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1. Arabidopsis F‐BOX STRESS INDUCED 4 is required to repress excessive divisions in stomatal development

Author:
Yi Li; Shan Xue; Qixiumei He; Junxue Wang; Lingling Zhu; Junjie Zou; Jie Zhang; Chaoran Zuo; Zhibin Fan; Junling Yue; Chunxia Zhang; Kezhen Yang; Jie Le
Source:
Journal of integrative plant biology 2022 v.64 no.1 pp. 56-72
ISSN:
1672-9072
Subject:
Arabidopsis thaliana; F-box proteins; alleles; cell division; direct contact; mutants; proteasome endopeptidase complex; transcription (genetics); ubiquitin-protein ligase; ubiquitination
Abstract:
... During the terminal stage of stomatal development, the R2R3‐MYB transcription factors FOUR LIPS (FLP/MYB124) and MYB88 limit guard mother cell division by repressing the transcript levels of multiple cell‐cycle genes. In Arabidopsis thaliana possessing the weak allele flp‐1, an extra guard mother cell division results in two stomata having direct contact. Here, we identified an ethylmethane sulfon ...
DOI:
10.1111/jipb.13193

2. AtHAD1, A haloacid dehalogenase-like phosphatase, is involved in repressing the ABA response

Author:
Sooji Lee; Eunsil Choi; Taekyung Kim; Jihwan Hwang; Jae-Hoon Lee
Source:
Biochemical and biophysical research communications 2022 v.587 pp. 119-125
ISSN:
0006-291X
Subject:
Arabidopsis; F-box proteins; abscisic acid; cytoplasm; drought; drought tolerance; genes; growth retardation; loss-of-function mutation; phosphates; research; seed germination; seedling growth; stomatal movement; survival rate; water stress
Abstract:
... Abscisic acid (ABA) plays an important role in seed germination, stomatal closure, and seedling growth inhibition in plants. Among downstream genes whose expression levels are regulated by AFA1 (Arabidopsis F-box Protein Hypersensitive to ABA 1), one gene, AtHAD1 upregulated by ABA was selected from Arabidopsis. AtHAD1 was induced by drought and salt stresses as well as by ABA and was found in dry ...
DOI:
10.1016/j.bbrc.2021.11.095

3. A Bursaphelenchus xylophilus pathogenic protein Bx‐FAR‐1, as potential control target, mediates the jasmonic acid pathway in pines

Author:
Tong‐Yue Wen; Xiao‐Qin Wu; Jian‐Ren Ye; Yi‐Jun Qiu; Lin Rui; Yan Zhang
Source:
Pest management science 2022 v.78 no.5 pp. 1870-1880
ISSN:
1526-498X
Subject:
Bursaphelenchus xylophilus; F-box proteins; Nicotiana benthamiana; Pinus thunbergii; disease control; double-stranded RNA; fatty acids; forest diseases; immune system; immunosuppression; jasmonic acid; ligands; parasitism; pathogenesis; pathogenicity; peptides; pest management; polyclonal antibodies; precipitin tests; two hybrid system techniques; vascular wilt; vitamin A
Abstract:
... BACKGROUND: The pine wilt disease (PWD) caused by Bursaphelenchus xylophilus is a devastating forest disease and its pathogenesis remains unclear. Secreted enzymes and proteins are important pathogenicity determinants and Bx‐FAR‐1 is an important pathogenic protein involved in the interaction between pine and B. xylophilus. However, the function of the Bx‐FAR‐1 protein in monitoring and prevention ...
DOI:
10.1002/ps.6805

4. Characterization of BRASSINOSTEROID F-BOX Proteins BRFPs that Regulate BRASSINOSTEROID-INSENSITIVE 2 Kinase

Author:
Yu Jeong Jeong; June Seung Lee; Dong-Gwan Kim
Source:
Journal of plant biology 2022 v.65 no.1 pp. 53-63
ISSN:
1226-9239
Subject:
F-box proteins; brassinosteroids; growth and development; phenotype; plant growth
Abstract:
... BRASSINOSTEROIDS (BRs) play important roles in regulating plant growth and development. The Arabidopsis GSK3-like kinase BIN2, a major negative regulator of BR signaling, plays diverse roles in plant growth and developmental processes. In a previous study, based on the relationship between BIN2 and its substrate, we reported the possibility that BIN2 protein stability is controlled by BRASSINOSTER ...
DOI:
10.1007/s12374-021-09335-0

5. Codonopsis lanceolata ameliorates sarcopenic obesity via recovering PI3K/Akt pathway and lipid metabolism in skeletal muscle

Author:
Min Ji Han; Se-Young Choung
Source:
Phytomedicine 2022 v.96 pp. 153877
ISSN:
0944-7113
Subject:
Codonopsis lanceolata; F-box proteins; Western blotting; adipocytes; anti-obesity effects; beta oxidation; blood lipids; epididymis; gene expression; high fat diet; high performance liquid chromatography; histology; insulin; ionization; muscle fibers; muscle protein; muscle strength; muscles; myotubes; non-specific serine/threonine protein kinase; obesity; palmitic acid; phosphatidylinositol 3-kinase; phosphorylation; protein degradation; protein synthesis; quantitative polymerase chain reaction; ribosomal proteins; sarcopenia; skeletal muscle; spectroscopy; therapeutics; triacylglycerols
Abstract:
... The incidence of sarcopenic obesity, muscle atrophy induced by obesity, has steadily increased and is emerging as a health problem. Although the anti-obesity effect of Codonopsis lanceolata (CL) is known, its efficacy against sarcopenic obesity has not been studied.We aimed to investigate the effect of CL on sarcopenic obesity and the changes in the related mechanisms to confirm the potential of C ...
DOI:
10.1016/j.phymed.2021.153877

6. Codonopsis lanceolata and its active component Tangshenoside I ameliorate skeletal muscle atrophy via regulating the PI3K/Akt and SIRT1/PGC-1α pathways

Author:
Tae-Young Kim; Keun-Tae Park; Se-Young Choung
Source:
Phytomedicine 2022 v.100 pp. 154058
ISSN:
0944-7113
Subject:
Codonopsis lanceolata; F-box proteins; Western blotting; biogenesis; dexamethasone; experimental design; malnutrition; medicinal plants; mitochondria; muscle fibers; muscle protein; muscle strength; muscles; muscular atrophy; myotubes; peroxisome proliferator-activated receptor gamma; phosphatidylinositol 3-kinase; protein degradation; protein synthesis; rapamycin; skeletal muscle
Abstract:
... Background: Skeletal muscle atrophy is caused by aging, disuse, malnutrition, and several diseases. However, there are still no effective drugs or treatments for muscle atrophy. Codonopsis lanceolata (CL), a traditional medicinal plant and food, has been reported to have anti-oxidative, anti-inflammatory, anti-tumor, and anti-obesity effects. Purpose: This study aimed to investigate the efficacy a ...
DOI:
10.1016/j.phymed.2022.154058

7. Comparative DNA Methylome of Phytoplasma Associated Retrograde Metamorphosis in Sesame (Sesamum indicum L.)

Author:
Pratima Verma; Amrita Singh; Supriya Purru; Kangila Venkataramana Bhat; Suman Lakhanpaul
Source:
Biology 2022 v.11 no.7 pp. -
ISSN:
2079-7737
Subject:
DNA methylation; DNA-binding proteins; F-box proteins; Phytoplasma; Sesamum indicum; bisulfites; cotyledons; cryptochromes; cytosine; genomics; hypocotyls; leaf area; leaves; loci; metamorphosis; methyltransferases; phyllody; phytoplasmal diseases; quantitative analysis; quantitative polymerase chain reaction; turgor
Abstract:
... Phytoplasma-associated diseases such as phyllody and little leaf are critical threats to sesame cultivation worldwide. The mechanism of the dramatic conversion of flowers to leafy structures leading to yield losses and the drastic reduction in leaf size due to Phytoplasma infection remains yet to be identified. Cytosine methylation profiles of healthy and infected sesame plants studied using Whole ...
DOI:
10.3390/biology11070954

8. Comparative transcriptomics of drought stress response of taproot meristem region of contrasting purple carrot breeding lines supported by physio-biochemical parameters

Author:
Zahide Neslihan Öztürk Gökçe; Ali Fuat Gökçe; Muhammad Daniyal Junaid; Usman Khalid Chaudhry
Source:
Functional & integrative genomics 2022 v.22 no.4 pp. 697-710
ISSN:
1438-793X
Subject:
F-box proteins; carrots; disease resistance; drought; drought tolerance; genes; genomics; geraniol; meristems; oxidoreductases; sequence analysis; stress response; tap roots; transcription factors; transcriptome; transcriptomics; water stress
Abstract:
... Carrot is one of the nutritious vegetable crops sensitive to drought stress resulting in loss of quality and yield. There are a lot of studies on detailed molecular mechanisms of drought stress response of main crops; however, very little information available on vegetables, including carrots. Hence, in this study, we investigated root transcriptome profiles from the meristematic region of two con ...
DOI:
10.1007/s10142-022-00868-2

9. Dual Role of Strigolactone Receptor Signaling Partner in Inhibiting Substrate Hydrolysis

Author:
Briana L. Sobecks; Jiming Chen; Diwakar Shukla
Source:
Journal of physical chemistry 2022 v.126 no.11 pp. 2188-2195
ISSN:
1520-5207
Subject:
F-box proteins; Oryza sativa; active sites; hydrolysis; ligands; metabolism; molecular dynamics; root growth; strigolactones
Abstract:
... Plant branch and root growth relies on metabolism of the strigolactone (SL) hormone. The interaction between the SL molecule, Oryza sativa DWARF14 (D14) SL receptor, and D3 F-box protein has been shown to play a critical role in SL perception. Previously, it was believed that D3 only interacts with the closed form of D14 to induce downstream signaling, but recent experiments indicate that D3, as w ...
DOI:
10.1021/acs.jpcb.1c10663

10. Eicosapentaenoic acid suppresses cisplatin-induced muscle atrophy by attenuating the up-regulated gene expression of ubiquitin

Author:
Yohei Ikeno; Maya Inomata; Yuka Tsukimura; Yuta Suzuki; Hiroto Takeuchi; Yui Harada; Risako Kon; Nobutomo Ikarashi; Yoshihiko Chiba; Takeshi Yamada; Junzo Kamei; Hiroyasu Sakai
Source:
Journal of nutritional biochemistry 2022 v.103 pp. 108953
ISSN:
0955-2863
Subject:
F-box proteins; RING finger domains; cisplatin; eicosapentaenoic acid; gene expression; mice; muscles; muscular atrophy; proteasome endopeptidase complex; skeletal muscle; ubiquitin; weight loss
Abstract:
... Previously it was shown that cisplatin causes muscle atrophy. Under this condition, cisplatin increased the expression of atorogenes, such as muscle ring finger 1 and atrogin-1 (also known as muscle atrophy F-box protein), in mouse skeletal muscle. It was reported recently that ubiquitin (Ub) and ubiquitinated protein levels in skeletal muscle were also up-regulated in cisplatin-induced muscle atr ...
DOI:
10.1016/j.jnutbio.2022.108953

11. The F-box E3 ubiquitin ligase AtSDR is involved in salt and drought stress responses in Arabidopsis

Author:
Bo Wen Li; Shuai Gao; Zhi Min Yang; Jian Bo Song
Source:
Gene 2022 v.809 pp. 146011
ISSN:
0378-1119
Subject:
Arabidopsis; F-box proteins; drought; drought tolerance; genes; heat; phenotype; plant development; salt stress; salt tolerance; ubiquitin-protein ligase; water stress
Abstract:
... F-box protein genes have been shown to play vital roles in plant development and stress respones. In Arabidopsis, there are more than 600 F-box proteins, and most of their functions are unclear. The present study shows that the F-box (SKP1-Cullin/CDC53-F-box) gene At5g15710 (Salt and Drought Responsiveness, SDR) is involved in abiotic stress responses in Arabidopsis. SDR is expressed in all tissue ...
DOI:
10.1016/j.gene.2021.146011

12. F-box only protein 9 and its role in cancer

Author:
Shujaat Hussain; Jianshu Dong; Xinli Ma; Jian Li; Shen Chen; Agboybor Clement; Hongmin Liu
Source:
Molecular biology reports 2022 v.49 no.2 pp. 1537-1544
ISSN:
0301-4851
Subject:
F-box proteins; apoptosis; carcinogenesis; cell cycle; cell proliferation; humans; metastasis; molecular biology; oncogenes; proteolysis; ubiquitin-protein ligase
Abstract:
... The F-box proteins (FBP), substrate recognition subunit of the SCF (Skp1-Cullin1-F-box protein complex) E3 ligase, play important roles in the ubiquitylation and subsequent degradation of the target proteins from several cellular processes. Disorders of F-box protein-mediated proteolysis lead to human malignancies. FBP plays an important role in many cellular processes, including cell proliferatio ...
DOI:
10.1007/s11033-021-07057-7

13. F-box protein FBXO41 suppresses breast cancer growth by inducing autophagic cell death through facilitating proteasomal degradation of oncogene SKP2

Author:
Yashika Agrawal; Tanisha Sharma; Sehbanul Islam; Kaustubh S. Nadkarni; Manas Kumar Santra
Source:
international journal of biochemistry & cell biology 2022 v.147 pp. 106228
ISSN:
1357-2725
Subject:
F-box proteins; autophagy; breast neoplasms; cell cycle checkpoints; cell proliferation; neoplasm cells; neoplasm progression; oncogenes; pro-apoptotic proteins; stress response; therapeutics; ubiquitin-protein ligase
Abstract:
... F-box proteins form SCF (Cullin1, SKP1 and F-box-protein) ubiquitin ligase complexes to ubiquitinate cellular proteins. They play key role in several biological processes, including cell cycle progression, cellular signaling, stress response and cell death pathways. Therefore, deregulation of F-box proteins is closely associated with cancer progression. However, the role of most of the F-box prote ...
DOI:
10.1016/j.biocel.2022.106228

14. An F-box protein from wheat, TaFBA-2A, negatively regulates JA biosynthesis and confers improved salt tolerance and increased JA responsiveness to transgenic rice plants

Author:
Liting Gao; Shuzhen Jia; Lu Cao; Yingjuan Ma; Junling Wang; Di Lan; Guangyan Guo; Jianfang Chai; Caili Bi
Source:
Plant physiology and biochemistry 2022 v.182 pp. 227-239
ISSN:
0981-9428
Subject:
F-box proteins; Triticum aestivum; biosynthesis; genes; jasmonic acid; plant growth; proteasome endopeptidase complex; rice; salt stress; salt tolerance; soil salinity; ubiquitin-protein ligase; wheat
Abstract:
... Soil salinity is a serious problem encountered by agriculture worldwide, which will lead to many harmful effects on plant growth, development, and even crop yield. F-box protein is the core subunit of the Skp1-Cullin-F-box (SCF) complex E3 ligase and plays crucial roles in regulating the growth, development, biotic & abiotic stresses, as well as hormone signaling pathway in plants. In this study, ...
DOI:
10.1016/j.plaphy.2022.04.025

15. FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation

Author:
Tao Zhou; Tingting Chen; Bin Lai; Wenfeng Zhang; Xi Luo; Ding Xia; Weihua Fu; Jie Xu
Source:
Cellular and molecular life sciences 2022 v.79 no.5 pp. 268
ISSN:
1420-682X
Subject:
F-box proteins; cell proliferation; epidermal growth factor receptors; half life; lung neoplasms; metastasis; mutants; prostatic neoplasms; protein content; ubiquitin-protein ligase; ubiquitination
Abstract:
... FBXW2 is a poorly characterized F-box protein, as a tumor suppressor that inhibits growth and metastasis of lung cancer by promoting ubiquitylation and degradation of oncogenic proteins, including SKP2 and β-catenin. However, what the biological functions of FBXW2 in prostate cancer cells and whether FBXW2 targets other substrates to involve in progression of prostate cancer is still unclear. Here ...
DOI:
10.1007/s00018-022-04320-3

16. An F‐box protein ACOZ1 functions in crossover formation by ensuring proper chromosome compaction during maize meiosis

Author:
Juli Jing; Nan Wu; Wanyue Xu; Yingxiang Wang; Wojciech P. Pawlowski; Yan He
Source:
The new phytologist 2022 v.235 no.1 pp. 157-172
ISSN:
0028-646X
Subject:
F-box proteins; chromatin; chromosome segregation; corn; genetic variation; ligases; mutants; synaptonemal complex; telomeres; ubiquitin
Abstract:
... Meiosis is an essential reproductive process to create new genetic variation. During early meiosis, higher order chromosome organization creates a platform for meiotic processes to ensure the accuracy of recombination and chromosome segregation. However, little is known about the regulatory mechanisms underlying dynamic chromosome organization in plant meiosis. Here, we describe abnormal chromosom ...
DOI:
10.1111/nph.18116

17. Genome-wide association study of the candidate genes for grape berry shape-related traits

Author:
Chuan Zhang; Liwen Cui; Jinggui Fang
Source:
BMC plant biology 2022 v.22 no.1 pp. 42
ISSN:
1471-2229
Subject:
F-box proteins; GATA transcription factors; RING finger domains; domestication; fruit morphology; fruits; genome-wide association study; grapes; horticulture; single nucleotide polymorphism; tomatoes; transcription initiation; ubiquitin-protein ligase
Abstract:
... BACKGROUND: In the breeding of new horticultural crops, fruit shape is an important selection characteristic. A variety of fruit shapes appeared during the gradual process of selection and domestication. However, few studies have been conducted on grape berry shape, especially studies related to mining candidate genes. To discover candidate genes related to grape berry shape, the present study fir ...
DOI:
10.1186/s12870-022-03434-x

18. Gosha-jinki-Gan (GJG) shows anti-aging effects through suppression of TNF-α production by Chikusetsusaponin V

Author:
Keisuke Hagihara; Kazuto Nunomura; Bangzhong Lin; Megumi Fumimoto; Junko Watanabe; Yasuharu Mizuhara
Source:
Gene 2022 v.815 pp. 146178
ISSN:
0378-1119
Subject:
F-box proteins; Oriental traditional medicine; bark; blood serum; central nervous system; cinnamon; dementia; genes; herbal medicines; horses; muscles; pain; permeability; quantitative polymerase chain reaction; sarcopenia; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Frailty develops due to multiple factors, such as sarcopenia, chronic pain, and dementia. Go-sha-jinki-Gan (GJG) is a traditional Japanese herbal medicine used for age-related symptoms. We have reported that GJG improved sarcopenia, chronic pain, and central nervous system function through suppression of tumor necrosis factor-alpha (TNF-α) production. In the present study, GJG was found to reduce ...
DOI:
10.1016/j.gene.2021.146178

19. High glucose induces apoptosis, glycogen accumulation and suppresses protein synthesis in muscle cells of olive flounder Paralichthys olivaceus

Author:
Jiahuan Liu; Mingzhu Pan; Dong Huang; Jing Wu; Yue Liu; Yanlin Guo; Wenbing Zhang; Kangsen Mai
Source:
British journal of nutrition 2022 v.127 no.11 pp. 1601-1612
ISSN:
1475-2662
Subject:
AMP-activated protein kinase; F-box proteins; Paralichthys olivaceus; RING finger domains; apoptosis; cytochrome c; glucose; glycogen; glycogen (starch) synthase; mammals; mannitol; membrane potential; mitochondrial membrane; muscles; muscular atrophy; nutrition; phosphorylase; protein synthesis; rapamycin; reactive oxygen species; ubiquitin-protein ligase
Abstract:
... The effect and the mechanism of high glucose on fish muscle cells are not fully understood. In the present study, muscle cells of olive flounder (Paralichthys olivaceus) were treated with high glucose (33 mM) in vitro. Cells were incubated in three kinds of medium containing 5 mM glucose, 5 mM glucose and 28 mM mannitol (as an isotonic contrast) or 33 mM glucose named the Control group, the Mannit ...
DOI:
10.1017/S0007114521002634

20. Identification of QTLs Controlling Resistance to Anthracnose Disease in Water Yam (Dioscorea alata)

Author:
Paterne Angelot Agre; Kwabena Darkwa; Bunmi Olasanmi; Olufisayo Kolade; Pierre Mournet; Ranjana Bhattacharjee; Antonio Lopez-Montes; David De Koeyer; Patrick Adebola; Lava Kumar; Robert Asiedu; Asrat Asfaw
Source:
Genes 2022 v.13 no.2 pp. -
ISSN:
2073-4425
Subject:
Dioscorea alata; F-box proteins; Glomerella cingulata; anthracnose; carboxylic ester hydrolases; chromosome mapping; chromosomes; cultivars; disease resistance; fungi; marker-assisted selection; phenotypic variation; protein kinases; quantitative traits; single nucleotide polymorphism; yams
Abstract:
... Anthracnose disease caused by a fungus Colletotrichum gloeosporioides is the primary cause of yield loss in water yam (Dioscorea alata), the widely cultivated species of yam. Resistance to yam anthracnose disease (YAD) is a prime target in breeding initiatives to develop durable-resistant cultivars for sustainable management of the disease in water yam cultivation. This study aimed at tagging quan ...
DOI:
10.3390/genes13020347

21. Lactobacillus plantarum WCFS1 alleviates Aeromonas hydrophila NJ-1-induced inflammation and muscle loss in zebrafish (Danio rerio)

Author:
Senlin Li; Lina Guo; Xuemeng Si; Zhaolai Dai; Zhigang Zhou; Zhenlong Wu
Source:
Aquaculture 2022 v.548 pp. 737603
ISSN:
0044-8486
Subject:
Aeromonas hydrophila; Danio rerio; F-box proteins; Lactobacillus plantarum; aquaculture; autophagy; dietary supplements; fish; freshwater; gene expression; genes; histology; inflammation; intestines; liver; mortality; muscles; myogenin; myostatin; necrosis; neoplasms
Abstract:
... Lactobacillus plantarum is known beneficial for the fish to defend against Aeromonas hydrophila infection which causes major disease outbreaks and severe economic losses for aquaculture. However, the mechanisms remain unclear. In the present study, 240 zebrafish with an average body weights of 0.33 ± 0.01 g were randomly divided into 4 groups. The zebrafish were fed a basal diet supplemented with ...
DOI:
10.1016/j.aquaculture.2021.737603

22. Lotus japonicus HAR1 regulates root morphology locally and systemically under a moderate nitrate condition in the absence of rhizobia

Author:
Mika Hayashi-Tsugane; Masayoshi Kawaguchi
Source:
Planta 2022 v.255 no.5 pp. 95
ISSN:
0032-0935
Subject:
F-box proteins; Lotus corniculatus var. japonicus; autoregulation; lateral roots; loss-of-function mutation; mutants; nitrates; nitrogen; nodulation; phenotype; root growth; root systems; soil
Abstract:
... MAIN CONCLUSION: The local and long-distance signaling pathways mediated by the leucine-rich repeat receptor kinase HAR1 suppress root branching and promote primary root length in response to nitrate supply. The root morphology of higher plants changes plastically to effectively absorb nutrients and water from the soil. In particular, legumes develop root organ nodules, in which symbiotic rhizobia ...
DOI:
10.1007/s00425-022-03873-8

23. The MaC2H2-like zinc finger protein is involved in ripening and ripening disorders caused by chilling stress via the regulation of softening-related genes in ‘Fenjiao’ banana

Author:
Xiuhua Lai; Xiaoyang Zhu; Hangcong Chen; Xuequn Pang; Weixin Chen; Xueping Li; Zunyang Song
Source:
Postharvest biology and technology 2022 v.186 pp. 111817
ISSN:
0925-5214
Subject:
F-box proteins; bananas; biosynthesis; cell walls; cold stress; ethylene; ethylene production; fruit quality; fruits; genes; protein-protein interactions; starch; transcription (genetics); transcription factors; zinc finger motif
Abstract:
... As one of the largest transcription factor families, C2H2 zinc finger proteins contain a zinc finger motif and a conserved DNA-binding homeodomain. Although C2H2 zinc finger proteins have been found to play an essential role in ethylene biosynthetic and cold stress in banana fruit, their transcriptional regulatory mechanisms involved in the softening of ‘Fenjiao’ banana remain largely elusive. In ...
DOI:
10.1016/j.postharvbio.2021.111817

24. Molecular characterization of wheat floret development‐related F‐box protein (TaF‐box2): Possible involvement in regulation of Arabidopsis flowering

Author:
Jae Ho Kim; Woo Joo Jung; Moon Seok Kim; Chan Seop Ko; Jin Seok Yoon; Min Jeong Hong; Hyo Jeong Shin; Yong Weon Seo
Source:
Physiologia plantarum 2022 v.174 no.2 pp. e13677
ISSN:
0031-9317
Subject:
Arabidopsis; F-box proteins; Triticum aestivum; cytoplasm; florets; fluorescence; grain yield; hypocotyls; plasma membrane; proteasome endopeptidase complex; tobacco; two hybrid system techniques; ubiquitin-protein ligase; ubiquitination; wheat
Abstract:
... In wheat (Triticum aestivum L.), the floret development stage is an important step in determining grain yield per spike; however, the molecular mechanisms underlying floret development remain unclear. In this study, we elucidated the role of TaF‐box2, a member of the F‐box‐containing E3 ubiquitin protein ligases, which is involved in floret development and anthesis of wheat. TaF‐box2 was transient ...
DOI:
10.1111/ppl.13677

25. Nanopore sequencing data and structural variants identified in Prunus avium seedlings derived through mutagenesis

Author:
Per McCord; Seanna Hewitt; Amit Dhingra
Source:
Data in Brief 2022 v.43 pp. 108384
ISSN:
2352-3409
Subject:
DNA; F-box proteins; Prunus avium; cysteine; cytochrome P-450; females; genes; mutagenesis; nanopores; phenotype; phosphoenolpyruvate carboxylase; proteinases; ubiquitin-protein ligase
Abstract:
... DNA from four sweet cherry seedlings derived from gamma-irradiated female parents was sequenced via nanopore technology (Oxford Nanopore MinION). Total data yield was 8.07 Gb, ranging from 0.92 to 3.36 Gb per sample, with the average length of mapped reads ranging from 22 Kbp–24 Kbp. Sequence data was then analysed to identify and characterize variants using a published sweet cherry reference geno ...
DOI:
10.1016/j.dib.2022.108384

26. Nitric oxide negatively regulates gibberellin signaling to coordinate growth and salt tolerance in Arabidopsis

Author:
Lichao Chen; Shuhao Sun; Chun-Peng Song; Jian-Min Zhou; Jiayang Li; Jianru Zuo
Source:
Journal of genetics and genomics 2022 v.49 no.8 pp. 756-765
ISSN:
1673-8527
Subject:
Arabidopsis; F-box proteins; S-nitrosylation; genomics; gibberellins; nitric oxide; plant hormones; post-translational modification; salinity; salt tolerance; stress tolerance
Abstract:
... In response to dynamically altered environments, plants must finely coordinate the balance between growth and stress responses for their survival. However, the underpinning regulatory mechanisms remain largely elusive. The phytohormone gibberellin promotes growth via a derepression mechanism by proteasomal degradation of the DELLA transcription repressors. Conversely, the stress-induced burst of n ...
DOI:
10.1016/j.jgg.2022.02.023

27. Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients

Author:
Taishi Kondo; Tomoaki Ishida; Ke Ye; Marin Muraguchi; Yohei Tanimura; Masato Yoshida; Kan’ichiro Ishiuchi; Tomoki Abe; Takeshi Nikawa; Keisuke Hagihara; Hidetoshi Hayashi; Toshiaki Makino
Source:
Natural medicines 2022 v.76 no.3 pp. 594-604
ISSN:
1340-3443
Subject:
Aconitum carmichaelii; F-box proteins; Oriental traditional medicine; RING finger domains; apoptosis; aqueous solutions; autoclaving; drugs; gene expression; kidneys; mice; muscles; muscular atrophy; myoblasts; quality control; transaminases
Abstract:
... Processed aconite root (PA), the tuberous root of Aconitum carmichaelii prepared by autoclaving, is a crude drug used in Japanese traditional Kampo medicine and traditional Chinese medicine for the symptoms of kidney deficiency, that is related to the muscle atrophy in modern medicine. The objective of the present study is to evaluate the effectiveness of PA on muscle atrophy and to find its activ ...
DOI:
10.1007/s11418-022-01606-5

28. Taurine alleviates endoplasmic reticulum stress, inflammatory cytokine expression and mitochondrial oxidative stress induced by high glucose in the muscle cells of olive flounder (Paralichthysolivaceus)

Author:
Jiahuan Liu; Mingzhu Pan; Yue Liu; Dong Huang; Kai Luo; Zhenhua Wu; Wenbing Zhang; Kangsen Mai
Source:
Fish & shellfish immunology 2022 v.123 pp. 358-368
ISSN:
1050-4648
Subject:
F-box proteins; Paralichthys olivaceus; RING finger domains; apoptosis; cytochrome c; endoplasmic reticulum; endoplasmic reticulum stress; gene expression; glucose; glutathione; inflammation; interleukin-6; interleukin-8; malondialdehyde; mitochondria; muscles; muscular atrophy; necrosis; neoplasms; oxidation; oxidative stress; reactive oxygen species; shellfish; superoxide dismutase; taurine
Abstract:
... The aim of the present study was to evaluate the effects of taurine on endoplasmic reticulum stress, inflammatory cytokine expression and mitochondrial oxidative stress induced by high glucose in primary cultured muscle cells of olive flounder (Paralichthys olivaceus). Three experimental groups were designed as follows: muscle cells of olive flounder incubated with three kinds of medium containing ...
DOI:
10.1016/j.fsi.2022.03.021

29. ZmCOI2a and ZmCOI2b redundantly regulate anther dehiscence and gametophytic male fertility in maize

Author:
Xiaolong Qi; Shuwei Guo; Dong Wang; Yu Zhong; Ming Chen; Chen Chen; Dehe Cheng; Zongkai Liu; Tai An; Jinlong Li; Yanyan Jiao; Yuwen Wang; Jinchu Liu; Yuling Zhang; Shaojiang Chen; Chenxu Liu
Source:
plant journal 2022 v.110 no.3 pp. 849-862
ISSN:
0960-7412
Subject:
Arabidopsis; CRISPR-Cas systems; F-box proteins; Zea mays; corn; dehiscence; gametophytes; jasmonic acid; male fertility; male sterility; males; mutants; mutation; pollen; pollen germination; pollen viability; seed development; transcriptomics; two hybrid system techniques
Abstract:
... In higher plants, the generation and release of viable pollen from anthers is vital for double fertilization and the initiation of seed development. Thus, the characterization of genes related to pollen development and anther dehiscence in plants is of great significance. The F‐box protein COI1 plays a crucial role in the jasmonate (JA) signaling pathway and interacts with many JAZ family proteins ...
DOI:
10.1111/tpj.15708

30. The proteome reveals the involvement of serine/threonine kinase in the recognition of self- incompatibility in almond

Author:
Yeting XU; Qiuping ZHANG; Xiao ZHANG; Jian WANG; Mubarek AYUP; Bo YANG; Chunmiao GUO; Peng GONG; Wenxuan DONG
Source:
Journal of proteomics 2022 v.256 pp. 104505
ISSN:
1874-3919
Subject:
F-box proteins; RNA; almonds; autophagy; bioinformatics; cultivars; fluorescence microscopy; gametophytes; haplotypes; homologous recombination; loci; oxidative phosphorylation; pistil; pollen; pollen tubes; protein synthesis; proteome; proteomics; ribonucleases; serine; threonine
Abstract:
... The self-incompatibility recognition mechanism determines whether the gametophyte is successfully fertilized between pollen tube SCF (SKP1–CUL1–F-box-RBX1) protein and pistil S-RNase protein during fertilization is unclear. In this study, the pistils of two almond cultivars ‘Wanfeng’ and ‘Nonpareil’ were used as the experimental materials after self- and nonself/cross-pollination, and pistils from ...
DOI:
10.1016/j.jprot.2022.104505

31. A putative F‐box‐domain‐encoding gene AOL_s00076g207 regulates the development and pathogenicity of Arthrobotrys oligospora

Author:
Hui Peng; Xinyuan Dong; Hengqian Lu; Xiaowei Kong; Xiangdong Zha; Yongzhong Wang
Source:
Journal of basic microbiology 2022 v.62 no.1 pp. 74-81
ISSN:
0233-111X
Subject:
Arthrobotrys oligospora; F-box proteins; Nematoda; biological control; conidia; fungi; genes; germination; mutants; mycelium; pathogenicity; predation; ubiquitin; ubiquitin-protein ligase
Abstract:
... F‐box protein is a key component of the Skp1‐cullin‐F‐box‐type ubiquitin ligase complex (SCF‐ULC) that marks its target proteins with ubiquitin for proteasomal degradation. In this study, we explored the potential role of AOL_s00076g207 (Aog207) in Arthrobotrys oligospora, a model fungus for studying nematodes‐fungi interactions. The Aog207 gene encodes a putative F‐box protein of the SCF‐ULC. Del ...
DOI:
10.1002/jobm.202100388

32. The rice EP3 and OsFBK1 E3 ligases alter plant architecture and flower development, and affect transcript accumulation of microRNA pathway genes and their targets

Author:
Rita S. Borna; Erik H. Murchie; Kevin A. Pyke; Jeremy A. Roberts; Zinnia H. Gonzalez‐Carranza
Source:
Plant biotechnology journal 2022 v.20 no.2 pp. 297-309
ISSN:
1467-7644
Subject:
Arabidopsis; F-box proteins; Oryza sativa; biotechnology; flower morphology; flowering; flowers; gain-of-function mutation; ligases; microRNA; panicles; plant architecture; pollen viability; rice; sequence analysis
Abstract:
... ERECTA PANICLE 3 (EP3) and ORYZA SATIVA F‐BOX KELCH 1 (OsFBK1) proteins share 57% and 54% sequence identity with the Arabidopsis F‐box protein HAWAIIAN SKIRT (HWS). Previously we showed that EP3 is a functional orthologue of HWS. Here we demonstrate that OsFBK1 is another functional orthologue of HWS and show the complexity of interaction between EP3 and OsFBK1 genes at different developmental sta ...
DOI:
10.1111/pbi.13710

33. The strigolactone receptor D14 targets SMAX1 for degradation in response to GR24 treatment and osmotic stress

Author:
Qingtian Li; Elena Sánchez Martín-Fontecha; Aashima Khosla; Alexandra R.F. White; Sunhyun Chang; Pilar Cubas; David C. Nelson
Source:
Plant communications 2022 v.3 no.2 pp. 100303
ISSN:
2590-3462
Subject:
Arabidopsis thaliana; F-box proteins; biosynthesis; evolution; genetic analysis; karrikins; models; osmotic stress; strigolactones
Abstract:
... The effects of the phytohormone strigolactone (SL) and smoke-derived karrikins (KARs) on plants are generally distinct, despite the fact that they are perceived through very similar mechanisms. The homologous receptors DWARF14 (D14) and KARRIKIN-INSENSITIVE2 (KAI2), together with the F-box protein MORE AXILLARY GROWTH2 (MAX2), mediate SL and KAR responses, respectively, by targeting different SMAX ...
DOI:
10.1016/j.xplc.2022.100303

34. Arabidopsis F-box protein At1g08710 interacts with transcriptional protein ADA2b and imparts drought stress tolerance by negatively regulating seedling growth

Author:
Venkateswara Rao; Vijaybhaskar Virupapuram
Source:
Biochemical and biophysical research communications 2021 v.536 pp. 45-51
ISSN:
0006-291X
Subject:
Arabidopsis thaliana; F-box proteins; drought; drought tolerance; malondialdehyde; messenger RNA; mutants; protein subunits; research; seedling growth; transcription (genetics); ubiquitin-protein ligase; water stress
Abstract:
... Plants experience abiotic stresses throughout their life cycle and accordingly respond to tide over the unfavorable conditions. Plants adopt to drought stress through various molecular, biochemical, physiological and cellular processes. F-box protein subunit of the Skp1-Cullin-F-box (SCF) E3 ubiquitin ligases plays crucial role in imparting specificity for selective degradation of target proteins. ...
DOI:
10.1016/j.bbrc.2020.12.054

35. Arsenic Stress-Related F-Box (ASRF) gene regulates arsenic stress tolerance in Arabidopsis thaliana

Author:
Yadira Peña-Garcia; Suhas Shinde; Purushothaman Natarajan; Carlos Lopez-Ortiz; Nagamani Balagurusamy; Ana Cristina Delgado Chavez; Thangasamy Saminathan; Padma Nimmakayala; Umesh K. Reddy
Source:
Journal of hazardous materials 2021 v.407 pp. 124831
ISSN:
0304-3894
Subject:
Arabidopsis thaliana; F-box proteins; arsenates; arsenic; genes; genome-wide association study; heterozygosity; homeostasis; homozygosity; loci; mutants; oxidative stress; phosphates; progeny; proline; reactive oxygen species; seedling growth; stress tolerance; toxicity; transcriptomics
Abstract:
... Arsenic (As), a non-biodegradable contaminant, is extremely toxic to plants and animals in its inorganic form. As negatively affects plant growth and development, primarily by inducing oxidative stress through redox imbalance. Here we characterized the Arabidopsis F-box protein gene AT2G16220 (Arsenic Stress-Related F-box (ASRF)) that we identified in the genome-wide association study. The asrf mu ...
DOI:
10.1016/j.jhazmat.2020.124831
CHORUS:
10.1016/j.jhazmat.2020.124831

36. Association Mapping of Verticillium Wilt Disease in a Worldwide Collection of Cotton (Gossypium hirsutum L.)

Author:
Adem Bardak; Sadettin Çelik; Oktay Erdoğan; Remzi Ekinci; Ziya Dumlupinar
Source:
Plants 2021 v.10 no.2 pp. -
ISSN:
2223-7747
Subject:
DNA-directed RNA polymerase; F-box proteins; Gossypium hirsutum; Verticillium dahliae; Verticillium wilt; abiotic stress; cotton; disease severity; endo-1,4-beta-glucanase; industry; isozymes; marker-assisted selection; metal tolerance; molybdates; pathotypes; pyruvate kinase; quantitative traits; raw materials; ribonucleases; single nucleotide polymorphism; transcription factors; ubiquitin-protein ligase
Abstract:
... Cotton (Gossypium spp.) is the best plant fiber source in the world and provides the raw material for industry. Verticillium wilt caused by Verticillium dahliae Kleb. is accepted as a major disease of cotton production. The most practical way to deal with verticillium wilt is to develop resistant/tolerant varieties after cultural practices. One of the effective selections in plant breeding is the ...
DOI:
10.3390/plants10020306

37. AtMIF1 increases seed oil content by attenuating GL2 inhibition

Author:
Tianhe Cheng; Peng Zhao; Yanru Ren; Jun Zou; Meng‐Xiang Sun
Source:
new phytologist 2021 v.229 no.4 pp. 2152-2162
ISSN:
0028-646X
Subject:
Arabidopsis thaliana; F-box proteins; cooking fats and oils; engineering; genes; lipid content; oil crops; plant breeding; plant growth; proteasome endopeptidase complex; protein degradation; raw materials; seed oils; seeds; transcriptional activation; transgenic plants; ubiquitin-protein ligase; vegetable oil
Abstract:
... Vegetable oil is a major edible oil and an important industrial raw material. However, breeders have found it challenging to improve the oil content of crop seeds, and little is known about regulators with the potential to increase oil content via molecular engineering in modern oil crop breeding. We reported an F‐box protein, Arabidopsis thaliana MYB Interaction Factor 1 (AtMIF1), which is a memb ...
DOI:
10.1111/nph.17016

38. The Biological Function and Roles in Phytohormone Signaling of the F-Box Protein in Plants

Author:
Keheng Xu; Nan Wu; Wenbo Yao; Xiaowei Li; Yonggang Zhou; Haiyan Li
Source:
Agronomy 2021 v.11 no.11 pp. -
ISSN:
2073-4395
Subject:
F-box proteins; agronomy; growth and development; peptides; plant hormones; protein degradation; ubiquitin-protein ligase; ubiquitination
Abstract:
... The ubiquitin–proteasome pathway (UPP) is an important protein degradation pathway that can participate in the regulation of the physiological process of organisms by specifically removing abnormal peptides and degrading cell regulators. UPP mainly involves three enzymes, among which the E3 ubiquitin ligase function is central to UPP. E3 ubiquitin ligases can recruit substrate protein for ubiquiti ...
DOI:
10.3390/agronomy11112360

39. Co-operative binding of SKP1, Cullin1 and Cullin7 to FBXW8 results in Cullin1-SKP1-FBXW8-Cullin7 functional complex formation that monitors cellular function of β-TrCP1

Author:
Sehbanul Islam; Parul Dutta; Kriti Chopra; Osheen Sahay; Srikanth Rapole; Radha Chauhan; Manas Kumar Santra
Source:
International journal of biological macromolecules 2021 v.190 pp. 233-243
ISSN:
0141-8130
Subject:
F-box proteins; cell movement; ubiquitin-protein ligase
Abstract:
... F-box protein FBXW8 is known to interact with scaffolding protein Cullin1 and Cullin7 to form SCF (SKP1, Cullin and F-box protein) complex. However, detail understanding about the importance of both Cullins for SCF-FBXW8 complex formation as well as its ubiquitin ligase activity remains elusive. Here, we show that, through in vitro and in vivo studies, Cullin1 and Cullin7 increase each other's bin ...
DOI:
10.1016/j.ijbiomac.2021.08.195

40. Comparative transcriptomic analysis reveals the regulatory mechanism of the gibberellic acid pathway of Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.) dwarf mutants

Author:
Zhaoxia Sun; Xinfang Wang; Ronghua Liu; Wei Du; Mingchuan Ma; Yuanhuai Han; Hongying Li; Longlong Liu; Siyu Hou
Source:
BMC plant biology 2021 v.21 no.1 pp. 206
ISSN:
1471-2229
Subject:
Arabidopsis; F-box proteins; Fagopyrum tataricum; amino acids; biosynthesis; buckwheat; crops; dwarfing; electrospray ionization mass spectrometry; ethyl methanesulfonate; gene expression regulation; genes; gibberellic acid; homozygosity; industry; jasmonic acid; mutants; phenotype; plant height; salicylic acid; sequence analysis; signal transduction; single nucleotide polymorphism; tandem mass spectrometry; transcriptomics
Abstract:
... BACKGROUND: Tartary buckwheat is an important minor crop species with high nutritional and medicinal value and is widely planted worldwide. Cultivated Tartary buckwheat plants are tall and have hollow stems that lodge easily, which severely affects their yield and hinders the development of the Tartary buckwheat industry. METHODS: Heifeng No. 1 seeds were treated with ethylmethanesulfonate (EMS) t ...
DOI:
10.1186/s12870-021-02978-8

41. Comprehensive transcriptome-based characterization of differentially expressed genes involved in carotenoid biosynthesis of different ripening stages of Capsicum

Author:
Quan-Hui Li; Shi-Peng Yang; Ya-Nan Yu; Abid Khan; Peng-Long Feng; Muhammad Ali; Deng-kui Shao; Ya-Yi Wang; Rui-Xing Zhang; Wen-Xian Gai; Rui Han; Xiao Ma; Quan-Gang Hou; Zhen-Hui Gong
Source:
Scientia horticulturae 2021 v.288 pp. 110311
ISSN:
0304-4238
Subject:
Capsicum annuum; F-box proteins; GATA transcription factors; biosynthesis; capsanthin; color; flavonoids; flowers; fruit color; fruiting; fruits; gene expression regulation; genes; hot peppers; lutein; pepper; phenylalanine; phenylpropanoids; transcriptome; zeaxanthin; zinc finger motif
Abstract:
... Pepper (Capsicum annuum L.) is one of the widely cultivated vegetable crops in the world. The color formation of pepper fruit is closely related to the carotenoid composition and content. In order to understand the regulatory mechanism of red and orange pepper formation, comprehensive transcriptome and carotenoid content determination were carried out at 25, 40 and 55 days after flower. At the mat ...
DOI:
10.1016/j.scienta.2021.110311

42. CsUFO is involved in the formation of flowers and tendrils in cucumber

Author:
Yue Chen; Haifan Wen; Jian Pan; Hui Du; Keyan Zhang; Leyu Zhang; Yao Yu; Huanle He; Run Cai; Junsong Pan; Gang Wang
Source:
Theoretical and applied genetics 2021 v.134 no.7 pp. 2141-2150
ISSN:
0040-5752
Subject:
Cucumis sativus; F-box proteins; cucumbers; ethyl methanesulfonate; exons; flowering; flowers; genetic analysis; mutagenesis; mutants; phenotype; single nucleotide polymorphism; transcriptomics
Abstract:
... KEY MESSAGE: An unusual flower and tendril (uft) mutant in cucumber was caused by a mutation in Csa1G056950 encoding an F-box protein. Flowers and tendrils are important agronomic and yield traits of cucumber (Cucumis sativus L.). In this study, we identified an unusual flower and tendril (uft) mutant from an ethyl methanesulfonate (EMS) mutagenesis population. Genetic analysis revealed that the p ...
DOI:
10.1007/s00122-021-03811-4

43. Current Understanding of the CRL1 Complex in Arabidopsis

Author:
Og-Geum Woo; Hani Kim; Jae-Hoon Lee
Source:
Journal of plant biology 2021 v.64 no.1 pp. 1-12
ISSN:
1226-9239
Subject:
Arabidopsis; F-box proteins; abiotic stress; amino acids; eukaryotic cells; knowledge; plant biology; receptors; stress response; substrate specificity; ubiquitin-protein ligase; ubiquitination
Abstract:
... Ubiquitination is a post-translational modification involved in diverse cellular processes in eukaryotes. Among three kinds of enzymes (E1, E2, and E3) involved in ubiquitination, the E3 ubiquitin ligase family possesses a large number of members (up to 1400) and serves as a major determinant for substrate specificity. As a type of E3 ligase, cullin-RING E3 ligase (CRL) forms multi-subunit complex ...
DOI:
10.1007/s12374-020-09274-2

44. Degradation of STOP1 mediated by the F‐box proteins RAH1 and RAE1 balances aluminum resistance and plant growth in Arabidopsis thaliana

Author:
Qiu Fang; Fanglin Zhou; Yang Zhang; Somesh Singh; Chao‐Feng Huang
Source:
plant journal 2021 v.106 no.2 pp. 493-506
ISSN:
0960-7412
Subject:
Arabidopsis thaliana; F-box proteins; aluminum; mutants; mutation; phenotype; plant growth; transcription factors; ubiquitination; zinc finger motif
Abstract:
... The C2H2‐type zinc finger transcription factor sensitive to proton rhizotoxicity 1 (STOP1) is crucial for aluminum (Al) resistance in Arabidopsis. The F‐box protein Regulation of AtALMT1 Expression 1 (RAE1) was recently reported to regulate the stability of STOP1. There is a unique homolog of RAE1, RAH1 (RAE1 homolog 1), in Arabidopsis, but the biological function of RAH1 is still not known. In th ...
DOI:
10.1111/tpj.15181

45. Design, synthesis and mode of action of novel 3‐chloro‐6‐pyrazolyl picolinate derivatives as herbicide candidates

Author:
Zhikun Yang; Qibo Li; Jiaming Yin; Ruiquan Liu; Hao Tian; Liusheng Duan; Zhaohu Li; Baomin Wang; Weiming Tan; Shangzhong Liu
Source:
Pest management science 2021 v.77 no.5 pp. 2252-2263
ISSN:
1526-498X
Subject:
Arabidopsis thaliana; F-box proteins; auxins; clopyralid; corn; herbicidal properties; mechanism of action; picloram; picolinic acid; wheat
Abstract:
... BACKGROUND: Picolinate/picolinic acid compounds are an important class of synthetic auxin herbicides. To explore the herbicidal activity of 6‐pyrazolyl picolinate compounds, a series of 3‐chloro‐6‐pyrazolyl‐picolinate derivatives was designed and synthesized. RESULTS: Twenty‐five 3‐chloro‐6‐pyrazolyl‐picolinate derivatives synthesized were tested for herbicidal activity and the IC₅₀ value of compo ...
DOI:
10.1002/ps.6250

46. The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway

Author:
Valentine Spagnol; Caio A.B. Oliveira; Suzanne J. Randle; Patrícia M.S. Passos; Camila R.S.T.B. Correia; Natália B. Simaroli; Joice S. Oliveira; Tycho E.T. Mevissen; Ana Carla Medeiros; Marcelo D. Gomes; David Komander; Heike Laman; Felipe Roberti Teixeira
Source:
Biochimica et biophysica acta 2021 v.1865 no.1 pp. 129754
ISSN:
0304-4165
Subject:
F-box proteins; alternative splicing; androgens; apoptosis; cycloheximide; estrogens; microscopy; precipitin tests; transcription (genetics); ubiquitin; ubiquitin-protein ligase; ubiquitination
Abstract:
... Ubiquitously eXpressed Transcript isoform 2 (UXTV2) is a prefoldin-like protein involved in NF-κB signaling, apoptosis, and the androgen and estrogen response. UXT-V2 is a cofactor in the NF-κB transcriptional enhanceosome, and its knockdown inhibits TNF-α -induced NF-κB activation. Fbxo7 is an F-box protein that interacts with SKP1, Cullin1 and RBX1 proteins to form an SCF(Fbxo7) E3 ubiquitin lig ...
DOI:
10.1016/j.bbagen.2020.129754

47. FBXW8 regulates G1 and S phases of cell cycle progression by restricting β‐TrCP1 function

Author:
Sehbanul Islam; Parul Dutta; Kriti Chopra; Srikanth Rapole; Radha Chauhan; Manas Kumar Santra
Source:
FEBS journal 2021 v.288 no.18 pp. 5474-5497
ISSN:
1742-464X
Subject:
DNA; F-box proteins; flow cytometry; fluorescent antibody technique; homeostasis; interphase
Abstract:
... Sequential alteration in the expression levels of cell cycle regulatory proteins is crucial for faithful cell cycle progression to maintain the cellular homeostasis. F‐box protein β‐TrCP1 is known to control the expression levels of several important cell cycle regulatory proteins. However, how the function of β‐TrCP1 is regulated in spatiotemporal manner during cell cycle progression remains elus ...
DOI:
10.1111/febs.15828

48. F‐box protein CFK1 interacts with and degrades de novo DNA methyltransferase in Arabidopsis

Author:
Jiani Chen; Jie Liu; Jianjun Jiang; Shuiming Qian; Jingwen Song; Rachel Kabara; Isabel Delo; Giovanna Serino; Fengquan Liu; Zhihua Hua; Xuehua Zhong
Source:
new phytologist 2021 v.229 no.6 pp. 3303-3317
ISSN:
0028-646X
Subject:
Arabidopsis thaliana; DNA methylation; DNA methyltransferase; F-box proteins; bisulfites; constitutive photomorphogenesis 9 signalosome; genes; homeostasis; loss-of-function mutation; proteasome endopeptidase complex; quality control; transcription (genetics); two hybrid system techniques; ubiquitin-protein ligase
Abstract:
... DNA methylation plays crucial roles in cellular development and stress responses through gene regulation and genome stability control. Precise regulation of DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2), the de novo Arabidopsis DNA methyltransferase, is crucial to maintain DNA methylation homeostasis to ensure genome integrity. Compared with the extensive studies on DRM2 targeting mechanisms, litt ...
DOI:
10.1111/nph.17103

49. High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae

Author:
Simei He; Xiao Dong; Guanghui Zhang; Wei Fan; Shengchang Duan; Hong Shi; Dawei Li; Rui Li; Geng Chen; Guangqiang Long; Yan Zhao; Mo Chen; Mi Yan; Jianli Yang; Yingchun Lu; Yanli Zhou; Wei Chen; Yang Dong; Shengchao Yang
Source:
Molecular ecology resources 2021 v.21 no.1 pp. 153-169
ISSN:
1755-098X
Subject:
Erigeron breviscapus; F-box proteins; Helianthus annuus; biosynthesis; breeding; chromosomes; ecology; flavonoids; flowering; genes; genome assembly; leaf development; leaf morphology; lettuce; medicinal plants; nucleotide sequences; serine; synthesis; yeasts
Abstract:
... Erigeron breviscapus is an important medicinal plant in Compositae and the first species to realize the whole process from the decoding of the draft genome sequence to scutellarin biosynthesis in yeast. However, the previous low‐quality genome assembly has hindered the optimization of candidate genes involved in scutellarin synthesis and the development of molecular‐assisted breeding based on the ...
DOI:
10.1111/1755-0998.13257

50. Loss‐of‐function of ARABIDOPSIS F‐BOX PROTEIN HYPERSENSITIVE TO ABA 1 enhances drought tolerance and delays germination

Author:
Hani Kim; Eunyoung Song; Yeojin Kim; Eunsil Choi; Jihwan Hwang; Jae‐Hoon Lee
Source:
Physiologia plantarum 2021 v.173 no.4 pp. 2376-2389
ISSN:
0031-9317
Subject:
Arabidopsis; F-box proteins; adults; drought; drought tolerance; epistasis; genes; loss-of-function mutation; microarray technology; phenotype; proteasome endopeptidase complex; seed germination; ubiquitin; ubiquitination
Abstract:
... ABA is a phytohormone involved in diverse plant events such as seed germination and drought response. An F‐box protein functions as a substrate receptor of the SCF complex and is responsible for ubiquitination of target proteins, triggering their subsequent degradation mediated by ubiquitin proteasome system. Here, we have isolated a gene named ARABIDOPSIS F‐BOX PROTEIN HYPERSENSITIVE TO ABA 1 (AF ...
DOI:
10.1111/ppl.13588