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1. Age-relevant renal effects of cadmium exposure through consumption of home-harvested rice in female Japanese farmers

Author:
Hyogo Horiguchi; Etsuko Oguma; Satoshi Sasaki; Hitomi Okubo; Kentaro Murakami; Kayoko Miyamoto; Yoko Hosoi; Katsuyuki Murata; Fujio Kayama
Source:
Environment international 2013 v.56 pp. 1-9
ISSN:
0160-4120
Subject:
blood; cadmium; creatinine; cross-sectional studies; dose response; elderly; farmers; females; kidney diseases; proteins; renal function; rice; risk; urine; women; Japan
Abstract:
... There are cadmium-polluted areas in Japan, where farmers may be at risk of renal dysfunction due to cadmium exposure through consumption of home-harvested rice. The aims of this study were to investigate levels of cadmium exposure and accumulation and their renal effects in female farmers residing in cadmium-polluted areas, and to consider the relevance of age to the effects of cadmium. We conduct ...
DOI:
10.1016/j.envint.2013.03.001

2. Age-specific plasma biochemistry reference ranges in <1 year old dogs in Japan

Author:
Sako, Toshinori; Mori, Akihiro; Lee, Peter; Igarashi, Ayano; Oda, Hitomi; Saeki, Kaori; Miki, Yohei; Kurishima, Miyuki; Mimura, Kana; Nozawa, Satoshi; Itabashi, Yukiko; Kiyosawa, Yoshio; Ishioka, Katsumi; Arai, Toshiro
Source:
Veterinary research communications 2011 v.35 no.4 pp. 201-209
ISSN:
0165-7380
Subject:
alanine transaminase; albumins; alkaline phosphatase; aspartate transaminase; blood; cholesterol; creatinine; dogs; gender; glucose; linear models; regression analysis; triacylglycerol lipase; urea nitrogen; veterinary clinics; Japan
Abstract:
... The purpose of this study was to investigate and propose possible reference intervals of plasma biochemical analytes in young dogs (<12 months old) in Japan, using 896 canine plasma samples, collected from an array of veterinary clinics throughout the greater Tokyo metropolis area in Japan. The following biochemical parameters were assessed: albumin (ALB), alanine aminotransferase (ALT), alkaline ...
DOI:
10.1007/s11259-011-9463-0
PubMed:
21331514

3. Application of the hybrid approach to the benchmark dose of urinary cadmium as the reference level for renal effects in cadmium polluted and non-polluted areas in Japan

Author:
Yasushi Suwazono; Kazuhiro Nogawa; Mirei Uetani; Satoru Nakada; Teruhiko Kido; Hideaki Nakagawa
Source:
Environmental research 2011 v.111 no.2 pp. 312-314
ISSN:
0013-9351
Subject:
cadmium; chronic exposure; creatinine; kidneys; men; risk; risk assessment; watersheds; women; Japan
Abstract:
... OBJECTIVES: The aim of this study was to evaluate the reference level of urinary cadmium (Cd) that caused renal effects. An updated hybrid approach was used to estimate the benchmark doses (BMDs) and their 95% lower confidence limits (BMDL) in subjects with a wide range of exposure to Cd. METHODS: The total number of subjects was 1509 (650 men and 859 women) in non-polluted areas and 3103 (1397 me ...
DOI:
10.1016/j.envres.2010.11.013

4. Association of laboratory data and death within one month in cats with chronic renal failure

Author:
Kuwahara, Y.; Ohba, Y.; Kitoh, K.; Kuwahara, N.; Kitagawa, H.
Source:
journal of small animal practice 2006 v.47 no.8 pp. 446-450
ISSN:
0022-4510
Subject:
urine; renal failure; blood chemistry; protein content; cats; prognosis; hematocrit; chronic diseases; creatinine; cat diseases; pets; phosphates; urea nitrogen; mortality; Japan
Abstract:
... To retrospectively compare the data taken at the first visit of 34 cats with chronic renal failure surviving more than one month (surviving group) and 16 cats dying within one month (non-surviving group). Records were collected on cats with chronic renal failure presented to a private veterinary practice in Nagoya, Japan, from March 1996 to March 2005. All cats with chronic renal failure diagnosed ...
DOI:
10.1111/j.1748-5827.2006.00200.x
PubMed:
16911112

5. Association of self-reported moderate vegetable juice intake with small decline in kidney function in a five-year prospective study

Author:
Ryosuke Fujii; Takaaki Kondo; Mineko Tsukamoto; Sayo Kawai; Tae Sasakabe; Mariko Naito; Yoko Kubo; Rieko Okada; Takashi Tamura; Asahi Hishida; Jun Ueyama; Yumi Hayashi; Joji Ohnishi; Nobuyuki Hamajima; Kenji Takeuchi; Kenji Wakai
Source:
Nutrition 2021 v.84 pp. 111114
ISSN:
0899-9007
Subject:
Japan; alcohols; beverages; blood serum; creatinine; decline; females; fruit consumption; fruits; glomerular filtration rate; prospective studies; vegetable juices; vegetables
Abstract:
... Although consumption of vegetable and 100% fruit juices are an acceptable alternative for vegetable and fruit intake, information about their actual effects on kidney function is sparse. The aim of this study was to determine the association between the consumption of vegetable and fruit juices and changes in kidney function in a Japanese population over a 5-y period.In this prospective study, we ...
DOI:
10.1016/j.nut.2020.111114

6. Bisphenol S in Urine from the United States and Seven Asian Countries: Occurrence and Human Exposures

Author:
Liao Chunyang; Liu Fang; Alomirah Husam; Loi Vu Duc; Mohd Mustafa Ali; Moon Hyo-Bang; Nakata Haruhiko; Kannan Kurunthachalam
Source:
Environmental Science & Technology 2012 v.46 no.12 pp. 6860-6866
ISSN:
1520-5851
Subject:
bisphenol A; creatinine; exposure assessment; females; geometry; high performance liquid chromatography; humans; males; pharmacokinetics; races; tandem mass spectrometry; toxicity; urine; China; India; Japan; Korean Peninsula; Kuwait; Malaysia; United States; Vietnam
Abstract:
... As concern regarding the toxic effects of bisphenol A (BPA) grows, BPA in many consumer products is gradually being replaced with compounds such as bisphenol S (BPS). Nevertheless, data on the occurrence of BPS in human specimens are limited. In this study, 315 urine samples, collected from the general populations in the United States, China, India, Japan, Korea, Kuwait, Malaysia, and Vietnam, wer ...
DOI:
10.1021/es301334j

7. Cadmium Exposure and Blood Telomere Length in Female University Students in Japan

Author:
Yuki Mizuno; Shoko Konishi; Hideki Imai; Eiji Fujimori; Nobuhiko Kojima; Jun Yoshinaga
Source:
Biological trace element research 2019 v.192 no.2 pp. 98-105
ISSN:
0163-4984
Subject:
DNA; atomic absorption spectrometry; blood; cadmium; college students; creatinine; females; lifestyle; quantitative polymerase chain reaction; questionnaires; telomeres; toxicity; Japan
Abstract:
... Cadmium is a toxic metal found ubiquitously throughout the world. Our study evaluated whether cadmium exposure was associated with telomere length in 73 female university students. Determination of telomere length was performed by quantitative polymerase chain reaction using DNA in blood. Urinary cadmium concentration was measured by inductively coupled plasma mass spectrometry. The students’ phys ...
DOI:
10.1007/s12011-019-1656-3

8. Canine lyme disease: clincial and serological evaluations in 21 dogs in Japan

Author:
Azuma, Y.; Isogai, E.; Isogai, H.; Kawamura, K.
Source:
Veterinary record 1994 v.134 no.15 pp. 369-372
ISSN:
0042-4900
Subject:
dogs; Borrelia burgdorferi; Lyme disease; body temperature; creatinine; Ixodes persulcatus; antibody formation; Japan
DOI:
10.1136/vr.134.15.369

9. Clinical Application of Plasma Clearance of Iohexol on Feline Patients

Author:
K Miyamoto
Source:
Journal of feline medicine and surgery v.3 no.3 pp. 143-147
ISSN:
1098-612X
Subject:
cats; glomerular filtration rate; blood plasma; urea; nitrogen; creatinine; kidney diseases; Japan
Abstract:
... Glomerular filtration rate (GFR) was estimated by plasma clearance of iohexol (PCio) in 52 conscious cats presented for a variety of reasons to Angel Animal Hospital over a 2-year period. Cats were divided into four groups according to their clinical conditions and reasons for measuring PCio. The median PCio (ml/min/kg) was 3.68 in normal cats (NM), 2.39 in cats with suspected renal disease (SP), ...
DOI:
10.1053/jfms.2001.0125
PubMed:
11876631

10. Cumulative exposure assessment of neonicotinoids and an investigation into their intake-related factors in young children in Japan

Author:
Naoko Oya; Yuki Ito; Takeshi Ebara; Sayaka Kato; Jun Ueyama; Arisa Aoi; Karin Nomasa; Hirotaka Sato; Taro Matsuki; Mayumi Sugiura-Ogasawara; Shinji Saitoh; Michihiro Kamijima
Source:
Science of the total environment 2021 v.750 pp. 141630
ISSN:
0048-9697
Subject:
Culicidae; Japan; children; creatinine; cumulative exposure; diet; dinotefuran; environment; exposure assessment; food choices; foods; insect repellents; lawns and turf; metabolites; odds ratio; surveys; tandem mass spectrometry; toxic substances; urine
Abstract:
... Exposure levels of neonicotinoids (NEO) in young children remain unknown, despite their widespread use and the plausible vulnerability of toddlers to environmental toxicants. Herein we aimed to clarify the exposure levels and sources of NEOs in young Japanese children. Disposable diapers were collected from 1036 children (16–23 months old) participating in an adjunct study of the Japan Environment ...
DOI:
10.1016/j.scitotenv.2020.141630

11. Exposure characterization of three major insecticide lines in urine of young children in Japan—neonicotinoids, organophosphates, and pyrethroids

Author:
Aya Osaka; Jun Ueyama; Takaaki Kondo; Hiroshi Nomura; Yuka Sugiura; Isao Saito; Kunihiko Nakane; Ayuko Takaishi; Hiroko Ogi; Shinya Wakusawa; Yuki Ito; Michihiro Kamijima
Source:
Environmental research 2016 v.147 pp. 89-96
ISSN:
0013-9351
Subject:
Japanese people; acetamiprid; carboxylic acids; children; clothianidin; creatinine; dinotefuran; exposure pathways; females; imidacloprid; males; metabolites; nitenpyram; organophosphorus compounds; pest control; pyrethrins; seasonal variation; summer; thiacloprid; thiamethoxam; toxic substances; urine; winter; Japan
Abstract:
... The use of neonicotinoid (NEO) insecticides has increased over the past decade not only in Japan but also worldwide, while organophosphate (OP) and pyrethroid (PYR) insecticides are still conventionally used in agriculture and domestic pest control. However, limited data are currently available on the NEO exposure levels, especially in children, who are particularly vulnerable to environmental tox ...
DOI:
10.1016/j.envres.2016.01.028

12. Exposure levels of organophosphate pesticides in Japanese diapered children: Contributions of exposure-related behaviors and mothers’ considerations of food selection and preparation

Author:
Naoko Oya; Yuki Ito; Takeshi Ebara; Sayaka Kato; Keisuke Hioki; Arisa Aoi; Jun Ueyama; Tomoko Oguri; Naoto Shoji; Mayumi Sugiura-Ogasawara; Shinji Saitoh; Michihiro Kamijima
Source:
Environment international 2020 v.134 pp. 105294
ISSN:
0160-4120
Subject:
Japanese people; children; creatinine; deodorants; food choices; foods; graphs; herbicides; insect repellents; insecticides; metabolites; mothers; multivariate analysis; odds ratio; odors; organophosphorus pesticides; public health; surveys; toddlers; urine; Japan
Abstract:
... Organophosphate (OP) pesticide exposure is a public health issue due to its potential link to neurodevelopmental problems in children. This study aimed to examine the exposure levels of OP pesticides in Japanese toddlers and explore the possible contributions of their exposure-related behaviors and their mothers’ considerations of food selection and preparation to their exposure levels to OP pesti ...
DOI:
10.1016/j.envint.2019.105294

13. Formulas developed based on the ratio of urea nitrogen to creatinine concentrations obtained from multiple spot urine samples are acceptable to predict protein intake at group level but not at individual level

Author:
Xiaoyi Yuan; Kentaro Murakami; Keiko Asakura; Ken Uechi; Shizuko Masayasu; Satoshi Sasaki
Source:
Nutrition research 2020 v.78 pp. 50-59
ISSN:
0271-5317
Subject:
creatinine; excretion; men; protein intake; standard deviation; t-test; urea nitrogen; urine; women; Japan
Abstract:
... In this study, we hypothesized that spot urine can be used to predict protein intake at both group and individual levels. Participants (n = 369) of this study were recruited from all 47 prefectures in Japan. Sex-specific formulas were developed based on the ratio of urea nitrogen to creatinine concentration obtained from 3 spot urine samples. Validity of the formulas was examined against two 24-ho ...
DOI:
10.1016/j.nutres.2020.04.004

14. Higher dietary cholesterol and ω-3 fatty acid intakes are associated with a lower success rate of Helicobacter pylori eradication therapy in Japan

Author:
Hiroaki Ikezaki; Norihiro Furusyo; Paul F Jacques; Motohiro Shimizu; Masayuki Murata; Ernst J Schaefer; Yoshihisa Urita; Jun Hayashi
Source:
American journal of clinical nutrition 2017 v.106 no.2 pp. 581-588
ISSN:
1938-3207
Subject:
C-reactive protein; Helicobacter pylori; amoxicillin; antibiotic resistance; antibodies; blood lipids; blood serum; breath tests; cholesterol; clarithromycin; creatinine; demography; duodenal ulcers; eggs; endoscopy; fish consumption; food frequency questionnaires; gastritis; glycohemoglobin; insulin; lansoprazole; nutrient intake; omega-3 fatty acids; regression analysis; risk factors; stomach neoplasms; vitamin D; Japan
Abstract:
... Background:Helicobacter pylori infection is a known risk factor for duodenal ulcers, gastritis, and gastric cancer. The eradication of H. pylori is successful in treating these disorders; however, the success rate of eradication therapy is declining. There may be an interaction with nutrient intake to account for this decline. Objective: We investigated the influence of food and nutrient intake on ...
DOI:
10.3945/ajcn.116.144873

15. Identification and sensory evaluation of flavour enhancers in Japanese traditional dried herring (Clupea pallasii) fillet

Author:
Shah, A.K.M.A.; Ogasawara, Masashi; Egi, Makoto; Kurihara, Hideyuki; Takahashi, Koretaro
Source:
Food chemistry 2010 v.122 no.1 pp. 249-253
ISSN:
0308-8146
Subject:
sensory properties; flavor enhancers; traditional foods; dried fish; herring; Clupea; fish fillets; food analysis; food composition; creatine; creatinine; Japan
Abstract:
... Flavour-enhancing components of dried herring fillet (migaki-nishin in Japanese) were isolated and evaluated for their effects on sensory perception. Sensory evaluation revealed that addition of dried herring fillet water-soluble extracts to Japanese noodle soup significantly (P <0.05) enhanced soup flavour characters, such as thickness, mouthfulness and continuity. The extracts were fractionated ...
DOI:
10.1016/j.foodchem.2010.02.072

16. Impact of Glycemic Control on Survival of Diabetic Patients on Chronic Regular Hemodialysis: A 7-year observational study

Author:
Oomichi, Takeshi; Emoto, Masanori; Tabata, Tsutomu; Morioka, Tomoaki; Tsujimoto, Yoshihiro; Tahara, Hideki; Shoji, Tetsuo; Nishizawa, Yoshiki
Source:
Diabetes care 2006 v.29 no.7 pp. 1496-1500
ISSN:
0149-5992
Subject:
blood pressure; blood serum; creatinine; glycemic control; hemodialysis; hemoglobin; kidney diseases; models; observational studies; patients; prognosis; surveys; Japan
Abstract:
... OBJECTIVE:--To investigate the impact of glycemic control during regular hemodialysis on the survival of diabetic patients with chronic kidney disease (CKD) in a longitudinal observational study. RESEARCH DESIGN AND METHODS--A total of 114 diabetic CKD patients on hemodialysis at Inoue Hospital (Suita, Japan) were surveyed from May 1995 to December 2002 (survey period 45.5 ± 29.3 [means ± SD] mont ...
DOI:
10.2337/dc05-1887

17. Low-Dose Aspirin Therapy in Patients With Type 2 Diabetes and Reduced Glomerular Filtration Rate: Subanalysis from the JPAD trial

Author:
Saito, Yoshihiko; Morimoto, Takeshi; Ogawa, Hisao; Nakayama, Masafumi; Uemura, Shiro; Doi, Naofumi; Jinnouchi, Hideaki; Waki, Masako; Soejima, Hirofumi; Sugiyama, Seigo; Okada, Sadanori; Akai, Yasuhiro
Source:
Diabetes care 2011 v.34 no.2 pp. 280-285
ISSN:
0149-5992
Subject:
aspirin; atherosclerosis; blood serum; creatinine; glomerular filtration rate; models; myocardial ischemia; noninsulin-dependent diabetes mellitus; patients; risk factors; stroke; therapeutics; Japan
Abstract:
... OBJECTIVE: Type 2 diabetes accompanied by renal damage is a strong risk factor for atherosclerotic events. The purpose of this study was to investigate the efficacy of low-dose aspirin therapy on primary prevention of atherosclerotic events in patients with type 2 diabetes and coexisting renal dysfunction. RESEARCH DESIGN AND METHODS: The Japanese Primary Prevention of Atherosclerosis With Aspirin ...
DOI:
10.2337/dc10-1615
PubMed:
21270185
PubMed Central:
PMC3024334

18. Measurement of urinary concentrations of the mycotoxins zearalenone and sterigmatocystin as biomarkers of exposure in mares

Author:
M Takagi; S Uno; E Kokushi; F Sato; MMP Wijayagunawardane; J Fink‐Gremmels
Source:
Reproduction in domestic animals 2018 v.53 no.1 pp. 68-73
ISSN:
0936-6768
Subject:
Thoroughbred; animal health; biomarkers; breeding; creatinine; farms; feed contamination; feeds; liquid chromatography; mares; metabolites; monitoring; pregnancy; stallions; sterigmatocystin; tandem mass spectrometry; urine; zearalenol; zearalenone; Japan
Abstract:
... Mycotoxins may affect animal health, including reproduction. Little is known about the clinical relevance of exposure of horses to contaminated feed. This study aimed at (i) monitoring the levels of the mycotoxins zearalenone (ZEN), with its metabolites α‐ and β‐zearalenol (α‐ and β‐ZOL), and sterigmatocystin (STC) in urine samples from thoroughbred mares in Japan and (ii) relating these findings ...
DOI:
10.1111/rda.13054

19. Natural severe fever with thrombocytopenia syndrome virus infection in domestic cats in Japan

Author:
Aya Matsuu; Yasuyuki Momoi; Akihiro Nishiguchi; Keita Noguchi; Mihoko Yabuki; Emu Hamakubo; Maho Take; Ken Maeda
Source:
Veterinary microbiology 2019 pp. -
ISSN:
0378-1135
Subject:
SFTS virus; amyloid; anorexia; bilirubin; blood serum; cat diseases; cats; creatinine; emerging diseases; enzymes; fever; leukopenia; mortality; pet ownership; phylogeny; public health; risk factors; thrombocytopenia; veterinary clinics; viruses; vomiting; zoonoses; Japan
Abstract:
... Severe fever with thrombocytopenia syndrome (SFTS) is a recently discovered emerging infectious disease. A zoonotic disease with a high fatality rate in human beings, clinical information on SFTS virus (SFTSV) infection in animals is important. Since 2017, we have diagnosed 24 client-owned cats living in western Japan with SFTS, by genetic and serological testing. In this study, we characterized t ...
DOI:
10.1016/j.vetmic.2019.06.019

20. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial

Author:
Maede Ruyvaran; Ali Zamani; Alireza Mohamadian; Mohammad M. Zarshenas; Mohammad Hassan Eftekhari; Saeedeh Pourahmad; Ebrahim Fallahzadeh Abarghooei; Abolfazl Akbari; Majid Nimrouzi
Source:
Journal of ethnopharmacology 2022 v.282 pp. 114590
ISSN:
0378-8741
Subject:
Carthamus tinctorius; Japan; adiponectin; antioxidants; blood glucose; blood serum; body mass index; clinical trials; creatinine; diastolic blood pressure; herbal medicines; insulin resistance; leptin; lifestyle; lipids; metabolic syndrome; obesity; placebos; risk; safflower oil; systolic blood pressure; traditional medicine; waist circumference; China; Korean Peninsula
Abstract:
... Carthamus tinctorius L. (Safflower) has been widely recommended to treat metabolic disorders in traditional herbal medicine in Persia, China, Korea, Japan, and other East-Asian countries. The anti-hypercholesterolemic and antioxidant effects of this plant have been well documented, but its protective effects against Metabolic Syndrome (MetS) have not been fully illustrated.The present study aimed ...
DOI:
10.1016/j.jep.2021.114590

21. Sensitivity and specificity of published strategies using urinary creatinine to identify incomplete 24-h urine collection

Author:
Murakami, K.; Sasaki, S.; Takahashi, Y.; Uenishi, K.; Watanabe, T.; Kohri, T.; Yamasaki, M.; Watanabe, R.; Baba, K.; Shibata, K.
Source:
Nutrition 2008 v.24 no.1 pp. 16-22
ISSN:
0899-9007
Subject:
women; urine; data collection; creatinine; accuracy; precision; epidemiology; volume; biomarkers; diet; Japan
Abstract:
... Objective: Although urinary creatinine has been used to identify incomplete 24-h urine in numerous epidemiologic studies, information on its utility is limited. We examined the sensitivity and specificity of several strategies that use creatinine to identify incomplete urine using the p-aminobenzoic acid (PABA) check method as reference. Methods: Subjects were 654 female Japanese dietetic students ...
DOI:
10.1016/j.nut.2007.09.001
PubMed:
17996421

22. Serum Parathyroid Hormone in Healthy Japanese Women in Relation to Serum 25-Hydroxyvitamin D

Author:
Kazutoshi Nakamura; Mitsue Nashimoto; Yasushi Hori; Masaharu Yamamoto
Source:
International journal for vitamin and nutrition research 2000 v.70 no.6 pp. 287-292
ISSN:
0300-9831
Subject:
women; blood chemistry; parathyroid hormone; vitamin D; creatinine; nationalities and ethnic groups; Japan
Abstract:
... The aim of this work was to clarify levels of serum parathyroid hormone (PTH) in healthy adult women and to study the relationship between PTH and 25-hydroxyvitamin D [25(OH)D]. One hundred sixty-nine healthy women aged 40 years or older in a community were studied. The average age of the subjects was 65.3 years (SD 8.2). All subjects had normal serum creatinine levels. Serum intact PTH and 25(OH) ...
DOI:
10.1024/0300-9831.70.6.287
PubMed:
11214353

23. Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan

Author:
Mirei Uetani; Etsuko Kobayashi; Yasushi Suwazono; Muneko Nishijo; Hideaki Nakagawa; Teruhiko Kido; Koji Nogawa
Source:
Biological trace element research 2006 v.110 no.2 pp. 107-117
ISSN:
0163-4984
Subject:
analysis of variance; blood; cadmium; creatinine; men; urine; Japan
Abstract:
... We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance was used to compare Cd concentrations in blood and urine of smokers with those of ...
DOI:
10.1385/BTER:110:2:107

24. Stable Ammonia-specific NAD Synthetase from Bacillus stearothermophilus: Purification, Characterization, Gene Cloning, and Applications

Author:
Fumihiko YAMAGUCHI; Shinji KOGA; Issei YOSHIOKA; Mamoru TAKAHASHI; Haruhiko SAKURABA; Toshihisa OHSHIMA
Source:
Bioscience, biotechnology, and biochemistry 2002 v.66 no.10 pp. 2052-2059
ISSN:
1347-6947
Subject:
Bacillus subtilis; Escherichia coli; Geobacillus stearothermophilus; Japan; amino acid sequences; ammonia; asparagine; biotechnology; creatinine; enzyme activity; gel chromatography; genes; glutamine; hot springs; ligases; molecular weight; pH; polyacrylamide gel electrophoresis; temperature; urea; uric acid
Abstract:
... Bacillus stearothermophilus H-804 isolated from a hot spring in Beppu, Japan, produced an ammonia-specific NAD synthetase (EC 6.3.1.5). The enzyme specifically used NH₃ as an amide donor for the synthesis of NAD as it formed AMP and pyrophosphate from deamide-NAD and ATP. None of the l-amino acids tested, such as l-asparagine or l-glutamine, or other amino compounds such as urea, uric acid, or cre ...
DOI:
10.1271/bbb.66.2052

25. The consumption of seaweed as a protective factor in the etiology of breast cancer: proof of principle

Author:
Jane Teas; Sylvia Vena; D. Lindsie Cone; Mohammad Irhimeh
Source:
Journal of applied phycology 2013 v.25 no.3 pp. 771-779
ISSN:
0921-8971
Subject:
Undaria; analysis of variance; blood; blood proteins; breast neoplasms; complement; creatinine; enzyme-linked immunosorbent assay; humans; macroalgae; mass spectrometry; mortality; patients; plasminogen activator; postmenopause; prognosis; protein synthesis; urine; women; Japan
Abstract:
... Daily consumption of seaweed has been proposed as a factor in explaining lower postmenopausal breast cancer (BC) incidence and mortality rates in Japan. This clinical trial assessed the impact of introducing seaweed- to non-seaweed-consuming American postmenopausal women. Fifteen healthy postmenopausal women were recruited for a 3-month single-blinded placebo controlled clinical trial; five had no ...
DOI:
10.1007/s10811-012-9931-0
PubMed:
23678231
PubMed Central:
PMC3651528

26. Trigonella stellata reduced the deleterious effects of diabetes mellitus through alleviation of oxidative stress, antioxidant- and drug-metabolizing enzymes activities

Author:
Salah A. Sheweita; Sara A. ElHady; Hala M. Hammoda
Source:
Journal of ethnopharmacology 2020 v.256 pp. 112821
ISSN:
0378-8741
Subject:
NADH dehydrogenase; Trigonella; adverse effects; animal disease models; anti-inflammatory activity; antioxidant enzymes; appetite; bilirubin; biomarkers; blood glucose; catalase; creatinine; diabetes mellitus; drugs; enzyme activity; gamma-glutamyltransferase; glutathione; glutathione peroxidase; glutathione transferase; glutathione-disulfide reductase; histopathology; hypocholesterolemia; hypoglycemia; immunoblotting; isozymes; kidneys; lactate dehydrogenase; liver; matrix-assisted laser desorption-ionization mass spectrometry; oxidative stress; patients; protective effect; protein synthesis; rats; superoxide dismutase; therapeutics; tissues; traditional medicine; transaminases; urea; xenobiotics; China; Egypt; India; Japan
Abstract:
... Genus Trigonella has a history of folkloric medicinal uses in China, Japan, Egypt and India. There are a variety of therapeutic actions of Trigonella including hypocholesterolemia, hypoglycemia, antibacterial, antiviral, anti-inflammatory activities, antioxidants and appetite stimulant.The prevalence of diabetes mellitus is increasing annually. The present study aims at investigating the protectiv ...
DOI:
10.1016/j.jep.2020.112821

27. Urinary monohydroxylated metabolites of polycyclic aromatic hydrocarbons in children living in city and rural residences in Southern China

Author:
Yu Wang; Ruifang Fan; Yulian Dong; Wenbing Zhang; Guoying Sheng; Jiamo Fu
Source:
Environmental technology 2014 v.35 no.23 pp. 2973-2981
ISSN:
1479-487X
Subject:
air; children; creatinine; environmental technology; excretion; metabolites; parents; polycyclic aromatic hydrocarbons; soil; students; China; Denmark; Germany; Japan; Korean Peninsula; Spain; Taiwan; Thailand; Ukraine; United States
Abstract:
... Urinary 2-hydroxynaphthalene, 2-hydoxyfluorene, 9-hydroxyphenanthrene, 1-hydroxypyrene and 3-hydroxybenz[a]pyrene concentrations in 179 randomly selected voluntary students were determined in the Southern China, aged 14–16 and living in four areas with different levels of polycyclic aromatic hydrocarbons (PAHs) in soil, water and ambient air. The excretion of 1-hydroxypyrene is significantly highe ...
DOI:
10.1080/09593330.2014.927532