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You searched for: Subject albendazole Remove constraint Subject: albendazole Subject acetonitrile Remove constraint Subject: acetonitrile Subject term acetonitrile Remove constraint Subject term: acetonitrile Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Multi-residue methodology for quantification of antiparasitics in hen eggs by LC-MS/MS: development, validation and application to 348 samples from Brazil

Author:
Caroline A. Tomaszewski; Fabiano Barreto; Lucas S. Barnet; Louise Jank; Tania Mara Pizzolato
Source:
Food additives & contaminants 2022 v.39 no.8 pp. 1412-1423
ISSN:
1944-0057
Subject:
acetonitrile; albendazole; eggs; fenbendazole; fipronil; ivermectin; maximum residue limits; mebendazole; metabolites; oxibendazole; sodium chloride; solvents; sulfoxides; Brazil
Abstract:
... Analytical methodology for quantification of 15 antiparasitic drugs and their respective metabolites in laying hen eggs was optimized and validated. The method uses acetonitrile as solvent extraction, sodium chloride for salting-out, low-temperature purification and analysis by LC-MS/MS. A total of 348 egg samples were collected in 11 states of Brazil and 50% of the total samples presented antipar ...
DOI:
10.1080/19440049.2022.2093984

2. New and sensitive HPLC-UV method for concomitant quantification of a combination of antifilariasis drugs in rat plasma and organs after simultaneous oral administration

Author:
Andi Dian Permana; Elly Wahyudin; Ismail; Muh. Nur Amir; Muh. Raihan; Qonita Kurnia Anjani; Emilia Utomo; Patricia Layadi; Ryan F. Donnelly
Source:
Analytical methods 2021 v.13 no.7 pp. 933-945
ISSN:
1759-9679
Subject:
Bancroftian filariasis; Food and Drug Administration; acetonitrile; albendazole; doxycycline; high performance liquid chromatography; ivermectin; metabolites; oral administration; pharmacokinetics; rats; sulfoxides; toxicology
Abstract:
... A combination treatment comprising ivermectin (IVM), albendazole (ABZ) and doxycycline (DOX) is often prescribed for lymphatic filariasis patients. Nevertheless, there has not been an analytical method established and documented to determine these compounds simultaneously. Herein, we report a new high-performance liquid chromatographic method coupled with a UV detector (HPLC-UV) to quantify these ...
DOI:
10.1039/d0ay02258f

3. Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection

Author:
Zhaoyuan He; Zhixiang Diao; Yawen Guo; Kaizhou Xie; Lan Chen; Chun Xue; Yang Lu; Jinyuan Chen; Tao Zhang
Source:
Foods 2021 v.10 no.10 pp. -
ISSN:
2304-8158
Subject:
acetonitrile; albendazole; aqueous solutions; chickens; ducks; ethyl acetate; formic acid; geese; liquid-liquid extraction; maximum residue limits; metabolites; muscles; solid phase extraction; sulfoxides; swine; triethylamine
Abstract:
... A fast, simple and efficient ultrahigh-performance liquid chromatography-fluorescence detection (UPLC-FLD) method for the determination of residues of albendazole (ABZ) and its three metabolites, albendazole sulfone (ABZ-SO₂), albendazole sulfoxide (ABZ-SO), and albendazole-2-aminosulfone (ABZ-2NH₂-SO₂), in pig and poultry muscle (chicken, duck and goose) was established. The samples were extracte ...
DOI:
10.3390/foods10102350

4. Focused ultrasound-based extraction for target analysis and suspect screening of organic xenobiotics in fish muscle

Author:
M. Musatadi; B. González-Gaya; M. Irazola; A. Prieto; N. Etxebarria; M. Olivares; O. Zuloaga
Source:
Science of the total environment 2020 v.740 pp. 139894
ISSN:
0048-9697
Subject:
Chelon labrosus; acetonitrile; albendazole; bass; bream; caprolactam; cold; environment; estuaries; hake; insects; liquid chromatography; markets; mass spectrometry; mebendazole; muscles; nootkatone; phthalates; quantitative analysis; shrimp; sulfates; ultrasonic treatment; xenobiotics; Spain
Abstract:
... The development of multitarget and/or suspect screening methods for the analysis of xenobiotics in fish samples is compulsory due to the lack of works in the literature where a deep evaluation of the variables affecting extraction and clean-up steps is performed. The aim of the present work was to optimize and validate a multitarget (180 compounds) method for the analysis of priority and emerging ...
DOI:
10.1016/j.scitotenv.2020.139894

5. Determination of antibiotic residues in frozen poultry by a solid-phase dispersion method using liquid chromatography-triple quadrupole mass spectrometry

Author:
Abdulrasaq O. Oyedeji; Titus A.M. Msagati; Akan B. Williams; Nsikak U. Benson
Source:
Toxicology reports 2019 v.6 pp. 951-956
ISSN:
2214-7500
Subject:
acetonitrile; albendazole; chickens; electrospray ionization mass spectrometry; gizzard; ionization; liquid chromatography; muscles; risk; solid phase extraction; sulfamethoxazole; tandem mass spectrometry; toxicology; Nigeria
Abstract:
... Importation of poultry produce into Nigeria through its land borders has heightened, notwithstanding the government’s ban on such products. This study examined imported frozen poultry products for antibiotic residues considering their health implications. A solid-phase extraction method using liquid chromatography-tandem mass spectrometry in the positive and negative electrospray ionisation and th ...
DOI:
10.1016/j.toxrep.2019.09.005

6. Determination of six veterinary pharmaceuticals in egg by liquid chromatography: Chemometric optimization of a novel air assisted-dispersive liquid-liquid microextraction by solid floating organic drop

Author:
Carla M. Teglia; Lucia Gonzalo; María J. Culzoni; Héctor C. Goicoechea
Source:
Food chemistry 2019 v.273 pp. 194-202
ISSN:
0308-8146
Subject:
acetonitrile; air; albendazole; chemometrics; chloramphenicol; eggs; enrofloxacin; liquid chromatography; liquid-phase microextraction; methanol; methylene chloride; nicarbazin; pH; sodium phosphate; solidification; solvents; trimethoprim; veterinary drugs; zinc sulfate
Abstract:
... Two extraction strategies for albendazole, chloramphenicol, trimethoprim, enrofloxacin, oxitetracycline and nicarbazin in egg were optimized for its quantitation by liquid chromatography. First, two designs were built to find out the optimized condition for the air assisted-dispersive liquid-liquid microextraction based on solidification of organic drop: a fractional factorial and a central compos ...
DOI:
10.1016/j.foodchem.2017.08.034

7. Development of a liquid chromatography–tandem mass spectrometry method with modified QuEChERS extraction for the quantification of mebendazole and its metabolites, albendazole and its metabolites, and levamisole in edible tissues of aquatic animals

Author:
Ning Xu; Jing Dong; Yibin Yang; Yongtao Liu; Qiuhong Yang; Xiaohui Ai
Source:
Food chemistry 2018 v.269 pp. 442-449
ISSN:
0308-8146
Subject:
Megalobrama amblycephala; acetonitrile; albendazole; centrifugation; detection limit; eel; levamisole; liquid chromatography; liquids; magnesium sulfate; mebendazole; metabolites; muscles; quantitative analysis; shrimp; sodium chloride; tandem mass spectrometry; tissues; turtles
Abstract:
... A liquid chromatography–tandem mass spectrometry quantitative method was developed for determining mebendazole and its metabolites, albendazole and its metabolites, and levamisole in muscles of bluntnose black bream, shrimp, eel and turtle based on modified QuEChERS methodology. The method included 2 g of the muscle matrix with 10 mL acetonitrile, and 0.8 g of magnesium sulphate and 0.2 g of sodiu ...
DOI:
10.1016/j.foodchem.2018.07.017

8. Alternative Green Preconcentration Approach Based on Ultrasound-Assisted Surfactant-Enhanced Emulsification Microextraction and HPLC for Determination of Benzimidazole Anthelmintics in Milk Formulae

Author:
Tittaya Boontongto; Yanawath Santaladchaiyakit; Rodjana Burakham
Source:
Chromatographia 2014 v.77 no.21-22 pp. 1557-1562
ISSN:
0009-5893
Subject:
acetonitrile; albendazole; benzimidazole; detection limit; emulsifiers; emulsifying; fenbendazole; flubendazole; formic acid; high performance liquid chromatography; mebendazole; microextraction; milk; niclosamide; oxfendazole; solvents; surfactants; ultrasonic treatment
Abstract:
... An alternative green microextraction method based on ultrasound-assisted surfactant-enhanced emulsification microextraction (UASEME) using a low-density extraction solvent coupled with HPLC has been developed for preconcentration and determination of six benzimidazole anthelmintics, namely, oxfendazole, albendazole, mebendazole, flubendazole, fenbendazole, and niclosamide. The separation was achie ...
DOI:
10.1007/s10337-014-2747-0

9. Effect of the water content on the retention and enantioselectivity of albendazole and fenbendazole sulfoxides using amylose-based chiral stationary phases in organic–aqueous conditions

Author:
Sabrina Materazzo; Simone Carradori; Rosella Ferretti; Bruno Gallinella; Daniela Secci; Roberto Cirilli
Source:
Journal of chromatography 2014 v.1327 pp. 73-79
ISSN:
0021-9673
Subject:
acetonitrile; albendazole; chemoselectivity; enantiomers; enantioselectivity; fenbendazole; high performance liquid chromatography; metabolites; polysaccharides; sulfides; water content
Abstract:
... Four commercially available immobilized amylose-derived CSPs (Chiralpak IA-3, Chiralpak ID-3, Chiralpak IE-3 and Chiralpak IF-3) were used in the HPLC analysis of the chiral sulfoxides albendazole (ABZ-SO) and fenbendazole (FBZ-SO) and their in vivo sulfide precursor (ABZ and FBZ) and sulfone metabolite (ABZ-SO2 and FBZ-SO2) under organic–aqueous mode. U-shape retention maps, established by varyin ...
DOI:
10.1016/j.chroma.2013.12.051

10. Setting up the chromatographic analysis of anthelmintics using the “Crossed D-Optimal” experimental design methodology

Author:
Nikolaos G. Margaritelis; Catherine K. Markopoulou; John E. Koundourellis
Source:
Analytical methods 2013 v.5 no.13 pp. 3334-3346
ISSN:
1759-9679
Subject:
acetonitrile; albendazole; ammonium acetate; buffers; chemical species; cross-over studies; experimental design; high performance liquid chromatography; levamisole; light scattering; mebendazole; methanol; niclosamide; pH; praziquantel; quantitative analysis; regression analysis; solvents; thiabendazole
Abstract:
... An “experimental design” methodology was applied to optimize the chromatographic separation and quantitative determination of six anthelmintics levamisole (LEV), thiabendazole (THI), mebendazole (MEB), albendazole (ALB), praziquantel (PRA) and niclosamide (NICL) by HPLC. Based on the “Crossed D-Optimal” criterion, the participation of three mixed solvents in the mobile phase (methanol, water and a ...
DOI:
10.1039/c3ay40555a

11. Development of a liquid chromatography–tandem mass spectrometry with pressurized liquid extraction method for the determination of benzimidazole residues in edible tissues

Author:
Dongmei Chen; Yanfei Tao; Huahai Zhang; Yuanhu Pan; Zhenli Liu; Lingli Huang; Yulian Wang; Dapeng Peng; Xu Wang; Menghong Dai; Zonghui Yuan
Source:
Journal of chromatography 2011 v.879 no.19 pp. 1659-1667
ISSN:
1570-0232
Subject:
acetonitrile; albendazole; animal products; benzimidazole; cattle; chickens; fenbendazole; hexane; high performance liquid chromatography; liver; mebendazole; metabolites; monitoring; muscles; quantitative analysis; sheep; solvents; swine; tandem mass spectrometry; tissues
Abstract:
... A confirmatory and quantitative method of liquid chromatography–tandem mass spectrometry (LC–MS/MS) combined with a pressure liquid extraction (PLE) was developed for the determination of 11 benzimidazole and 10 metabolites of albendazole, fenbendazole and mebendazole in the muscles and livers of swine, cattle, sheep and chicken. For sample preparation, we used an automated technique of PLE method ...
DOI:
10.1016/j.jchromb.2011.04.004

12. Determination of two metabolites of albendazole, albendazole-sulfoxide and albendazole-sulfone in cow's milk using an HPLC method —A systematic approach to optimise extraction conditions

Author:
Zs. Romvári; J. Fekete; S. Kemény; G. Pokol; I. Gebefügi; A. Kettrup
Source:
Chromatographia 1998 v.48 no.11-12 pp. 777-784
ISSN:
0009-5893
Subject:
acetonitrile; albendazole; detection limit; humans; metabolites; methanol; milk; phosphates; reversed-phase high performance liquid chromatography
Abstract:
... Reversed phase HPLC methods for the determination of two metabolites of albendazole in cow's milk are described. Albendazole is an anthelmintic agent used both in veterinary and human practice. Its main metabolites are albendazole-sulfoxide and albendazole-sulfone. The separation of the two metabolites was performed on a μ-Bondapak C-18 column using an acetonitrile/methanol/phosphate buffer as mob ...
DOI:
10.1007/BF02467647