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You searched for: Publication Year 2012 Remove constraint Publication Year: 2012 Subject calcitonin receptors Remove constraint Subject: calcitonin receptors Subject term calcitonin receptors Remove constraint Subject term: calcitonin receptors
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1. Cloning of two members of the calcitonin-family receptors from stingray, Dasyatis akajei: Possible physiological roles of the calcitonin family in osmoregulation

Author:
Nobuo Suzuki; Toshio Sekiguchi; Honoo Satake; Kanoko Kato; Yudai Nishiyama; Hideya Takahashi; Janine A. Danks; T. John Martin; Atsuhiko Hattori; Masaki Nakano; Makiko Kakikawa; Sotoshi Yamada; Maho Ogoshi; Susumu Hyodo; Yoko Yamaguchi; Vishwajit S. Chowdhury; Kazuichi Hayakawa; Hisayuki Funahashi; Tatsuya Sakamoto; Yuichi Sasayama
Source:
Gene 2012 v.499 no.2 pp. 326-331
ISSN:
0378-1119
Subject:
Dasyatis; amino acids; animal ovaries; brain; calcitonin; calcitonin receptors; calcium; cartilage; complementary DNA; euryhaline species; flounder; frogs; gall bladder; humans; kidneys; liver; messenger RNA; metabolism; open reading frames; osmoregulation; pancreas; phylogeny; pituitary gland; seawater; spleen; testes
Abstract:
... In cartilaginous fish, two cDNAs encoding calcitonin-family receptors were isolated for the first time from the stingray brain. The open reading frame of one receptor cDNA coded a 525-amino acid protein. The amino acid identity of this receptor to human calcitonin-receptor-like receptor (CRLR) is 64.5%, frog CRLR is 64.7%, and flounder CRLR is 61.2% and this was higher than to human calcitonin rec ...
DOI:
10.1016/j.gene.2012.03.042
PubMed:
22429839

2. Transient expression of the calcitonin receptor by enteric neurons of the embryonic and early post-natal mouse

Author:
Peter J. Wookey; Kirsty Turner; John B. Furness
Source:
Cell and tissue research 2012 v.347 no.2 pp. 311-317
ISSN:
0302-766X
Subject:
calcitonin; calcitonin receptors; colon; esophagus; ganglia; ileum; mice; milk; nerve tissue; neurons; plexus; pregnancy; villi
Abstract:
... Calcitonin receptor-immunoreactivity (CTR-ir) was found in enteric neurons of the mouse gastrointestinal tract from embryonic day 13.5 (E13.5) to post-natal day 28 (P28). CTR-ir occurred in cell bodies in ganglia of the myenteric plexus extending from the esophagus to the colon and in nerve cells of the submucosal ganglia of the small and large intestines. CTR-ir was also found in vagal nerve trun ...
DOI:
10.1007/s00441-011-1303-6
PubMed:
22271140

3. The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus

Author:
Wei-Hong Chen; Rong Zeng; Wen-Cheng Lo; Szu-Yu Tina Chen; Tung-Yuan Lai; David F. Williams; Win-Ping Deng
Source:
Biomaterials 2012 v.33 no.33 pp. 8256-8264
ISSN:
0142-9612
Subject:
calcitonin; calcitonin receptors; chondrogenesis; cyclic AMP; humans; phenotype; signal transduction; therapeutics
Abstract:
... Human disc degeneration initiated by aging in the central nucleus pulposus (hNP) is an irreversible process and the recovery has become seriously emerging. In this study, the related mechanisms of calcitonin on the regeneration of hNP and the effects of calcitonin on the age-related alterations were examined. The harvested hNP population was designated as YhNP (from young donor, age <50) and OhNP ...
DOI:
10.1016/j.biomaterials.2012.06.088