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1. Aeromonas salmonicida aptamer selection and construction for colorimetric and ratiometric fluorescence dual-model aptasensor combined with g-C3N4 and G-quadruplex

Author:
Qiujun Lu; Shengnan Zhang; Yuzhen Ouyang; Chun Zhang; Meiling Liu; Youyu Zhang; Le Deng
Source:
Talanta 2023 v.252 pp. 123857
ISSN:
0039-9140
Subject:
Aeromonas salmonicida; Danio rerio; aptasensors; aquaculture; color; colorimetry; detection limit; early diagnosis; fluorescence; food safety; oligonucleotides; opportunistic pathogens; rapid methods; single-stranded DNA; systematic evolution of ligands by exponential enrichment
Abstract:
... Aeromonas salmonicida (A. salmonicida) is an important opportunistic pathogen to aquatic animals that causes severe economic losses to aquaculture, which makes its rapid detection and prevention are critical. In this work, a single-stranded DNA (ssDNA) aptamer (A.s-2) with high specificity to the bacteria was selected by Systematic Evolution of Ligands by Exponential Enrichment (SELEX). The select ...
DOI:
10.1016/j.talanta.2022.123857

2. Alleviative effects of a novel strain Bacillus coagulans XY2 on copper-induced toxicity in zebrafish larvae

Author:
Fang Ai; Xuedi Huang; Yalan Wu; Chen Ji; Yufang Gao; Ting Yu; Fujie Yan
Source:
Journal of environmental sciences (China) 2023 v.125 pp. 750-760
ISSN:
1001-0742
Subject:
Bacillus coagulans; Danio rerio; antioxidant activity; genes; human health; humans; inflammation; interleukin-10; intestines; metabolism; models; mortality; neutrophils; oxidative stress; pollutants; probiotics; toxicity; transcription (genetics); China
Abstract:
... Copper (Cu) is a kind of micronutrient element that is essential for human metabolism. However, it is also considered as an environmental pollutant which is toxic to organisms at a high concentration level. Probiotics, regarded as beneficial microorganisms for promoting human health, have functions of antioxidant capacity, immune-enhancing properties, intestinal barrier protection and regulation. ...
DOI:
10.1016/j.jes.2022.02.010

3. Anti-inflammatory and immunostimulant effect of different timing-related administration of dietary polyphenols on intestinal inflammation in zebrafish, Danio rerio

Author:
Roberta Imperatore; Graziella Orso; Serena Facchiano; Pierpaolo Scarano; Seyed Hossein Hoseinifar; Ghasem Ashouri; Carmine Guarino; Marina Paolucci
Source:
Aquaculture 2023 v.563 pp. 738878
ISSN:
0044-8486
Subject:
Castanea sativa; Danio rerio; Verbascum; adults; antioxidant activity; antioxidants; aquaculture; assets; catalase; diet; feed additives; flavonoids; gene expression; immunostimulants; inflammation; interleukin-10; intestines; mitogen-activated protein kinase; models; phosphorylation; polyphenols; prostaglandin synthase; superoxide dismutase; transcription factor NF-kappa B; tumor necrosis factors
Abstract:
... A short-term study was performed to assess the effects of diets supplemented with polyphenols (CSVP), extracted from the chestnut (Castanea sativa) shell, agri-food waste rich in tannins, and mullein (Verbascum macrurum), a perennial spontaneous plant rich in flavonoids, on a zebrafish (Danio rerio) model of k-carrageenan-induced intestinal inflammation. Morphological asset of intestine, immunoden ...
DOI:
10.1016/j.aquaculture.2022.738878

4. Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evaluation

Author:
Shanshan Zhu; Zhichang Qiu; Xuguang Qiao; Geoffrey I.N. Waterhouse; Wenqing Zhu; Wenting Zhao; Qiuxia He; Zhenjia Zheng
Source:
Food science and human wellness 2023 v.12 no.2 pp. 454-466
ISSN:
2213-4530
Subject:
Arctium lappa; Danio rerio; anti-inflammatory activity; food science; gene expression; humans; hydrogen; hydrophobicity; inflammation; interleukin-8; models; nanoparticles; oleanolic acid; pH; particle size; polysaccharides; storage quality; temperature; ursolic acid; water solubility; zeta potential
Abstract:
... This study explored the potential of polysaccharides from Actium lappa (ALPs) as natural wall materials for producing ALP-based nanoparticles to deliver poorly water-soluble oleanolic acid (OA) and ursolic acid (UA). Encapsulating OA+UA with ALPs (ALP:OA+UA, 50:1; OA:UA, 1:1) changed the crystalline nature to a more amorphous state through hydrogen bonding and involving O–H/C–O/O–C–O groups. ALP-O ...
DOI:
10.1016/j.fshw.2022.07.047

5. Developmental toxicity of TCBPA on the nervous and cardiovascular systems of zebrafish (Danio rerio): A combination of transcriptomic and metabolomics

Author:
Wentao Liu; Yifan Pan; Lu Yang; Yun Xie; Xuanyue Chen; Jing Chang; Weiyu Hao; Lifei Zhu; Bin Wan
Source:
Journal of environmental sciences (China) 2023 v.127 pp. 197-209
ISSN:
1001-0742
Subject:
Danio rerio; blood; developmental toxicity; flame retardants; focal adhesions; humans; metabolomics; transcriptomics; China
Abstract:
... Tetrachlorobisphenol A (TCBPA), a widely used halogenated flame retardant, is frequently detected in environmental compartments and human samples. However, unknown developmental toxicity and mechanisms limit the entire understanding of its effects. In this study, zebrafish (Danio rerio) embryos were exposed to various concentrations of TCBPA while a combination of transcriptomics, behavioral and b ...
DOI:
10.1016/j.jes.2022.04.022

6. Ethalfluralin induces developmental toxicity in zebrafish via oxidative stress and inflammation

Author:
Taeyeon Hong; Hahyun Park; Garam An; Gwonhwa Song; Whasun Lim
Source:
Science of the total environment 2023 v.854 pp. 158780
ISSN:
0048-9697
Subject:
Danio rerio; acridine orange; angiogenesis; apoptosis; blood vessels; brain; developmental toxicity; edema; embryogenesis; environment; ethalfluralin; gene expression; genetically modified organisms; heart; heart rate; inflammation; interleukin-8; intestines; mitochondria; oxidative stress; quantitative polymerase chain reaction; reactive oxygen species; survival rate; vertebrates; weeds; yolk sac
Abstract:
... Ethalfluralin, of dinitroaniline herbicide family, is an effective weed controller. Following residue detection in herbicide-treated fields, ethalfluralin was reported to interfere with early stages of implantation in some vertebrate species. However, the role of ethalfluralin in the development of zebrafish embryos has not been elucidated yet. Therefore, in the present study, we investigated the ...
DOI:
10.1016/j.scitotenv.2022.158780

7. Exposure of zebrafish (Danio rerio) to trans-2-hexenal induces oxidative stress and protein degeneration of the gill

Author:
Dicheng Ma; Haiyan Yu; Guangrui Cui; Jiamei Zhu; Bingyu Zhu; Wei Mu; Feng Liu
Source:
Science of the total environment 2023 v.854 pp. 158813
ISSN:
0048-9697
Subject:
Danio rerio; biopesticides; cell death; chronic toxicity; denaturation; environment; intravenous injection; malondialdehyde; methionine; mortality; oral administration; oxidative stress; protein denaturation; risk; risk assessment; succinate dehydrogenase (quinone)
Abstract:
... Trans-2-hexenal (T2H) has great commercial value for development as a biopesticide, but its toxicity risk to nontarget organisms is unknown. Here, the toxicity and underlying mechanism of T2H on zebrafish (Danio rerio) were investigated. The LC₅₀ (48 h) of T2H on zebrafish is 4.316 μg/mL, and the aldehyde group is essential to its toxicity. In 14-day chronic toxicity tests, 0.432 μg/mL T2H resulte ...
DOI:
10.1016/j.scitotenv.2022.158813

8. Fate of progesterone and norgestrel in anaerobic/anoxic/oxic (A/A/O) process: Insights from biotransformation and mass flow

Author:
Xianda Hu; Jinju Geng; Fuzheng Zhao; Chao Min; Linchang Guan; Qingmiao Yu; Hongqiang Ren
Source:
Science of the total environment 2023 v.856 pp. 158844
ISSN:
0048-9697
Subject:
Danio rerio; biotransformation; dehydrogenation; environment; isomerization; mass flow; progesterone; wastewater; wastewater treatment
Abstract:
... Progesterone (P4) and norgestrel (NGT) are two steroid progestogens that can pose adverse effects on aquatic organisms at ng/L levels. Despite increasing concern on their occurrence and removal in wastewater, their fate in the wastewater treatment process has not been well documented. This study identified the transformation products (TPs) of P4 and NGT in anaerobic/anoxic/oxic (A/A/O) process. Po ...
DOI:
10.1016/j.scitotenv.2022.158844

9. Global warming and glyphosate toxicity (II): Offspring zebrafish modelling with behavioral, morphological and immunohistochemical approaches

Author:
Ekrem Sulukan; Alper Baran; Meryem Kankaynar; Tuğba Kızıltan; İsmail Bolat; Serkan Yıldırım; Hacer Akgül Ceyhun; Saltuk Buğrahan Ceyhun
Source:
Science of the total environment 2023 v.856 pp. 158903
ISSN:
0048-9697
Subject:
Danio rerio; adults; apoptosis; aquatic ecosystems; blood flow; environment; fish; glyphosate; heart rate; immunohistochemistry; lipids; locomotion; models; mouth; progeny; reactive oxygen species; serotonin; survival rate; temperature; thigmotaxis; toxicity
Abstract:
... The increase in temperature due to global warming greatly affects the toxicity produced by pesticides in the aquatic ecosystem. Studies investigating the effects of such environmental stress factors on next generations are important in terms of the sustainability of ecosystems. In this study, the effects of parental synergistic exposure to glyphosate and temperature increase on the next generation ...
DOI:
10.1016/j.scitotenv.2022.158903

10. Joint effects of micro-sized polystyrene and chlorpyrifos on zebrafish based on multiple endpoints and gut microbial effects

Author:
Zhiyi Huang; Xiangxiang Xiao; Dali Wang; Yuheng Zhong; Qi Ding; Jing You
Source:
Journal of environmental sciences (China) 2023 v.126 pp. 184-197
ISSN:
1001-0742
Subject:
Danio rerio; adsorption; aquatic environment; chlorpyrifos; fish; histology; intestinal microorganisms; liver; microbial communities; microplastics; oxidative stress; polystyrenes; toxicology; wildlife; China
Abstract:
... Microplastics often co-occur with a variety of organic contaminants in aquatic environment and pose combined risks to aquatic wildlife. Here, we investigated joint effects of micro-sized polystyrene (mPS, 5 µm) and an organophosphate pesticide chlorpyrifos on zebrafish, using multiple endpoints at both fish individual and gut microbiota levels. It was revealed that mPS ingested by zebrafish accumu ...
DOI:
10.1016/j.jes.2022.06.001

11. Lysozyme-encapsulated gold nanoclusters for ultrasensitive detection of folic acid and in vivo imaging

Author:
Wenyan Li; Xingzhuo Zhou; Wenjun Yan; Ruihan Wang; Zeqian Yang; Yongchong Hu; Yang Liu; Zhichao Jia; Yingqi Li
Source:
Talanta 2023 v.251 pp. 123789
ISSN:
0039-9140
Subject:
Danio rerio; bioaccumulation; detection limit; fluorescence; folic acid; hyaluronic acid; intestines; liver; lysosomes; nanogold; neoplasms; toxicity
Abstract:
... Herein, lysozyme-encapsulated gold nanoclusters (AuNCs@Lzm, AuL) were favorably obtained by a simple and economical synthesis. The resulting AuL exhibits low toxicity, exceptional stability and intense red fluorescence at 650 nm, which can enter living cells and is mainly located in lysosomes. The AuL selectively and sensitively drove to detect folic acid (FA) with a detection limit as low as 0.19 ...
DOI:
10.1016/j.talanta.2022.123789

12. Magnetically propelled chained nanocomposites for biologically relevant media exploration

Author:
Miguel A. Ramos-Docampo; Pablo Hurtado; Ana B. Dávila-Ibáñez; Roberto Piñeiro; Mónica L. Fanarraga; Verónica Salgueiriño
Source:
Journal of colloid and interface science 2023 v.629 pp. 287-296
ISSN:
0021-9797
Subject:
Danio rerio; cytosol; drugs; fibroblasts; glycerol; heat; magnetic fields; magnetic separation; mice; nanocomposites; nanomaterials; viscosity
Abstract:
... Elongated nanostructures to be remotely and magnetically propelled in biologically relevant media, have gained attention as offering themselves as effective tools or carriers in theragnostics applications. However, the magnetic actuation associated remains challenging due to the lack of mechanical information in the media of interest, taking into account biophysical or biomedical purposes. In this ...
DOI:
10.1016/j.jcis.2022.08.154

13. Mepanipyrim induces cardiotoxicity of zebrafish (Danio rerio) larvae via promoting AhR-regulated COX expression pathway

Author:
Chao Shen; Jing He; Kongyang Zhu; Naying Zheng; Yue Yu; Chengyong He; Chunyan Yang; Zhenghong Zuo
Source:
Journal of environmental sciences (China) 2023 v.125 pp. 650-661
ISSN:
1001-0742
Subject:
Danio rerio; agonists; antagonists; bioassays; calcium; cardiomyocytes; cardiotoxicity; electron transport chain; gene expression; heart rate; human health; mepanipyrim; mitochondria; toxicity; viticulture; China
Abstract:
... The wide use of pesticides has seriously threatened human health and the survival of beneficial organisms. The fungicide mepanipyrim is widely used in viticulture practices. Studies of mepanipyrim-induced toxicity in organisms are still scarce, especially studies on cardiotoxicity. In this study, we aimed to investigate mepanipyrim-induced cardiotoxicity in zebrafish (Danio rerio) larvae. We found ...
DOI:
10.1016/j.jes.2022.01.012

14. Mepanipyrim induces visual developmental toxicity and vision-guided behavioral alteration in zebrafish larvae

Author:
Chao Shen; Yimei Cai; Jialing Li; Chengyong He; Zhenghong Zuo
Source:
Journal of environmental sciences (China) 2023 v.124 pp. 76-88
ISSN:
1001-0742
Subject:
Danio rerio; anilinopyrimidine fungicides; aryl hydrocarbon receptors; developmental toxicity; fruit growing; fungi; genes; light intensity; mepanipyrim; opsin; phototransduction; quantitative polymerase chain reaction; transcriptomics; wavelengths; China
Abstract:
... Mepanipyrim, an anilinopyrimidine fungicide, has been extensively used to prevent fungal diseases in fruit culture. Currently, research on mepanipyrim-induced toxicity in organisms is still very scarce, especially visual developmental toxicity. Here, zebrafish larvae were employed to investigate mepanipyrim-induced visual developmental toxicity. Intense light and monochromatic light stimuli-evoked ...
DOI:
10.1016/j.jes.2021.11.008

15. Nuclease treatment enhances the probiotic effect of Bacillus velezensis T23 on hepatic steatosis and inflammation induced by high-fat diet in zebrafish

Author:
Fengli Zhang; Yinyin Luan; Qiang Hao; Qingshuang Zhang; Yalin Yang; Chao Ran; Zhen Zhang; Zhigang Zhou
Source:
Aquaculture 2023 v.562 pp. 738801
ISSN:
0044-8486
Subject:
Bacillus velezensis; Danio rerio; antioxidant activity; aquaculture; complement; fatty liver; fermented foods; high fat diet; immunity; inflammation; interleukin-6; intestinal microorganisms; intestines; lipogenesis; liver; lysozyme; mucus; nucleotides; probiotics; weight gain
Abstract:
... Metabolic diseases caused by high-fat diet (HFD) have been a major problem currently in aquaculture. Nucleotides have been used as functional nutrients to improve the growth and health of fish，such as stimulating immune responses, such as immune cells and complement lytic activity. In this experiment, we supplemented solid fermentation product of Bacillus velezensis T23 and nuclease-treated Bacill ...
DOI:
10.1016/j.aquaculture.2022.738801

16. Nucleus-targeting pH-Responsive carbon dots for fast nucleus pH detection

Author:
Samran Durrani; Zihuayuan Yang; Jie Zhang; Zihao Wang; Haiyan Wang; Faran Durrani; Fu-Gen Wu; Fengming Lin
Source:
Talanta 2023 v.252 pp. 123855
ISSN:
0039-9140
Subject:
Alzheimer disease; Danio rerio; RNA; carbon; cell nucleolus; endocytosis; fluorescence; heart diseases; light intensity; lipids; pH; photoluminescence
Abstract:
... Nucleus pH is closely linked to many diseases such as aging, heart disease, skeletal myopathies, cancer, Alzheimer's disease, etc. Nevertheless, fluorescent sensors that can directly monitor nucleus pH changes have not yet been reported. Here, we first reported a green emissive carbon dots (CDs) for nucleus pH detection in living cells. CDs can selectively target nucleus with high accumulation at ...
DOI:
10.1016/j.talanta.2022.123855

17. Parental and transgenerational impairments of thyroid endocrine system in zebrafish by 2,4,6-tribromophenol

Author:
Yuxi Zhou; Juanjuan Fu; Min Wang; Yongyong Guo; Lihua Yang; Jian Han; Bingsheng Zhou
Source:
Journal of environmental sciences (China) 2023 v.124 pp. 291-299
ISSN:
1001-0742
Subject:
Danio rerio; adults; bioaccumulation; brain; chemical analysis; flame retardants; histopathology; humans; liver; pollution; progeny; toxicity; transcription (genetics); China
Abstract:
... Many environmental contaminants could be transmitted from parents and generate impairments to their progeny. The 2,4,6-tribromophenol (TBP), a novel brominated flame retardant which has been frequently detected in various organisms, was supposed to be bioaccumulated and intergenerational transmitted in human beings. Previous studies revealed that TBP could disrupt thyroid endocrine system in zebra ...
DOI:
10.1016/j.jes.2021.09.022

18. Pathogenic infection and microbial composition of yellow catfish (Pelteobagrus fulvidraco) challenged by Aeromonas veronii and Proteus mirabilis

Author:
Wanying Zhai; Qian Wang; Xinpeng Zhu; Xiaoying Jia; Liangbiao Chen
Source:
Aquaculture and fisheries 2023 v.8 no.2 pp. 166-173
ISSN:
2468-550X
Subject:
Aeromonas veronii; Danio rerio; Ictalurus punctatus; Moraxella; Proteus mirabilis; Tachysurus fulvidraco; Vibrio; bacterial communities; catfish; disease prevention; freshwater fish; intraperitoneal injection; microbiome; mortality; mucus; pathogenicity; China
Abstract:
... The catfishes are a group of economically important freshwater fish in China, which in recent years have suffered heavy losses as a result of bacterial outbreaks. In this study, we examined the diversity of the microbiome of infected skin mucus of yellow catfish (Pelteobagrus fulvidraco) and channel catfish (Ictalurus punctatus) and analyzed the bacterial pathogens. We found several common pathoge ...
DOI:
10.1016/j.aaf.2021.05.007

19. Silica crystals activate toll-like receptors and inflammasomes to promote local and systemic immune responses in zebrafish

Author:
Sylwia D. Tyrkalska; Annamaria Pedoto; Alicia Martínez-López; José A. Ros-Lucas; Pablo Mesa-del-Castillo; Sergio Candel; Victoriano Mulero
Source:
Developmental and comparative immunology 2023 v.138 pp. 104523
ISSN:
0145-305X
Subject:
Danio rerio; brain; immune system; immunology; inflammasomes; inflammation; models; pyroptosis; respiratory tract diseases; silica
Abstract:
... Silica crystals are potent activators of the inflammasome that cause a fibrotic lung disease, called silicosis, with no effective treatment available. We report here that injection of silica crystals into the hindbrain ventricle of zebrafish embryos led to the initiation of local and systemic immune responses driven through both Toll-like receptors (TLR)- and inflammasome-dependent signaling pathw ...
DOI:
10.1016/j.dci.2022.104523

20. TLR5M cooperates with TLR5S to activate NF-κB in Nile tilapia (Oreochromis niloticus)

Author:
Zijiong Dong; Jiadong Li; Ruhuang Deng; Zhenzhen Zhang; Jianlin Chen; Yang Lei; Liting Wu; Zheng Guo; Bei Wang; Bingxi Li; Fang Liang; Jianmin Ye
Source:
Aquaculture 2023 v.562 pp. 738775
ISSN:
0044-8486
Subject:
Aeromonas hydrophila; Danio rerio; Oreochromis niloticus; Toll-like receptor 5; aquaculture; brain; cell membranes; cytokines; disease prevention; fish; flagellin; kidneys; liver; macrophages; monocytes; pathogens; spleen
Abstract:
... The binding of flagellin to receptor TLR5 (Toll-like receptor 5) on the cell surface is a prerequisite for the pathogen infection to the body, which has important implication for disease prevention. Unlike mammals, teleost TLR5 exists in two different forms: membrane-bound TLR5M (membrane TLR5, TLR5M) and secreted TLR5S (soluble TLR5, TLR5S). In this study, TLR5M and TLR5S from Nile tilapia (Oreoc ...
DOI:
10.1016/j.aquaculture.2022.738775