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- Nobuo Suzuki; Toshio Sekiguchi; Honoo Satake; Kanoko Kato; Yudai Nishiyama; Hideya Takahashi; Janine A. Danks; T. John Martin; Atsuhiko Hattori; Masaki Nakano; Makiko Kakikawa; Sotoshi Yamada; Maho Ogoshi; Susumu Hyodo; Yoko Yamaguchi; Vishwajit S. Chowdhury; Kazuichi Hayakawa; Hisayuki Funahashi; Tatsuya Sakamoto; Yuichi Sasayama
- Gene 2012 v.499 no.2 pp. 326-331
- Dasyatis; amino acids; animal ovaries; brain; calcitonin; calcitonin receptors; calcium; cartilage; complementary DNA; euryhaline species; flounder; frogs; gall bladder; humans; kidneys; liver; messenger RNA; metabolism; open reading frames; osmoregulation; pancreas; phylogeny; pituitary gland; seawater; spleen; testes
- ... In cartilaginous fish, two cDNAs encoding calcitonin-family receptors were isolated for the first time from the stingray brain. The open reading frame of one receptor cDNA coded a 525-amino acid protein. The amino acid identity of this receptor to human calcitonin-receptor-like receptor (CRLR) is 64.5%, frog CRLR is 64.7%, and flounder CRLR is 61.2% and this was higher than to human calcitonin rec ...
- Wei-Hong Chen; Rong Zeng; Wen-Cheng Lo; Szu-Yu Tina Chen; Tung-Yuan Lai; David F. Williams; Win-Ping Deng
- Biomaterials 2012 v.33 no.33 pp. 8256-8264
- calcitonin; calcitonin receptors; chondrogenesis; cyclic AMP; humans; phenotype; signal transduction; therapeutics
- ... Human disc degeneration initiated by aging in the central nucleus pulposus (hNP) is an irreversible process and the recovery has become seriously emerging. In this study, the related mechanisms of calcitonin on the regeneration of hNP and the effects of calcitonin on the age-related alterations were examined. The harvested hNP population was designated as YhNP (from young donor, age <50) and OhNP ...
- Peter J. Wookey; Kirsty Turner; John B. Furness
- Cell and tissue research 2012 v.347 no.2 pp. 311-317
- calcitonin; calcitonin receptors; colon; esophagus; ganglia; ileum; mice; milk; nerve tissue; neurons; plexus; pregnancy; villi
- ... Calcitonin receptor-immunoreactivity (CTR-ir) was found in enteric neurons of the mouse gastrointestinal tract from embryonic day 13.5 (E13.5) to post-natal day 28 (P28). CTR-ir occurred in cell bodies in ganglia of the myenteric plexus extending from the esophagus to the colon and in nerve cells of the submucosal ganglia of the small and large intestines. CTR-ir was also found in vagal nerve trun ...