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You searched for: Publication Year 2007 Remove constraint Publication Year: 2007 Subject DNA-directed RNA polymerase Remove constraint Subject: DNA-directed RNA polymerase Subject messenger RNA Remove constraint Subject: messenger RNA Subject term Escherichia coli Remove constraint Subject term: Escherichia coli
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1. Effects of Friedreich's ataxia (GAA)n·(TTC)n repeats on RNA synthesis and stability

Author:
Krasilnikova, Maria M.; Kireeva, Maria L.; Petrovic, Vladimir; Knijnikova, Nelli; Kashlev, Mikhail; Mirkin, Sergei M.
Source:
Nucleic acids research 2007 v.35 no.4 pp. 1075-1084
ISSN:
0305-1048
Subject:
messenger RNA; models; plasmids; dissociation; gene expression; transcription (genetics); neurodegenerative diseases; ataxia (disorder); DNA-directed RNA polymerase; introns; Escherichia coli
Abstract:
... Expansions of (GAA)n repeats within the first intron of the frataxin gene reduce its expression, resulting in a hereditary neurodegenerative disorder, Friedreich's ataxia. While it is generally believed that expanded (GAA)n repeats block transcription elongation, fine mechanisms responsible for gene repression are not fully understood. To follow the effects of (GAA)n·(TTC)n repeats on gene express ...
DOI:
10.1093/nar/gkl1140
PubMed:
17264130
PubMed Central:
PMC1851639

2. The role of the omega subunit of RNA polymerase in expression of the relA gene in Escherichia coli

Author:
Chatterji, Dipankar; Ogawa, Yoshito; Shimada, Tomohiro; Ishihama, Akira
Source:
FEMS microbiology letters 2007 v.267 no.1 pp. 51-55
ISSN:
0378-1097
Subject:
messenger RNA; starvation; stress response; DNA microarrays; gene expression; ribosomal proteins; operon; DNA-directed RNA polymerase; Escherichia coli
Abstract:
... The rpoZ gene for the omega subunit of Escherichia coli RNA polymerase constitutes single operon with the spoT gene, which is responsible for the maintenance of stringent response under nutrient starvation conditions. To identify the physiological role of the omega subunit, we compared the gene expression profile of wild-type Escherichia coli with that of an rpoZ deleted strain by microarray analy ...
DOI:
10.1111/j.1574-6968.2006.00532.x