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1. Acetylation of PCNA Sliding Surface by Eco1 Promotes Genome Stability through Homologous Recombination

Author:
Pierre Billon; Jian Li; Jean-Philippe Lambert; Yizhang Chen; Véronique Tremblay; Joseph S. Brunzelle; Anne-Claude Gingras; Alain Verreault; Tomohiko Sugiyama; Jean-Francois Couture; Jacques Côté
Source:
Molecular cell 2017 v.65 no.1 pp. 78-90
ISSN:
1097-2765
Subject:
DNA; DNA damage; DNA replication; acetylation; cohesion; crystal structure; genome; homologous recombination; lysine; mutation; post-translational modification; proliferating cell nuclear antigen; protein subunits
Abstract:
... During DNA replication, proliferating cell nuclear antigen (PCNA) adopts a ring-shaped structure to promote processive DNA synthesis, acting as a sliding clamp for polymerases. Known posttranslational modifications function at the outer surface of the PCNA ring to favor DNA damage bypass. Here, we demonstrate that acetylation of lysine residues at the inner surface of PCNA is induced by DNA lesion ...
DOI:
10.1016/j.molcel.2016.10.033

2. Acute photosensitisation and mortality in a herd of dairy cattle in Tasmania

Author:
HM Golder; N Moss; G Rogers; B Jackson; N Gannon; PTW Wong; IJ Lean
Source:
New Zealand veterinary journal 2017 v.65 no.1 pp. 39-45
ISSN:
1176-0710
Subject:
Holstein; Hordeum murinum; Jamesdicksonia; Jersey; abomasum; arid lands; aspartate transaminase; barley; blood sampling; cows; dairy cattle; distress; eczema; edema; erythema; fumonisins; gall bladder; gamma-glutamyltransferase; gastritis; glutamate dehydrogenase; grasses; grazing; herds; histopathology; ingestion; lactation; liver; liver diseases; metabolites; milk yield; morbidity; mortality; mycotoxicosis; necropsy; pain; pastures; photosensitivity; smut diseases; vocalization; zearalenone; Tasmania
Abstract:
... CASE HISTORY: A herd of Holstein, Jersey, or Holstein-Jersey cross lactating cattle of mixed ages presented with a sudden drop in milk yield in 94/678 cows on 3 October 2014 (Day 0). The herd was located in Gretna in the Derwent Valley (Tasmania, Australia) and had been grazing dryland pasture. CLINICAL FINDINGS: On Day 0 the cows variably showed recumbency, peracute photosensitisation, inflamed c ...
DOI:
10.1080/00480169.2016.1232181

3. Advances in culture and genetic modification approaches to lipid biosynthesis for biofuel production and in silico analysis of enzymatic dominions in proteins related to lipid biosynthesis in algae

Author:
Yahaira J. Tamayo‐Ordóñez; Benjamin A. Ayil‐Gutiérrez; Felipe L. Sánchez‐Teyer; Erika A. De la Cruz‐Arguijo; Francisco A. Tamayo‐Ordóñez; Atl Victor Córdova‐Quiroz; Maria C. Tamayo‐Ordóñez
Source:
Phycological research 2017 v.65 no.1 pp. 14-28
ISSN:
1322-0829
Subject:
acetyl-CoA carboxylase; acyl coenzyme A; algae culture; amino acid sequences; biofuels; bioinformatics; biosynthesis; diacylglycerol acyltransferase; fatty acid composition; fossil fuels; fuel production; genes; genetic engineering; glycerol-3-phosphate acyltransferase; lipids; microalgae; protein tertiary structure; proteins
Abstract:
... Biofuels have been shown to be a promising and highly attractive alternative for minimizing the use of fossil fuels, and microalgae have positioned themselves as potential candidates for production of lipids and other substances of commercial interest. We briefly review recent advances made in microalgae culture conditions and genetic manipulation for improving lipid yields for biofuel production ...
DOI:
10.1111/pre.12162

4. Alteration of fatty acid chain length of Chlamydomonas reinhardtii by simultaneous expression of medium‐chain‐specific thioesterase and acyl carrier protein

Author:
Yu Inaba; Kenji Nakahigashi; Takuro Ito; Masaru Tomita
Source:
Phycological research 2017 v.65 no.1 pp. 94-99
ISSN:
1322-0829
Subject:
Chlamydomonas reinhardtii; Cuphea lanceolata; acyl carrier protein; algae; biofuels; cost effectiveness; free fatty acids; genes; genetic engineering; liquid chromatography; mass spectrometry; medium chain fatty acids; triacylglycerols
Abstract:
... Biofuel from fatty acids with chain lengths of 8–15 (C8–C15) have properties similar to those of conventional diesel and jet fuels, thus, can save time and reduce costs for the refurbishment of engines and maintenance of oiling facilities. Most oil‐producing algae yield C16–C18 fatty acids; however, the manipulation of algae using genetic engineering is a promising approach to obtain C8–C15 fatty ...
DOI:
10.1111/pre.12161

5. Antimicrobial activity of the acidophilic eukaryotic microalga Coccomyxa onubensis

Author:
Francisco Navarro; Eduardo Forján; María Vázquez; Alberto Toimil; Zaida Montero; María del C. Ruiz‐Domínguez; Inés Garbayo; Miguel Á. Castaño; Carlos Vílchez; José M. Vega
Source:
Phycological research 2017 v.65 no.1 pp. 38-43
ISSN:
1322-0829
Subject:
Staphylococcus aureus; fatty acids; Coccomyxa; chloroform; ethyl ether; Gram-positive bacteria; Salmonella enterica; risk; Proteus mirabilis; methylene chloride; carotenoids; hexane; Escherichia coli; antimicrobial properties; Candida albicans; minimum inhibitory concentration; yeasts; biomass; solvents; microalgae
Abstract:
... Extremophilic microalgae are unexplored as a source of pharmaceuticals despite the fact that its biomass can be produced at large scale with low risk of contamination. A significant amount of antimicrobial activity was produced by extracts obtained from the eukaryotic acidophilic microalgae Coccomyxa onubensis in non‐polar solvents, such as hexane, diethyl ether, and chloroform or in weakly polar ...
DOI:
10.1111/pre.12158

6. Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets

Author:
Lin Hsien-Chun; Lin Mei-Hsiang; Liao Jiahn-Haur; Wu Tzu-Hua; Lee Tzong-Huei; Mi Fwu-Long; Wu Chi-Hao; Chen Ku-Chung; Cheng Chia-Hsiung; Lin Cheng-Wei
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 51-59
ISSN:
1520-5118
Subject:
Taiwanofungus camphoratus; bioactive compounds; bioactive properties; colorectal neoplasms; gene expression regulation; genes; molecular models; mushrooms; neoplasm cells; phosphatidylinositol 3-kinase; ubiquinones
Abstract:
... Antroquinonol (ANQ) is a ubiquinone derivative from the unique mushroom Antrodia camphorata, which exhibits broad-spectrum bioactivities. The effects of ANQ on cancer stem cell-like properties in colon cancer, however, remain unclear. In this study, we found that ANQ inhibited growth of colon cancer cells. The 50% growth inhibitions (GI₅₀) of ANQ on HCT15 and LoVo were 34.8 ± 0.07 and 17.9 ± 0.07 ...
DOI:
10.1021/acs.jafc.6b04101

7. Applicability of fetal thoracic aortic diameter measurement in the prediction of birth weight in Holstein-Friesian cows — Short communication

Author:
Boglárka Vincze; András Gáspárdy; Levente Kovács; Ervin Albert; Luca Kézér; Ferenc Baska; Ottó Szenci
Source:
Acta veterinaria Hungarica 2017 v.65 no.1 pp. 60-65
ISSN:
1588-2705
Subject:
Holstein; aorta; birth weight; calves; calving; cows; fetus; heart rate; heifers; horses; prediction; ultrasonography
Abstract:
... Transabdominal ultrasonography has been shown to be a useful and reliable method for assessing fetal well-being in horses and cattle. To test the applicability of fetal aortic diameter measurement in cattle, 44 late-term pregnant cows and heifers were examined 21 to 0 days prior to calving. Mean fetal aortic diameter was 2.07 ± 0.14 cm and mean fetal heart rate (FHR) was 109 ± 17 bpm. Three dead c ...
DOI:
10.1556/004.2017.006

8. Arginine Methylation: The Coming of Age

Author:
Roméo S. Blanc; Stéphane Richard
Source:
Molecular cell 2017 v.65 no.1 pp. 8-24
ISSN:
1097-2765
Subject:
DNA damage; animal models; arginine; epigenetics; mammals; messenger RNA; methylation; methyltransferases; muscular diseases; neoplasms; post-translational modification; transcription factors; transgenic animals; translation (genetics)
Abstract:
... Arginine methylation is a common post-translational modification functioning as an epigenetic regulator of transcription and playing key roles in pre-mRNA splicing, DNA damage signaling, mRNA translation, cell signaling, and cell fate decision. Recently, a wealth of studies using transgenic mouse models and selective PRMT inhibitors helped define physiological roles for protein arginine methyltran ...
DOI:
10.1016/j.molcel.2016.11.003

9. Assessing the Effect of Organoclays and Biochar on the Fate of Abscisic Acid in Soil

Author:
Gámiz Beatriz; Cox Lucía; Hermosín M. Carmen; Spokas Kurt; Celis Rafael
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 29-38
ISSN:
1520-5118
Subject:
Limonia acidissima; abscisic acid; acid soils; agricultural soils; biochar; desorption; edaphic factors; enantiomers; leaching; rhizosphere; soil amendments
Abstract:
... The potential use of allelopathic and signaling compounds as environmentally friendly agrochemicals is a subject of increasing interest, but the fate of these compounds once they reach the soil environment is poorly understood. This work studied how the sorption, persistence, and leaching of the two enantiomers of the phytohormone abscisic acid (ABA) in agricultural soil was affected by the amendm ...
DOI:
10.1021/acs.jafc.6b03668

10. Bacteriophages as indicators of faecal pollution and enteric virus removal

Author:
B.R. McMinn; N.J. Ashbolt; A. Korajkic
Source:
Letters in applied microbiology 2017 v.65 no.1 pp. 11-26
ISSN:
0266-8254
Subject:
Bacteroides; Enterococcus; aquatic environment; coliphages; environmental factors; excreta; indicator species; infrastructure; pathogen survival; pathogens; pollution; surface water; wastewater; wastewater treatment
Abstract:
... Bacteriophages are an attractive alternative to faecal indicator bacteria (FIB), particularly as surrogates of enteric virus fate and transport, due to their closer morphological and biological properties. Based on a review of published data, we summarize densities of coliphages (F+ and somatic), Bacteroides spp. and enterococci bacteriophages (phages) in individual human waste, raw wastewater, am ...
DOI:
10.1111/lam.12736

11. Biosynthesis of Antroquinonol and 4-Acetylantroquinonol B via a Polyketide Pathway Using Orsellinic Acid as a Ring Precursor in Antrodia cinnamomea

Author:
Chou Kevin Chi-Chung; Yang Shang-Han; Wu Hsiang-Lin; Lin Pei-Yin; Chang Tsu-Liang; Sheu Fuu; Chen Kai-Hsien; Chiang Been-Huang
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 74-86
ISSN:
1520-5118
Subject:
Taiwanofungus camphoratus; acetyl coenzyme A; benzoquinones; biosynthesis; culture media; fungi; malonyl coenzyme A; mycelium; oleic acid; ubiquinones
Abstract:
... Antroquinonol (AQ) and 4-acetylantroquinonol B (4-AAQB), isolated from the mycelium of Antrodia cinnamomea, have a similar chemical backbone to coenzyme Q (CoQ). Based on the postulation that biosynthesis of both AQ and 4-AAQB in A. cinnamomea starts from the polyketide pathway, we cultivated this fungus in a culture medium containing [U-¹³C]oleic acid, and then we analyzed the crude extracts of t ...
DOI:
10.1021/acs.jafc.6b04346

12. Blueberry Anthocyanin-Enriched Extracts Attenuate Fine Particulate Matter (PM2.5)-Induced Cardiovascular Dysfunction

Author:
Wang Ziyu; Pang Wei; He Congcong; Li Yibo; Jiang Yugang; Guo Changjiang
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 87-94
ISSN:
1520-5118
Subject:
angiotensin II; apoptosis; biomarkers; blueberries; electrocardiography; endothelins; heart; heart rate; histopathology; inflammation; interleukin-10; interleukin-6; malondialdehyde; oxidative stress; particulates; protein synthesis; rats; superoxide dismutase
Abstract:
... Blueberry anthocyanin-enriched extracts (BAE) at three doses (0.5, 1.0, and 2.0 g/kg) were administered by oral gavage to rats exposed to 10 mg/kg fine particulate matter (PM₂.₅) three times a week. A positive control group was exposed to PM₂.₅ without BAE treatment. We analyzed heart rate (HR), electrocardiogram (ECG), and histopathology, and biomarkers of cardiovascular system injuries, systemic ...
DOI:
10.1021/acs.jafc.6b04603

13. Can Naturalness Indicator Values Reveal Habitat Degradation? A Test of Four Methodological Approaches

Author:
László Erdős; Zoltán Bátori; Károly Penksza; Andrea Dénes; Balázs Kevey; Dóra Kevey; Martin Magnes; Philipp Sengl; Csaba Tölgyesi
Source:
Polish Journal of Ecology 2017 v.65 no.1 pp. 1-13
ISSN:
1505-2249
Subject:
habitat destruction; habitats; vegetation; wildlife management
Abstract:
... Assessing habitat naturalness belongs to the most current issues in conservation biology. It has been recognized that plants are able to indicate the naturalness of their habitat. Thus, species may be given relative naturalness indicator values (i.e. scores on an ordinal scale), reflecting their different tolerances against habitat degradation. In the present study, our first goal was to test whet ...
DOI:
10.3161/15052249PJE2017.65.1.001

14. Characterisation of the nucleic acid binding features of the PRRSV 7ap and its ability to induce antinuclear antibodies

Author:
Ferenc Olasz; Béla Dénes; Ádám Bálint; Tibor Magyar; Sándor Belák; Zoltán Zádori
Source:
Acta veterinaria Hungarica 2017 v.65 no.1 pp. 124-134
ISSN:
1588-2705
Subject:
Porcine reproductive and respiratory syndrome virus; antibodies; gel electrophoresis; genes; mice; nucleic acids; nucleocapsid; open reading frames; proteins; swine
Abstract:
... A short alternative open reading frame named ORF7a has recently been discovered within the nucleocapsid gene of the porcine reproductive and respiratory syndrome virus (PRRSV) genome. Proteins (7ap) translated from the ORF7a of two divergent strains — a type I and a type II — are able to completely reduce the motility of nucleic acids at relatively high molar charge ratios in gel retardation assay ...
DOI:
10.1556/004.2017.013

15. Characterization of Wisconsin Giant Ragweed (Ambrosia trifida) Resistant to Cloransulam

Author:
Stacey M. Marion; Vince M. Davis; David E. Stoltenberg
Source:
Weed science 2017 v.65 no.1 pp. 41-51
ISSN:
0043-1745
Subject:
Ambrosia trifida; Glycine max; Zea mays; acetolactate synthase; amino acids; bioassays; cloransulam; corn; dose response; fecundity; genes; greenhouse production; leaf area; phenotype; plant height; planting; seeds; sequence analysis; soybeans; viability; weed science; Wisconsin
Abstract:
... A giant ragweed population with putative resistance to cloransulam was identified in a long-term corn—soybean rotation located in southern Wisconsin. The population represented the first potential instance of giant ragweed resistance to acetolactate synthase (ALS) inhibitors in the state. Seeds were collected from several plants and pooled for subsequent experiments. Whole-plant dose—response expe ...
DOI:
10.1614/WS-D-16-00083.1

16. Characterization of the Key Aroma Compounds in Heat-Processed Licorice (Succus Liquiritiae) by Means of Molecular Sensory Science

Author:
Wagner Juliane; Schieberle Peter; Granvogl Michael
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 132-138
ISSN:
1520-5118
Subject:
cineole; flavor compounds; isotope dilution technique; licorice; models; odor compounds; odors; stable isotopes; sucrose; vanillin
Abstract:
... Application of the sensomics concept elucidated the key odorants of heat-processed licorice (Succus Liquiritiae). Forty-nine aroma-active compounds with flavor dilution (FD) factors between 16 and 2048 were detected; 47 thereof were identified, 23 for the first time in heated licorice. 4-Hydroxy-2,5-dimethylfuran-3(2H)-one revealed the highest FD factor of 2048, followed by 3-hydroxy-4,5-dimethylf ...
DOI:
10.1021/acs.jafc.6b04499

17. Characterization of the Typical Potent Odorants in Chinese Roasted Sesame-like Flavor Type Liquor by Headspace Solid Phase Microextraction–Aroma Extract Dilution Analysis, with Special Emphasis on Sulfur-Containing Odorants

Author:
Sha Sha; Chen Shuang; Qian Michael; Wang Chengcheng; Xu Yan
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 123-131
ISSN:
1520-5118
Subject:
flavor; headspace analysis; mixing; models; odor compounds; odors; quantitative analysis
Abstract:
... The aroma profile of Chinese roasted sesame-like flavor type liquor was investigated by means of headspace solid phase microextraction–aroma extract dilution analysis (HS-SPME-AEDA). Sixty-three odor-active regions were detected by HS-SPME-AEDA with flavor dilution (FD) factors >5, and 58 of these were further identified. Among them, ethyl hexanoate, 2-furfurylthiol, dimethyl trisulfide, 3-methylb ...
DOI:
10.1021/acs.jafc.6b04242

18. Chemopreventive Potential of Powdered Red Wine Pomace Seasonings against Colorectal Cancer in HT-29 Cells

Author:
Del Pino-García Raquel; Rivero-Pérez María D.; González-SanJosé María L.; Ortega-Heras Miriam; García Lomillo Javier; Muñiz Pilar
Source:
Journal of agricultural and food chemistry 2017 v.65 no.1 pp. 66-73
ISSN:
1520-5118
Subject:
DNA damage; bioavailability; cell viability; chemoprevention; colon; colorectal neoplasms; dietary fiber; digestion; flavorings; inhibitory concentration 50; intestinal microorganisms; phenolic acids; polyphenols; pomace; red wines; seeds; short chain fatty acids; small intestine
Abstract:
... This study evaluates the antiproliferative and antigenotoxic actions of powdered red wine pomace seasonings (Sk-S, seedless; W–S, whole; Sd-S, seeds). In vitro gastrointestinal digested and colonic fermented fractions of the seasonings were used as cell treatments. Phenolic acids from Sk-S showed the highest bioaccessibility in the small intestine, whereas polyphenols contained in Sd-S might be th ...
DOI:
10.1021/acs.jafc.6b04561

19. Climate sensitivity of radial growth in Norway spruce (Picea abies (L.) Karst.) under different CO2 concentrations

Author:
Aysan Badraghi; Radek Pokorný; Kateřina Novosadová; Justina Pietras; Michal V. Marek
Source:
Metsanduslikud uurimused 2017 v.65 no.1 pp. 43-56
ISSN:
1736-8723
Subject:
Picea abies; air temperature; carbon dioxide; climatic factors; earlywood; growing season; latewood; trees
Abstract:
... This investigation examined the effects of two different carbon dioxide concentrations ([CO₂]): Ambient (A, 385 μmol (CO₂) mol⁻¹) and elevated (E, A+385 μmol (CO₂) mol⁻¹)) on the tree-ring width and early to latewood proportion in Norway spruce for seven years (2006-2012). Further, to improve our understanding of the influence of climatic variables, we assessed the effects of precipitation and tem ...
DOI:
10.1515/fsmu-2016-0011

20. Comparative anatomy of the assimilatory organs of Nepenthes species

Author:
Olusegun O. Osunkoya; Nurul Amal Muntassir
Source:
Australian journal of botany 2017 v.65 no.1 pp. 67-79
ISSN:
0067-1924
Subject:
correlation; longevity; Nepenthes ampullaria; gas exchange; nitrogen; nutrients; physicochemical properties; potassium; carnivores; stomata; mesophyll; lignin; phosphorus
Abstract:
... There is a lack of data on comparative anatomy of the assimilatory organs of the enigmatic carnivorous Nepenthes species; the linkages between their leaf tissue anatomy and physico-chemical properties are also rarely considered. We examined the anatomy of the leaf (lamina) and its conjoint pitcher in five Nepenthes species (Nepenthes ampullaria, N. bicalcarata, N. gracilis, N. hemsleyana and N. ra ...
DOI:
10.1071/BT16157