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1. 1H-Pteridine-2,4-dione (lumazine): a new MALDI matrix for complex (phospho)lipid mixtures analysis

Author:
Calvano, Cosima D.; Carulli, Saverio; Palmisano, Francesco
Source:
Analytical and bioanalytical chemistry 2010 v.398 no.1 pp. 499-507
ISSN:
1618-2642
Subject:
2,5-dihydroxybenzoic acid; absorption; cations; desorption; eggs; hens; ionization; mass spectrometry; milk; phosphatidylcholines; phosphatidylethanolamines; phosphatidylglycerols; phosphatidylinositols; phosphatidylserines; soymilk; sphingomyelins
Abstract:
... Nowadays, matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry represents an emerging and versatile tool for analysis of lipids. However, direct (i.e., with no previous separation of lipid classes) analysis of crude extracts containing a complex mixture of lipids (a problem typically encountered in shotgun lipidomics) is still a quite challenging task using a conven ...
DOI:
10.1007/s00216-010-3927-x
PubMed:
20593166

2. 2,5‐Dihydroxybenzoic acid solution in MALDI‐MS: ageing and use for mass calibration

Author:
Anu Teearu; Signe Vahur; Uku Haljasorg; Ivo Leito; Tõiv Haljasorg; Lauri Toom
Source:
Journal of mass spectrometry 2014 v.49 no.10 pp. 970-979
ISSN:
1076-5174
Subject:
2,5-dihydroxybenzoic acid; Fourier transform infrared spectroscopy; acetonitrile; chemical degradation; matrix-assisted laser desorption-ionization mass spectrometry; spectral analysis; spectrometers
Abstract:
... 2,5‐Dihydroxybenzoic acid (DHB) is one of the most widely used and studied matrix compounds in matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry. However, the influence of ageing of the DHB solution on the MALDI mass spectra has not been yet systematically studied. In this work, the possible changes occurring in the acidified acetonitrile/water solution of the MALDI matrix comp ...
DOI:
10.1002/jms.3395

3. 2-(2-Aminoethylamino)-5-nitropyridine as a basic matrix for negative-mode matrix-assisted laser desorption/ionization analysis of phospholipids

Author:
Lorkiewicz, Pawel; Cecilia Yappert, M.
Source:
Journal of mass spectrometry 2009 v.44 no.1 pp. 137-143
ISSN:
1076-5174
Subject:
2,5-dihydroxybenzoic acid; automation; desorption; ethanolamine; ionization; mass spectrometry; mixtures; phosphatidylcholines; phosphatidylserines; soybeans; sphingomyelins; zwitterions
Abstract:
... Fast and easy analysis of phospholipids (PLs) by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has been well demonstrated. However, when using common organic matrices, such as 2,5-dihydroxybenzoic acid (DHB), the detection of most PL classes in positive-ion mode is difficult when PLs containing zwitterionic groups, such as phosphatidylcholines (PCs) and sphingomyelins (S ...
DOI:
10.1002/jms.1483

4. 2-Phenyl-3-(p-aminophenyl) Acrylonitrile: A Reactive Matrix for Sensitive and Selective Analysis of Glycans by MALDI-MS

Author:
Ling Ling; Chunsheng Xiao; Yao Ma; Liyan Jiang; Sheng Wang; Liming Guo; Shimei Jiang; Xinhua Guo
Source:
Analytical chemistry 2019 v.91 no.14 pp. 8801-8807
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; aldehydes; analytical specificity; blood serum; desorption; detection limit; glycoproteins; humans; ionization; matrix-assisted laser desorption-ionization mass spectrometry; nitriles; peptides; polysaccharides; tandem mass spectrometry
Abstract:
... Analysis of glycans by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is usually limited by the intrinsically low abundance and low ionization efficiency of glycans. Aiming to enhance the ionization efficiency of glycans and simplify the sample preparation procedure during MALDI-MS analysis, we reported herein a novel reactive matrix, 2-phenyl-3-(p-aminophenyl) acrylonitr ...
DOI:
10.1021/acs.analchem.9b01434

5. 3,4-Dimethoxycinnamic Acid as a Novel Matrix for Enhanced In Situ Detection and Imaging of Low-Molecular-Weight Compounds in Biological Tissues by MALDI-MSI

Author:
Huixin He; Liang Qin; Yawen Zhang; Manman Han; Jinming Li; Yaqin Liu; Kaidi Qiu; Xiaoyan Dai; Yanyan Li; Maomao Zeng; Huihong Guo; Yijun Zhou; Xiaodong Wang
Source:
Analytical chemistry 2019 v.91 no.4 pp. 2634-2643
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; absorption; alkaloids; brain; desorption; flavonoids; graphene oxide; image analysis; ionization; lipids; liquid chromatography; liver; metabolites; nanosilver; oligopeptides; plant tissues; rats; seeds; tandem mass spectrometry
Abstract:
... Low-molecular-weight (low-MW) compounds have many essential functions in biological processes, and the molecular imaging of as many low-MW compounds as possible is critical for understanding complex biological processes. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is an emerging molecular-imaging technology that enables determination of the spatial distributio ...
DOI:
10.1021/acs.analchem.8b03522

6. 3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging

Author:
Bin Li; Ruiyang Sun; Andrew Gordon; Junyue Ge; Ying Zhang; Ping Li; Hua Yang
Source:
Analytical chemistry 2019 v.91 no.13 pp. 8221-8228
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; absorption; biochemical pathways; biomarkers; brain; central nervous system diseases; desorption; fatty acids; image analysis; ionization; matrix-assisted laser desorption-ionization mass spectrometry; metabolites; mice; nucleotides; sodium; sphingolipids
Abstract:
... In many aspects of the matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) technique, the discovery of new MALDI matrixes has been a major task for the improvement of ionization efficiency, signal intensity, and molecular coverage. In this work, five analog compounds, including phthalhydrazide, 3-aminophthalhydrazide (3-APH or luminol) and its sodium salt, 4-aminophth ...
DOI:
10.1021/acs.analchem.9b00803

7. 3-Aminoquinoline/p-Coumaric Acid as a MALDI Matrix for Glycopeptides, Carbohydrates, and Phosphopeptides

Author:
Fukuyama Yuko; Funakoshi Natsumi; Takeyama Kohei; Hioki Yusaku; Nishikaze Takashi; Kaneshiro Kaoru; Kawabata Shin-ichirou; Iwamoto Shinichi; Tanaka Koichi
Source:
Analytical chemistry 2014 v.86 no.4 pp. 1937-1942
ISSN:
1520-6882
Subject:
sialic acids; sulfates; glycosylation; biomarkers; 2,5-dihydroxybenzoic acid; dissociation; p-coumaric acid; phosphates; phosphorylation; mass spectrometry; glycopeptides
Abstract:
... Glycosylation and phosphorylation are important post-translational modifications in biological processes and biomarker research. The difficulty in analyzing these modifications is mainly their low abundance and dissociation of labile regions such as sialic acids or phosphate groups. One solution in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry is to improve matrices for gly ...
DOI:
10.1021/ac4037087

8. 4‐Chloro‐α‐cyanocinnamic acid is an efficient soft matrix for cyanocobalamin detection in foodstuffs by matrix‐assisted laser desorption/ionization mass spectrometry (MALDI MS)

Author:
Cosima Damiana Calvano; Giovanni Ventura; Francesco Palmisano; Tommaso R.I. Cataldi
Source:
Journal of mass spectrometry 2016 v.51 no.9 pp. 841-848
ISSN:
1076-5174
Subject:
2,5-dihydroxybenzoic acid; chemical bonding; desorption; egg yolk; energy; fish; hens; ionization; ions; ligands; liver; mass spectrometry; meat; nitroanilines; qualitative analysis; sodium; vitamin B12
Abstract:
... 4‐Chloro‐α‐cyanocinnamic acid (ClCCA) is a very useful matrix able to give the protonated adduct [M+H]⁺ of intact cyanocobalamin (CNCbl) as the base peak (m/z 1355.58) in matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry (MS). The only fragment observed is [M‐CN + H]⁺• formed through the facile •CN neutral loss reflecting the fairly low Co–C bond energy. All other investigated ...
DOI:
10.1002/jms.3817

9. Accumulation of Polyphenolic Compounds and Osmolytes under Dehydration Stress and Their Implication in Redox Regulation in Four Indigenous Aromatic Rice Cultivars

Author:
Nivedita Dey; Soumen Bhattacharjee
Source:
Rice science 2020 v.27 no.4 pp. 329-344
ISSN:
1672-6308
Subject:
2,5-dihydroxybenzoic acid; Oryza sativa; apigenin; benzoic acid; betaine; biomarkers; caffeic acid; catechin; chlorogenic acid; confocal microscopy; cultivars; drought tolerance; gallic acid; homeostasis; hydrogen peroxide; indigenous species; kaempferol; myricetin; naringin; oxidation; p-coumaric acid; polyethylene glycol; polyphenols; potassium; proline; protocatechuic acid; quercetin; rice; rutin; salicylic acid; seeds; sinapic acid; superoxide anion; syringic acid; thiobarbituric acid-reactive substances; thiols; water stress; India
Abstract:
... Present work was undertaken to screen some drought tolerant indigenous aromatic rice cultivars (IARCs), commonly cultivated in West Bengal, India, based on their capacity to produce osmolytes, redox-sensitive phenolic acids and flavonoids, as contrivances for redox-regulation under drought stress. Polyethylene glycol induced post imbibitional dehydration stress mediated changes in redox regulatory ...
DOI:
10.1016/j.rsci.2020.05.008

10. Alkali-hydroxide-doped matrices for structural characterization of neutral underivatized oligosaccharides by MALDI time-of-flight mass spectrometry

Author:
Tzeng, Yan-Kai; Zhu, Zhiqiang; Chang, Huan-Cheng
Source:
Journal of mass spectrometry 2009 v.44 no.3 pp. 375-383
ISSN:
1076-5174
Subject:
2,5-dihydroxybenzoic acid; aqueous solutions; beta-cyclodextrin; derivatization; desorption; dextran; hexoses; ionization; ions; isomers; lithium; mass spectrometry; mixing; oligosaccharides; sodium hydroxide
Abstract:
... We report new approaches using alkali-hydroxide-doped matrices to facilitate structural characterization of neutral underivatized oligosaccharides by matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) MS. The approaches involved pretreatment of the analytes with NaOH or LiOH in aqueous solution, followed by mixing them with MALDI matrices prior to MS analysis. It was found th ...
DOI:
10.1002/jms.1515

11. Alkylated Dihydroxybenzoic Acid as a MALDI Matrix Additive for Hydrophobic Peptide Analysis

Author:
Fukuyama Yuko; Tanimura Ritsuko; Maeda Kazuki; Watanabe Makoto; Kawabata Shin-Ichirou; Iwamoto Shinichi; Izumi Shunsuke; Tanaka Koichi
Source:
Analytical chemistry 2012 v.84 no.9 pp. 4237-4243
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; desorption; hydrophilicity; hydrophobicity; image analysis; ionization; mass spectrometry; peptides; phosphorylase
Abstract:
... Hydrophobic peptides are generally difficult to detect using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) because the majority of MALDI matrixes are hydrophilic and therefore have a low affinity for hydrophobic peptides. Here, we report on a novel matrix additive, o-alkylated dihydroxybenzoic acid (ADHB), which is a 2,5-dihydroxybenzoic acid (DHB) derivative incorporati ...
DOI:
10.1021/ac300540r

12. Alleviative effects of litchi (Litchi chinensis Sonn.) flower on lipid peroxidation and protein degradation in emulsified pork meatballs

Author:
Yi Ding; Sheng-Yao Wang; Deng-Jye Yang; Ming-Hsu Chang; Yi-Chen Chen
Source:
Yàowù shípǐn fēnxī 2015 v.23 no.3 pp. 501-508
ISSN:
1021-9498
Subject:
2,5-dihydroxybenzoic acid; Litchi chinensis; additives; antioxidants; centrifugation; cooked foods; drugs; epicatechin; flowers; frozen storage; hydroquinone; lipid peroxidation; lipids; oxidation; physicochemical properties; pork; powders; protein degradation; sensory evaluation; storage time; texture; thiobarbituric acid-reactive substances; thiols; water holding capacity
Abstract:
... To avoid or retard the lipid peroxidation of meat products, antioxidants are commonly added. Considering the safety and health of additives in meat products, consumers prefer natural antioxidants rather than synthetic ones. Gentisic acid and epicatechin were identified as the major phenolic acid and flavonoid, respectively, of litchi flowers (LFs). The physicochemical properties of pork meatballs ...
DOI:
10.1016/j.jfda.2015.02.004

13. Amine-Functionalized Sol–Gel-Based Lab-in-a-Pipet-Tip Approach for the Fast Enrichment and Specific Purification of Phosphopeptides in MALDI-MS Applications

Author:
Atakay Mehmet; Çelikbıçak Ömür; Salih Bekir
Source:
Analytical chemistry 2012 v.84 no.6 pp. 2713-2720
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; beta-casein; bovine serum albumin; detection limit; glass fibers; pH; peptides; phosphopyruvate hydratase; phosphoric acid; purification methods; skim milk
Abstract:
... Amine-functionalized sol–gels were investigated for the enrichment and purification of phosphopeptides from digested protein mixture solutions. Tetramethylorthosilicate (TMOS) and N′[3-(trimethoxysilyl)-propyl]-diethylenetriamine (TPDA) were used in a 1:1 mole ratio in the production of amine-functionalized sol–gels. The sol–gel network was then used for phosphopeptide enrichment. Phosphopeptide e ...
DOI:
10.1021/ac203008u

14. Ammonium Sulfate Improves Detection of Hydrophilic Quaternary Ammonium Compounds through Decreased Ion Suppression in Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Author:
Sugiyama Eiji; Masaki Noritaka; Matsushita Shoko; Setou Mitsutoshi
Source:
Analytical chemistry 2015 v.87 no.22 pp. 11176-11181
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; ammonium sulfate; bioactive properties; brain; carnitine; choline; derivatization; desorption; hydrophilicity; image analysis; ionization; matrix-assisted laser desorption-ionization mass spectrometry; phosphatidylcholines; potassium
Abstract:
... Hydrophilic quaternary ammonium compounds (QACs) include derivatives of carnitine (Car) or choline, which are known to have essential bioactivities. Here we developed a technique for improving the detection of hydrophilic QACs using ammonium sulfate (AS) in matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS). In MALDI mass spectrometry for brain homogenates, the addit ...
DOI:
10.1021/acs.analchem.5b02672

15. Analysis of Initial Reactions of MALDI Based on Chemical Properties of Matrixes and Excitation Condition

Author:
Lai Yin-Hung; Wang Chia-Chen; Chen Chiu Wen; Liu Bo-Hong; Lin Sheng Hsien; Lee Yuan Tseh; Wang Yi-Sheng
Source:
Journal of physical chemistry 2012 v.116 no.32 pp. 9635-9643
ISSN:
1520-5207
Subject:
2,5-dihydroxybenzoic acid; absorption; desorption; energy; fluorescence; ionization; ions; photons; physicochemical properties; wavelengths
Abstract:
... This investigation concerns the initial chemical reactions that affect the ionization of matrixes in matrix-assisted laser desorption/ionization (MALDI). The study focuses on the relaxations of photon energy that occur on a comparable time scale to that of ionization, in which the available laser energy is shared and the ionization condition is changed. The relaxations include fluorescence, fragme ...
DOI:
10.1021/jp304709q

16. Analysis of phytochemical composition of leaf extract of sacred fig (Ficus religiosa L.) by UPLC-QqQ-MS and assessment of their hepatocurative potential in mouse model

Author:
Udhayaraj Suriyakalaa; Devanesan Arul Ananth; Rajamanickam Ramachandran; Devaraj Sankarganesh; Jayaraman Angayarkanni; Zipora Tietel; Shanmugam Achiraman
Source:
South African journal of botany 2022 pp. -
ISSN:
0254-6299
Subject:
2,5-dihydroxybenzoic acid; Ficus religiosa; antioxidant activity; bilirubin; carbon tetrachloride; catechin; chemical constituents of plants; creatinine; ethnobotany; figs; hepatotoxicity; histopathology; leaf extracts; leaves; liver; mass spectrometry; mice; polyphenols; protocatechuic acid; quinic acid; rutin; ultra-performance liquid chromatography; urea
Abstract:
... In view of their remarkable pharmacological properties and bioactivities Ficus sp. are used in traditional medicines. Ficus religiosa is richly endowed with ethnobotanical values and it is a promising entity in various medicinal formulations; however, comprehensive phytochemical identification and quantification of F. religiosa using Ultra Performance Liquid Chromatography Triple Quadrupole Mass S ...
DOI:
10.1016/j.sajb.2022.01.007

17. Analyte-Size-Dependent Ionization and Quantification of Monosaccharides in Human Plasma Using Cation-Exchanged Smectite Layers

Author:
Ding Yuqi; Kawakita Kento; Xu Jiawei; Akiyama Kazuhiko; Fujino Tatsuya
Source:
Analytical chemistry 2015 v.87 no.15 pp. 7944-7950
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; desorption; humans; ionization; mass spectrometry; molecular weight; monosaccharides; polymers; quantitative analysis; smectite
Abstract:
... Smectite, a synthetic inorganic polymer with a saponite structure, was subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Typical organic matrix molecules 2,4,6-trihydroxyacetophenone (THAP) and 2,5-dihydroxybenzoic acid (DHBA) were intercalated into the layer spacing of cation-exchanged smectite, and the complex was used as a new matrix for laser desorption/ion ...
DOI:
10.1021/acs.analchem.5b01770

18. Analytical Methods Applied to Assess Chemical Composition, Nutritional Value and In Vitro Bioactivities of Terfezia olbiensis and Terfezia claveryi from Turkey

Author:
İbrahim Kıvrak
Source:
Food analytical methods 2015 v.8 no.5 pp. 1279-1293
ISSN:
1936-9751
Subject:
2,5-dihydroxybenzoic acid; Terfezia; analytical methods; benzoic acid; beta-carotene; bioactive properties; bleaching; decolorization; dietary supplements; enzymes; essential amino acids; ethyl acetate; food additives; free amino acids; free radical scavengers; free radicals; fructose; heavy metals; hexane; industry; ingredients; lipid peroxidation; mannitol; minerals; mushrooms; nutritive value; protocatechuic acid; rhamnose; shelf life; trehalose; truffles
Abstract:
... In this study, nutritional value, free amino acids, phenolic and sugar compounds, mineral and heavy metal contents of truffles, Terfezia olbiensis, and Terfezia claveryi from Turkey were chemically characterized using different analytical methods. In vitro antioxidant characteristics, β-carotene bleaching assay, 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, ABTS cation ra ...
DOI:
10.1007/s12161-014-0009-2

19. Analytical determination and pharmacokinetics of major metabolites of carbasalate calcium in broilers following oral administration

Author:
WANG, X.; HUANG, L.-L.; CHEN, D.-M.; IHSAN, A.; YUAN, Z.-H.
Source:
Journal of veterinary pharmacology and therapeutics 2011 v.34 no.4 pp. 410-416
ISSN:
0140-7783
Subject:
2,5-dihydroxybenzoic acid; anti-inflammatory agents; aspirin; body weight; calcium; metabolites; oral administration; pharmacokinetics; salicylic acid
Abstract:
... Wang, X., Huang, L.-L., Chen, D.-M., Ihsan, A., Yuan, Z.-H. Analytical determination and pharmacokinetics of major metabolites of carbasalate calcium in broilers following oral administration. J. vet. Pharmacol. Therap.34, 410-416. As a newer anti-inflammatory agent, carbasalate calcium is used in various animal species. In this study, the pharmacokinetics of carbasalate calcium was investigated i ...
DOI:
10.1111/j.1365-2885.2010.01250.x
PubMed:
21091728

20. Anthelmintic activity of phenolic acids from the axlewood tree Anogeissus leiocarpus on the filarial nematode Onchocerca ochengi and drug-resistant strains of the free-living nematode Caenorhabditis elegans

Author:
D. Ndjonka; E.D. Abladam; B. Djafsia; I. Ajonina-Ekoti; M.D. Achukwi; E. Liebau
Source:
Journal of helminthology 2014 v.88 no.4 pp. 481-488
ISSN:
1475-2697
Subject:
2,5-dihydroxybenzoic acid; Anogeissus leiocarpa; Caenorhabditis elegans; Onchocerca ochengi; adults; albendazole; drug resistance; drugs; ellagic acid; free-living nematodes; gallic acid; ivermectin; lethal concentration 50; levamisole; microfilariae; models; nematode infections; parasites; phenols; toxicity; trees
Abstract:
... The effect of three phenols (ellagic, gentisic and gallic acids) from the axlewood tree Anogeissus leiocarpus on Onchocerca ochengi and drug-resistant strains of Caenorhabditis elegans, a model organism for research on nematode parasites, is investigated. Worms were incubated in different concentrations of phenols and their survival was monitored after 48 h. Among the three acids, ellagic acid str ...
DOI:
10.1017/S0022149X1300045X
PubMed:
23768773

21. Anti-apoptotic effects of novel phenolic antioxidant isolated from the Pacific oyster (Crassostrea gigas) on cultured human hepatocytes under oxidative stress

Author:
Hirotoshi Fuda; Mitsugu Watanabe; Shu-Ping Hui; Sae Joko; Hiroaki Okabe; Shigeki Jin; Seiji Takeda; Emiko Miki; Takayuki Watanabe; Hitoshi Chiba
Source:
Food chemistry 2015 v.176 pp. 226-233
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; Crassostrea gigas; DNA; antioxidants; apoptosis; ascorbic acid; butylated hydroxytoluene; catechin; cell viability; chlorogenic acid; cytotoxicity; daidzein; docosahexaenoic acid; eicosapentaenoic acid; flow cytometry; hepatocytes; hepatoprotective effect; humans; mass spectrometry; matairesinol; necrosis; oxidative stress; oyster meat; oysters; polyphenols
Abstract:
... The antioxidant, and hepatoprotective properties of 3,5-dihydroxy-4-methoxybenzyl alcohol (DHMBA), a natural phenolic antioxidant isolated from the Pacific oyster, were defined using cultured human hepatocyte-derived cells (C3A). DHMBA showed no cytotoxicity at 62.5–500μM, as well as chlorogenic acid (CGA), vitamin C, and vitamin E. However, butylated hydroxytoluene, eicosapentaenoic acid, docosah ...
DOI:
10.1016/j.foodchem.2014.12.066

22. Anti-inflammatory glycosides isolated from the aerial parts of Morinda parvifolia

Author:
Xianming Su; Jian Zhang; Fenghua Li; Changkang Li; Jia Fu; Baoming Li; Ruoyun Chen; Jie Kang
Source:
Phytochemistry letters 2019 v.33 pp. 55-60
ISSN:
1874-3900
Subject:
2,5-dihydroxybenzoic acid; Croton; Morinda; aerial parts; anti-inflammatory activity; benzoic acid; ears; edema; ethyl acetate; gene expression; glycosides; herbal medicines; indigestion; inhibitory concentration 50; interleukin-6; mice; oils; spectral analysis; tracheitis
Abstract:
... The plant Morinda parvifolia is traditionally used as an herbal medicine for the treatment of dyspepsia, tracheitis, and coughing. The ethyl acetate extract of the aerial parts of M. parvifolia showed significant inhibition against ear edema in mice induced by croton oil (36.4% inhibition). Four undescribed glycosides, 2-hydroxymethyl anthraquinone-3-O-β-primeveroside, p-hydroxy benzoic acid 4-O-β ...
DOI:
10.1016/j.phytol.2019.07.008

23. Anti-influenza mechanism of phenolic phytochemicals from Canarium album (Lour.) DC. leaf extract

Author:
Mengjie Xiao; Bobby Lim-Ho Kong; Yahui Zhang; Yinhua Yang; Jiaqi Lu; Hung-Kay Lee; Fei Cao; Pang-Chui Shaw
Source:
Journal of ethnopharmacology 2022 v.292 pp. 115175
ISSN:
0378-8741
Subject:
2,5-dihydroxybenzoic acid; Canarium album; Influenza A virus; circular dichroism spectroscopy; flavonoids; glycosides; heat; hemagglutination; hemagglutinins; influenza; leaf extracts; leaves; lungs; moieties; phenotype; probability; reverse genetics; sialidase; toxic substances; traditional medicine; viruses
Abstract:
... Canarium album (Lour.) DC. belongs to the Burseraceae family. Its leaf, named as Ganlanye (GLY), was recorded to treat warm disease symptoms via clearing lung heat and toxicants in medical classics. Its aqueous extract had anti-influenza activity in our previous phenotypic screening. However, its active components and mechanism were not identified. We aim to isolate the anti-influenza phytochemica ...
DOI:
10.1016/j.jep.2022.115175

24. Anticholinesterase Activity of Phenolic Acids and their Derivatives

Author:
Dominik Szwajgier
Source:
Zeitschrift für Naturforschung 2014 v.68 no.3-4 pp. 125-132
ISSN:
1865-7125
Subject:
2,5-dihydroxybenzoic acid; acetylcholine; caftaric acid; cholinesterase; esters; molecular weight; nordihydroguaiaretic acid; rosmarinic acid
Abstract:
... The ability of 36 phenolic acids and their derivatives to inhibit acetyl- and butyrylcholinesterase was studied. The most efficient acetylcholine inhibitors were: carnosic acid = gentisic acid > 3-hydroxy-4-methoxycinnamic acid = ethyl ferulate = ethyl vanillate = nordihydroguaiaretic acid > ethyl 4-hydroxybenzoate = methyl ferulate. The order of effectiveness towards butyrylcholinesterase was: ca ...
DOI:
10.1515/znc-2013-3-408

25. Antimicrobial activity of ozone. Effectiveness against the main wine spoilage microorganisms and evaluation of impact on simple phenols in wine

Author:
R. Guzzon; T. Nardin; O. Micheletti; G. Nicolini; R. Larcher
Source:
Australian journal of grape and wine research 2013 v.19 no.2 pp. 180-188
ISSN:
1322-7130
Subject:
2,5-dihydroxybenzoic acid; antimicrobial properties; ethanol; fermentation; microbial contamination; microorganisms; oak barrels; oak chips; organic matter; ozone; phenols; spoilage; wine industry; wines; wood
Abstract:
... BACKGROUND AND AIMS: Microbial contamination affects winemaking, especially after fermentation, e.g. wine ageing in barrels or in contact with oak pieces, when spoilage microbes find an environment favourable for their development. Ozone was evaluated as a sanitising agent in order to assess its potential to prevent microbial spoilage occurring during ageing of wine in barrels using a model system ...
DOI:
10.1111/ajgw.12018

26. Antioxidant activities, total phenolics and HPLC analyses of the phenolic compounds of extracts from common Mediterranean plants

Author:
Taha M. Rababah; Khalil I. Ereifej; Ranya B. Esoh; Muhammad H. Al-u'datt; Mohammad A. Alrababah; W. Yang
Source:
Natural product research 2011 v.25 no.6 pp. 596-605
ISSN:
1478-6427
Subject:
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; Petroselinum crispum; Salvia officinalis; antioxidant activity; antioxidants; benzoic acid; caffeic acid; catechin; chlorogenic acid; correlation; epicatechin; gallic acid; high performance liquid chromatography; parsley; plant extracts; protocatechuic acid; sage; syringic acid; vanillic acid; Jordan
Abstract:
... In this study, the total phenolic amounts and antioxidant activities of plant extracts obtained from some common Mediterranean plant species collected from different places in Jordan were determined. The phenolic constituents of these extracts were also determined using HPLC. The total phenolic amounts ranged from 52.8 to 876.9 mg GAE per 100 g dry material. The antioxidant activities were evaluat ...
DOI:
10.1080/14786419.2010.488232

27. Antioxidant activity and chemical difference in fruit of different Actinidia sp.

Author:
Piotr Latocha; Tomasz Krupa; Rafał Wołosiak; Elwira Worobiej; Jacek Wilczak
Source:
International journal of food sciences and nutrition 2010 v.61 no.4 pp. 381-394
ISSN:
1465-3478
Subject:
2,5-dihydroxybenzoic acid; Actinidia arguta; Actinidia deliciosa; Actinidia kolomikta; Actinidia melanandra; antioxidant activity; ascorbic acid; carotenoids; chlorophyll; flavonoids; fruits; high performance liquid chromatography; nutrition; tannins
Abstract:
... The present research aimed at evaluating the vitamin C, total phenolic content (TPC), phenolic compounds, carotenoids, and chlorophyll contents, as well as antioxidant activity (AAC) of six Actinidia species fruit. Vitamin C, phenolic compounds, carotenoids and chlorophylls were measured using high-performance liquid chromatography. TPC was determined using the Folin–Ciocalteau reagent, and AAC us ...
DOI:
10.3109/09637480903517788

28. Antioxidant and Anti‐inflammatory Activities of Methanol Extracts of Tremella fuciformis and Its Major Phenolic Acids

Author:
Hua Li; Hee‐Seok Lee; Su‐Hwan Kim; BoKyung Moon; Chan Lee
Source:
Journal of food science 2014 v.79 no.4 pp. C460
ISSN:
0022-1147
Subject:
2,5-dihydroxybenzoic acid; Tremella fuciformis; antioxidant activity; chloroform; free radical scavengers; low density lipoprotein; methanol; mushrooms; nitric oxide; nitric oxide synthase; oxidation
Abstract:
... Methanol extract subfractions of the edible white jelly mushroom (Tremella fuciformis), were assessed for the following antioxidant properties: ABTS⁺ radical scavenging activity, 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging activity, and inhibitory activity of human low‐density lipoprotein (LDL) oxidation. Among the subfractions tested, the chloroform subfraction exhibited the strongest ...
DOI:
10.1111/1750-3841.12393
PubMed:
24547933

29. Antioxidant capacity and interaction of endogenous phenolic compounds from tea seed oil

Author:
Guoyan Liu; Wenqi Zhu; Sitong Li; Wanli Zhou; Huijuan Zhang; Jing Wang; Xiaofang Liu; Jixian Zhang; Li Liang; Xin Xu
Source:
Food chemistry 2022 v.376 pp. 131940
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; antioxidants; ethanol; food chemistry; lipid peroxidation; oxidative stability; quercetin; rancidity; seed oils; tartaric acid
Abstract:
... Endogenous phenols play a significant role in delaying oil rancidity. In this study, the profile of 22 endogenous phenols was determined from tea seed oil by UPLC-MS/MS, of which 15 phenols were identified for the first time. Then seven phenols with high content and strong antioxidant capacity were selected to investigate interaction using the DPPH· and Rancimat. It was found that the interaction ...
DOI:
10.1016/j.foodchem.2021.131940

30. Antioxidative Effects of Phenolic Compounds of Mushroom Mycelia in Simulated Regions of the Human Colon, In Vitro Study

Author:
Emanuel Vamanu; Diana Pelinescu; Ionela Avram
Source:
Polish journal of food and nutrition sciences 2017 v.68 no.1 pp. 83-90
ISSN:
2083-6007
Subject:
2,5-dihydroxybenzoic acid; Agaricus bisporus; Bifidobacterium; Enterobacteriaceae; Lactobacillus; Lentinula edodes; Pleurotus ostreatus; antioxidant activity; antioxidants; basidia; bioactive compounds; caffeic acid; colon; fermentation; freeze drying; high performance liquid chromatography; humans; metabolites; mushrooms; mycelium; polyphenols
Abstract:
... Many compounds in mushrooms are biologically active; however, the in vivo actions of their metabolites are poorly understood. An in vitro system, GIS1, was used to simulate the fermentation action of microbiota in each colon region. We used MycoPo, a natural product obtained from the lyophilized mycelia of different Pleurotus ostreatus species to determine the biological effects in human-colon reg ...
DOI:
10.1515/pjfns-2017-0010

31. Antioxidative and anti-inflammatory effects of polyphenol-rich litchi (Litchi chinensis Sonn.)-flower-water-extract on livers of high-fat-diet fed hamsters

Author:
Yuan-Yen Chang; Deng-Jye Yang; Chih-Hsien Chiu; Yi-Ling Lin; Jr-Wei Chen; Yi-Chen Chen
Source:
Journal of functional foods 2013 v.5 no.1 pp. 44-52
ISSN:
1756-4646
Subject:
2,5-dihydroxybenzoic acid; Litchi chinensis; anti-inflammatory activity; antioxidant activity; blood lipids; drinking; epicatechin; hamsters; high fat diet; histopathology; liver; protective effect; thiobarbituric acid-reactive substances
Abstract:
... Gentisic acid and epicatechin are two major compounds in phenolic acids and flavonoids of litchi-flower-water extracts (LFWEs), respectively. Increased (p<0.05) serum lipids and liver size/lipid, damage/inflammatory indices, TBARS value, CRP level, MMP-9 activity, and decreased (p<0.05) liver GSH and TEAC levels, and SOD, CAT and GSH-Px activities were observed in high-fat-diet fed hamsters compar ...
DOI:
10.1016/j.jff.2012.08.002

32. Application of dyes as doping agents in MALDI-MS matrices for the signal enhancement of proteins

Author:
Arslan Ali; Najia Shahid; Syed Ghulam Musharraf
Source:
RSC advances 2017 v.7 no.11 pp. 6598-6604
ISSN:
2046-2069
Subject:
2,5-dihydroxybenzoic acid; bovine serum albumin; casein; egg albumen; erythrosine; honey; insulin; myoglobin; peptides; sinapic acid
Abstract:
... Matrix Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS) is considered as a technique of choice for analysing proteins and peptides. Several modifications have been proposed to increase the sensitivity of MALDI-MS procedure so that low abundant proteins can be targeted. The present work describes the study of the possible increase in MALDI-MS sensitivity by increasing the ion gener ...
DOI:
10.1039/c6ra27156a

33. Application of ionic liquid matrices in spectral analysis of poly(lactide) - solid state NMR spectroscopy versus matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry

Author:
Beata Miksa; Marek Sochacki; Jan Libiszowski; Andrzej Duda; Wlodzimierz Ciesielski; Marek J. Potrzebowski
Source:
Analytical methods 2012 v.4 no.2 pp. 377-383
ISSN:
1759-9679
Subject:
2,5-dihydroxybenzoic acid; amines; benzoic acid; carbon; desorption; droplets; indole acetic acid; ionic liquids; isomerization; liquids; matrix-assisted laser desorption-ionization mass spectrometry; melting; nuclear magnetic resonance spectroscopy; polylactic acid; signal-to-noise ratio; spectral analysis; stable isotopes; temperature; thermal stability
Abstract:
... The work presented here shows the complementarity of Solid State NMR (SS NMR) spectroscopy and Matrix-Assisted Laser Desorption/Ionization-time-of-flight (MALDI-TOF) mass spectrometry in spectral analysis of poly(l-lactide) (PLLA) using second-generation ionic liquid matrices (ILM II) prepared from N,N-diisopropylethylamine (DEA) and DHB (2,5-dihydroxybenzoic acid), IAA (3-indoleacrylic acid), and ...
DOI:
10.1039/c2ay05332b

34. Application of the van’t Hoff dependences in the characterization of molecularly imprinted polymers for some phenolic acids

Author:
Natalia Denderz; Jozef Lehotay
Source:
Journal of chromatography 2012 v.1268 no. pp. 44-52
ISSN:
0021-9673
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Fourier transform infrared spectroscopy; acetonitrile; acrylamides; gallic acid; high performance liquid chromatography; methanol; molecular imprinting; polymers; protocatechuic acid; quercetin; reflectance; scanning electron microscopy; sorption; syringic acid; temperature; thermodynamics; vanillic acid
Abstract:
... Thermodynamic analysis was used to quantify the contribution of entropic and enthalpic terms of the binding processes of selected phenolic acids (PAs), quercetin and diperodon on series of molecularly imprinted polymers (MIPs). All polymers were prepared using acrylamide as functional monomer and acetonitrile as a porogen. The following PAs were used as templates – gallic (GA), gentisic (GeA), syr ...
DOI:
10.1016/j.chroma.2012.10.025

35. Assessing Anticancer Potential of Blueberry Flavonoids, Quercetin, Kaempferol, and Gentisic Acid, Through Oxidative Stress and Apoptosis Parameters on HCT-116 Cells

Author:
Ebru Demirel Sezer; Latife Merve Oktay; Elif Karadadaş; Hikmet Memmedov; Nur Selvi Gunel; Eser Sözmen
Source:
Journal of medicinal food 2019 v.22 no.11 pp. 1118-1126
ISSN:
1557-7600
Subject:
2,5-dihydroxybenzoic acid; Vaccinium myrtillus; antineoplastic activity; antineoplastic agents; antioxidant activity; antioxidants; apoptosis; blueberries; cytotoxicity; diet; flow cytometry; fruit extracts; kaempferol; liquid chromatography; neoplasms; oxidants; oxidative stress; polyphenols; protein composition; protein microarrays; proteins; quercetin; tandem mass spectrometry; therapeutics
Abstract:
... In recent years, natural products gained popularity with their anti-inflammatory and antioxidant effects mediated by chemical compounds within their composition. Study results offering them as palliative therapy options in cancer or as anticancer agents with high levels of cytotoxicity brought a new approach to combine cancer treatment protocols with these products. From a different perspective, e ...
DOI:
10.1089/jmf.2019.0098

36. Assessment of morphological and phytochemical attributes in triploid and hexaploid plants of the bioenergy crop Miscanthus×giganteus

Author:
Bimal Kumar Ghimire; Eun Soo Seong; Truong Xuan Nguyen; Ji Hye Yoo; Chang Yeon Yu; Seung Hyun Kim; Ill-Min Chung
Source:
Industrial crops and products 2016 v.89 pp. 231-243
ISSN:
0926-6690
Subject:
2,5-dihydroxybenzoic acid; C4 plants; Miscanthus; aluminum; biomass production; calcium; catechin; cellulose; chlorogenic acid; chromium; cobalt; colchicine; copper; energy; energy crops; grasses; hexaploidy; high performance liquid chromatography; iron; lead; leaf extracts; leaves; lignin; magnesium; manganese; myricetin; nickel; photosynthesis; potassium; pyrogallol; selenium; silicon; sodium; spectroscopy; strontium; sulfur; triploidy; warm season; zinc
Abstract:
... Giant Miscanthus (Miscanthus×giganteus) is a perennial, warm-season C4 grass. It is a sterile triploid that grows rapidly, accumulates significant biomass, and has the potential to be a new bioenergy crop. Hexaploid Miscanthus×giganteus can be induced from triploid M×giganteus using colchicine. Here, we compared a range of parameters between triploid and hexaploid plants using phytochemical and hi ...
DOI:
10.1016/j.indcrop.2016.04.051

37. Assessment of the bioactive phenolic composition of Acer truncatum seed coat as a byproduct of seed oil

Author:
Hang Fan; Liwei Sun; Lingguang Yang; Jinchi Zhou; Peipei Yin; Ke Li; Qiang Xue; Xiang Li; Yujun Liu
Source:
Industrial crops and products 2018 v.118 pp. 11-19
ISSN:
0926-6690
Subject:
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; Acer truncatum; acetone; antioxidant activity; antioxidants; byproducts; epicatechin; ethanol; manufacturing; naringenin; proanthocyanidins; procyanidins; seed coat; seed oils; tannins; wastes
Abstract:
... Acer truncatum seed coat is generally abandoned as waste during the process of manufacturing seed oil due to a lack of knowledge of the phytochemical composition of this byproduct. It is well known that brown-colored seed coat is rich in polyphenols; therefore, we investigated the bioactive phenolic composition of A. truncatum seed coat in this study. To obtain an extract containing most bioactive ...
DOI:
10.1016/j.indcrop.2018.03.030

38. Automated Dispersive Solid-Phase Extraction Using Dissolvable Fe3O4-Layered Double Hydroxide Core–Shell Microspheres as Sorbent

Author:
Tang Sheng; Chia Guo Hui; Chang Yuepeng; Lee Hian Kee
Source:
Analytical chemistry 2014 v.86 no.22 pp. 11070-11076
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; agitation; aspirin; automation; centrifugation; detection limit; high performance liquid chromatography; pH; personal care products; sewage; solid phase extraction; statistical analysis; temperature
Abstract:
... Automation of dispersive solid-phase extraction (d-SPE) presents significant challenges. Separation of the sorbent from the spent sample cannot be conducted without manual operations, including centrifugation, a widely used means of isolating a solid material from solution. In this work, we report an approach to d-SPE using dissolvable magnetic Fe₃O₄-layered double hydroxide core–shell microsphere ...
DOI:
10.1021/ac503323e

39. Automated normal phase nano high performance liquid chromatography/matrix assisted laser desorption/ionization mass spectrometry for analysis of neutral and acidic glycosphingolipids

Author:
Zarei, Mostafa; Kirsch, Stephan; Müthing, Johannes; Bindila, Laura; Peter-Katalinić, Jasna
Source:
Analytical and bioanalytical chemistry 2008 v.391 no.1 pp. 289-297
ISSN:
1618-2642
Subject:
2,5-dihydroxybenzoic acid; cations; crystallization; desorption; erythrocytes; glycosphingolipids; high performance liquid chromatography; humans; ionization; lithium; mass spectrometry; mice; screening; solvents
Abstract:
... The coupling of nano high-performance liquid chromatography (nanoHPLC) with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) via an automatic spotting roboter was developed and adapted for the first time for the analysis of complex mixtures of glycosphingolipids (GSLs). The 2,5-dihydroxybenzoic acid and 6-azo-2-thiothymine matrix systems were adjusted to concurrently meet ...
DOI:
10.1007/s00216-008-1932-0
PubMed:
18327675

40. Banana plant as a source of valuable antimicrobial compounds and its current applications in the food sector

Author:
Heba Sayed Mostafa
Source:
Journal of food science 2021 v.86 no.9 pp. 3778-3797
ISSN:
0022-1147
Subject:
2,5-dihydroxybenzoic acid; Musa; anti-infective agents; antioxidants; bananas; beverages; bio-packaging; biopreservatives; carene; cultivars; dopamine; ferulic acid; food industry; food storage; fruits; lupeol; meat; perishable foods; prebiotics; sucrose; value added; wastes; wheat
Abstract:
... Bananas (Musaceae) are one of the world's most common fruit crops and the oldest medicinal plants that are used to treat a variety of infections. There has been recent interest in elucidating the efficiency of the naturally active ingredients, particularly the antimicrobials, in this plant. This review begins with a short background of the banana plant and its cultivars as well as a brief descript ...
DOI:
10.1111/1750-3841.15854

41. Bioaccessibility and antioxidant activity of phenolic compounds in frozen pulps of Brazilian exotic fruits exposed to simulated gastrointestinal conditions

Author:
Rodrigo Luiz Targino Dutra; Aline Macedo Dantas; Débora de Araújo Marques; Jéssica Dayanne Ferreira Batista; Bruno Raniere Lins de Albuquerque Meireles; Ângela Maria Tribuzy de Magalhães Cordeiro; Marciane Magnani; Graciele da Silva Campelo Borges
Source:
Food research international 2017 v.100 pp. 650-657
ISSN:
0963-9969
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; bioavailability; gallic acid; gastrointestinal system; introduced plants; iron; pulp
Abstract:
... This study characterized the phenolic profile in siriguela, umbu-cajá and mangaba, as well in their frozen pulps (FPs). The bioaccessibility of phenolic compounds and the antioxidant activity of the FP dialysates were determined following exposure to simulated gastrointestinal conditions. The profile of phenolic compounds identified in fruit and FPs were relatively similar. After pulp processing, ...
DOI:
10.1016/j.foodres.2017.07.047

42. Bioactivities and phenolic constituents relationship of Muğla thyme and pine honey of Turkey with the chemometric approach

Author:
Yusuf Sıcak; Ayşe Şahin-Yağlıoğlu; Mehmet Öztürk
Source:
Journal of food measurement & characterization 2021 v.15 no.4 pp. 3694-3707
ISSN:
2193-4126
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; alpha-tocopherol; anti-inflammatory activity; antioxidant activity; antioxidants; brain; breasts; butylated hydroxytoluene; chemometrics; chlorogenic acid; cholinesterase; cinnamic acid; colon; ethyl acetate; fluorouracil; fumaric acid; honey; measurement; neoplasm cells; odors; protocatechuic acid; salicylic acid; syringic acid; taste; therapeutics; thyme; urease; vanillic acid
Abstract:
... The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro antiproliferative, antioxidant, anticholinesterase, anti-inflammatory, tyrosinase inhibitory, and urease inhibitory activities were used to investigate the therapeutic potentials. The an ...
DOI:
10.1007/s11694-021-00940-8

43. Biodegradation Mechanism of Phenanthrene by Halophilic Hortaea sp. B15

Author:
Risky Ayu Kristanti; Tony Hadibarata; Dunia A. Al Farraj; Mohamed Soliman Elshikh; Roua M. Alkufeidy
Source:
Water, air, and soil pollution 2018 v.229 no.10 pp. 324
ISSN:
0049-6979
Subject:
2,5-dihydroxybenzoic acid; bacteria; biodegradation; bioremediation; fungi; liquids; phenanthrenes; polluted soils; quinones; salicylic acid; salinity; spectral analysis; spectrophotometers
Abstract:
... This aim of the study is to investigate a halophilic bacterium Hortaea sp. B15, isolated from petroleum-contaminated soil for biodegradation of phenanthrene. Hortaea sp. B15 has the ability to completely degrade phenanthrene (100 mg/L) under salinity 10% within 1-week incubation. The metabolitic product of phenanthrene was identified and assayed by using ultraviolet-visible spectrophotometer and m ...
DOI:
10.1007/s11270-018-3969-9

44. Biodegradation of p-Cresol by Bacillus sp. Strain PHN 1

Author:
Tallur, P. N.; Megadi, V. B.; Kamanavalli, C. M.; Ninnekar, H. Z.
Source:
Current microbiology 2006 v.53 no.6 pp. 529-533
ISSN:
0343-8651
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Bacillus (bacteria); bacteria; biodegradation; bioremediation; carbon; energy; enzyme activity; o-cresol; p-cresol; phenol; soil
Abstract:
... A bacterium capable of utilizing p-cresol as sole source of carbon and energy was isolated from soil and identified as a Bacillus species. The organism also utilized phenol, o-cresol, m-cresol, 4-hydroxybenzoic acid, and gentisic acid as growth substrates. The organism degraded p-cresol to 4-hydroxybenzoic acid, which was further metabolized by a gentisate pathway, as evidenced by isolation and id ...
DOI:
10.1007/s00284-006-0309-x
PubMed:
17106800

45. Biotransformation of indole by Cupriavidus sp. strain KK10 proceeds through N-heterocyclic- and carbocyclic-aromatic ring cleavage and production of indigoids

Author:
Kimiko Fukuoka; Keita Tanaka; Yasuhiro Ozeki; Robert A. Kanaly
Source:
International Biodeterioration & Biodegradation 2015 v.97 pp. 13-24
ISSN:
0964-8305
Subject:
2,5-dihydroxybenzoic acid; Cupriavidus; biobased products; biotransformation; electrospray ionization mass spectrometry; genes; indigo; liquid chromatography; oxidation; phylogeny; pollutants; ribosomal RNA; soil bacteria
Abstract:
... Comprehensive analyses of the biotransformation of the N-heteroaromatic environmental pollutant, indole, by a newly isolated soil bacterium designated strain KK10, were conducted by liquid chromatography negative electrospray ionization tandem mass spectrometry (LC/ESI(−)–MS/MS). Numerous indole bioproducts were revealed and provided evidence for multiple pathways of indole biotransformation by th ...
DOI:
10.1016/j.ibiod.2014.11.007

46. Bithiophenic MALDI matrices as valuable leads for the selective detection of alkaloids

Author:
Ali Jaber; Denis Seraphin; David Guilet; Junichi Osuga; Edmond Cheble; Ghassan Ibrahim; Pascal Richomme; Andreas Schinkovitz
Source:
Analytical and bioanalytical chemistry 2017 v.409 no.29 pp. 6791-6801
ISSN:
1618-2642
Subject:
2,5-dihydroxybenzoic acid; Atropa belladonna; Colchicum autumnale; Senecio vulgaris; detection limit; dietary supplements; flavonoids; humans; liquid chromatography; mass spectrometry; peptides; quality control; sparteine; steroids
Abstract:
... Alkaloids represent a group of biologically most interesting compounds commonly used in modern medicines but also known for exhibiting severe toxic effects. Therefore, the detection of alkaloids is an important issue in quality control of plants, dietary supplements, and herbal pharmaceutical and mostly facilitated by methods such as GC or LC-MS. However, benefitting from the development of select ...
DOI:
10.1007/s00216-017-0634-x

47. Bound phenolic compounds and antioxidant properties of whole grain and bran of white, red and black rice

Author:
Yuehan Pang; Sulaiman Ahmed; Yanjie Xu; Trust Beta; Zhiwei Zhu; Yafang Shao; Jinsong Bao
Source:
Food chemistry 2018 v.240 pp. 212-221
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; black rice; bran; color; ferulic acid; gallic acid; p-coumaric acid; phytopharmaceuticals; protocatechuic acid; sinapic acid; vanillic acid; whole grain foods
Abstract:
... Total phenolic content (TPC), individual phenolic acid and antioxidant capacity of whole grain and bran fraction 18 rices with different bran color were investigated. The levels of TPC in bound fractions were significantly higher than those in the free fractions either in the whole grains or brans. The main bound phenolic acids in white rice samples were ferulic acid, p-coumaric acid, and isoferul ...
DOI:
10.1016/j.foodchem.2017.07.095

48. Carbohydrates, volatile and phenolic compounds composition, and antioxidant activity of calabura (Muntingia calabura L.) fruit

Author:
Gustavo Araujo Pereira; Henrique Silvano Arruda; Damila Rodrigues de Morais; Marcos Nogueira Eberlin; Glaucia Maria Pastore
Source:
Food research international 2018 v.108 pp. 264-273
ISSN:
0963-9969
Subject:
2,5-dihydroxybenzoic acid; Muntingia calabura; antioxidant activity; bioactive compounds; caffeic acid; catechin; color; energy; epigallocatechin; esterification; flavor; food industry; fructose; fruits; functional foods; gallic acid; gas chromatography-mass spectrometry; glucose; glycosylation; naringenin; polyols; protocatechuic acid; quercetin; solid phase microextraction; tandem mass spectrometry; terpenoids; volatile compounds
Abstract:
... Soluble carbohydrates, volatile and phenolic compounds from calabura fruit as well as its antioxidant activity were assessed. The low amount of fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) and similar amount of glucose and fructose allow us to classify the calabura berry as low-FODMAPs. The terpenes β-Farnesene and dendrolasin identified by SPME-GC-MS were the major volatile ...
DOI:
10.1016/j.foodres.2018.03.046

49. Cardiovascular protection effect of a Northeastern Brazilian lyophilized red wine in spontaneously hypertensive rats

Author:
Natália T.M. Calzerra; Mayara P. Melo; Pablo F. Santos; Kívia S. Assis; Priscilla M.P. Maciel; Renata L.P. Vieira; Fátima de L.A.A. Azevedo; Angela M.T.M. Cordeiro; Bruno R.L.A. Meireles; Islania G.A. Araújo; Robson C. Veras; Isac A. Medeiros
Source:
Journal of functional foods 2022 v.88 pp. 104868
ISSN:
1756-4646
Subject:
2,5-dihydroxybenzoic acid; blood pressure; cardioprotective effect; cardiovascular system; catechin; collagen; freeze drying; high performance liquid chromatography; oxidative stress; red wines; resveratrol; Brazil
Abstract:
... Moderate consumption of wine has a protective effect on the cardiovascular system. This study proposes to investigate the cardiovascular protective effect of the lyophilized red wine RIO SOL Cabernet-Sauvignon (LRW-RSCS), produced in Northeastern Brazil, in SHR. Sixteen different phenolic compounds, such as gentisic acid, catechin, and resveratrol were identified in LRW-RSCS using high-performance ...
DOI:
10.1016/j.jff.2021.104868

50. Characterization and application of Croton blanchetianus Baill extract for lamb ribs preservation

Author:
Maria José de Figueiredo; Cristiani Viegas Brandão Grisi; Ângela Maria Santiago; Erica de Andrade Vieira; Angela Maria Tribuzy de Magalhães Cordeiro; Anderson Ferreira Vilela; Arianne Dantas Viana; Solange de Sousa; Líbia de Sousa Conrado
Source:
Food chemistry 2022 v.373 pp. 131404
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Artemia salina; Aspergillus flavus; Croton; Escherichia coli; Listeria innocua; Salmonella enterica; Staphylococcus aureus; absorbents; antimicrobial properties; antioxidant activity; antioxidants; catechin; cold storage; food chemistry; heat treatment; leaf extracts; lethal dose 50; lipid peroxidation; myricetin; ovens; rosmarinic acid
Abstract:
... This research evaluated the antioxidant, antimicrobial and toxicity potential of the leaf extract of Croton blanchetianus Baill (ExCb) and its effect on the conservation of lamb ribs. The ExCb (control treatment) revealed higher concentration of 2,5-dihydroxybenzoic acid (190.10 mg/g), catechin (84.10 mg/g), rosmarinic acid (56.01 mg/g), 4-hydroxybenzoic acid (52.05 mg/g) and myricetin (40.00 mg/g ...
DOI:
10.1016/j.foodchem.2021.131404