U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject animal injuries Remove constraint Subject: animal injuries Subject animal models Remove constraint Subject: animal models Subject term cerebrospinal fluid Remove constraint Subject term: cerebrospinal fluid
Start Over

Search

2  Search Results

1 - 2 of 2
Number of results to display per page

Search Results

1. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier

Author:
Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:
0006-291X
Subject:
CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:
... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:
10.1016/j.bbrc.2019.03.002

2. Real-time assessment of spinal cord microperfusion in a porcine model of ischemia/reperfusion

Author:
Behem Christoph R.; Friedheim Till; Wipper Sabine H.; Pinnschmidt Hans O.; Graessler Michael F.; Gaeth Catharina; Holthusen Hannes; Rapp Adina; Suntrop Timo; Haunschild Josephina; Etz Christian D.; Trepte Constantin J. C.
Source:
Journal of visualized experiments 2020 no.166 pp. e62047
ISSN:
1940-087X
Subject:
animal injuries; animal models; aorta; cerebrospinal fluid; drainage; fluorescence; hemodynamics; histopathology; ischemia; microparticles; oxygen; patients; spinal cord; swine
Abstract:
... Spinal cord injury is a devastating complication of aortic repair. Despite developments for the prevention and treatment of spinal cord injury, its incidence is still considerably high and therefore, influences patient outcome. Microcirculation plays a key role in tissue perfusion and oxygen supply and is often dissociated from macrohemodynamics. Thus, direct evaluation of spinal cord microcircula ...
DOI:
10.3791/62047