotic resistance patterns. In this paper, an assay workflow is presented, suited for the developm ...
DOI:
10.1016/j.bios.2014.05.071

38. Introduction of solid-phase microextraction as a high-throughput sample preparation tool in laboratory analysis of prohibited substances

Author:
Ezel Boyacı; Krzysztof Gorynski; Angel Rodriguez-Lafuente; Barbara Bojko; Janusz Pawliszyn
Source:
Analytica chimica acta 2014 v.809 pp. 69-81
ISSN:
0003-2670
Subject:
Food and Drug Administration; analytical chemistry; desorption; ionic strength; liquid chromatography; mass spectrometry; models; pH; quantitative analysis; retrospective studies; solid phase microextraction; spectrometers; urinalysis; washing
Abstract:
... A fully automated, high-throughput method based on thin-film solid-phase microextraction (SPME) and liquid chromatography-mass spectrometry was developed for simultaneous quantitative analysis of 110 doping compounds, selected from ten classes and varying in physical and chemical properties. Among four tested extraction phases, C18 blades were chosen, as they provided optimum recoveries and the lo ...
DOI:
10.1016/j.aca.2013.11.056

39. Introduction: Reducing Salmonella Enteritidis contamination of shell eggs

Author:
P.H. Patterson; K. Venkitanarayanan; S. Kariyawasam
Source:
Journal of applied poultry research 2014 v.23 no.2 pp. 323-329
ISSN:
1056-6171
Subject:
Food and Drug Administration; Salmonella Enteritidis; egg quality; eggs; food pathogens; food safety; on-farm research; public health; quality control
Abstract:
... Salmonella Enteritidis is a leading food-borne pathogen in the United States, with many outbreaks in humans traced back to shell eggs. As a result, the implementation of effective strategies for reducing Salmonella Enteritidis in commercial layer flocks has become a critical public health and economic objective. In this paper, we share the findings of 2 multistate USDA-National Integrated Food Saf ...
DOI:
10.3382/japr.2014-00940

40. Label-free turn-on fluorescent detection of melamine based on the anti-quenching ability of Hg2+ to gold nanoclusters

Author:
Haichao Dai; Yan Shi; Yilin Wang; Yujing Sun; Jingting Hu; Pengjuan Ni; Zhuang Li
Source:
Biosensors & bioelectronics 2014 v.53 pp. 76-81
ISSN:
0956-5663
Subject:
Food and Drug Administration; biosensors; cost effectiveness; detection limit; dried milk; fluorescence; gold; melamine; mercury; nanoparticles; raw milk
Abstract:
... In this work, we proposed a facile, environmentally friendly and cost-effective assay for melamine with BSA-stabilized gold nanoclusters (AuNCs) as a fluorescence reader. Melamine, which has a multi-nitrogen heterocyclic ring, is prone to coordinate with Hg2+. This property causes the anti-quenching ability of Hg2+ to AuNCs through decreasing the metallophilic interaction between Hg2+ and Au+. By ...
DOI:
10.1016/j.bios.2013.09.034

41. Laboratory and Pilot-Scale Dead-End Ultrafiltration Concentration of Sanitizer-Free and Chlorinated Lettuce Wash Water for Improved Detection of Escherichia coli O157:H7

Author:
Sonia Magana; Sarah M. Schlemmer; Gordon R. Davidson; Elliot T. Ryser; Daniel V. Lim
Source:
Journal of food protection 2014 v.77 no.8 pp. 1260-1268
ISSN:
0362-028X
Subject:
Escherichia coli O157; Food and Drug Administration; chlorine; electrochemiluminescence; filters; green fluorescent protein; immunoassays; lettuce; monitoring; pathogens; plate count; rapid methods; selective media; sieving; ultrafiltration; Michigan
Abstract:
... An automated dead-end (single pass, no recirculation) ultrafiltration device, the Portable Multi-use Automated Concentration System (PMACS), was evaluated as a means to concentrate Escherichia coli O157:H7 from 40 liters of simulated commercial lettuce wash water. The assessment included generating, sieving, and concentrating sanitizer-free lettuce wash water, either uninoculated or inoculated wit ...
DOI:
10.4315/0362-028X.JFP-13-421

42. Lead in rice: Analysis of baseline lead levels in market and field collected rice grains

Author:
Gareth J. Norton; Paul N. Williams; Eureka E. Adomako; Adam H. Price; Yongguan Zhu; Fang-Jie Zhao; Steve McGrath; Claire M. Deacon; Antia Villada; Alessia Sommella; Ying Lu; Lei Ming; P. Mangala C.S. De Silva; Hugh Brammer; Tapash Dasgupta; M. Rafiqul Islam; Andrew A. Meharg
Source:
Science of the total environment 2014 v.485-486 pp. 428-434
ISSN:
0048-9697
Subject:
European Union; Food and Drug Administration; children; field experimentation; genotype; genotype-environment interaction; lead; markets; pregnant women; rice; risk; risk assessment; surveys
Abstract:
... In a large scale survey of rice grains from markets (13 countries) and fields (6 countries), a total of 1578 rice grain samples were analysed for lead. From the market collected samples, only 0.6% of the samples exceeded the Chinese and EU limit of 0.2μgg−1 lead in rice (when excluding samples collected from known contaminated/mine impacted regions). When evaluating the rice grain samples against ...
DOI:
10.1016/j.scitotenv.2014.03.090

43. Males exceed females in PCB concentrations of cisco (Coregonus artedi) from Lake Superior

Author:
Charles P. Madenjian; Daniel L. Yule; Sergei M. Chernyak; Linda J. Begnoche; Eric K. Berglund; Edmund J. Isaac
Source:
Science of the total environment 2014 v.493 pp. 377-383
ISSN:
0048-9697
Subject:
Coregonus; Food and Drug Administration; eggs; energy metabolism; females; fisheries; guidelines; males; models; polychlorinated biphenyls; resting metabolic rate; somatic cells; spawning; Lake Superior
Abstract:
... We determined whole-fish polychlorinated biphenyl (PCB) concentrations of 25 male and 25 female age-7 ciscoes (Coregonus artedi) captured from a spawning aggregation in Thunder Bay, Lake Superior, during November 2010. We also determined PCB concentrations in the ovaries and somatic tissue of five additional female ciscoes (ages 5–22). All 55 of these ciscoes were in ripe or nearly ripe condition. ...
DOI:
10.1016/j.scitotenv.2014.06.007

44. Matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry as a confirmation procedure in internationally recognised standard test methods for Cronobacter sakazakii

Author:
Denise Lindsay; Bruce Hill; Pierre Venter
Source:
International dairy journal 2014 v.39 no.2 pp. 276-283
ISSN:
0958-6946
Subject:
Cronobacter sakazakii; Food and Drug Administration; agar; culture media; dairy products; desorption; ionization; laboratory experimentation; matrix-assisted laser desorption-ionization mass spectrometry; phenotype; rapid methods; United States
Abstract:
... Matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) is accepted as a reliable, rapid technique for confirming microorganism identity. In this study, MALDI-TOF MS was evaluated for replacement of the current biochemical phenotype confirmation steps in the International Standardisation Organisation (ISO) and US Food and Drug Administration (USFDA) methods for ...
DOI:
10.1016/j.idairyj.2014.07.011

45. Mercury Content in Commercially Available Finfish in the United States

Author:
Dennis P. Cladis; Alison C. Kleiner; Charles R. Santerre
Source:
Journal of food protection 2014 v.77 no.8 pp. 1361-1366
ISSN:
0362-028X
Subject:
Food and Drug Administration; Gadus morhua; Ictalurus punctatus; Xiphias gladius; cod (fish); mackerel; markets; mercury; muscle tissues; pollock; salmon; seafoods; Great Lakes; New England region; United States
Abstract:
... Seventy-seven finfish species (300 composites of three fish) were obtained from commercial vendors in six regions of the United States: Great Lakes, mid-Atlantic, New England, northwest, southeast, and southwest. Total mercury in fish muscle tissue ranged from 1 ppb (channel catfish) to 1,425 ppb (king mackerel). Of the top 10 most commonly consumed seafoods in the United States, all finfish speci ...
DOI:
10.4315/0362-028X.JFP-14-097

46. Nano-LC-MS/MS for the quantitation of prostanoids in immune cells

Author:
D. Thomas; J. Suo; T. Ulshöfer; H. Jordan; N. de Bruin; K. Scholich; G. Geisslinger; N. Ferreirós
Source:
Analytical and bioanalytical chemistry 2014 v.406 no.28 pp. 7103-7116
ISSN:
1618-2642
Subject:
Food and Drug Administration; T-lymphocytes; arachidonic acid; delayed hypersensitivity; guidelines; immune response; inflammation; mast cells; mice; models; prostaglandins; tandem mass spectrometry; zymosan
Abstract:
... Prostanoids, derivatives of arachidonic acid, are involved in inflammation and immune reactions. To understand the role of prostanoids produced by diverse immune cells, a highly sensitive quantitation method for prostaglandin E₂(PGE₂), prostaglandin D₂(PGD₂), 6-keto prostaglandin F₁α(6-keto PGF₁α), prostaglandin F₂α(PGF₂α), and thromboxane B₂(TXB₂) by means of nano-liquid chromatography-tandem mas ...
DOI:
10.1007/s00216-014-8134-8

47. Nutritional constituents and health benefits of wild rice (Zizania spp.)

Author:
Gangadaran Surendiran; Maha Alsaif; Fatemeh Ramezani Kapourchali; Mohammed H Moghadasian
Source:
Nutrition reviews 2014 v.72 no.4 pp. 227-236
ISSN:
0029-6643
Subject:
Food and Drug Administration; Zizania; antioxidants; dietary fiber; minerals; nutrient content; phytochemicals; starch; vitamins; whole grain foods; wild rice; East Asia; United States
Abstract:
... Wild rice (Zizania spp.) seems to have originated in North America and then dispersed into Eastern Asia and other parts of the world. Nutritional analysis shows that wild rice is rich in minerals, vitamins, protein, starch, dietary fiber, and various antioxidant phytochemicals, while it is low in fat. Wild rice has been recognized as a whole grain by the US Food and Drug Administration; in the Nor ...
DOI:
10.1111/nure.12101
PubMed:
24684371

48. Occurrence of histamine in canned tuna fish from Iran

Author:
Razzagh Mahmoudi; Reza Norian
Source:
Journal für Verbraucherschutz und Lebensmittelsicherheit = 2014 v.9 no.2 pp. 133-136
ISSN:
1661-5751
Subject:
Food and Drug Administration; canned fish; compliance; enzyme-linked immunosorbent assay; histamine; human health and safety; laws and regulations; marine fish; scombroid poisoning; seafoods; spring; summer; trade; tuna; Iran
Abstract:
... Histamine fish poisoning is a significant public health and safety concern and also a trade issue. Histamine was investigated in canned tuna fish in Qazvin province from Iran by ELISA method. Histamine was detected in 29.37 % canned tuna fish samples. The overall mean level of histamine was 8.59 ± 14.24 ppm and the concentration was between 2.51 and 74.56 ppm. Except four samples (2.50 %) of 47 po ...
DOI:
10.1007/s00003-014-0863-2

49. Outbreaks Caused by Sprouts, United States, 1998–2010: Lessons Learned and Solutions Needed

Author:
Dechet Amy M.; Herman Karen M.; Chen Parker Cary; Taormina Peter; Johanson Joy; Tauxe Robert V.; Mahon Barbara E.
Source:
Foodborne pathogens & disease 2014 v.11 no.8 pp. 635-644
ISSN:
1556-7125
Subject:
Food and Drug Administration; Listeria; Salmonella; Shiga toxin-producing Escherichia coli; anti-infective agents; bean sprouts; calcium hypochlorite; chlorination; disinfection; growers; guidelines; human diseases; international cooperation; irrigation water; pathogens; risk; risk reduction; seeds; United States
Abstract:
... After a series of outbreaks associated with sprouts in the mid-1990s, the U.S. Food and Drug Administration (FDA) published guidelines in 1999 for sprouts producers to reduce the risk of contamination. The recommendations included treating seeds with an antimicrobial agent such as calcium hypochlorite solution and testing spent irrigation water for pathogens. From 1998 through 2010, 33 outbreaks f ...
DOI:
10.1089/fpd.2013.1705

50. An Overview of the Recent Developments on Fructooligosaccharide Production and Applications

Author:
Ana Luísa Dominguez; Lígia Raquel Rodrigues; Nelson Manuel Lima; José António Teixeira
Source:
Food and bioprocess technology 2014 v.7 no.2 pp. 324-337
ISSN:
1935-5130
Subject:
Food and Drug Administration; GRAS substances; carcinogenicity; digestive system; enzymes; food industry; functional foods; functional properties; glycemic index; ingredients; intestinal microorganisms; markets; prebiotics; researchers; sweetness; United States
Abstract:
... Over the past years, many researchers have suggested that deficiencies in the diet can lead to disease states and that some diseases can be avoided through an adequate intake of relevant dietary components. Recently, a great interest in dietary modulation of the human gut has been registered. Prebiotics, such as fructooligosaccharides (FOS), play a key role in the improvement of gut microbiota bal ...
DOI:
10.1007/s11947-013-1221-6