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You searched for: Subject 2,5-dihydroxybenzoic acid Remove constraint Subject: 2,5-dihydroxybenzoic acid
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1. Antioxidant capacity and interaction of endogenous phenolic compounds from tea seed oil

Author:
Guoyan Liu; Wenqi Zhu; Sitong Li; Wanli Zhou; Huijuan Zhang; Jing Wang; Xiaofang Liu; Jixian Zhang; Li Liang; Xin Xu
Source:
Food chemistry 2022 v.376 pp. 131940
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; antioxidants; ethanol; food chemistry; lipid peroxidation; oxidative stability; quercetin; rancidity; seed oils; tartaric acid
Abstract:
... Endogenous phenols play a significant role in delaying oil rancidity. In this study, the profile of 22 endogenous phenols was determined from tea seed oil by UPLC-MS/MS, of which 15 phenols were identified for the first time. Then seven phenols with high content and strong antioxidant capacity were selected to investigate interaction using the DPPH· and Rancimat. It was found that the interaction ...
DOI:
10.1016/j.foodchem.2021.131940

2. Cardiovascular protection effect of a Northeastern Brazilian lyophilized red wine in spontaneously hypertensive rats

Author:
Natália T.M. Calzerra; Mayara P. Melo; Pablo F. Santos; Kívia S. Assis; Priscilla M.P. Maciel; Renata L.P. Vieira; Fátima de L.A.A. Azevedo; Angela M.T.M. Cordeiro; Bruno R.L.A. Meireles; Islania G.A. Araújo; Robson C. Veras; Isac A. Medeiros
Source:
Journal of functional foods 2022 v.88 pp. 104868
ISSN:
1756-4646
Subject:
2,5-dihydroxybenzoic acid; blood pressure; cardioprotective effect; cardiovascular system; catechin; collagen; freeze drying; high performance liquid chromatography; oxidative stress; red wines; resveratrol; Brazil
Abstract:
... Moderate consumption of wine has a protective effect on the cardiovascular system. This study proposes to investigate the cardiovascular protective effect of the lyophilized red wine RIO SOL Cabernet-Sauvignon (LRW-RSCS), produced in Northeastern Brazil, in SHR. Sixteen different phenolic compounds, such as gentisic acid, catechin, and resveratrol were identified in LRW-RSCS using high-performance ...
DOI:
10.1016/j.jff.2021.104868

3. Characterization and application of Croton blanchetianus Baill extract for lamb ribs preservation

Author:
Maria José de Figueiredo; Cristiani Viegas Brandão Grisi; Ângela Maria Santiago; Erica de Andrade Vieira; Angela Maria Tribuzy de Magalhães Cordeiro; Anderson Ferreira Vilela; Arianne Dantas Viana; Solange de Sousa; Líbia de Sousa Conrado
Source:
Food chemistry 2022 v.373 pp. 131404
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Artemia salina; Aspergillus flavus; Croton; Escherichia coli; Listeria innocua; Salmonella enterica; Staphylococcus aureus; absorbents; antimicrobial properties; antioxidant activity; antioxidants; catechin; cold storage; food chemistry; heat treatment; leaf extracts; lethal dose 50; lipid peroxidation; myricetin; ovens; rosmarinic acid
Abstract:
... This research evaluated the antioxidant, antimicrobial and toxicity potential of the leaf extract of Croton blanchetianus Baill (ExCb) and its effect on the conservation of lamb ribs. The ExCb (control treatment) revealed higher concentration of 2,5-dihydroxybenzoic acid (190.10 mg/g), catechin (84.10 mg/g), rosmarinic acid (56.01 mg/g), 4-hydroxybenzoic acid (52.05 mg/g) and myricetin (40.00 mg/g ...
DOI:
10.1016/j.foodchem.2021.131404

4. Comparative assessment of phenolics, antioxidant and antiproliferative activities between Hippophae rhamnoides ssp. sinensis and H. tibetana leaf in Qinghai-Tibet Plateau

Author:
Juan Wei; Tingting Su; Hailan Su; Yumei Jiang; Jixin Li; Yang Bi
Source:
Food bioscience 2022 v.46 pp. 101507
ISSN:
2212-4292
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Hippophae rhamnoides; antioxidant activity; benzoic acid; chlorides; cyanidin; ellagic acid; epigallocatechin; ethanol; flavanols; flavanones; free radicals; healthy diet; leaves; methyl gallate; myrtillin; procyanidins; rutin; taxifolin; China
Abstract:
... Hippophae rhamnoides ssp. sinensis (Rha) and H. tibetana (Tib) are two species of sea buckthorn which distribute in Qinghai-Tibet Plateau. Our results showed that both sea buckthorn leaf exhibited high total phenolic and flavonoid content, and Rha leaf showed much higher level. In addition, 66 phenolic compounds were detected, belonging to classes of benzoic acid derivatives, flavonols, flavanols, ...
DOI:
10.1016/j.fbio.2021.101507

5. Dual-polarity MALDI mass spectrometry and imaging of oil binders and fatty acids in artworks using cyanographene as a single matrix

Author:
Tanushree Dutta; Tomáš Steklý; Lukáš Kučera; Karel Lemr
Source:
Talanta 2022 v.242 pp. 123291
ISSN:
0039-9140
Subject:
2,5-dihydroxybenzoic acid; energy transfer; fatty acids; graphene; ionization; matrix-assisted laser desorption-ionization mass spectrometry; oils; oxidation; triacylglycerols
Abstract:
... Matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) and imaging mass spectrometry (IMS) are being increasingly recognized for the detection and visualization of various organic species including lipids and fatty acids. Nevertheless, most MALDI matrices perform optimally in one ionization mode. This study investigates the performance of cyano derivative of graphene (G-CN) as a ...
DOI:
10.1016/j.talanta.2022.123291

6. Modification of β-lactoglobulin by phenolic conjugations: Protein structural changes and physicochemical stabilities of stripped hemp oil-in-water emulsions stabilized by the conjugates

Author:
Hui Li; Yanxiong Pan; Zhongyu Yang; Jiajia Rao; Bingcan Chen
Source:
Food hydrocolloids 2022 v.128 pp. 107578
ISSN:
0268-005X
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; antioxidants; biopolymers; emulsifiers; emulsifying; emulsions; hemp; hydrocolloids; hydrophobicity; lipid peroxidation; oil-water interface; oxidative stability; solubility; surface tension
Abstract:
... Preventing lipid oxidation at the oil-water interface is critical for suppressing food emulsion deterioration and thus minimizing the economy loss. However, it is challenging to specifically localize the needed antioxidant species at the interface, failing in which often results in poor oxidative stability of emulsions. Here, we show that by grafting gentisic acid (GA) on β-lactoglobulin (βLG) at ...
DOI:
10.1016/j.foodhyd.2022.107578

7. Natural Deep Eutectic Solvents Based on Choline Chloride and Phenolic Compounds as Efficient Bioadhesives and Corrosion Protectors

Author:
Matías L. Picchio; Daniela Minudri; Daniele Mantione; Miryam Criado-Gonzalez; Gregorio Guzmán-González; Ruth Schmarsow; Alejandro J. Müller; Liliana C. Tomé; Roque J. Minari; David Mecerreyes
Source:
ACS sustainable chemistry & engineering 2022 v.10 no.25 pp. 8135-8142
ISSN:
2168-0485
Subject:
2,5-dihydroxybenzoic acid; ambient temperature; bioadhesives; choline; choline chloride; corrosion; gelatin; green chemistry; liquids; polyphenols; pyrogallol; solvation; steel; therapeutics; thermal stability; viscoelasticity
Abstract:
... Natural deep eutectics solvents (NADES), owing to their high solvation capacity and nontoxicity, are actively being sought for many technological applications. Herein, we report a series of novel NADES based on choline chloride and plant-derived polyphenols. Most of the obtained phenolic NADES have a wide liquid range and high thermal stability above 150 °C. Among them, small-sized polyphenols, li ...
DOI:
10.1021/acssuschemeng.2c01976

8. Natural aldose reductase inhibitors for treatment and prevention of diabetic cataract: A review

Author:
Nour Elhouda Daoudi; Omar Bouziane; Mohamed Bouhrim; Mohamed Bnouham
Source:
Herba Polonica 2022 v.68 no.1 pp. 35-58
ISSN:
2449-8343
Subject:
2,5-dihydroxybenzoic acid; aldehyde reductase; andrographolide; apigenin; cataract; delphinidin; gallic acid; glucose; luteolin; p-coumaric acid; propionic acid; protocatechuic acid; quercetin; sorbitol; syringic acid; therapeutics
Abstract:
... Introduction: Aldose reductase (AR) is an enzyme that catalyzes the reduction of glucose to sorbitol responsible for the development of diabetic complications like cataracts. Medicinal plants contain several phytocompounds that can inhibit this enzyme. Objective: The purpose of this review is to cite medicinal plants that have been tested for their ability to inhibit aldose reductase and consequen ...
DOI:
10.2478/hepo-2022-0002

9. Profiling of Phenolic Compounds in Fruit Pericarp of Zanthoxylum rhetsa (Roxb.) DC

Author:
Gourish R. Karanjalker; Avni G. Karanjalker; Ajit A. Waman
Source:
National Academy science letters 2022 v.45 no.4 pp. 307-310
ISSN:
0250-541X
Subject:
2,5-dihydroxybenzoic acid; Zanthoxylum rhetsa; caffeic acid; edible fruits; ferulic acid; flavor; p-coumaric acid; pericarp; shelf life; sinapic acid; spices; India
Abstract:
... Indian prickly ash [Zanthoxylum rhetsa (Roxb.) DC.] is a multipurpose, but lesser known underutilized spice of Western Ghats of India. The edible fruit pericarp is commonly used in culinary items in dried form to improve flavor and shelf life of culinary products especially fish curries. In the present study, we have identified 18 phenolic acids from Zanthoxyllum rhetsa fruit pericarp using LC–MS/ ...
DOI:
10.1007/s40009-022-01134-6

10. The hydroperoxyl radical scavenging activity of natural hydroxybenzoic acids in oil and aqueous environments: Insights into the mechanism and kinetics

Author:
Do Thi Ngoc Hang; Nguyen Thi Hoa; Huynh Ngoc Bich; Adam Mechler; Quan V. Vo
Source:
Phytochemistry 2022 v.201 pp. 113281
ISSN:
0031-9422
Subject:
2,5-dihydroxybenzoic acid; antioxidants; density functional theory; electron transfer; hydroxybenzoic acids; oils; onions; pH; plant biochemistry; potato peels; radishes
Abstract:
... Foods that contain hydroxybenzoic acid derivatives (HBA) include red fruits, black radish, onion, and potato peel. HBA are widely known for their anti-inflammatory, anti-cancer, and especially antioxidant capabilities; however, a comprehensive study of the mechanism and kinetics of the antiradical action of these compounds has not been performed. Here, we report a study on the mechanisms and kinet ...
DOI:
10.1016/j.phytochem.2022.113281

11. A new dibenzofuran derivative from the stem bark of Scyphocephalium ochocoa with anti-inflammatory and cytotoxic activities

Author:
Guy Raymond Feuya Tchouya; Hibrahim Foundikou; Marius Mbiantcha; Jean Jules Bankeu Kezetas; Jean-Bernard Bongui; Jean Claude Tchouankeu; Jacques Lebibi; Dattatraya H. Dethe
Source:
Natural product research 2022 v.36 no.6 pp. 1503-1514
ISSN:
1478-6427
Subject:
2,5-dihydroxybenzoic acid; anti-inflammatory activity; bark; chemiluminescence; cytotoxicity; dibenzofuran; drug therapy; epicatechin; methanol; methylene chloride; myo-inositol; research; spectral analysis; toxicity testing
Abstract:
... The phytochemical investigation of the dichloromethane/methanol (1:1) extract of the stem bark of Scyphocephalium ochocoa, led to the isolation of one new dibenzofuran derivative, named scyphocephalione A (1), along with three other compounds, including epicatechin (2), gentisic acid (3) and myo-inositol (4). The structures of all the compounds were established with help of spectroscopic data incl ...
DOI:
10.1080/14786419.2021.1894561

12. Analysis of phytochemical composition of leaf extract of sacred fig (Ficus religiosa L.) by UPLC-QqQ-MS and assessment of their hepatocurative potential in mouse model

Author:
Udhayaraj Suriyakalaa; Devanesan Arul Ananth; Rajamanickam Ramachandran; Devaraj Sankarganesh; Jayaraman Angayarkanni; Zipora Tietel; Shanmugam Achiraman
Source:
South African journal of botany 2022 pp. -
ISSN:
0254-6299
Subject:
2,5-dihydroxybenzoic acid; Ficus religiosa; antioxidant activity; bilirubin; carbon tetrachloride; catechin; chemical constituents of plants; creatinine; ethnobotany; figs; hepatotoxicity; histopathology; leaf extracts; leaves; liver; mass spectrometry; mice; polyphenols; protocatechuic acid; quinic acid; rutin; ultra-performance liquid chromatography; urea
Abstract:
... In view of their remarkable pharmacological properties and bioactivities Ficus sp. are used in traditional medicines. Ficus religiosa is richly endowed with ethnobotanical values and it is a promising entity in various medicinal formulations; however, comprehensive phytochemical identification and quantification of F. religiosa using Ultra Performance Liquid Chromatography Triple Quadrupole Mass S ...
DOI:
10.1016/j.sajb.2022.01.007

13. Anti-influenza mechanism of phenolic phytochemicals from Canarium album (Lour.) DC. leaf extract

Author:
Mengjie Xiao; Bobby Lim-Ho Kong; Yahui Zhang; Yinhua Yang; Jiaqi Lu; Hung-Kay Lee; Fei Cao; Pang-Chui Shaw
Source:
Journal of ethnopharmacology 2022 v.292 pp. 115175
ISSN:
0378-8741
Subject:
2,5-dihydroxybenzoic acid; Canarium album; Influenza A virus; circular dichroism spectroscopy; flavonoids; glycosides; heat; hemagglutination; hemagglutinins; influenza; leaf extracts; leaves; lungs; moieties; phenotype; probability; reverse genetics; sialidase; toxic substances; traditional medicine; viruses
Abstract:
... Canarium album (Lour.) DC. belongs to the Burseraceae family. Its leaf, named as Ganlanye (GLY), was recorded to treat warm disease symptoms via clearing lung heat and toxicants in medical classics. Its aqueous extract had anti-influenza activity in our previous phenotypic screening. However, its active components and mechanism were not identified. We aim to isolate the anti-influenza phytochemica ...
DOI:
10.1016/j.jep.2022.115175

14. Chemically heterogeneous carbon dots enhanced cholesterol detection by MALDI TOF mass spectrometry

Author:
Dominika Houdová; Juan Soto; Rita Castro; João Rodrigues; Mª Soledad Pino-González; Marijana Petković; Teresa J Bandosz; Manuel Algarra
Source:
Journal of colloid and interface science 2021 v.591 pp. 373-383
ISSN:
0021-9797
Subject:
2,5-dihydroxybenzoic acid; Gibbs free energy; cholesterol; desorption; ionization; matrix-assisted laser desorption-ionization mass spectrometry; models
Abstract:
... A binary system composed of carbon dots (CDs) and N-doped CDs (N-CDs) embedded in an organic matrix was used for the analysis of cholesterol by MALDI (matrix-assisted laser desorption and ionization time-of-flight) mass spectrometry, as a model for detection of small, biologically relevant molecules. The results showed that both CDs are sensitive to the cholesterol and can be used either alone or ...
DOI:
10.1016/j.jcis.2021.02.004

15. Daily consumption of cranberry improves endothelial function in healthy adults: a double blind randomized controlled trial

Author:
Christian Heiss; Geoffrey Istas; Rodrigo P. Feliciano; Timon Weber; Brian Wang; Claudia Favari; Pedro Mena; Daniele Del Rio; Ana Rodriguez-Mateos
Source:
Food & function 2022 v.13 no.7 pp. 3812-3824
ISSN:
2042-650X
Subject:
2,5-dihydroxybenzoic acid; Internet; blood glucose; blood pressure; cranberries; glucose; heart rate; males; metabolites; propionic acid; regression analysis; urine
Abstract:
... Background: Previous studies indicate cardiovascular health benefits of cranberry juice consumption. However, whether daily consumption of whole cranberries will have sustained vascular benefits in healthy individuals is currently unknown. Objective: To investigate the vascular effects of acute and daily consumption of freeze dried whole cranberry in healthy men and how effects relate to circulati ...
DOI:
10.1039/d2fo00080f

16. Design, synthesis and characterization of lysozyme–gentisic acid dual-functional conjugates with antibacterial/antioxidant activities

Author:
Hui Li; Yanxiong Pan; Chun Li; Zhongyu Yang; Jiajia Rao; Bingcan Chen
Source:
Food chemistry 2022 v.370 pp. 131032
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; antioxidants; chemical bonding; food chemistry; food industry; food waste; functional foods; lipid peroxidation; lysozyme; particle size
Abstract:
... Both microbiological and chemical food spoilages remain to be the major challenges in the food industry's efforts to combat food waste and loss because of the lack of high efficacy food preservatives. In this study, dual-functional conjugates that simultaneously suppress both lipid oxidation and microorganism growth are fabricated by covalently conjugating natural antioxidant gentisic acid (GA) on ...
DOI:
10.1016/j.foodchem.2021.131032

17. Determination of Chemical Constituents and Antioxidant Activities of Leaves and Stems from Jatropha cinerea (Ortega) Müll. Arg and Jatropha cordata (Ortega) Müll. Arg

Author:
Yeimi Cecilia Vega-Ruiz; Corina Hayano-Kanashiro; Nohemí Gámez-Meza; Luis Angel Medina-Juárez
Source:
Plants 2021 v.10 no.2 pp. -
ISSN:
2223-7747
Subject:
2,5-dihydroxybenzoic acid; Jatropha cordata; antioxidant activity; antioxidants; catechol; flavonoids; gallic acid; leaves; sap; secondary metabolites; traditional medicine; weather; Mexico
Abstract:
... Jatropha species have been shown to be an important source of secondary metabolites with different biological effects. Jatropha cinerea (Ortega) Müll. Arg and Jatropha cordata (Ortega) Müll. Arg are distributed in the Northwestern region of Mexico, are adapted to extreme weather conditions and are widely used (stems, leaves, and sap) in traditional medicine. The aim of the present study was to car ...
DOI:
10.3390/plants10020212

18. Disruption of the primary salicylic acid hydroxylases in rice enhances broad‐spectrum resistance against pathogens

Author:
Yanjun Zhang; Qilu Yu; Shilei Gao; Ningning Yu; Li Zhao; Jinbin Wang; Jiangzhe Zhao; Peng Huang; Linbo Yao; Mo Wang; Kewei Zhang
Source:
Plant, cell and environment 2022 v.45 no.7 pp. 2211-2225
ISSN:
0140-7791
Subject:
2,5-dihydroxybenzoic acid; Magnaporthe oryzae; Oryza sativa; Xanthomonas oryzae pv. oryzae; callose; environment; paddies; panicles; reactive oxygen species; rice; salicylic acid
Abstract:
... Salicylic acid (SA) is a crucial hormone involved in plant immunity. Rice (Oryza sativa) maintains high SA levels that are not induced by pathogens. However, the roles of SA in rice immunity and yield remain largely unknown. Here, we identified SA 5‐hydroxylases 1 (OsS5H1) and 2 (OsS5H2) as the primary enzymes engaged in catalysing SA to 2,5‐dihydroxybenzoic acid (2,5‐DHBA) in rice. SA levels were ...
DOI:
10.1111/pce.14328

19. Do drought-adapted peanut genotypes have different bioactive compounds and ROS-scavenging activity?

Author:
Fernanda Francetto Juliano; Adna Prado Massarioli; Rosa Maria Lamuela-Raventos; José Fernando Rinaldi de Alvarenga; Liziane Maria de Lima; Roseane Cavalcanti dos Santos; Camila Furtunato da Silva; Severino Matias de Alencar
Source:
European food research & technology 2021 v.247 no.6 pp. 1369-1378
ISSN:
1438-2377
Subject:
2,5-dihydroxybenzoic acid; drought tolerance; fatty acid composition; food research; genotype; peanuts; polyphenols; technology; tocopherols; Senegal
Abstract:
... Peanuts are grown in both developed and developing countries, and their cultivation has been considerably expanded to semiarid and arid regions. In this study, we investigated the ROS-scavenging activity and bioactive composition of hydric stress-tolerant (BR1, Senegal 55,437, L7 Bege, F.M424B) and -susceptible peanut genotypes (LViPE-06, LGoPE-06 and Tatu). Peanut grains were examined for their f ...
DOI:
10.1007/s00217-021-03714-0

20. Evaluation and optimization of the influence of silver cluster ions on the MALDI-TOF-MS analysis of polystyrene nanoplastic polymers

Author:
Théogène Habumugisha; Zixing Zhang; Jean Claude Ndayishimiye; François Nkinahamira; Alexis Kayiranga; Eric Cyubahiro; Abdul Rehman; Changzhou Yan; Xian Zhang
Source:
Analytical methods 2022 v.14 no.7 pp. 763-772
ISSN:
1759-9679
Subject:
2,5-dihydroxybenzoic acid; anthracenes; benzoic acid; cationization; chlorides; desorption; nanoplastics; polystyrenes; silver; silver nitrate; sinapic acid
Abstract:
... In the analysis of polystyrene nanoplastics (PSNs), a nonpolar polymer (NP), using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), silver salts were used as cationization reagents and simultaneously brought the potential problems of silver clusters that interfered with the PSN signal of MS. To detect PSNs, silver trifluoroacetate (AgTFA) and silver nitr ...
DOI:
10.1039/d1ay02219a

21. Evaluation of antioxidant supplementation in must on the development and potential reduction of different compounds involved in atypical ageing of wine using HPLC-HRMS

Author:
Tiziana Nardin; Tomas Roman; Susanne Dekker; Giorgio Nicolini; Francesco Thei; Barbara Masina; Roberto Larcher
Source:
Lebensmittel-Wissenschaft + Technologie 2022 v.154 pp. 112639
ISSN:
0023-6438
Subject:
2,5-dihydroxybenzoic acid; adjuvants; analysis of covariance; antioxidants; ascorbic acid; ellagic acid; fermentation; gallic acid; glutathione; grapes; mass spectrometry; metabolites; models; off flavors
Abstract:
... Atypical aging of white wines (ATA) is an off-flavour characterised by rapid loss of fruity aromas and the development of unpleasant odours. This study aims to evaluate the effectiveness of different oenological adjuvants (4-ethylcatechol, 4-methylcatechol, gentisic acid, hydroxytyrosol, ascorbic acid, glutathione, ellagic acid, gallic acid, galla tannin, ellagic tannin, quebracho, grape tannins) ...
DOI:
10.1016/j.lwt.2021.112639

22. Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue

Author:
Xue Han; Jielong Guo; Yunxiao Gao; Jicheng Zhan; Yilin You; Weidong Huang
Source:
Food & function 2021 v.12 no.3 pp. 1262-1270
ISSN:
2042-650X
Subject:
2,5-dihydroxybenzoic acid; Chiroptera; anti-obesity effects; antioxidants; beta oxidation; brown adipocytes; brown adipose tissue; energy expenditure; energy intake; energy metabolism; heat production; high fructose diet; insulin resistance; lipids; obesity; oxidation; weight
Abstract:
... Since obesity occurs when energy intake is higher than energy expenditure, increasing energy expenditure is an effective strategy to prevent or treat obesity. Brown adipose tissue (BAT) is a classic energy-consuming organ whose thermogenesis function can be activated by dietary components. Gentisic acid (2,5-dihydroxybenzoic acid, (DHB)) is widely found in food and exhibits many physiological func ...
DOI:
10.1039/d0fo02474k

23. Hydralazine as a Versatile and Universal Matrix for High-Molecular Coverage and Dual-Polarity Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Author:
Weiwei Tang; Andrew Gordon; Fang Wang; Yanwen Chen; Bin Li
Source:
Analytical chemistry 2021 v.93 no.26 pp. 9083-9093
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; absorptivity; ammonia; analytical chemistry; desorption; kidneys; liver; metabolites; solvents; wavelengths
Abstract:
... Few matrices have the potential to be universally applicable for imaging vast endogenous compounds ranging from micro to macromolecules. In this article, we present hydralazine (HZN) as a versatile and universal matrix for matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) of a wide range of endogenous compounds between 50.0 and 20,000.0 Da. HZN was prepared from its ...
DOI:
10.1021/acs.analchem.1c00498

24. Impact of tomato pomace powder added to extruded snacks on the in vitro gastrointestinal behaviour and stability of bioactive compounds

Author:
Sibel Yagci; Rukiye Calıskan; Zeynep Saliha Gunes; Esra Capanoglu; Merve Tomas
Source:
Food chemistry 2022 v.368 pp. 130847
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; bioavailability; chlorogenic acid; food chemistry; gallic acid; gastrointestinal system; hardness; ingredients; lycopene; nutritive value; protocatechuic acid; quercetin; rutin; tomato pomace; water solubility; water uptake
Abstract:
... In this study, extruded snacks enriched with tomato pomace powder (TPP) at ratios of 5, 10, 15, and 20% (w/w) were prepared based on some preliminary experiments. The effect of tomato pomace addition to extruded snacks on the total phenolic content, total antioxidant capacity, contents of lycopene and phenolics, as well as their in vitro bioaccessibility; and additionally, physical, textural and s ...
DOI:
10.1016/j.foodchem.2021.130847

25. New approach in determination of urinary diagnostic markers for prostate cancer by MALDI-TOF/MS

Author:
M. Buszewska-Forajta; P. Pomastowski; F. Monedeiro; A. Król-Górniak; P. Adamczyk; M.J. Markuszewski; B. Buszewski
Source:
Talanta 2022 v.236 pp. 122843
ISSN:
0039-9140
Subject:
2,5-dihydroxybenzoic acid; desorption; humans; lipid composition; lipidomics; lysophosphatidylcholine; phosphatidylethanolamines; prostatic neoplasms; spectral analysis; statistical models; triacylglycerols; urine
Abstract:
... In our study, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) is proposed as a novel tool, which can be applied to analyze lipids in urine samples. For this reason, the main aim of the study was to develop and optimize the preparation protocol for urine samples in lipidomics, using urine samples obtained from patients with diagnosed cancer and non-cancer ...
DOI:
10.1016/j.talanta.2021.122843

26. Profiling of Phenolic Compounds Composition, Morphological Traits, and Antioxidant Activity of Miscanthus sacchariflorus L. Accessions

Author:
Bimal Kumar Ghimire; Erik J. Sacks; Seung Hyun Kim; Chang Yeon Yu; Ill Min Chung
Source:
Agronomy 2021 v.11 no.2 pp. -
ISSN:
2073-4395
Subject:
2,2-diphenyl-1-picrylhydrazyl; 2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Japan; Miscanthus sacchariflorus; Russia; agronomy; antioxidant activity; antioxidants; biofuels; biomass production; chemical constituents of plants; chlorogenic acid; culms; dietary supplements; ferulic acid; leaves; luteolin; metabolites; oxidants; p-coumaric acid; plant height; quercetin; rutin; China; Korean Peninsula
Abstract:
... Miscanthus sacchariflorus is a potential source of sustainable biofuel and other bioactive compounds. The high adaptive range of M. sacchariflorus may cause variation in its morphological traits and phytochemical composition. Although some metabolites have been reported from M. sacchariflorus, little is known about its phenolic compound composition and antioxidant or oxidant properties. This study ...
DOI:
10.3390/agronomy11020243

27. RP-HPLC-DAD determination of the differences in the polyphenol content of Fucus vesiculosus extracts with similar antioxidant activity

Author:
Desirée Sánchez-Bonet; Samanta García-Oms; Mariola Belda-Antolí; Carolina Padrón-Sanz; José Miguel Lloris-Carsi; Dolores Cejalvo-Lapeña
Source:
Journal of chromatography 2021 v.1184 pp. 122978
ISSN:
1570-0232
Subject:
2,5-dihydroxybenzoic acid; Fucus vesiculosus; antioxidant activity; caffeic acid; catechin; chlorogenic acid; diodes; epicatechin; ferulic acid; gallic acid; lipid peroxidation; macroalgae; oxidative stress; polyphenols; protocatechuic acid; reversed-phase high performance liquid chromatography; rutin; sustainable technology; vanillic acid
Abstract:
... Significant quantities of bioactive compounds have been found in the chemical composition of seaweeds. This source of natural antioxidants such as polyphenols appears to attenuate lipid peroxidation caused by oxidative stress, preventing the harmful effects of a number of injuries including ischemia–reperfusion (I/R). Conventional extraction (CE) has been used for years as a traditional method for ...
DOI:
10.1016/j.jchromb.2021.122978

28. Rapid and accurate profiling of oligosaccharides in beer by using a reactive matrix via MALDI-TOF MS

Author:
Ling Ling; Liyan Jiang; Qirui Chen; Bo Zhao; Yueying Li; Xinhua Guo
Source:
Food chemistry 2021 v.340 pp. 128208
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; beers; cationization; desorption; food chemistry; mass spectrometry; oligosaccharides; reproducibility; technology
Abstract:
... Oligosaccharides analysis is crucial for brewing technology. Herein, we reported a rapid and highly reproducible method for profiling of oligosaccharides in beer using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) by employing a reasonably designed reactive-matrix, 2-phenyl-3-(p-aminophenyl) acrylonitrile (PAPAN). The PAPAN enhanced ionization efficien ...
DOI:
10.1016/j.foodchem.2020.128208

29. Regional Lipid Expression Abnormalities Identified Using MALDI IMS Correspond to MRI-Defined White Matter Hyperintensities within Post-mortem Human Brain Tissues

Author:
William Pinsky; Aaron Harris; Austyn D. Roseborough; Wenxuan Wang; Ali R. Khan; Kristina Jurcic; Ken K.-C. Yeung; Stephen H. Pasternak; Shawn N. Whitehead
Source:
Analytical chemistry 2021 v.93 no.4 pp. 2652-2659
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; ammonium; analytical chemistry; axons; brain; dementia; desorption; formates; humans; ionization; lipid composition; lipids; magnetism; mass spectrometry; myelin sheath; risk; stroke; therapeutics
Abstract:
... Periventricular white matter hyperintensities (pvWMHs) are a neurological feature detected with magnetic resonance imaging that are clinically associated with an increased risk of stroke and dementia. pvWMHs represent white matter lesions characterized by regions of myelin and axon rarefaction and as such likely involve changes in lipid composition; however, these alterations remain unknown. Lipid ...
DOI:
10.1021/acs.analchem.0c05017

30. Spirogyra neglecta (Hassall) Kützing attenuates metastasis of castration-resistant human prostate cancer via the blockage of AKT signaling pathway

Author:
Punnida Arjsri; Jutarop Phetcharaburanin; Manida Suksawat; Sariya Mapoung; Chayaporn Subkamkaew; Warathit Semmarath; Supachai Yodkeeree; Pornngarm Limtrakul (Dejkriengkraikul)
Source:
South African journal of botany 2021 v.139 pp. 26-37
ISSN:
0254-6299
Subject:
2,5-dihydroxybenzoic acid; Chlorophyta; Spirogyra; botany; ethyl acetate; freshwater; gallic acid; humans; metabolomics; metastasis; prostatic neoplasms; secretion
Abstract:
... Spirogyra neglecta (Hassall) Kützing, a filamentous fresh water green alga, has clearly demonstrated its anti-inflammation properties; however, the anti-metastasis activity of this plant has not yet been elucidated. This study aimed to investigate the anti-metastasis effects of S. neglecta against castration-resistant prostate cancer cells. Transwell assays were used to determine the anti-metastas ...
DOI:
10.1016/j.sajb.2021.02.005

31. Variability in essential oil composition and phenolic acid profile of Thymus daenensis Celak. populations from Iran

Author:
Hassan Ali-Arab; Farzaneh Bahadori; Mehdi Mirza; Hassanali Naghdi Badi; Sepideh Kalate-Jari
Source:
Industrial crops and products 2022 v.178 pp. 114345
ISSN:
0926-6690
Subject:
2,5-dihydroxybenzoic acid; Thymus daenensis; caffeic acid; carvacrol; chlorogenic acid; cinnamic acid; essential oils; heat; monoterpenoids; p-coumaric acid; p-cymene; principal component analysis; rosmarinic acid; thyme; thymol; Iran
Abstract:
... Natural compounds have been widely used as food additives to replace synthetic preservatives. Essential oil (EO) and phenolic acid compounds of thyme are well known for treating a wide range of diseases. The present study was conducted to evaluate the EO yield and composition, and also phenolic acid profile for 11 populations of Thymus daenensis Celak. growing in the different areas of Iran. The E ...
DOI:
10.1016/j.indcrop.2021.114345

32. A dual-mode reactive matrix for sensitive and quantitative analysis of carbohydrates by MALDI-TOF MS

Author:
Xi Lin; Chunsheng Xiao; Ling Ling; Liming Guo; Xinhua Guo
Source:
Talanta 2021 v.235 pp. 122792
ISSN:
0039-9140
Subject:
2,5-dihydroxybenzoic acid; blood serum; desorption; humans; hydrazones; ionization; molecular weight; polysaccharides; quantitative analysis
Abstract:
... Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a widely used tool for the analysis of carbohydrates. However, the detection of carbohydrates by MALDI-TOF MS is often limited by the unsatisfactory ionization efficiency, instability and the matrix interference in low molecular weight region. Here, we demonstrate that a reactive matrix, 2-hydrazinoquino ...
DOI:
10.1016/j.talanta.2021.122792

33. The importance of Cu × Pb interactions to Lentinula edodes yield, major/trace elements accumulation and antioxidants

Author:
Monika Gąsecka; Marek Siwulski; Sylwia Budzyńska; Zuzanna Magdziak; Przemysław Niedzielski; Anna Budka; Pavel Kalač; Mirosław Mleczek
Source:
European food research & technology 2021 v.247 no.11 pp. 2799-2812
ISSN:
1438-2377
Subject:
2,5-dihydroxybenzoic acid; Lentinula edodes; antagonism; flavonoids; food research; fruits; gallic acid; protocatechuic acid; synergism; technology
Abstract:
... Due to the use of various substrates in the production of edible mushrooms which may contain metals, including Cu and Pb, it is important to understand the influence of mutual interactions between them in the process of their accumulation in fruit bodies. For this reason, the effects of Cu, Pb, and Cu × Pb on yield, accumulation of five major elements (Ca, K, Mg, Na and P), trace elements (Cu, Pb ...
DOI:
10.1007/s00217-021-03833-8

34. Accumulation of Polyphenolic Compounds and Osmolytes under Dehydration Stress and Their Implication in Redox Regulation in Four Indigenous Aromatic Rice Cultivars

Author:
Nivedita Dey; Soumen Bhattacharjee
Source:
Rice science 2020 v.27 no.4 pp. 329-344
ISSN:
1672-6308
Subject:
2,5-dihydroxybenzoic acid; Oryza sativa; apigenin; benzoic acid; betaine; biomarkers; caffeic acid; catechin; chlorogenic acid; confocal microscopy; cultivars; drought tolerance; gallic acid; homeostasis; hydrogen peroxide; indigenous species; kaempferol; myricetin; naringin; oxidation; p-coumaric acid; polyethylene glycol; polyphenols; potassium; proline; protocatechuic acid; quercetin; rice; rutin; salicylic acid; seeds; sinapic acid; superoxide anion; syringic acid; thiobarbituric acid-reactive substances; thiols; water stress; India
Abstract:
... Present work was undertaken to screen some drought tolerant indigenous aromatic rice cultivars (IARCs), commonly cultivated in West Bengal, India, based on their capacity to produce osmolytes, redox-sensitive phenolic acids and flavonoids, as contrivances for redox-regulation under drought stress. Polyethylene glycol induced post imbibitional dehydration stress mediated changes in redox regulatory ...
DOI:
10.1016/j.rsci.2020.05.008

35. Banana plant as a source of valuable antimicrobial compounds and its current applications in the food sector

Author:
Heba Sayed Mostafa
Source:
Journal of food science 2021 v.86 no.9 pp. 3778-3797
ISSN:
0022-1147
Subject:
2,5-dihydroxybenzoic acid; Musa; anti-infective agents; antioxidants; bananas; beverages; bio-packaging; biopreservatives; carene; cultivars; dopamine; ferulic acid; food industry; food storage; fruits; lupeol; meat; perishable foods; prebiotics; sucrose; value added; wastes; wheat
Abstract:
... Bananas (Musaceae) are one of the world's most common fruit crops and the oldest medicinal plants that are used to treat a variety of infections. There has been recent interest in elucidating the efficiency of the naturally active ingredients, particularly the antimicrobials, in this plant. This review begins with a short background of the banana plant and its cultivars as well as a brief descript ...
DOI:
10.1111/1750-3841.15854

36. Bioactivities and phenolic constituents relationship of Muğla thyme and pine honey of Turkey with the chemometric approach

Author:
Yusuf Sıcak; Ayşe Şahin-Yağlıoğlu; Mehmet Öztürk
Source:
Journal of food measurement & characterization 2021 v.15 no.4 pp. 3694-3707
ISSN:
2193-4126
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; alpha-tocopherol; anti-inflammatory activity; antioxidant activity; antioxidants; brain; breasts; butylated hydroxytoluene; chemometrics; chlorogenic acid; cholinesterase; cinnamic acid; colon; ethyl acetate; fluorouracil; fumaric acid; honey; measurement; neoplasm cells; odors; protocatechuic acid; salicylic acid; syringic acid; taste; therapeutics; thyme; urease; vanillic acid
Abstract:
... The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro antiproliferative, antioxidant, anticholinesterase, anti-inflammatory, tyrosinase inhibitory, and urease inhibitory activities were used to investigate the therapeutic potentials. The an ...
DOI:
10.1007/s11694-021-00940-8

37. Comparison of Phenolic Compounds, Carotenoids, Amino Acid Composition, In Vitro Antioxidant and Anti-Diabetic Activities in the Leaves of Seven Cowpea (Vigna unguiculata) Cultivars

Author:
Mapula R. Moloto; Anh Dao T. Phan; Jerry L. Shai; Yasmina Sultanbawa; Dharini Sivakumar
Source:
Foods 2020 v.9 no.9 pp. -
ISSN:
2304-8158
Subject:
2,5-dihydroxybenzoic acid; Vigna unguiculata; alpha-amylase; amino acid composition; antioxidant activity; antioxidants; assays; correlation; cowpeas; cultivars; cytotoxicity; essential amino acids; functional foods; gene expression; genotype; glucose transporters; glycemic effect; information; ingredients; insulin; leaf extracts; leaves; lutein; metabolites; myocytes; nutrition; quercetin; risk reduction; skeletal muscle; Sub-Saharan Africa
Abstract:
... Cowpea is a well-known nutrition rich African leafy vegetable that has potential to sustain food and nutrition insecurity in sub-Saharan Africa. Consumption of cowpea legumes is associated with reduced risk of type 2 diabetes mellitus. Therefore, the present study was designed to evaluate the (i) variation in phenolic metabolites in seven cowpea cultivars (VOP1, VOP2, VOP3, VOP4, VOP5, VOP7, and V ...
DOI:
10.3390/foods9091285

38. Determination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets

Author:
Moritz Janda; Brandon K. B. Seah; Dennis Jakob; Janine Beckmann; Benedikt Geier; Manuel Liebeke
Source:
Analytical chemistry 2021 v.93 no.24 pp. 8399-8407
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; analytical chemistry; automation; computer software; data collection; desorption; ionization; matrix-assisted laser desorption-ionization mass spectrometry; metabolites; metabolome; metabolomics; potassium; sodium
Abstract:
... Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of m/z values, which is substantially complicated by background ions introduced throughout the chemicals and equipment used during experimental procedures. Among many factors, the formation of adducts with sodi ...
DOI:
10.1021/acs.analchem.0c04720

39. Divergent Synthesis of Natural Benzyl Salicylate and Benzyl Gentisate Glucosides

Author:
Dariya D. Fedorova; Dariya S. Nazarova; David L. Avetyan; Andrey Shatskiy; Maxim L. Belyanin; Markus D. Kärkäs; Elena V. Stepanova
Source:
Journal of natural products 2020 v.83 no.10 pp. 3173-3180
ISSN:
1520-6025
Subject:
2,5-dihydroxybenzoic acid; Populus balsamifera; Salix; glucosides; metabolites; rare species; sugars
Abstract:
... Herein is reported the first total synthesis of benzyl salicylate and benzyl gentisate glucosides present in various plant species, in particular the Salix genus, such as Populus balsamifera and P. trichocarpa. The method permits the synthesis of several natural phenolic acid derivatives and their glucosides starting from salicylic or gentisic acid. The divergent approach afforded access to three ...
DOI:
10.1021/acs.jnatprod.0c00838

40. Elderberry (Sambucus nigra L.) as potential source of antioxidants. Characterization, optimization of extraction parameters and bioactive properties

Author:
Rubén Domínguez; Leilei Zhang; Gabriele Rocchetti; Luigi Lucini; Mirian Pateiro; Paulo E.S. Munekata; José M. Lorenzo
Source:
Food chemistry 2020 v.330 pp. 127266
ISSN:
0308-8146
Subject:
2,5-dihydroxybenzoic acid; Sambucus nigra; anthocyanins; antioxidant activity; antioxidants; carotenoids; elderberries; ethanol; experimental design; gallic acid; nutritive value; pH; polyunsaturated fatty acids; proteins; quercetin; response surface methodology; rutin; temperature; total soluble solids
Abstract:
... The present study aimed to characterize the nutritional value and potential use of elderberries as a source of antioxidant compounds. The chemical composition, fatty acids and phenolic compounds were determined for elderberries. The optimization of extraction parameters was designed with a Box-Behnken design coupled with response surface methodology (RSM) and desirability function analysis. The pr ...
DOI:
10.1016/j.foodchem.2020.127266

41. Endophytic Alcaligenes faecalis mediated redesigning of host defense itinerary against Sclerotium rolfsii through induction of phenolics and antioxidant enzymes

Author:
Shatrupa Ray; Prashant Swapnil; Prachi Singh; Surendra Singh; Birinchi Kumar Sarma; Harikesh Bahadur Singh
Source:
Biological control 2020 v.150 pp. 104355
ISSN:
1049-9644
Subject:
2,5-dihydroxybenzoic acid; Alcaligenes faecalis; Athelia rolfsii; Sclerotium (genus); antioxidant enzymes; biological control; endophytes; ferulic acid; hosts; kaempferol; leaves; lignification; microorganisms; okra; peroxidase; quercetin; rutin; superoxide dismutase
Abstract:
... Endophytic microbes intricately modulate host defense pathways upon challenge with any form of environmental stress. In the current study, endophytic Alcaligenes faecalis treated okra plants were found to exhibit significant resistance to cell-lysis and disintegration upon infection with Sclerotium rolfsii. Apart from the morphological amendments, a systemic induction in phenolic content was obser ...
DOI:
10.1016/j.biocontrol.2020.104355

42. Evaluation of phytotherapeutic activities and phytochemical content of Phormidium autumnale Gomont from natural freshwater sources

Author:
Dilek Yalcin; Hikmet Türk Katircioğlu; Tülay Özer; Minoo Pourhassan Shamchi; İlkay Acikgoz Erkaya
Source:
Environmental monitoring and assessment 2020 v.192 no.4 pp. 244
ISSN:
0167-6369
Subject:
2,5-dihydroxybenzoic acid; 4-hydroxybenzoic acid; Enterococcus faecalis; Escherichia coli; Fourier transform infrared spectroscopy; Phormidium autumnale; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus agalactiae; acetone; active ingredients; antibacterial properties; antibiotic resistance; bacteria; bioactive compounds; catechin; cyclic peptides; freshwater; metabolites; methanol; methicillin; minimum inhibitory concentration; p-coumaric acid; phytotherapy; ribosomal DNA; sequence analysis; solvents; vanillic acid; Turkey (country)
Abstract:
... The information available on microalgae-sourced compounds, especially antibiotics and other bioactive compounds, and their potential commercial applications is still insufficient. In this study, antibacterial activity, metabolites, and molecular characterization of Phormidium autumnale, which was isolated from samples collected from different natural freshwater sources in Ankara, Turkey, were inve ...
DOI:
10.1007/s10661-020-8207-4

43. Ganoderma carnosum and Ganoderma pfeifferi: Metal concentration, phenolic content, and biological activity

Author:
Omer Umit Yalcin; Cengiz Sarikurkcu; Mustafa Cengiz; Halil Gungor; Sanja Ćavar Zeljković
Source:
Mycologia 2020 v.112 no.1 pp. 1-8
ISSN:
1557-2536
Subject:
2,5-dihydroxybenzoic acid; antioxidant activity; chemical analysis; enzyme inhibition; flavonoids; vanillic acid
Abstract:
... Medicinal Ganoderma mushrooms have long tradition in Asia, and recently they began to be consumed in Europe as well. Among hundreds of Ganoderma species, only a few of them are intensively investigated, i.e., G. lucidum and G. applanatum, whereas the chemistry and bioactivities of the other species, especially of European origin, still remain unknown. This study comprises detailed chemical analysi ...
DOI:
10.1080/00275514.2019.1689748

44. Identification and Characterization of Polyphenols from Carissa spinarum Fruit and Evaluation of Their Antioxidant and Anti-quorum Sensing Activity

Author:
Maria Sheeba Nazareth; S. V. Shreelakshmi; Nandini P. Shetty
Source:
Current microbiology 2021 v.78 no.4 pp. 1277-1285
ISSN:
0343-8651
Subject:
2,5-dihydroxybenzoic acid; Carissa spinarum; Chromobacterium violaceum; Pseudomonas aeruginosa; Yersinia enterocolitica; antibiotic resistance; antioxidant activity; antioxidants; biofilm; chemical constituents of plants; epicatechin; food spoilage; fruit extracts; fruits; humans; polyphenols; quercetin; resveratrol; syringic acid; violacein; virulence
Abstract:
... Quorum sensing controls bacterial virulence through signaling molecules, which plays a vital role in managing foodborne pathogens that cause food spoilage and human infections. Though many synthetic compounds have been used to control infection, antibiotic resistance has become a global issue. Targeting the bacterial quorum sensing using the bioactive compounds could be an alternative strategy to ...
DOI:
10.1007/s00284-021-02381-4

45. In vitro study of genotoxic and cytotoxic activities of methanol extracts of Artemisia vulgaris L. and Artemisia alba Turra

Author:
Marina Radović Jakovljević; Darko Grujičić; Jovana Tubić Vukajlović; Aleksandra Marković; Milena Milutinović; Milan Stanković; Nenad Vuković; Milena Vukić; Olivera Milošević-Djordjević
Source:
South African journal of botany 2020 v.132 pp. 117-126
ISSN:
0254-6299
Subject:
2,5-dihydroxybenzoic acid; Artemisia vulgaris; assays; chemical composition; chlorogenic acid; chronic exposure; colorectal neoplasms; cytotoxicity; exhibitions; extracts; flavonoids; frequency; high performance liquid chromatography; humans; in vitro studies; ligaments; lymphocytes; methanol; micronucleus tests; mitomycin; mutagens; neoplasm cells; polyphenols; spectrophotometers; stem cells; viability
Abstract:
... The aim of the study was to investigate genotoxic and cytotoxic activities of Artemisia vulgaris L. and Artemisia alba Turra methanol extracts concerning their chemical composition, separately and in co-treatment with a known mutagen (mitomycin C, MMC). For these evaluations, the cytokinesis-block micronucleus (CBMN) assay as the method for measuring MN frequency in human peripheral blood lymphocy ...
DOI:
10.1016/j.sajb.2020.04.016

46. In vivo and in vitro evaluation of the osteogenic potential of Davallia mariesii T. Moore ex Baker

Author:
Yi-Tzu Lin; Shih-Wen Peng; Zuha Imtiyaz; Chin-Wen Ho; Wen-Fei Chiou; Mei-Hsien Lee
Source:
Journal of ethnopharmacology 2021 v.264 pp. 113126
ISSN:
0378-8741
Subject:
2,5-dihydroxybenzoic acid; Davallia; Oriental traditional medicine; active ingredients; alkaline phosphatase; bioactive compounds; bone formation; bone health; bone morphogenetic proteins; bone resorption; cell viability; enzyme activity; estrogens; femur; fractionation; herbal medicines; human cell lines; in vitro studies; in vivo studies; liquid chromatography; mice; micro-computed tomography; mineralization; osteoblasts; osteoclasts; osteopontin; osteoporosis; ovariectomy; phytochemicals; postmenopause; quantitative analysis; quantitative polymerase chain reaction; rhizomes; tandem mass spectrometry; toxicity testing; transcription factor NF-kappa B; vertebrae
Abstract:
... Postmenopausal osteoporosis is a major bone health issue worldwide. There is an unmet medical need for osteoporosis treatments, a disease which disproportionately impacts women. Exploring botanicals to prevent or treat osteoporosis is currently an interest of investigations. Rhizomes of Davallia mariesii T. Moore ex Baker (Davalliacea) are used an indigenous herbal medicine in Asia for injuries du ...
DOI:
10.1016/j.jep.2020.113126

47. Influence of calcium channel modulators on the production of serotonin, gentisic acid, and a few other biosynthetically related phenolic metabolites in seedling leaves of salt tolerant rice variety Nonabokra

Author:
Poulami Gupta; Bratati De
Source:
Plant signaling & behavior 2021 v.16 no.10 pp. 1929732
ISSN:
1559-2324
Subject:
2,5-dihydroxybenzoic acid; behavior; calcium; calcium channels; calcium ionophores; culture media; hydroponics; lanthanum; metabolites; metabolomics; rice; salinity; salt stress; salt tolerance; seedlings; serotonin; sodium; sodium chloride; sulfates; vanadyl ions; verapamil
Abstract:
... Rice, a most salt-sensitive cereal plant, adopts diverse pathways to withstand sodium chloride–induced salinity-related adversities. During the present study, attempt was made to understand the role of calcium on metabolite profile of the leaves of salt tolerant rice seedlings of variety of Nonabokra under sodium chloride induced salinity, by Gas Chromatography–Mass Spectrometry-based metabolomics ...
DOI:
10.1080/15592324.2021.1929732

48. Lipid composition and some bioactivities of 3 newly isolated microalgae (Tetraselmis sp. IMP3, Tetraselmis sp. CTP4, and Skeletonema sp.)

Author:
C. Cardoso; H. Pereira; J. Franca; J. Matos; I. Monteiro; P. Pousão-Ferreira; A. Gomes; L. Barreira; J. Varela; N. Neng; J. M. Nogueira; C. Afonso; N. M. Bandarra
Source:
Aquaculture international 2020 v.28 no.2 pp. 711-727
ISSN:
0967-6120
Subject:
2,5-dihydroxybenzoic acid; Skeletonema; Tetraselmis; alpha-linolenic acid; anti-inflammatory activity; antioxidant activity; aquaculture; biomass; dietary supplements; eicosapentaenoic acid; feedstocks; iron; linoleic acid; lipid composition; microalgae; myristic acid; oleic acid; palmitic acid; polyphenols; prostaglandin synthase
Abstract:
... Recently isolated microalgae Tetraselmis sp. IMP3, Tetraselmis sp. CTP4, and Skeletonema sp. were studied. The three novel strains contained relatively high levels of polyunsaturated fatty acids (PUFA) and n3 PUFA. However, highly unsaturated n3 FA contents were relatively low (5.7–13.0% of the total FA). In general, eicosapentaenoic acid (EPA, 20:5 n3) contents were low (< 6.4% of the total FA). ...
DOI:
10.1007/s10499-019-00489-w

49. Monolithic Gold Nanoparticles/Thiol-β-cyclodextrin-Functionalized TiO₂ Nanowires for Enhanced SALDI MS Detection and Imaging of Natural Products

Author:
Xian-Na Wang; Bin Li
Source:
Analytical chemistry 2021 v.94 no.2 pp. 952-959
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; Mentha spicata; Moschus; analytical chemistry; bile; chemical species; desorption; detection limit; glass; gold; indium tin oxide; ionization; mass spectrometry; nanowires; potatoes; sol-gel processing
Abstract:
... Surface-assisted laser desorption/ionization mass spectrometry (SALDI MS) has been successfully applied in the analysis of various small molecules. In this work, gold nanoparticles/thiol-β-cyclodextrin-functionalized TiO₂ nanowires (AuNPs/SH-β-CD-TiO₂ NWs) were prepared to enhance the performance of SALDI MS and mass spectrometry imaging (MSI). A monolithic TiO₂ film was first grown on an indium t ...
DOI:
10.1021/acs.analchem.1c03764

50. On-MALDI-Target N-Glycan Nonreductive Amination by 2-Aminobenzoic Acid

Author:
Xiaoping L Hronowski; Yan Wang; Zoran Sosic; Ru Wei
Source:
Analytical chemistry 2020 v.92 no.15 pp. 10252-10256
ISSN:
1520-6882
Subject:
2,5-dihydroxybenzoic acid; amination; analytical chemistry; derivatization; glycomics; glycoproteins; labor; mass spectrometry; monoclonal antibodies; polysaccharides; sodium
Abstract:
... 2-Aminobenzoic acid (2-AA) is widely used as a labeling reagent to derivatize released N-glycans at their free reducing terminus by reductive amination. 2-AA-labeled glycans have increased mass spectrometric sensitivity for their identification and enable fluorescence-chromatography-based glycan quantification. Drawbacks are that the labeling process is labor intensive and time consuming. Clean up ...
DOI:
10.1021/acs.analchem.0c01748