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... Diabetic nephropathy is one of the various complications of diabetes mellitus, affecting patients for lifetime. Earlier studies have revealed that genipin can not only improve diabetes, but also induce cytotoxicity. Therefore, it is not clear which effect of genipin on kidneys occurs, when it is used in the treatment of diabetes. In the present study, we performed nuclear magnetic resonance (NMR)- ...
Fabio de Oliveira Roque; Marcio Uehara-Prado; Francisco Valente-Neto; Jose Manuel Ochoa Quintero; Katia Torres Ribeiro; Marlucia Bonifacio Martins; Marcelo Gonçalves de Lima; Franco L. Souza; Erich Fischer; Urbano Lopes da Silva; Françoise Yoko Ishida; Andrew Gray-Spence; João Onofre Pereira Pinto; Danilo Bandini Ribeiro; Clarissa de Araujo Martins; Pierre Cyril Renaud; Olivier Pays; William E. Magnusson
... The necessity to create national to global-scale biodiversity monitoring systems as part of assessing progress toward biodiversity agendas presents a challenge for signatory countries. This is a brief review of ongoing Brazilian national initiatives that would allow the construction of a general biomonitoring network scheme in protected areas; with additional focus on linking independent monitorin ...
Buxus; Cydalima perspectalis; Drosophila suzukii; Halyomorpha halys; crops; introduced species; moths; pests; Caucasus region; South East Asia
Abstract:
... Drosophila suzukii (Matsumura, 1931) (Diptera: Drosophilidae), an agricultural pest originating from Southeast Asia, has been recorded for the first time in the Caucasus and may threaten crops within the region. In 2016, two introduced species, the Brown Marmorated Stink Bug – Halyomorpha halys Stal (Hemiptera: Pentatomidae) and the Buxus moth – Cydalima perspectalis (Walker) (Lepidoptera: Crambid ...
Oncorhynchus mykiss; fish; fish farms; fisheries; parasitoses; pathogens; species diversity; Armenia
Abstract:
... The aim of this work was to study and define the example of one pond fisheries of the Republic of glugеosis distribution of fish; the species composition of fish, affected by the causative agent of the disease; the intensity and extensity of invasion, and pathways of the pathogen into the territory of our Republic. Based on the results of the conducted research we can conclude that in pond farms o ...
... Air pollution is a major health issue, notably due to the presence of potentially toxic particulate matter with a diameter of lower than or equal to 2.5 µm, named ‘PM2.5.’ There is, however, few precise knowledge on the sources, fate and toxicity of particulate matter, notably because there is a lack of method to trace particulate matter in the long term and over large distances. Therefore, we pre ...
... In order to overcome the common local treatment failure of canine sinonasal tumours, integrated boost techniques were tried in the cobalt/orthovoltage era, but dismissed because of unacceptable early (acute) toxicity. Intriguingly, a recent calculation study of a simultaneously integrated boost (SIB) technique for sinonasal irradiation using intensity‐modulated radiation therapy (IMRT) predicted t ...
biodiversity; birds of prey; fuels; issues and policy; lead; mining; risk reduction; toxicity; water birds; wildlife; Argentina; Bolivia; Brazil; Chile; Colombia; Ecuador; Peru; Venezuela
Abstract:
... Lead contamination is a worldwide problem that affects the health of several bird species and can cause biodiversity loss. However, in South America there is little information about this problem and the species affected. The aim of this study is to compile existing knowledge about lead contamination in South American bird species and propose actions to mitigate this problem. Through a literature ...
E. Abma; W. De Spiegelaere; K. Vanderperren; E. Stock; L. Van Brantegem; I. Cornelis; S. Daminet; Y. Ni; M. Vynck; G. Verstraete; P. Smets; H. de Rooster
... Combretastatin A4‐phosphate (CA4P) is an anti‐tumour vascular targeting agent which selectively blocks tumour blood flow. Research on CA4P in rodent tumour models is extensive; however, knowledge of its effect on spontaneous cancer is scarce. This study was conducted in canine patients with spontaneous solid tumours. The goal was to assess the toxicity and efficacy of CA4P in various spontaneous t ...
... Mast cell tumours (MCTs) are commonly treated with radiation therapy, most often in a microscopic disease setting. Poorer outcomes are expected in patients with gross disease, and irradiation of gross disease may be associated with greater toxicity. The aim of this study was to compare acute radiation adverse events (AE) in dogs with gross and microscopic MCTs receiving radiotherapy. Fifty‐seven d ...
... Aquarium market is one of the main causes of exotic species dispersion, as it promotes the introduction of potential invaders on natural environments. In this scenario, e-commerce provides easy access of invasive plants from around the world. Despite the economic importance of this trade, few studies have addressed the patterns and extension of environmental problems associated with this market. U ...
4-hydroxybenzoic acid; Oriental traditional medicine; acetonitrile; amygdalin; benzoic acid; bioactive compounds; blood circulation; blood stasis; chemical structure; cholic acid; cinnamic acid; ethyl gallate; formic acid; ionization; methyl gallate; quality control; tandem mass spectrometry; ultra-performance liquid chromatography
Abstract:
... Guizhi Fuling capsule (GFC), a traditional Chinese medicine (TCM) with effects of promoting blood circulation and dissipating blood stasis, has been widely used in the clinic. Because of the complex matrix and various chemical structure types, quality control of GFC remains great challenge. In the present study, an ultra performance liquid chromatography hybrid triple-quadrupole mass spectrometry ...
... Bisenols and its derivatives are attractive heterocyclic compounds exhibiting a wide range of biological properties, including anticancer, antipyretic and antimicrobial characteristics. Many catalytic systems have been reported to enhance the synthesis of bisenols, but these catalytic systems suffer from several drawbacks, such as the use of external metals, expensive and toxic chemicals. Thus, th ...
... Integrative taxonomy seeks to approach the complex topic of species diagnosis using independent, complementary lines of evidence. Despite their ubiquity throughout North and Central America, taxonomy of the American leopard frogs (Anura: Ranidae: Rana: subgenus Pantherana) remains largely unresolved, and this is arguably nowhere truer than in the Central American country of Honduras, where there a ...
... Passion fruit (Passiflora edulis [Sims]) is currently ranked third among fruit exports from Kenya and has great potential since demand for both fresh fruit and processed juice is on a continuous increase. Although assessment of genetic variability of germplasm is indispensable for improvement and development of superior cultivars, little information is available on the genetic diversity of passion ...
... Evaluating agricultural loss due to flooding is essential for defining an appropriate risk level in flood management projects. This research introduces a method for computing annual damage risk for rice fields with respect to both spatial and temporal pattern of floods, while considering the effect of crop growth stages on the total damage. For finding the spatial pattern of floods, HEC-RAS was em ...
... The use of the well‐known powerful antioxidant ascorbate has recently become more widespread in human medicine. Intravenous administration of high‐dose ascorbate has been demonstrated to exert anticancer effects. It has resulted in effective cell death in vitro and inhibition of tumour growth in vivo. The aim of the current study was to evaluate the effects of high‐dose ascorbate on canine melanom ...
Western blotting; bladder; carcinogenesis; cell cycle checkpoints; cell growth; cell lines; dogs; dose response; enzyme inhibitors; epidermal growth factor; flow cytometry; humans; in vivo studies; interphase; intraperitoneal injection; mice; neoplasm cells; neoplasms; phosphorylation; prognosis; protein synthesis; sequence analysis; tissues
Abstract:
... Transitional cell carcinoma (TCC) accounts for >90% of canine malignant tumours occurring in urinary bladder, and the prognosis is poor. Our previous study, using RNA sequencing, showed that human epidermal growth factor 2 (HER2) was the most activated upstream regulator related to carcinogenesis in canine TCC. The aim of this study was to examine the anti‐tumour effect of lapatinib, a tyrosine ki ...
cities; climate change; climatic factors; decision making; drought; meteorological data; multivariate analysis; principal component analysis; risk assessment; variance; South Korea
Abstract:
... This study aimed to analyze the future vulnerability to agricultural drought of the Korean administrative units of cities (Si) and counties (Gun) following the climate change phenomenon. To assess the vulnerability in a quantitative manner and also to deal with different physical and socioeconomic data on the occurrence of agricultural drought, principal component analysis (PCA), a multivariate st ...
agricultural productivity; autocorrelation; decision making; electrical conductivity; environmental models; farmers; food safety; geostatistics; kriging; land productivity; laterites; normal distribution; organic carbon; phosphorus; potassium; prediction; soil pH; soil water; India
Abstract:
... Degradation of soil due to unsuitable land management practices is a chief impairment of optimum land productivity. The spatial variability of soil properties is needed for agricultural productivity, food safety and environmental modeling. The present study was conducted in lateritic soils of West Bengal, India to understand the spatial variability of soil properties using a geostatistical model. ...
crops; employment; employment opportunities; environmental impact; exports; gas emissions; income; industrial byproducts; pollution; raw materials; recycling; solid wastes; sugar beet; sugar content; sugar industry; sugarcane; sugars; wastewater; world markets
Abstract:
... Sugar is one of the oldest commodities in the world. It can be produced from sugarcane, sugar beet or other crops having sugar content. Wide applications of sugar make massive demand in the domestic including international market. An assessment of environmental impact for sugar processing industry has done in terms of production, processing, recycling, and utilization. Sugarcane mill has a signifi ...
... The present research was conducted to determine the reactions of 200 pure lines selected from bread wheat landraces collected from 18 provinces and seven regions of Turkey against bunt disease (Tilletia foetida) under field conditions for 3 years. Bunt disease reactions of pure lines were assessed based on the infected spike/total spike ratio. For visually assessed materials, the GGE-biplot method ...
... Contrary to the single pier, due to the complexity of the scour mechanism around pile groups, empirical methods do not give a satisfactory prediction for the scour depth around pier with multiple piles. It was shown recently that artificial neural networks (NNs) have better prediction performance than empirical methods. In order to exploit the full potential of the NN procedure for predicting the ...
... The last century was marked by a high demographic revolution and the fast development of urban environments. Now, more than 50% of the world’s 7.5 billion humans live in cities. This change has often induced the degradation of environmental quality in urban areas. As a consequence, management policies are now fostering the ‘return of nature’ in cities, which, in turn, is requiring a better underst ...
... Biologists, chemists, and physicists are collaborating to develop highly sensitive and specific biosensors for pathogen detection in the food, healthcare, and environmental sectors. Those novel biosensors allow quick detection and are thus expected to solve the issues of the emergence of highly virulent or antibiotic-resistant pathogens. This article reviews different types of biosensors used for ...
DDT (pesticide); Spirulina; cleaning; electron microscopy; models; organelles; phytoremediation; ultrastructure; water pollution; water treatment
Abstract:
... The presented work concerns studying a possibility of using blue-green alga (cyanobacteria) Spirulina for cleaning water polluted with DDT (1,1'-(2,2,2-trichloroethane-1,1-diyl)bis (4-chlorobenzene)). For this aim, at first the influence of different concentrations of DDT (1, 10 and 50 ppm) on the ability of growing of Spirulina and the intensity of uptake of DDT by blue-green alga have been inves ...
biodiversity conservation; ecosystem services; ecosystems; indigenous species; issues and policy; landscapes; ponds; wetland conservation; Brazil
Abstract:
... Pond systems perform a myriad of ecosystem services and make unique contributions to aquatic biodiversity conservation at the landscape scale. Despite their high conservation value, in Brazil, natural ponds have been lost and degraded at alarming rates. The remaining have become exceptionally vulnerable after the enactment of the recent Native Vegetation Protection Law (NVPL), whose unsustainable ...
Brevibacillus laterosporus; Chrysomelidae; biopesticides; larvicides; pest control; Armenia
Abstract:
... The paper discusses the main features of Brevibacillus laterosporus bacilli as bioinsecticides for pest control, as well as perspective sources for searching the novel cancerolytic substances of microbial origin. It has been established that the culture of B. laterosporus is widespread in Armenia as a highly active producer of protein inclusions against leaf beetles. Isolated strains of B. lateros ...
B-lymphocytes; T-cell lymphoma; cyclophosphamide; dogs; doxorubicin; drug therapy; prednisolone; vincristine
Abstract:
... Canine T cell lymphoma has previously been found to be a poor prognostic indicator compared with its B cell counterpart. The cyclophosphamide, doxorubicin, vincristine, and prednisolone protocol is widely accepted as a first line treatment for canine lymphoma. There have been several studies investigating alternative protocols for T cell lymphoma. This study investigated the use of a modified lomu ...
... Georgian oak (Quercus iberica Stev.) is basically prevailed in moderately warm and dry climate zones of Eastern Georgia. Georgian oak naturally grows at elevations of 500–1000 m above sea level, it can reach 1400 m on the southern exposure slopes. Oak forests in Georgia are presented in the form of single and mixed stands. In total, in the living biomass of oak forests of Georgia 10,324 Tg C are a ...
bitches; carcinoma; catechol O-methyltransferase; catechol estrogens; disease course; genes; genotype; mammary neoplasms (animal); metabolites; single nucleotide polymorphism; surgery
Abstract:
... The enzyme catechol‐o‐methyltransferase (COMT) is responsible for inactivation of catechol estrogens, which are well‐recognized carcinogenic metabolites. Two single‐nucleotide polymorphisms (SNPs) in canine COMT gene were previously associated with the age of onset of mammary tumours and with the clinical progression of the disease. However, no information is available regarding the impact of othe ...
... The widespread use of antibiotics has led to an increase in the number of strains resistant to major antibacterial pharmaceuticals. Many synthesized quaternary ammonium compounds possess antibacterial, antifungal and antiviral properties. Incorporation of quaternary ammonium moieties into dendrimers represents a promising strategy for the preparation of novel antimicrobial biomaterials. Here, poly ...
adsorbents; adsorption; arsenic; cadmium; catalytic activity; ceric oxide; cerium; chromium; cost effectiveness; decontamination; drinking water; fluorides; human health; kinetics; lead; mercury; metal ions; moieties; porosity; semiconductors; sorption isotherms; surface area; toxicity; water pollution; water treatment
Abstract:
... The presence of contaminants in potable water is a cause of worldwide concern. In particular, the presence of metals such as arsenic, lead, cadmium, mercury, chromium can affect human health. There is thus a need for advanced techniques of water decontamination. Adsorbents based on cerium dioxide (CeO₂), also named ‘ceria,’ have been used to remove contaminants such as arsenic, fluoride, lead and ...
... Species of the family Epipyropidae are infrequently collected due to their ectoparasitic lifestyle and have therefore received little study. Based on our morphological and molecular analyses, all specimens found parasitizing different species of cicadas in China belong to one species, Epipomponia nawai (Dyar). The species Epipomponia oncotympana Yang (nom. invalid.) was found to be identical with ...
... The biological behaviour and prognostic factors of Merkel cell carcinoma (MCC) in 20 cats were studied. The tumours were surgically removed and histopathologically examined. The animals were 8 to 20 years old (median age: 14 years), and the tumours were predominantly located in the neck and head. Follow‐up data were available in 17 cases, and 12 cats died within a year of surgery. The overall medi ...
amputation; bone marrow; bone morphogenetic proteins; children; dogs; drug therapy; flow cytometry; gastrointestinal system; humans; mesenchymal stromal cells; mice; models; neoplasm cells; nephrotoxicity; osteosarcoma; polymerase chain reaction; radiotherapy; stem cells
Abstract:
... Osteosarcoma (OSA) is the most common malignant bone cancer in children and dogs. The therapeutic protocols adopted for dogs and humans are very similar, involving surgical options such as amputation. Besides surgical options, radiotherapy and chemotherapy also are adopted. However, hematologic, gastrointestinal and renal toxicity may occur because of chemotherapy treatments. Recent study clearly ...
... Mast cell tumours (MCTs) are often diagnosed by cytology based on the identification of purple intracytoplasmic granules with methanolic Romanowsky stains, including May‐Grünwald‐Giemsa (MGG). In clinical practice, aqueous rapid stains (RS) are commonly used, but mast cell granules may not stain properly. Aim of this prospective study was to investigate the frequency of MCT hypogranularity with RS ...
death; dogs; histology; mast cells; mitosis; patients; prediction; prognosis; surgery
Abstract:
... A previous study found that minichromosome maintenance protein 7 (MCM7) score was associated with prognosis in dogs with cutaneous mast cell tumours (MCTs) independent of histological grade. The primary aim of this study was to validate this score in a different cohort of dogs focusing exclusively on patients with Patnaik intermediate grade MCTs treated with surgery alone and followed for a minimu ...
... Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Gene therapy utilizes gene delivery to deliver genetic material with the goal of treating a disease or condition in the cell. Actual viral vectors may have side effects, while actual systems using metal nanoparticles for gene delivery are toxic. Therefore, we designed here a biocompatible tri ...
ataxia (disorder); carcinoma; cats; diarrhea; dogs; drug therapy; epithelium; fluorouracil; gastrointestinal system; head and neck neoplasms; humans; ingestion; medical records; nausea; neurotoxicity; neutropenia; otitis; platinum; retrospective studies; thrombocytopenia; vomiting
Abstract:
... 5‐Fluorouracil (5‐FU) is used in combination chemotherapy protocols for human head and neck cancer and other epithelial neoplasms. However, a paucity of literature describing use of this drug in veterinary oncology exists, likely due to previous reports of fatal neurotoxicity in both dogs and cats, mainly due to ingestion of human creams. The primary aim of this retrospective study was to report t ...
Caenorhabditis elegans; Oriental traditional medicine; Sophora; antimicrobial properties; bacteria; ethanol; galactose; gas chromatography-mass spectrometry; glucose; heat stress; in vivo studies; infectious diseases; longevity; oxidative stress; polysaccharides; reproduction; seeds; shrubs; stress tolerance; China
Abstract:
... Sophora moorcroftiana (S. moorcroftiana) is an endemic leguminous dwarf shrub in Tibet, China. Decoctions of the seeds have been used in Chinese folk medicine for dephlogistication, detoxication, and infectious diseases. The present study aimed to investigate the constituent and biological effects of polysaccharides from S. moorcroftiana seeds in Caenorhabditis elegans (C. elegans). Polysaccharide ...
Cornus mas; Oriental traditional medicine; active ingredients; anthocyanins; antioxidants; ascorbic acid; cosmetics; emulsions; fruits; glycerol; inflammation; iridoids; manufacturing; phenolic compounds; plant extracts; raw materials; solvents; vegetable oil
Abstract:
... Dogwood fruits are a valuable source of active ingredients, such as phenolic compounds, vitamin C, iridoids, flavonoids and anthocyanins. Plant extracts and substances derived from latin Cornus mas L. exhibit not only strong antibacterial but also antioxidant and tonicity properties, effectively preventing the development of inflammation in living organisms. In the present study, we attempted to o ...
... The discovery of ordered mesoporous materials in 1992 by Mobil Oil Corporation scientists has opened great opportunities for new applications in many emerging fields such as heterogeneous catalysis, biocatalysis, energy conversion, biosensors, photocatalytic devices and environmental technologies. Porous materials are grouped by the International Union of Pure and Applied Chemistry (IUPAC) into th ...
... Cyclodextrins are among the most remarkable macrocyclic molecules with significant theoretical and practical impacts in chemistry and biology. Cyclodextrins belong to the family of cage molecules due to their structure, which is composed of a hydrophobic cavity that can encapsulate other molecules. Indeed, the most characteristic feature of these compounds is their ability to form inclusion comple ...
... Chromosome data are fundamental in evolution. However, there has been no attempt to synthesize and evaluate the significance of such information from a phylogenetic perspective in the giant genus Solanum, which was the aim of this work. New and published information of the main cytotaxonomic features (chromosome number, polyploidy, total length of the haploid complement, mean chromosome length, me ...
... Beans, an excellent source of dietary fiber and protein, have potential for lowering glycemic load. Prepared meals with high dietary fiber and low glycemic load were rare in a market survey in Baton Rouge, LA. The purpose of this research was to increase fiber and decrease glycemic load in ravioli through substitution with bean flour from pinto, navy, or black beans mixed with wheat flour. Navy be ...
... Present investigation describes a micropropagation protocol for pomegranate variety ‘Bhagwa’ using axillary buds as explants. Axenic cultures were established using sequential application of carbendazim-50%, cefotaxime, kanamycin, streptocycline and mercuric chloride (HgCl2). Among the twenty five different treatments tested for control of exudation, translocation of the explants five times at a r ...
... Rice is one of the agronomically and nutritionally important cereal crops. It provides food for more than 50% of the world's population. However, the yield of rice crop is decreased by the salinity stress. This can be overcome by the development of salt-resistant rice varieties. In this study salt resistant callus cultures were developed by the somatic hybridization between Oryza sativa and Myrios ...
... ICAR-Directorate of Cashew Research is the nodal agency for conducting cashew research and manages the largest field gene bank in India. Cashew is a perennial tree and needs more land and other resources to maintain accessions. Conservation through seeds is not feasible because of cross-pollination. Tissue culture efforts to regenerate plants from mature explants are not successful. Therefore, eff ...
aqueous solutions; desalination; distillation; drinking water; energy costs; groundwater; osmosis; surface water; wastewater; water shortages
Abstract:
... Membrane technology has become a common separation technology over the past decennia. Membranes are used more and more for the production of drinkable water from groundwater, surface water and wastewater. Membranes are now competitive versus conventional techniques. Desalination is predominantly used to eradicate the problem of water scarcity. The sustainability of all desalination processes depen ...
... The diagnostic accuracy of contrast‐enhanced CT for detection of cervical lymph node metastasis in dogs is unknown. The purpose of this retrospective, observational, diagnostic accuracy study was to assess the efficacy of CT for detection of mandibular and medial retropharyngeal lymph node metastasis in dogs. Histopathology of dogs with cancer of the head, CT and bilateral mandibular and medial re ...