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Leucojum aestivum
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- Author:
- Strahil Berkov; Lilyia Georgieva; Boriana Sidjimova; Jaume Bastida
- Source:
- Industrial crops and products 2022 v.178 pp. 114619
- ISSN:
- 0926-6690
- Subject:
- Leucojum aestivum, etc ; Hippeastrum; Lycoris radiata; Narcissus pseudonarcissus; acclimation; alkaloids; biomass; bulbs; charcoal; dormancy; genotype; greenhouses; ornamental plants; Show all 13 Subjects
- Abstract:
- ... Galanthamine is a natural compound used for the treatment of Alhzeimer’s disease. Currently, it is extracted at industrial scale from Narcissus pseudonarcissus cv. Carlton, Lycoris radiata and Leucojum aestivum. Hippeastrum papilio is an ornamental plant which shows advantages in comparison to the currently used plants for galanthamine extraction. It is a plant without a period of dormancy with bu ...
- DOI:
- 10.1016/j.indcrop.2022.114619
- https://doi.org/10.1016/j.indcrop.2022.114619
- Author:
- Muhammed Tural Ates; Arzu Birinci Yildirim; Arzu Ucar Turker
- Source:
- South African journal of botany 2021 v.140 pp. 182-188
- ISSN:
- 0254-6299
- Subject:
- Leucojum aestivum, etc ; Alzheimer disease; antimalarials; antioxidant activity; bioactive compounds; bulbs; catalase; free radicals; growth and development; lycorine; methanol; salt stress; salt tolerance; summer; superoxide dismutase; water content; Show all 16 Subjects
- Abstract:
- ... Summer snowflake (Leucojum aestivum L.) is a bulbous plant to the Amaryllidaceae family. L. aestivum is a Euro-Mediterranean region plant and is a well-known source of pharmacologically important alkaloids. Galanthamine is the major bioactive compound that is widely used in the treatment of neurological disorders, including Alzheimer's disease. Another alkaloid lycorine has antitumor, antimalarial ...
- DOI:
- 10.1016/j.sajb.2021.04.016
- https://doi.org/10.1016/j.sajb.2021.04.016
- Author:
- Liliya Georgievaa; Strahil Berkov; Violeta Kondakova; Jaume Bastida; Francesc Viladomat; Atanas Atanassov; Carles Codina
- Source:
- Zeitschrift für Naturforschung 2014 v.62 no.9-10 pp. 627-635
- ISSN:
- 1865-7125
- Subject:
- Leucojum aestivum, etc ; Alzheimer disease; acetylcholinesterase; bulbs; gas chromatography-mass spectrometry; lycorine; summer; Bulgaria; Show all 8 Subjects
- Abstract:
- ... Leucojum aestivum (summer snowflake) is a plant species used for the extraction of galanthamine, an acetylcholinesterase inhibitor for the treatment of Alzheimer’s disease. Extracts from bulbs collected from 18 Bulgarian populations and from shoot-clumps obtained in vitro from 8 different populations showed variations in their alkaloid composition. Nineteen alkaloids were detected in the studied s ...
- DOI:
- 10.1515/znc-2007-9-1002
- https://doi.org/10.1515/znc-2007-9-1002
- Author:
- Agata Ptak
- Source:
- Open life sciences 2014 v.9 no.11 pp. 1011-1021
- ISSN:
- 2391-5412
- Subject:
- Leucojum aestivum, etc ; microscopy; paclobutrazol; survival rate; sucrose; gibberellic acid; acclimation; nuclear genome; bulbs; stomata; roots; Show all 11 Subjects
- Abstract:
- ... The effects of growth retardants (paclobutrazol and ancymidol), sucrose, GA3 (gibberellic acid) and physical state of the medium (solid and liquid — Rita® temporary immersion system) on in vitro induction of Leucojum aestivum bulbs and their acclimatization were studied. Paclobutrazol, regardless of the physical state of the medium, stimulated the formation of bulbs (99.3%). Under the influence 90 ...
- DOI:
- 10.2478/s11535-014-0339-5
- https://doi.org/10.2478/s11535-014-0339-5
5. Influence of auxins on somatic embryogenesis and alkaloid accumulation in Leucojum aestivum callus
- Author:
- Agata Ptak; Anna Tahchy; Edyta Skrzypek; Tomasz Wójtowicz; Dominique Laurain-Mattar
- Source:
- Open life sciences 2013 v.8 no.6 pp. 591-599
- ISSN:
- 2391-5412
- Subject:
- Leucojum aestivum, etc ; 2,4-D; Alzheimer disease; alkaloids; auxins; bulbs; callus; callus culture; dicamba; explants; growing media; phenolic compounds; picloram; polyethylene glycol; somatic embryogenesis; Show all 15 Subjects
- Abstract:
- ... In vitro cultures of Leucojum aestivum are considered as an alternative for the production of galanthamine, which is used for the symptomatic treatment of Alzheimer’s disease. We studied the effects of auxins 2,4-dichlorophenoxyacetic acid (2,4-D), 4-amino-3,5,6-trichloropicolinic acid (picloram), 3,6-dichloro-o-anisic acid (dicamba) at concentrations of 25 and 50 µM on the induction of embryogeni ...
- DOI:
- 10.2478/s11535-013-0160-y
- https://doi.org/10.2478/s11535-013-0160-y
- Author:
- Gilberto Parolo; Thomas Abeli; Graziano Rossi; Giuseppina Dowgiallo; Diethart Matthies
- Source:
- Perspectives in plant ecology, evolution and systematics 2011 v.13 no.4 pp. 319-330
- ISSN:
- 1433-8319
- Subject:
- Leucojum aestivum, etc ; alkaloids; alluvial soils; bulbs; eggs; flora; geophytes; habitats; harvesting; nitrogen; nitrogen content; pollen; population; population size; protected species; reproduction; seed germination; seed set; soil water content; temperature; wetlands; Central European region; Europe; Show all 23 Subjects
- Abstract:
- ... Leucojum aestivum L. (Amaryllidaceae) is a polycarpic C-S-European/W-Asiatic geophyte. It is a threatened wetland species and is protected in several European countries, as a consequence of the destruction or alteration of its habitats across Europe and the harvesting of its bulbs for medical purposes (alkaloids). This paper deals with the taxonomic status, morphology, distribution, ecology and po ...
- DOI:
- 10.1016/j.ppees.2011.05.004
- https://doi.org/10.1016/j.ppees.2011.05.004
- Author:
- Strahil Berkov; Jaume Bastida; Francesc Viladomat; Carles Codina
- Source:
- Talanta 2011 v.83 no.5 pp. 1455-1465
- ISSN:
- 0039-9140
- Subject:
- Leucojum aestivum, etc ; Alzheimer disease; Narcissus; acetylcholinesterase; bulbs; gas chromatography-mass spectrometry; high performance liquid chromatography; leaves; metabolomics; methanol; nuclear magnetic resonance spectroscopy; pharmaceutical industry; principal component analysis; quality control; rapid methods; raw materials; Show all 16 Subjects
- Abstract:
- ... Galanthamine, an acetylcholinesterase inhibitor marketed as a hydrobromide salt for the treatment of Alzheimer's disease, is obtained from some Amaryllidaceae plants. A new method was developed and validated for its quantification by GC–MS in different plant sources: bulbs and leaves from Narcissus confusus; bulbs from N. pseudonarcissus cv. Carlton; and leaves and in vitro cultures from L. aestiv ...
- DOI:
- 10.1016/j.talanta.2010.11.029
- https://doi.org/10.1016/j.talanta.2010.11.029
- Author:
- Sandler-Ziv, D.; Fintea, C.; Noy Porat, T.; Kamenetsky, R.; Mathew, D.
- Source:
- Acta horticulturae 2011 v. no.886 pp. 225-231
- ISSN:
- 0567-7572
- Subject:
- Leucojum aestivum, etc ; bulbs; container-grown plants; cut flowers; dormancy; environmental factors; flowering; flowers; landscaping; leaves; plant growth; rock gardens; scanning electron microscopy; spring; sprouting; summer; temperature; winter; Israel; Mediterranean region; Show all 20 Subjects
- Abstract:
- ... Leucojum aestivum is a relatively small bulbous crop, usually grown for landscaping and rock gardens, but several varieties and selections are also used as cut flowers or potted plants. This species originates from the Mediterranean area, where summers are hot and dry, but winter conditions are favourable for plant growth and development. In Israel, sprouting begins in the fall, leaves and floral ...
- Author:
- Bogdanova, Yuliyana; Stoeva, Tatyana; Yanev, Stanislav; Pandova, Bozhidarka; Molle, Emil; Burrus, Monique; Stanilova, Marina
- Source:
- In vitro cellular & developmental biology 2009 v.45 no.4 pp. 458-465
- ISSN:
- 1054-5476
- Subject:
- Leucojum aestivum, etc ; biosynthesis; bulbs; clones; industry; lycorine; raw materials; shoots; summer; Bulgaria; Show all 10 Subjects
- Abstract:
- ... The investigation deals with in vitro clonal propagation of L. aestivum L. (summer snowflake), a threatened Amaryllidaceae plant species in Bulgaria used in the pharmaceutical industry as raw material for production of galanthamine-based medicines. Plants of known origin and with different alkaloid profile were taken from the living collection of the Institute of Botany, Sofia. Bulbs were used to ...
- DOI:
- 10.1007/s11627-008-9178-2
- PubMed:
- 32214772
- PubMed Central:
- PMC7089496
- https://doi.org/10.1007/s11627-008-9178-2
- Author:
- Stanilova, M.I.; Ilcheva, V.P.; Zagorska, N.A.
- Source:
- Plant cell reports 1994 v.13 no.8 pp. 451-453
- ISSN:
- 0721-7714
- Subject:
- Leucojum aestivum, etc ; kinetin; gynoecium; morphogenesis; explants; Lilium; bulbs; benzyladenine; micropropagation; naphthaleneacetic acid; temperature; gamma radiation; culture media; leaves; Show all 14 Subjects
- Abstract:
- ... The present work deals with the in vitro methods for rapid propagation, and morphogenetic potential of the rare and endangered bulb species Leucojum aestivum L., Amaryllidaceae, and Lilium rhodopaeum Delip., Liliaceae. The morphogenetic potential of different plant organs (bulb, stem, leaves and ovaries) was studied. Leaves of Leucojum aestivum L. and basal parts of the bulb in Lilium rhodopaeum D ...
- DOI:
- 10.1007/BF00231965
- PubMed:
- 24194024
- https://doi.org/10.1007/BF00231965