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You searched for: Publication Year 2012 Remove constraint Publication Year: 2012 Subject term arteries Remove constraint Subject term: arteries
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1. 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside Inhibits Proliferation of Vascular Smooth Muscle Cells: Involvement of NO/cGMP/PKG Pathway

Author:
Xiao‐Le Xu; Yan‐Juan Huang; Xiang‐Fan Chen; Dan‐Yan Lin; Wei Zhang
Source:
Phytotherapy research 2012 v.26 no.7 pp. 1068-1074
ISSN:
0951-418X
Subject:
cGMP-dependent protein kinase; atherosclerosis; growth factors; nitric oxide; smooth muscle; DNA; cyclic GMP; guanylate cyclase; flow cytometry; myocytes; cell proliferation; arteries; cell cycle; Reynoutria multiflora
Abstract:
... The proliferation of vascular smooth muscle cells (VSMCs) induced by injury to the intima of arteries is an important etiologic factor in vascular proliferative disorders such as atherosclerosis and restenosis. 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside (TSG), an active component extracted from Polygonum multiflorum, has been found to have an antiatherosclerotic effect. The aim of this study ...
DOI:
10.1002/ptr.3691
PubMed:
22213189

2. Acute, quercetin-induced reductions in blood pressure in hypertensive individuals are not secondary to lower plasma angiotensin-converting enzyme activity or endothelin-1: nitric oxide

Author:
Abigail Larson; Melissa A.H. Witman; Yi Guo; Stephen Ives; Russell S. Richardson; Richard S. Bruno; Thunder Jalili; J. David Symons
Source:
Nutrition research 2012 v.32 no.8 pp. 557-564
ISSN:
0271-5317
Subject:
arteries; bioavailability; blood pressure; enzyme activity; men; nitric oxide; nitrites; peptidyl-dipeptidase A; placebos; quercetin
Abstract:
... Quercetin (Q) reduces blood pressure (BP) in hypertensive individuals, but the mechanism is unknown. We hypothesized that acute Q aglycone administration reduces BP in hypertensive men by decreasing angiotensin-converting enzyme (ACE) activity and/or by lowering the ratio of circulating endothelin-1 (ET-1) to nitric oxide and that these alterations will improve endothelial function. Using a double ...
DOI:
10.1016/j.nutres.2012.06.018
PubMed:
22935338

3. Agreement between direct, oscillometric and Doppler ultrasound blood pressures using three different cuff positions in anesthetized dogs

Author:
Natache A Garofalo; Francisco J Teixeira Neto; Renata K Alvaides; Flávia A de Oliveira; Wangles Pignaton; Renato T Pinheiro
Source:
Veterinary anaesthesia and analgesia 2012 v.39 no.4 pp. 324-334
ISSN:
1467-2987
Subject:
adults; arteries; carpus; catheters; dogs; dopamine; hypertension; hypotension; isoflurane; monitoring; prospective studies; systolic blood pressure; ultrasonics
Abstract:
... Objective To evaluate the agreement between invasive blood pressure (IBP) and Doppler ultrasound blood pressure (DUBP) using three cuff positions and oscillometric blood pressure (OBP) in anesthetized dogs. Study design Prospective study. Animals Nine adult dogs weighing 14.5–29.5 kg. Methods The cuff was placed above and below the tarsus, and above the carpus with the DUBP and above the carpus wi ...
DOI:
10.1111/j.1467-2995.2012.00711.x
PubMed:
22414262

4. Altered adipocyte progenitor population and adipose-related gene profile in adipose tissue by long-term high-fat diet in mice

Author:
Xiaohua Xu; Cuiqing Liu; Zhaobin Xu; Kevin Tzan; Aixia Wang; Sanjay Rajagopalan; Qinghua Sun
Source:
Life sciences 2012 v.90 no.25-26 pp. 1001-1009
ISSN:
0024-3205
Subject:
adipocytes; adiponectin; arteries; gene expression; genes; glucose; glucose tolerance tests; high fat diet; hyperplasia; hypertrophy; inflammation; insulin resistance; long term effects; metabolism; mice; obesity; stem cells; white adipose tissue
Abstract:
... AIMS: High-fat diet (HFD) is associated with adipose inflammation, which contributes to key components of metabolic abnormalities. The expanded adipose tissue mass associated with obesity is the result of hyperplasia and hypertrophy of adipocytes. In this study, we investigated the effects of long-term HFD on adipocyte progenitor cell (APC) population and adipose-specific gene profiles in both whi ...
DOI:
10.1016/j.lfs.2012.05.016
PubMed:
22683431
PubMed Central:
PMC3390972

5. Anatomical Relationship Between the Collecting System and the Intrarenal Arteries in the Rabbit: Contribution for an Experimental Model

Author:
A. Shalgum; B. P. S. Marques‐Sampaio; A. Dafalla; M. A. Pereira‐Sampaio
Source:
Anatomia, histologia, embryologia 2012 v.41 no.2 pp. 130-138
ISSN:
0340-2096
Subject:
arteries; humans; kidneys; models; rabbits
Abstract:
... With 6 figures and 2 tables SUMMARY: Intrarenal anatomy was studied in detail to evaluate how useful rabbits could be as a urologic model. Only one renal artery was observed, which was divided into dorsal and ventral branches in all cases. Three segmental arteries (cranial, mesorenal and caudal) was the most frequent branching pattern found in both the dorsal and ventral division. There was an imp ...
DOI:
10.1111/j.1439-0264.2011.01112.x
PubMed:
22017266

6. Arteriolar vascular smooth muscle cells: Mechanotransducers in a complex environment

Author:
Michael A. Hill; Gerald A. Meininger
Source:
international journal of biochemistry & cell biology 2012 v.44 no.9 pp. 1505-1510
ISSN:
1357-2725
Subject:
arteries; blood flow; calcium; cell membranes; cytoskeleton; deformation; extracellular matrix; integrins; ion channels; mechanotransduction; myocytes; receptors; smooth muscle
Abstract:
... Contraction of small artery (diameters typically less than 250μm) vascular smooth muscle cells (VSMCs) plays a critical role in local control of blood flow and arterial pressure through its affect on vascular caliber. Specifically, contraction of small arteries in response to increased intraluminal pressure is referred to as the myogenic response and represents an important role for mechanotransdu ...
DOI:
10.1016/j.biocel.2012.05.021
PubMed:
22677491
PubMed Central:
PMC4221252

7. Blood Flow Characteristics of the Human Lactating Breast

Author:
Donna T. Geddes; Khalidah M. Aljazaf; Jacqueline C. Kent; Danielle K. Prime; Diane L. Spatz; Catherine P. Garbin; Ching Tat Lai; Peter E. Hartmann
Source:
Journal of human lactation 2012 v.28 no.2 pp. 145-152
ISSN:
0890-3344
Subject:
arteries; blood flow; breast milk; breasts; lactating women; lactation; milk production; milk synthesis; ultrasonics
Abstract:
... BACKGROUND: Despite the increased metabolic activity of the lactating breast, no studies have been carried out to determine mammary blood flow (MBF) parameters or the relationship between MBF and milk production in women. The aim of this study was to measure the MBF in the internal mammary artery (IMA) and lateral thoracic artery (LTA) of lactating women and determine if these were related to milk ...
DOI:
10.1177/0890334411435414
PubMed:
22526342

8. Catalysis-Based Inhibitors of the Calcium Signaling Function of CD38

Author:
Kwong Anna KaYee; Chen Zhe; Zhang HongMin; Leung Fung Ping; Lam Connie Mo Ching; Ting Kai Yiu; Zhang Liangren; Hao Quan; Zhang Li-He; Lee Hon Cheung
Source:
Biochemistry 2012 v.51 no.1 pp. 555-564
ISSN:
1520-4995
Subject:
X-ray diffraction; adenosine diphosphate; arteries; calcium; calcium signaling; esterases; genes; humans; mesentery; mice; oxytocin; rats; retinoic acid; ribose; social behavior; structure-activity relationships
Abstract:
... CD38 is a signaling enzyme responsible for catalyzing the synthesis of cyclic ADP ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate; both are universal Ca²⁺ messenger molecules. Ablation of the CD38 gene in mice causes multiple physiological defects, including impaired oxytocin release, that result in altered social behavior. A series of catalysis-based inhibitors of CD38 were desig ...
DOI:
10.1021/bi201509f

9. Comparison of direct and Doppler arterial blood pressure measurements in rabbits during isoflurane anaesthesia

Author:
Louise Harvey; Toby Knowles; Pamela J Murison
Source:
Veterinary anaesthesia and analgesia 2012 v.39 no.2 pp. 174-184
ISSN:
1467-2987
Subject:
anesthesia; arteries; blood pressure; carpus; castration; catheters; forelimbs; hypotension; isoflurane; monitoring; prospective studies; rabbits
Abstract:
... Objective To measure the level of agreement between Doppler measured (DOP) arterial blood pressure (ABP) in the forelimb and directly measured (DIR) auricular systolic ABP (SAP) and mean ABP (MAP) in isoflurane‐anaesthetized rabbits. Study design Prospective clinical study. Animals Data were analysed from 17 of 24 healthy rabbits, weighing 1.3–2.8 kg. Methods Rabbits were anaesthetized for neuteri ...
DOI:
10.1111/j.1467-2995.2011.00685.x
PubMed:
22356416

10. Compressive Myelopathy Associated With Ectasia of the Vertebral and Spinal Arteries in a Dog

Author:
C. C. Bozynski; L. Vasquez; D. P. O’Brien; G. C. Johnson
Source:
Veterinary pathology v.49 no.5 pp. 779-783
ISSN:
1544-2217
Subject:
animal pathology; arteries; cervical spine; dogs; fibrosis; hemorrhage; magnetic resonance imaging; necropsy; nerve tissue; spinal cord; thrombosis
Abstract:
... A 4-year-old dog was presented for acute, progressive tetraparesis and cervical hyperesthesia. Symmetrical tubular structures coursing along the lateroventral aspects of the spinal cord at the fourth and fifth cervical vertebrae were identified in magnetic resonance images. At necropsy, vertebral arteries and their spinal branches were severely ectatic bilaterally, and the cervical spinal cord was ...
DOI:
10.1177/0300985811415704

11. Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling

Author:
Linda Chang; Michela Noseda; Michelle Higginson; Michelle Ly; Alexandre Patenaude; Megan Fuller; Alastair H. Kyle; Andrew I. Minchinton; Mira C. Puri; Daniel J. Dumont; Aly Karsan
Source:
Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.18 pp. 6993-6998
ISSN:
0027-8424
Subject:
adults; arteries; embryogenesis; hemorrhage; mice; myocytes; smooth muscle; stem cells
Abstract:
... Vascular smooth muscle cells (VSMC) have been suggested to arise from various developmental sources during embryogenesis, depending on the vascular bed. However, evidence also points to a common subpopulation of vascular progenitor cells predisposed to VSMC fate in the embryo. In the present study, we use binary transgenic reporter mice to identify a Tie1+CD31dimvascular endothelial (VE)-cadherin– ...
DOI:
10.1073/pnas.1118512109
PubMed:
22509029
PubMed Central:
PMC3345008

12. Doppler sonography of the uterine and ovarian arteries during a superovulatory program in horses

Author:
M.C. Witt; H. Bollwein; J. Probst; C. Baackmann; E.L. Squires; H. Sieme
Source:
Theriogenology 2012 v.77 no.7 pp. 1406-1414
ISSN:
0093-691X
Subject:
animal ovaries; arteries; blood flow; correlation; estrogens; follicular development; human chorionic gonadotropin; insemination; mares; ovulation; progesterone; steroid hormones; superovulation
Abstract:
... The aim of the present study was to investigate the effects of a gonadotropin treatment to induce superovulation on ovarian and uterine blood flow and its relationship with steroid hormone levels and ovarian response in mares, using color Doppler sonography. Each of six mares were examined sonographically in five cycles for 3 d (t1 to t3) during the follicular development phase (FDP) beginning at ...
DOI:
10.1016/j.theriogenology.2011.11.005
PubMed:
22196623

13. Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Author:
Ismaila A. Raji; Pierre Mugabo; Kenechukwu Obikeze
Source:
Journal of ethnopharmacology 2012 v.140 no.1 pp. 98-106
ISSN:
0378-8741
Subject:
Tulbaghia; acetates; adrenergic receptors; angiotensin I; angiotensin II; arteries; blood pressure; enzymes; heart rate; humans; intravenous injection; leaf extracts; males; methanol; phenylephrine; rats; salts
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Tulbaghia violacea Harv. (Alliaceae) is a small bulbous herb which belongs to the family Alliaceae, most commonly associated with onions and garlic. In South Africa, this herb has been traditionally used in the treatment of various ailments, including fever, colds, asthma, paralysis, hypertension and stomach problems. The aim of this study was to evaluate the effect ...
DOI:
10.1016/j.jep.2011.12.034
PubMed:
22222281

14. Effects of FSH and LH on ovarian and follicular blood flow, follicular growth and oocyte developmental competence in young and old mares

Author:
J.L. Altermatt; A.J. Marolf; R.H. Wrigley; E.M. Carnevale
Source:
Animal reproduction science 2012 v.133 no.3-4 pp. 191-197
ISSN:
0378-4320
Subject:
animal ovaries; arteries; blastocyst; blood flow; color; elderly; follicle-stimulating hormone; luteinizing hormone; mares; oocytes; pregnancy; spermatozoa; ultrasonography
Abstract:
... Objectives of the experiment were to determine the effects of mare age and gonadotropin treatments on dominant follicle vascularity, ovarian blood flow and dominant follicle growth and to associate follicular vascularity with oocyte developmental capacity. Growing follicles >30mm from young (4–9 years) and old (>20 years) mares were assessed for blood flow using color Doppler ultrasonography befor ...
DOI:
10.1016/j.anireprosci.2012.06.021

15. Endothelin-1 and -2: Two amino acids matter

Author:
Matthijs G. Compeer; Dennis P.L. Suylen; Tilman M. Hackeng; Jo G.R. De Mey
Source:
Life sciences 2012 v.91 no.13-14 pp. 607-612
ISSN:
0024-3205
Subject:
agonists; amino acids; antagonists; arteries; chimerism; endothelium; nerve tissue; rats; receptors; smooth muscle
Abstract:
... AIMS: Endothelin-1 (ET-1) and endothelin-2 (ET-2; Trp⁶Leu⁷ET-1) are expressed by different cell types, but are considered to display identical pharmacological properties on endothelin receptors. We studied agonist-dependent aspects of endothelinA (ETA)-receptor function and the importance of amino acids 6 and 7 of ET-1 and ET-2 in this respect. MAIN METHODS: We used isolated rat mesenteric resista ...
DOI:
10.1016/j.lfs.2012.02.011

16. Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict

Author:
Robert M. Samstein; Steven Z. Josefowicz; Aaron Arvey; Piper M. Treuting; Alexander Y. Rudensky
Source:
Cell 2012 v.150 no.1 pp. 29-38
ISSN:
0092-8674
Subject:
T-lymphocytes; arteries; autoimmunity; evolution; females; fetal resorption; males; mammals; placenta; pregnancy; thymus gland; transcription factors
Abstract:
... Regulatory T (Treg) cells, whose differentiation and function are controlled by X chromosome-encoded transcription factor Foxp3, are generated in the thymus (tTreg) and extrathymically (peripheral, pTreg), and their deficiency results in fatal autoimmunity. Here, we demonstrate that a Foxp3 enhancer, conserved noncoding sequence 1 (CNS1), essential for pTreg but dispensable for tTreg cell generati ...
DOI:
10.1016/j.cell.2012.05.031
PubMed:
22770213
PubMed Central:
PMC3422629

17. Histological evidence: housekeeping genes beta-actin and GAPDH are of limited value for normalization of gene expression

Author:
Juntang Lin; Christoph Redies
Source:
Development genes and evolution 2012 v.222 no.6 pp. 369-376
ISSN:
0949-944X
Subject:
Northern blotting; Western blotting; actin; arteries; cardiomyocytes; chickens; digestive tract; embryogenesis; essential genes; gene expression; gizzard; in situ hybridization; liver; messenger RNA; reverse transcriptase polymerase chain reaction
Abstract:
... Housekeeping genes are widely used as internal controls for gene expression normalization for western blotting, northern blotting, RT-PCR, etc. They are generally thought to be expressed in all cells of the organism at similar levels because it is assumed that these genes are required for the maintenance of basic cellular function as constitutive genes. However, real-time RT-PCR experiments reveal ...
DOI:
10.1007/s00427-012-0420-x
PubMed:
23099774

18. Histological examination of vascular lesions caused by stent implantation in humans and in comparative experimental animal model

Author:
G. Kasza; L. Kollár; Erzsébet Rőth; A. Vincze; Éva Gömöri
Source:
Acta biologica Hungarica 2012 v.63 no.1 pp. 1-14
ISSN:
0236-5383
Subject:
animal models; arteries; cell proliferation; dogs; humans; immunohistochemistry; tissues
Abstract:
... A comparative analysis of human and experimental animal (canine) tissues was performed to characterize and describe cellular and histological responses during the processes of newly forming intravascular tissues after stent implantation. Routine histological and immunohistochemical evaluation of 20 human samples and 9 samples from animal models were used one day, one week and one month after the s ...
DOI:
10.1556/ABiol.63.2012.1.1

19. Human cytomegalovirus infection inhibits CXCL12- mediated migration and invasion of human extravillous cytotrophoblasts

Author:
Jessica A Warner; Kevin J Zwezdaryk; Bonita Day; Deborah E Sullivan; Gabriella Pridjian; Cindy A Morris
Source:
Virology journal 2012 v.9 no.1 pp. 255
ISSN:
1743-422X
Subject:
CXCR4 receptor; abortion (animals); animal viruses; arteries; atypical chemokine receptor 3; cell lines; chemokine CXCL12; congenital abnormalities; epidermal growth factor; hepatocyte growth factor; humans; invasive species; messenger RNA; mitogens; pre-eclampsia; pregnancy; secretion; signal transduction; trophoblast; viruses
Abstract:
... BACKGROUND: During the first trimester of pregnancy, a series of tightly regulated interactions govern the formation of a highly invasive population of fetal-derived extravillous cytotrophoblasts (EVT). Successful pregnancy is dependent on efficient invasion of the uterine wall and maternal spiral arteries by EVT. Dysregulated trophoblast invasion is associated with intrauterine growth restriction ...
DOI:
10.1186/1743-422X-9-255

20. Identification of orexins and cognate receptors in the lacrimal gland of sheep

Author:
Cecilia Dall’Aglio; Francesca Mercati; Margherita Maranesi; Cristiano Boiti
Source:
Peptides 2012 v.35 no.1 pp. 36-41
ISSN:
0196-9781
Subject:
arteries; cytoplasm; gene expression; genes; immunohistochemistry; lacrimal apparatus; receptors; reverse transcriptase polymerase chain reaction; sheep
Abstract:
... The aim of the present work was to study, by means of immunohistochemical and RT-PCR techniques, the presence and distribution of immunopositivity for orexin A and B (OXA and OXB) and orexin type 1 and 2 receptors (OX₁R and OX₂R) in the lacrimal gland of sheep as well as the gene expressions for prepro-orexin (PPOX) and cognate receptors. In serial sections, positive staining for OXA and OXB were ...
DOI:
10.1016/j.peptides.2012.03.012

21. Influence of a constant rate infusion of dexmedetomidine on cardiopulmonary function and recovery quality in isoflurane anaesthetized horses

Author:
Miguel G Marcilla; Stijn Schauvliege; Stefanie Segaert; Luc Duchateau; Frank Gasthuys
Source:
Veterinary anaesthesia and analgesia 2012 v.39 no.1 pp. 49-58
ISSN:
1467-2987
Subject:
adults; air; anesthesia; arteries; blood pressure; carbon dioxide; cardiac output; clinical trials; dexmedetomidine; heart rate; hematocrit; horses; hypotension; intravenous injection; isoflurane; ketamine; monitoring; oxygen; prospective studies; sedation; surgery
Abstract:
... Objective To investigate the influence of a dexmedetomidine constant rate infusion (CRI) in horses anaesthetized with isoflurane. Study design Prospective, randomized, blinded, clinical study. Animals Forty adult healthy horses (weight mean 491 ± SD 102 kg) undergoing elective surgery. Methods After sedation [dexmedetomidine, 3.5 μg kg−1 intravenously (IV)] and induction IV (midazolam 0.06 mg kg−1 ...
DOI:
10.1111/j.1467-2995.2011.00672.x
PubMed:
22151875

22. Long-term facial artery catheter implantation for serial arterial blood sampling and invasive arterial blood pressure measurement in horses

Author:
Deborah Penteado Martins Dias; Luisa Gouvêa Teixeira; Paulo Aléscio Canola; Raquel Mincarelli Albernaz; José Antônio Marques; José Corrêa de Lacerda Neto
Source:
veterinary journal 2012 v.192 no.3 pp. 541-543
ISSN:
1090-0233
Subject:
arteries; ascorbic acid; blood; blood pressure; blood sampling; catheters; exercise; exercise test; heparin; horses; polyurethanes
Abstract:
... The purpose of this investigation was to evaluate surgical catheter implantation in the facial artery of horses and the long-term maintenance of such arteries using heparin and ascorbic acid as filling solution. Nine horses were implanted with a polyurethane catheter. The catheters were flushed with a heparin/ascorbic acid solution every 8h and remained patent for 25days. Arterial blood samples we ...
DOI:
10.1016/j.tvjl.2011.06.031

23. Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis

Author:
Peng Li; Mohammad Pashmforoush; Henry M. Sucov
Source:
Developmental biology 2012 v.361 no.1 pp. 116-124
ISSN:
0012-1606
Subject:
abnormal development; arteries; endothelial cells; endothelium; mice; models; morphogenesis; mutants; mutation; pouches; retinoic acid; signal transduction
Abstract:
... Disruption of retinoic acid signaling causes a variety of pharyngeal arch artery and great vessel defects, as well as malformations in many other tissues, including those derived from the pharyngeal endoderm. Previous studies implied that arch artery defects in the context of defective RA signaling occur secondary to pharyngeal pouch segmentation defects, although this model has never been experim ...
DOI:
10.1016/j.ydbio.2011.10.018
PubMed:
22040871
PubMed Central:
PMC3235035

24. Myocardial Toxicity in a Group of Greyhounds Administered Ractopamine

Author:
M. J. Yaeger; K. Mullin; S. M. Ensley; W. A. Ware; R. E. Slavin
Source:
Veterinary pathology v.49 no.3 pp. 569-573
ISSN:
1544-2217
Subject:
Greyhound; agonists; arrhythmia; arteries; body fat; cattle; dogs; feed additives; muscles; necrosis; oral administration; racing animals; skeletal muscle; swine; toxicity; turkeys; urine; United States
Abstract:
... Ractopamine, a synthetic β₂-adrenoceptor agonist, is widely used as a feed additive in the United States to promote a reduction in body fat and enhance muscle growth in cattle, pigs, and turkeys. It has the potential for illegal use in show and racing animals because it may affect performance via its β-adrenergic agonist properties or anabolic activities. Nine greyhounds were orally administered 1 ...
DOI:
10.1177/0300985811424752
PubMed:
21997565

25. Negative blood oxygenation level dependent homunculus and somatotopic information in primary motor cortex and supplementary motor area

Author:
Noa Zeharia; Uri Hertz; Tamar Flash; Amir Amedi
Source:
Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.45 pp. 18565-18570
ISSN:
0027-8424
Subject:
arteries; blood; cortex; dissociation; image analysis; muscles; prediction
Abstract:
... A crucial attribute in movement encoding is an adequate balance between suppression of unwanted muscles and activation of required ones. We studied movement encoding across the primary motor cortex (M1) and supplementary motor area (SMA) by inspecting the positive and negative blood oxygenation level-dependent (BOLD) signals in these regions. Using periodic and event-related experiments incorporat ...
DOI:
10.1073/pnas.1119125109
PubMed:
23086164
PubMed Central:
PMC3494917

26. Periparturient Arterial Rupture in Mares: A Postmortem Study

Author:
Neil M. Williams; Uneeda K. Bryant
Source:
Journal of equine veterinary science 2012 v.32 no.5 pp. 281-284
ISSN:
0737-0806
Subject:
arteries; mares; necropsy; parturition; pregnancy; universities; Kentucky
Abstract:
... There are limited reports characterizing the occurrence of rupture of uterine and other arteries associated with pregnancy in mares. Cases were retrieved from the records of horses submitted for necropsy to the University of Kentucky Veterinary Diagnostic Laboratory over a 15-year period (1993-2007). Five hundred thirteen horses were diagnosed with periparturient arterial rupture, representing 1.5 ...
DOI:
10.1016/j.jevs.2011.11.002

27. Peripheral and central alterations of pituitary adenylate cyclase activating polypeptide-like immunoreactivity in the rat in response to activation of the trigeminovascular system

Author:
Bernadett Tuka; Zsuzsanna Helyes; Adrienn Markovics; Teréz Bagoly; József Németh; László Márk; Réka Brubel; Dóra Reglődi; Árpád Párdutz; János Szolcsányi; László Vécsei; János Tajti
Source:
Peptides 2012 v.33 no.2 pp. 307-316
ISSN:
0196-9781
Subject:
adenylate cyclase; animal models; arteries; cerebrospinal fluid; electrical treatment; ganglia; headache; mass spectrometry; polypeptides; radioimmunoassays; rats; sensory neurons; spinal cord
Abstract:
... Pituitary adenylate cyclase activating polypeptide (PACAP) is present in the cranial arteries and trigeminal sensory neurons. We therefore examined the alterations in PACAP-like immunoreactivity (PACAP-LI) in a time-dependent manner in two rat models of trigeminovascular system (TS) activation. In one group chemical stimulation (CS) was performed with i.p. nitroglycerol (NTG), and in the other one ...
DOI:
10.1016/j.peptides.2011.12.019

28. Post-implant evaluation of the anastomotic mechanical and geometrical coupling between human native arteries and arterial cryografts implanted in lower-limb Mechanical, histological and ultraestructural studies of implanted cryografts

Author:
Daniel Bia; Yanina Zócalo; Ricardo L. Armentano; Héctor Pérez-Cámpos; Juan Fernández-Pin; Ana Panuncio; María Saldías; Ana Mariño; Inés Álvarez
Source:
Cryobiology 2012 v.64 no.1 pp. 50-59
ISSN:
0011-2240
Subject:
polytetrafluoroethylene; humans; cryopreservation; prostheses; modulus of elasticity; mechanical properties; functional properties; arteries
Abstract:
... BACKGROUND: There is an urgent need of vascular substitutes (VS) to be used in lower limb revascularization procedures when autologous veins are not available and synthetic prosthesis are contraindicated. Since the mechanical differences with respect to native vessels are determinants of the VS failure, the substitutes should have mechanical properties similar to those of the recipient vessels. Th ...
DOI:
10.1016/j.cryobiol.2011.09.133

29. Pre-anaesthetic metomidate sedation delays the stress response after caudal artery cannulation in Atlantic cod (Gadus morhua)

Author:
Anders Karlsson; Bjørn Olav Rosseland; Jean-Charles Massabuau; Anders Kiessling
Source:
Fish physiology and biochemistry 2012 v.38 no.2 pp. 401-411
ISSN:
0920-1742
Subject:
Gadus morhua; arteries; blood glucose; blood sampling; cannulas; cod (fish); cortisol; electrolytes; glucose; pH; sedation; stress response; surgery
Abstract:
... Recovery from caudal artery cannulation with and without pre-anaesthesia metomidate sedation was assessed in Atlantic cod (Gadus morhua). The levels of plasma cortisol, glucose, electrolytes and acid–base parameters were compared between sedated and unsedated cod and to those in uncannulated individuals, where the samples were obtained by sacrificial sampling (reference level). Metomidate sedation ...
DOI:
10.1007/s10695-011-9516-x
PubMed:
21638007

30. Relationship Between Aortic Mineral Elements and Osteodystrophy in Mice with Chronic Kidney Disease

Author:
Takeshi Matsumoto; Shuichiro Fukushima; Takeshi Kanasaki; Shingo Hagino
Source:
Biological trace element research 2012 v.150 no.1-3 pp. 278-284
ISSN:
0163-4984
Subject:
arteries; blood; calcification; calcium; hyperparathyroidism; kidney diseases; magnesium; mice; micro-computed tomography; spectroscopy; vertebrae
Abstract:
... In chronic kidney disease (CKD), osteodystrophy and arterial calcification often coexist. However, arterial alterations have not been addressed in CKD unaccompanied by evidence of calcification. We investigated the association of phosphate (P) and calcium (Ca) accumulation in calcification-free aortas with CKD-induced osteodystrophy. Aortic accumulation of magnesium (Mg), an inhibitor of calcifica ...
DOI:
10.1007/s12011-012-9466-x
PubMed:
22700181

31. Remarks on the seasonal occurrence and identification of young plasmodial stages of Myxobolus spp. Infecting cyprinid fishes in Hungary

Author:
Kálmán Molnár; Gábor Cech; Csaba Székely
Source:
Acta veterinaria Hungarica 2012 v.60 no.1 pp. 69-82
ISSN:
0236-6290
Subject:
Leuciscus idus; Myxobolus; Rutilus rutilus; arteries; developmental stages; fish; nucleotide sequences; ribosomal DNA; seasonal variation; spores; spring; summer; surveys; Hungary
Abstract:
... During a survey on the Myxobolus infection of two cyprinid fishes, the ide (Leuciscus idus) and the roach (Rutilus rutilus), myxosporean developmental stages were found around the arteries of the gill filaments and in the gill lamellae. An analysis of the 18S rDNA sequences of these stages revealed that plasmodia developing in the ide belonged to Myxobolus elegans, thos ...
DOI:
10.1556/AVet.2012.006

32. Strongylus vulgaris (Looss, 1900) in horses in Italy: Is it still a problem?

Author:
C. Pilo; A. Altea; S. Pirino; P. Nicolussi; A. Varcasia; M. Genchi; A. Scala
Source:
Veterinary parasitology 2012 v.184 no.2-4 pp. 161-167
ISSN:
0304-4017
Subject:
Strongylus vulgaris; albumins; anthelmintics; arteries; colic; erythrocytes; farms; globulins; histology; horses; larvae; parasites; surveys; Italy
Abstract:
... A post-mortem survey was carried out on 46 Sardinian horses to evaluate the presence of Strongylus vulgaris and associated pathology. Horses were from local farms and had been treated with broad-spectrum anthelmintics at least 3 times a year. Examination of the cranial mesenteric arterial system (CMAS) showed parasite-induced lesions in all horses. S. vulgaris larvae were found in 39% of examined ...
DOI:
10.1016/j.vetpar.2011.09.016
PubMed:
21962966

33. Tomato paste supplementation improves endothelial dynamics and reduces plasma total oxidative status in healthy subjects

Author:
Panagiotis Xaplanteris; Charalambos Vlachopoulos; Panagiota Pietri; Dimitrios Terentes-Printzios; Despina Kardara; Nikolaos Alexopoulos; Konstantinos Aznaouridis; Antigoni Miliou; Christodoulos Stefanadis
Source:
Nutrition research 2012 v.32 no.5 pp. 390-394
ISSN:
0271-5317
Subject:
tomatoes; peroxides; blood lipids; diet study techniques; analysis of variance; normal values; women; lycopene; enzyme-linked immunosorbent assay; volunteers; arteries; tomato paste; ultrasonography
Abstract:
... Consumption of tomato products is linked to beneficial outcomes through antioxidant and anti-inflammatory mechanisms. The aim of this study was to determine whether a 14-day period of tomato paste supplementation would improve endothelial function. Nineteen volunteers (mean age, 39 ± 13 years; 8 men/11 women) were studied in a randomized (exposure sequence), single-blind (operator), crossover desi ...
DOI:
10.1016/j.nutres.2012.03.011
PubMed:
22652379

34. Transforming growth factor-β and atherosclerosis: interwoven atherogenic and atheroprotective aspects

Author:
Ian Toma; Timothy A. McCaffrey
Source:
Cell and tissue research 2012 v.347 no.1 pp. 155-175
ISSN:
0302-766X
Subject:
apoptosis; arteries; atherogenesis; atherosclerosis; calcification; cell movement; cell proliferation; chemotaxis; fibrosis; immune response; inflammation; mitogen-activated protein kinase; myocardial infarction; risk factors; stroke; thrombosis; tissue repair; transforming growth factor beta; United States
Abstract:
... Age-related progression of cardiovascular disease is by far the largest health problem in the US and involves vascular damage, progressive vascular fibrosis and the accumulation of lipid-rich atherosclerotic lesions. Advanced lesions can restrict flow to key organs and can trigger occlusive thrombosis resulting in a stroke or myocardial infarction. Transforming growth factor-beta (TGF-β) is a majo ...
DOI:
10.1007/s00441-011-1189-3
PubMed:
21626289
PubMed Central:
PMC4915479

35. Vasorelaxant effect of isoquinoline derivatives from two species of Popowia perakensis and Phaeanthus crassipetalus on rat aortic artery

Author:
Kazumasa Zaima; Yuka Takeyama; Ikumi Koga; Aiko Saito; Haruka Tamamoto; Saripah Salbiah Syed Abd. Azziz; Mat Ropi Mukhtar; Khalijah Awang; A. Hamid A. Hadi; Hiroshi Morita
Source:
Natural medicines 2012 v.66 no.3 pp. 421-427
ISSN:
1340-3443
Subject:
arteries; calcium; endothelial cells; isoquinoline alkaloids; isoquinolines; nitric oxide; phenylephrine; rats
Abstract:
... Five bisbenzyl isoquinolines (1–5), three benzyl isoquinolines (6–8), four isoquinoline alkaloids (9–12), and two unclassified compounds (13 and 14) from Popowia perakensis and Phaeanthus crassipetalus were evaluated for their vasorelaxant effect on rat aortic arteries. In aortic rings pre-contracted with phenylephrine (PE, 0.3 μM), some of the bisbenzyl isoquinoline alkaloids, benzyl isoquinoline ...
DOI:
10.1007/s11418-011-0600-4
PubMed:
22033647

36. A bilayer prototype woven vascular prosthesis with improved radial compliance

Author:
Ying Chen; Xin Ding; Yuling Li; Martin W. King; Jie Gao; Xueqian Zhao
Source:
The journal of the Textile Institute 2012 v.103 no.1 pp. 106-111
ISSN:
1754-2340
Subject:
arteries; biomimetics; blood pressure; ethylene; polyethylene terephthalates; prostheses; yarns
Abstract:
... To minimize radial compliance mismatch between native arteries and vascular prostheses over the entire blood pressure range, a biomimetic woven prosthesis sample with a bilayer wall has been developed. Poly(trimethylene terephthalate) (PTT) filaments were used as the circumferential yarns in the inner layer to increase the radial compliance of the inner wall, and poly(ethylene terephthalate) (PET) ...
DOI:
10.1080/00405000.2011.552956

37. The effect of endothelin receptor A antagonism on basilar artery endothelium-dependent relaxation after ischemic stroke

Author:
Maha Coucha; Weiguo Li; Adviye Ergul
Source:
Life sciences 2012 v.91 no.13-14 pp. 676-680
ISSN:
0024-3205
Subject:
acetylcholine; antagonists; arteries; ischemia; models; rats; stroke; vasodilation
Abstract:
... AIMS: Endothelin (ET) receptor A antagonism decreases neuronal damage in experimental models of stroke. Since large arteries like basilar artery contribute significantly to total cerebrovascular resistance and are major determinants of microvascular pressure, dysregulation of basilar artery function may worsen stroke injury. ET-1 is involved in the regulation of basilar constriction. However, whet ...
DOI:
10.1016/j.lfs.2012.01.020
PubMed:
22365958
PubMed Central:
PMC3744059

38. The effect of intravenous insulin infusion on renal blood flow in conscious sheep is partially mediated by nitric oxide but not by prostaglandins

Author:
I. Tebot; J.-M. Bonnet; C. Paquet; J.-Y. Ayoub; S. M. Da Silva; V. Louzier; A. Cirio
Source:
Journal of animal science 2012 v.90 no.4 pp. 1192-1200
ISSN:
0021-8812
Subject:
arteries; blood; blood flow; glucose; hypokalemia; insulin; intravenous injection; ketoprofen; nitric oxide; potassium chloride; prostaglandin synthase; prostaglandins; sheep; telemetry
Abstract:
... To test the effect of insulin on renal perfusion and the participation of NO and PG as mediators of this response, renal blood flow (RBF) was measured in sheep (n = 8) implanted with ultrasonic flow probes around renal arteries and with a systemic arterial pressure (SAP, n = 4) telemetry device. Three protocols were performed: 1) RBF and SAP were recorded (0800 to 1800 h) in fed and fasted sheep, ...
DOI:
10.2527/jas.2011-4129
PubMed:
22064745

39. A non-damaging chemical amination protocol for poly(ethylene terephthalate) – application to the design of functionalized compliant vascular grafts

Author:
Samantha Noel; Benoît Liberelle; Alvaro Yogi; Maria J. Moreno; Martin N. Bureau; Lucie Robitaille; Gregory De Crescenzo
Source:
Journal of materials chemistry B 2012 v.1 no.2 pp. 230-238
ISSN:
2050-7518
Subject:
amination; aminolysis; arteries; bioengineering; compliance; ethylenediamines; moieties; polyethylene terephthalates; tensile strength
Abstract:
... Bioengineering approaches have been intensively applied to create small diameter vascular grafts using artificial materials. However, a fully successful, high performing and anti-thrombogenic structure has not been achieved yet. In this study, we present the first step of a process aiming at biofunctionalizing previously designed compliant polyethylene terephthalate (PET) scaffolds (Moreno et al., ...
DOI:
10.1039/c2tb00082b

40. The relationship between urban combined traffic noise and annoyance: An investigation in Dalian, north of China

Author:
Guoqing Di; Xiaoyi Liu; Qili Lin; Yue Zheng; Lingjiao He
Source:
Science of the total environment 2012 v.432 no. pp. 189-194
ISSN:
0048-9697
Subject:
arteries; buildings; computer software; noise pollution; people; railroads; residential areas; roads; surveys; traffic; China
Abstract:
... Several residential areas in Dalian, north of China, were selected to investigate the influence of combined traffic noise pollution on urban residents. The software Cadna/A was used to estimate the day-night equivalent noise level (Ldₙ) at 1m from the windows of each building, which were modified according to the actual data. Annoyance has been identified as the most important psychological impact ...
DOI:
10.1016/j.scitotenv.2012.05.034
PubMed:
22728964

41. Amelogenesis Imperfecta and Other Biomineralization Defects in Fam20a and Fam20c Null Mice

Author:
P. Vogel; G. M. Hansen; R. W. Read; R. B. Vance; M. Thiel; J. Liu; T. J. Wronski; D. D. Smith; S. Jeter-Jones; R. Brommage
Source:
Veterinary pathology v.49 no.6 pp. 998-1017
ISSN:
1544-2217
Subject:
adulthood; alkaline phosphatase; animal pathology; arteries; biomineralization; blood serum; bones; calcification; death; gene expression; growth retardation; knockout mutants; loss-of-function mutation; mice; mortality; osteomalacia; protein secretion; proteins; rickets; teeth
Abstract:
... The FAM20 family of secreted proteins consists of three members (FAM20A, FAM20B, and FAM20C) recently linked to developmental disorders suggesting roles for FAM20 proteins in modulating biomineralization processes. The authors report here findings in knockout mice having null mutations affecting each of the three FAM20 proteins. Both Fam20a and Fam20c null mice survived to adulthood and showed bio ...
DOI:
10.1177/0300985812453177

42. Arterial shear stress augments the differentiation of endothelial progenitor cells adhered to VEGF-bound surfaces

Author:
Yoshinori Suzuki; Kimiko Yamamoto; Joji Ando; Kunio Matsumoto; Takehisa Matsuda
Source:
Biochemical and biophysical research communications 2012 v.423 no.1 pp. 91-97
ISSN:
0006-291X
Subject:
arteries; blood coagulation factors; cell growth; endothelial cells; humans; mechanotransduction; messenger RNA; mitogen-activated protein kinase; models; shear stress; stem cells; swine; vascular endothelial growth factors
Abstract:
... Our ongoing studies show that vascular endothelial cell growth factor (VEGF)-bound surfaces selectively capture endothelial progenitor cells (EPCs) in vitro and in vivo, and that surface-bound VEGF stimulates intracellular signal transduction pathways over prolonged culture periods, resulting in inductive differentiation of EPCs. In this article, we investigated whether simulated arterial shear st ...
DOI:
10.1016/j.bbrc.2012.05.088

43. Characterization of 5-hydroxytryptamine-induced contraction and acetylcholine-induced relaxation in isolated chicken basilar artery

Author:
F. Matsumoto; Y. Watanabe; T. Obi; M. Z. Islam; E. Yamazaki-Himeno; M. Shiraishi; A. Miyamoto
Source:
Poultry science 2012 v.91 no.5 pp. 1158-1164
ISSN:
0032-5791
Subject:
acetylcholine; antagonists; arteries; atropine; broiler chickens; cholinergic receptors; dose response; endothelial cells; nitric oxide; nitric oxide synthase; serotonin; vasoconstriction; vasodilation
Abstract:
... The aim of the present study was to clarify the responsiveness of the chicken basilar artery to 5-hydroxytryptamine (5-HT) and acetylcholine (ACh) and to characterize the related receptor subtypes in vitro. Basilar arteries were obtained from freshly slaughtered broiler chickens. The 5-HT induced concentration-dependent contraction of the arteries. The concentration-response curves for 5-HT were s ...
DOI:
10.3382/ps.2011-01945
PubMed:
22499874

44. Characterization of chicken endoglin, a member of the zona pellucida family of proteins, and its tissue expression

Author:
Elisa Rossi; Carmen Langa; Alvaro Gilsanz; Francisco J. Blanco; Juan Ayllón; Enrique Villar; Luisa M. Botella; Carlos Cabañas; Marlene Shaw; Carmelo Bernabeu
Source:
Gene 2012 v.491 no.1 pp. 31-39
ISSN:
0378-1119
Subject:
Western blotting; angiogenesis; arteries; bursa of Fabricius; chickens; complementary DNA; endothelial cells; endothelium; flow cytometry; fluorescence microscopy; fluorescent antibody technique; genes; humans; monoclonal antibodies; mucosa; mutation; precipitin tests; protein synthesis; proteins; skin lesions; transforming growth factor beta; zona pellucida
Abstract:
... Endoglin is a TGF-β co-receptor expressed in endothelial cells, where it plays a crucial role in angiogenesis, cardiovascular development and vascular remodeling. In humans, mutations in the endoglin gene give rise to Hereditary Hemorrhagic Telangiectasia type 1 (HHT1), an autosomal dominant disorder associated with vascular lesions in skin, mucosa and internal organs. So far, endoglin cDNA has be ...
DOI:
10.1016/j.gene.2011.09.010
PubMed:
21982971

45. Chronic social isolation in the prairie vole induces endothelial dysfunction: implications for depression and cardiovascular disease

Author:
Jacob D. Peuler; Melissa-Ann L. Scotti; Laura E. Phelps; Neal McNeal; Angela J. Grippo
Source:
Physiology & behavior 2012 v.106 no.4 pp. 476-484
ISSN:
0031-9384
Subject:
Microtus ochrogaster; acetylcholine; adrenergic agents; animal models; arteries; cardiovascular diseases; endothelium; humans; nitric oxide; nitroprusside; patients; phenylephrine; smooth muscle; vasodilation
Abstract:
... Humans with depression show impaired endothelium-dependent vasodilation; one recent demonstration of which was in the form of a reduced acetylcholine (ACh)-induced relaxation of adrenergically-precontracted small arteries biopsied from older depressed patients. Results from such uses of ACh in general have been validated as the most predictive marker of endothelium-related cardiovascular diseases. ...
DOI:
10.1016/j.physbeh.2012.03.019
PubMed:
22469565
PubMed Central:
PMC3355378

46. Colour and Pulsed Doppler Ultrasonographic Study of the Canine Testis

Author:
JD Carrillo; M Soler; X Lucas; A Agut
Source:
Reproduction in domestic animals 2012 v.47 no.4 pp. 655-659
ISSN:
0936-6768
Subject:
arteries; blood flow; dogs; testes; ultrasonography
Abstract:
... This study was performed to characterize the normal blood flow of the canine testis and to measure the peak systolic velocity (PSV), end‐diastolic velocity (EDV), resistive index (RI) and pulsatility index (PI) of testicular arteries weekly during a period of 6 months in five healthy Beagle dogs and to evaluate whether there were any change along this time. The ultrasonographic exams were made wit ...
DOI:
10.1111/j.1439-0531.2011.01937.x
PubMed:
22117645

47. Comparison of how well conscious cats tolerate blood pressure measurement from the radial and coccygeal arteries

Author:
Martha J Cannon; Jo Brett
Source:
Journal of feline medicine and surgery v.14 no.12 pp. 906-909
ISSN:
1532-2750
Subject:
arteries; cats; diastolic blood pressure; equipment; hypertension; systolic blood pressure; veterinary clinics
Abstract:
... Hypertension is a common condition of older cats and acquiring clinically relevant and repeatable blood pressure (BP) measurements in conscious cats is important in its diagnosis and management. The most common sites for indirect BP measurement in the cat are the radial artery (RA) and the coccygeal artery (CA) but, to date, there are no published data comparing how conscious cats tolerate BP meas ...
DOI:
10.1177/1098612X12455023

48. Decidual spiral artery remodeling during early post-implantation period in mice: Investigation of associations with decidual uNK cells and invasive trophoblast

Author:
Fotini Charalambous; Artemis Elia; Pantelis Georgiades
Source:
Biochemical and biophysical research communications 2012 v.417 no.2 pp. 847-852
ISSN:
0006-291X
Subject:
agglutinins; arteries; blood flow; humans; lymphocytes; mice; morphometry; pregnancy; trophoblast
Abstract:
... Circumferential remodeling of spiral arteries (SAs) during pregnancy is crucial for regulating maternal blood flow into the placenta and clinically important. However its mechanism is still ill defined in humans and mice. In mice, several important aspects of decidual SA remodeling (SAR) remain unexplored and were addressed here using morphometrics by examining SAs within the mesometrial half of t ...
DOI:
10.1016/j.bbrc.2011.12.057

49. ET-1 deletion from endothelial cells protects the kidney during the extension phase of ischemia/reperfusion injury

Author:
Nur Arfian; Noriaki Emoto; Nicolas Vignon-Zellweger; Kazuhiko Nakayama; Keiko Yagi; Ken-ichi Hirata
Source:
Biochemical and biophysical research communications 2012 v.425 no.2 pp. 443-449
ISSN:
0006-291X
Subject:
Western blotting; actin; arteries; blood serum; cell proliferation; creatinine; endothelial cells; endothelial nitric oxide synthase; inflammation; ischemia; kidneys; macrophages; mice; oxidative stress; patients; prognosis; proliferating cell nuclear antigen; protein kinase C; quantitative polymerase chain reaction; renal failure; renal function; smooth muscle
Abstract:
... BACKGROUND: The prognosis of patients after acute kidney injury (AKI) is poor and treatment is limited. AKI is mainly caused by renal ischemia/reperfusion injury (IRI). During the extension phase of IRI, endothelial damage may participate in ischemia and inflammation. Endothelin-1 (ET-1) which is mostly secreted by endothelial cells is an important actor of IRI, particularly through its strong vas ...
DOI:
10.1016/j.bbrc.2012.07.121

50. Effects of sedation with acepromazine maleate and buprenorphine hydrochloride on femoral artery blood flow in healthy dogs

Author:
R.B. Nogueira; M.J. Fernández del Palacio; J.T. López; R.M. Resende
Source:
Research in veterinary science 2012 v.93 no.2 pp. 989-992
ISSN:
0034-5288
Subject:
Beagle; acepromazine; adults; arteries; blood; blood flow; buprenorphine; diastolic blood pressure; dispersions; dogs; heart rate; maleates; sedation; ultrasonography
Abstract:
... The purpose of this study was to qualify and quantify the femoral artery blood flow by duplex Doppler ultrasonography (DDU) in healthy dogs, before and after the administration of a combination of acepromazine maleate and buprenorphine hydrochloride (ACP–BPN). Seven healthy adult mongrel dogs and three adult beagles were used. Heart rate, arterial blood pressure and measurement of femoral artery b ...
DOI:
10.1016/j.rvsc.2011.10.004
PubMed:
22047817

51. Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

Author:
Swapnil K. Sonkusare; Adrian D. Bonev; Jonathan Ledoux; Wolfgang Liedtke; Michael I. Kotlikoff; Thomas J. Heppner; David C. Hill-Eubanks; Mark T. Nelson
Source:
Science 2012 v.336 no.6081 pp. 597-601
ISSN:
0036-8075
Subject:
arteries; calcium; cations; endothelial cells; endothelium; potassium; smooth muscle; vasodilation
Abstract:
... Major features of the transcellular signaling mechanism responsible for endothelium-dependent regulation of vascular smooth muscle tone are unresolved. We identified local calcium (Ca2+) signals ("sparklets") in the vascular endothelium of resistance arteries that represent Ca2+ influx through single TRPV4 cation channels. Gating of individual TRPV4 channels within a four-channel cluster was coope ...
DOI:
10.1126/science.1216283
PubMed:
22556255
PubMed Central:
PMC3715993

52. Enzootic calcinosis caused by Nierembergia rivularis in sheep

Author:
Carmen García y Santos; Rodrigo Pereira; Gabriel Etcheberry; Juan M. Goyen; William Pérez; Alejandra Capelli; Eduardo Alonso; Alejandro Ruiz-Díaz; Franklin Riet-Correa
Source:
Journal of veterinary diagnostic investigation v.24 no.2 pp. 423-426
ISSN:
1943-4936
Subject:
Nierembergia; anorexia; arteries; cachexia; calcinosis; flocks; grazing; heart; kidneys; lungs; necropsy; pastures; sheep; weight loss; Uruguay
Abstract:
... Enzootic calcinosis was diagnosed in sheep in Uruguay in pastures containing the plant Nierembergia rivularis. In a flock of 200 sheep, 20 were affected and 12 died. Clinical signs were anorexia, weight loss followed by cachexia, stiffness, and kyphosis. At necropsy and histologic examination, mineral deposits were observed on the medial layer of the arteries, heart, lungs, and kidneys. Similar le ...
DOI:
10.1177/1040638711435143
PubMed:
22379059

53. Evaluation of a technique for measurement of flow-mediated vasodilation in healthy ponies

Author:
Finding, Elizabeth J.T.; Jones, Ian D.; Fuentes, Virginia Luis; Menzies-Gow, Nicola J.
Source:
American journal of veterinary research 2012 v.73 no.6 pp. 755-761
ISSN:
0002-9645
Subject:
arteries; blood pressure; body condition; cardiovascular diseases; correlation; deflation; dogs; humans; inflation; laminitis; mares; ultrasonography; vasodilation
Abstract:
... Objective: To determine between-pony and within-pony variations and interobserver and intraobserver agreements of a technique for measurement of flow-mediated vasodilation (FMD) in healthy ponies Animals: 6 healthy pony mares (weight range, 236 to 406 kg; body condition score range, 3/9 to 7/9; age range, 14 to 25 years). Procedures: In each pony, the left median artery was occluded with a blood p ...
DOI:
10.2460/ajvr.73.6.755

54. Hypoplastic aberrant left subclavian artery in a dog with a persistent right aortic arch

Author:
Bryan Bottorff; D. David Sisson
Source:
Journal of veterinary cardiology 2012 v.14 no.2 pp. 381-385
ISSN:
1760-2734
Subject:
arteries; cardiovascular diseases; case studies; computed tomography; dogs; veterinary medicine
Abstract:
... Vascular ring anomalies (VRA) are relatively uncommon cardiovascular disorders in canine patients. The most common VRA is a persistent right aortic arch (PRAA) with a left ligamentum arteriosum, however various other vascular anomalies resulting in tracheoesophageal compression have also been reported. We report a case of a dog with a PRAA and left ligamentum arteriosum with a hypoplastic aberrant ...
DOI:
10.1016/j.jvc.2012.01.013
PubMed:
22561608

55. Morphology and distribution of blood fluke eggs and associated pathology in the gills of cultured Pacific bluefin tuna, Thunnus orientalis

Author:
Sho Shirakashi; Yoshiki Kishimoto; Ryuhei Kinami; Hiromitsu Katano; Katsuya Ishimaru; Osamu Murata; Naoki Itoh; Kazuo Ogawa
Source:
Parasitology international 2012 v.61 no.2 pp. 242-249
ISSN:
1383-5769
Subject:
Cardicola; Opisthorchis; Thunnus orientalis; arteries; blood; blood flukes; correlation; eggs; encapsulation; fibroblasts; gills; histopathology; internal transcribed spacers; mortality; parasitology; risk; sodium hydroxide; tuna; Japan
Abstract:
... Infestations of blood flukes of the genus Cardicola have been observed in juvenile Pacific bluefin tuna (PBT) cultured in Japan. Infected fish harbor large numbers of parasite eggs in their gills. Although the link between blood fluke infection and juvenile mortality is not clear, accumulation of parasite eggs appears to be pathogenic to the fish. We investigated the origins, general morphology/di ...
DOI:
10.1016/j.parint.2011.10.002

56. Preliminary report of novel technique for cryopreservation—Vacuum-assisted cryoprotectant infiltration

Author:
Kazutaka Soejima; Katsumi Shimoda; Masaki Takeuchi; Takashi Yamaki; Taro Kono; Hiroyuki Sakurai; Hiroaki Nakazawa
Source:
Cryobiology 2012 v.65 no.1 pp. 21-26
ISSN:
0011-2240
Subject:
arteries; atmospheric pressure; cryopreservation; cryoprotectants; glycerol; ice; muscle tissues; muscles; necrosis; rats; thighs
Abstract:
... To date, cryopreservation of large soft tissues has not been successfully achieved because of limitation of cryoprotective agent (CPA) infiltration into the tissue. This study aimed to investigate the effects of a vacuum on the tissue-infiltration of a CPA. An instant pickle-maker was modified for use as a vacuum apparatus, and glycerol was selected as the CPA. Twenty-six rats were used, and their ...
DOI:
10.1016/j.cryobiol.2012.03.006

57. Protective effect of hydroalcoholic extract of Mimusops elengi Linn. flowers against middle cerebral artery occlusion induced brain injury in rats

Author:
P. Nagakannan; B.D. Shivasharan; B.S. Thippeswamy; V.P. Veerapur; Punit Bansal
Source:
Journal of ethnopharmacology 2012 v.140 no.2 pp. 247-254
ISSN:
0378-8741
Subject:
Mimusops elengi; antioxidant activity; antioxidants; anxiety; arteries; biomarkers; blood-brain barrier; brain; edema; flowers; high performance liquid chromatography; infarction; ischemia; medicine; neuroprotective effect; nitrites; oxidative stress; rats; stroke
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: In the traditional Indian and Thai system of medicine, Mimusops elengi Linn., flower is used as brain tonic and to calm anxiety and panic attacks. AIM OF THE STUDY: The present study was designed to investigate the neuroprotective effect of hydroalcoholic extract of Mimusops elengi (ME) against cerebral ischemic reperfusion injury in rats. MATERIALS AND METHODS: Mal ...
DOI:
10.1016/j.jep.2012.01.012
PubMed:
22281124

58. Right ventricular hypertrophy with heart failure in Holstein heifers at elevation of 1,600 meters

Author:
Christopher R. Malherbe; Jana Marquard; David E. Legg; Kristi M. Cammack; Donal O’Toole
Source:
Journal of veterinary diagnostic investigation v.24 no.5 pp. 867-877
ISSN:
1943-4936
Subject:
Holstein; altitude; arteries; ascites; atrophy; cardiomyopathy; dairies; death; dyspnea; heart failure; heifers; hypertension; hypertrophy; lungs; myocardium; necropsy; pneumonia; transportation; weight loss; yearlings; Colorado; Wisconsin
Abstract:
... A syndrome of progressive right-sided heart failure occurred among yearling Holsteins at a heifer-raising facility and 2 dairies on the Colorado Front Range between 2007 and 2011. Most cases were seen at the heifer-raising facility, where the disease ranked second only to pneumonia as a major cause of death in animals aged <1.5 years. The disease resulted in the death or premature sale of 55 anima ...
DOI:
10.1177/1040638712453580
PubMed:
22914818

59. Thermographic mapping of the skin surface of the head in bald-headed male subjects

Author:
Linn Eva Hauvik; James B. Mercer
Source:
Journal of thermal biology 2012 v.37 no.7 pp. 510-516
ISSN:
0306-4565
Subject:
arteries; blood; cold; cooling; equipment; eyes; face; humans; males; nose; thermography
Abstract:
... Thermal patterns on the skin are related to skin blood perfusion. While knowledge concerning thermal distribution patterns of the face are well established, the thermal distribution patterns of the skin surface of other aspects of the head has only been investigated once previously in a study employing low resolution thermographic equipment [van Dulken, H., van Voss, S.F.C.H, 1971. The normal ther ...
DOI:
10.1016/j.jtherbio.2012.05.004

60. Triplex Doppler evaluation of uterine arteries in cyclic and pregnant domestic cats

Author:
B.S. Pereira; L.M.P. Freire; J.N. Pinto; S.F.S. Domingues; L.D.M. Silva
Source:
Animal reproduction science 2012 v.130 no.1-2 pp. 99-104
ISSN:
0378-4320
Subject:
arteries; blood flow; cats; estrous cycle; fetus; pregnancy; uterus
Abstract:
... The aims were to determine resistance index (RI) and pulsatility index (PI) in the uterine arteries of cyclic and pregnant domestic cats comparing the left and right uterine horns, as well as the majority or minority uterine horns, based on fetus number per horn; to determine the presence or absence of an early diastolic notch (EDN) in the uterine artery of pregnant queens. Ten domestic cats were ...
DOI:
10.1016/j.anireprosci.2011.12.019

61. Tubular hydrogels of circumferentially aligned nanofibers to encapsulate and orient vascular cells

Author:
Mark T. McClendon; Samuel I. Stupp
Source:
Biomaterials 2012 v.33 no.23 pp. 5713-5722
ISSN:
0142-9612
Subject:
X-radiation; arteries; cell viability; crosslinking; encapsulation; gelation; gels; hydrocolloids; myocytes; nanofibers; smooth muscle
Abstract:
... There is a great clinical need for tissue engineered blood vessels that could be used to replace or bypass damaged arteries. The success of such grafts will depend strongly on their ability to mimic the cellular and matrix organization found in native arteries, but currently available cell scaffolds such as electrospun fibers or hydrogels lack the ability to simultaneously encapsulate and align ce ...
DOI:
10.1016/j.biomaterials.2012.04.040
PubMed:
22591610
PubMed Central:
PMC3388037

62. Type 1 Diabetes Increases the Expression of Proinflammatory Cytokines and Adhesion Molecules in the Artery Wall of Candidate Patients for Kidney Transplantation

Author:
Javier Triñanes; Eduardo Salido; Julián Fernández; Margarita Rufino; José Manuel González-Posada; Armando Torres; Domingo Hernández
Source:
Diabetes care 2012 v.35 no.2 pp. 427-433
ISSN:
0149-5992
Subject:
adhesion; arteries; cell adhesion; fibrosis; inflammation; insulin-dependent diabetes mellitus; interleukin-6; kidney diseases; kidney transplant; patients; proteins
Abstract:
... OBJECTIVE: Diabetes may accelerate atheromatosis in uremic patients. Our aim was to assess the influence of type 1 diabetes on the atheromatosis-related inflammation in patients with chronic kidney disease (CKD). RESEARCH DESIGN AND METHODS: We analyzed the expression of proinflammatory cytokines and adhesion molecules in the inferior epigastric artery walls of type 1 diabetic patients with CKD (n ...
DOI:
10.2337/dc11-1665
PubMed:
22210567
PubMed Central:
PMC3263898

63. Ultrasonographic measurement of flow-mediated vasodilation in dogs with chronic valvular disease

Author:
Ian D. Jones; Virginia Luis Fuentes; Adrian Boswood; Melanie J. Hezzell; David Wrigglesworth; Ana Mateus; Walasinee Moonarmart; Jonathan Elliott
Source:
Journal of veterinary cardiology 2012 v.14 no.1 pp. 203-210
ISSN:
1760-2734
Subject:
arteries; body weight; chronic diseases; dogs; foot-and-mouth disease; ultrasonography; vasodilation
Abstract:
... OBJECTIVES: To measure flow-mediated vasodilation (FMD) in healthy dogs and in client-owned dogs with chronic valvular disease (CVD) and to investigate possible correlations between markers of CVD severity and FMD. ANIMALS: Twelve dogs with CVD and 11 healthy weight-matched dogs. METHODS: Brachial artery FMD following 5 min inflation of a cuff around the antebrachium was measured in 12 dogs with C ...
DOI:
10.1016/j.jvc.2011.09.004
PubMed:
22366570

64. Uterine artery blood flow remains unchanged in pregnant mares in response to short-term administration of pentoxifylline

Author:
C.S. Bailey; R.B. Sper; J.L. Schewmaker; C.N. Buchanan; T.M. Beachler; M.A. Pozor; M.D. Whitacre
Source:
Theriogenology 2012 v.77 no.2 pp. 430-436
ISSN:
0093-691X
Subject:
arteries; blood flow; gestational age; mares; mouth; pentoxifylline; pregnancy; syrups; ultrasonics
Abstract:
... The objective of this study was to use Doppler ultrasound technology to determine whether pentoxifylline administration increased uterine blood flow in normal pregnant pony mares. Thirteen pregnant pony mares between 18 and 190 d of gestation (mean ± SEM, 101 ± 55) were utilized for the study during two trial periods. In each trial, pentoxifylline (17 mg/kg by mouth every 12h, diluted in syrup) wa ...
DOI:
10.1016/j.theriogenology.2011.08.018
PubMed:
21958635

65. Uterine vascular degeneration is present throughout the uterine wall of multiparous mares. Colinearity between elastosis, endometrial grade, age and parity

Author:
A. Esteller-Vico; I.K. Liu; S. Couto
Source:
Theriogenology 2012 v.78 no.5 pp. 1078-1084
ISSN:
0093-691X
Subject:
arteries; blood flow; elastin; foals; mares; necropsy
Abstract:
... Vascular degeneration is present in endometrial vessels of multiparous aged mares. The lesions associated with vascular degeneration consist of enlargement, duplication and splitting of the membrana elastica interna and perivascular deposits of elastin. However, there are no similar data available for deep myometrial vessels and the vascular layer. The objectives of the present study were to chara ...
DOI:
10.1016/j.theriogenology.2012.04.014
PubMed:
22763073

66. Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation

Author:
Ágnes Czikora; Erzsébet Lizanecz; Judit Boczán; Andrea Daragó; Zoltán Papp; István Édes; Attila Tóth
Source:
Life sciences 2012 v.90 no.11-12 pp. 407-415
ISSN:
0024-3205
Subject:
agonists; metabolism; endothelium; cannabinoids; immunohistochemistry; smooth muscle; autoregulation; capsaicin; linoleate 13S-lipoxygenase; indomethacin; arachidonic acid; myocytes; cytochrome P-450; skeletal muscle; blood cells; vasodilation; prostaglandin synthase; rats; arteries
Abstract:
... AIMS: We hypothesized that arachidonic acid produced by anandamide breakdown contributes to the vascular effects of anandamide. MAIN METHODS: Isolated, pressurized rat skeletal muscle arteries, which possess spontaneous myogenic tone, were treated with anandamide, arachidonic acid, capsaicin (vanilloid receptor agonist), WIN 55-212-2 (cannabinoid receptor agonist), URB-597 (FAAH inhibitor), baical ...
DOI:
10.1016/j.lfs.2011.12.016

67. The impairment of metrial gland development in tamoxifen exposed rats

Author:
Satoshi Furukawa; Seigo Hayashi; Koji Usuda; Masayoshi Abe; Izumi Ogawa
Source:
Experimental and toxicologic pathology 2012 v.64 no.1-2 pp. 121-126
ISSN:
0940-2993
Subject:
arteries; body weight; endometrium; fetal death; fetus; histopathology; placenta; pregnancy; rats; stromal cells; tamoxifen
Abstract:
... We examined the sequential histopathological changes in the placenta from rats exposed to tamoxifen. Tamoxifen was administered intraperitoneally at doses of 0 and 2mg/kg/day on gestation days (GDs) 8, 9 and 10, and the placentas were sampled on GDs 11, 13, 15, 17, and 21. The fetal mortality rates in the tamoxifen group were increased up to 56%. However, there were no effects on the weights of li ...
DOI:
10.1016/j.etp.2010.07.004

68. A model of cerebral ischemia induction in neonatal rabbits

Author:
Sedigheh Ebrahimi; Soheil Ashkani Esfahani; Mahboobeh Kohkiloezadeh; Behnam Hamzeh Moghaddam; Shahrbanu Askarian; Nader Tanideh; Amin Tamadon
Source:
Journal of applied animal research 2012 v.40 no.1 pp. 37-42
ISSN:
0974-1844
Subject:
animal models; arteries; brain damage; decapitation; hippocampus; humans; hypoxia; ischemia; necrosis; neonates; neurons; rabbits
Abstract:
... Perinatal cerebral ischemia is a major cause of brain damage in the human newborn. Animal models of the brain ischemia provided important roles for extension of the pathophysiological knowledge and evaluating of the efficacy of therapeutic interventions. The purpose of the present study was to introduce a cerebral ischemia model of rabbit neonates which provides useful clues for assessing the isch ...
DOI:
10.1080/09712119.2011.627134

69. The next Great Trek? South African commercial farmers move north

Author:
Ruth Hall
Source:
Journal of peasant studies 2012 v.39 no.3-4 pp. 823-843
ISSN:
1743-9361
Subject:
agribusiness; arteries; business enterprises; capital; farmers; funding; sugars; Mozambique; South Africa; Zambia
Abstract:
... This paper analyses the shifting role of South African farmers, agribusiness and capital elsewhere in the Southern African region and the rest of the continent. It explores recent trends in this expansion, and investigates the interests and agendas shaping such deals, and the ideologies and discourses of legitimation employed in favour of them. While for the past two decades small numbers of South ...
DOI:
10.1080/03066150.2012.677037

70. βPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin αᵥβ₈

Author:
Jing Liu; Lei Zeng; Regan M. Kennedy; Nicole M. Gruenig; Sarah J. Childs
Source:
Developmental biology 2012 v.363 no.1 pp. 95-105
ISSN:
0012-1606
Subject:
angiogenesis; arteries; brain; cell proliferation; embryogenesis; endothelial cells; hemorrhage; integrins; mutants; mutation; phenotype; regulatory proteins; scaffolding proteins
Abstract:
... The growth of new blood vessels by angiogenesis and their stabilization by the recruitment of perivascular mural cells are thought to be two sequential, yet independent events. Here we identify molecular links between both processes through the βPix and integrin αᵥβ₈ proteins. Bubblehead (bbh) mutants with a genetic mutation in βPix show defective vascular stabilization. βPix is a guanine nucleoti ...
DOI:
10.1016/j.ydbio.2011.12.022