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You searched for: Subject Bitis arietans Remove constraint Subject: Bitis arietans Subject Combretum Remove constraint Subject: Combretum Subject Democratic Republic of the Congo Remove constraint Subject: Democratic Republic of the Congo
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1. Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa

Author:
Marianne Molander; Line Nielsen; Søren Søgaard; Dan Staerk; Nina Rønsted; Drissa Diallo; Kusamba Zacharie Chifundera; Johannes van Staden; Anna K. Jäger
Source:
Journal of ethnopharmacology 2014 v.157 pp. 171-180
ISSN:
0378-8741
Subject:
Bauhinia thonningii; Bitis arietans; Combretum; Grewia mollis; Lannea; Naja; Strychnos; active ingredients; antiserum; bioassays; enzyme inhibition; enzyme inhibitors; ethanol; hyaluronoglucosaminidase; inhibitory concentration 50; mortality; necrosis; patients; phospholipase A2; plant anatomy; polyphenols; proteinases; snake bites; snakes; traditional medicine; Democratic Republic of the Congo; Mali; South Africa
Abstract:
... Snakebite envenomation, every year, causes estimated 5–10,000 mortalities and results in more than 5–15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional ...
DOI:
10.1016/j.jep.2014.09.027