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... An anticoagulant was purified from a Chinese herb, Taraxacum platycarpum. Its activity was heat-labile, and was decreased by incubation with subtilisin Carlburg or proteinase K, indicating that the active component was a protein. The protein had a molecular mass of 31 kDa by gel filtration and 33 kDa by sodium dodecyl sulfate polyacrylamide gel electrophoresis, so it probably was a monomer. When p ...
... Background: The short-chain fatty acids formed in the human colon by the bacterial fermentation of fiber may have an antiinflammatory effect, may reduce insulin production, and may improve lipid metabolism. We previously showed in hypercholesterolemic patients that supplementation with the probiotic bacteria Lactobacillus plantarum 299v significantly lowers concentrations of LDL cholesterol and fi ...
... Background: Alcohol may impair protein turnover and insulin sensitivity in vivo. Objective: The acute effects of moderate wine intake on amino acid kinetics and on the fractional synthetic rate (FSR) of albumin and fibrinogen in patients with type 1 diabetes were studied. Design: Six patients with type 1 diabetes ingested an elementary mixed meal (46 kJ/kg) over 4 h, first without and 3 mo later w ...
... Objective-To evaluate hematologic and serum biochemical changes in Salmonella ser Typhimurium infected calves. Animals-16 male 3- to 4-week-old dairy calves. Procedure-13 calves were experimentally infected with S Typhimurium (strains IR715 and CS401, which are derivatives of ATCC 14028), and 3 calves were uninfected controls. Several hematologic and serum biochemical parameters were measured. Res ...
... Fluorometric cell attachment assays together with competitive inhibitors of adhesion were used to probe for the presence of integrins, a diverse family of heterodimeric cell-surface glycoproteins involved in cell-cell and cell-extracellular matrix adhesion, in the fibroblastic rainbow trout cell line, RTG-2. The adhesive properties of this cell line were evaluated. RTG-2 cells adhered poorly to TC ...
... Fibrinogen-binding proteins were found in the culture supernatants of Mannheimia haemolytica serotype 1 (ATCC 43270) and Pasteurella trehalosi serotype 10 (ECO-100). Sheep fibrinogen was biotinylated and shown to bind to proteins in the culture supernatants by modified western blot. Fibrinogen-binding proteins in the culture supernatant may be important virulence factors leading to the characteris ...
... Objective: To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen. Design: Randomized, diet-controlled, cross-over study. Setting: The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands. Subjects: Ten middle-aged men and 10 postmenopausal women, all apparently healthy, non-smoking and moderate alcohol drinker ...
apolipoprotein A-I; blood; blood lipids; fasting; fibrinogen; high density lipoprotein cholesterol; isoflavones; low density lipoprotein cholesterol; men; myocardial ischemia; plant estrogens; plasminogen activator; risk factors; soy protein; soybeans; transforming growth factor beta 1; women
Abstract:
... Background: Soybeans contain estrogenic isoflavones that may influence plasma concentrations of transforming growth factor β1 (TGF-β1) and plasma lipid and hemostatic risk factors for coronary heart disease. Objective: We compared the effects of moderate intakes of soy protein containing intact phytoestrogens (high-isoflavone diet) and soy protein from which most of the phytoestrogens had been ext ...
C-reactive protein; children; edema; fibrinogen; glycoproteins; protein energy malnutrition; stress response
Abstract:
... Background: Immune structure and function are more compromised in edematous protein-energy malnutrition (PEM) than in nonedematous PEM. Whether the positive acute-phase protein (APP) response to infection is affected remains unknown. Objective: We assessed whether children with edematous PEM can mount a general APP response and compared the kinetic mechanisms of the response in children with edema ...
... An experimental venous clot model using the lateral saphenous vein of sheep is described. Eight experimental Suffolk crossbred sheep were used. A mixture of human fibrinogen, in some cases labelled with (125)I, bovine thrombin and homologous whole blood was placed via a catheter into a surgically isolated segment of the lateral saphenous vein. The resulting heterologous clot was imaged daily for 6 ...
... The possible interference of haemolysis, lipaemia, bilirubinaemia and fibrinogen on capillary zone electrophoresis of canine samples were studied. Solutions of haemoglobin, lipid and bilirubin were prepared and mixed with serum aliquots to make up samples containing different concentrations of the putative interferent substance. In addition, samples of serum and plasma were assayed to assess the i ...
antigens; body mass index; coagulation; factor VII; females; fibrinogen; fibrinolysis; high density lipoprotein cholesterol; ingestion; insulin; males; nutrition research; nutritional intervention; overweight; pain; patients; plasminogen activator inhibitors; public health; risk; t-plasminogen activator; triacylglycerols; viscosity; volunteers; weight loss
Abstract:
... Objective: To evaluate the effects of moderate weight loss, in overweight patients with angina, on plasma coagulation, fibrinolytic indicies and pain frequency. Design: Single-stranded 12-week dietary intervention, an individualised eating plan with quantitative advice delivered by a dietitian. Target weight loss of 0.5 kg per week. Setting: Outpatient research clinic. Subjects: Fifty-four volunte ...
fibrinogen; gels; response surface methodology; water holding capacity
Abstract:
... Response surface methodology (RSM) was applied to optimize the water-holding capacity (WHC) of fibrinogen/plasma protein gels heated at 75°C for 10 min to develop a new edible gel. The effects of varying the amount of fibrinogen, plasma protein, calcium, and pH were evaluated to optimize the WHC using RSM. Estimation of the overall effects of the 4 factors on the gels revealed that the pH and conc ...
... Objective-To correlate serum concentrations of fibrinogen (Fib), haptoglobin (Hap), serum amyloid-A (SAA), and alpha-1 acid glycoprotein (AGP) with clinical respiratory tract disease and response to treatment in transport-stressed feedlot cattle fed vitamin E-supplemented diets. Animals-387 heifer calves (mean initial weight, 197 kg). Procedure-Calves purchased from an order buyer were delivered t ...
... Objective: To examine the relation between fitness and fibrinogen, white blood cell count, uric acid and metabolic syndrome across levels of adiposity in apparently healthy, nonsmoking men. Design: Cross-sectional study of 4057 men from the Aerobics Center Longitudinal Study examining the age-adjusted resting levels and risk of having a clinically significant elevation of fibrinogen, white blood c ...
... Objective-To evaluate efficacy and safety of IP administration of high-molecular-weight carboxymethylcellulose (HMW CMC) for the prevention of postoperative intra-abdominal adhesions in ponies. Animals-10 ponies. Procedure-A 1% solution of HMW CMC was instilled intra-abdominally prior to surgery in 5 ponies, whereas 5 control ponies did not receive HMW CMC. Postoperative adhesions were induced by ...