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Oriental traditional medicine
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- Author:
- Yu He; Qisen Li; Meiling Su; Wendong Huang; Banghao Zhu
- Source:
- Biochemical and biophysical research communications 2016 v.476 pp. 560-565
- ISSN:
- 0006-291X
- Subject:
- Oriental traditional medicine; animal ovaries; anterior pituitary; antifertility effect; blood serum; drugs; exocytosis; follicle-stimulating hormone; intragastric administration; luteinizing hormone; pregnancy rate; proteins; rats; secretion; toxicity testing
- Abstract:
- ... Zicao is being highlighted as a promising Chinese medicine due to all the beneficial effects that have been associated with its use. Unfortunately, studies on the toxicity of Zicao in different species are still missing and should be carried out. In this study, we investigated whether Acetylshikonin (AS) from Zicao has an anti-fertility effect through mating experiments and explored its underling ...
- DOI:
- 10.1016/j.bbrc.2016.05.162
- https://doi.org/10.1016/j.bbrc.2016.05.162
- Author:
- Di Qin; Huijie Zhang; Hongfei Zhang; Tongyi Sun; Hongbin Zhao; Wen-Hui Lee
- Source:
- Journal of ethnopharmacology 2019 v.244 pp. 112045
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Western blotting; acetylcysteine; acid phosphatase; alkaline phosphatase; animal models; animal ovaries; beta catenin; blood serum; bone formation; cartilage; collagen; eosin; femur; gene expression regulation; histology; interleukin-6; ligands; malondialdehyde; medicinal plants; messenger RNA; mice; micro-computed tomography; microstructure; nationalities and ethnic groups; osteocalcin; osteoporosis; ovariectomy; oxidative stress; pathogenesis; protective effect; quantitative polymerase chain reaction; rats; reactive oxygen species; staining; superoxide dismutase; transcription factor NF-kappa B; transforming growth factor beta 1; China
- Abstract:
- ... Osteoking is a Traditional Chinese Medicine consisting of seven types of medicinal herbs originated from Yi nationality and has been used in clinic to treat bone diseases for thousands of years in China. Osteoking shows excellent clinical therapeutic effects on osteoporosis, but it is not clear whether Osteoking could exhibit beneficial effects against osteoporosis via reducing reactive oxygen spe ...
- DOI:
- 10.1016/j.jep.2019.112045
- https://doi.org/10.1016/j.jep.2019.112045
- Author:
- Guoqiang Jiang; Jia Liu; Baoyin Ren; Yawei Tang; Lawrence Owusu; Man Li; Jing Zhang; Likun Liu; Weiling Li
- Source:
- Journal of ethnopharmacology 2016 v.193 pp. 368-376
- ISSN:
- 0378-8741
- Subject:
- Cnidium monnieri; Oriental traditional medicine; animal ovaries; anti-inflammatory activity; antineoplastic agents; apoptosis; caspases; cell cycle checkpoints; cell viability; dose response; flow cytometry; metalloproteinases; migratory behavior; models; neoplasm cells; ovarian neoplasms; tissue repair
- Abstract:
- ... Cnidium monnieri (L.) Cusson is a commonly used traditional Chinese medicine to treat gynecological disease in some countries. Osthole, an active O-methylated coumadin isolated from Cnidium monnieri (L.) Cusson, has been shown to induce various beneficial biochemical effects such as anti-seizure and anti-inflammatory effects. However, the anti-tumor mechanism of osthole is not well known.Here, we ...
- DOI:
- 10.1016/j.jep.2016.08.045
- https://doi.org/10.1016/j.jep.2016.08.045
- Author:
- Mei Lin; Bairong Xia; Meng Yang; Shu Gao; Yanqiu Huo; Ge Lou
- Source:
- International journal of biological macromolecules 2013 v.53 no. pp. 72-76
- ISSN:
- 0141-8130
- Subject:
- DNA; Menispermum dauricum; Oriental traditional medicine; absorption; animal ovaries; antineoplastic agents; apoptosis; carcinoma; cell proliferation; gas chromatography; glutathione; humans; molecular weight; polysaccharides; reactive oxygen species; rhizomes; sodium hydroxide; transcription factor NF-kappa B
- Abstract:
- ... The rhizome of Menispermum dauricum DC (Menispermaceae) is one of the most commonly used traditional Chinese medicines officially listed in Chinese Pharmacopeia. In present study, we purified a water-soluble polysaccharide (WMDP) from this plant and investigated its physicochemical properties. WMDP was a homogeneous polysaccharide, with an average molecular weight of approximately 3.5×10⁴Da, as de ...
- DOI:
- 10.1016/j.ijbiomac.2012.11.012
- https://doi.org/10.1016/j.ijbiomac.2012.11.012
- Author:
- Ying Xue; Jibin Dong; Jianying Liang
- Source:
- Journal of separation science 2016 v.39 no.6 pp. 1067-1072
- ISSN:
- 1615-9306
- Subject:
- Chinese hamsters; Oriental traditional medicine; animal ovaries; atherosclerosis; emodin; high performance liquid chromatography; prediction; resveratrol; sphingomyelins; tandem mass spectrometry
- Abstract:
- ... A novel strategy for predicting bioactive components in traditional Chinese medicines using Chinese hamster ovary‐sphingomyelin synthase2 (CHO‐SMS₂) cell biospecific extraction and high‐performance liquid chromatography with diode array detection and tandem mass spectrometry analysis was proposed. The hypothesis is that when cells are incubated with the extract of traditional Chinese medicines, th ...
- DOI:
- 10.1002/jssc.201501075
- https://doi.org/10.1002/jssc.201501075
- Author:
- J. Lu; R. N. S. Wong; L. Zhang; R. Y. L. Wong; T. B. Ng; K. F. Lee; Y. B. Zhang; L. X. Lao; J. Y. Liu; S. C. W. Sze
- Source:
- Applied biochemistry and biotechnology 2016 v.180 no.1 pp. 79-93
- ISSN:
- 0273-2289
- Subject:
- Dioscorea; Oriental traditional medicine; animal ovaries; antibodies; aromatase; bioactive properties; biosynthesis; chromatography; estradiol; estrogen receptors; females; menopause; ovarian neoplasms; phenotype; protein synthesis; regulatory proteins; rhizomes; risk; screening; translation (genetics)
- Abstract:
- ... Rhizomes of Dioscorea species are traditionally used for relieving menopausal syndromes in Chinese medicine. The estrogen-stimulating bioactive principles have been demonstrated in our previous study. In this study, the estrogen-stimulating effects of proteins isolated from four Dioscorea species [D. alata L. (DA), D. zingiberensis C.H. Wright (DH), D. collettii var. hypoglauca (Palib.) S.J. Pei & ...
- DOI:
- 10.1007/s12010-016-2084-x
- https://doi.org/10.1007/s12010-016-2084-x
- Author:
- Xiao Wu; Rong Guan; Yuexin Liu; Shanhu Wu; Min Song; Taijun Hang
- Source:
- Journal of ethnopharmacology 2020 v.249 pp. 112370
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; animal ovaries; arsenic; atomic absorption spectrometry; drugs; fluorescence emission spectroscopy; health effects assessments; heart; high performance liquid chromatography; histopathology; kidneys; liver; lungs; oral administration; rats; risk; spleen; sulfides; tissue distribution; toxicity; uterus; China
- Abstract:
- ... Realgar (As₂S₂), a mineral traditional Chinese medicine (TCM), is proved to have great therapeutic effects in clinic and has been widely used in China for hundreds of years. As one of the most popular realgar-containing TCMs, NiuHuangJieDu Tablets (NHJDT) is used as OTC (over-the-counter) drug in daily life for fever relieving, detoxicating, as well as cure of sore throat and gingival swelling. Ho ...
- DOI:
- 10.1016/j.jep.2019.112370
- https://doi.org/10.1016/j.jep.2019.112370
- Author:
- Xueqin Ma; Jingjing Liu; Lingling Yang; Bo Zhang; Yanhong Dong; Qipeng Zhao
- Source:
- Life sciences 2018 v.209 pp. 140-148
- ISSN:
- 0024-3205
- Subject:
- Cynomorium songaricum; Oriental traditional medicine; animal ovaries; body weight; bone density; bone resorption; calcium; estradiol; ethanol; kidneys; laparotomy; ligands; mineral content; models; non-specific serine/threonine protein kinase; ovariectomy; phosphatidylinositol 3-kinase; phosphorus; rats; transcription factor NF-kappa B
- Abstract:
- ... Cynomorium songaricum Rupr., an edible and important Traditional Chinese medicine has long been used in folk for treatment of kidney deficiency, was chosen to estimate the antiosteoporotic activity and underlying molecular mechanism on rats induced by ovariectomy (OVX).9 of 45 rats were underwent bilateral laparotomy without removing the ovaries as sham group, remains were underwent bilateral ovar ...
- DOI:
- 10.1016/j.lfs.2018.08.008
- https://doi.org/10.1016/j.lfs.2018.08.008
- Author:
- Dong Yao; Zheng Wang; Li Miao; Linyan Wang
- Source:
- Journal of ethnopharmacology 2016 v.191 pp. 264-272
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Carthamus tinctorius; Oriental traditional medicine; adenosine; analgesia; animal ovaries; anti-inflammatory activity; antioxidant activity; blood; cell proliferation; coronary vessels; cytidine; fibrosis; free radical scavengers; immune system; immunomodulators; iron; menstruation; myocardial ischemia; pain; platelet aggregation; prothrombin; rats; thrombin; thromboplastin
- Abstract:
- ... Carthamus tinctorius is used as one of the Traditional Chinese Medicine (TCM) materials in prescriptions and composite to promote blood circulation to remove blood stasis, regulate menstruation and alleviate pain for over 2500 years. Modern pharmacological experiments have demonstrated that safflower has wide-reaching biological activities, including dilating coronary artery, modulating immune sys ...
- DOI:
- 10.1016/j.jep.2016.06.009
- https://doi.org/10.1016/j.jep.2016.06.009
- Author:
- Shengli Gao; Hideo Satsu; Toshiaki Makino
- Source:
- Natural medicines 2018 v.72 no.2 pp. 530-536
- ISSN:
- 1340-3443
- Subject:
- Zingiber officinale; inhibitory concentration 50; mechanism of action; Saposhnikovia divaricata; metabolic syndrome; drugs; cytotoxicity; high fructose corn syrup; plant ovary; beverages; glucose transporters; intestinal absorption; intestines; animal ovaries; obesity; rhizomes; fructose; Chinese hamsters; Platycodon grandiflorus; Oriental traditional medicine
- Abstract:
- ... Bofutsushosan (BTS; fang feng tong sheng san in Chinese) is a formula in traditional Japanese Kampo medicine and Chinese medicine comprising eighteen crude drugs, and is used to treat obesity and metabolic syndrome. Fructose is contained in refreshing beverages as high-fructose corn syrup, and is associated with obesity. Fructose is absorbed via glucose transporter 5 (GLUT5) in the intestine. Ther ...
- DOI:
- 10.1007/s11418-018-1183-0
- https://doi.org/10.1007/s11418-018-1183-0
- Author:
- Xiao-Meng WAN; Mu ZHANG; Pei ZHANG; Zhi-Shen XIE; Feng-Guo XU; Ping ZHOU; Shi-Ping MA; Xiao-Jun XU
- Source:
- Chinese journal of natural medicines 2016 v.14 no.11 pp. 823-834
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; adults; amino acids; animal ovaries; animal tissues; antagonists; blood serum; carcinogenesis; cardiovascular diseases; drug therapy; epithelial cells; estrogen receptors; females; glucose; human cell lines; hyperlipidemia; insulin resistance; insulin secretion; islets of Langerhans; mammary glands; menopause; metabolic syndrome; metabolomics; ovariectomy; rats; risk factors
- Abstract:
- ... Menopausal metabolic syndrome (MMS) is a series of syndrome caused by ovarian function decline and hormone insufficiency, and is a high risk factor for cardiovascular diseases (CVD) and type II diabetes mellitus (T2DM). Erzhiwan (EZW), composed of Herba Ecliptae and Fructus Ligustri Lucidi, is a traditional Chinese herbal formula that has been used to treat menopausal syndrome for many years. We a ...
- DOI:
- 10.1016/S1875-5364(16)30099-1
- https://doi.org/10.1016/S1875-5364(16)30099-1
- Author:
- Zhixia Qiu; Jingjing Dong; Chu Xue; Xiaonan Li; Kang Liu; Baolin Liu; Jun Cheng; Fang Huang
- Source:
- Journal of ethnopharmacology 2020 v.250 pp. 111965
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; Western blotting; abnormal development; animal ovaries; blood serum; diabetes; disease progression; estradiol; fasting; female fertility; females; follicle-stimulating hormone; follicle-stimulating hormone receptors; gene expression regulation; high fat diet; insulin; insulin resistance; luteinizing hormone; menopause; messenger RNA; metformin; models; pathogenesis; phosphatidylinositol 3-kinase; phosphorylation; polycystic ovary syndrome; progesterone; radioimmunoassays; rats; signal transduction; staining; testosterone; therapeutics; women
- Abstract:
- ... Polycystic ovary syndrome (PCOS) is a complex gynecological endocrine disease commonly occurred in women of childbearing age. The main hallmark of PCOS includes elevated androgen production and insulin resistance (IR). Liuwei Dihuang Pills (LWDH Pills), a commonly prescribed traditional Chinese medicine (TCM) is widely used as a tonic prescription to treat diabetes, female menopause syndrome and o ...
- DOI:
- 10.1016/j.jep.2019.111965
- https://doi.org/10.1016/j.jep.2019.111965
- Author:
- Xiaoting Yang; Wanqiu Wang; Yan Zhang; Jintao Wang; Fengjie Huang
- Source:
- Life sciences 2019 v.229 pp. 166-172
- ISSN:
- 0024-3205
- Subject:
- Oriental traditional medicine; Western blotting; animal ovaries; antioxidant activity; apoptosis; blood serum; enzyme-linked immunosorbent assay; females; fibrosis; follicle-stimulating hormone; follicular atresia; genes; messenger RNA; oocytes; oxidative stress; protein synthesis; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; secretion; therapeutics
- Abstract:
- ... Ovarian aging is a natural physiological phenomenon accompanied by follicular atresia as well as the decline of oocyte quality. Moxibustion is a form of traditional Chinese medicine therapy which has been reported to treat many aging-related problems and improve immune defense.Moxibustion treatment was applied to the 10-month female rats for 2 or 6 months to evaluate whether moxibustion could dela ...
- DOI:
- 10.1016/j.lfs.2019.05.040
- https://doi.org/10.1016/j.lfs.2019.05.040
- Author:
- Zhihui Liu; Xiao Zheng; Jiajia Lv; Xiaowen Zhou; Qiong Wang; Xiaozhou Wen; Huan Liu; Jingyi Jiang; Liling Wang
- Source:
- Phytomedicine 2015 v.22 pp. 573-578
- ISSN:
- 0944-7113
- Subject:
- breast neoplasms; rats; Taxus wallichiana var. chinensis; bioavailability; cytotoxicity; tissue distribution; taxanes; tandem mass spectrometry; antineoplastic agents; tissues; neoplasm cells; paclitaxel; oral administration; blood; animal ovaries; pharmacokinetics; Oriental traditional medicine; ovarian neoplasms; China
- Abstract:
- ... Taxus chinensis (Pilger) Rehd is widely distributed in China and the northern hemisphere, and the most popular medicinal component isolated from Taxus chinensis is paclitaxel (PTX), which has now become the first-line chemotherapeutic drug for breast cancer and ovarian cancer. Oral administration of pure PTX as a potential anti-cancer agent is compromised by low bioavailability.In the clinical pra ...
- DOI:
- 10.1016/j.phymed.2015.03.011
- https://doi.org/10.1016/j.phymed.2015.03.011
- Author:
- Ruxin Zhang; Shuang Hu; Xuan Chen; Xiaohong Bai
- Source:
- Chromatographia 2016 v.79 no.3-4 pp. 125-136
- ISSN:
- 0009-5893
- Subject:
- Oriental traditional medicine; alkaloids; animal ovaries; binding sites; breast neoplasms; cell membranes; hepatoma; high performance liquid chromatography; humans; liquid-phase microextraction; organelles; ovarian neoplasms; receptors; screening; survival rate
- Abstract:
- ... Hollow fiber cell fishing with high-performance liquid chromatography (HFCF-HPLC) based on human breast cancer MCF-7 cells, human renal tubular ACHN cells, human ovarian cancer SKOV-3 cells, and hepatoma HepG-2 cells, and their cell membranes, cell organelles, or receptors was developed and employed to research the active matrine alkaloids group, such as oxymatrine, matrine, sophoridine, and oxyso ...
- DOI:
- 10.1007/s10337-015-3006-8
- https://doi.org/10.1007/s10337-015-3006-8
- Author:
- Shi Wei Wang; Ho Pan Cheung; Yao Tong; Jia Lu; Tzi Bun Ng; Yan Bo Zhang; Zhang-Jin Zhang; Kai Fai Lee; Jenny Ka Wing Lam; Stephen Cho Wing Sze
- Source:
- Journal of ethnopharmacology 2017 v.195 pp. 188-195
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; animal models; animal ovaries; aromatase; blood serum; breast neoplasms; estradiol; estrogen receptors; females; immunoblotting; in vitro studies; menopause; neoplasm cells; non-specific serine/threonine protein kinase; rats; China
- Abstract:
- ... Erxian decoction (EXD), an empirical Chinese medicine formula, is effectively used in the clinical treatment of menopause-related symptoms in China. Previous data from our group show that EXD has steroidogenic effect on natural menopausal Sprague–Dawley-rats (SD-rats) as an animal model of menopause. However, the mechanistic studies on steroidogenic effects of EXD are still inadequate. Hence, the ...
- DOI:
- 10.1016/j.jep.2016.11.018
- https://doi.org/10.1016/j.jep.2016.11.018
- Author:
- Shuwan Wang; Jingjing Gao; Qingyu Li; Wanjun Ming; Yanjin Fu; Linliang Song; Jiajia Qin
- Source:
- Journal of ethnopharmacology 2020 v.262 pp. 113189
- ISSN:
- 0378-8741
- Subject:
- Epimedium brevicornu; Oriental traditional medicine; Western blotting; animal ovaries; antineoplastic agents; apoptosis; cell proliferation; computer software; enzyme inhibition; gene ontology; genes; glycosides; icariin; interleukin-2; kidneys; ovarian neoplasms; pharmacology; phosphatidylinositol 3-kinase; protein-protein interactions; quantitative polymerase chain reaction; signal transduction; tumor necrosis factors
- Abstract:
- ... Herba Epimedii (Berberidaceae) has the advantages of “nourishing the kidney and reinforcing the Yang”. Many species in this genus have long been used in traditional Chinese medicine (TCM) and have been used as anticancer drugs in traditional Chinese herbal medicine formulations. Icariin, a major flavonoid glycoside extracted from Epimedium brevicornum Maxim, has been widely proven to exert an inhi ...
- DOI:
- 10.1016/j.jep.2020.113189
- https://doi.org/10.1016/j.jep.2020.113189
- Author:
- Peng-Cheng LIN; Lin-Lin JI; Xiang-Jian ZHONG; Jin-Jie LI; Xin WANG; Xiao-Ya SHANG; Sheng LIN
- Source:
- Chinese journal of natural medicines 2019 v.17 no.1 pp. 22-26
- ISSN:
- 1875-5364
- Subject:
- Cirsium arvense; Oriental traditional medicine; animal ovaries; antineoplastic activity; cell lines; chemical structure; colorectal neoplasms; cytotoxicity; food plants; humans; inhibitory concentration 50; ovarian neoplasms; secretion; spectral analysis; triterpenoids; tumor necrosis factor-alpha
- Abstract:
- ... Guided by TNF-α secretion inhibitory activity assay, four taraxastane-type triterpenoids, including two new ones, 22-oxo-20-taraxasten-3β, 30-diol (1) and 22α-hydroxy-20-taraxasten-30β, 30-triol (2), have been obtained from an active fraction of the petroleum ether-soluble extract of the the medicinal and edible plant Cirsium setosum. Their structures were elucidated by spectroscopic data and CD d ...
- DOI:
- 10.1016/S1875-5364(19)30005-6
- https://doi.org/10.1016/S1875-5364(19)30005-6
- Author:
- Hyun Yang; Young Ho Lee; Sang R. Lee; Pelin Kaya; Eui-Ju Hong; Hye Won Lee
- Source:
- Journal of ethnopharmacology 2020 v.248 pp. 112300
- ISSN:
- 0378-8741
- Subject:
- Oriental traditional medicine; androgens; animal models; animal ovaries; blood serum; enzymes; estrogens; females; follicle-stimulating hormone; genes; gonadotropin receptors; in vivo studies; luteinizing hormone; polycystic ovary syndrome; rats; steroid receptors; steroids
- Abstract:
- ... Mahuang-Tang (MHT) has traditionally been used in Asia to treat a variety of diseases, such as fever without sweating, joint pain, lower back pain, asthma, and gynecological conditions. Polycystic ovary syndrome (PCOS) is a kind of gynecological disease that causes amenorrhea, infertility, and menopausal and urogenital disorders that could benefit from MHT treatment.In this study, we examined the ...
- DOI:
- 10.1016/j.jep.2019.112300
- https://doi.org/10.1016/j.jep.2019.112300
- Author:
- Yang SHU; Mei CAO; Zhong-Qiong YIN; Ping LI; Tai-Qiang LI; Xing-Fa LONG; Lian-Fa ZHU; Ren-Yong JIA; Shu-Jun DAI; Jian ZHAO
- Source:
- Chinese journal of natural medicines 2015 v.13 no.2 pp. 119-126
- ISSN:
- 1875-5364
- Subject:
- Oriental traditional medicine; adverse effects; animal ovaries; cortex; females; fetal death; histopathology; mice; pregnancy rate; reproductive toxicology; saponins; teratogenicity; toxicity testing; uterus
- Abstract:
- ... Saponin frsom Cortex Albiziae (SCA) are extensively used in the clinical treatment of tumor and depression. However, SCA may cause several adverse effects, including reproductive toxicity. The present study was designed to assess the mechanism by which SCA cause reproductive toxicity in female mice. The general reproductive toxicity testing was accomplished in female Kunming mice. The animals were ...
- DOI:
- 10.1016/S1875-5364(15)60015-2
- https://doi.org/10.1016/S1875-5364(15)60015-2