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You searched for: Publication Year 2012 Remove constraint Publication Year: 2012 Subject term arteries Remove constraint Subject term: arteries
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1. 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside Inhibits Proliferation of Vascular Smooth Muscle Cells: Involvement of NO/cGMP/PKG Pathway

Author:
Xiao‐Le Xu; Yan‐Juan Huang; Xiang‐Fan Chen; Dan‐Yan Lin; Wei Zhang
Source:
Phytotherapy research 2012 v.26 no.7 pp. 1068-1074
ISSN:
0951-418X
Subject:
cGMP-dependent protein kinase; atherosclerosis; growth factors; nitric oxide; smooth muscle; DNA; cyclic GMP; guanylate cyclase; flow cytometry; myocytes; cell proliferation; arteries; cell cycle; Reynoutria multiflora
Abstract:
... The proliferation of vascular smooth muscle cells (VSMCs) induced by injury to the intima of arteries is an important etiologic factor in vascular proliferative disorders such as atherosclerosis and restenosis. 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside (TSG), an active component extracted from Polygonum multiflorum, has been found to have an antiatherosclerotic effect. The aim of this study ...
DOI:
10.1002/ptr.3691
PubMed:
22213189

2. Acute, quercetin-induced reductions in blood pressure in hypertensive individuals are not secondary to lower plasma angiotensin-converting enzyme activity or endothelin-1: nitric oxide

Author:
Abigail Larson; Melissa A.H. Witman; Yi Guo; Stephen Ives; Russell S. Richardson; Richard S. Bruno; Thunder Jalili; J. David Symons
Source:
Nutrition research 2012 v.32 no.8 pp. 557-564
ISSN:
0271-5317
Subject:
arteries; bioavailability; blood pressure; enzyme activity; men; nitric oxide; nitrites; peptidyl-dipeptidase A; placebos; quercetin
Abstract:
... Quercetin (Q) reduces blood pressure (BP) in hypertensive individuals, but the mechanism is unknown. We hypothesized that acute Q aglycone administration reduces BP in hypertensive men by decreasing angiotensin-converting enzyme (ACE) activity and/or by lowering the ratio of circulating endothelin-1 (ET-1) to nitric oxide and that these alterations will improve endothelial function. Using a double ...
DOI:
10.1016/j.nutres.2012.06.018
PubMed:
22935338

3. Agreement between direct, oscillometric and Doppler ultrasound blood pressures using three different cuff positions in anesthetized dogs

Author:
Natache A Garofalo; Francisco J Teixeira Neto; Renata K Alvaides; Flávia A de Oliveira; Wangles Pignaton; Renato T Pinheiro
Source:
Veterinary anaesthesia and analgesia 2012 v.39 no.4 pp. 324-334
ISSN:
1467-2987
Subject:
adults; arteries; carpus; catheters; dogs; dopamine; hypertension; hypotension; isoflurane; monitoring; prospective studies; systolic blood pressure; ultrasonics
Abstract:
... Objective To evaluate the agreement between invasive blood pressure (IBP) and Doppler ultrasound blood pressure (DUBP) using three cuff positions and oscillometric blood pressure (OBP) in anesthetized dogs. Study design Prospective study. Animals Nine adult dogs weighing 14.5–29.5 kg. Methods The cuff was placed above and below the tarsus, and above the carpus with the DUBP and above the carpus wi ...
DOI:
10.1111/j.1467-2995.2012.00711.x
PubMed:
22414262

4. Altered adipocyte progenitor population and adipose-related gene profile in adipose tissue by long-term high-fat diet in mice

Author:
Xiaohua Xu; Cuiqing Liu; Zhaobin Xu; Kevin Tzan; Aixia Wang; Sanjay Rajagopalan; Qinghua Sun
Source:
Life sciences 2012 v.90 no.25-26 pp. 1001-1009
ISSN:
0024-3205
Subject:
adipocytes; adiponectin; arteries; gene expression; genes; glucose; glucose tolerance tests; high fat diet; hyperplasia; hypertrophy; inflammation; insulin resistance; long term effects; metabolism; mice; obesity; stem cells; white adipose tissue
Abstract:
... AIMS: High-fat diet (HFD) is associated with adipose inflammation, which contributes to key components of metabolic abnormalities. The expanded adipose tissue mass associated with obesity is the result of hyperplasia and hypertrophy of adipocytes. In this study, we investigated the effects of long-term HFD on adipocyte progenitor cell (APC) population and adipose-specific gene profiles in both whi ...
DOI:
10.1016/j.lfs.2012.05.016
PubMed:
22683431
PubMed Central:
PMC3390972

5. Anatomical Relationship Between the Collecting System and the Intrarenal Arteries in the Rabbit: Contribution for an Experimental Model

Author:
A. Shalgum; B. P. S. Marques‐Sampaio; A. Dafalla; M. A. Pereira‐Sampaio
Source:
Anatomia, histologia, embryologia 2012 v.41 no.2 pp. 130-138
ISSN:
0340-2096
Subject:
arteries; humans; kidneys; models; rabbits
Abstract:
... With 6 figures and 2 tables SUMMARY: Intrarenal anatomy was studied in detail to evaluate how useful rabbits could be as a urologic model. Only one renal artery was observed, which was divided into dorsal and ventral branches in all cases. Three segmental arteries (cranial, mesorenal and caudal) was the most frequent branching pattern found in both the dorsal and ventral division. There was an imp ...
DOI:
10.1111/j.1439-0264.2011.01112.x
PubMed:
22017266

6. Arteriolar vascular smooth muscle cells: Mechanotransducers in a complex environment

Author:
Michael A. Hill; Gerald A. Meininger
Source:
international journal of biochemistry & cell biology 2012 v.44 no.9 pp. 1505-1510
ISSN:
1357-2725
Subject:
arteries; blood flow; calcium; cell membranes; cytoskeleton; deformation; extracellular matrix; integrins; ion channels; mechanotransduction; myocytes; receptors; smooth muscle
Abstract:
... Contraction of small artery (diameters typically less than 250μm) vascular smooth muscle cells (VSMCs) plays a critical role in local control of blood flow and arterial pressure through its affect on vascular caliber. Specifically, contraction of small arteries in response to increased intraluminal pressure is referred to as the myogenic response and represents an important role for mechanotransdu ...
DOI:
10.1016/j.biocel.2012.05.021
PubMed:
22677491
PubMed Central:
PMC4221252

7. Blood Flow Characteristics of the Human Lactating Breast

Author:
Donna T. Geddes; Khalidah M. Aljazaf; Jacqueline C. Kent; Danielle K. Prime; Diane L. Spatz; Catherine P. Garbin; Ching Tat Lai; Peter E. Hartmann
Source:
Journal of human lactation 2012 v.28 no.2 pp. 145-152
ISSN:
0890-3344
Subject:
arteries; blood flow; breast milk; breasts; lactating women; lactation; milk production; milk synthesis; ultrasonics
Abstract:
... BACKGROUND: Despite the increased metabolic activity of the lactating breast, no studies have been carried out to determine mammary blood flow (MBF) parameters or the relationship between MBF and milk production in women. The aim of this study was to measure the MBF in the internal mammary artery (IMA) and lateral thoracic artery (LTA) of lactating women and determine if these were related to milk ...
DOI:
10.1177/0890334411435414
PubMed:
22526342

8. Catalysis-Based Inhibitors of the Calcium Signaling Function of CD38

Author:
Kwong Anna KaYee; Chen Zhe; Zhang HongMin; Leung Fung Ping; Lam Connie Mo Ching; Ting Kai Yiu; Zhang Liangren; Hao Quan; Zhang Li-He; Lee Hon Cheung
Source:
Biochemistry 2012 v.51 no.1 pp. 555-564
ISSN:
1520-4995
Subject:
X-ray diffraction; adenosine diphosphate; arteries; calcium; calcium signaling; esterases; genes; humans; mesentery; mice; oxytocin; rats; retinoic acid; ribose; social behavior; structure-activity relationships
Abstract:
... CD38 is a signaling enzyme responsible for catalyzing the synthesis of cyclic ADP ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate; both are universal Ca²⁺ messenger molecules. Ablation of the CD38 gene in mice causes multiple physiological defects, including impaired oxytocin release, that result in altered social behavior. A series of catalysis-based inhibitors of CD38 were desig ...
DOI:
10.1021/bi201509f

9. Comparison of direct and Doppler arterial blood pressure measurements in rabbits during isoflurane anaesthesia

Author:
Louise Harvey; Toby Knowles; Pamela J Murison
Source:
Veterinary anaesthesia and analgesia 2012 v.39 no.2 pp. 174-184
ISSN:
1467-2987
Subject:
anesthesia; arteries; blood pressure; carpus; castration; catheters; forelimbs; hypotension; isoflurane; monitoring; prospective studies; rabbits
Abstract:
... Objective To measure the level of agreement between Doppler measured (DOP) arterial blood pressure (ABP) in the forelimb and directly measured (DIR) auricular systolic ABP (SAP) and mean ABP (MAP) in isoflurane‐anaesthetized rabbits. Study design Prospective clinical study. Animals Data were analysed from 17 of 24 healthy rabbits, weighing 1.3–2.8 kg. Methods Rabbits were anaesthetized for neuteri ...
DOI:
10.1111/j.1467-2995.2011.00685.x
PubMed:
22356416

10. Compressive Myelopathy Associated With Ectasia of the Vertebral and Spinal Arteries in a Dog

Author:
C. C. Bozynski; L. Vasquez; D. P. O’Brien; G. C. Johnson
Source:
Veterinary pathology v.49 no.5 pp. 779-783
ISSN:
1544-2217
Subject:
animal pathology; arteries; cervical spine; dogs; fibrosis; hemorrhage; magnetic resonance imaging; necropsy; nerve tissue; spinal cord; thrombosis
Abstract:
... A 4-year-old dog was presented for acute, progressive tetraparesis and cervical hyperesthesia. Symmetrical tubular structures coursing along the lateroventral aspects of the spinal cord at the fourth and fifth cervical vertebrae were identified in magnetic resonance images. At necropsy, vertebral arteries and their spinal branches were severely ectatic bilaterally, and the cervical spinal cord was ...
DOI:
10.1177/0300985811415704

11. Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling

Author:
Linda Chang; Michela Noseda; Michelle Higginson; Michelle Ly; Alexandre Patenaude; Megan Fuller; Alastair H. Kyle; Andrew I. Minchinton; Mira C. Puri; Daniel J. Dumont; Aly Karsan
Source:
Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.18 pp. 6993-6998
ISSN:
0027-8424
Subject:
adults; arteries; embryogenesis; hemorrhage; mice; myocytes; smooth muscle; stem cells
Abstract:
... Vascular smooth muscle cells (VSMC) have been suggested to arise from various developmental sources during embryogenesis, depending on the vascular bed. However, evidence also points to a common subpopulation of vascular progenitor cells predisposed to VSMC fate in the embryo. In the present study, we use binary transgenic reporter mice to identify a Tie1+CD31dimvascular endothelial (VE)-cadherin– ...
DOI:
10.1073/pnas.1118512109
PubMed:
22509029
PubMed Central:
PMC3345008

12. Doppler sonography of the uterine and ovarian arteries during a superovulatory program in horses

Author:
M.C. Witt; H. Bollwein; J. Probst; C. Baackmann; E.L. Squires; H. Sieme
Source:
Theriogenology 2012 v.77 no.7 pp. 1406-1414
ISSN:
0093-691X
Subject:
animal ovaries; arteries; blood flow; correlation; estrogens; follicular development; human chorionic gonadotropin; insemination; mares; ovulation; progesterone; steroid hormones; superovulation
Abstract:
... The aim of the present study was to investigate the effects of a gonadotropin treatment to induce superovulation on ovarian and uterine blood flow and its relationship with steroid hormone levels and ovarian response in mares, using color Doppler sonography. Each of six mares were examined sonographically in five cycles for 3 d (t1 to t3) during the follicular development phase (FDP) beginning at ...
DOI:
10.1016/j.theriogenology.2011.11.005
PubMed:
22196623

13. Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats

Author:
Ismaila A. Raji; Pierre Mugabo; Kenechukwu Obikeze
Source:
Journal of ethnopharmacology 2012 v.140 no.1 pp. 98-106
ISSN:
0378-8741
Subject:
Tulbaghia; acetates; adrenergic receptors; angiotensin I; angiotensin II; arteries; blood pressure; enzymes; heart rate; humans; intravenous injection; leaf extracts; males; methanol; phenylephrine; rats; salts
Abstract:
... ETHNOPHARMACOLOGICAL RELEVANCE: Tulbaghia violacea Harv. (Alliaceae) is a small bulbous herb which belongs to the family Alliaceae, most commonly associated with onions and garlic. In South Africa, this herb has been traditionally used in the treatment of various ailments, including fever, colds, asthma, paralysis, hypertension and stomach problems. The aim of this study was to evaluate the effect ...
DOI:
10.1016/j.jep.2011.12.034
PubMed:
22222281

14. Effects of FSH and LH on ovarian and follicular blood flow, follicular growth and oocyte developmental competence in young and old mares

Author:
J.L. Altermatt; A.J. Marolf; R.H. Wrigley; E.M. Carnevale
Source:
Animal reproduction science 2012 v.133 no.3-4 pp. 191-197
ISSN:
0378-4320
Subject:
animal ovaries; arteries; blastocyst; blood flow; color; elderly; follicle-stimulating hormone; luteinizing hormone; mares; oocytes; pregnancy; spermatozoa; ultrasonography
Abstract:
... Objectives of the experiment were to determine the effects of mare age and gonadotropin treatments on dominant follicle vascularity, ovarian blood flow and dominant follicle growth and to associate follicular vascularity with oocyte developmental capacity. Growing follicles >30mm from young (4–9 years) and old (>20 years) mares were assessed for blood flow using color Doppler ultrasonography befor ...
DOI:
10.1016/j.anireprosci.2012.06.021

15. Endothelin-1 and -2: Two amino acids matter

Author:
Matthijs G. Compeer; Dennis P.L. Suylen; Tilman M. Hackeng; Jo G.R. De Mey
Source:
Life sciences 2012 v.91 no.13-14 pp. 607-612
ISSN:
0024-3205
Subject:
agonists; amino acids; antagonists; arteries; chimerism; endothelium; nerve tissue; rats; receptors; smooth muscle
Abstract:
... AIMS: Endothelin-1 (ET-1) and endothelin-2 (ET-2; Trp⁶Leu⁷ET-1) are expressed by different cell types, but are considered to display identical pharmacological properties on endothelin receptors. We studied agonist-dependent aspects of endothelinA (ETA)-receptor function and the importance of amino acids 6 and 7 of ET-1 and ET-2 in this respect. MAIN METHODS: We used isolated rat mesenteric resista ...
DOI:
10.1016/j.lfs.2012.02.011

16. Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict

Author:
Robert M. Samstein; Steven Z. Josefowicz; Aaron Arvey; Piper M. Treuting; Alexander Y. Rudensky
Source:
Cell 2012 v.150 no.1 pp. 29-38
ISSN:
0092-8674
Subject:
T-lymphocytes; arteries; autoimmunity; evolution; females; fetal resorption; males; mammals; placenta; pregnancy; thymus gland; transcription factors
Abstract:
... Regulatory T (Treg) cells, whose differentiation and function are controlled by X chromosome-encoded transcription factor Foxp3, are generated in the thymus (tTreg) and extrathymically (peripheral, pTreg), and their deficiency results in fatal autoimmunity. Here, we demonstrate that a Foxp3 enhancer, conserved noncoding sequence 1 (CNS1), essential for pTreg but dispensable for tTreg cell generati ...
DOI:
10.1016/j.cell.2012.05.031
PubMed:
22770213
PubMed Central:
PMC3422629

17. Histological evidence: housekeeping genes beta-actin and GAPDH are of limited value for normalization of gene expression

Author:
Juntang Lin; Christoph Redies
Source:
Development genes and evolution 2012 v.222 no.6 pp. 369-376
ISSN:
0949-944X
Subject:
Northern blotting; Western blotting; actin; arteries; cardiomyocytes; chickens; digestive tract; embryogenesis; essential genes; gene expression; gizzard; in situ hybridization; liver; messenger RNA; reverse transcriptase polymerase chain reaction
Abstract:
... Housekeeping genes are widely used as internal controls for gene expression normalization for western blotting, northern blotting, RT-PCR, etc. They are generally thought to be expressed in all cells of the organism at similar levels because it is assumed that these genes are required for the maintenance of basic cellular function as constitutive genes. However, real-time RT-PCR experiments reveal ...
DOI:
10.1007/s00427-012-0420-x
PubMed:
23099774

18. Histological examination of vascular lesions caused by stent implantation in humans and in comparative experimental animal model

Author:
G. Kasza; L. Kollár; Erzsébet Rőth; A. Vincze; Éva Gömöri
Source:
Acta biologica Hungarica 2012 v.63 no.1 pp. 1-14
ISSN:
0236-5383
Subject:
animal models; arteries; cell proliferation; dogs; humans; immunohistochemistry; tissues
Abstract:
... A comparative analysis of human and experimental animal (canine) tissues was performed to characterize and describe cellular and histological responses during the processes of newly forming intravascular tissues after stent implantation. Routine histological and immunohistochemical evaluation of 20 human samples and 9 samples from animal models were used one day, one week and one month after the s ...
DOI:
10.1556/ABiol.63.2012.1.1

19. Human cytomegalovirus infection inhibits CXCL12- mediated migration and invasion of human extravillous cytotrophoblasts

Author:
Jessica A Warner; Kevin J Zwezdaryk; Bonita Day; Deborah E Sullivan; Gabriella Pridjian; Cindy A Morris
Source:
Virology journal 2012 v.9 no.1 pp. 255
ISSN:
1743-422X
Subject:
CXCR4 receptor; abortion (animals); animal viruses; arteries; atypical chemokine receptor 3; cell lines; chemokine CXCL12; congenital abnormalities; epidermal growth factor; hepatocyte growth factor; humans; invasive species; messenger RNA; mitogens; pre-eclampsia; pregnancy; secretion; signal transduction; trophoblast; viruses
Abstract:
... BACKGROUND: During the first trimester of pregnancy, a series of tightly regulated interactions govern the formation of a highly invasive population of fetal-derived extravillous cytotrophoblasts (EVT). Successful pregnancy is dependent on efficient invasion of the uterine wall and maternal spiral arteries by EVT. Dysregulated trophoblast invasion is associated with intrauterine growth restriction ...
DOI:
10.1186/1743-422X-9-255

20. Identification of orexins and cognate receptors in the lacrimal gland of sheep

Author:
Cecilia Dall’Aglio; Francesca Mercati; Margherita Maranesi; Cristiano Boiti
Source:
Peptides 2012 v.35 no.1 pp. 36-41
ISSN:
0196-9781
Subject:
arteries; cytoplasm; gene expression; genes; immunohistochemistry; lacrimal apparatus; receptors; reverse transcriptase polymerase chain reaction; sheep
Abstract:
... The aim of the present work was to study, by means of immunohistochemical and RT-PCR techniques, the presence and distribution of immunopositivity for orexin A and B (OXA and OXB) and orexin type 1 and 2 receptors (OX₁R and OX₂R) in the lacrimal gland of sheep as well as the gene expressions for prepro-orexin (PPOX) and cognate receptors. In serial sections, positive staining for OXA and OXB were ...
DOI:
10.1016/j.peptides.2012.03.012